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Topological network alignment aims to align two networks node-wise in order to maximize the observed common connection (edge) topology between them. The topological alignment of two Protein-Protein Interaction (PPI) networks should thus expose protein pairs with similar interaction partners allowing, for example, the prediction of common Gene Ontology (GO) terms. Unfortunately, no network alignment algorithm based on topology alone has been able to achieve this aim, though those that include sequence similarity have seen some success. We argue that this failure of topology alone is due to the sparsity and incompleteness of the PPI network data of almost all species, which provides the network topology with a small signal-to-noise ratio that is effectively swamped when sequence information is added to the mix. Here we show that the weak signal can be detected using multiple stochastic samples of "good" topological network alignments, which allows us to observe regions of the two networks that are robustly aligned across multiple samples. The resulting Network Alignment Frequency (NAF) strongly correlates with GO-based Resnik semantic similarity and enables the first successful cross-species predictions of GO terms based on topology-only network alignments. Our best predictions have an AUPR of about 0.4, which is competitive with state-of-the-art algorithms, even when there is no observable sequence similarity and no known homology relationship. While our results provide only a "proof of concept" on existing network data, we hypothesize that predicting GO terms from topology-only network alignments will become increasingly practical as the volume and quality of PPI network data increase., Comment: 31 pages; 9 Figures; 8 Tables

The dark colors of Jupiter's North Equatorial Belt (NEB, $7-17^\circ$N) appeared to expand northward into the neighboring zone in 2015, consistent with a 3-5 year cycle of activity in the NEB. Inversions of thermal-IR imaging from the Very Large Telescope revealed a moderate warming and reduction of aerosol opacity at the cloud tops at $17-20^\circ$N, suggesting subsidence and drying in the expanded sector. Two new thermal waves were identified during this period: (i) an upper tropospheric thermal wave (wavenumber 16-17, amplitude 2.5 K at 170 mbar) in the mid-NEB that was anti-correlated with haze reflectivity; and (ii) a stratospheric wave (wavenumber 13-14, amplitude 7.3 K at 5 mbar) at $20-30^\circ$N. Both were quasi-stationary, confined to regions of eastward zonal flow, and are morphologically similar to waves observed during previous expansion events., Comment: 28 pages, 15 figures, published in Geophysical Research Letters

The transformation of Jupiter's South Equatorial Belt (SEB) from its faded, whitened state in 2009-2010 to its normal brown appearance is documented via comparisons of thermal-infrared (5-20 $\mu$m) and visible-light imaging between November 2010 and November 2011. The SEB revival consisted of convective eruptions triggered over $\sim100$ days, potentially powered by the latent heat released by the condensation of water. The plumes rise from the water cloud base and ultimately diverge and cool in the stably-stratified upper troposphere. Thermal-IR images were acquired 2 days after the SEB disturbance was first detected by amateur observers on November 9th 2010. Subsequent images revealed the cold, putatively anticyclonic and cloudy plume tops surrounded by warm, cloud-free conditions at their peripheries. The majority of the plumes erupted from a single source near $140-160^\circ$W, coincident with the remnant cyclonic circulation of a brown barge that had formed during the fade. Additional plumes erupted from the leading edge of the central disturbance immediately east of the source. The tropospheric plumes excited stratospheric thermal waves over the SEB, showing a direct connection between moist convection and stratospheric wave activity. The subsidence of dry, unsaturated air warmed the troposphere and removed the white aerosols. The aerosol-free air was redistributed throughout the SEB by the zonal flow, following a westward-moving southern branch and an eastward-moving northern branch that revived the brown colouration over $\sim200$ days. The last stage of the revival was the re-establishment of normal convective activity northwest of the GRS in September 2011. Moist convection may therefore play an important role in controlling the timescale and atmospheric variability during the SEB life cycle. [Abridged], Comment: 30 pages, 13 figures, accepted for publication in Icarus (2017)

Global maps of Jupiter's atmospheric temperatures, gaseous composition and aerosol opacity are derived from a programme of 5-20 $\mu$m mid-infrared spectroscopic observations using the Texas Echelon Cross Echelle Spectrograph (TEXES) on NASA's Infrared Telescope Facility (IRTF). Image cubes from December 2014 in eight spectral channels, with spectral resolutions of $R\sim2000-12000$ and spatial resolutions of $2-4^\circ$ latitude, are inverted to generate 3D maps of tropospheric and stratospheric temperatures, 2D maps of upper tropospheric aerosols, phosphine and ammonia, and 2D maps of stratospheric ethane and acetylene. The results are compared to a re-analysis of Cassini Composite Infrared Spectrometer (CIRS) observations acquired during Cassini's closest approach to Jupiter in December 2000, demonstrating that this new archive of ground-based mapping spectroscopy can match and surpass the quality of previous investigations, and will permit future studies of Jupiter's evolving atmosphere. We identify mid-infrared signatures of Jupiter's 5-$\mu$m hotspots via simultaneous M, N and Q-band observations, which are interpreted as temperature and ammonia variations in the northern Equatorial Zone and on the edge of the North Equatorial Belt (NEB). Equatorial plumes enriched in NH$_3$ gas are located south-east of NH$_3$-desiccated `hotspots' on the edge of the NEB. Comparison of the hotspot locations in several channels across the 5-20 $\mu$m range indicate that these anomalous regions tilt westward with altitude. Aerosols and PH$_3$ are both enriched at the equator but are not co-located with the NH$_3$ plumes. We find hemispheric asymmetries in the distribution of tropospheric PH$_3$, stratospheric hydrocarbons and the 2D wind field. Jupiter's stratosphere is notably warmer at northern mid-latitudes than in the south in both 2000 and 2014. [Abridged], Comment: 44 pages, 21 figures, published in Icarus

The seasonal evolution of Saturn's polar atmospheric temperatures and hydrocarbon composition is derived from a decade of Cassini Composite Infrared Spectrometer (CIRS) 7-16 $\mu$m thermal infrared spectroscopy. We construct a near-continuous record of atmospheric variability poleward of 60$^\circ$ from northern winter/southern summer (2004, $L_s=293^\circ$) through the equinox (2009, $L_s=0^\circ$) to northern spring/southern autumn (2014, $L_s=56^\circ$). The hot tropospheric polar cyclones and the hexagonal shape of the north polar belt are both persistent features throughout the decade of observations. The hexagon vertices rotated westward by $\approx30^\circ$ longitude between March 2007 and April 2013, confirming that they are not stationary in the Voyager-defined System III longitude system as previously thought. The extended region of south polar stratospheric emission has cooled dramatically poleward of the sharp temperature gradient near 75$^\circ$S, coinciding with a depletion in the abundances of acetylene and ethane, and suggestive of stratospheric upwelling with vertical wind speeds of $w\approx+0.1$ mm/s. This is mirrored by a general warming of the northern polar stratosphere and an enhancement in acetylene and ethane abundances that appears to be most intense poleward of 75$^\circ$N, suggesting subsidence at $w\approx-0.15$ mm/s. However, the sharp gradient in stratospheric emission expected to form near 75$^\circ$N by northern summer solstice (2017, $L_s=90^\circ$) has not yet been observed, so we continue to await the development of a northern summer stratospheric vortex. North polar minima in tropospheric and stratospheric temperatures were detected in 2008-2010 (lagging one season, or 6-8 years, behind winter solstice); south polar maxima appear to have occurred before the start of the Cassini observations (1-2 years after summer solstice). [Abridged], Comment: Preprint of article accepted for publication in Icarus