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4. Recovery from Acute Kidney Injury and Long-Term Prognosis following Acute Myocardial Infarction.

Author

Skalsky, Keren, Shiyovich, Arthur, Shechter, Alon, Gilutz, Harel, and Plakht, Ygal

Subjects
MYOCARDIAL infarction, ACUTE kidney failure, RECEIVER operating characteristic curves, MORTALITY, PROGNOSIS
Abstract

We investigated the recovery pattern from acute kidney injury (AKI) following acute myocardial infarction (AMI) and its association with long-term mortality. The retrospective study included AMI patients (2002–2027), who developed AKI during hospitalization. Creatinine (Cr) measurements were collected and categorized into 24 h timeframes up to 7 days from AKI diagnosis. The following groups of recovery patterns were defined: rapid (24–48 h)/no rapid and early (72–144 h)/no early recovery. Specific cut-off points for recovery at each AKI stage and timeframe were determined through receiver operating characteristic (ROC) curves. The probability of long-term (up to 10 years) mortality as a post-AKI recovery was investigated using a survival approach. Out of 17,610 AMI patients, 1069 developed AKI. For stage 1 AKI, patients with a Cr ratio <1.5 at 24 h and/or <1.45 at 48 h were defined as 'rapid recovery'; for stages 2–3 AKI, a Cr ratio <2.5 at 96 h was defined as 'early recovery'. Mortality risk in stage 1 AKI was higher among the non-rapidly recovered: AdjHR = 1.407; 95% CI: 1.086–1.824; p = 0.010. Among stages 2–3 AKI patients, the risk for long-term mortality was higher among patients who did not recover in the early period: AdjHR = 1.742; 95% CI: 1.085–2.797; p = 0.022. The absence of rapid recovery in stage 1 AKI and lack of early recovery in stages 2–3 AKI are associated with higher long-term mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Supplemental Material, AF_in_AMI__suppl_1-2-2020 - Early Atrial Fibrillation During Acute Myocardial Infarction May Not Be an Indication for Long-Term Anticoagulation

Author

Axelrod, Michal, Gilutz, Harel, Ygal Plakht, Greenberg, Dan, and Novack, Lena

Subjects
cardiovascular system, Cardiology, cardiovascular diseases
Abstract

Supplemental Material, AF_in_AMI__suppl_1-2-2020 for Early Atrial Fibrillation During Acute Myocardial Infarction May Not Be an Indication for Long-Term Anticoagulation by Michal Axelrod, Harel Gilutz, Ygal Plakht, Dan Greenberg and Lena Novack in Angiology

Published
2020
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