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3. Effectiveness of Adjuvant Chemotherapy After Radical Cystectomy for Locally Advanced and/or Pelvic Lymph Node–Positive Muscle-invasive Urothelial Carcinoma of the Bladder: A Propensity Score–Weighted Competing Risks Analysis

Author

Vetterlein, Malte W., Seisen, Thomas, May, Matthias, Nuhn, Philipp, Gierth, Michael, Mayr, Roman, Fritsche, Hans-Martin, Burger, Maximilian, Novotny, Vladimir, Froehner, Michael, Wirth, Manfred P., Protzel, Chris, Hakenberg, Oliver W., Roghmann, Florian, Palisaar, Rein-Jüri, Noldus, Joachim, Pycha, Armin, Bastian, Patrick J., Trinh, Quoc-Dien, Xylinas, Evanguelos, Shariat, Shahrokh F., Rink, Michael, Chun, Felix K.-H., Dahlem, Roland, Fisch, Margit, and Aziz, Atiqullah

Published
2018
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4. Effect of Hospital and Surgeon Case Volume on Perioperative Quality of Care and Short-term Outcomes After Radical Cystectomy for Muscle-invasive Bladder Cancer: Results From a European Tertiary Care Center Cohort

Author

Bartsch, Georg, Brookman-May, Sabine, Buchner, Alexander, Durschnabel, Melanie, Ellinger, Jörg, Froehner, Michael, Georgieva, Galia, Gördük, Murat, Grimm, Marc-Oliver, Hadaschik, Boris, Haferkamp, Axel, Hakenberg, Oliver W., Hartmann, Florian, Herrmann, Edwin, Hertle, Lothar, Hohenfellner, Markus, Janetschek, Georg, Kraischits, Nicole, Krausse, Annerose, Lusuardi, Lukas, Michel, Maurice S., Moritz, Rudolf, Müller, Stefan C., Novotny, Vladimir, Nuhn, Philipp, Pahernik, Sascha, Palisaar, Rein-Jüri, Ponholzer, Anton, Protzel, Chris, Roigas, Jan, Schmid, Marianne, Schramek, Paul, Seitz, Christian, Sikic, Danijel, Stief, Christian G., Syring, Isabella, Vallo, Stefan, Wagenlehner, Florian M., Weidner, Wolfgang, Wirth, Manfred P., Vetterlein, Malte W., Meyer, Christian P., Leyh-Bannurah, Sami-Ramzi, Mayr, Roman, Gierth, Michael, Fritsche, Hans-Martin, Burger, Maximilian, Keck, Bastian, Wullich, Bernd, Martini, Thomas, Bolenz, Christian, Pycha, Armin, Hanske, Julian, Roghmann, Florian, Noldus, Joachim, Bastian, Patrick J., Gilfrich, Christian, May, Matthias, Rink, Michael, Chun, Felix K.-H., Dahlem, Roland, Fisch, Margit, and Aziz, Atiqullah

Published
2017
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5. The Use of Neoadjuvant Chemotherapy in Patients With Urothelial Carcinoma of the Bladder: Current Practice Among Clinicians

Author

Martini, Thomas, Gilfrich, Christian, Mayr, Roman, Burger, Maximilian, Pycha, Armin, Aziz, Atiqullah, Gierth, Michael, Stief, Christian G., Müller, Stefan C., Wagenlehner, Florian, Roigas, Jan, Hakenberg, Oliver W., Roghmann, Florian, Nuhn, Philipp, Wirth, Manfred, Novotny, Vladimir, Hadaschik, Boris, Grimm, Marc-Oliver, Schramek, Paul, Haferkamp, Axel, Colleselli, Daniela, Kloss, Birgit, Herrmann, Edwin, Fisch, Margit, May, Matthias, and Bolenz, Christian

Published
2017
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7. Metabolic Alkalosis

Author

Gierth, Michael, Banas, Bernhard, Burger, Maximilian, Merseburger, Axel S., editor, Kuczyk, Markus A., editor, and Moul, Judd W., editor

Published
2014
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8. Short-Term and Long-Term Morbidity after Radical Cystectomy in Patients with NMIBC and Comparison with MIBC: Identifying Risk Factors for Severe Short-Term Complications

Author

Haas, Maximilian, primary, Knobloch, Charlotte, additional, Mayr, Roman, additional, Gierth, Michael, additional, Pickl, Christoph, additional, Engelmann, Simon, additional, Denzinger, Stefan, additional, Burger, Maximilian, additional, Breyer, Johannes, additional, and Holbach, Sonja, additional

Published
2023
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9. Comparative analysis of comorbidity and performance indices for prediction of oncological outcomes in patients with upper tract urothelial carcinoma who were treated with radical nephroureterectomy

Author

Aziz, Atiqullah, Fritsche, Hans-Martin, Gakis, Georgios, Kluth, Luis A., al-Sayed Hassan, Fahmy, Engel, Oliver, Dahlem, Roland, Otto, Wolfgang, Gierth, Michael, Denzinger, Stefan, Schwentner, Christian, Stenzl, Arnulf, Shariat, Shahrokh F., Fisch, Margit, Burger, Maximilian, and Rink, Michael

Published
2014
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10. Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: results from PROMETRICS 2011

Author

May, Matthias, Fritsche, Hans-Martin, Vetterlein, Malte W., Bastian, Patrick J., Gierth, Michael, Nuhn, Philipp, Aziz, Atiqullah, Fisch, Margit, Stief, Christian G., Hohenfellner, Markus, Wirth, Manfred P., Novotny, Vladimir, Hakenberg, Oliver W., Noldus, Joachim, Gilfrich, Christian, Bolenz, Christian, Burger, Maximilian, Brookman-May, Sabine D., Bartsch, G, Bolenz, C, Buchner, A, Chun, FK, Dahlem, R, Durschnabel, M, Ellinger, J, Froehner, M, Georgieva, G, Gördük, M, Grimm, MO, Grimm, T, Hadaschik, B, Haferkamp, A, Hartmann, F, Herrmann, E, Janetschek, G, Karl, A, Keck, B, Kraischits, N, Krausse, A, Lusuardi, L, Martini, T, Mayr, R, Michel, MS, Moritz, R, Müller, SC, Nuhn, P, Pahernik, S, Palisaar, RJ, Ponholzer, A, Protzel, C, Pycha, A, Rink, M, Roghmann, F, Roigas, J, Schmid, M, Schramek, P, Seitz, C, Shariat, SF, Sikic, D, Syring, I, Vallo, S, Wagenlehner, FM, Wullich, B, and PROMETRICS 2011 Research Group

Published
2017
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12. Peri‐operative allogeneic blood transfusion does not adversely affect oncological outcomes after radical cystectomy for urinary bladder cancer: a propensity score‐weighted European multicentre study

Author

Vetterlein, Malte W., Gild, Philipp, Kluth, Luis A., Seisen, Thomas, Gierth, Michael, Fritsche, Hans‐Martin, Burger, Maximilian, Protzel, Chris, Hakenberg, Oliver W., von Landenberg, Nicolas, Roghmann, Florian, Noldus, Joachim, Nuhn, Philipp, Pycha, Armin, Rink, Michael, Chun, Felix K.‐H., May, Matthias, Fisch, Margit, Aziz, Atiqullah, Bartsch, G, Bolenz, C, Brookman‐May, S, Buchner, A, Durschnabel, M, Ellinger, J, Froehner, M, Georgieva, G, Gilfrich, C, Gördük, M, Grimm, MO, Hadaschik, B, Haferkamp, A, Hartmann, F, Herrmann, E, Hertle, L, Hohenfellner, M, Janetschek, G, Keck, B, Kraischits, N, Krausse, A, Lusuardi, L, Martini, T, Michel, MS, Moritz, R, Müller, SC, Novotny, V, Pahernik, S, Palisaar, RJ, Ponholzer, A, Roigas, J, Schmid, M, Schramek, P, Seitz, C, Sikic, D, Stief, CG, Syring, I, Traumann, M, Vallo, S, Wagenlehner, FM, Weidner, W, Wirth, MP, and Wullich, B

Published
2018
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13. Effect of Hospital and Surgeon Case Volume on Perioperative Quality of Care and Short-term Outcomes After Radical Cystectomy for Muscle-invasive Bladder Cancer: Results From a European Tertiary Care Center Cohort

Author

Vetterlein, Malte W., Meyer, Christian P., Leyh-Bannurah, Sami-Ramzi, Mayr, Roman, Gierth, Michael, Fritsche, Hans-Martin, Burger, Maximilian, Keck, Bastian, Wullich, Bernd, Martini, Thomas, Bolenz, Christian, Pycha, Armin, Hanske, Julian, Roghmann, Florian, Noldus, Joachim, Bastian, Patrick J., Gilfrich, Christian, May, Matthias, Rink, Michael, Chun, Felix K.-H., Dahlem, Roland, Fisch, Margit, and Aziz, Atiqullah

Published
2017
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14. Analysis of Sex Differences in Cancer-Specific Survival and Perioperative Mortality Following Radical Cystectomy: Results of a Large German Multicenter Study of Nearly 2500 Patients with Urothelial Carcinoma of the Bladder

Author

Otto, Wolfgang, May, Matthias, Fritsche, Hans-Martin, Dragun, Duska, Aziz, Atiqullah, Gierth, Michael, Trojan, Lutz, Herrmann, Edwin, Moritz, Rudolf, Ellinger, Jörg, Tilki, Derya, Buchner, Alexander, Höfner, Thomas, Brookman-May, Sabine, Nuhn, Philipp, Gilfrich, Christian, Roigas, Jan, Zacharias, Mario, Denzinger, Stefan, Hohenfellner, Markus, Haferkamp, Axel, Müller, Stefan C., Kocot, Arkadius, Riedmiller, Hubertus, Wieland, Wolf F., Stief, Christian G., Bastian, Patrick J., and Burger, Maximilian

Published
2012
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15. Optimizing outcome reporting after radical cystectomy for organ-confined urothelial carcinoma of the bladder using oncological trifecta and pentafecta

Author

Aziz, Atiqullah, Gierth, Michael, Rink, Michael, Schmid, Marianne, Chun, Felix K., Dahlem, Roland, Roghmann, Florian, Palisaar, Rein-Jüri, Noldus, Joachim, Ellinger, Jörg, Müller, Stefan C., Pycha, Armin, Martini, Thomas, Bolenz, Christian, Moritz, Rudolf, Herrmann, Edwin, Keck, Bastian, Wullich, Bernd, Mayr, Roman, Fritsche, Hans-Martin, Burger, Maximilian, Bastian, Patrick J., Seitz, Christian, Brookman-May, Sabine, Xylinas, Evanguelos, Shariat, Shahrokh F., Fisch, Margit, May, Matthias, and the PROMETRICS 2011 Research Group

Published
2015
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16. Risk stratification for locoregional recurrence after radical cystectomy for urothelial carcinoma of the bladder

Author

Novotny, Vladimir, Froehner, Michael, May, Matthias, Protzel, Chris, Hergenröther, Katrin, Rink, Michael, Chun, Felix K., Fisch, Margit, Roghmann, Florian, Palisaar, Rein-Jüri, Noldus, Joachim, Gierth, Michael, Fritsche, Hans-Martin, Burger, Maximilian, Sikic, Danijel, Keck, Bastian, Wullich, Bernd, Nuhn, Philipp, Buchner, Alexander, Stief, Christian G., Vallo, Stefan, Bartsch, Georg, Haferkamp, Axel, Bastian, Patrick J., Hakenberg, Oliver W., Propping, Stefan, and Aziz, Atiqullah

Published
2015
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18. Evidence from the ‘PROspective MulticEnTer RadIcal Cystectomy Series 2011 (PROMETRICS 2011)’ Study: How are Preoperative Patient Characteristics Associated with Urinary Diversion Type After Radical Cystectomy for Bladder Cancer?

Author

Schmid, Marianne, Rink, Michael, Traumann, Miriam, Bastian, Patrick J., Bartsch, Georg, Ellinger, Jörg, Grimm, Marc-Oliver, Hadaschik, Boris, Haferkamp, Axel, Hakenberg, Oliver W., Aziz, Atiqullah, Hartmann, Florian, Herrmann, Edwin, Hohenfellner, Markus, Janetschek, Günter, Gierth, Michael, Pahernik, Sasc ha, Protzel, Chris, Roigas, Jan, Gördük, Murat, Lusuardi, Lukas, May, Matthias, Trinh, Quoc-Dien, Fisch, Margit, Chun, Felix K.H., and PROMETRICS 2011 Research Group

Published
2015
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19. A Phase 1/2 Single-arm Clinical Trial of Recombinant Bacillus Calmette-Guérin (BCG) VPM1002BC Immunotherapy in Non–muscle-invasive Bladder Cancer Recurrence After Conventional BCG Therapy: SAKK 06/14

Author

Rentsch, Cyrill A., primary, Thalmann, George N., additional, Lucca, Ilaria, additional, Kwiatkowski, Maciej, additional, Wirth, Grégory J., additional, Strebel, Räto T., additional, Engeler, Daniel, additional, Pedrazzini, Augusto, additional, Hüttenbrink, Clemens, additional, Schultze-Seemann, Wolfgang, additional, Torpai, Raimund, additional, Bubendorf, Lukas, additional, Wicki, Andreas, additional, Roth, Beat, additional, Bosshard, Piet, additional, Püschel, Heike, additional, Boll, Daniel T., additional, Hefermehl, Lukas, additional, Roghmann, Florian, additional, Gierth, Michael, additional, Ribi, Karin, additional, Schäfer, Simon, additional, and Hayoz, Stefanie, additional

Published
2022
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20. EXTRACAPSULAR EXTENSION AND LYMPH NODE DENSITY IN UROTHELIAL CARCINOMA OF THE BLADDER FOLLOWING RADICAL CYSTECTOMY IN NODAL-POSITIVE PATIENTS: MP38-15

Author

Aziz, Atiqullah, Nuhn, Philipp, Gierth, Michael, Novotny, Vladimir, Roghmann, Florian, May, Matthias, Tilki, Derya, Rink, Michael, Mayr, Roman, Fritsche, Hans-Martin, Burger, Maximilian, Pycha, Armin, Froehner, Michael, Wirth, Manfred P., Protzel, Chris, Hakenberg, Oliver W., Palisaar, Rein-Jüri, Noldus, Joachim, Vallo, Stefan, Bartsch, Georg, Haferkamp, Axel, Bastian, Patrick J., Gilfrich, Christian, Dahlem, Roland, Fisch, Margit, and Chun, Felix

Published
2016
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21. HOSPITAL BUT NOT SURGICAL VOLUME PREDICTS 30- AND 90-DAY COMPLICATIONS IN RADICAL CYSTECTOMY (RC) – RESULTS FROM THE PROSPECTIVE MULTICENTER RADICAL CYSTECTOMY SERIES (PROMETRICS 2011) STUDY GROUP: PD02-04

Author

Meyer, Christian, Ley-Bannurah, Sami-Ramzi, Vetterlein, Malte, Mayr, Roman, Gierth, Michael, Fritsche, Hans-Martin, Burger, Maximilian, Keck, Bastian, Wullich, Bernd, Martini, Thomas, Bolenz, Christian, Pycha, Armin, Hanske, Julian, Roghman, Florian, Noldus, Joachim, Gilfrich, Christian, May, Matthias, Bastian, Patrick, Rink, Michael, Chun, Felix, Dahlem, Roland, Fisch, Margit, and Aziz, Atiqullah

Published
2016
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22. MP58-16 PREDICTION OF CANCER-SPECIFIC SURVIVAL IN PATIENTS WITH RADICAL CYSTECTOMY FOR BLADDER CANCER USING ARTIFICIAL NEURAL NETWORKS

Author

Nuhn, Philipp, Aziz, Atiqullah, May, Matthias, Staehler, Michael, Gierth, Michael, Ellinger, Jörg, Müller, Stefan C., Wagenlehner, Florian, Weidner, Wolfgang, Moritz, Rudolf, Herrmann, Edwin, Hartmann, Florian, Grimm, Marc-Oliver, Protzel, Chris, Hakenberg, Oliver, Lusuardi, Lukas, Janetschek, Günter, Gördük, Murat, Roigas, Jan, Burger, Maximilian, Fisch, Margit, Stief, Christian G., Bastian, Patrick, Grimm, Tobias, and Buchner, Alexander

Published
2015
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25. DO PREOPERATIVE PATIENT CHARACTERISTICS INFLUENCE URINARY DIVERSION AFTER RADICAL CYSTECTOMY FOR BLADDER CANCER? – RESULTS OF THE GERMAN PROMETRICS 2011 STUDY: MP61-12

Author

Schmid, Marianne, Aziz, Atiqulla, May, Matthias, Burger, Maximilian, Palisaar, Rein-Jüri, Trinh, Quoc-Dien, Fritsche, Hans-Martin, Martini, Thomas, Bolenz, Christian, Mayr, Roman, Pycha, Armin, Nuhn, Philip, Stief, Christian, Novotny, Vladimir, Wirth, Manfred, Seitz, Christian, Noldus, Joachim, Gilfrich, Christian, Shariat, Shahrokh F., Brookman-May, Sabine, Bastian, Patrick J., Denzinger, Stefan, Gierth, Michael, Roghmann, Florian, Fisch, Margit, Chun, Felix K-H., and Rink, Michael

Published
2014
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27. Prognostic Role of mRNA-Expression of Aquaporins (AQP) 3, 4, 7 and 9 in Stage pT1 Non-Muscle-Invasive Bladder Cancer

Author

Reiß, Julian, primary, Kälble, Sebastian, additional, Bründl, Johannes, additional, Rosenhammer, Bernd, additional, Gierth, Michael, additional, Weber, Florian, additional, Eckstein, Markus, additional, Wirtz, Ralph Markus, additional, Denzinger, Stefan, additional, Burger, Maximilian, additional, Otto, Wolfgang, additional, and Breyer, Johannes, additional

Published
2021
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30. Eisenstatuserhebung vor radikaler Zystektomie beim Urothelkarzinom der Harnblase

Author

Pickl, Christoph, Haas, Maximilian, Huber, Toni, Haider, Maximilian, Gierth, Michael, Breyer, Johannes, Burger, Maximilian, and Mayr, Roman

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Die radikale Zystektomie beim Harnblasenkarzinom geht nicht selten mit einem relevanten Blutverlust und folglich peri-und postoperativer Transfusionsnotwendigkeit einher. Dies ist nicht nur mit immensen Kosten und hohem Aufwand im klinischen Alltag verbunden, Studien konnten bereits eine Korrelation[zum vollständigen Text gelangen Sie über die oben angegebene URL], 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung

Published
2019

31. Die Komplikationen der radikalen Zystektomie mit Harnableitung: Eine retrospektive, monozentrische Studie

Author

Haas, Maximilian, Siebertz, Leopold, Huber, Toni, Pickl, Christoph, Gierth, Michael, Breyer, Johannes, Burger, Maximilian, and Mayr, Roman

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die radikale Zystektomie ist eine Operation, die aufgrund des ausgedehnten chirurgischen Eingriffes und einer aggressiven Grunderkrankung mit einem hohen Risiko für Komplikationen vergesellschaftet ist. Ziel dieser Studie war es, die Komplikationen der radikalen Zystektomie objektiv,[zum vollständigen Text gelangen Sie über die oben angegebene URL], 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung

Published
2019

32. Results of a phase I/II single arm clinical trial assessing efficacy, safety and tolerability of the recombinant Bacillus Calmette Guérin VPM1002BC in patients with non-muscle invasive bladder cancer recurrence after BCG induction with or without BCG maintenance therapy – SAKK 06/14

Author

Bubendorf Lukas, Cyrill A. Rentsch, Pedrazzini Augusto, Torpai Raimund, Hefermehl Lukas, Engeler Daniel, Roghmann Florian, Boll Daniel, Bosshard Piet, Maciej Kwiatkowski, Schultze-Seemann Wolfgang, Räto T. Strebel, Grégory Johann Wirth, Hayoz Stefanie, Püschel Heike, Roth Beat, Wicki Andreas, Hüttenbrink Clemens, Gierth Michael, Ribi Karin, George N. Thalmann, Schäfer Simon, and Ilaria Lucca

Subjects
medicine.medical_specialty, Bladder cancer, business.industry, Urology, Standard treatment, Carcinoma in situ, medicine.disease, Gastroenterology, Regimen, Oncology, Tolerability, Maintenance therapy, Internal medicine, Clinical endpoint, Medicine, business, Adverse effect
Abstract

Introduction VPM1002BC is a genetically modified Mycobacterium bovis Bacillus Calmette Guerin (BCG) strain with potentially improved immunogenicity and attenuation. Here, we report on efficacy, safety and tolerability of intravesical VPM1002BC for the treatment of non-muscle invasive bladder cancer (NMIBC). Methods We designed a phase I/II single arm trial (NCT02371447). Patients were eligible with BCG failure (2008 EAU definition) and intermediate to high risk for NMIBC progression after conventional BCG therapy. The primary endpoint of the phase II part was defined as recurrence free survival (RFS) in the bladder 60 weeks after the first VPM1002BC instillation. From September 2015 to April 2018, a total of 40 patients (6 from phase I and 34 from phase II) were included into the trial. Patients were scheduled for a standard treatment of 6 weekly instillations with VPM1002BC followed by a maintenance regimen of 1 year. Results The study population consisted of 4 female and 36 male patients (median age 72 years). Previous maintenance BCG therapy was conducted in 14/40 patients. All recurrent tumours were high grade (2004 WHO definition) and 27 (67.5%) patients presented with carcinoma in situ (CIS). RFS in the bladder at 60 weeks after the first instillation was 49.3 % [95% CI 32.1%, 64.4%]. At the same time, progression in stage, grade or new occurrence of CIS had occurred in 12 (30%) patients, 3 of which had progression to muscle-invasive disease. Two patients died from bladder cancer (> 60 weeks after start of therapy). Over the whole course of therapy, treatment related grade 1, 2 and 3 AEs were observed in 15%, 52.5%, and 5% of the patients, respectively. No adverse events (AEs) grade ≥4 occurred. Two (5%) out of the 40 patients did not tolerate ≥ 5 instillations during induction. Fifteen patients (37.5%) received all scheduled instillations. Conclusion One year after start of treatment, therapy with VPM100BC resulted in freedom from NMIBC recurrence in the bladder in almost half of the patients with recurrence after previous BCG exposure. The treatment is safe and well tolerated.

Published
2020
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33. Strong Expression of Cancertestis Antigens CTAG1B and MAGEA3 Is Correlated with Unfavourable Histopathological Features and MAGEA3 Is Associated with Worse Progression-Free Survival in Urothelial Bladder Cancer

Author

Lausenmeyer, Eva Maria, primary, Braun, Klara, additional, Breyer, Johannes, additional, Gierth, Michael, additional, Denzinger, Stefan, additional, Burger, Maximilian, additional, Voelker, Hans-Ullrich, additional, and Otto, Wolfgang, additional

Published
2018
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35. Sarcopenia as a comorbidity-independent predictor of survival following radical cystectomy for bladder cancer

Author

Mayr, Roman, primary, Gierth, Michael, additional, Zeman, Florian, additional, Reiffen, Marieke, additional, Seeger, Philipp, additional, Wezel, Felix, additional, Pycha, Armin, additional, Comploj, Evi, additional, Bonatti, Matteo, additional, Ritter, Manuel, additional, van Rhijn, Bas W.G., additional, Burger, Maximilian, additional, Bolenz, Christian, additional, Fritsche, Hans-Martin, additional, and Martini, Thomas, additional

Published
2018
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36. Influence of Body Mass Index on Clinical Outcome Parameters, Complication Rate and Survival after Radical Cystectomy: Evidence from a Prospective European Multicentre Study

Author

Gierth, Michael, primary, Zeman, Florian, additional, Denzinger, Stefan, additional, Vetterlein, Malte W., additional, Fisch, Margit, additional, Bastian, Patrick J., additional, Syring, Isabella, additional, Ellinger, Jörg, additional, Müller, Stephan C., additional, Herrmann, Edwin, additional, Gilfrich, Christian, additional, May, Matthias, additional, Pycha, Armin, additional, Wagenlehner, Florian M., additional, Vallo, Stefan, additional, Bartsch, Georg, additional, Haferkamp, Axel, additional, Grimm, Marc-Oliver, additional, Roigas, Jan, additional, Protzel, Chris, additional, Hakenberg, Oliver W., additional, Fritsche, Hans-Martin, additional, Burger, Maximilian, additional, Aziz, Atiqullah, additional, and Mayr, Roman, additional

Published
2018
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37. Klinische und pathologische Prognosefaktoren für das Langzeitüberleben von Patienten mit pT1 Nierenzellkarzinom

Author

Breyer, Johannes, additional, Otto, Wolfgang, additional, Lausenmeyer, Eva, additional, Denzinger, Stefan, additional, Schwientek, Ann-Kathrin, additional, Ochs, Ludwig, additional, Mayr, Roman, additional, Gierth, Michael, additional, Bründl, Johannes, additional, Burger, Maximilian, additional, Evert, Matthias, additional, Fritsche, Hans-Martin, additional, and Eichelberg, Christian, additional

Published
2017
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38. PD36-08 PERIOPERATIVE ALLOGENEIC BLOOD TRANSFUSION DOES NOT ADVERSELY IMPACT SURVIVAL AFTER RADICAL CYSTECTOMY FOR URINARY BLADDER CANCER - A COMPETING-RISKS ANALYSIS FROM A MULTI-INSTITUTIONAL EUROPEAN SERIES

Author

Vetterlein, Malte W., primary, Gild, Philipp, additional, Kluth, Luis A., additional, Gierth, Michael, additional, Fritsche, Hans-Martin, additional, Burger, Maximilian, additional, Protzel, Chris, additional, Hakenberg, Oliver, additional, von Landenberg, Nicolas, additional, Roghmann, Florian, additional, Noldus, Joachim, additional, Nuhn, Philipp, additional, Rink, Michael, additional, Chun, Felix K.H., additional, May, Matthias, additional, Fisch, Margit, additional, and Aziz, Atiqullah, additional

Published
2017
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39. PD02-04 HOSPITAL BUT NOT SURGICAL VOLUME PREDICTS 30- AND 90-DAY COMPLICATIONS IN RADICAL CYSTECTOMY (RC) – RESULTS FROM THE PROSPECTIVE MULTICENTER RADICAL CYSTECTOMY SERIES (PROMETRICS 2011) STUDY GROUP

Author

Meyer, Christian, primary, Ley-Bannurah, Sami-Ramzi, additional, Vetterlein, Malte, additional, Mayr, Roman, additional, Gierth, Michael, additional, Fritsche, Hans-Martin, additional, Burger, Maximilian, additional, Keck, Bastian, additional, Wullich, Bernd, additional, Martini, Thomas, additional, Bolenz, Christian, additional, Pycha, Armin, additional, Hanske, Julian, additional, Roghman, Florian, additional, Noldus, Joachim, additional, Gilfrich, Christian, additional, May, Matthias, additional, Bastian, Patrick, additional, Rink, Michael, additional, Chun, Felix, additional, Dahlem, Roland, additional, Fisch, Margit, additional, and Aziz, Atiqullah, additional

Published
2016
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40. MP38-15 EXTRACAPSULAR EXTENSION AND LYMPH NODE DENSITY IN UROTHELIAL CARCINOMA OF THE BLADDER FOLLOWING RADICAL CYSTECTOMY IN NODAL-POSITIVE PATIENTS

Author

Aziz, Atiqullah, primary, Nuhn, Philipp, additional, Gierth, Michael, additional, Novotny, Vladimir, additional, Roghmann, Florian, additional, May, Matthias, additional, Tilki, Derya, additional, Rink, Michael, additional, Mayr, Roman, additional, Fritsche, Hans-Martin, additional, Burger, Maximilian, additional, Pycha, Armin, additional, Froehner, Michael, additional, Wirth, Manfred P., additional, Protzel, Chris, additional, Hakenberg, Oliver W., additional, Palisaar, Rein-Jüri, additional, Noldus, Joachim, additional, Vallo, Stefan, additional, Bartsch, Georg, additional, Haferkamp, Axel, additional, Bastian, Patrick J., additional, Gilfrich, Christian, additional, Dahlem, Roland, additional, Fisch, Margit, additional, and Chun, Felix, additional

Published
2016
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41. Strong Expression of Cancertestis Antigens CTAG1B and MAGEA3 Is Correlated with Unfavourable Histopathological Features and MAGEA3 Is Associated with Worse Progression-Free Survival in Urothelial Bladder Cancer.

Author

Lausenmeyer, Eva Maria, Braun, Klara, Breyer, Johannes, Gierth, Michael, Denzinger, Stefan, Burger, Maximilian, Voelker, Hans-Ullrich, and Otto, Wolfgang

Subjects
ANTIGENS, CANCER invasiveness, HISTOPATHOLOGY, BLADDER cancer, RETROSPECTIVE studies, IMMUNOHISTOCHEMISTRY, FOLLOW-up studies (Medicine)
Abstract

Background: Cancer/testis antigens (CTA) are expressed in urothelial bladder cancer (UBC). Their therapeutical and prognostic relevance remains unclear. We studied the correlation of MAGEA3 and CTAG1B with histopathological factors in UBC and their prognostic value. Methods: Retrospective analysis of 93 patients who underwent treatment for UBC was conducted. Besides clinical and histopathological parameters, the expression of MAGEA3 and CTAG1B was assessed by immunohistochemistry. Results: Median follow-up was 75 months. Fifteen per cent of patients showed strong positive reaction to MAGEA3 staining. These tumours were statistically and significantly more often correlated with unfavourable World Health Organization (WHO) grading (G1: 0%, G2: 10.3%, G3: 23.4%, p = 0.048; low grade 0%, high grade 18.4%, p = 0.046 respectively). Correlation of CTAG1B with WHO grading was impressive with strong expression in no G1, 31.1% of G2 and 51.1% of G3 tumours (low grade 0%, high grade 43.4%, p = 0.001, respectively). Concomitant carcinoma in situ (Cis) was associated with strong CTAG1B expression (54.2% in concomitant Cis vs. 29% without concomitant Cis, p = 0.026). Kaplan-Meier analysis revealed statistically and significantly worse 5 years progression-free survival (PFS) associated with a strong expression of MAGEA3 (59 vs. 84%, p = 0.032). Conclusions: Strong CTA expression was correlated with unfavourable histopathological features. A strong expression of MAGEA3 was statistically and significantly associated with worse PFS across all stages of UBC. [ABSTRACT FROM AUTHOR]

Published
2019
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44. Prediction of Locally Advanced Urothelial Carcinoma of the Bladder Using Clinical Parameters before Radical Cystectomy - A Prospective Multicenter Study

Author

Martini, Thomas, primary, Aziz, Atiqullah, additional, Roghmann, Florian, additional, Rink, Michael, additional, Chun, Felix K., additional, Fisch, Margit, additional, Trojan, Lutz, additional, Hakenberg, Oliver W., additional, Zastrow, Stefan, additional, Wirth, Manfred P., additional, Moersdorf, Johannes, additional, Brookman-May, Sabine, additional, Stief, Christian G., additional, Haferkamp, Axel, additional, Wagenlehner, Florian, additional, Hohenfellner, Markus, additional, Herrmann, Edwin, additional, Lusuardi, Lukas, additional, Grimm, Marc-Oliver, additional, Müller, Stephan C., additional, Roigas, Jan, additional, Bastian, Patrick J., additional, Gierth, Michael, additional, Burger, Maximilian, additional, Pycha, Armin, additional, Seitz, Christian, additional, May, Matthias, additional, and Bolenz, Christian, additional

Published
2015
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45. Matched-pair analysis of renal function in the immediate postoperative period: a comparison of living kidney donors versus patients nephrectomized for renal cell cancer

Author

Vergho, Daniel, primary, Burger, Maximilian, additional, Schrammel, Moritz, additional, Brookman-May, Sabine, additional, Gierth, Michael, additional, Hoschke, Bernd, additional, Lopau, Kai, additional, Gilfrich, Christian, additional, Riedmiller, Hubertus, additional, Wolff, Ingmar, additional, and May, Matthias, additional

Published
2014
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47. Comparative Analysis of Gender-Related Differences in Symptoms and Referral Patterns prior to Initial Diagnosis of Urothelial Carcinoma of the Bladder: A Prospective Cohort Study

Author

Aziz, Atiqullah, primary, Madersbacher, Stephan, additional, Otto, Wolfgang, additional, Mayr, Roman, additional, Comploj, Evi, additional, Pycha, Armin, additional, Denzinger, Stefan, additional, Fritsche, Hans-Martin, additional, Burger, Maximilian, additional, and Gierth, Michael, additional

Published
2014
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48. Prediction of 90-day Mortality After Radical Cystectomy for Bladder Cancer in a Prospective European Multicenter Cohort

Author

Aziz, Atiqullah, primary, May, Matthias, additional, Burger, Maximilian, additional, Palisaar, Rein-Jüri, additional, Trinh, Quoc-Dien, additional, Fritsche, Hans-Martin, additional, Rink, Michael, additional, Chun, Felix, additional, Martini, Thomas, additional, Bolenz, Christian, additional, Mayr, Roman, additional, Pycha, Armin, additional, Nuhn, Philipp, additional, Stief, Christian, additional, Novotny, Vladimir, additional, Wirth, Manfred, additional, Seitz, Christian, additional, Noldus, Joachim, additional, Gilfrich, Christian, additional, Shariat, Shahrokh F., additional, Brookman-May, Sabine, additional, Bastian, Patrick J., additional, Denzinger, Stefan, additional, Gierth, Michael, additional, and Roghmann, Florian, additional

Published
2014
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49. MP61-12 DO PREOPERATIVE PATIENT CHARACTERISTICS INFLUENCE URINARY DIVERSION AFTER RADICAL CYSTECTOMY FOR BLADDER CANCER? – RESULTS OF THE GERMAN PROMETRICS 2011 STUDY

Author

Schmid, Marianne, primary, Aziz, Atiqulla, additional, May, Matthias, additional, Burger, Maximilian, additional, Palisaar, Rein-Jüri, additional, Trinh, Quoc-Dien, additional, Fritsche, Hans-Martin, additional, Martini, Thomas, additional, Bolenz, Christian, additional, Mayr, Roman, additional, Pycha, Armin, additional, Nuhn, Philip, additional, Stief, Christian, additional, Novotny, Vladimir, additional, Wirth, Manfred, additional, Seitz, Christian, additional, Noldus, Joachim, additional, Gilfrich, Christian, additional, Shariat, Shahrokh F., additional, Brookman-May, Sabine, additional, Bastian, Patrick J., additional, Denzinger, Stefan, additional, Gierth, Michael, additional, Roghmann, Florian, additional, Fisch, Margit, additional, Chun, Felix K-H., additional, and Rink, Michael, additional

Published
2014
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50. The Charlson Comorbidity Index Predicts Survival after Disease Recurrence in Patients following Radical Cystectomy for Urothelial Carcinoma of the Bladder

Author

Mayr, Roman, primary, May, Matthias, additional, Burger, Maximilian, additional, Martini, Thomas, additional, Pycha, Armin, additional, Dechet, Christopher, additional, Lodde, Michele, additional, Comploj, Evi, additional, Wieland, Wolf F., additional, Denzinger, Stefan, additional, Otto, Wolfgang, additional, Aziz, Atiqullah, additional, Fritsche, Hans-Martin, additional, and Gierth, Michael, additional

Published
2014
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