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22 results on '"Girst, Stefanie"'

11. Proton pencil minibeam irradiation of an in-vivo mouse ear model spares healthy tissue dependent on beam size

Author

Sammer, Matthias, primary, Zahnbrecher, Esther, additional, Dobiasch, Sophie, additional, Girst, Stefanie, additional, Greubel, Christoph, additional, Ilicic, Katarina, additional, Reindl, Judith, additional, Schwarz, Benjamin, additional, Siebenwirth, Christian, additional, Walsh, Dietrich W. M., additional, Combs, Stephanie E., additional, Dollinger, Günther, additional, and Schmid, Thomas E., additional

Published
2019
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13. DNA damage interactions on both nanometer and micrometer scale determine overall cellular damage

Author

Ilicic, Katarina, Greubel, Christoph, Girst, Stefanie, Reindl, Judith, Sammer, Matthias, Schwarz, Benjamin, Siebenwirth, Christian, Walsh, Dietrich W. M., Schmid, Thomas E., Scholz, Michael, and Dollinger, Günther

Abstract

Scientific reports 8(1), 16063 (2018). doi:10.1038/s41598-018-34323-9, Published by Macmillan Publishers Limited, part of Springer Nature, [London]

Published
2018
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14. Beam size limit for pencil minibeam radiotherapy determined from side effects in an in-vivo mouse ear model

Author

Sammer, Matthias, primary, Teiluf, Katharina, additional, Girst, Stefanie, additional, Greubel, Christoph, additional, Reindl, Judith, additional, Ilicic, Katarina, additional, Walsh, Dietrich W. M., additional, Aichler, Michaela, additional, Walch, Axel, additional, Combs, Stephanie E., additional, Wilkens, Jan J., additional, Dollinger, Günther, additional, and Schmid, Thomas E., additional

Published
2019
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15. DNA damage interactions on both nanometer and micrometer scale determine overall cellular damage

Author

Friedrich, Thomas, primary, Ilicic, Katarina, additional, Greubel, Christoph, additional, Girst, Stefanie, additional, Reindl, Judith, additional, Sammer, Matthias, additional, Schwarz, Benjamin, additional, Siebenwirth, Christian, additional, Walsh, Dietrich W. M., additional, Schmid, Thomas E., additional, Scholz, Michael, additional, and Dollinger, Günther, additional

Published
2018
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16. Live cell imaging of mitochondria following targeted irradiation in situ reveals rapid and highly localized loss of membrane potential

Author

Walsh, Dietrich W. M., primary, Siebenwirth, Christian, additional, Greubel, Christoph, additional, Ilicic, Katarina, additional, Reindl, Judith, additional, Girst, Stefanie, additional, Muggiolu, Giovanna, additional, Simon, Marina, additional, Barberet, Philippe, additional, Seznec, Hervé, additional, Zischka, Hans, additional, Multhoff, Gabriele, additional, Schmid, Thomas E., additional, and Dollinger, Guenther, additional

Published
2017
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18. Live cell imaging at the Munich ion microbeam SNAKE – a status report

Author

Drexler, Guido A, Siebenwirth, Christian, Drexler, Sophie E, Girst, Stefanie, Greubel, Christoph, Dollinger, Günther, and Friedl, Anna A

Subjects
Fluorescence microscopy, Ions, Cells, Radiobiology, Review, equipment and supplies, Molecular Imaging, Particles, Live-cell imaging, Oncology, Radiology Nuclear Medicine and imaging, Humans, Particle Accelerators, Micro-irradiation
Abstract

Ion microbeams are important tools in radiobiological research. Still, the worldwide number of ion microbeam facilities where biological experiments can be performed is limited. Even fewer facilities combine ion microirradiation with live-cell imaging to allow microscopic observation of cellular response reactions starting very fast after irradiation and continuing for many hours. At SNAKE, the ion microbeam facility at the Munich 14 MV tandem accelerator, a large variety of biological experiments are performed on a regular basis. Here, recent developments and ongoing research projects at the ion microbeam SNAKE are presented with specific emphasis on live-cell imaging experiments. An overview of the technical details of the setup is given, including examples of suitable biological samples. By ion beam focusing to submicrometer beam spot size and single ion detection it is possible to target subcellular structures with defined numbers of ions. Focusing of high numbers of ions to single spots allows studying the influence of high local damage density on recruitment of damage response proteins. Electronic supplementary material The online version of this article (doi:10.1186/s13014-015-0350-7) contains supplementary material, which is available to authorized users.

Published
2015

19. Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair

Author

Penterling, Corina, primary, Drexler, Guido A., additional, Böhland, Claudia, additional, Stamp, Ramona, additional, Wilke, Christina, additional, Braselmann, Herbert, additional, Caldwell, Randolph B., additional, Reindl, Judith, additional, Girst, Stefanie, additional, Greubel, Christoph, additional, Siebenwirth, Christian, additional, Mansour, Wael Y., additional, Borgmann, Kerstin, additional, Dollinger, Günther, additional, Unger, Kristian, additional, and Friedl, Anna A., additional

Published
2016
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20. A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells

Author

Buchfellner, Andrea, primary, Yurlova, Larisa, additional, Nüske, Stefan, additional, Scholz, Armin M., additional, Bogner, Jacqueline, additional, Ruf, Benjamin, additional, Zolghadr, Kourosh, additional, Drexler, Sophie E., additional, Drexler, Guido A., additional, Girst, Stefanie, additional, Greubel, Christoph, additional, Reindl, Judith, additional, Siebenwirth, Christian, additional, Romer, Tina, additional, Friedl, Anna A., additional, and Rothbauer, Ulrich, additional

Published
2016
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