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1. Personalized mechanical ventilation guided by ultrasound in patients with acute respiratory distress syndrome (PEGASUS): study protocol for an international randomized clinical trial

Author

Sinnige, Jante S., Smit, Marry R., Ghose, Aniruddha, de Grooth, Harm-Jan, Itenov, Theis Skovsgaard, Ischaki, Eleni, Laffey, John, Paulus, Frederique, Póvoa, Pedro, Pierrakos, Charalampos, Pisani, Luigi, Roca, Oriol, Schultz, Marcus J., Szuldrzynski, Konstanty, Tuinman, Pieter R., Zimatore, Claudio, and Bos, Lieuwe D. J.

Published
2024
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6. Field evaluation of the diagnostic performance of EasyScan GO: a digital malaria microscopy device based on machine-learning

Author

Das, Debashish, Vongpromek, Ranitha, Assawariyathipat, Thanawat, Srinamon, Ketsanee, Kennon, Kalynn, Stepniewska, Kasia, Ghose, Aniruddha, Sayeed, Abdullah Abu, Faiz, M. Abul, Netto, Rebeca Linhares Abreu, Siqueira, Andre, Yerbanga, Serge R., Ouédraogo, Jean Bosco, Callery, James J., Peto, Thomas J., Tripura, Rupam, Koukouikila-Koussounda, Felix, Ntoumi, Francine, Ong’echa, John Michael, Ogutu, Bernhards, Ghimire, Prakash, Marfurt, Jutta, Ley, Benedikt, Seck, Amadou, Ndiaye, Magatte, Moodley, Bhavani, Sun, Lisa Ming, Archasuksan, Laypaw, Proux, Stephane, Nsobya, Sam L., Rosenthal, Philip J., Horning, Matthew P., McGuire, Shawn K., Mehanian, Courosh, Burkot, Stephen, Delahunt, Charles B., Bachman, Christine, Price, Ric N., Dondorp, Arjen M., Chappuis, François, Guérin, Philippe J., and Dhorda, Mehul

Published
2022
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7. Personalized mechanical ventilation guided by ultrasound in patients with acute respiratory distress syndrome (PEGASUS):study protocol for an international randomized clinical trial

Author

Sinnige, Jante S., Smit, Marry R., Ghose, Aniruddha, de Grooth, Harm-Jan, Itenov, Theis Skovsgaard, Ischaki, Eleni, Laffey, John, Paulus, Frederique, Póvoa, Pedro, Pierrakos, Charalampos, Pisani, Luigi, Roca, Oriol, Schultz, Marcus J., Szuldrzynski, Konstanty, Tuinman, Pieter R., Zimatore, Claudio, Bos, Lieuwe D. J., Sinnige, Jante S., Smit, Marry R., Ghose, Aniruddha, de Grooth, Harm-Jan, Itenov, Theis Skovsgaard, Ischaki, Eleni, Laffey, John, Paulus, Frederique, Póvoa, Pedro, Pierrakos, Charalampos, Pisani, Luigi, Roca, Oriol, Schultz, Marcus J., Szuldrzynski, Konstanty, Tuinman, Pieter R., Zimatore, Claudio, and Bos, Lieuwe D. J.

Abstract

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a frequent cause of hypoxemic respiratory failure with a mortality rate of approximately 30%. Identifying ARDS subphenotypes based on "focal" or "non-focal" lung morphology has the potential to better target mechanical ventilation strategies of individual patients. However, classifying morphology through chest radiography or computed tomography is either inaccurate or impractical. Lung ultrasound (LUS) is a non-invasive bedside tool that can accurately distinguish "focal" from "non-focal" lung morphology. We hypothesize that LUS-guided personalized mechanical ventilation in ARDS patients leads to a reduction in 90-day mortality compared to conventional mechanical ventilation.METHODS: The Personalized Mechanical Ventilation Guided by UltraSound in Patients with Acute Respiratory Distress Syndrome (PEGASUS) study is an investigator-initiated, international, randomized clinical trial (RCT) that plans to enroll 538 invasively ventilated adult intensive care unit (ICU) patients with moderate to severe ARDS. Eligible patients will receive a LUS exam to classify lung morphology as "focal" or "non-focal". Thereafter, patients will be randomized within 12 h after ARDS diagnosis to receive standard care or personalized ventilation where the ventilation strategy is adjusted to the morphology subphenotype, i.e., higher positive end-expiratory pressure (PEEP) and recruitment maneuvers for "non-focal" ARDS and lower PEEP and prone positioning for "focal" ARDS. The primary endpoint is all-cause mortality at day 90. Secondary outcomes are mortality at day 28, ventilator-free days at day 28, ICU length of stay, ICU mortality, hospital length of stay, hospital mortality, and number of complications (ventilator-associated pneumonia, pneumothorax, and need for rescue therapy). After a pilot phase of 80 patients, the correct interpretation of LUS images and correct application of the intervention within the safe limits

Published
2024

8. Personalized mechanical ventilation guided by ultrasound in patients with acute respiratory distress syndrome (PEGASUS): study protocol for an international randomized clinical trial

Author

Sinnige, Jante J.S., Smit, Marry M.R., Ghose, Aniruddha, de Grooth, Harm Jan, Itenov, Theis Skovsgaard, Ischaki, Eleni, Laffey, John, Paulus, Frederique, Povoa, Pedro, Pierrakos, Charalampos, Pisani, Luigi, Roca, Oriol, Schultz, Marcus M.J., Szuldrzynski, Konstanty, Tuinman, Pieter Roel, Zimatore, Claudio, Bos, Lieuwe D J L.D., Sinnige, Jante J.S., Smit, Marry M.R., Ghose, Aniruddha, de Grooth, Harm Jan, Itenov, Theis Skovsgaard, Ischaki, Eleni, Laffey, John, Paulus, Frederique, Povoa, Pedro, Pierrakos, Charalampos, Pisani, Luigi, Roca, Oriol, Schultz, Marcus M.J., Szuldrzynski, Konstanty, Tuinman, Pieter Roel, Zimatore, Claudio, and Bos, Lieuwe D J L.D.

Abstract

Background :Acute respiratory distress syndrome (ARDS) is a frequent cause of hypoxemic respiratory failure with a mortality rate of approximately 30%. Identifying ARDS subphenotypes based on “focal” or “non-focal” lung morphology has the potential to better target mechanical ventilation strategies of individual patients. However, classifying morphology through chest radiography or computed tomography is either inaccurate or impractical. Lung ultrasound (LUS) is a non-invasive bedside tool that can accurately distinguish “focal” from “non-focal” lung morphology. We hypothesize that LUS-guided personalized mechanical ventilation in ARDS patients leads to a reduction in 90-day mortality compared to conventional mechanical ventilation. Methods: The Personalized Mechanical Ventilation Guided by UltraSound in Patients with Acute Respiratory Distress Syndrome (PEGASUS) study is an investigator-initiated, international, randomized clinical trial (RCT) that plans to enroll 538 invasively ventilated adult intensive care unit (ICU) patients with moderate to severe ARDS. Eligible patients will receive a LUS exam to classify lung morphology as “focal” or “non-focal”. Thereafter, patients will be randomized within 12 h after ARDS diagnosis to receive standard care or personalized ventilation where the ventilation strategy is adjusted to the morphology subphenotype, i.e. higher positive end-expiratory pressure (PEEP) and recruitment maneuvers for “non-focal” ARDS and lower PEEP and prone positioning for “focal” ARDS. The primary endpoint is all-cause mortality at day 90. Secondary outcomes are mortality at day 28, ventilator-free days at day 28, ICU length of stay, ICU mortality, hospital length of stay, hospital mortality, and number of complications (ventilator-associated pneumonia, pneumothorax, and need for rescue therapy). After a pilot phase of 80 patients, the correct interpretation of LUS images and correct application of the intervention within the safe limits of mechani, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2024

9. Personalized Mechanical Ventilation Guided by UltraSound in Patients with Acute Respiratory Distress Syndrome (PEGASUS): study protocol for an international randomized clinical trial.

Author

Sinnige, Jante, primary, Smit, Marry, additional, Ghose, Aniruddha, additional, de Grooth, Harm-Jan, additional, Itenov, Theis Skovsgaard, additional, Ischaki, Eleni, additional, Laffey, John, additional, Paulus, Frederique, additional, Póvoa, Pedro, additional, Pierrakos, Charalampos, additional, Pisani, Luigi, additional, Roca, Oriol, additional, Schultz, Marcus, additional, Szuldrzynski, Konstanty, additional, Tuinman, Pieter Roel, additional, Zimatore, Claudio, additional, and Bos, Lieuwe, additional

Published
2024
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10. Mystery Under the Hood: Ability of Spitting Among the Morphologically Indistinct Population of Naja Kaouthia (Squamata: Elapidae)

Author

Rahman, Md. Mizanur, primary, Noman, Mohammed, additional, Uddin, Md. Asir, additional, Al Haidar, Ibrahim Khalil, additional, Shaikh, Abdul Auawal, additional, Islam, Md. Rafiqul, additional, Rudra, Sajib, additional, Abu Sayeed, Abdullah, additional, Amin, Mohammad Robed, additional, Kuch, Ulrich, additional, Ghose, Aniruddha, additional, Ahsan, Md. Farid, additional, Faiz, Md. Abul, additional, and Chowdhury, Mohammad Abdul Wahed, additional

Published
2024
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11. An evaluation of purified Salmonella Typhi protein antigens for the serological diagnosis of acute typhoid fever.

Author

Tran Vu Thieu, Nga, Trinh Van, Tan, Tran Tuan, Anh, Klemm, Elizabeth, Nguyen Ngoc Minh, Chau, Voong Vinh, Phat, Pham Thanh, Duy, Ho Ngoc Dan, Thanh, Pham Duc, Trung, Langat, Pinky, Martin, Laura, Galan, Jorge, Liang, Li, Felgner, Philip, Davies, D, de Jong, Hanna, Maude, Rapeephan, Fukushima, Masako, Wijedoru, Lalith, Ghose, Aniruddha, Samad, Rasheda, Dondorp, Arjen, Faiz, Abul, Darton, Thomas, Pollard, Andrew, Thwaites, Guy, Dougan, Gordon, Parry, Christopher, and Baker, Stephen

Subjects
Bangladesh, Diagnostics, Enteric fever, Febrile disease, IgM, Salmonella Typhi, Typhoid fever, Vi polysaccharide, Antibodies, Bacterial, Antigens, Bacterial, Bacteriological Techniques, Bangladesh, Humans, Immunoglobulin M, Polysaccharides, Bacterial, Salmonella typhi, Typhoid Fever
Abstract

OBJECTIVES: The diagnosis of typhoid fever is a challenge. Aiming to develop a typhoid diagnostic we measured antibody responses against Salmonella Typhi (S. Typhi) protein antigens and the Vi polysaccharide in a cohort of Bangladeshi febrile patients. METHODS: IgM against 12 purified antigens and the Vi polysaccharide was measured by ELISA in plasma from patients with confirmed typhoid fever (n = 32), other confirmed infections (n = 17), and healthy controls (n = 40). ELISAs with the most specific antigens were performed on plasma from 243 patients with undiagnosed febrile disease. RESULTS: IgM against the S. Typhi protein antigens correlated with each other (rho > 0.8), but not against Vi (rho 0.85, respectively. Applying a dynamic cut-off to patients with undiagnosed febrile disease suggested that 34-58% had an IgM response indicative of typhoid. CONCLUSIONS: We evaluated the diagnostic potential of several S. Typhi antigens; our assays give good sensitivity and specificity, but require further assessment in differing patient populations.

Published
2017

12. Combining species distribution models and big datasets may provide finer assessments of snakebite impacts.

Author

Chowdhury, Mohammad Abdul Wahed, Müller, Johannes, Ghose, Aniruddha, Amin, Robed, Sayeed, Abdullah Abu, Kuch, Ulrich, and Faiz, Mohammad Abul

Subjects
SNAKEBITES, SPECIES distribution, MEDICAL climatology, POPULATION density, NEGLECTED diseases, CLIMATE change
Abstract

Background: Snakebite is a major poverty-related neglected tropical disease. An integrated scientific approach is needed to understand the dynamics of this important health issue. Our objective was to estimate snakebite occurrence in a tropical area by using a blend of ecological modelling and robust statistical analysis. Methods: The present study used climatic, environmental, and human population density data to determine the area with snakebite occurrence-probability for the first time in Bangladesh. We also analysed a large, 16-year dataset of hospitalized snakebite cases to reveal the epidemiology of snakebite in the south-eastern zone of the country. Findings: Our results show that cobra bite is the most commonly occurring venomous snakebite in humans (around ~12% of the total yearly snakebite records), and men are more frequently bitten than women (2/3 of human victims are men). Most bites occur during the rainy season for cobra and green pit viper, while krait bites are not restricted to any particular season. As snakebite incidents are closely related to climate conditions, we can model snakebite risk using temperature and precipitation variables. Whereas there is a lack of snakebite reports from several parts of the study area in official records, our models predict that the entire study area is favourable for snakebite incidents. Based on the combined evidence we estimate that about 200,000 snakebite events occur every year in the south-eastern part of Bangladesh alone. Considering future global climate change, our model projections show that snakebite incidence in Bangladesh might not significantly decrease in the future (- 2070-); however, the distribution of probabilities might change, with a predicted increase of snakebite incidence in the hilly areas of the country. Conclusions: Using climatic data to predict snakebite incidence in Bangladesh allowed us to provide estimations of the total annual number of snakebite cases in the study area. As in most countries, the scarcity of accurate epidemiological data in official records might have masked the real magnitude of this problem. Our analysis suggests that the problem of snakebite envenoming in Bangladesh might be worse than currently perceived. A long-term sustainable snakebite program plan should be designed and institutionalized, considering climatic, geographical and human demographic variables, to obtain better data and facilitate the implementation of accurate snakebite management programs for this country. Author summary: Snakebite envenoming is an important health problem in Bangladesh. A community-based survey conducted in 2009 indicated that around 700,000 snakebites/year may occur in this country. However, until now, there is no study estimating the incidence of snakebite in Bangladesh from the aspect of ecology. Considering the climatic, environmental, and human population variables, a large, 16-year clinico-epidemiological dataset of snakebite patients was analysed to portray snakebite occurrence probability in Chattogram Division, which comprises the south-eastern part of Bangladesh. Five species distribution models were used to map snakebite-prone areas. We found that the study area has large differences in the predicted incidence of snakebite. Our predictions indicate that around 200,000 snakebite cases per year might occur in the study area, where the latest estimate on 2009 estimated less than half that number for this division. Further, predictions for the year 2070 provide us with similar numbers, independent of the global increase in temperature. As snakebite will remain a major health problem for this country in the next 50 years, we propose the development of a sustainable management plan aiming to limit human-snake conflicts and their consequences while safeguarding also snakes and the ecosystem services they provide especially to agriculture. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Effectiveness of calcium channel blockade for organophosphorus and carbamate pesticide poisoning – study protocol for an open label, pragmatic, 3-arm RCT repurposing two widely available medicines

Author

Rabbi Chowdhury, Fazle, primary, Shaw, Suvodip, additional, Abu Sayeed, Abdullah, additional, Roy, Soumitra, additional, Rahman, Abu Shahin Mohammad Mahbubur, additional, Zafrin, Nahida, additional, Tarafder, Pritish, additional, Rashid, Muhammad Halimur, additional, Ghose, Aniruddha, additional, Chakraborty, Shishir Ranjan, additional, Rahman, Muhammad Khalilur, additional, Rahman, Muhammad Sayedur, additional, Parker, Richard, additional, Ullah, Muhammad Mahib, additional, Hassan, Zakir, additional, Sohag, Abdullah Al Mamun, additional, Amin, Muhammad Robed, additional, Bari, Muhammad Shafiqul, additional, Norrie, John, additional, Faiz, M. A., additional, and Eddleston, Michael, additional

Published
2023
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14. Acetaminophen as a Renoprotective Adjunctive Treatment in Patients With Severe and Moderately Severe Falciparum Malaria : A Randomized, Controlled, Open-Label Trial

Author

Plewes, Katherine, Kingston, Hugh W. F., Ghose, Aniruddha, Wattanakul, Thanaporn, Hassan, Md. Mahtab Uddin, Haider, Md. Shafiul, Dutta, Prodip K., Islam, Md. Akhterul, Alam, Shamsul, Jahangir, Selim Md., Zahed, A. S. M., Sattar, Md. Abdus, Chowdhury, M. A. Hassan, Herdman, M. Trent, Leopold, Stije J., Ishioka, Haruhiko, Piera, Kim A., Charunwatthana, Prakaykaew, Silamut, Kamolrat, Yeo, Tsin W., Lee, Sue J., Mukaka, Mavuto, Maude, Richard J., Turner, Gareth D. H., Faiz, Md. Abul, Tarning, Joel, Oates, John A., Anstey, Nicholas M., White, Nicholas J., Day, Nicholas P. J., Hossain, Md. Amir, Roberts, L. Jackson, and Dondorp, Arjen M.

Published
2018

15. Asian Snakes

Author

Ghose, Aniruddha, White, Julian, Brent, Jeffrey, editor, Burkhart, Keith, editor, Dargan, Paul, editor, Hatten, Benjamin, editor, Megarbane, Bruno, editor, Palmer, Robert, editor, and White, Julian, editor

Published
2017
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16. Lessons from the field: compound-specific management in acute pesticide poisoning.

Author

Verma, Vasundhara R, Lamb, Thomas, Sattar, Md Abdus, Ghose, Aniruddha, and Eddleston, Michael

Subjects
POISONING, PESTICIDES, MEDICAL emergencies, LENGTH of stay in hospitals, HOSPITAL costs, ABORTIFACIENTS
Abstract

Pesticide poisoning is a common medical emergency in the rural tropics, with significant associated mortality. Pesticide poisoning is an umbrella term that encompasses a wide variety of substances with differing clinical toxidromes and outcomes. Despite this, confirmation of the specific compound ingested is rarely performed. In this Lessons from the Field, we argue that pesticide-specific management is integral to optimise management. Using data from a quality improvement project in Chittagong, Bangladesh, we demonstrate that identifying the specific compound is possible in most patients through careful history taking and examination of the pesticide bottle. Identification of the specific compound is essential for anticipating and reducing complications, administering appropriate and timely management and reducing the length of hospital stay and cost of unnecessary medical intervention. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Non-COVID-19 intensive care admissions during the pandemic: a multinational registry-based study

Author

McLarty, Joshua, primary, Litton, Edward, additional, Beane, Abigail, additional, Aryal, Diptesh, additional, Bailey, Michael, additional, Bendel, Stepani, additional, Burghi, Gaston, additional, Christensen, Steffen, additional, Christiansen, Christian Fynbo, additional, Dongelmans, Dave A, additional, Fernandez, Ariel L, additional, Ghose, Aniruddha, additional, Hall, Ros, additional, Haniffa, Rashan, additional, Hashmi, Madiha, additional, Hashimoto, Satoru, additional, Ichihara, Nao, additional, Kumar Tirupakuzhi Vijayaraghavan, Bharath, additional, Lone, Nazir I, additional, Arias López, Maria del Pilar, additional, Mat Nor, Mohamed Basri, additional, Okamoto, Hiroshi, additional, Priyadarshani, Dilanthi, additional, Reinikainen, Matti, additional, Soares, Marcio, additional, Pilcher, David, additional, and Salluh, Jorge, additional

Published
2023
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19. Predictors of Duration and Demand of Oxygen Therapy in Hospitalized RT-PCR Positive COVID-19 Patients

Author

Kahnom, Mehrunnissa, primary, Uddin, Rabiul Alam Md Erfan, additional, Ghose, Aniruddha, additional, Zahed, A S M, additional, Islam, Mohammad Kamrul, additional, Karim, Razaul, additional, Karim, A T M Rezaul, additional, Ara, Shamim, additional, Ahmad, Rizwan, additional, Chowdhury, Md Akhtarul Islam, additional, and Hossain, Md Amir, additional

Published
2023
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20. Non-COVID-19 intensive care admissions during the pandemic: a multinational registry-based study

Author

McLarty, Joshua, Litton, Edward, Beane, Abigail, Aryal, Diptesh, Bailey, Michael, Bendel, Stepani, Burghi, Gaston, Christensen, Steffen, Christiansen, Christian Fynbo, Dongelmans, Dave A, Fernandez, Ariel L, Ghose, Aniruddha, Hall, Ros, Haniffa, Rashan, Hashmi, Madiha, Hashimoto, Satoru, Ichihara, Nao, Kumar Tirupakuzhi Vijayaraghavan, Bharath, Lone, Nazir I, Arias López, Maria del Pilar, Mat Nor, Mohamed Basri, Okamoto, Hiroshi, Priyadarshani, Dilanthi, Reinikainen, Matti, Soares, Marcio, Pilcher, David, and Salluh, Jorge

Abstract

BackgroundThe COVID-19 pandemic resulted in a large number of critical care admissions. While national reports have described the outcomes of patients with COVID-19, there is limited international data of the pandemic impact on non-COVID-19 patients requiring intensive care treatment.MethodsWe conducted an international, retrospective cohort study using 2019 and 2020 data from 11 national clinical quality registries covering 15 countries. Non-COVID-19 admissions in 2020 were compared with all admissions in 2019, prepandemic. The primary outcome was intensive care unit (ICU) mortality. Secondary outcomes included in-hospital mortality and standardised mortality ratio (SMR). Analyses were stratified by the country income level(s) of each registry.FindingsAmong 1 642 632 non-COVID-19 admissions, there was an increase in ICU mortality between 2019 (9.3%) and 2020 (10.4%), OR=1.15 (95% CI 1.14 to 1.17, p<0.001). Increased mortality was observed in middle-income countries (OR 1.25 95% CI 1.23 to 1.26), while mortality decreased in high-income countries (OR=0.96 95% CI 0.94 to 0.98). Hospital mortality and SMR trends for each registry were consistent with the observed ICU mortality findings. The burden of COVID-19 was highly variable, with COVID-19 ICU patient-days per bed ranging from 0.4 to 81.6 between registries. This alone did not explain the observed non-COVID-19 mortality changes.InterpretationIncreased ICU mortality occurred among non-COVID-19 patients during the pandemic, driven by increased mortality in middle-income countries, while mortality decreased in high-income countries. The causes for this inequity are likely multi-factorial, but healthcare spending, policy pandemic responses, and ICU strain may play significant roles.

Published
2024
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21. Mapping the travel patterns of people with malaria in Bangladesh

Author

Sinha, Ipsita, Sayeed, Abdullah Abu, Uddin, Didar, Wesolowski, Amy, Zaman, Sazid Ibna, Faiz, M. Abul, Ghose, Aniruddha, Rahman, M. Ridwanur, Islam, Akramul, Karim, Mohammad Jahirul, Saha, Anjan, Rezwan, M. Kamar, Shamsuzzaman, Abul Khair Mohammad, Jhora, Sanya Tahmina, Aktaruzzaman, M. M., Chang, Hsiao-Han, Miotto, Olivo, Kwiatkowski, Dominic, Dondorp, Arjen M., Day, Nicholas P. J., Hossain, M. Amir, Buckee, Caroline, and Maude, Richard J.

Published
2020
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22. Snake Envenomation in Bangladesh

Author

Ghose, Aniruddha, Faiz, Abul, Gopalakrishnakone, P., Editor-in-chief, Faiz, Abul, editor, Fernando, Ravindra, editor, Gnanathasan, Christeine Ariaranee, editor, Habib, Abdulrazaq Garba, editor, and Yang, Chen-Chang, editor

Published
2015
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23. Suitability of Low and Middle Income Country Data Derived Prognostics Models for Benchmarking Mortality in a Multinational Asia Critical Care Registry Network

Author

Gamage Dona, Dilanthi, primary, Aryal, Diptesh, additional, Ghose, Aniruddha, additional, Hashmi, Madiha, additional, Nath, Ranjan Kumar, additional, Mat-Nor, Mohd Basri, additional, Thwaites, Louise, additional, Tripathy, Swagata, additional, Kumar Tirupakuzhi Vijavaraghavan, Bharath, additional, Yen, Lam Minh, additional, Dondorp, Arjen M., additional, Haniffa, Rashan, additional, Nirantharakumar, Krishnarajah, additional, Parekh, Dhruv, additional, and Beane, Abigail, additional

Published
2023
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25. Supplementary materials for 'Mixed methods study protocol for combining stakeholder-led rapid evaluation with near real-time continuous registry data to facilitate evaluations of quality of care in intensive care units'

Author

Rashan, Aasiyah, Beane, Abi, Ghose, Aniruddha, Dondorp, Arjen M, Kwizera, Arthur, Vijayaraghavan, Bharath Kumar Tirupakuzhi, Biccard, Bruce, Righy, Cassia, Thwaites, Louise, Pell, Christopher, Sendagire, Cornelius, Thomson, David, Aryal, Diptesh, Wagstaff, Duncan, Nadia, Farah, Putoto, Giovanni, Paneru, Hem Raj, Udayanga, Ishara, Amuasi, John, Salluh, Jorge, Gokhale, Krishna, Nirantharakumar, Krishnarajah, Pisani, Luigi, Hashmi, Madiha, Schultz, Marcus, Ghalib, Maryam Shamal, Mukaka, Mavuto, Mat-Nor, Mohammed Basri, Siaw-frimpong, Moses, Surenthirakumaran, Rajendra, haniffa, rashan, Kaddu, Ronnie P, Pinto Pereira, Snehal, Murthy, Srinivas, Harris, Steve, Moonesinghe, Suneetha Ramani, Vengadasalam, Sutharshan, Tripathy, Swagata, Gooden, Tiffany, Tolppa, Timo, Pari, Vrindha, Waweru-Siika, Wangari, and Minh, Yen Lam

Abstract

Supplemental materials for article titled 'Mixed methods study protocol for combining stakeholder-led rapid evaluation with near real-time continuous registry data to facilitate evaluations of quality of care in intensive care units'

Published
2023
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28. Implementation of Ecological Distribution of Venomous Snakes for Clinical Management of Snakebite in Bangladesh.

Author

Al Haidar, Ibrahim Khalil, Ghose, Aniruddha, Noman, Mohammed, Rahman, Md. Mizanur, Rudra, Sajib, Auawal, Abdul, Islam, Md. Rafiqul, Uddin, Md. Asir, Uddin, Rabiul Alam Md. Erfan, Sayeed, Abdullah Abu, Amin, Md. Robed, Ahsan, Md. Farid, Faiz, Md. Abul, and Chowdhury, Mohammad Abdul Wahed

Subjects
*SNAKEBITES, *POISONOUS snakes, *COBRAS, *VENOM, *MEDICAL records, WESTERN countries
Abstract

Background: Snakebite envenoming is a global health problem, mostly in tropical and subtropical countries. Bangladesh is a subtropical country facing thousands of snakebite envenoming death every year. Knowledge of the distribution of venomous snakes is necessary to identify snakebite-prone areas, develop strategies for prevention and management, and reduce venom-induced mortalities and morbidities. Methods: An integrated effort of direct observations of snakes, qualitative analysis of museum specimen records, clinical records of snakebites, and scholarly literature records were used to understand the pattern of distribution of venomous snakes in Bangladesh. Results: We enlist 65 venomous snake species from Bangladesh and present detailed documentation on their distribution pattern. However, only nine species were considered medically relevant species because of their venom potentiality to kill humans and available clinical records of envenomation. The distribution pattern of those species divides the country into two major portions. A portion consists of northern, northwestern, and western parts of the country, which are habitats of Naja naja, Bungarus caeruleus, and B. lividus. Another portion comprised of the northeastern, southeastern, and southern parts of the country provides habitats for N. kaouthia, B. niger, and Trimeresurus erythrurus. However, Daboia. russelii had a different distribution pattern along the bank of the Padma and Meghna, and some coastal districts. Moreover, B. walli had a scattered distribution over the country. The knowledge of this ecological distribution of venomous snakes across the country bears a significant practical effect on clinical management of snakebite. Treating physicians can have a better understanding of possible offending snake species using this knowledge and the clinical syndromes produced by venoms. Conclusion: Pattern of distribution of medically relevant venomous snakes in Bangladesh approaches to initiate concise and specific bite management strategies for two distinct distributional regions of the country. Moreover, the distribution of D. russelii and B. walli demands specific strategies for bite management. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Increased intra- and extracellular granzyme expression in patients with tuberculosis

Author

Garcia-Laorden, M. Isabel, Blok, Dana C., Kager, Liesbeth M., Hoogendijk, Arie J., van Mierlo, Gerard J., Lede, Ivar O., Rahman, Wahid, Afroz, Rumana, Ghose, Aniruddha, Visser, Caroline E., Md Zahed, Abu Shahed, Husain, Md Anwar, Alam, Khan Mashrequl, Chandra Barua, Pravat, Hassan, Mahtabuddin, Hossain, Ahmed, Tayab, Md Abu, Day, Nick, Dondorp, Arjen M., de Vos, Alex F., and van der Poll, Tom

Published
2015
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31. Position statement on use of antivenom

Author

Amin, Md Robed, primary, Sayeed, Abdullah Abu, additional, Alam, Rabiul, additional, Ghose, Aniruddha, additional, Shahjahan, Mohammed, additional, Mahbubur Rahman, Abu Shahin Mohammed, additional, Mondal, Ratindra Nath, additional, and Faiz, Mohammad Abul, additional

Published
2022
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32. Randomized Controlled Trial of Levamisole Hydrochloride as Adjunctive Therapy in Severe Falciparum Malaria With High Parasitemia

Author

Maude, Richard J., Silamut, Kamolrat, Plewes, Katherine, Charunwatthana, Prakaykaew, Ho, May, Faiz, M. Abul, Rahman, Ridwanur, Hossain, Md Amir, Hassan, Mahtab U., Yunus, Emran Bin, Hoque, Gofranul, Islam, Faridul, Ghose, Aniruddha, Hanson, Josh, Schlatter, Joel, Lacey, Rachel, Eastaugh, Alison, Taming, Joel, Lee, Sue J., White, Nicholas J., Chotivanich, Kesinee, Day, Nicholas P. J., and Dondorp, Arjen M.

Published
2014

34. Acidosis and acute kidney injury in severe malaria

Author

Sriboonvorakul, Natthida, Ghose, Aniruddha, Hassan, M. Mahtab Uddin, Hossain, Md. Amir, Faiz, M. Abul, Pukrittayakamee, Sasithon, Chotivanich, Kesinee, Sukthana, Yaowalark, Leopold, Stije J., Plewes, Katherine, Day, Nicholas P. J., White, Nicholas J., Tarning, Joel, and Dondorp, Arjen M.

Published
2018
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35. Additional file 2 of Field evaluation of the diagnostic performance of EasyScan GO: a digital malaria microscopy device based on machine-learning

Author

Das, Debashish, Vongpromek, Ranitha, Assawariyathipat, Thanawat, Srinamon, Ketsanee, Kennon, Kalynn, Stepniewska, Kasia, Ghose, Aniruddha, Sayeed, Abdullah Abu, Faiz, M. Abul, Netto, Rebeca Linhares Abreu, Siqueira, Andre, Yerbanga, Serge R., Ouédraogo, Jean Bosco, Callery, James J., Peto, Thomas J., Tripura, Rupam, Koukouikila-Koussounda, Felix, Ntoumi, Francine, Ong’echa, John Michael, Ogutu, Bernhards, Ghimire, Prakash, Marfurt, Jutta, Ley, Benedikt, Seck, Amadou, Ndiaye, Magatte, Moodley, Bhavani, Sun, Lisa Ming, Archasuksan, Laypaw, Proux, Stephane, Nsobya, Sam L., Rosenthal, Philip J., Horning, Matthew P., McGuire, Shawn K., Mehanian, Courosh, Burkot, Stephen, Delahunt, Charles B., Bachman, Christine, Price, Ric N., Dondorp, Arjen M., Chappuis, François, Guérin, Philippe J., and Dhorda, Mehul

Abstract

Additional file 2. Parasite Density Estimation.

Published
2022
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36. Additional file 3 of Field evaluation of the diagnostic performance of EasyScan GO: a digital malaria microscopy device based on machine-learning

Author

Das, Debashish, Vongpromek, Ranitha, Assawariyathipat, Thanawat, Srinamon, Ketsanee, Kennon, Kalynn, Stepniewska, Kasia, Ghose, Aniruddha, Sayeed, Abdullah Abu, Faiz, M. Abul, Netto, Rebeca Linhares Abreu, Siqueira, Andre, Yerbanga, Serge R., Ouédraogo, Jean Bosco, Callery, James J., Peto, Thomas J., Tripura, Rupam, Koukouikila-Koussounda, Felix, Ntoumi, Francine, Ong’echa, John Michael, Ogutu, Bernhards, Ghimire, Prakash, Marfurt, Jutta, Ley, Benedikt, Seck, Amadou, Ndiaye, Magatte, Moodley, Bhavani, Sun, Lisa Ming, Archasuksan, Laypaw, Proux, Stephane, Nsobya, Sam L., Rosenthal, Philip J., Horning, Matthew P., McGuire, Shawn K., Mehanian, Courosh, Burkot, Stephen, Delahunt, Charles B., Bachman, Christine, Price, Ric N., Dondorp, Arjen M., Chappuis, François, Guérin, Philippe J., and Dhorda, Mehul

Abstract

Additional file 3. EasyScan Go.

Published
2022
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37. Additional file 1 of Field evaluation of the diagnostic performance of EasyScan GO: a digital malaria microscopy device based on machine-learning

Author

Das, Debashish, Vongpromek, Ranitha, Assawariyathipat, Thanawat, Srinamon, Ketsanee, Kennon, Kalynn, Stepniewska, Kasia, Ghose, Aniruddha, Sayeed, Abdullah Abu, Faiz, M. Abul, Netto, Rebeca Linhares Abreu, Siqueira, Andre, Yerbanga, Serge R., Ouédraogo, Jean Bosco, Callery, James J., Peto, Thomas J., Tripura, Rupam, Koukouikila-Koussounda, Felix, Ntoumi, Francine, Ong’echa, John Michael, Ogutu, Bernhards, Ghimire, Prakash, Marfurt, Jutta, Ley, Benedikt, Seck, Amadou, Ndiaye, Magatte, Moodley, Bhavani, Sun, Lisa Ming, Archasuksan, Laypaw, Proux, Stephane, Nsobya, Sam L., Rosenthal, Philip J., Horning, Matthew P., McGuire, Shawn K., Mehanian, Courosh, Burkot, Stephen, Delahunt, Charles B., Bachman, Christine, Price, Ric N., Dondorp, Arjen M., Chappuis, François, Guérin, Philippe J., and Dhorda, Mehul

Abstract

Additional file 1. STARD-2015-Checklist.

Published
2022
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43. Performance evaluation of a multinational data platform for critical care in Asia

Author

Pisani, Luigi, primary, Rashan, Thalha, additional, Shamal, Maryam, additional, Ghose, Aniruddha, additional, Vijayaraghavan, Bharath Kumar Tirupakuzhi, additional, Tripathy, Swagata, additional, Aryal, Diptesh, additional, Hashmi, Madiha, additional, Nor, Basri, additional, Minh, Yen Lam, additional, Dondorp, Arjen M., additional, Haniffa, Rashan, additional, and Beane, Abi, additional

Published
2021
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45. Erratum to: the role of previously unmeasured organic acids in the pathogenesis of severe malaria

Author

Herdman, M. Trent, Sriboonvorakul, Natthida, Leopold, Stije J., Douthwaite, Sam, Mohanty, Sanjib, Hassan, M. Mahtab Uddin, Maude, Richard J., Kingston, Hugh W. F., Plewes, Katherine, Charunwatthana, Prakaykaew, Silamut, Kamolrat, Woodrow, Charles J., Ghose, Aniruddha, Chotinavich, Kesinee, Hossain, Md Amir, Faiz, M. Abul, Mishra, Saroj, Leepipatpiboon, Natchanun, White, Nicholas J., Day, Nicholas P. J., Tarning, Joel, and Dondorp, Arjen M.

Published
2015
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47. Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

Author

Ashley, Elizabeth A., Dhorda, Mehul, Fairhurst, Rick M., Amaratunga, Chanaki, Lim, Parath, Suon, Seila, Sreng, Sokunthea, Anderson, Jennifer M., Mao, Sivanna, Sam, Baramey, Sopha, Chantha, Chuor, Char Meng, Nguon, Chea, Sovannaroth, Siv, Pukrittayakamee, Sasithon, Jittamala, Podjanee, Chotivanich, Kesinee, Chutasmit, Kitipumi, Suchatsoonthorn, Chaiyaporn, Runcharoen, Ratchadaporn, Hien, Tran Tinh, Thuy-Nhien, Nguyen Thanh, Thanh, Ngo Viet, Phu, Nguyen Hoan, Htut, Ye, Han, Kay-Thwe, Aye, Kyin Hla, Mokuolu, Olugbenga A., Olaosebikan, Rasaq R., Folaranmi, Olaleke O., Mayxay, Mayfong, Khanthavong, Maniphone, Hongvanthong, Bouasy, Newton, Paul N., Onyamboko, Marie A., Fanello, Caterina I., Tshefu, Antoinette K., Mishra, Neelima, Valecha, Neena, Phyo, Aung Pyae, Nosten, Francois, Yi, Poravuth, Tripura, Rupam, Borrmann, Steffen, Bashraheil, Mahfudh, Peshu, Judy, Faiz, M. Abul, Ghose, Aniruddha, Hossain, M. Amir, Samad, Rasheda, Rahman, M. Ridwanur, Hasan, M. Mahtabuddin, Islam, Akhterul, Miotto, Olivo, Amato, Roberto, MacInnis, Bronwyn, Stalker, Jim, Kwiatkowski, Dominic P., Bozdech, Zbynek, Jeeyapant, Atthanee, Cheah, Phaik Yeong, Sakulthaew, Tharisara, Chalk, Jeremy, Intharabut, Benjamas, Silamut, Kamolrat, Lee, Sue J., Vihokhern, Benchawan, Kunasol, Chanon, Imwong, Mallika, Tarning, Joel, Taylor, Walter J., Yeung, Shunmay, Woodrow, Charles J., Flegg, Jennifer A., Das, Debashish, Smith, Jeffery, Venkatesan, Meera, Plowe, Christopher V., Stepniewska, Kasia, Guerin, Philippe J., Dondorp, Arjen M., Day, Nicholas P., and White, Nicholas J.

Published
2014
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48. Altered Patterns of Compositional and Functional Disruption of the Gut Microbiota in Typhoid Fever and Nontyphoidal Febrile Illness

Author

Haak, Bastiaan W, primary, de Jong, Hanna K, additional, Kostidis, Sarantos, additional, Giera, Martin, additional, Maude, Rapeephan R, additional, Samad, Rasheda, additional, Wijedoru, Lalith, additional, Ghose, Aniruddha, additional, Faiz, Mohammed Abul, additional, Parry, Christopher M, additional, and Wiersinga, W Joost, additional

Published
2020
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