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2. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

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Sartelli, M., Kluger, Y., Ansaloni, L., Carlet, J., Brink, A., Hardcastle, T. C., Khanna, A., Chicom-Mefire, A., Rodríguez-Baño, J., Nathwani, D., Mendelson, M., Watkins, R. R., Pulcini, C., Beović, B., May, A. K., Itani, K. M. F., Mazuski, J. E., Fry, D. E., Coccolini, F., Rasxa, K., Montravers, P., Eckmann, C., Abbo, L. M., Abubakar, S., Abu-Zidan, F. M., Adesunkanmi, A. K., Al-Hasan, M. N., Althani, A. A., Ticas, J. E. A., Ansari, S., Ansumana, R., Da Silva, A. R. A. , Augustin, G. , Bala, M. , Balogh, Z. J. , Baraket, O. , Bassetti, M. , Bellanova, G. , Beltran, M. A. , Ben-Ishay, O. , Boermeester, M. A. , Brecher, S. M. , Bueno, J. , Cainzos, M. A. , Cairns, K. , Camacho-Ortiz, A. , Ceresoli, M. , Chandy, S. J. , Cherry-Bukowiec, J. R. , Cirocchi, R. , Colak, E. , Corcione, A. , Cornely, O. A. , Cortese, F. , Cui, Y. , Curcio, D. , Damaskos, D. , Dasx, K. , Delibegovic, S. , Demetrashvili, Z. be, De Simone, B. bf, De Souza, H. P. bg, De Waele, J. bh, Dhingra, S. bi, Diaz, J. J. bj, Di Carlo, I. bk, Di Marzo, F. bl, DI TOMASO, SAVERIO, S. , Dogjani, A. , Dorj, G. , Dortet, L. , Duane, T. M. , Dupont, H. , Egiev, V. N. , Eid, H. O. , Elmangory, El-Sayed Marei, H. , Enani, M. A. , Escandón-Vargas, K. , Faro, M. P. , J.r., Ferrada, P., Foghetti, D., Foianini, E., Fraga, G. P., Frattima, S., Gandhi, C., Gattuso, G., Giamarellou, E., Ghnnam, W., Gkiokas, G., Girardis, M., Goff, D. A., Gomes, C. A., Gomi, H., Gronerth, R. I. G., Guirao, X., Guzman-Blanco, M., Haque, M., Hecker, A., Hell, M., Herzog, T., Hicks, L., Kafka-Ritsch, R., Kao, L. S., Kanj, S. S., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kashuk, J., Kenig, J., Khamis, F., Khokha, V., Kiguba, R., Kirkpatrick, A. W., Kørner, H., Koike, K., Kok, K. Y. Y., Kon, K., Kong, V., Inaba, K., Ioannidis, O., Isik, A., Iskandar, K., Labbate, M., Labricciosa, F. M., Lagrou, K., Lagunes, L., Latifi, R., Lasithiotakis, K., Laxminarayan, R., Lee, J. G., Leone, M., Leppäniemi, A., Li, Y., Liang, S. Y., Liau, K. -.H., Litvin, A., Loho, T., Lowman, W., Machain, G. Mf, Maier, R. V., Manzano-Nunez, R., Marinis, A., Marmorale, C., Martin-Loeches, I., Marwah, S., Maseda, E., McFarlane, M., BEZERRA DE MELO PEREIRA NUNES, CINTIA, R. , Melotti, R. , Memish, Z. , Mertz, D. , Mesina, C. , Menichetti, F. , Mishra, S. K. , Montori, G. , Moore, E. E. , Moore, F. A. , Naidoo, NAPOLITANO, NELLO, L. , Negoi, I. , Nicolau, D. P. , Nikolopoulos, I. , Nord, C. E. , Ofori-Asenso, R. , Olaoye, I. , Omari, A. H. , Ordoñez, C. A. , Ouadii, M. , Ouedraogo, A. , Pagani, L. , Paiva, J. A. , Parreira, J. G. , Pata, F. fm, Pereira, J., Pereira, N. R., Petrosillo, N., Picetti, E., Pintar, T., Ponce-De-Leon, A., Popovski, Z., Poulakou, G., Preller, J., Guerrero, A. P., Pupelis, G., Quiodettis, M., Rawson, T. M., Reichert, M., Reinhart, K., Rems, M., Rello, J., Rizoli, S., ROBERTS, HENRI JOHAN EDUARD, Rubio-Perez, I., Ruppé, E., Sakakushev, B., Sall, I., Kafil, H. S. j, Sanders, J., Sato, N., Sawyer, R. G., T. , Scibé, R. , Scudeller, L. , Lohse, H. S. , Sganga, G. , Shafiq, N. , Shah, J. N. , Spigaglia, P. , Suroowan, S. , Tsioutis, C. , Sifri, C. D. , Siribumrungwong, B. , Sugrue, M. , Talving, P. , Tan, B. K. , Tarasconi, A. , Tascini, C. , Tilsed, J. , Timsit, J. -.F. , Tumbarello, M. , Trung, N. T. , Ulrych, J. , Uranues, S. , Velmahos, G. , Vereczkei, A. G. , Viale, P. , Estape, J. V. , Viscoli, C. , Wagenlehner, F. , Wright, B. J. , Xiao, Y. , Yuan, K. -.C. , Zachariah, S. K. , Zahar, J. R. , Mergulhão, P. , Catena, Réanimation Médico-Chirurgicale, Groupe Hospitalier Paris Saint-Joseph, University Hospital Virgen Macarena, Internal Medicine Department, Universidad de Sevilla, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U912 INSERM - Aix Marseille Univ - IRD), Institut de Recherche pour le Développement (IRD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Service d'anesthésie - réanimation chirurgicale, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Klinik I für Innere Medizin und Zentrum für Klinische Studien (ZKS) 01KN0706, Universitätsklinikum Köln (Uniklinik Köln), AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), CHU Amiens-Picardie, Paracelsus Medizinische Privatuniversität = Paracelsus Medical University (PMU), Université Catholique de Louvain = Catholic University of Louvain (UCL), Center for Disease Dynamics, Economics & Policy (CDDEP), Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), Hartford Hospital, Department of Laboratory Medicine, Karolinska Institutet [Stockholm], Pathogénèse et contrôle des infections chroniques (PCCI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre Hospitalier Universitaire de Montpellier (CHU Montpellier ), Instituto Nacional de Matemática Pura e Aplicada (IMPA), Instituto Nacional de matematica pura e aplicada, 4th Department of Internal Medicine, ATTIKON University General Hospital, Department of Anesthesiology and Intensive Care, Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany], Critical Care Department, Joan XXIII University Hospital, Departmet of Infectious, Parasitic and Immune-Mediated Disease, Istituto Superiore di Sanita [Rome], Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Department of Internal Medicine, Geriatrics and Nephrologic Diseases, Section of Infectious Diseases, S.Orsola-Malpighi Hospital, Alma Mater Studiorum University of Bologna (UNIBO), Infectious Diseases, University of Genoa (UNIGE), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Groupe Hospitalier Paris Saint-Joseph (hpsj), Universidad de Sevilla / University of Sevilla, Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Nice Sophia Antipolis (1965 - 2019) (UNS), Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Istituto Superiore di Sanità (ISS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Università degli studi di Genova = University of Genoa (UniGe), Sartelli, Massimo, Kluger, Yoram, Ansaloni, Luca, Carlet, Jean, Dorj, Gereltuya, Catena, Fausto, [Sartelli, Massimo] Macerata Hosp, Dept Surg, Macerata, Italy, [Scibe, Rodolfo] Macerata Hosp, Dept Surg, Macerata, Italy, [Kluger, Yoram] Rambam Hlth Care Campus, Dept Gen Surg, Div Surg, Haifa, Israel, [Ben-Ishay, Ofir] Rambam Hlth Care Campus, Dept Gen Surg, Div Surg, Haifa, Israel, [Ansaloni, Luca] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Coccolini, Federico] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Ceresoli, Marco] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Montori, Giulia] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Carlet, Jean] World Alliance Antibiot Resistance, Paris, France, [Brink, Adrian] Milpark Hosp, Ampath Natl Lab Serv, Dept Clin Microbiol, Johannesburg, South Africa, [Brink, Adrian] Univ Cape Town, Dept Med, Div Infect Dis & HIV Med, Cape Town, South Africa, [Hardcastle, Timothy C.] Inkosi Albert Luthuli Cent Hosp, Trauma Serv, Durban, South Africa, [Hardcastle, Timothy C.] Nelson R Mandela Sch Clin Med, Dept Surg, Durban, South Africa, [Khanna, Ashish] Ctr Crit Care, Anaesthesiol Inst, Cleveland, OH USA, [Khanna, Ashish] Cleveland Clin, Dept Outcomes Res, Cleveland, OH 44106 USA, [Chicom-Mefire, Alain] Univ Buea, Dept Surg & Obstet Gynaecol, Buea, Cameroon, [Foianini, Esteban] Univ Buea, Dept Surg & Obstet Gynaecol, Buea, Cameroon, [Rodriguez-Bano, Jesus] Hosp Univ Virgen Macarena & Virge del Rocio IbiS, Unidad Clin Interctr Enfermedades Infecciosas Mic, Seville, Spain, [Rodriguez-Bano, Jesus] Univ Seville, Dept Med, Seville, Spain, [Nathwani, Dilip] Ninewells Hosp & Med Sch, Dundee, Scotland, [Mendelson, Marc] Univ Cape Town, Groote Schuur Hosp, Dept Med, Div Infect Dis & HIV Med, Cape Town, South Africa, [Watkins, Richard R.] Cleveland Clin Akron Gen, Div Infect Dis, Akron, OH USA, [Watkins, Richard R.] Northeast Ohio Med Univ, Rootstown, OH USA, [Pulcini, Celine] Lorraine Univ, EA APEMAC 4360, Nancy, France, [Pulcini, Celine] Nancy Univ Hosp, Infect Dis Dept, Nancy, France, [Beovic, Bojana] Univ Med Ctr Ljubljana, Ljubljana, Slovenia, [Beovic, Bojana] Univ Ljubljana, Fac Med, Ljubljana, Slovenia, [May, Addison K.] Vanderbilt Univ, Med Ctr, Div Trauma & Surg Crit Care, Nashville, TN USA, [Itani, Kamal M. F.] Boston Univ, Dept Surg, VA Boston Hlth Care Syst, Boston, MA 02215 USA, [Itani, Kamal M. F.] Harvard Med Sch, Boston, MA USA, [Mazuski, John E.] Washington Univ, Sch Med, Dept Surg, St Louis, MO 63110 USA, [Fry, Donald E.] Northwestern Univ, Feinberg Sch Med, Dept Surg, Chicago, IL 60611 USA, [Fry, Donald E.] Univ New Mexico, Sch Med, Albuquerque, NM 87131 USA, [Rasa, Kemal] Anadolu Med Ctr, Dept Surg, Kocaali, Turkey, [Montravers, Philippe] Bichat Claude Bernard Univ Hosp, Paris Diderot Sorbonne Cite Univ, Anesthesiol & Crit Care Med, HUPNSV, Paris, France, [Eckmann, Christian] Hannover Med Sch, Acad Hosp, Dept Gen Visceral & Thorac Surg, Peine, Germany, [Abbo, Lilian M.] Univ Miami, Miller Sch Med, Jackson Hlth Syst, Div Infect Dis, Miami, FL 33136 USA, [Abbo, Lilian M.] Bayero Univ, Dept Nursing Sci, Kano, Nigeria, [Abubakar, Salisu] UAE Univ, Coll Med & Hlth Sci, Dept Surg, Al Ain, U Arab Emirates, [Abu-Zidan, Fikri M.] Obafemi Awolowo Univ, Coll Hlth Sci, Dept Surg, Ife, Nigeria, [Al-Hasan, Majdi N.] Univ South Carolina, Sch Med, Dept Med, Div Infect Dis, Columbia, SC USA, [Althani, Asma A.] Qatar Univ, Biomed Res Ctr, Doha, Qatar, [Marei, Hany El-Sayed] Qatar Univ, Biomed Res Ctr, Doha, Qatar, [Ticas, Jorge Eduardo Alvarenga] Hosp Nacl Ros, Emergency Unit, San Salvador, El Salvador, [Ansari, Shamshul] Oita Univ, Dept Environm & Prevent Med, Fac Med, Oita, Japan, [Ansari, Shamshul] Chitwan Med Coll, Dept Microbiol, Bharatpur, Nepal, [Ansumana, Rashid] Univ Liverpool, Liverpool Sch Trop Med, Ctr Neglected Trop Dis, Bo, Sierra Leone, [Ansumana, Rashid] Njala Univ, Mercy Hosp, Res Lab, Bo, Sierra Leone, [Araujo da Silva, Andre Ricardo] Prontobaby Hosp Crianca, Infect Control Comm, Rio De Janeiro, Brazil, [Augustin, Goran] Univ Hosp Ctr, Dept Surg, Zagreb, Croatia, [Bala, Miklosh] Hadassah Hebrew Univ Med Ctr, Trauma & Acute Care Surg Unit, Jerusalem, Israel, [Balogh, Zsolt J.] John Hunter Hosp, Dept Traumatol, Newcastle, NSW, Australia, [Balogh, Zsolt J.] Univ Newcastle, Newcastle, NSW, Australia, [Baraket, Oussema] Bizerte Hosp, Dept Surg, Bizerte, Tunisia, [Bassett, Matteo] Santa Maria Misericordia Univ Hosp, Infect Dis Div, Udine, Italy, [Bellanova, Giovanni] SS Annunziata Hosp, Dept Surg, Taranto, Italy, [Beltran, Marcelo A.] Hosp San Juan Dios, Dept Gen Surg, La Serena, Chile, [Biffl, Walter L.] Queens Med Ctr, Acute Care Surg, Honolulu, HI USA, [Boermeester, Marja A.] Acad Med Ctr, Dept Surg, Amsterdam, Netherlands, [Brecher, Stephen M.] Boston Univ, Sch Med, VA Boston HealthCare Syst, Dept Pathol & Lab Med, Boston, MA 02118 USA, [Brecher, Stephen M.] Boston Univ, Sch Med, Dept Pathol & Lab Med, Boston, MA 02118 USA, [Bueno, Juan] Fdn Ctr Invest Bioprospecc & Biotecnol Biodivers, Barranquilla, Colombia, [Cainzos, Miguel A.] Hosp Clin Univ, Dept Surg, Santiago De Compostela, Spain, [Cairns, Kelly] Alfred Hlth, Pharm Dept, Melbourne, Vic, Australia, [Camacho-Ortiz, Adrian] Hosp Univ Dr Jose Eleuterio Gonzalez, Hosp Epidemiol & Infect Dis, Monterrey, Mexico, [Chandy, Sujith J.] Christian Med Coll & Hosp, Dept Pharmacol & Clin Pharmacol, Vellore, Tamil Nadu, India, [Cherry-Bukowiec, Jill R.] Univ Michigan, Dept Surg, Div Acute Care Surg, Ann Arbor, MI 48109 USA, [Cirocchi, Roberto] Univ Perugia, Dept Gen & Oncol Surg, Terni, Italy, [Colak, Elif] Hlth Sci Univ, Samsun Training & Res Hosp, Dept Gen Surg, Samsun, Turkey, [Corcione, Antonio] AORN Colli Vincenzo Monaldi Hosp, Anesthesia & Intens Care Unit, Naples, Italy, [Cornely, Oliver A.] Univ Cologne, German Ctr Infect Res DZIF, Dept Internal Med 1, Cologne Excellence Cluster Cellular Stress Respon, Cologne, Germany, [Cortese, Francesco] San Filippo Neris Hosp, Emergency Surg Unit, Rome, Italy, [Cui, Yunfeng] Tianjin Med Univ, Tianjin Nankai Hosp, Dept Surg, Nankai Clin Sch Med, Tianjin, Peoples R China, [Curcio, Daniel] Buenos Aires Univ, Infectol Inst SRL, Buenos Aires, DF, Argentina, [Damaskos, Dimitris] Royal Infirm Edinburgh NHS Trust, Dept Surg, Edinburgh, Midlothian, Scotland, [Das, Koray] Ankara Numune Training & Res Hosp, Dept Surg, Adana, Turkey, [Delibegovic, Samir] Univ Clin Ctr Tuzla, Dept Surg, Tuzla, Bosnia & Herceg, [Deme-Trashvili, Zaza] Kipshidze Cent Univ Hosp, Dept Gen Surg, Tbilisi, Georgia, [De Simone, Belinda] Cannes Hosp, Dept Digest Surg, Cannes, France, [de Souza, Hamilton Petry] Pontificia Univ Catolica Rio Grande do Sul PUCRS, Sch Med, Dept Surg, Porto Alegre, RS, Brazil, [De Waele, Jan] Ghent Univ Hosp, Dept Crit Care Med, Ghent, Belgium, [Dhingra, Sameer] Univ West Indies, Eric Williams Med Sci Complex, Sch Pharm, Fac Med Sci, Uriah Butler Highway, Champ Fleurs, Trinidad Tobago, [Diaz, Jose J.] Univ Maryland, R Adams Cowley Shock Trauma Ctr, Div Acute Care Surg, Program Trauma, Baltimore, MD 21201 USA, [Di Carlo, Isidoro] Univ Catania, Cannizzaro Hosp, Dept Surg Sci, Catania, Italy, [Di Marzo, Francesco] Versilia Hosp, Gen Surg, Usl Nordovest, Tuscany, Italy, [Di Saverio, Salomone] Maggiore Hosp, Dept Surg, Bologna, Italy, [Dogjani, Agron] Univ Hosp Trauma, Dept Surg, Tirana, Albania, [Dorj, Gereltuya] Mongolian Natl Univ Med Sci, Sch Pharm, Ulaanbaatar, Mongolia, [Dortet, Laurent] Paris Sud Univ, Bicetre Hosp, Dept Microbiol, La Kremlin Bicetre, France, [Duane, Therese M.] John Peter Smith Hlth Network, Dept Surg, Ft Worth, TX USA, [Dupont, Herve] Univ Picardie Jules Verne, CHU Amiens Picardie, Dept Anesthesie Reanimat, Amiens, France, [Dupont, Herve] Univ Picardie Jules Verne, INSERM, U1088, Amiens, France, [Egiev, Valery N.] Pirogov Russian Natl Res Med Univ, Dept Surg, Moscow, Russia, [Eid, Hani O.] Al Ain Hosp, Mediclin Middle East, Dept Emergency Med, Al Ain, U Arab Emirates, [Elmangory, Mutasim] Fed Minist Hlth, Sudan Natl Publ Hlth Lab, Khartoum, Sudan, [Enani, Mushira Abdulaziz] King Fahad Med City, Div Infect Dis, Dept Med, Riyadh, Saudi Arabia, [Escandon-Vargas, Kevin] Univ Valle, Escuela Med, Fac Salud, Cali, Colombia, [Faro Junior, Mario P.] ABC Med Sch, Dept Gen Surg Trauma, Santo Andre, SP, Brazil, [Faro Junior, Mario P.] ABC Med Sch, Emergency Surg Div, Santo Andre, SP, Brazil, [Ferrada, Paula] Virginia Commonwealth Univ, Dept Surg, Richmond, VA USA, [Foghetti, Domitilla] Pesaro Hosp, Dept Surg, Pesaro, Italy, Clin Foianini, Dept Surg, Santa Cruz, Bolivia, [Fraga, Gustavo P.] Univ Campinas Unicamp, Sch Med Sci, Dept Surg, Div Trauma Surg, Campinas, SP, Brazil, [Frattima, Sabrina] Ist Clin San Rocco Franciacorta, Brescia, Italy, [Gandhi, Chinmay] Bharati Vidyapeeth Deemed Univ Med Coll & Hosp, Dept Surg, Sangli, Maharashtra, India, [Gattuso, Gianni] C Poma Hosp, Infect Dis Dept, Mantua, Italy, [Giamarellou, Eleni] Hygeia Gen Hosp, Dept Internal Med 6, Athens, Greece, [Ghnnam, Wagih] Mansoura Univ, Mansoura Fac Med, Dept Gen Surg, Mansoura, Egypt, [Gkiokas, George] Natl & Kapodistrian Univ Athens, Aretaieion Univ Hosp, Dept Surg 2, Athens, Greece, [Girardis, Massimo] Modena Univ Hosp, Intens Care Unit, Modena, Italy, [Goff, Debbie A.] Ohio State Univ, Wexner Med Ctr, Columbus, OH 43210 USA, [Gomes, Carlos Augusto] Hosp Univ Terezinha Jesus, Dept Surg, Fac Ciencias Med & Saude Juiz de Fora, Juiz De Fora, Brazil, [Gomi, Harumi] Univ Tsukuba, Mito Kyodo Gen Hosp, Ctr Global Hlth, Mito, Ibaraki, Japan, [Guerra Gronerth, Rosio Isabel] Peruvian Navy Med Ctr, Lima, Peru, [Guirao, Xavier] Parc Tauli Univ Hosp, Dept Gen Surg, Unit Endocrine Head & Neck Surg, Sabadell, Spain, [Guirao, Xavier] Parc Tauli Univ Hosp, Dept Gen Surg, Unit Surg Infect Support, Sabadell, Spain, [Guzman-Blanco, Manuel] Hosp Privado Ctr Med Caracas, Caracas, Venezuela, [Guzman-Blanco, Manuel] Hosp Vargas Caracas, Caracas, Venezuela, [Haque, Mainul] Univ Pertahanan Nasional Malaysia, Natl Def Univ Malaysia, Unit Pharmacol, Fac Med & Def Hlth, Kuala Lumpur, Malaysia, [Reichert, Martin] Univ Pertahanan Nasional Malaysia, Natl Def Univ Malaysia, Unit Pharmacol, Fac Med & Def Hlth, Kuala Lumpur, Malaysia, [Hecker, Andreas] Univ Hosp Giessen, Dept Gen & Thorac Surg, Giessen, Germany, [Hell, Markus] Paracelsus Med Univ, Acad Teaching Lab, Clin Microbiol & Infect Control, MEDILAB Dr Mustafa Dr Richter OG, Salzburg, Austria, [Herzog, Torsten] Ruhr Univ Bochum, St Josef Hosp, Dept Surg, Bochum, Germany, [Hicks, Lauri] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA USA, [Kafka-Ritsch, Reinhold] Innsbruck Med Univ, Dept Visceral Transplant & Thorac Surg, Innsbruck, Austria, [Kao, Lillian S.] Univ Texas Hlth Sci Ctr Houston, Dept Surg, Houston, TX 77030 USA, [Kanj, Souha S.] Amer Univ Beirut, Dept Internal Med, Div Infect Dis, Beirut, Lebanon, [Kaplan, Lewis J.] Univ Penn, Perelman Sch Med, Philadelphia VA Med Ctr, Dept Surg, Philadelphia, PA 19104 USA, [Kapoor, Garima] Gandhi Med Coll, Dept Microbiol, Bhopal, India, [Karamarkovic, Aleksandar] Univ Belgrade, Clin Emergency Surg, Med Fac, Belgrade, Serbia, [Kashuk, Jeffry] Tel Aviv Univ, Dept Surg, Assia Med Grp, Sackler Sch Med, Tel Aviv, Israel, [Kenig, Jakub] Jagiellonian Univ, Med Coll, Dept Gen Surg 3, Krakow, Poland, [Khamis, Faryal] Royal Hosp, Dept Internal Med, Muscat, Oman, [Khokha, Vladimir] City Hosp, Dept Emergency Surg, Mozyr, BELARUS, [Kiguba, Ronald] Makerere Univ, Dept Pharmacol & Therapeut, Coll Hlth Sci, Kampala, Uganda, [Kirkpatrick, Andrew W.] Foothills Med Ctr, Gen Acute Care Abdominal Wall Reconstruct & Traum, Calgary, AB, Canada, [Korner, Hartwig] Stavanger Univ Hosp, Dept Gastrointestinal Surg, Stavanger, Norway, [Koike, Kaoru] Kyoto Univ, Grad Sch Med, Dept Primary Care & Emergency Med, Kyoto, Japan, [Kok, Kenneth Y. Y.] Brunei Canc Ctr, Dept Surg, Jerudong Pk, Jerudong, Brunei, [Kon, Kateryna] Kharkiv Natl Med Univ, Dept Microbiol Virol & Immunol, Kharkov, Ukraine, [Kong, Victor] Edendale Hosp, Dept Surg, Pietermaritzburg, South Africa, [Inaba, Kenji] Univ Southern Calif, Los Angeles Cty & Univ So Cali fornia Med Ctr, Div Acute Care Surg & Surg Crit Care, Dept Surg, Los Angeles, CA USA, [Ioannidis, Orestis] Aristotle Univ Thessaloniki, Gen Hosp G Papanikolaou, Surg Dept 4, Med Sch, Thessaloniki, Greece, [Isik, Arda] Erzincan Univ, Dept Gen Surg, Fac Med, Erzincan, Turkey, [Iskandar, Katia] Lebanese Int Univ, Dept Pharm, Beirut, Lebanon, [Labbate, Maurizio] Univ Technol Sydney, Sch Life Sci, Sydney, NSW, Australia, [Labbate, Maurizio] Univ Technol Sydney, Inst I3, Sydney, NSW, Australia, [Labricciosa, Francesco M.] UNIVPM, Dept Biomed Sci & Publ Hlth, Unit Hyg Prevent Med & Publ Hlth, Ancona, Italy, [Lagrou, Katrien] Univ Hosp Leuven, Clin Dept Lab Med, Leuven, Belgium, [Lagrou, Katrien] Katholieke Univ Leuven, Dept Microbiol & Immunol, Leuven, Belgium, [Lagunes, Leonel] Hosp Cent Dr Ignacio Morones Prieto, San Luis Potosi, Mexico, [Latifi, Rifat] Univ Arizona, Dept Surg, Div Trauma, Tucson, AZ USA, [Lasithiotakis, Kostas] York Teaching Hosp NHS Fdn Trust, Dept Surg, York, N Yorkshire, England, [Laxminarayan, Ramanan] Ctr Dis Dynam Econ & Policy, Washington, DC USA, [Lee, Jae Gil] Yonsei Univ, Coll Med, Dept Surg, Seoul, South Korea, [Leone, Marc] Aix Marseille Univ, Hop Nord, AP HM, Dept Anaesthesiol & Crit Care, Marseille, France, [Leppaniemi, Ari] Univ Hosp Meilahti, Abdominal Ctr, Helsinki, Finland, [Li, Yousheng] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 9, Dept Surg, Shanghai, Peoples R China, [Liang, Stephen Y.] Washington Univ, Sch Med, Div Infect Dis, Div Emergency Med, St Louis, MO USA, [Liau, Kui-Hin] Natl Univ Singapore, Mt Elizabeth Novena Hosp, Singapore & Yong Loo Lin Sch Med, Dept Surg,Liau KH Consulting, Singapore, Singapore, [Litvin, Andrey] Immanuel Kant Balt Fed Univ, Surg Disciplines, Reg Clin Hosp, Kaliningrad, Russia, [Loho, Tonny] Univ Indonesia, Cipto Mangunkusumo Gen Hosp, Dept Clin Pathol, Div Infect Dis,Fac Med, Jakarta, Indonesia, [Lowman, Warren] Univ Witwatersrand, Sch Pathol, Vermaak Partners Pathcare Pathologists, Clin Microbiol & Infect Dis,Fac Hlth Sci, Johannesburg, South Africa, [Lowman, Warren] Wits Donald Gordon Med Ctr, Johannesburg, South Africa, [Machain, Gustavo M.] Univ Nacl Asuncion, Dept Surg, Asuncion, Paraguay, [Segovia Lohse, Helmut] Univ Nacl Asuncion, Dept Surg, Asuncion, Paraguay, [Maier, Ronald V.] Univ Washington, Dept Surg, Seattle, WA 98195 USA, [Manzano-Nunez, Ramiro] Fdn Valle Lili, Clin Res Ctr, Cali, Colombia, [Marinis, Athanasios] Tzane Gen Hosp, Dept Surg 1, Piraeus, Greece, [Marmorale, Cristina] Univ Politecn Marche, Dept Surg, Ancona, Italy, [Martin-Loeches, Ignacio] St James Univ Hosp, Trin Ctr Hlth Sci, Dept Clin Med, Wellcome Trust HRB Clin Res,MICRO, Dublin, Ireland, [Marwah, Sanjay] Postgrad Inst Med Sci, Dept Surg, Rohtak, Haryana, India, [Maseda, Emilio] Hosp Univ La Paz Madrid, Serv Anestesia & Reanimac, Madrid, Spain, [McFarlane, Michael] Univ Hosp West Indies, Dept Surg Radiol, Kingston, Jamaica, [de Melo, Renato Bessa] Ctr Hosp Sao Joao, Gen Surg Dept, Porto, Portugal, [Melotti, Maria Rita] Alma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Anesthesiol & Intens Care, Bologna, Italy, [Memish, Ziad] Minist Hlth, Prince Mohamed Bin Abdulaziz Hosp, Dept Med, Infect Dis Div, Riyadh, Saudi Arabia, [Mertz, Dominik] McMaster Univ, Dept Med, Hamilton, ON, Canada, [Mertz, Dominik] McMaster Univ, Dept Clin Epidemiol & Biostat, Dept Pathol & Mol Med, Hamilton, ON, Canada, [Mesina, Cristian] Emergency Hosp Craiova, Surg Clin 2, Craiova, Romania, [Menichetti, Francesco] Univ Hosp Pisa, Infect Dis Unit, Pisa, Italy, [Mishra, Shyam Kumar] Tribhuvan Univ, Teaching Hosp, Inst Med, Dept Microbiol, Kathmandu, Nepal, [Moore, Ernest E.] Univ Colorado, Denver 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Tadeja] UMC Ljubljana, Dept Surg, Ljubljana, Slovenia, [Ponce-de-Leon, Alfredo] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Infect Dis, Lab Clin Microbiol, Mexico City, DF, Mexico, [Popovski, Zagorka] Hamilton Hlth Sci, Hamilton, ON, Canada, [Popovski, Zagorka] London Hlth Sci, London, ON, Canada, [Poulakou, Garyphallia] Attikon Univ Gen Hosp, Med Sch, Natl & Kapodistrian Univ Athens, Dept Internal Med 4, Athens, Greece, [Poulakou, Garyphallia] Attikon Univ Gen Hosp, Med Sch, Natl & Kapodistrian Univ Athens, Infect Dis Unit, Athens, Greece, [Preller, Jacobus] Univ Hosp NHS Fdn Trust, John Farman Intens Care Unit, Cambridge, England, [Guerrero, Adrian Puello] Univ Autonoma Santo Domingo, Inst Nacl Canc Rosa Tavares INCART, Santo Domingo, Dominican Rep, [Pupelis, Guntars] Riga East Univ Hosp Gailezers, Dept Gen & Emergency Surg, Riga, Latvia, [Quiodettis, Martha] Hosp Santo Tomas, Dept Trauma, Panama City, Panama, [Rawson, Timothy M.] Natl Inst Hlth Res, Imperial Coll London, Hlth Protect Res Unit Healthcare Associated Infec, Hammersmith Campus, London, England, [Reinhart, Konrad] Jena Univ Hosp, Dept Anesthesiol & Intens Care Med, Jena, Thuringen, Germany, [Rems, Miran] Jesenice Gen Hosp, Dept Gen Surg, Jesenice, Slovenia, [Rello, Jordi] VHIR, Dept Clin Res & Innovat Pneumonia & Sepsis, Barcelona, Spain, [Rizoli, Sandro] Univ Toronto, St Michaels Hosp, Trauma & Acute Care Serv, Toronto, ON, Canada, [Roberts, Jason] Univ Queensland, Fac Med, Brisbane, Qld, Australia, [Rubio-Perez, Ines] La Paz Univ Hosp, Gen Surg Dept, Colorectal Surg Unit, Madrid, Spain, [Ruppc, Etienne] Bichat Claude Bernard Univ Hosp, Paris Diderot Sorbonne Univ, Serv Bacteriol, HUPNSV, Paris, France, [Sakakushev, Boris] Univ Hosp St George, Med Univ, Gen Surg Dept, Plovdiv, Bulgaria, [Sall, Ibrahima] Mil Teaching Hosp, Gen Surg Dept, Dakar, Senegal, [Kafil, Hossein Samadi] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran, [Sanders, James] JPS Hlth Network, Ft Worth, TX USA, [Sato, Norio] Ehime Univ, Grad Sch Med, Dept Aeromed Serv Emergency & Trauma Care, Matsuyama, Ehime, Japan, [Sawyer, Robert G.] Western Michigan Univ, Sch Med, Dept Surg, Kalamazoo, MI 49008 USA, [Scalea, Thomas] Univ Maryland, Sch Med, Dept Trauma Surg, Baltimore, MD 21201 USA, [Scudeller, Luigia] IRCCS Policlin San Matteo Fdn, Clin Epidemiol Unit, Pavia, Italy, [Sganga, Gabriele] Univ Cattolica Sacro Cuore, Policlin A Gemelli, Dept Surg, Rome, Italy, [Shafiq, Nusrat] Postgrad Inst Med Educ & Res, Dept Pharmacol, Chandigarh, India, [Shah, Jay N.] Patan Acad Hlth Sci, Dept Surg Patan Hosp, Kathmandu, Nepal, [Spigaglia, Patrizia] Ist Super Sanita, Dept Infect Dis, Rome, Italy, [Suroowan, Shanoo] Univ Mauritius, Dept Hlth Sci, Fac Sci, Reduit, Mauritius, [Tsioutis, Constantinos] European Univ Cyprus, Sch Med, Nicosia, Cyprus, [Sifri, Costi D.] Univ Virginia Hlth Syst, Off Hosp Epidemiol Infect Prevent & Control, Charlottesville, VA USA, [Siribumrungwong, Boonying] Thammasat Univ Hosp, Thammasat Univ, Dept Surg, Fac Med, Pathum Thani, Thailand, [Sugrue, Michael] Letterkenny Hosp, Gen Surg Dept, Letterkenny, Ireland, [Talving, Peep] North Estonia Med Ctr, Dept Surg, Tallinn, Estonia, [Tan, Boun Kim] Ctr Hosp St Joseph St Luc, Intens Care Unit, Lyon, France, [Tarasconi, Antonio] Parma Maggiore Hosp, Dept Emergency Surg, Parma, Italy, [Catena, Fausto] Parma Maggiore Hosp, Dept Emergency Surg, Parma, Italy, [Tascini, Carlo] Cotugno Hosp, Azienda Osped Colli, Div Infect Dis 1, Naples, Italy, [Tilsed, Jonathan] Hull & East Yorkshire Hosp NHS Trust, Surg Hlth Care Grp, Kingston Upon Hull, N Humberside, England, [Timsit, Jean-Francois] Hop Xavier Bichat, PHP Med & Infect Dis ICU, Paris, France, [Tumbarello, Mario] Catholic Univ, Inst Infect Dis, Rome, Italy, [Ngo Tat Trung] Tran Hung Dao Hosp, Dept Mol Biol, Hanoi, Vietnam, [Ulrych, Jan] Charles Univ Prague, Fac Med 1, Dept Surg 1, Prague, Czech Republic, [Ulrych, Jan] Gen Univ Hosp Prague, Prague, Czech Republic, [Uranues, Selman] Med Univ Graz, Dept Surg, Graz, Austria, [Velmahos, George] Massachusetts Gen Hosp, Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USA, [Vereczkei, Andras G.] Med Sch Univ Pecs, Dept Surg, Pecs, Hungary, [Viale, Pierluigi] Alma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy, [Vila Estape, Jordi] Univ Barcelona, ISGlobal Hosp Clin, Inst Salud Global, Barcelona, Spain, [Viscoli, Claudio] Univ Genoa DISSAL, Osped Policlin San Martino IRCCS Oncol, Infect Dis Unit, Genoa, Italy, [Wagenlehner, Florian] Univ Giessen, Dept Urol Pediat Urol & Androl, Med Fac Justus Liebig, Giessen, Germany, [Wright, Brian J.] SUNY Stony Brook, Sch Med, Dept Emergency Med & Neurosurg, Stony Brook, NY 11794 USA, [Xiao, Yonghong] Zhejiang Univ, Affilliated Hosp 1, State Key Lab Diag & Treatment Infect Dis, Hangzhou, Zhejiang, Peoples R China, [Yuan, Kuo-Ching] Chang Gung Mem Hosp, Trauma & Emergency Surg Dept, Taoyuan, Taiwan, [Zachariah, Sanoop K.] MOSC Med Coll Kolenchery, Dept Surg, Cochin, Kerala, India, [Zahar, Jean Ralph] Angers Univ, CHU Angers, Infect Control Unit, Angers, France, COMBE, Isabelle, Sartelli, M, Kluger, Y, Ansaloni, L, Carlet, J, Brink, A, Hardcastle, T, Khanna, A, Chicom-Mefire, A, Rodriguez-Bano, J, Nathwani, D, Mendelson, M, Watkins, R, Pulcini, C, Beovic, B, May, A, Itani, K, Mazuski, J, Fry, D, Coccolini, F, Rasxa, K, Montravers, P, Eckmann, C, Abbo, L, Abubakar, S, Abu-Zidan, F, Adesunkanmi, A, Al-Hasan, M, Althani, A, Ticas, J, Ansari, S, Ansumana, R, Da Silva, A, Augustin, G, Bala, M, Balogh, Z, Baraket, O, Bassetti, M, Bellanova, G, Beltran, M, Ben-Ishay, O, Biffl, W, Boermeester, M, Brecher, S, Bueno, J, Cainzos, M, Cairns, K, Camacho-Ortiz, A, Ceresoli, M, Chandy, S, Cherry-Bukowiec, J, Cirocchi, R, Colak, E, Corcione, A, Cornely, O, Cortese, F, Cui, Y, Curcio, D, Damaskos, D, Dasx, K, Delibegovic, S, Demetrashvili, Z, De Simone, B, De Souza, H, De Waele, J, Dhingra, S, Diaz, J, Di Carlo, I, Di Marzo, F, Di Saverio, S, Dogjani, A, Dorj, G, Dortet, L, Duane, T, Dupont, H, Egiev, V, Eid, H, Elmangory, M, El-Sayed Marei, H, Enani, M, Escandon-Vargas, K, Faro, M, Ferrada, P, Foghetti, D, Foianini, E, Fraga, G, Frattima, S, Gandhi, C, Gattuso, G, Giamarellou, E, Ghnnam, W, Gkiokas, G, Girardis, M, Goff, D, Gomes, C, Gomi, H, Gronerth, R, Guirao, X, Guzman-Blanco, M, Haque, M, Hecker, A, Hell, M, Herzog, T, Hicks, L, Kafka-Ritsch, R, Kao, L, Kanj, S, Kaplan, L, Kapoor, G, Karamarkovic, A, Kashuk, J, Kenig, J, Khamis, F, Khokha, V, Kiguba, R, Kirkpatrick, A, Korner, H, Koike, K, Kok, K, Kon, K, Kong, V, Inaba, K, Ioannidis, O, Isik, A, Iskandar, K, Labbate, M, Labricciosa, F, Lagrou, K, Lagunes, L, Latifi, R, Lasithiotakis, K, Laxminarayan, R, Lee, J, Leone, M, Leppaniemi, A, Li, Y, Liang, S, Liau, K, Litvin, A, Loho, T, Lowman, W, Machain, G, Maier, R, Manzano-Nunez, R, Marinis, A, Marmorale, C, Martin-Loeches, I, Marwah, S, Maseda, E, Mcfarlane, M, De Melo, R, Melotti, M, Memish, Z, Mertz, D, Mesina, C, Menichetti, F, Mishra, S, Montori, G, Moore, E, Moore, F, Naidoo, N, Napolitano, L, Negoi, I, Nicolau, D, Nikolopoulos, I, Nord, C, Ofori-Asenso, R, Olaoye, I, Omari, A, Ordonez, C, Ouadii, M, Ouedraogo, A, Pagani, L, Paiva, J, Parreira, J, Pata, F, Pereira, J, Pereira, N, Petrosillo, N, Picetti, E, Pintar, T, Ponce-De-Leon, A, Popovski, Z, Poulakou, G, Preller, J, Guerrero, A, Pupelis, G, Quiodettis, M, Rawson, T, Reichert, M, Reinhart, K, Rems, M, Rello, J, Rizoli, S, Roberts, J, Rubio-Perez, I, Ruppe, E, Sakakushev, B, Sall, I, Kafil, H, Sanders, J, Sato, N, Sawyer, R, Scalea, T, Scibe, R, Scudeller, L, Lohse, H, Sganga, G, Shafiq, N, Shah, J, Spigaglia, P, Suroowan, S, Tsioutis, C, Sifri, C, Siribumrungwong, B, Sugrue, M, Talving, P, Tan, B, Tarasconi, A, Tascini, C, Tilsed, J, Timsit, J, Tumbarello, M, Trung, N, Ulrych, J, Uranues, S, Velmahos, G, Vereczkei, A, Viale, P, Estape, J, Viscoli, C, Wagenlehner, F, Wright, B, Xiao, Y, Yuan, K, Zachariah, S, Zahar, J, 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Subjects
0301 basic medicine, antibiotic agent, antifungal agent antiinfective agent, Antifungal Agents, Drug Resistance, Declaration, Inappropriate Prescribing, 030230 surgery, Global Health, Antimicrobial Stewardship, Microbial, 0302 clinical medicine, Anti-Infective Agents, Health care, Global health, Antimicrobial stewardship, Antibiotic prophylaxis, Antibiotic stewardship, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Drug Resistance, Microbial, Public relations, Antimicrobial, Operative, Anti-Bacterial Agents, Antibiotic Prophylaxis, Humans, Surgical Procedures, Operative, Surgical Wound Infection, Surgery, Microbiology (medical), Infectious Diseases, 3. Good health, surgical infections, medicine.medical_specialty, 030106 microbiology, Guidelines, 03 medical and health sciences, Antibiotic resistance, medicine, Ventilator-associated pneumonia, Adults, Surgical Procedures, business.industry, Carbapenems, Therapy, business, hospitals, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

International audience; This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections. As such, it is our intent to raise awareness among healthcare workers and improve antimicrobial prescribing. To facilitate its dissemination, the declaration was translated in different languages.

Published
2017
Full Text
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3. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

Author

Sartelli, M, Kluger, Y, Ansaloni, L, Carlet, J, Brink, A, Hardcastle, T, Khanna, A, Chicom-Mefire, A, Rodriguez-Bano, J, Nathwani, D, Mendelson, M, Watkins, R, Pulcini, C, Beovic, B, May, A, Itani, K, Mazuski, J, Fry, D, Coccolini, F, Rasxa, K, Montravers, P, Eckmann, C, Abbo, L, Abubakar, S, Abu-Zidan, F, Adesunkanmi, A, Al-Hasan, M, Althani, A, Ticas, J, Ansari, S, Ansumana, R, Da Silva, A, Augustin, G, Bala, M, Balogh, Z, Baraket, O, Bassetti, M, Bellanova, G, Beltran, M, Ben-Ishay, O, Biffl, W, Boermeester, M, Brecher, S, Bueno, J, Cainzos, M, Cairns, K, Camacho-Ortiz, A, Ceresoli, M, Chandy, S, Cherry-Bukowiec, J, Cirocchi, R, Colak, E, Corcione, A, Cornely, O, Cortese, F, Cui, Y, Curcio, D, Damaskos, D, Dasx, K, Delibegovic, S, Demetrashvili, Z, De Simone, B, De Souza, H, De Waele, J, Dhingra, S, Diaz, J, Di Carlo, I, Di Marzo, F, Di Saverio, S, Dogjani, A, Dorj, G, Dortet, L, Duane, T, Dupont, H, Egiev, V, Eid, H, Elmangory, M, El-Sayed Marei, H, Enani, M, Escandon-Vargas, K, Faro, M, Ferrada, P, Foghetti, D, Foianini, E, Fraga, G, Frattima, S, Gandhi, C, Gattuso, G, Giamarellou, E, Ghnnam, W, Gkiokas, G, Girardis, M, Goff, D, Gomes, C, Gomi, H, Gronerth, R, Guirao, X, Guzman-Blanco, M, Haque, M, Hecker, A, Hell, M, Herzog, T, Hicks, L, Kafka-Ritsch, R, Kao, L, Kanj, S, Kaplan, L, Kapoor, G, Karamarkovic, A, Kashuk, J, Kenig, J, Khamis, F, Khokha, V, Kiguba, R, Kirkpatrick, A, Korner, H, Koike, K, Kok, K, Kon, K, Kong, V, Inaba, K, Ioannidis, O, Isik, A, Iskandar, K, Labbate, M, Labricciosa, F, Lagrou, K, Lagunes, L, Latifi, R, Lasithiotakis, K, Laxminarayan, R, Lee, J, Leone, M, Leppaniemi, A, Li, Y, Liang, S, Liau, K, Litvin, A, Loho, T, Lowman, W, Machain, G, Maier, R, Manzano-Nunez, R, Marinis, A, Marmorale, C, Martin-Loeches, I, Marwah, S, Maseda, E, Mcfarlane, M, De Melo, R, Melotti, M, Memish, Z, Mertz, D, Mesina, C, Menichetti, F, Mishra, S, Montori, G, Moore, E, Moore, F, Naidoo, N, Napolitano, L, Negoi, I, Nicolau, D, Nikolopoulos, I, Nord, C, Ofori-Asenso, R, Olaoye, I, Omari, A, Ordonez, C, Ouadii, M, Ouedraogo, A, Pagani, L, Paiva, J, Parreira, J, Pata, F, Pereira, J, Pereira, N, Petrosillo, N, Picetti, E, Pintar, T, Ponce-De-Leon, A, Popovski, Z, Poulakou, G, Preller, J, Guerrero, A, Pupelis, G, Quiodettis, M, Rawson, T, Reichert, M, Reinhart, K, Rems, M, Rello, J, Rizoli, S, Roberts, J, Rubio-Perez, I, Ruppe, E, Sakakushev, B, Sall, I, Kafil, H, Sanders, J, Sato, N, Sawyer, R, Scalea, T, Scibe, R, Scudeller, L, Lohse, H, Sganga, G, Shafiq, N, Shah, J, Spigaglia, P, Suroowan, S, Tsioutis, C, Sifri, C, Siribumrungwong, B, Sugrue, M, Talving, P, Tan, B, Tarasconi, A, Tascini, C, Tilsed, J, Timsit, J, Tumbarello, M, Trung, N, Ulrych, J, Uranues, S, Velmahos, G, Vereczkei, A, Viale, P, Estape, J, Viscoli, C, Wagenlehner, F, Wright, B, Xiao, Y, Yuan, K, Zachariah, S, Zahar, J, Mergulhao, P, Catena, F, Sartelli M., Kluger Y., Ansaloni L., Carlet J., Brink A., Hardcastle T. C., Khanna A., Chicom-Mefire A., Rodriguez-Bano J., Nathwani D., Mendelson M., Watkins R. R., Pulcini C., Beovic B., May A. K., Itani K. M. F., Mazuski J. E., Fry D. E., Coccolini F., Rasxa K., Montravers P., Eckmann C., Abbo L. M., Abubakar S., Abu-Zidan F. M., Adesunkanmi A. K., Al-Hasan M. N., Althani A. A., Ticas J. E. A., Ansari S., Ansumana R., Da Silva A. R. A., Augustin G., Bala M., Balogh Z. J., Baraket O., Bassetti M., Bellanova G., Beltran M. A., Ben-Ishay O., Biffl W. L., Boermeester M. A., Brecher S. M., Bueno J., Cainzos M. A., Cairns K., Camacho-Ortiz A., Ceresoli M., Chandy S. J., Cherry-Bukowiec J. R., Cirocchi R., Colak E., Corcione A., Cornely O. A., Cortese F., Cui Y., Curcio D., Damaskos D., Dasx K., Delibegovic S., Demetrashvili Z., De Simone B., De Souza H. P., De Waele J., Dhingra S., Diaz J. J., Di Carlo I., Di Marzo F., Di Saverio S., Dogjani A., Dorj G., Dortet L., Duane T. M., Dupont H., Egiev V. N., Eid H. O., Elmangory M., El-Sayed Marei H., Enani M. A., Escandon-Vargas K., Faro M. P., Ferrada P., Foghetti D., Foianini E., Fraga G. P., Frattima S., Gandhi C., Gattuso G., Giamarellou E., Ghnnam W., Gkiokas G., Girardis M., Goff D. A., Gomes C. A., Gomi H., Gronerth R. I. G., Guirao X., Guzman-Blanco M., Haque M., Hecker A., Hell M., Herzog T., Hicks L., Kafka-Ritsch R., Kao L. S., Kanj S. S., Kaplan L. J., Kapoor G., Karamarkovic A., Kashuk J., Kenig J., Khamis F., Khokha V., Kiguba R., Kirkpatrick A. W., Korner H., Koike K., Kok K. Y. Y., Kon K., Kong V., Inaba K., Ioannidis O., Isik A., Iskandar K., Labbate M., Labricciosa F. M., Lagrou K., Lagunes L., Latifi R., Lasithiotakis K., Laxminarayan R., Lee J. G., Leone M., Leppaniemi A., Li Y., Liang S. Y., Liau K. -H., Litvin A., Loho T., Lowman W., Machain G. M., Maier R. V., Manzano-Nunez R., Marinis A., Marmorale C., Martin-Loeches I., Marwah S., Maseda E., McFarlane M., De Melo R. B., Melotti M. R., Memish Z., Mertz D., Mesina C., Menichetti F., Mishra S. K., Montori G., Moore E. E., Moore F. A., Naidoo N., Napolitano L., Negoi I., Nicolau D. P., Nikolopoulos I., Nord C. E., Ofori-Asenso R., Olaoye I., Omari A. H., Ordonez C. A., Ouadii M., Ouedraogo A. -S., Pagani L., Paiva J. A., Parreira J. G., Pata F., Pereira J., Pereira N. R., Petrosillo N., Picetti E., Pintar T., Ponce-De-Leon A., Popovski Z., Poulakou G., Preller J., Guerrero A. P., Pupelis G., Quiodettis M., Rawson T. M., Reichert M., Reinhart K., Rems M., Rello J., Rizoli S., Roberts J., Rubio-Perez I., Ruppe E., Sakakushev B., Sall I., Kafil H. S., Sanders J., Sato N., Sawyer R. G., Scalea T., Scibe R., Scudeller L., Lohse H. S., Sganga G., Shafiq N., Shah J. N., Spigaglia P., Suroowan S., Tsioutis C., Sifri C. D., Siribumrungwong B., Sugrue M., Talving P., Tan B. K., Tarasconi A., Tascini C., Tilsed J., Timsit J. -F., Tumbarello M., Trung N. T., Ulrych J., Uranues S., Velmahos G., Vereczkei A. G., Viale P., Estape J. V., Viscoli C., Wagenlehner F., Wright B. J., Xiao Y., Yuan K. -C., Zachariah S. K., Zahar J. R., Mergulhao P., Catena F., Sartelli, M, Kluger, Y, Ansaloni, L, Carlet, J, Brink, A, Hardcastle, T, Khanna, A, Chicom-Mefire, A, Rodriguez-Bano, J, Nathwani, D, Mendelson, M, Watkins, R, Pulcini, C, Beovic, B, May, A, Itani, K, Mazuski, J, Fry, D, Coccolini, F, Rasxa, K, Montravers, P, Eckmann, C, Abbo, L, Abubakar, S, Abu-Zidan, F, Adesunkanmi, A, Al-Hasan, M, Althani, A, Ticas, J, Ansari, S, Ansumana, R, Da Silva, A, Augustin, G, Bala, M, Balogh, Z, Baraket, O, Bassetti, M, Bellanova, G, Beltran, M, Ben-Ishay, O, Biffl, W, Boermeester, M, Brecher, S, Bueno, J, Cainzos, M, Cairns, K, Camacho-Ortiz, A, Ceresoli, M, Chandy, S, Cherry-Bukowiec, J, Cirocchi, R, Colak, E, Corcione, A, Cornely, O, Cortese, F, Cui, Y, Curcio, D, Damaskos, D, Dasx, K, Delibegovic, S, Demetrashvili, Z, De Simone, B, De Souza, H, De Waele, J, Dhingra, S, Diaz, J, Di Carlo, I, Di Marzo, F, Di Saverio, S, Dogjani, A, Dorj, G, Dortet, L, Duane, T, Dupont, H, Egiev, V, Eid, H, Elmangory, M, El-Sayed Marei, H, Enani, M, Escandon-Vargas, K, Faro, M, Ferrada, P, Foghetti, D, Foianini, E, Fraga, G, Frattima, S, Gandhi, C, Gattuso, G, Giamarellou, E, Ghnnam, W, Gkiokas, G, Girardis, M, Goff, D, Gomes, C, Gomi, H, Gronerth, R, Guirao, X, Guzman-Blanco, M, Haque, M, Hecker, A, Hell, M, Herzog, T, Hicks, L, Kafka-Ritsch, R, Kao, L, Kanj, S, Kaplan, L, Kapoor, G, Karamarkovic, A, Kashuk, J, Kenig, J, Khamis, F, Khokha, V, Kiguba, R, Kirkpatrick, A, Korner, H, Koike, K, Kok, K, Kon, K, Kong, V, Inaba, K, Ioannidis, O, Isik, A, Iskandar, K, Labbate, M, Labricciosa, F, Lagrou, K, Lagunes, L, Latifi, R, Lasithiotakis, K, Laxminarayan, R, Lee, J, Leone, M, Leppaniemi, A, Li, Y, Liang, S, Liau, K, Litvin, A, Loho, T, Lowman, W, Machain, G, Maier, R, Manzano-Nunez, R, Marinis, A, Marmorale, C, Martin-Loeches, I, Marwah, S, Maseda, E, Mcfarlane, M, De Melo, R, Melotti, M, Memish, Z, Mertz, D, Mesina, C, Menichetti, F, Mishra, S, Montori, G, Moore, E, Moore, F, Naidoo, N, Napolitano, L, Negoi, I, Nicolau, D, Nikolopoulos, I, Nord, C, Ofori-Asenso, R, Olaoye, I, Omari, A, Ordonez, C, Ouadii, M, Ouedraogo, A, Pagani, L, Paiva, J, Parreira, J, Pata, F, Pereira, J, Pereira, N, Petrosillo, N, Picetti, E, Pintar, T, Ponce-De-Leon, A, Popovski, Z, Poulakou, G, Preller, J, Guerrero, A, Pupelis, G, Quiodettis, M, Rawson, T, Reichert, M, Reinhart, K, Rems, M, Rello, J, Rizoli, S, Roberts, J, Rubio-Perez, I, Ruppe, E, Sakakushev, B, Sall, I, Kafil, H, Sanders, J, Sato, N, Sawyer, R, Scalea, T, Scibe, R, Scudeller, L, Lohse, H, Sganga, G, Shafiq, N, Shah, J, Spigaglia, P, Suroowan, S, Tsioutis, C, Sifri, C, Siribumrungwong, B, Sugrue, M, Talving, P, Tan, B, Tarasconi, A, Tascini, C, Tilsed, J, Timsit, J, Tumbarello, M, Trung, N, Ulrych, J, Uranues, S, Velmahos, G, Vereczkei, A, Viale, P, Estape, J, Viscoli, C, Wagenlehner, F, Wright, B, Xiao, Y, Yuan, K, Zachariah, S, Zahar, J, Mergulhao, P, Catena, F, Sartelli M., Kluger Y., Ansaloni L., Carlet J., Brink A., Hardcastle T. C., Khanna A., Chicom-Mefire A., Rodriguez-Bano J., Nathwani D., Mendelson M., Watkins R. R., Pulcini C., Beovic B., May A. K., Itani K. M. F., Mazuski J. E., Fry D. E., Coccolini F., Rasxa K., Montravers P., Eckmann C., Abbo L. M., Abubakar S., Abu-Zidan F. M., Adesunkanmi A. K., Al-Hasan M. N., Althani A. A., Ticas J. E. A., Ansari S., Ansumana R., Da Silva A. R. A., Augustin G., Bala M., Balogh Z. J., Baraket O., Bassetti M., Bellanova G., Beltran M. A., Ben-Ishay O., Biffl W. L., Boermeester M. A., Brecher S. M., Bueno J., Cainzos M. A., Cairns K., Camacho-Ortiz A., Ceresoli M., Chandy S. J., Cherry-Bukowiec J. R., Cirocchi R., Colak E., Corcione A., Cornely O. A., Cortese F., Cui Y., Curcio D., Damaskos D., Dasx K., Delibegovic S., Demetrashvili Z., De Simone B., De Souza H. P., De Waele J., Dhingra S., Diaz J. J., Di Carlo I., Di Marzo F., Di Saverio S., Dogjani A., Dorj G., Dortet L., Duane T. M., Dupont H., Egiev V. N., Eid H. O., Elmangory M., El-Sayed Marei H., Enani M. A., Escandon-Vargas K., Faro M. P., Ferrada P., Foghetti D., Foianini E., Fraga G. P., Frattima S., Gandhi C., Gattuso G., Giamarellou E., Ghnnam W., Gkiokas G., Girardis M., Goff D. A., Gomes C. A., Gomi H., Gronerth R. I. G., Guirao X., Guzman-Blanco M., Haque M., Hecker A., Hell M., Herzog T., Hicks L., Kafka-Ritsch R., Kao L. S., Kanj S. S., Kaplan L. J., Kapoor G., Karamarkovic A., Kashuk J., Kenig J., Khamis F., Khokha V., Kiguba R., Kirkpatrick A. W., Korner H., Koike K., Kok K. Y. Y., Kon K., Kong V., Inaba K., Ioannidis O., Isik A., Iskandar K., Labbate M., Labricciosa F. M., Lagrou K., Lagunes L., Latifi R., Lasithiotakis K., Laxminarayan R., Lee J. G., Leone M., Leppaniemi A., Li Y., Liang S. Y., Liau K. -H., Litvin A., Loho T., Lowman W., Machain G. M., Maier R. V., Manzano-Nunez R., Marinis A., Marmorale C., Martin-Loeches I., Marwah S., Maseda E., McFarlane M., De Melo R. B., Melotti M. R., Memish Z., Mertz D., Mesina C., Menichetti F., Mishra S. K., Montori G., Moore E. E., Moore F. A., Naidoo N., Napolitano L., Negoi I., Nicolau D. P., Nikolopoulos I., Nord C. E., Ofori-Asenso R., Olaoye I., Omari A. H., Ordonez C. A., Ouadii M., Ouedraogo A. -S., Pagani L., Paiva J. A., Parreira J. G., Pata F., Pereira J., Pereira N. R., Petrosillo N., Picetti E., Pintar T., Ponce-De-Leon A., Popovski Z., Poulakou G., Preller J., Guerrero A. P., Pupelis G., Quiodettis M., Rawson T. M., Reichert M., Reinhart K., Rems M., Rello J., Rizoli S., Roberts J., Rubio-Perez I., Ruppe E., Sakakushev B., Sall I., Kafil H. S., Sanders J., Sato N., Sawyer R. G., Scalea T., Scibe R., Scudeller L., Lohse H. S., Sganga G., Shafiq N., Shah J. N., Spigaglia P., Suroowan S., Tsioutis C., Sifri C. D., Siribumrungwong B., Sugrue M., Talving P., Tan B. K., Tarasconi A., Tascini C., Tilsed J., Timsit J. -F., Tumbarello M., Trung N. T., Ulrych J., Uranues S., Velmahos G., Vereczkei A. G., Viale P., Estape J. V., Viscoli C., Wagenlehner F., Wright B. J., Xiao Y., Yuan K. -C., Zachariah S. K., Zahar J. R., Mergulhao P., and Catena F.

Abstract

This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections. As such, it is our intent to raise awareness among healthcare workers and improve antimicrobial prescribing. To facilitate its dissemination, the declaration was translated in different languages.

Published
2017

4. Oral fosfomycin for the treatment of chronic bacterial prostatitis

Author

Karaiskos, I. Galani, L. Sakka, V. Gkoufa, A. Sopilidis, O. Chalikopoulos, D. Alivizatos, G. Giamarellou, E.

Abstract

Background: Chronic bacterial prostatitis (CBP) is a difficult-to-treat infection as only a few antibiotics achieve therapeutic concentrations in the prostate. Data on the efficacy and safety of oral fosfomycin for the treatment of CBP are limited. Objectives: To analyse the efficacy and safety of fosfomycin in CBP due to MDR pathogens. Methods: In a prospective observational study, an oral regimen of 3 g of fosfomycin q24h for 1 week followed by 3 g q48h for a treatment duration of 6-12 weeks was administered. The outcome was clinical and microbiological cure rate at the end of treatment (EOT) and rate of relapse at 3 and 6 months. Results: The study included 44 patients. The most common pathogen was Escherichia coli (66%), followed by Klebsiella spp. (14%) and Enterococcus faecalis (14%). Most strains were MDR (59%) and 23% had an ESBL phenotype; 33 of 44 strains were resistant to fluoroquinolones, but all were susceptible to fosfomycin (median MIC for Gram-negative pathogens 1.5 mg/L). In 25 patients, treatment was administered for 6 weeks, whereas in the remaining 19 patients it was prolonged to 12 weeks based on the presence of calcifications in the prostate. Cure rate was 82% at EOT and 80% and 73% at 3 and 6 months accordingly. Microbiological eradication was achieved in 86% and 77% at EOT and at 6 months, respectively. Failure was observed in 12 patients. The most common adverse event was diarrhoea (18%). Conclusions: Oral fosfomycin, particularly in the era of MDR prevalence, represents an attractive, safe and effective alternative to fluoroquinolones for the treatment of CBP. © 2019 The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.

Published
2019

6. World alliance against antibiotic resistance: The WAAAR declaration against antibiotic resistance

Author

Carlet, J, Aaron, L, Abassi, M, Abbo, L, Aboderin, O, Abraham, E, Abroug, F, Acar, J, Achour, W, Adachi, J, Al-Abri, S, Al-Mousa, H, Albaya-Moreno, A, Alberti, C, Alfandari, S, Alnimr, A, Aranda, C, de Lerma, F, Amer, F, Andremont, A, Angoulvant, F, Anguill, M, Antonelli, M, Antoniadou, E, Arlet, G, Armaganidis, A, Arnera, A, Artigas, A, Attali, C, Auber, F, Aubert, J, Augereau, B, Aupee, M, Bahri, O, Ballereau, F, Bapt, G, Baquero, F, Barkhan, T, Barouti, O, Barthelemy, M, Barton, G, Bastoni, D, Baussier, M, Bavestrello, L, Beger, B, Benenson, S, Bensalem, F, Beraud, G, Bergheau, F, Bernard, G, Berthelot, P, Bertrand, X, Beuhorry-Sassus, F, Beuret, P, Billington, J, Birge, J, Biscardi, S, Blanch, L, Blanchard, H, Bleck, T, Blondeau, J, Blot, F, Borgey, F, Bousquet-Melou, A, Brami, J, Brard, C, Bretagne, S, Bretonniere, C, Brink, A, Brown, S, Bruant-Rodier, C, Brun-Buisson, C, Bruneel, F, de Carvalho, F, Buhot, C, Bukharie, H, Cabie, A, Calandra, T, Caniaux, I, Canica, M, Canton, R, Carenco, P, Carlet, C, Carlet, F, Carlet, R, Cars, O, Cassiano-Neves, M, Castan, B, Castellan, V, Cazenave-Roblot, F, Ceretti, A, Chakarian, J, Chalumeau-Lemoine, L, Chandy, J, Chanfreau, B, Chastre, J, Chausset, R, Chavanet, P, Cheadle, W, Chiche, J, Chidiac, C, Chosidow, O, Chueca, N, Cohen, J, Cohen, R, Collignon, P, Collot, F, Coloby, P, Conly, J, Cordero, C, Cordonnier, C, Corso, A, Cosgrove, S, Courcol, R, Crane, S, Craven, D, Crespin, A, Cyrillo, M, Danin, P, Waele, J, Dellamonica, P, Patchen Dellinger, E, Dellinger, P, Delmont, J, Denes, E, Dimopoulos, G, Drekonja, D, Mansilla, A, Druais, P, Dufour-Pierrat, S, Dumartin, C, Dunser, M, Dupont, M, Durlach, R, Dyar, O, Echaniz, G, Edelstein, P, Eggimann, P, Elghonemi, M, Elmdaghri, N, Elsaid, R, Elsokari, R, Engelhard, D, Fabry, J, Farmer, C, Fernandez, J, Finfer, S, Finn, P, Fjeldsted, K, Floret, D, Flozaro, F, Foegle, J, Forceville, X, Fournier, S, Frachon, I, Friedrich, A, Funuel, P, Gaillard, D, Gaillat, J, Galperine, T, Gambarotto, K, Garo, B, Garrouste-Orgeas, M, Gastemeier, P, Gauchot, J, Gauzit, R, Gavazzi, G, Gazagne, L, Gerberding, J, Ghafur, A, Giamarellos-Bourboulis, E, Giamarellou, E, Giard, M, Gilchrist, M, Gilquin, J, Gilsanz, F, Gniadkowski, M, Gogos, C, Goldman, D, Gordon, F, Gottlieb, T, Gould, I, Gouveia, J, Grant, J, Grason, L, Greder, A, Grundman, H, Guaguere, E, Gueroult-Locher, G, Guery, B, Guidet, B, Guignabert, C, Gupta, P, Gupta, S, Gurjar, M, Guzman, M, Hajjar, J, Hammad, N, Hammerum, A, Hanberger, H, Hanke, R, Harbarth, S, Harel, A, Heisbourg, E, Hermes, I, Hermet, J, Hirschel, B, Hoen, B, Hollis, A, Honghong, X, Hooper, D, Horcajada, J, Housset, B, Hryniewicz, W, Hsu, L, Huang, S, Hughes, J, Hunault, J, Jakobsen, L, Jalil, N, Jansens, H, Jarlier, V, Jarvis, W, Jean, D, Jereb, M, Johnson, J, Joly-Guillou, M, Jonquet, O, Kac, G, Kaddu-Mulindwa, D, Kaku, M, Kilani, B, Kim, E, Gazard, D, Klugman, K, Klutts, S, Kluytmans, J, Kollef, M, Koulenti, D, Kresken, M, Lacoin, F, Lajonchere, J, Landgraf, N, Larroussinie, G, Laterre, P, Lavenaire, A, Lavigne, T, Laxminarayan, R, Le, T, Leblanc-Jouffre, F, Lee, N, Lehiani, O, Lelouet, H, Lemanach-Kergueris, F, Lepape, A, Leroy, J, Lescure, X, Levy, M, Levy-Hara, G, Lin, L, Lipman, J, Livartowski, J, Looke, D, Cardozo, F, Medrano, F, Lotthe, A, Lucet, J, Lupande, D, Madec, J, Mainardi, J, Maiylagan, S, Mancebo, J, Mansour-Adeoti, F, Maravi, E, Marchou, B, Marciniuk, D, Marshall, J, Martin, C, Martin, D, Martinez-Martinez, L, Martinot, A, Maseda, E, Matamis, D, Matheron, S, Matos, R, Matthews, M, May, T, Mayet, T, Mcgowan, J, Mehtar, S, Teles, J, Mendelson, M, Michelet, C, Mifsud, A, Mikaszewska-Sokolewicz, M, Minion, J, Miquel, C, Mira, J, Miro, J, Misset, B, Monot, J, Montravers, P, Mootien, J, Moreno, R, Morris, A, Moulin, G, Mourlan, C, Mouthon, G, Mowafy, W, Muhl, E, Muruganathan, A, Mushira, E, N'Doye, B, Nana, A, Niederman, M, Nitenberg, G, Nordman, P, Novira, A, Nowak, C, Okeke, I, Olaechea, P, Omar, A, Opal, S, Leyba, C, Oudega, B, Oziol, E, Page, B, Paiva, J, Palmer, L, Palomar-Martinez, M, Parneix, P, de la Garanderie, D, Perencevich, E, Perl, T, Perronne, C, Peters, G, Peters, M, Peyramond, D, Philippart, F, Pittet, D, Pittet, J, Plesiat, P, Pletz, M, Ploy, M, Pospisil, F, Pouedras, P, Poulakou, G, Poursinoff, A, Pronovost, P, Pulcini, C, Puoti, M, Puvanendiram, S, Quintel, M, Rabaud, C, Rambaud, C, Ramos, H, Rassla, O, Raymond, J, Regnier, B, Reinhart, K, Condomines, J, Revil, J, Riche, A, Richman, P, Richmann, R, Rodriguez, V, Rodriguez-Bano, J, Romain, O, Romand, K, Rossines, E, Rothan-Tondeur, M, Rousselot, J, Rubinstein, E, Rudnov, V, Saini, N, Salmon, D, Salomao, R, Garcia, M, Santos-Bouza, A, Saux, M, Savey, A, Saxinger, L, Schlemmer, B, Schmit, J, Schneider, D, Schoemaker, J, Singh, S, Sole-Violan, J, Soto, S, Stahl, J, Stoclin, A, Tabah, A, Tabut, J, Tambyah, P, Tamion, F, Tarr, P, Tattevin, P, Tenover, F, Terzi, N, Lecompte, M, Theodore, J, Thevenin, D, Thevenot, P, Thiriet, L, Thompson, C, Thurn, J, Tillotson, G, Tiouiri, H, Torres, A, Tremolieres, F, Troadec, M, Umar, R, Upham, G, Urban, C, Vaarten, J, Valla, D, Van Der Mee-Marquet, N, Van der Meer, J, Van Der Poll, T, Vancel, J, Vanhems, P, Varin, R, Varon, E, Vaughan, D, Veilly, M, Vijayakumar, K, Villanueva, A, Vincent, J, Vitrat, V, Voss, A, Wachter, R, Walsh, T, Wark, P, Waterer, G, Wegener, H, Weinbreck, P, Weinstein, R, Weissman, S, Wiener-Kronish, J, Wilmer, A, Wyplosz, B, Yacoub-Agha, I, Young, M, Yusuf, I, Zein, E, Zhanel, G, Zinner, S, Zoungrana, J, Zubareva, N, Carlet J., Aaron L., Abassi M. S., Abbo L., Aboderin O., Abraham E., Abroug F., Acar J., Achour W., Adachi J., Al-Abri S., Al-Mousa H., Albaya-Moreno A., Alberti C., Alfandari S., Alnimr A., Aranda C. A., de Lerma F. A., Amer F., Andremont A., Angoulvant F., Anguill M., Antonelli M., Antoniadou E., Arlet G., Armaganidis A., Arnera A., Artigas A., Attali C., Auber F., Aubert J. -P., Augereau B., Aupee M., Bahri O., Ballereau F., Bapt G., Baquero F., Barkhan T., Barouti O., Barthelemy M. -A., Barton G., Bastoni D., Baussier M., Bavestrello L., Beger B., Benenson S., Bensalem F., Beraud G., Bergheau F., Bernard G., Berthelot P., Bertrand X., Beuhorry-Sassus F., Beuret P., Billington J., Birge J., Biscardi S., Blanch L., Blanchard H., Bleck T., Blondeau J., Blot F., Borgey F., Bousquet-Melou A., Brami J., Brard C., Bretagne S., Bretonniere C., Brink A., Brown S., Bruant-Rodier C., Brun-Buisson C., Bruneel F., de Carvalho F. B., Buhot C., Bukharie H., Cabie A., Calandra T., Caniaux I., Canica M., Canton R., Carenco P., Carlet C., Carlet F., Carlet R., Cars O., Cassiano-Neves M., Castan B., Castellan V., Cazenave-Roblot F., Ceretti A. -M., Chakarian J. -C., Chalumeau-Lemoine L., Chandy J., Chanfreau B., Chastre J., Chausset R., Chavanet P., Cheadle W., Chiche J. -D., Chidiac C., Chosidow O., Chueca N., Cohen J., Cohen R., Collignon P., Collot F., Coloby P., Conly J., Cordero C., Cordonnier C., Corso A., Cosgrove S., Courcol R., Crane S., Craven D., Crespin A., Cyrillo M., Danin P. -E., Waele J. D., Dellamonica P., Patchen Dellinger E., Dellinger P., Delmont J., Denes E., Dimopoulos G., Drekonja D., Mansilla A. D., Druais P. -L., Dufour-Pierrat S., Dumartin C., Dunser M., Dupont M., Durlach R., Dyar O., Echaniz G., Edelstein P., Eggimann P., Elghonemi M., Elmdaghri N., Elsaid R., Elsokari R., Engelhard D., Fabry J., Farmer C., Fernandez J., Finfer S., Finn P., Fjeldsted K., Floret D., Flozaro F., Foegle J., Forceville X., Fournier S., Frachon I., Friedrich A., Funuel P., Gaillard D., Gaillat J., Galperine T., Gambarotto K., Garo B., Garrouste-Orgeas M., Gastemeier P., Gauchot J. -Y., Gauzit R., Gavazzi G., Gazagne L., Gerberding J., Ghafur A., Giamarellos-Bourboulis E., Giamarellou E., Giard M., Gilchrist M., Gilquin J., Gilsanz F., Gniadkowski M., Gogos C., Goldman D., Gordon F., Gottlieb T., Gould I., Gouveia J., Grant J., Grason L., Greder A., Grundman H., Guaguere E., Gueroult-Locher G., Guery B., Guidet B., Guignabert C., Gupta P., Gupta S., Gurjar M., Guzman M., Hajjar J., Hammad N., Hammerum A., Hanberger H., Hanke R., Harbarth S., Harel A., Heisbourg E., Hermes I., Hermet J. -P., Hirschel B., Hoen B., Hollis A., Honghong X., Hooper D., Horcajada J. P., Housset B., Hryniewicz W., Hsu L. Y., Huang S., Hughes J., Hunault J. -L., Jakobsen L., Jalil N., Jansens H., Jarlier V., Jarvis W., Jean D., Jereb M., Johnson J., Joly-Guillou M. -L., Jonquet O., Kac G., Kaddu-Mulindwa D., Kaku M., Kilani B., Kim E. -C., Gazard D. K., Klugman K., Klutts S., Kluytmans J., Kollef M., Koulenti D., Kresken M., Lacoin F., Lajonchere J. -P., Landgraf N., Larroussinie G., Laterre P. -F., Lavenaire A. -M., Lavigne T., Laxminarayan R., Le T. A. T., Leblanc-Jouffre F., Lee N. Y., Lehiani O., Lelouet H., Lemanach-Kergueris F., Lepape A., Leroy J., Lescure X., Levy M., Levy-Hara G., Lin L. M., Lipman J., Livartowski J., Looke D., Cardozo F. L. L., Medrano F. L., Lotthe A., Lucet J. C., Lupande D., Madec J. -Y., Mainardi J. -L., Maiylagan S., Mancebo J., Mansour-Adeoti F., Maravi E., Marchou B., Marciniuk D., Marshall J., Martin C., Martin D., Martinez-Martinez L., Martinot A., Maseda E., Matamis D., Matheron S., Matos R., Matthews M., May T., Mayet T., McGowan J., Mehtar S., Teles J. M. M., Mendelson M., Michelet C., Mifsud A., Mikaszewska-Sokolewicz M., Minion J., Miquel C., Mira J. -P., Miro J., Misset B., Monot J. -J., Montravers P., Mootien J., Moreno R., Morris A., Moulin G., Mourlan C., Mouthon G., Mowafy W., Muhl E., Muruganathan A., Mushira E., N'Doye B., Nana A., Niederman M., Nitenberg G., Nordman P., Novira A., Nowak C., Okeke I., Olaechea P. M., Omar A., Opal S., Leyba C. O., Oudega B., Oziol E., Page B., Paiva J. A., Palmer L., Palomar-Martinez M., Parneix P., de la Garanderie D. P., Perencevich E., Perl T., Perronne C., Peters G., Peters M., Peyramond D., Philippart F., Pittet D., Pittet J. -F., Plesiat P., Pletz M., Ploy M. -C., Pospisil F., Pouedras P., Poulakou G., Poursinoff A., Pronovost P., Pulcini C., Puoti M., Puvanendiram S., Quintel M., Rabaud C., Rambaud C., Ramos H., Rassla O., Raymond J., Regnier B., Reinhart K., Condomines J. R., Revil J. -C., Riche A., Richman P., Richmann R., Rodriguez V., Rodriguez-Bano J., Romain O., Romand K., Rossines E., Rothan-Tondeur M. I., Rousselot J. -F., Rubinstein E., Rudnov V., Saini N., Salmon D., Salomao R., Garcia M. S., Santos-Bouza A., Saux M. -C., Savey A., Saxinger L., Schlemmer B., Schmit J. -L., Schneider D., Schoemaker J., Singh S., Sole-Violan J., Soto S., Stahl J. -P., Stoclin A., Tabah A., Tabut J. -P., Tambyah P. A., Tamion F., Tarr P., Tattevin P., Tenover F., Terzi N., Lecompte M. T., Theodore J., Thevenin D., Thevenot P., Thiriet L., Thompson C., Thurn J., Tillotson G., Tiouiri H., Torres A., Tremolieres F., Troadec M., Umar R., Upham G., Urban C., Vaarten J., Valla D., Van Der Mee-Marquet N., Van der Meer J., Van Der Poll T., Vancel J., Vanhems P., Varin R., Varon E., Vaughan D., Veilly M., Vijayakumar K., Villanueva A., Vincent J. -L., Vitrat V., Voss A., Wachter R., Walsh T., Wark P., Waterer G., Wegener H. C., Weinbreck P., Weinstein R., Weissman S., Wiener-Kronish J., Wilmer A., Wyplosz B., Yacoub-Agha I., Young M., Yusuf I., Zein E., Zhanel G., Zinner S., Zoungrana J., Zubareva N., Carlet, J, Aaron, L, Abassi, M, Abbo, L, Aboderin, O, Abraham, E, Abroug, F, Acar, J, Achour, W, Adachi, J, Al-Abri, S, Al-Mousa, H, Albaya-Moreno, A, Alberti, C, Alfandari, S, Alnimr, A, Aranda, C, de Lerma, F, Amer, F, Andremont, A, Angoulvant, F, Anguill, M, Antonelli, M, Antoniadou, E, Arlet, G, Armaganidis, A, Arnera, A, Artigas, A, Attali, C, Auber, F, Aubert, J, Augereau, B, Aupee, M, Bahri, O, Ballereau, F, Bapt, G, Baquero, F, Barkhan, T, Barouti, O, Barthelemy, M, Barton, G, Bastoni, D, Baussier, M, Bavestrello, L, Beger, B, Benenson, S, Bensalem, F, Beraud, G, Bergheau, F, Bernard, G, Berthelot, P, Bertrand, X, Beuhorry-Sassus, F, Beuret, P, Billington, J, Birge, J, Biscardi, S, Blanch, L, Blanchard, H, Bleck, T, Blondeau, J, Blot, F, Borgey, F, Bousquet-Melou, A, Brami, J, Brard, C, Bretagne, S, Bretonniere, C, Brink, A, Brown, S, Bruant-Rodier, C, Brun-Buisson, C, Bruneel, F, de Carvalho, F, Buhot, C, Bukharie, H, Cabie, A, Calandra, T, Caniaux, I, Canica, M, Canton, R, Carenco, P, Carlet, C, Carlet, F, Carlet, R, Cars, O, Cassiano-Neves, M, Castan, B, Castellan, V, Cazenave-Roblot, F, Ceretti, A, Chakarian, J, Chalumeau-Lemoine, L, Chandy, J, Chanfreau, B, Chastre, J, Chausset, R, Chavanet, P, Cheadle, W, Chiche, J, Chidiac, C, Chosidow, O, Chueca, N, Cohen, J, Cohen, R, Collignon, P, Collot, F, Coloby, P, Conly, J, Cordero, C, Cordonnier, C, Corso, A, Cosgrove, S, Courcol, R, Crane, S, Craven, D, Crespin, A, Cyrillo, M, Danin, P, Waele, J, Dellamonica, P, Patchen Dellinger, E, Dellinger, P, Delmont, J, Denes, E, Dimopoulos, G, Drekonja, D, Mansilla, A, Druais, P, Dufour-Pierrat, S, Dumartin, C, Dunser, M, Dupont, M, Durlach, R, Dyar, O, Echaniz, G, Edelstein, P, Eggimann, P, Elghonemi, M, Elmdaghri, N, Elsaid, R, Elsokari, R, Engelhard, D, Fabry, J, Farmer, C, Fernandez, J, Finfer, S, Finn, P, Fjeldsted, K, Floret, D, Flozaro, F, Foegle, J, Forceville, X, Fournier, S, Frachon, I, Friedrich, A, Funuel, P, Gaillard, D, Gaillat, J, Galperine, T, Gambarotto, K, Garo, B, Garrouste-Orgeas, M, Gastemeier, P, Gauchot, J, Gauzit, R, Gavazzi, G, Gazagne, L, Gerberding, J, Ghafur, A, Giamarellos-Bourboulis, E, Giamarellou, E, Giard, M, Gilchrist, M, Gilquin, J, Gilsanz, F, Gniadkowski, M, Gogos, C, Goldman, D, Gordon, F, Gottlieb, T, Gould, I, Gouveia, J, Grant, J, Grason, L, Greder, A, Grundman, H, Guaguere, E, Gueroult-Locher, G, Guery, B, Guidet, B, Guignabert, C, Gupta, P, Gupta, S, Gurjar, M, Guzman, M, Hajjar, J, Hammad, N, Hammerum, A, Hanberger, H, Hanke, R, Harbarth, S, Harel, A, Heisbourg, E, Hermes, I, Hermet, J, Hirschel, B, Hoen, B, Hollis, A, Honghong, X, Hooper, D, Horcajada, J, Housset, B, Hryniewicz, W, Hsu, L, Huang, S, Hughes, J, Hunault, J, Jakobsen, L, Jalil, N, Jansens, H, Jarlier, V, Jarvis, W, Jean, D, Jereb, M, Johnson, J, Joly-Guillou, M, Jonquet, O, Kac, G, Kaddu-Mulindwa, D, Kaku, M, Kilani, B, Kim, E, Gazard, D, Klugman, K, Klutts, S, Kluytmans, J, Kollef, M, Koulenti, D, Kresken, M, Lacoin, F, Lajonchere, J, Landgraf, N, Larroussinie, G, Laterre, P, Lavenaire, A, Lavigne, T, Laxminarayan, R, Le, T, Leblanc-Jouffre, F, Lee, N, Lehiani, O, Lelouet, H, Lemanach-Kergueris, F, Lepape, A, Leroy, J, Lescure, X, Levy, M, Levy-Hara, G, Lin, L, Lipman, J, Livartowski, J, Looke, D, Cardozo, F, Medrano, F, Lotthe, A, Lucet, J, Lupande, D, Madec, J, Mainardi, J, Maiylagan, S, Mancebo, J, Mansour-Adeoti, F, Maravi, E, Marchou, B, Marciniuk, D, Marshall, J, Martin, C, Martin, D, Martinez-Martinez, L, Martinot, A, Maseda, E, Matamis, D, Matheron, S, Matos, R, Matthews, M, May, T, Mayet, T, Mcgowan, J, Mehtar, S, Teles, J, Mendelson, M, Michelet, C, Mifsud, A, Mikaszewska-Sokolewicz, M, Minion, J, Miquel, C, Mira, J, Miro, J, Misset, B, Monot, J, Montravers, P, Mootien, J, Moreno, R, Morris, A, Moulin, G, Mourlan, C, Mouthon, G, Mowafy, W, Muhl, E, Muruganathan, A, Mushira, E, N'Doye, B, Nana, A, Niederman, M, Nitenberg, G, Nordman, P, Novira, A, Nowak, C, Okeke, I, Olaechea, P, Omar, A, Opal, S, Leyba, C, Oudega, B, Oziol, E, Page, B, Paiva, J, Palmer, L, Palomar-Martinez, M, Parneix, P, de la Garanderie, D, Perencevich, E, Perl, T, Perronne, C, Peters, G, Peters, M, Peyramond, D, Philippart, F, Pittet, D, Pittet, J, Plesiat, P, Pletz, M, Ploy, M, Pospisil, F, Pouedras, P, Poulakou, G, Poursinoff, A, Pronovost, P, Pulcini, C, Puoti, M, Puvanendiram, S, Quintel, M, Rabaud, C, Rambaud, C, Ramos, H, Rassla, O, Raymond, J, Regnier, B, Reinhart, K, Condomines, J, Revil, J, Riche, A, Richman, P, Richmann, R, Rodriguez, V, Rodriguez-Bano, J, Romain, O, Romand, K, Rossines, E, Rothan-Tondeur, M, Rousselot, J, Rubinstein, E, Rudnov, V, Saini, N, Salmon, D, Salomao, R, Garcia, M, Santos-Bouza, A, Saux, M, Savey, A, Saxinger, L, Schlemmer, B, Schmit, J, Schneider, D, Schoemaker, J, Singh, S, Sole-Violan, J, Soto, S, Stahl, J, Stoclin, A, Tabah, A, Tabut, J, Tambyah, P, Tamion, F, Tarr, P, Tattevin, P, Tenover, F, Terzi, N, Lecompte, M, Theodore, J, Thevenin, D, Thevenot, P, Thiriet, L, Thompson, C, Thurn, J, Tillotson, G, Tiouiri, H, Torres, A, Tremolieres, F, Troadec, M, Umar, R, Upham, G, Urban, C, Vaarten, J, Valla, D, Van Der Mee-Marquet, N, Van der Meer, J, Van Der Poll, T, Vancel, J, Vanhems, P, Varin, R, Varon, E, Vaughan, D, Veilly, M, Vijayakumar, K, Villanueva, A, Vincent, J, Vitrat, V, Voss, A, Wachter, R, Walsh, T, Wark, P, Waterer, G, Wegener, H, Weinbreck, P, Weinstein, R, Weissman, S, Wiener-Kronish, J, Wilmer, A, Wyplosz, B, Yacoub-Agha, I, Young, M, Yusuf, I, Zein, E, Zhanel, G, Zinner, S, Zoungrana, J, Zubareva, N, Carlet J., Aaron L., Abassi M. S., Abbo L., Aboderin O., Abraham E., Abroug F., Acar J., Achour W., Adachi J., Al-Abri S., Al-Mousa H., Albaya-Moreno A., Alberti C., Alfandari S., Alnimr A., Aranda C. A., de Lerma F. A., Amer F., Andremont A., Angoulvant F., Anguill M., Antonelli M., Antoniadou E., Arlet G., Armaganidis A., Arnera A., Artigas A., Attali C., Auber F., Aubert J. -P., Augereau B., Aupee M., Bahri O., Ballereau F., Bapt G., Baquero F., Barkhan T., Barouti O., Barthelemy M. -A., Barton G., Bastoni D., Baussier M., Bavestrello L., Beger B., Benenson S., Bensalem F., Beraud G., Bergheau F., Bernard G., Berthelot P., Bertrand X., Beuhorry-Sassus F., Beuret P., Billington J., Birge J., Biscardi S., Blanch L., Blanchard H., Bleck T., Blondeau J., Blot F., Borgey F., Bousquet-Melou A., Brami J., Brard C., Bretagne S., Bretonniere C., Brink A., Brown S., Bruant-Rodier C., Brun-Buisson C., Bruneel F., de Carvalho F. B., Buhot C., Bukharie H., Cabie A., Calandra T., Caniaux I., Canica M., Canton R., Carenco P., Carlet C., Carlet F., Carlet R., Cars O., Cassiano-Neves M., Castan B., Castellan V., Cazenave-Roblot F., Ceretti A. -M., Chakarian J. -C., Chalumeau-Lemoine L., Chandy J., Chanfreau B., Chastre J., Chausset R., Chavanet P., Cheadle W., Chiche J. -D., Chidiac C., Chosidow O., Chueca N., Cohen J., Cohen R., Collignon P., Collot F., Coloby P., Conly J., Cordero C., Cordonnier C., Corso A., Cosgrove S., Courcol R., Crane S., Craven D., Crespin A., Cyrillo M., Danin P. -E., Waele J. D., Dellamonica P., Patchen Dellinger E., Dellinger P., Delmont J., Denes E., Dimopoulos G., Drekonja D., Mansilla A. D., Druais P. -L., Dufour-Pierrat S., Dumartin C., Dunser M., Dupont M., Durlach R., Dyar O., Echaniz G., Edelstein P., Eggimann P., Elghonemi M., Elmdaghri N., Elsaid R., Elsokari R., Engelhard D., Fabry J., Farmer C., Fernandez J., Finfer S., Finn P., Fjeldsted K., Floret D., Flozaro F., Foegle J., Forceville X., Fournier S., Frachon I., Friedrich A., Funuel P., Gaillard D., Gaillat J., Galperine T., Gambarotto K., Garo B., Garrouste-Orgeas M., Gastemeier P., Gauchot J. -Y., Gauzit R., Gavazzi G., Gazagne L., Gerberding J., Ghafur A., Giamarellos-Bourboulis E., Giamarellou E., Giard M., Gilchrist M., Gilquin J., Gilsanz F., Gniadkowski M., Gogos C., Goldman D., Gordon F., Gottlieb T., Gould I., Gouveia J., Grant J., Grason L., Greder A., Grundman H., Guaguere E., Gueroult-Locher G., Guery B., Guidet B., Guignabert C., Gupta P., Gupta S., Gurjar M., Guzman M., Hajjar J., Hammad N., Hammerum A., Hanberger H., Hanke R., Harbarth S., Harel A., Heisbourg E., Hermes I., Hermet J. -P., Hirschel B., Hoen B., Hollis A., Honghong X., Hooper D., Horcajada J. P., Housset B., Hryniewicz W., Hsu L. Y., Huang S., Hughes J., Hunault J. -L., Jakobsen L., Jalil N., Jansens H., Jarlier V., Jarvis W., Jean D., Jereb M., Johnson J., Joly-Guillou M. -L., Jonquet O., Kac G., Kaddu-Mulindwa D., Kaku M., Kilani B., Kim E. -C., Gazard D. K., Klugman K., Klutts S., Kluytmans J., Kollef M., Koulenti D., Kresken M., Lacoin F., Lajonchere J. -P., Landgraf N., Larroussinie G., Laterre P. -F., Lavenaire A. -M., Lavigne T., Laxminarayan R., Le T. A. T., Leblanc-Jouffre F., Lee N. Y., Lehiani O., Lelouet H., Lemanach-Kergueris F., Lepape A., Leroy J., Lescure X., Levy M., Levy-Hara G., Lin L. M., Lipman J., Livartowski J., Looke D., Cardozo F. L. L., Medrano F. L., Lotthe A., Lucet J. C., Lupande D., Madec J. -Y., Mainardi J. -L., Maiylagan S., Mancebo J., Mansour-Adeoti F., Maravi E., Marchou B., Marciniuk D., Marshall J., Martin C., Martin D., Martinez-Martinez L., Martinot A., Maseda E., Matamis D., Matheron S., Matos R., Matthews M., May T., Mayet T., McGowan J., Mehtar S., Teles J. M. M., Mendelson M., Michelet C., Mifsud A., Mikaszewska-Sokolewicz M., Minion J., Miquel C., Mira J. -P., Miro J., Misset B., Monot J. -J., Montravers P., Mootien J., Moreno R., Morris A., Moulin G., Mourlan C., Mouthon G., Mowafy W., Muhl E., Muruganathan A., Mushira E., N'Doye B., Nana A., Niederman M., Nitenberg G., Nordman P., Novira A., Nowak C., Okeke I., Olaechea P. M., Omar A., Opal S., Leyba C. O., Oudega B., Oziol E., Page B., Paiva J. A., Palmer L., Palomar-Martinez M., Parneix P., de la Garanderie D. P., Perencevich E., Perl T., Perronne C., Peters G., Peters M., Peyramond D., Philippart F., Pittet D., Pittet J. -F., Plesiat P., Pletz M., Ploy M. -C., Pospisil F., Pouedras P., Poulakou G., Poursinoff A., Pronovost P., Pulcini C., Puoti M., Puvanendiram S., Quintel M., Rabaud C., Rambaud C., Ramos H., Rassla O., Raymond J., Regnier B., Reinhart K., Condomines J. R., Revil J. -C., Riche A., Richman P., Richmann R., Rodriguez V., Rodriguez-Bano J., Romain O., Romand K., Rossines E., Rothan-Tondeur M. I., Rousselot J. -F., Rubinstein E., Rudnov V., Saini N., Salmon D., Salomao R., Garcia M. S., Santos-Bouza A., Saux M. -C., Savey A., Saxinger L., Schlemmer B., Schmit J. -L., Schneider D., Schoemaker J., Singh S., Sole-Violan J., Soto S., Stahl J. -P., Stoclin A., Tabah A., Tabut J. -P., Tambyah P. A., Tamion F., Tarr P., Tattevin P., Tenover F., Terzi N., Lecompte M. T., Theodore J., Thevenin D., Thevenot P., Thiriet L., Thompson C., Thurn J., Tillotson G., Tiouiri H., Torres A., Tremolieres F., Troadec M., Umar R., Upham G., Urban C., Vaarten J., Valla D., Van Der Mee-Marquet N., Van der Meer J., Van Der Poll T., Vancel J., Vanhems P., Varin R., Varon E., Vaughan D., Veilly M., Vijayakumar K., Villanueva A., Vincent J. -L., Vitrat V., Voss A., Wachter R., Walsh T., Wark P., Waterer G., Wegener H. C., Weinbreck P., Weinstein R., Weissman S., Wiener-Kronish J., Wilmer A., Wyplosz B., Yacoub-Agha I., Young M., Yusuf I., Zein E., Zhanel G., Zinner S., Zoungrana J., and Zubareva N.

Abstract

We must change how antibiotics are used and adopt proactive strategies, similar to those used to save endangered species. Preservation of the efficacy of antibiotics and to stabilization of antibiotic-susceptible bacterial ecosystems should be global goals. (C) 2014 Elsevier Espana, S.L.U. and SEMICYUC. All rights reserved.

Published
2015

8. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

Author

Sartelli, M. Kluger, Y. Ansaloni, L. Carlet, J. Brink, A. Hardcastle, T.C. Khanna, A. Chicom-Mefire, A. Rodríguez-Baño, J. Nathwani, D. Mendelson, M. Watkins, R.R. Pulcini, C. Beović, B. May, A.K. Itani, K.M.F. Mazuski, J.E. Fry, D.E. Coccolini, F. Rasxa, K. Montravers, P. Eckmann, C. Abbo, L.M. Abubakar, S. Abu-Zidan, F.M. Adesunkanmi, A.K. Al-Hasan, M.N. Althani, A.A. Ticas, J.E.A. Ansari, S. Ansumana, R. Da Silva, A.R.A. Augustin, G. Bala, M. Balogh, Z.J. Baraket, O. Bassetti, M. Bellanova, G. Beltran, M.A. Ben-Ishay, O. Biffl, W.L. Boermeester, M.A. Brecher, S.M. Bueno, J. Cainzos, M.A. Cairns, K. Camacho-Ortiz, A. Ceresoli, M. Chandy, S.J. Cherry-Bukowiec, J.R. Cirocchi, R. Colak, E. Corcione, A. Cornely, O.A. Cortese, F. Cui, Y. Curcio, D. Damaskos, D. Dasx, K. Delibegovic, S. Demetrashvili, Z. De Simone, B. De Souza, H.P. De Waele, J. Dhingra, S. Diaz, J.J. Di Carlo, I. Di Marzo, F. Di Saverio, S. Dogjani, A. Dorj, G. Dortet, L. Duane, T.M. Dupont, H. Egiev, V.N. Eid, H.O. Elmangory, M. El-Sayed Marei, H. Enani, M.A. Escandón-Vargas, K. Faro, M.P., Jr. Ferrada, P. Foghetti, D. Foianini, E. Fraga, G.P. Frattima, S. Gandhi, C. Gattuso, G. Giamarellou, E. Ghnnam, W. Gkiokas, G. Girardis, M. Goff, D.A. Gomes, C.A. Gomi, H. Gronerth, R.I.G. Guirao, X. Guzman-Blanco, M. Haque, M. Hecker, A. Hell, M. Herzog, T. Hicks, L. Kafka-Ritsch, R. Kao, L.S. Kanj, S.S. Kaplan, L.J. Kapoor, G. Karamarkovic, A. Kashuk, J. Kenig, J. Khamis, F. Khokha, V. Kiguba, R. Kirkpatrick, A.W. Kørner, H. Koike, K. Kok, K.Y.Y. Kon, K. Kong, V. Inaba, K. Ioannidis, O. Isik, A. Iskandar, K. Labbate, M. Labricciosa, F.M. Lagrou, K. Lagunes, L. Latifi, R. Lasithiotakis, K. Laxminarayan, R. Lee, J.G. Leone, M. Leppäniemi, A. Li, Y. Liang, S.Y. Liau, K.-H. Litvin, A. Loho, T. Lowman, W. Machain, G.M. Maier, R.V. Manzano-Nunez, R. Marinis, A. Marmorale, C. Martin-Loeches, I. Marwah, S. Maseda, E. McFarlane, M. De Melo, R.B. Melotti, M.R. Memish, Z. Mertz, D. Mesina, C. Menichetti, F. Mishra, S.K. Montori, G. Moore, E.E. Moore, F.A. Naidoo, N. Napolitano, L. Negoi, I. Nicolau, D.P. Nikolopoulos, I. Nord, C.E. Ofori-Asenso, R. Olaoye, I. Omari, A.H. Ordoñez, C.A. Ouadii, M. Ouedraogo, A.-S. Pagani, L. Paiva, J.A. Parreira, J.G. Pata, F. Pereira, J. Pereira, N.R. Petrosillo, N. Picetti, E. Pintar, T. Ponce-De-Leon, A. Popovski, Z. Poulakou, G. Preller, J. Guerrero, A.P. Pupelis, G. Quiodettis, M. Rawson, T.M. Reichert, M. Reinhart, K. Rems, M. Rello, J. Rizoli, S. Roberts, J. Rubio-Perez, I. Ruppé, E. Sakakushev, B. Sall, I. Kafil, H.S. Sanders, J. Sato, N. Sawyer, R.G. Scalea, T. Scibé, R. Scudeller, L. Lohse, H.S. Sganga, G. Shafiq, N. Shah, J.N. Spigaglia, P. Suroowan, S. Tsioutis, C. Sifri, C.D. Siribumrungwong, B. Sugrue, M. Talving, P. Tan, B.K. Tarasconi, A. Tascini, C. Tilsed, J. Timsit, J.-F. Tumbarello, M. Trung, N.T. Ulrych, J. Uranues, S. Velmahos, G. Vereczkei, A.G. Viale, P. Estape, J.V. Viscoli, C. Wagenlehner, F. Wright, B.J. Xiao, Y. Yuan, K.-C. Zachariah, S.K. Zahar, J.R. Mergulhão, P. Catena, F.

Abstract

This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections. As such, it is our intent to raise awareness among healthcare workers and improve antimicrobial prescribing. To facilitate its dissemination, the declaration was translated in different languages. © Copyright 2017, Mary Ann Liebert, Inc.

Published
2017

10. Mutations associated with genotypic resistance to antiretroviral therapy in treatment naïve HIV-1 infected patients in Greece

Author

Magiorkinis, E. Paraskevis, D. Magiorkinis, G. Chryssou, S. Chini, M. Lazanas, M. Paparizos, V. Saroglou, G. Antoniadou, A. Giamarellou, E. Karafoulidou, A. Hatzakis, A.

Abstract

The widespread use of antiviral drugs against HIV has increased the prevalence of HIV-1 resistant strains among naïve individuals due to transmission of resistant strains. The purpose of this study was to investigate the presence of HIV-1 strains harboring resistance mutations in naïve patients in Greece. Blood samples were collected from 25 individuals. The DNA sequence of protease and partial reverse transcriptase regions (codons 41-223) were obtained by direct sequencing. Our results showed the absence of any primary resistance mutations in the study population. However, we were able to identify high prevalence of sequence polymorphisms at positions in reverse transcriptase region associated mainly with resistance to NNRTIs. Moreover, in protease region several secondary mutations were detected, suggesting the higher genetic variability of this region. The clinical significance of the polymorphisms associated with reduced susceptibility to NNRTIs remains to be clarified. © 2002 Elsevier Science B.V. All rights reserved.

Published
2002

12. Knowledge regarding assessment of sepsis among Greek nurses.

Author

Stamataki, P, Papazafiropoulou, A, Kalaitzi, S, Sarafis, P, Kagialari, M, Adamou, E, Diplou, A, Stravopodis, G, Papadimitriou, A, Giamarellou, E, and Karaiskou, A

Subjects
ACADEMIC medical centers, INTELLECT, INTERVIEWING, MEDICAL protocols, NURSES, QUESTIONNAIRES, SEPSIS, OCCUPATIONAL roles
Abstract

The aim of the present survey was to evaluate nurses’ knowledge regarding sepsis in Greece. A total of 835 registered nurses (125 males/710 females) from tertiary hospitals in Greece were interviewed from April 2008 to December 2009. All participants completed a self-completed questionnaire about assessment of sepsis (see Figure 1). Basic demographic information was recorded. The protocol and questionnaire were approved by the Ethics Committees of participating hospitals. The majority of the participants answered correctly regarding awareness of systemic inflammation – 83.5% regarding the role of temperature in the definition of systemic inflammation; 81.3% regarding the importance of white blood cell count; and 49.9% and 46.3% regarding the role of tachycardia and tachypnoea, respectively. The same pattern was observed regarding the answers about the assessment of sepsis – 79.4% of the nurses answered correctly about the role of blood pressure; 70.9% about the role of urine volume; and 43.5% about the importance of oxygen saturation. Finally, 57.2% of the participants confirmed that in practice they followed the current guidelines for the diagnosis and treatment of patients with sepsis. The study has established baseline data with which future studies can be compared. [ABSTRACT FROM PUBLISHER]

Published
2014
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14. Clinical experience with indanyl carbenicillin in urinary tract infections

Author

Giamarellou E, Daikos G, Papazachos G, and Piperakis G

Subjects
Adult, Male, medicine.medical_specialty, Urinary system, Gastroenterology, Indanyl carbenicillin, Internal medicine, Humans, Medicine, Pseudomonas Infections, In patient, Pathogen, Escherichia coli Infections, Aged, biology, business.industry, Pseudomonas, General Medicine, Bacteriological Cure, Middle Aged, Carbenicillin, biology.organism_classification, Surgery, Proteus, Acute Disease, Chronic Disease, Urinary Tract Infections, Female, Proteus Infections, business, medicine.drug
Abstract

SummaryA trial was carried out in 30 patients to assess the effectiveness of indanyl carbenicillin in acute or chronic urinary tract infections, many of which were complicated by a pathological urological or medical condition. In all patients, infection was due to a single species of pathogen: E. coli (19), Proteus (6), and Pseudomonas (5). Oral doses of 1 g indanyl carbenicillin were given 6-hourlyfor an average of 10 days.Results showed a clinical and bacteriological cure in 13 {43.8 %)patients. In 6 patients, although there was initial clinical improvement, the pathogen developed resistance during therapy. In 7 patients, there was super-infection with another organism. Four patients were withdrawn early in treatment because of side-effects, mainly gastrointestinal in origin. Indanyl carbenicillin proved very effective in eradicating all strains of Proteus and Pseudomonas and 12 (70.6%) of the 17 strains of E. coli in patients completing the full course of treatment.

Published
1976
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16. Oral fosfomycin for the treatment of chronic bacterial prostatitis.

Author

Karaiskos I, Galani L, Sakka V, Gkoufa A, Sopilidis O, Chalikopoulos D, Alivizatos G, and Giamarellou E

Subjects
Administration, Oral, Adult, Aged, Anti-Bacterial Agents administration & dosage, Chronic Disease, Enterococcus faecalis drug effects, Escherichia coli drug effects, Fosfomycin administration & dosage, Humans, Klebsiella drug effects, Male, Microbial Sensitivity Tests, Middle Aged, Prospective Studies, Anti-Bacterial Agents therapeutic use, Drug Resistance, Multiple, Bacterial, Fosfomycin therapeutic use, Prostatitis drug therapy, Prostatitis microbiology
Abstract

Background: Chronic bacterial prostatitis (CBP) is a difficult-to-treat infection as only a few antibiotics achieve therapeutic concentrations in the prostate. Data on the efficacy and safety of oral fosfomycin for the treatment of CBP are limited., Objectives: To analyse the efficacy and safety of fosfomycin in CBP due to MDR pathogens., Methods: In a prospective observational study, an oral regimen of 3 g of fosfomycin q24h for 1 week followed by 3 g q48h for a treatment duration of 6-12 weeks was administered. The outcome was clinical and microbiological cure rate at the end of treatment (EOT) and rate of relapse at 3 and 6 months., Results: The study included 44 patients. The most common pathogen was Escherichia coli (66%), followed by Klebsiella spp. (14%) and Enterococcus faecalis (14%). Most strains were MDR (59%) and 23% had an ESBL phenotype; 33 of 44 strains were resistant to fluoroquinolones, but all were susceptible to fosfomycin (median MIC for Gram-negative pathogens 1.5 mg/L). In 25 patients, treatment was administered for 6 weeks, whereas in the remaining 19 patients it was prolonged to 12 weeks based on the presence of calcifications in the prostate. Cure rate was 82% at EOT and 80% and 73% at 3 and 6 months accordingly. Microbiological eradication was achieved in 86% and 77% at EOT and at 6 months, respectively. Failure was observed in 12 patients. The most common adverse event was diarrhoea (18%)., Conclusions: Oral fosfomycin, particularly in the era of MDR prevalence, represents an attractive, safe and effective alternative to fluoroquinolones for the treatment of CBP., (© The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.)

Published
2019
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17. Raising concerns about the Sepsis-3 definitions.

Author

Sartelli M, Kluger Y, Ansaloni L, Hardcastle TC, Rello J, Watkins RR, Bassetti M, Giamarellou E, Coccolini F, Abu-Zidan FM, Adesunkanmi AK, Augustin G, Baiocchi GL, Bala M, Baraket O, Beltran MA, Jusoh AC, Demetrashvili Z, De Simone B, de Souza HP, Cui Y, Davies RJ, Dhingra S, Diaz JJ, Di Saverio S, Dogjani A, Elmangory MM, Enani MA, Ferrada P, Fraga GP, Frattima S, Ghnnam W, Gomes CA, Kanj SS, Karamarkovic A, Kenig J, Khamis F, Khokha V, Koike K, Kok KYY, Isik A, Labricciosa FM, Latifi R, Lee JG, Litvin A, Machain GM, Manzano-Nunez R, Major P, Marwah S, McFarlane M, Memish ZA, Mesina C, Moore EE, Moore FA, Naidoo N, Negoi I, Ofori-Asenso R, Olaoye I, Ordoñez CA, Ouadii M, Paolillo C, Picetti E, Pintar T, Ponce-de-Leon A, Pupelis G, Reis T, Sakakushev B, Kafil HS, Sato N, Shah JN, Siribumrungwong B, Talving P, Tranà C, Ulrych J, Yuan KC, and Catena F

Subjects
Arterial Pressure, Consensus, Glasgow Coma Scale, Humans, Organ Dysfunction Scores, Sensitivity and Specificity, Sepsis mortality, Data Accuracy, Sepsis classification, Severity of Illness Index
Abstract

The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions., Competing Interests: Not applicable.Not applicable.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Published
2018
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18. Infective aortic valve endocarditis from Coxiella burnetii.

Author

Panou F, Papadopoulos C, Kolokathis F, Gannitsioti E, Tsiodras S, Giamarellou E, and Kremastinos DT

Subjects
Anti-Infective Agents therapeutic use, Aortic Valve Insufficiency drug therapy, Endocarditis, Bacterial drug therapy, Humans, Male, Middle Aged, Treatment Outcome, Aortic Valve Insufficiency diagnosis, Aortic Valve Insufficiency microbiology, Coxiella burnetii isolation & purification, Endocarditis, Bacterial diagnosis, Endocarditis, Bacterial microbiology, Q Fever complications
Abstract

We describe the case of a patient with a clinical picture of heart failure, which appeared and worsened rapidly following a reported febrile respiratory infection. The echocardiogram and serological tests established the diagnosis of aortic valve disease from Coxiella Burnetii.

Published
2007

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