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300 results on '"Gilligan T"'

1. Recursive Partitioning Analysis to Define Prognostic Groups Using a Large Single Institution Experience of Multimodality Radiation Therapy for Bladder Cancer

Author

Nair, M., primary, Scarborough, J., additional, Gupta, S., additional, Gilligan, T., additional, Ornstein, M.C., additional, Wee, C., additional, Klein, E.A., additional, Haber, G.P., additional, Campbell, S., additional, Almassi, N., additional, Gill, B., additional, Berglund, R., additional, Lee, B., additional, Weight, C., additional, Gray, M., additional, Ciezki, J.P., additional, Stephans, K.L., additional, Tendulkar, R.D., additional, Scott, J.G., additional, and Mian, O.Y., additional

Published
2022
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5. DNA Extraction Method for Insects From Sticky Traps: Targeting a Low Abundance Pest, Phthorimaea absoluta (Lepidoptera: Gelechiidae), in Mixed Species Communities.

Author

Butterwort, V, Dansby, H, Zink, F A, Tembrock, L R, Gilligan, T M, Godoy, A, Braswell, W E, and Kawahara, A Y

Subjects
NUCLEIC acid isolation methods, GELECHIIDAE, LEPIDOPTERA, INTRODUCED insects, INSECTS, BIOLOGICAL invasions, BIODIVERSITY
Abstract

Invasive insects can cause catastrophic damage to ecosystems and cost billions of dollars each year due to management expenses and lost revenue. Rapid detection is an important step to prevent invasive insects from spreading, but improvements in detection capabilities are needed for bulk collections like those from sticky traps. Here we present a bulk DNA extraction method designed for the detection of Phthorimaea absoluta Meyrick (Lepidoptera: Gelechiidae), an invasive moth that can decimate tomato crops. We test the extraction method for insect specimens on sticky traps, subjected to different temperature and humidity conditions, and among mock insect communities left in the field for up to 21 d. We find that the extraction method yielded high success (>92%) in recovering target DNA across field and lab trials, without a decline in recovery after three weeks, across all treatments. These results may have a large impact on tomato growing regions where P. absoluta is in the early stages of invasion or not yet present. The extraction method can also be used to improve detection capabilities for other bulk insect collections, especially those using sticky traps, to the benefit of pest surveys and biodiversity studies. [ABSTRACT FROM AUTHOR]

Published
2022
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6. A DNA Extraction Method for Insects From Sticky Traps: Targeting a Low Abundance Pest, Phthorimaea absoluta(Lepidoptera: Gelechiidae), in Mixed Species Communities

Author

Butterwort, V, Dansby, H, Zink, F A, Tembrock, L R, Gilligan, T M, Godoy, A, Braswell, W E, and Kawahara, A Y

Abstract

Invasive insects can cause catastrophic damage to ecosystems and cost billions of dollars each year due to management expenses and lost revenue. Rapid detection is an important step to prevent invasive insects from spreading, but improvements in detection capabilities are needed for bulk collections like those from sticky traps. Here we present a bulk DNA extraction method designed for the detection of Phthorimaea absolutaMeyrick (Lepidoptera: Gelechiidae), an invasive moth that can decimate tomato crops. We test the extraction method for insect specimens on sticky traps, subjected to different temperature and humidity conditions, and among mock insect communities left in the field for up to 21 d. We find that the extraction method yielded high success (>92%) in recovering target DNA across field and lab trials, without a decline in recovery after three weeks, across all treatments. These results may have a large impact on tomato growing regions where P. absolutais in the early stages of invasion or not yet present. The extraction method can also be used to improve detection capabilities for other bulk insect collections, especially those using sticky traps, to the benefit of pest surveys and biodiversity studies.

Published
2022
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9. Personalizing, not patronizing: the case for patient autonomy by unbiased presentation of management options in stage I testicular cancer

Author

Oldenburg, J., Aparicio, J., Beyer, J., Cohn-Cedermark, G., Cullen, M., Gilligan, T., De Giorgi, U., De Santis, M., de Wit, R., Fosså, S. D., Germà-Lluch, J. R., Gillessen, S., Haugnes, H. S., Honecker, F., Horwich, A., Lorch, A., Ondruš, D., Rosti, G., Stephenson, A. J., Tandstad, T., Oldenburg, J., Aparicio, J., Beyer, J., Cohn-Cedermark, G., Cullen, M., Gilligan, T., De Giorgi, U., De Santis, M., de Wit, R., Fosså, S. D., Germà-Lluch, J. R., Gillessen, S., Haugnes, H. S., Honecker, F., Horwich, A., Lorch, A., Ondruš, D., Rosti, G., Stephenson, A. J., and Tandstad, T.

Abstract

Testicular cancer (TC) is the most common neoplasm in males aged 15 to 40 years and approximately 65%-75% have clinical stage I (CSI) disease. Both surveillance and adjuvant chemotherapy may be applied with indistinguishable long-term survival rates. Therefore, the patient should decide based on risk factors and potential benefits and harms rather than adopting a uniform recommendation for all

Published
2017

16. Personalizing, not patronizing: the case for patient autonomy by unbiased presentation of management options in stage I testicular cancer

Author

Oldenburg, J, Aparicio, J, Beyer, J, Cohn-Cedermark, G, Cullen, M, Gilligan, T, De Giorgi, U, De Santis, M, de Wit, R, Fosså, S D, Germà-Lluch, J R, Gillessen, S, Haugnes, H S, Honecker, F, Horwich, A, Lorch, A, Ondruš, D, Rosti, G, Stephenson, A J, Tandstad, T, Oldenburg, J, Aparicio, J, Beyer, J, Cohn-Cedermark, G, Cullen, M, Gilligan, T, De Giorgi, U, De Santis, M, de Wit, R, Fosså, S D, Germà-Lluch, J R, Gillessen, S, Haugnes, H S, Honecker, F, Horwich, A, Lorch, A, Ondruš, D, Rosti, G, Stephenson, A J, and Tandstad, T

Abstract

Testicular cancer (TC) is the most common neoplasm in males aged 15-40 years. The majority of patients have no evidence of metastases at diagnosis and thus have clinical stage I (CSI) disease [Oldenburg J, Fossa SD, Nuver J et al. Testicular seminoma and non-seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013; 24(Suppl 6): vi125-vi132; de Wit R, Fizazi K. Controversies in the management of clinical stage I testis cancer. J Clin Oncol 2006; 24: 5482-5492.]. Management of CSI TC is controversial and options include surveillance and active treatment. Different forms of adjuvant therapy exist, including either one or two cycles of carboplatin chemotherapy or radiotherapy for seminoma and either one or two cycles of cisplatin-based chemotherapy or retroperitoneal lymph node dissection for non-seminoma. Long-term disease-specific survival is ∼99% with any of these approaches, including surveillance. While surveillance allows most patients to avoid additional treatment, adjuvant therapy markedly lowers the relapse rate. Weighing the net benefits of surveillance against those of adjuvant treatment depends on prioritizing competing aims such as avoiding unnecessary treatment, avoiding more burdensome treatment with salvage chemotherapy and minimizing the anxiety, stress and life disruption associated with relapse. Unbiased information about the advantages and disadvantages of surveillance and adjuvant treatment is a prerequisite for informed consent by the patient. In a clinical scenario like CSI TC, where different disease-management options produce indistinguishable long-term survival rates, patient values, priorities and preferences should be taken into account. In this review, we provide an overview about risk factors for relapse, potential benefits and harms of adjuvant chemotherapy and active surveillance and a rationale for involving patients in individualized decision making about their treatment rather than adopting a u

Published
2015

20. Diagnosis of Lobesia botrana (Lepidoptera: Tortricidae) Using Real-Time PCR.

Author

Ledezma, L. A., Barr, N. B., Epstein, M. E., and Gilligan, T. M.

Subjects
POLYMERASE chain reaction, POLLUTANTS, INSECT identification, INSECT DNA, PESTS
Abstract

A real-time PCR assay is reported for identification of Lobesia botrana (Denis and Schiffermüller) collected in California. This assay multiplexes two independent TaqMan probe systems in a single reaction tube to reduce handling time and sample exposure to environmental contaminants. One probe system targets a segment of DNA located in the internal transcribed spacer region 2 (ITS2) that is present in the L. botrana genome but absent in native North American Tortricidae. The second probe system serves as a control for DNA quality by targeting a segment of the 18S rDNA gene that is conserved in L. botrana and all of the tested nontarget species. The assay successfully diagnosed 70 Lobesia botrana specimens and 95 nontarget specimens. No false-positive or false-negative results were observed supporting its application for identification of this pest in California. [ABSTRACT FROM AUTHOR]

Published
2016
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25. Farewell, NFDA.

Author

GILLIGAN, T SCOTT

Subjects
CONSUMER behavior, FUNERAL services, FUNERAL homes, POETS laureate
Published
2021

27. CREATING A NO-GUN ZONE.

Author

GILLIGAN, T. SCOTT

Subjects
FIREARMS owners, BUSINESS parks, PROPERTY rights, FUNERAL homes, GUN laws
Published
2020

38. Protecting Your Firm.

Author

GILLIGAN, T. SCOTT

Subjects
CASE disposition, MARRIAGE licenses, EQUAL rights
Published
2021

46. Last Responders.

Author

Gilligan, T. Scott

Subjects
CONSUMER price indexes, VETERANS' families, SICK leave
Published
2020

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