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1. Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study)

Author

Valdés, Sergio, Doulatram-Gamgaram, Viyey, Maldonado-Araque, Cristina, Lago-Sampedro, Ana, García-Escobar, Eva, García-Serrano, Sara, García-Vivanco, Marta, Garrido Juan, Luis, Theobald, Mark Richard, Gil, Victoria, Martín-Llorente, Fernando, Ocon, Pilar, Calle-Pascual, Alfonso, Castaño, Luis, Delgado, Elías, Menendez, Edelmiro, Franch-Nadal, Josep, Gaztambide, Sonia, Girbés, Joan, Chaves, F Javier, Galán-García, José L, Aguilera-Venegas, Gabriel, Gutierrez-Repiso, Carolina, Fernández-García, José Carlos, Colomo, Natalia, Soriguer, Federico, García-Fuentes, Eduardo, and Rojo-Martínez, Gemma

Published
2022
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2. Association between exposure to air pollution and blood lipids in the general population of Spain.

Author

Valdés, Sergio, Doulatram‐Gamgaram, Viyey, Maldonado‐Araque, Cristina, García‐Escobar, Eva, García‐Serrano, Sara, Oualla‐Bachiri, Wasima, García‐Vivanco, Marta, Garrido, Juan Luis, Gil, Victoria, Martín‐Llorente, Fernando, Calle‐Pascual, Alfonso, Castaño, Luis, Delgado, Elías, Menéndez, Edelmiro, Franch‐Nadal, Josep, Gaztambide, Sonia, Girbés, Joan, Chaves, F. Javier, Galán‐García, José L., and Aguilera‐Venegas, Gabriel

Subjects
AIR pollution, BLOOD lipids, AIR pollutants, PARTICULATE matter, AIR quality
Abstract

Background and Aims: We aimed to assess the associations of exposure to air pollutants and standard and advanced lipoprotein measures, in a nationwide sample representative of the adult population of Spain. Methods: We included 4647 adults (>18 years), participants in the national, cross‐sectional, population‐based di@bet.es study, conducted in 2008–2010. Standard lipid measurements were analysed on an Architect C8000 Analyzer (Abbott Laboratories SA). Lipoprotein analysis was made by an advanced 1H‐NMR lipoprotein test (Liposcale®). Participants were assigned air pollution concentrations for particulate matter <10 μm (PM10), <2.5 μm (PM2.5) and nitrogen dioxide (NO2), corresponding to the health examination year, obtained by modelling combined with measurements taken at air quality stations (CHIMERE chemistry‐transport model). Results: In multivariate linear regression models, each IQR increase in PM10, PM2.5 and NO2 was associated with 3.3%, 3.3% and 3% lower levels of HDL‐c and 1.3%, 1.4% and 1.1% lower HDL particle (HDL‐p) concentrations (p <.001 for all associations). In multivariate logistic regression, there was a significant association between PM10, PM2.5 and NO2 concentrations and the odds of presenting low HDL‐c (<40 mg/dL), low HDL‐p (

Published
2024
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3. Association between exposure to air pollution and blood lipids in the general population of Spain

Author

Valdés, Sergio, primary, Doulatram‐Gamgaram, Viyey, additional, Maldonado‐Araque, Cristina, additional, García‐Escobar, Eva, additional, García‐Serrano, Sara, additional, Oualla‐Bachiri, Wasima, additional, García‐Vivanco, Marta, additional, Garrido, Juan Luis, additional, Gil, Victoria, additional, Martín‐Llorente, Fernando, additional, Calle‐Pascual, Alfonso, additional, Castaño, Luis, additional, Delgado, Elías, additional, Menéndez, Edelmiro, additional, Franch‐Nadal, Josep, additional, Gaztambide, Sonia, additional, Girbés, Joan, additional, Chaves, F. Javier, additional, Galán‐García, José L., additional, Aguilera‐Venegas, Gabriel, additional, Vallvé, Joan Carles, additional, Amigó, Núria, additional, Guardiola, Montse, additional, Ribalta, Josep, additional, and Rojo‐Martínez, Gemma, additional

Published
2023
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5. Iodine Deficiency and Mortality in Spanish Adults: Di@bet.es Study

Author

Maldonado-Araque, Cristina, primary, Valdés, Sergio, additional, Badía-Guillén, Rocío, additional, Lago-Sampedro, Ana, additional, Colomo, Natalia, additional, Garcia-Fuentes, Eduardo, additional, Gutierrez-Repiso, Carolina, additional, Goday, Albert, additional, Calle-Pascual, Alfonso, additional, Castaño, Luis, additional, Castell, Conxa, additional, Delgado, Elías, additional, Menendez, Edelmiro, additional, Franch-Nadal, Josep, additional, Gaztambide, Sonia, additional, Girbés, Joan, additional, Chaves, Francisco Javier, additional, Soriguer, Federico, additional, and Rojo-Martínez, Gemma, additional

Published
2021
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6. Ambient temperature and prevalence of diabetes and insulin resistance in the Spanish population: Di@bet.es study

Author

Valdés, Sergio, primary, Doulatram-Gamgaram, Viyey, additional, Lago, Ana, additional, García Torres, Francisca, additional, Badía-Guillén, Rocío, additional, Olveira, Gabriel, additional, Goday, Albert, additional, Calle-Pascual, Alfonso, additional, Castaño, Luis, additional, Castell, Conxa, additional, Delgado, Elías, additional, Menendez, Edelmiro, additional, Franch-Nadal, Josep, additional, Gaztambide, Sonia, additional, Girbés, Joan, additional, Gomis, Ramón, additional, Ortega, Emilio, additional, Galán-García, José L, additional, Aguilera-Venegas, Gabriel, additional, Soriguer, Federico, additional, and Rojo-Martínez, Gemma, additional

Published
2019
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7. Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study

Author

Maldonado-Araque, Cristina, primary, Valdés, Sergio, additional, Lago-Sampedro, Ana, additional, Lillo-Muñoz, Juan Antonio, additional, Garcia-Fuentes, Eduardo, additional, Perez-Valero, Vidal, additional, Gutierrez-Repiso, Carolina, additional, Goday, Albert, additional, Urrutia, Ines, additional, Peláez, Laura, additional, Calle-Pascual, Alfonso, additional, Castaño, Luis, additional, Castell, Contxa, additional, Delgado, Elias, additional, Menendez, Edelmiro, additional, Franch-Nadal, Josep, additional, Gaztambide, Sonia, additional, Girbés, Joan, additional, Ortega, Emilio, additional, Vendrell, Joan, additional, Chacón, Matilde R., additional, Chaves, Felipe J., additional, Soriguer, Federico, additional, and Rojo-Martínez, Gemma, additional

Published
2018
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8. Reference values for TSH may be inadequate to define hypothyroidism in persons with morbid obesity: Di@bet.es study

Author

Valdés, Sergio, primary, Maldonado-Araque, Cristina, additional, Lago-Sampedro, Ana, additional, Lillo-Muñoz, Juan Antonio, additional, Garcia-Fuentes, Eduardo, additional, Perez-Valero, Vidal, additional, Gutiérrez-Repiso, Carolina, additional, Garcia-Escobar, Eva, additional, Goday, Albert, additional, Urrutia, Inés, additional, Peláez, Laura, additional, Calle-Pascual, Alfonso, additional, Bordiú, Elena, additional, Castaño, Luis, additional, Castell, Conxa, additional, Delgado, Elias, additional, Menéndez, Edelmiro, additional, Franch-Nadal, Josep, additional, Gaztambide, Sonia, additional, Girbés, Joan, additional, Ortega, Emilio, additional, Vendrell, Joan, additional, Chacón, Matilde R., additional, Javier Chaves, F., additional, Soriguer, Federico, additional, and Rojo-Martínez, Gemma, additional

Published
2017
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9. Population-Based National Prevalence of Thyroid Dysfunction in Spain and Associated Factors: Di@bet.es Study

Author

Valdés, Sergio, primary, Maldonado-Araque, Cristina, additional, Lago-Sampedro, Ana, additional, Lillo, J. Antonio, additional, Garcia-Fuentes, Eduardo, additional, Perez-Valero, Vidal, additional, Gutierrez-Repiso, Carolina, additional, Ocon-Sanchez, Pilar, additional, Goday, Albert, additional, Urrutia, Ines, additional, Peláez, Laura, additional, Calle-Pascual, Alfonso, additional, Bordiú, Elena, additional, Castaño, Luis, additional, Castell, Conxa, additional, Delgado, Elias, additional, Menendez, Edelmiro, additional, Franch, Josep, additional, Gaztambide, Sonia, additional, Girbés, Joan, additional, Ortega, Emilio, additional, Lopez-Alba, Alfonso, additional, Chaves, Felipe J., additional, Vendrell, Joan, additional, Chacón, Matilde R., additional, Soriguer, Federico, additional, and Rojo-Martínez, Gemma, additional

Published
2017
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10. Population-Based National Prevalence of Thyroid Dysfunction in Spain and Associated Factors: Study.

Author

Valdés, Sergio, Maldonado-Araque, Cristina, Lago-Sampedro, Ana, Lillo, J. Antonio, Garcia-Fuentes, Eduardo, Perez-Valero, Vidal, Gutierrez-Repiso, Carolina, Ocon-Sanchez, Pilar, Goday, Albert, Urrutia, Ines, Peláez, Laura, Calle-Pascual, Alfonso, Bordiú, Elena, Castaño, Luis, Castell, Conxa, Delgado, Elias, Menendez, Edelmiro, Franch, Josep, Gaztambide, Sonia, and Girbés, Joan

Subjects
THYROID diseases, DISEASE prevalence, TRIIODOTHYRONINE, HYPOTHYROIDISM, PUBLIC health
Abstract

Background: The aim of this study was to investigate the national prevalence of thyroid dysfunction in Spain and its association with various clinical, environmental, and demographic variables. Methods: The study included 4554 subjects (42.4% men) with a mean age of 50 years (range 18-93 years), who were participants in a national, cross-sectional, population-based survey conducted in 2009-2010. Data gathered included clinical and demographic characteristics, physical examination, and blood sampling. Thyrotropin, free thyroxine, free triiodothyronine, and thyroid peroxidase antibody (TPOAb) concentrations were analyzed by electrochemiluminescence. Urinary iodine (UI) levels were measured in an isolated urine sample. Results: The prevalence of treated hypothyroidism, untreated subclinical hypothyroidism, and untreated clinical hypothyroidism was 4.2% [confidence interval (CI) 3.6-4.9%], 4.6% [CI 4.0-5.2%], and 0.3% [CI 0.1-0.5%], respectively. The prevalence of total hypothyroidism (including all fractions) was 9.1% [CI 8.2-10.0%]. The prevalence of total hyperthyroidism was 0.8% [CI 0.6-1.1]. A total of 7.5% [CI 6.7-8.3%] of the population tested positive for TPOAbs (≥50 IU/mL). In multivariate logistic regression models, TPOAbs were strongly associated with both hypothyroidism ( p < 0.001) and hyperthyroidism ( p = 0.005), whereas high UI levels (>200 μg/g creatinine) were associated with hypothyroidism ( p < 0.001). The positive association between UI and hypothyroidism remained for both treated ( p < 0.001) and untreated ( p < 0.05) hypothyroidism, whereas it was especially significant for non-autoimmune (TPOAbs negative) forms ( p < 0.001). At UI levels ≥200 μg/g, there was a positive correlation between UI and thyrotropin levels (β = 0.152, p < 0.001) and a negative correlation between UI and free triiodothyronine levels (β = −0.134, p = 0.001). Conclusion: According to the data, a large proportion (10%) of the Spanish population has some evidence of thyroid dysfunction. High TPOAb concentrations were associated with both hypo- and hyperthyroidism, whereas high UI concentrations were associated with hypothyroidism. [ABSTRACT FROM AUTHOR]

Published
2017
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11. Faristol

Author

Blanch, Xavier, Girbés, Joan Carles, Figueras Adell, Núria, Aloy, Josep Maria, Carbó, Joaquim, and Rius, Maria

Subjects
libros para niños, lectura, literatura infantil y juvenil, animación
Abstract

En el artículo cada autor relata una animación lectora que recuerda especialmente. Cataluña Universitat de Barcelona. Biblioteca de Ciències de l'Educació; Passeig de la Vall d'Hebron, 171; 08035 Barcelona; +34934021035; +34934029077; ESP

Published
2004

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