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13. The Scope of Biopolymers in Food Industry

Author

Gupta, Shreya, Ghosal, Anujit, Goswami, Ayanava, Bhawana, Nadda, Ashok Kumar, Sharma, Swati, Kalia, Susheel, Series Editor, Haraguchi, Kazutoshi, Editorial Board Member, Celli, Annamaria, Editorial Board Member, Ruiz-Hitzky, Eduardo, Editorial Board Member, Bismarck, Alexander, Editorial Board Member, Thomas, Sabu, Editorial Board Member, Kessler, Michael R., Editorial Board Member, Kaith, Balbir Singh, Editorial Board Member, Averous, Luc, Editorial Board Member, Gupta, Bhuvanesh, Editorial Board Member, Njuguna, James, Editorial Board Member, Boufi, Sami, Editorial Board Member, Sabaa, Magdy W., Editorial Board Member, Kumar Mishra, Ajay, Editorial Board Member, Pielichowski, Krzysztof, Editorial Board Member, Habibi, Youssef, Editorial Board Member, Focarete, Maria Letizia, Editorial Board Member, Jawaid, Mohammad, Editorial Board Member, Nadda, Ashok Kumar, editor, Sharma, Swati, editor, and Bhat, Rajeev, editor

Published
2022
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19. Linseed oil derived terpolymer/silica nanocomposite materials for anticorrosive coatings

Author

Alam, Manawwer, Alandis, Naser M., Zafar, Fahmina, Ghosal, Anujit, and Ahmed, Mukhtar

Subjects
Linseed-oil -- Usage, Corrosion and anti-corrosives -- Prevention, Coatings -- Composition -- Chemical properties, Engineering and manufacturing industries, Science and technology
Abstract

Formulation of sustainable resource-based organic-inorganic hybrid protective coatings have been achieved using Linseed oil-based silica hybrid with terpolymer (TP) as basic skeletal matrix. The fabrication of TP system was performed by using systematic one pot multi-facile steps (diol fatty amide-linseed oil-based polyester amide TP) synthesis route. The conversion of ester amide functional ends of TP to urethane was initiated to enhance adhesiveness, impermeability, and corrosion resistivity of the processed hybrid material. FT-IR and NMR ([sup.1]H, [sup.13]C, and [sup.29]Si) studies help in verifying the chemical structure and progress of the reaction. The formulation of smooth corrosion resistive coating was further analyzed by transmission electron microscopy, scanning electron microscope, and electrochemical corrosion studies. The in-situ tethering and homogeneous dispersion of inorganic moiety in nanoregime throughout the TP system further enhances the stability, wettability, and corrosion protection ability of the nanohybrid vegetable oil-based coating under corrosive environment. High phase angle value at higher frequency end indicates the stability of the coating system. Such coating systems composed of sustainable resource with improved mechanical, thermal, and corrosion protective properties have great potential in future applications. KEYWORDS corrosion, nanocomposite, renewable, seed oil, terpolymer, 1 | INTRODUCTION The ever-rising pollution and corrosive environment around have been enforcing the need to use greener alternatives such as vegetable oil (VO)-derived products. [1,2] The engineered VO products [...]

Published
2021
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20. Contributors

Author

Agarwal, Tarun, primary, Amirrah, Ibrahim N., additional, Anandharamakrishnan, C., additional, Ansari, Aafreen, additional, Arooj, Mahreen, additional, Bandara, Nandika, additional, Banjara, Nabaraj, additional, Barui, Ananya, additional, Basilio Heredia, J., additional, Bhunia, Kanishka, additional, Bose, Samprit, additional, Chawdhary, Rashmi, additional, Chetri, Rahul, additional, Dasgupta, Nandita, additional, Dasgupta, Shalini, additional, Datta, Pallab, additional, Dharmalingam, Sangeetha, additional, Dwari, Dipanjan, additional, Erkinbaev, Chyngyz, additional, Fauzi, Mh Busra, additional, Garcia-Carrasco, Melissa, additional, Ghosal, Anujit, additional, Gorhe, Nikhil, additional, Gutiérrez-Grijalva, Erick P., additional, Hada, Vaishnavi, additional, Hadem, Hushnaara, additional, Hameed, Mehavesh, additional, Hashmi, S.A.R., additional, Hettiarachchy, Navam, additional, Holliday, Darryl L., additional, Hulle, Nishant Rachayya Swami, additional, Jagajjanani Rao, K., additional, Jaiswal, Lily, additional, Jian, Law Xia, additional, Kamaruzaman, Nurkhuzaiah, additional, Khan, Manal, additional, Korumilli, Tarangini, additional, Kugarajah, Vaidhegi, additional, Law, Jia Xian, additional, Licea-Claverie, Angel, additional, Limayem, Alya, additional, Lokanathan, Yogeswaran, additional, Mahalakshmi, L., additional, Maiti, Tapas Kumar, additional, Maity, Sourav, additional, Mazlan, Zawani, additional, Mili, Medha, additional, Mishra, Bhartendu Nath, additional, Mohamed, Ahmed A., additional, Moses, J.A., additional, Mukherjee, Soma, additional, Naik, Ajay, additional, Nath, Debarshi, additional, Ng, Min Hwei, additional, Nie, Lei, additional, Nongmaithem, Sophia Devi, additional, Nor, Fatimah Mohd, additional, Ojha, Atul Kumar, additional, Pal, Abhinandan, additional, Pal, Kunal, additional, Panicker, Seema, additional, Parra-Aguilar, Itzel F., additional, Prashant, N., additional, Rad, Niloofar Khoshdel, additional, Ram, Mukesh Kumar, additional, Ramachandran, Rani Puthukulangara, additional, Ranjan, Shivendu, additional, Roy, Akash, additional, Sagiri, Sai Sateesh, additional, Saha, Sayandeep, additional, Salleh, Atiqah, additional, Sallehuddin, Nusaibah, additional, Santhosh, R., additional, Sarkar, Angana, additional, Sarkar, Preetam, additional, Shankar, Shiv, additional, Shehadi, Ihsan, additional, Smandri, Ali, additional, Srivastava, A.K., additional, Sulaiman, Nadiah, additional, Tan, Sheri-Ann, additional, Vellaichamy, Chelladurai, additional, Verma, Sarika, additional, Vosough, Massoud, additional, Yoha, K.S., additional, Zahmatkesh, Ensieh, additional, Zarkesh, Ibrahim, additional, and Zulkiflee, Izzat, additional

Published
2022
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22. Pulmonary Surfactants

Author

Gupta, Anjali, primary, Tripathy, Divya Bajpai, additional, Mishra, Anuradha, additional, and Ghosal, Anujit, additional

Published
2021
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30. Computational/In‐Silico Methods: An Influential Approach for Drug Designing and Development.

Author

Khatana, Kavita, Gupta, Anjali, Ghosal, Anujit, and Zafar, Fahmina

Subjects
DRUG design, DRUG development, VIRUS diseases, COMMUNICABLE diseases, PHARMACISTS
Abstract

As the world is struggling with the pandemic. Various infectious diseases have become a threat to human health. Millions of deaths are caused by these microbial infections (bacterial, fungal, and viral infections). The process of designing and discovering new drugs is very expensive and it also consumes a good amount of time. As per available data, the process of discovery and designing takes 3–20 years to complete. There is a strong urge and demand to discover new methods to make the process of drug design and development more cost‐effective. Computational methods are one the novel methods for designing and developing a drug. In this respect, in‐silico parameters; ADME (Absorption, Distribution, Metabolism, and Excretion) models have been established with various levels of complication for the transmission of huge data of derivatives/ligands/drugs. Nowadays, in‐silico tools are more cost‐effective, faster, and simpler than transitional experimental trials. Currently, the pharmaceutical industry faces a huge erosion rate of preclinical and clinical applicants due to the unavailability of pharmacokinetics properties and huge toxicity. These can be minimized via structural modifications of drugs and can help medicinal chemists/pharmacists. In this report, various methodologies and steps have been explained via molecular docking that will lead to drug development in lesser time against various stains. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Nanotechnology for Therapeutics

Author

Ghosal, Anujit, Vashist, Arti, Tiwari, Shivani, Sharmin, Eram, Ahmad, Sharif, Bhattacharya, Jaydeep, Kaushik, Ajeet, editor, Jayant, Rahul Dev, editor, and Nair, Madhavan, editor

Published
2017
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37. In silicoidentification and validation of phenolic lipids as potential inhibitor against bacterial and viral strains

Author

Khatana, Kavita, Gupta, Anjali, Ghosal, Anujit, Dey, Pinki, Zafar, Fahmina, Srivastava, Anubha, and Verma, Priya

Abstract

AbstractThe recurrence of coronavirus disease and bacterial resistant strains has drawn attention to naturally occurring bioactive molecules that can demonstrate broad-spectrum efficacy against bacteria as well as viral strains. The drug-like abilities of naturally available “anacardic acids” (AA) and their derivatives against different bacterial and viral protein targets through in-silico tools were explored. Three viral protein targets [P DB: 6Y2E (SARS-CoV-2), 1AT3 (Herpes) and 2VSM (Nipah)] and four bacterial protein targets [P DB: 2VF5 (Escherichia coli), 2VEG (Streptococcus pneumoniae), 1JIJ (Staphylococcus aureus) and 1KZN (E. coli)] were selected to evaluate the activity of bioactive AA molecules. The potential ability to inhibit the progression of microbes has been discussed based on the structure, functionality and interaction ability of these molecules on the selected protein targets for multi-disease remediation. The number of interactions, full-fitness value and energy of the ligand-target system were determined from the docked structure in SwissDock and Autodock Vina. In order to compare the efficacy of these active derivatives to that of commonly used drugs against bacteria and viruses, a few of the selected molecules were subjected to 100 ns long MD simulations. It was found that the phenolic groups and alkyl chains of AA derivatives are more likely to bind with microbial targets, that could be responsible for the improved activity against these targets. The results suggest that the proposed AA derivatives have demonstrated potential to become active drug ingredients against microbial protein targets. Further, experimental investigations are essential for clinical verification of the drug-like abilities of AA derivatives.Communicated by Ramaswamy H. Sarma

Published
2024
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43. Contributors

Author

Abitha, V.K., primary, Arun, Thirumurugan, additional, Ashik, U.P.M., additional, Balakrishnan, Raneesh, additional, Bhattacharya, Jaydeep, additional, Devatha, Chella Purushothaman, additional, Ghosal, Anujit, additional, Gobalakrishnan, Suyamprakam, additional, Hayashi, Jun-ichiro, additional, Ho, Li N., additional, Jai Kumar, B., additional, Jayant, Rahul Dev, additional, Kanny, Krishnan, additional, Kaushik, Ajeet, additional, Kudo, Shinji, additional, Lim, Bee Y., additional, Mahesh, H.M., additional, Malwal, Deepika, additional, Bhagyaraj, Sneha Mohan, additional, Nair, Madhavan, additional, Oluwafemi, Oluwatobi Samuel, additional, Packirisamy, Gopinath, additional, Vattikuti, S.V. Prabhakar, additional, Praseetha, Prabhakaran Kala, additional, Rane, Ajay Vasudeo, additional, Ravichandran, Krishnasamy, additional, Kumar, D. Sumanth, additional, Thalla, Arun K., additional, Thankachan, Rahul M., additional, Thomas, Sabu, additional, Tiwari, Shivani, additional, Vashist, Arti, additional, and Voon, Chun H., additional

Published
2018
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45. Design and Engineering of Nanogels

Author

Ghosal, Anujit, primary, Tiwari, Shivani, additional, Mishra, Abhijeet, additional, Vashist, Arti, additional, Rawat, Neha Kanwar, additional, Ahmad, Sharif, additional, and Bhattacharya, Jaydeep, additional

Published
2017
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48. In silico identification and validation of phenolic lipids as potential inhibitor against bacterial and viral strains

Author

Khatana, Kavita, Gupta, Anjali, Ghosal, Anujit, Dey, Pinki, Zafar, Fahmina, Srivastava, Anubha, and Verma, Priya

Subjects
Structural Biology, General Medicine, Molecular Biology
Abstract

The recurrence of coronavirus disease and bacterial resistant strains has drawn attention to naturally occurring bioactive molecules that can demonstrate broad-spectrum efficacy against bacteria as well as viral strains. The drug-like abilities of naturally available “anacardic acids” (AA) and their derivatives against different bacterial and viral protein targets through in-silico tools were explored. Three viral protein targets [P DB: 6Y2E (SARS-CoV-2), 1AT3 (Herpes) and 2VSM (Nipah)] and four bacterial protein targets [P DB: 2VF5 (Escherichia coli), 2VEG (Streptococcus pneumoniae), 1JIJ (Staphylococcus aureus) and 1KZN (E. coli)] were selected to evaluate the activity of bioactive AA molecules. The potential ability to inhibit the progression of microbes has been discussed based on the structure, functionality and interaction ability of these molecules on the selected protein targets for multi-disease remediation. The number of interactions, full-fitness value and energy of the ligand-target system were determined from the docked structure in SwissDock and Autodock Vina. In order to compare the efficacy of these active derivatives to that of commonly used drugs against bacteria and viruses, a few of the selected molecules were subjected to 100 ns long MD simulations. It was found that the phenolic groups and alkyl chains of AA derivatives are more likely to bind with microbial targets, that could be responsible for the improved activity against these targets. The results suggest that the proposed AA derivatives have demonstrated potential to become active drug ingredients against microbial protein targets. Further, experimental investigations are essential for clinical verification of the drug-like abilities of AA derivatives. Communicated by Ramaswamy H. Sarma

Published
2023
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49. Mn(II)‐ and Zn(II)‐ Based Nanocomposites Metallopolymer for Corrosion Protective Coatings.

Author

Alam, Manawwer, Ghosal, Anujit, Zafar, Fahmina, Ahmed, Mukhtar, and Altaf, Mohammad

Subjects
*PROTECTIVE coatings, *TRANSMISSION electron microscopy, *NANOCOMPOSITE materials, *CORN oil, *SCANNING electron microscopy, *IMPEDANCE spectroscopy
Abstract

The transition from conventional polymeric material to green and sustainable, environment‐friendly biomaterials has been actively explored. The objective of the work involves the formulation of an oleo‐polymer (corn oil, CO), hybridization with metallic ions (Zn2+ and Mn2+) through coordination bonding, study of the impact of fully/half‐filled d‐orbitals, and development of eco‐friendly polymeric coating material. The formation of the nanoclusters (10–20 nm) within the polymeric matrix was estimated by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Fourier transform infrared (FTIR) analysis supports the predicted chemical mechanism involved during poly‐urethanation of the metal‐containing CO fatty amides. Interestingly, opposite to our expectations the metal ions with fully filled d‐orbital (Zn2+) showed relatively (Mn2+) better thermal and anti‐corrosion properties. The good adhesive strength of metallopolymers and the impact of the d‐orbital electrons on the corrosion protective performance, which was by electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization (PDP). These nanocomposite coatings could be a suitable alternatives to petrochemical‐based polymers. [ABSTRACT FROM AUTHOR]

Published
2023
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