180 results on '"Gimeno, Ruth E."'
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2. Leveraging the Gut to Treat Metabolic Disease
3. Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart
4. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
5. GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice
6. The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL
7. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept
8. FGF21-based pharmacotherapy – potential utility for metabolic disorders
9. Myogenic Gene Expression Signature Establishes That Brown and White Adipocytes Originate from Distinct Cell Lineages
10. Molecular Identification of Microsomal Acyl-CoA:Glycerol-3-Phosphate Acyltransferase, a Key Enzyme in De Novo Triacylglycerol Synthesis
11. Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity
12. Bidirectional Modulation of Adipogenesis by the Secreted Protein Ccdc80/DRO1/URB
13. Yeast SEC16 Gene Encodes a Multidomain Vesicle Coat Protein That Interacts with Sec23p
14. SED4 Encodes a Yeast Endoplasmic Reticulum Protein That Binds Sec16p and Participates in Vesicle Formation
15. The Sweetest Thing: Regulation of Macronutrient Preference by FGF21
16. Agonistic TAM-163 antibody targeting tyrosine kinase receptor-B: Applying mechanistic modeling to enable preclinical to clinical translation and guide clinical trial design
17. A Stable Analog of Adropin Does Not Improve Glucose Homeostasis in Diet-Induced Obese Mice
18. Loss of Coiled-Coil Domain Containing 80 Negatively Modulates Glucose Homeostasis in Diet-Induced Obese Mice
19. Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion
20. Angiopoietin-like protein 8 differentially regulates ANGPTL3 and ANGPTL4 during postprandial partitioning of fatty acids
21. Disruption of G Protein-Coupled Receptor 39 Impairs Insulin Secretion in Vivo
22. Adipose tissue as an active endocrine organ: recent advances
23. Fatty acid transport proteins
24. Normal Food Intake and Body Weight in Mice Lacking the G Protein-Coupled Receptor GPR39
25. Estrogen Related Receptor α (ERRα) Binding Proteins: Possible Roles for GAPDH and Oxidative Stress in ERRα Function: 1913-P
26. Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle
27. Cloning and Characterization of an Uncoupling Protein Homolog: A Potential Molecular Mediator of Human Thermogenesis
28. Fatty acid transport proteins: a current view of a growing family
29. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial
30. Existence of uncoupling protein-2 antigen in isolated mitochondria from various tissues
31. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial
32. The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue
33. FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency
34. Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1
35. Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity
36. Activation of TrkB with TAM-163 Results in Opposite Effects on Body Weight in Rodents and Non-Human Primates
37. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.
38. Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases
39. GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis
40. Disruption of GPR39 Impairs Insulin Secretion In Vivo
41. Thematic Review Series: Glycerolipids. Mammalian glycerol-3-phosphate acyltransferases: new genes for an old activity
42. Molecular Identification of a Novel Mammalian Brain Isoform of Acyl-CoA:Lysophospholipid Acyltransferase with Prominent Ethanolamine Lysophospholipid Acylating Activity, LPEAT2
43. Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile
44. Inhibition of Gluconeogenesis through Transcriptional Activation of EGR1 and DUSP4 by AMP-activated Kinase
45. Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4
46. Targeted Deletion of FATP5 Reveals Multiple Functions in Liver Metabolism: Alterations in Hepatic Lipid Homeostasis
47. Mice Deleted for Fatty Acid Transport Protein 5 Have Defective Bile Acid Conjugation and Are Protected From Obesity
48. Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members
49. Targeted Deletion of Fatty Acid Transport Protein-4 Results in Early Embryonic Lethality
50. Characterization of a Heart-specific Fatty Acid Transport Protein
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