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166 results on '"Gilhuijs K"'

3. Multi-modal Volumetric Concept Activation to Explain Detection and Classification of Metastatic Prostate Cancer on PSMA-PET/CT

Author

Kraaijveld, R. C. J., Philippens, M. E. P., Eppinga, W. S. C., Jürgenliemk-Schulz, I. M., Gilhuijs, K. G. A., Kroon, P. S., van der Velden, B. H. M., Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Reyes, Mauricio, editor, Henriques Abreu, Pedro, editor, and Cardoso, Jaime, editor

Published
2022
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6. Predicting response to neoadjuvant chemotherapy with liquid biopsies and multiparametric MRI in patients with breast cancer

Author

Beeldverwerking ISI, Cancer, Epi Kanker Team C, Medisch Oncologische Disciplines, Pathologie, Speerpunt Cancer, JC onderzoeksprogramma Kanker, Janssen, L. M., Janse, M. H.A., Penning de Vries, B. B.L., van der Velden, B. H.M., Wolters-van der Ben, E. J.M., van den Bosch, S. M., Sartori, A., Jovelet, C., Agterof, M. J., Ten Bokkel Huinink, D., Bouman-Wammes, E. W., van Diest, P. J., van der Wall, E., Elias, S. G., Gilhuijs, K. G.A., Beeldverwerking ISI, Cancer, Epi Kanker Team C, Medisch Oncologische Disciplines, Pathologie, Speerpunt Cancer, JC onderzoeksprogramma Kanker, Janssen, L. M., Janse, M. H.A., Penning de Vries, B. B.L., van der Velden, B. H.M., Wolters-van der Ben, E. J.M., van den Bosch, S. M., Sartori, A., Jovelet, C., Agterof, M. J., Ten Bokkel Huinink, D., Bouman-Wammes, E. W., van Diest, P. J., van der Wall, E., Elias, S. G., and Gilhuijs, K. G.A.

Published
2024

8. MRI to assess response after neoadjuvant chemotherapy in breast cancer subtypes: a systematic review and meta-analysis

Author

Strategische Impuls RvB ISI, MS Hoofd-Hals Chirurgische Oncologie, Other research (not in main researchprogram), Onderzoek Beeld, Cancer, Beeldverwerking ISI, Pathologie, Medisch Oncologische Disciplines, Speerpunt Cancer, Epi Kanker Team C, JC onderzoeksprogramma Kanker, Janssen, L. M., den Dekker, B. M., Gilhuijs, K. G.A., van Diest, P. J., van der Wall, E., Elias, S. G., Strategische Impuls RvB ISI, MS Hoofd-Hals Chirurgische Oncologie, Other research (not in main researchprogram), Onderzoek Beeld, Cancer, Beeldverwerking ISI, Pathologie, Medisch Oncologische Disciplines, Speerpunt Cancer, Epi Kanker Team C, JC onderzoeksprogramma Kanker, Janssen, L. M., den Dekker, B. M., Gilhuijs, K. G.A., van Diest, P. J., van der Wall, E., and Elias, S. G.

Published
2022

9. Multi-modal Volumetric Concept Activation to Explain Detection and Classification of Metastatic Prostate Cancer on PSMA-PET/CT

Author

Klinische Fysica RT, Cancer, MS Radiotherapie, Beeldverwerking ISI, Reyes, Mauricio, Henriques Abreu, Pedro, Cardoso, Jaime, Kraaijveld, R. C.J., Philippens, M. E.P., Eppinga, W. S.C., Jürgenliemk-Schulz, I. M., Gilhuijs, K. G.A., Kroon, P. S., van der Velden, B. H.M., Klinische Fysica RT, Cancer, MS Radiotherapie, Beeldverwerking ISI, Reyes, Mauricio, Henriques Abreu, Pedro, Cardoso, Jaime, Kraaijveld, R. C.J., Philippens, M. E.P., Eppinga, W. S.C., Jürgenliemk-Schulz, I. M., Gilhuijs, K. G.A., Kroon, P. S., and van der Velden, B. H.M.

Published
2022

16. Perfusion in the contralateral breast on preoperative MRI may complement ER-pathway activity from the index tumor to stratify outcome of endocrine therapy for early-stage invasive breast cancer

Author

Beeldverwerking ISI, MS Reumatologie/Immunologie/Infectie, Infection & Immunity, Cancer, Van der Velden, B., Bismeijer, T., Canisius, S., Loo, C., Lips, E., Wesseling, J., Viergever, M., Wessels, L., Gilhuijs, K., Beeldverwerking ISI, MS Reumatologie/Immunologie/Infectie, Infection & Immunity, Cancer, Van der Velden, B., Bismeijer, T., Canisius, S., Loo, C., Lips, E., Wesseling, J., Viergever, M., Wessels, L., and Gilhuijs, K.

Published
2018

17. Preoperative indication for systemic therapy extended to patients with early-stage breast cancer using multiparametric 7-tesla breast MRI

Author

Schmitz, A. M. T., primary, Veldhuis, W. B., additional, Menke-Pluijmers, M. B. E., additional, van der Kemp, W. J. M., additional, van der Velden, T. A., additional, Viergever, M. A., additional, Mali, W. P. T. M., additional, Kock, M. C. J. M., additional, Westenend, P. J., additional, Klomp, D. W. J., additional, and Gilhuijs, K. G. A., additional

Published
2017
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19. Preoperative indication for systemic therapy extended to patients with early-stage breast cancer using multiparametric 7-tesla breast MRI

Author

Schmitz, A M T, Veldhuis, W B, Menke-Pluijmers, Marian B E, van der Kemp, W J M, van der Velden, T A, Viergever, M A, Mali, W P T M, Kock, Marc C J M, Westenend, Pieter J., Klomp, D W J, Gilhuijs, K G A, Schmitz, A M T, Veldhuis, W B, Menke-Pluijmers, Marian B E, van der Kemp, W J M, van der Velden, T A, Viergever, M A, Mali, W P T M, Kock, Marc C J M, Westenend, Pieter J., Klomp, D W J, and Gilhuijs, K G A

Published
2017

20. Preoperative indication for systemic therapy extended to patients with early-stage breast cancer using multiparametric 7-tesla breast MRI

Author

Arts-assistenten Radiologie, MS Radiologie, Cancer, Highfield Research Group, Beeldverwerking ISI, Schmitz, A M T, Veldhuis, W B, Menke-Pluijmers, Marian B E, van der Kemp, W J M, van der Velden, T A, Viergever, M A, Mali, W P T M, Kock, Marc C J M, Westenend, Pieter J., Klomp, D W J, Gilhuijs, K G A, Arts-assistenten Radiologie, MS Radiologie, Cancer, Highfield Research Group, Beeldverwerking ISI, Schmitz, A M T, Veldhuis, W B, Menke-Pluijmers, Marian B E, van der Kemp, W J M, van der Velden, T A, Viergever, M A, Mali, W P T M, Kock, Marc C J M, Westenend, Pieter J., Klomp, D W J, and Gilhuijs, K G A

Published
2017

23. Dual-head gamma camera system for intraoperative localization of radioactive seeds

Author

Beeldverwerking ISI, Cancer, Fysica Radiologie, Circulatory Health, Arsenali, B., De Jong, H. W A M, Viergever, M. A., Dickerscheid, D. B M, Beijst, C., Gilhuijs, K. G A, Beeldverwerking ISI, Cancer, Fysica Radiologie, Circulatory Health, Arsenali, B., De Jong, H. W A M, Viergever, M. A., Dickerscheid, D. B M, Beijst, C., and Gilhuijs, K. G A

Published
2015

25. Neoadjuvante systemische therapie bij het primair operabel mammacarcinoom: meer voordelen dan alleen borstsparende behandeling

Author

Straver, M. E., van Adrichem, J. C., Rutgers, E. J. Th, Rodenhuis, S., Linn, S. C., Loo, C. E., Gilhuijs, K. G., Oldenburg, H. S. A., Wesseling, J., Russell, N. S., Antonini, N., Vrancken Peeters, M. T. F. D., and Other departments

Subjects
skin and connective tissue diseases
Abstract

OBJECTIVE: To analyse the extent to which primary systemic therapy (PST) achieves the main goals in patients with operable primary breast cancer, these goals being breast-conserving therapy and pathological complete remission (pCR), and to evaluate the response. DESIGN: Retrospective. METHOD: In a retrospective analysis of 254 patients treated with PST in 2000-2007 in the Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, patients with inoperable disease (T4 and/or N3) were excluded. The response was mostly evaluated using contrast-enhanced MRI, whereby the chemotherapy regimen was switched if the reduction in the largest diameter of contrast washout was less than 25%. pCR was defined as no evidence of invasive cancer in the breast and axilla in the resection specimen. RESULTS: In patients with ductal carcinoma and lobular carcinoma an increase in breast-conserving therapy was seen in 32% and 17% of patients respectively. The pCR rate was 12% and 2% respectively. Secondary mastectomy because of irradical resection was required in 3% and 50% respectively. Multivariate analysis indicated that molecular type, defined on the basis of the expression of hormone receptors and human epidermal growth factor receptor 2 (HER2), i.e. luminal (oestrogen receptor-positive), basal (hormone receptor-negative and HER2-negative) and HER2-positive tumours treated with trastuzumab was the only independent predictor of pCR; 2%, 28% and 35% respectively (p=0.004). In 43 patients the chemotherapy regimen was adjusted because the tumour did not respond sufficiently. A favourable clinical response was observed in 72% (31/43) of these patients. CONCLUSION: The observed increase in the number of breast-conserving therapies after PST was clinically relevant. PST may be more effective when contrast-enhanced MRI is used for interim evaluation, based on which the treatment may be switched. There was a clear difference in histological and molecular types of tumour and therefore the choice of treatment may be adjusted accordingly

Published
2008

26. Neoadjuvant chemotherapy adaptation and serial MRI response monitoring in ER-positive HER2-negative breast cancer

Author

Rigter, L S, primary, Loo, C E, additional, Linn, S C, additional, Sonke, G S, additional, van Werkhoven, E, additional, Lips, E H, additional, Warnars, H A, additional, Doll, P K, additional, Bruining, A, additional, Mandjes, I A, additional, Vrancken Peeters, M J, additional, Wesseling, J, additional, Gilhuijs, K G, additional, and Rodenhuis, S, additional

Published
2013
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37. Automatic on-line inspection of patient setup in radiation therapy using digital portal images

Author

Van Herk, Marcel, Gilhuijs, K G, and van Herk, M

Subjects
Matching (statistics), business.industry, Computer science, Image quality, medicine.medical_treatment, Radiotherapy Planning, Computer-Assisted, Software Validation, General Medicine, Translation (geometry), Radiation therapy, Radiography, Digital image, Line (geometry), Medical imaging, medicine, Humans, Computer vision, Artificial intelligence, business, Rotation (mathematics)
Abstract

A new method is presented for inspection of patient setup in radiation therapy by automatic comparison of the patient position relative to the beam position in portal and simulator images. Quantification of patient-setup errors in terms of translation, rotation, and magnification is achieved by chamfer matching, a robust technique to match drawings and images, which is applied to both anatomy outlines and field edges. Applied to field edges, chamfer matching detects and visualizes deviations in field shape. Applied to anatomy outlines, the matching procedure quantifies and visualizes deviations in patient position relative to the radiation field. To test the method and to judge its feasibility, its behavior for four hundred different patient-setup deviations, which were simulated in four clinical images, was examined. These images show a top view of the pelvic region. The performance was measured in terms of accuracy and success rate for numerous cost functions and distance codings associated with the chamfer matching procedure. An average accuracy of 1.8 mm was found, a success rate of 90%, and an average overall computation time of 3 s on a 486 microcomputer. The whole analysis procedure is fast enough to allow on-line application.

Published
1993
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44. Automatic verification of radiation field shape using digital portal images

Author

Van Herk, Marcel, Bijhold, J, Gilhuijs, K G, and van Herk, M

Subjects
medicine.diagnostic_test, Computer science, business.industry, Radiation field, medicine.medical_treatment, Normalization (image processing), Magnification, Computed tomography, General Medicine, Visual inspection, Radiation therapy, Radiographic Image Enhancement, Radiotherapy, High-Energy, Digital image, Optics, medicine, Medical imaging, Humans, Computer vision, Irradiation, Artificial intelligence, business, Digital radiography
Abstract

Two computer methods for matching digital line drawings have been tested for automatic on-line verification of the radiation field shape during radiotherapy. This work is part of a research program aiming at automated inspection of on-line acquired digital portal images. Both methods, moment normalization and point distance minimization, compare the field edge detected in the portal image with the intended field edge and the beam shaping devices marked in the simulator image. Tests showed that the methods should be used together. First, shape deviations in the detected field edge are classified quickly, in less than a second (25 MHz 386 + 387 PC), as large (e.g., missing blocks) or small (e.g., shifts of a few mm) by moment normalization. Then the portal image is mapped to the simulator image by field edge alignment with a translation and magnification obtained from moment normalization and a rotation from point distance minimization. The mapped portal image and the simulator image juxtaposed on a monitor screen for visual inspection. Finally, the small field shape deviations are detected by an analysis of the relationship between the radiation field shape and the positioning of field shaping devices using point distance minimization.

Published
1992
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