20 results on '"Ghisu, T"'
Search Results
2. Experimental Investigation on a Speed Controlled Wells Turbine for Wave Energy Conversion
- Author
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Licheri, F., additional, Puddu, P., additional, Cambuli, F., additional, and Ghisu, T., additional
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- 2022
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3. AI-Assisted Strategies for High-Dimensional Optimisation in Turbomachinery
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Lopez, D. I., Ghisu, T., and Shahpar, S.
- Abstract
Presentation of AI-assisted strategiesfor high-dimensional optimisation in turbomachinery at the CM3 Conference in Barcelona (by Diego Lopez)
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- 2022
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4. Global Optimization of a Transonic Fan Blade Through AI-Enabled Active Subspaces
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Lopez, D.I., Ghisu, T., and Shahpar, S.
- Subjects
Mechanical Engineering ,computational fluid dynamics (CFD), fan, compressor, and turbine aerodynamic design - Abstract
The increased need to design higher performing aerodynamic shapes has led to design optimization cycles requiring high-fidelity CFD models and high-dimensional parametrizationschemes. The computational cost of employing global search algorithms on such scenarioshas typically been prohibitive for most academic and industrial environments. In this paper,a novel strategy is presented that leverages the capabilities of artificial neural networks forregressing complex unstructured data, while coupling them with dimensionality reductionalgorithms. This approach enables employing global-based optimization methods on high-dimensional applications through a reduced computational cost. This methodologyis demonstrated on the efficiency optimization of a modern jet engine fan blade with con- strained pressure ratio. The outcome is compared against a state-of-the-art adjoint-based approach. Results indicate that the strategy proposed achieves comparable improvements to its adjoint counterpart with a reduced computational cost and can scale better to multi-objective optimization applications.
- Published
- 2022
5. Effect of on-line hemodiafiltration with endogenous reinfusion (HFR) on the calcium-phosphorus metabolism: medium-term effects
- Author
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BOLASCO, P. G., GHEZZI, P. M., FERRARA, R., MAXIA, M., PINNA, M., LOGIAS, F., COGONI, G., CADINU, F., GHISU, T., CONTU, B., CASU, D., PASSAGHE, M., PILLONI, A., GANADU, M., and GAZZANELLI, L.
- Published
- 2006
6. Evaluation of Entropy Generation Methods in Wells Turbine
- Author
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Licheri, F., primary, Ghisu, T., additional, Virdis, I., additional, Puddu, P., additional, and Cambuli, F., additional
- Published
- 2019
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7. A Critical Examination of the Hysteresis in Wells Turbines Using CFD and Lumped Parameter Models
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Ghisu, T., primary, Cambuli, F., additional, Puddu, P., additional, Virdis, I., additional, Carta, M., additional, and Licheri, F., additional
- Published
- 2019
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8. An Application of the Level-set Method to Fire Front Propagation
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Ghisu T., Arca B., Pellizzaro G., and Duce P.
- Subjects
fire propagation ,level-set ,CFD ,Physics::Atmospheric and Oceanic Physics - Abstract
Wildland fire models and simulators developed in the last two decades are increasingly applied in different ecosystems and countries of the world to predict fire behaviour and effects. Fire models range from empirical formulas, such as the ones defined by Rothermel [1] and applied in spatially and temporally explicit fire simulators (i.e. Farsite), to complex three-dimensional CFD approaches solving the partial differential equation of continuity, momentum and energy. The wide range of length and time scales governing wildland fire (from the millimeter scale of combustion processes to the hundreds of meters scale of synoptic wind flow) complicates the use of a full-3D numerical approach, at least for operational forecasting purposes. At the same time, there is an important two-way influence between weather and fire: wind determines fire propagation and, conversely, the buoyancy effects generated by fire heat modify the local wind field, -creating their own weather?. A possible solution to this problem is the use of a simpler (and thus computationally cheaper) model to describe fire propagation, while maintaining a CFD approach to model wind behaviour and, more importantly, the two-way interaction due to fire heat release. A number of studies applied this approach in the last few years. This work describes the initial steps in the development of a model for fire-front propagation based on a level-set methodology and its integration into a CFD model.
- Published
- 2012
9. Automatic optimisation to improve wind field predictions
- Author
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Ghisu T., Arca B., Pellizzaro G., Ventura A., Arca A., and Duce P.
- Subjects
wind predictions ,CFD - Abstract
A number of studies have reported on the application of computational fluid dynamics (CFD) models to produce high resolution data of wind flow. CFD models are based on the numerical solution of a number of partial differential equations expressing conservation of mass, momentum and energy (when buoyancy effects are not negligible) and make use of a number of simplifications (turbulence models) to reduce the range of length scales which are directly resolved. Most of these works validate the proposed approaches in simplified domains, where separated flows and recirculation regions are limited. In addition, application of CFD models requires a precise specification of both simulation domain characteristics and boundary conditions (in terms of flow direction and intensity); unfortunately, especially in areas characterised by complex terrains, measured data of wind intensity and direction collected close to the limits of the computational domain (fundamental to prescribe appropriate boundary conditions) are often not available. The aims of this work were (1) to develop a methodology for simulating wind flow in domains with complex orography, by matching data within the domain, (2) to compare wind fields predicted by different commercial or open-source software and (3) to validate the simulation results on a set of experimental data collected in different areas of the computational domain. More specifically, CFD simulations were linked to an automatic optimisation system developed by the authors based on a pattern search algorithm, which attempts to minimise two functions (deviation of wind speed and direction) at a number of prescribed locations within the domain where experimental data are available. A kriging approximation was used to accelerate convergence to a minimum. The study demonstrates the capabilities of the proposed approach in simulating wind flow in areas characterised by a complex topography and uncertainty in boundary conditions.
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- 2011
10. Expected impacts of climate change on live fuel moisture content in Mediterranean shrub species
- Author
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Pellizzaro G., Ventura, Arca B., Ghisu T., Masia P., and Duce P.
- Abstract
According to recent projections on future climate, an increase in risk of summer droughts in both Central and Southern Europe is expected. The most pronounced warming is likely to take place in the Mediterranean area in summer when the highest temperatures occur. In addition, annual precipitation and the annual number of rainy days are very likely to decrease in most of the Mediterranean Basin. More prolonged drought seasons induced by climatic changes are likely to influence general flammability characteristics of fuel, affecting load distribution in vegetation strata, floristic composition, and live and dead fuel ratio. In addition, variations in precipitation and mean temperature could directly affect the fuel water status, and consequently flammability, and length of critical periods of high ignition danger for Mediterranean ecosystems. Mediterranean shrub species are an important component of both Mediterranean vegetation communities and understorey vegetation. They also constitute the surface fuels primarily responsible for the ignition and the spread of wildland fires in Mediterranean forests. Although fire spread and behaviour are dependent on several factors, the water content of live fuel plays a crucial role in determining wildland fire danger, especially in the Mediterranean shrubland, where live fuel is often the main component of the available fuel which catches fire. Several studies have proved the relation between live fuel moisture content (FMC) and flammability and have verified the relations between live FMC and actual fire occurrence. Considering the observed climatic variations and foreseen future scenarios, an evaluation of the impact of these variations on fire danger seems essential. Therefore, the main aims of this work are i) to identify useful tools to determine possible impacts of expected climate change on fuel status in Mediterranean shrublands, and ii) to predict the potential impacts of climate change on the length of fire danger season due to live fuel status. The study was carried out in Sardinia (Italy). Moisture content of live fuel was determined periodically during five years on four shrub species (Cistus monspeliensis L., Juniperus phoenicea L, Pistacia lentiscus L., and Rosmarinus officinalis L.). Meteorological variables were also recorded. Data sets were used to determine the accuracy of meteorological drought codes in estimating live fuel moisture patterns in Mediterranean areas. Threshold values of codes for estimating the starting and ending dates of high ignition danger periods were estimated by percentile and logistic analysis. Finally, a methodology to identify the length of critical periods of high ignitability risk in maquis ecosystems was proposed. Potential climate change impact on length of ignition danger season in Mediterranean Basin shrublands was determined using the meteorological code values and future climate scenarios at a local scale derived from an advanced high resolution Regional Climate Model. Starting and ending dates of danger season were calculated for the period May-October using data from the Regional Climate Model (1961 - 1990: baseline; 2071 - 2100 A1B scenario). Changes in length of fire danger season due to live fuel water content were finally analysed. Results suggest that future climate projections could determine changes in fuel moisture dynamics and affect the duration of the danger fire season causing a delay in the ending dates of high ignition danger periods.
- Published
- 2011
11. Improving computational predictions of wind field by automatic optimization
- Author
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Ghisu T., Arca B., Pellizzaro G., Arca A., Ventura A., and Duce P.
- Abstract
Wildland fire models and simulators developed in the last twenty years are increasingly applied in different ecosystems and countries of the world in order to predict fire behaviour and effects, and to support fire prevention and management programs. In addition to the simplifications and preliminary assumptions of fire spread models, which are mainly based on a semi-physical approach, criticisms of fire simulators frequently concern the need of high resolution environmental data (fuel model maps, canopy cover, etc.), and in particular data on environmental variables that quickly change in space and time (e.g. wind speed and direction). The rapid increase in computational resources and numerical methods of the last years helps to provide high temporal and spatial resolution data on wind fields in order to improve the accuracy of simulations at both local and regional scale. Several studies report on the application of computational fluid dynamics (CFD) models to produce high resolution data of wind flow. CFD models are based on the numerical solution of a number of partial differential equations expressing conservation of mass, momentum and energy (when buoyancy effects are not negligible) and make use of a number of simplifications (turbulence models) to reduce the range of length scales which are directly resolved. Most of these works validate the proposed approaches in simplified domains, where separated flows and circulation regions are limited. In addition, application of CFD models requires a precise specification of both simulation domain characteristics and boundary conditions (in terms of flow direction and intensity); unfortunately, especially in areas characterized by complex terrains, measured data of wind intensity and direction collected close to the limits of the computational domain (fundamental to prescribe appropriate boundary conditions) are often not available. The aims of this work were (1) to develop a methodology for simulating wind flow in domains with complex orography, by matching data within the domain, (2) to compare wind fields predicted by different commercial or open-source software and (3) to validate the simulation results on a set of experimental data collected in different areas of the computational domain.
- Published
- 2011
12. HAEMODIALYSIS TECHNIQUES AND ADEQUACY 2
- Author
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Chamney, P., primary, Moissl, U., additional, Wabel, P., additional, Amato, C., additional, Stuard, S., additional, Menzer, M., additional, Vollmeier, C., additional, Williams, G., additional, Shrivastava, R., additional, Chess, J., additional, Catling, E., additional, Brown, C., additional, Baker, E., additional, Ashcroft, R., additional, Mikhail, A., additional, Djukanovic, L., additional, Djuric, Z., additional, Knezevic, V., additional, Lazarevic, T., additional, Ljubenovic, S., additional, Markovic, R., additional, Rabrenovic, V., additional, Marinkovic, J., additional, Dimkovic, N., additional, Lebourg, L., additional, Ridel, C., additional, De Preneuf, H., additional, Le Roy, F., additional, Petitclerc, T., additional, Wester, M., additional, Simonis, F., additional, Kooman, J. P., additional, Boer, W. H., additional, Gerritsen, K. G. F., additional, Joles, J. A., additional, Yamamoto, K.-i., additional, Eguchi, K., additional, Hirakawa, S., additional, Murakami, J., additional, Akiba, T., additional, Mineshima, M., additional, Stamopoulos, D., additional, Mpakirtzi, N., additional, Lavranos, A., additional, Panagiotou, M., additional, Barbarousi, D., additional, Matsouka, C., additional, Grapsa, E., additional, Abbas, S. R., additional, Zhu, F., additional, Kaysen, G. A., additional, Kotanko, P., additional, Levin, N. W., additional, Vasilevsky, A., additional, Konoplev, G., additional, Stepanova, O., additional, Rubinsky, A., additional, Zemchenkov, A., additional, Gerasimchuk, R., additional, Frorip, A., additional, Abe, T., additional, Yamamoto, K.-I., additional, Ishimori, I., additional, Kusztal, M., additional, Go Biowski,, T., additional, Letachowicz, K., additional, Koni Ski, P., additional, Witkowski, G., additional, Pozna Ski, P., additional, Weyde, W., additional, Klinger, M., additional, Ito, M., additional, Ito, S., additional, Suzuki, M., additional, Masakane, I., additional, Navarro, D., additional, Goncalves, C., additional, Ferreira, A. C., additional, Jorge, C., additional, Gil, C., additional, Aires, I., additional, Matias, P., additional, Mendes, M., additional, Azevedo, A., additional, Gomes, F., additional, Ferreira, A., additional, Perazzini, C., additional, Scutiero, L., additional, Brighenti, L., additional, Surace, A., additional, Steckiph, D., additional, Rovatti, P., additional, Severi, S., additional, Soltysiak, J., additional, Warzywoda, A., additional, Musielak, A., additional, Ostalska-Nowicka, D., additional, Zachwieja, J., additional, Goeksel, T., additional, Garnier, H., additional, Ritzerfeld, M., additional, Mann, H., additional, Babinet, F., additional, Allard, B., additional, Todorova, V., additional, Hamont, C., additional, Begri, R., additional, Dekker, M., additional, Taks, M., additional, Konings, C., additional, Scharnhorst, V., additional, Borawski, J., additional, Gozdzikiewicz-Lapinska, J., additional, Naumnik, B., additional, Lodi, C. A., additional, Grandi, E., additional, Mancini, E., additional, Santoro, A., additional, Sereni, L., additional, Caiazzo, M., additional, Corazza, L., additional, Atti, M., additional, Palladino, G., additional, Sakurai, K., additional, Saito, T., additional, Hosoya, H., additional, Yamauchi, F., additional, Kurihara, T., additional, Tanibayashi, Y., additional, Ikebe, N., additional, Antonic, M., additional, Gubensek, J., additional, Drozg, A., additional, Vannier, E., additional, Mattio, E., additional, Ragon, A., additional, Brunet, P., additional, Klimm, W., additional, Pleskacz, K., additional, Pietrzak, B., additional, Niemczyk, S., additional, Leypoldt, J. K., additional, Bernardo, A., additional, Muller, M., additional, Marbury, T. C., additional, Culleton, B. F., additional, Zeraati, A. A., additional, Hekmat, R., additional, Reyhani, H. R., additional, Sharifipoor, F., additional, Bolasco, P., additional, Sitzia, I., additional, Monni, A., additional, Mereu, M. C., additional, Pinna, A. M., additional, Logias, F., additional, Ghisu, T., additional, Passaghe, M., additional, Gazzanelli, L., additional, Ganadu, M., additional, Piras, A., additional, Cossu, M., additional, Contu, B., additional, Palleschi, S., additional, Rossi, B., additional, Ghezzi, P. M., additional, Kron, S., additional, Schneditz, D., additional, Leimbach, T., additional, Aign, S., additional, Kron, J., additional, Seker Kockara, A., additional, Kayatas, M., additional, Huzmeli, C., additional, Candan, F., additional, Yilmaz, M. B., additional, Ahmed, B. A., additional, Bejosano, C. N., additional, Samra Abouchacra, S. A., additional, Al Falahi, S. Z., additional, Abdul Moniem, K. M., additional, Dastoor, H., additional, Kim, S., additional, Oh, J., additional, Sin, Y., additional, Kim, J., additional, and Lee, J., additional
- Published
- 2014
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13. Hemodiafiltration with Endogenous Reinfusion with and without Acetate-Free Dialysis Solutions: Effect on ESA Requirement
- Author
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Bolasco, P.G., primary, Ghezzi, P.M., additional, Serra, A., additional, Corazza, L., additional, Murtas, S., additional, Mascia, M., additional, Cossu, M., additional, Ferrara, R., additional, Cogoni, G., additional, Cadinu, F., additional, Casu, D., additional, Contu, B., additional, Passaghe, M., additional, Ghisu, T., additional, Ganadu, M., additional, and Logias, F., additional
- Published
- 2011
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14. Predilution haemofiltration--the Second Sardinian Multicentre Study: comparisons between haemofiltration and haemodialysis during identical Kt/V and session times in a long-term cross-over study.
- Author
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Altieri, P, Sorba, G, Bolasco, P, Asproni, E, Ledebo, I, Cossu, M, Ferrara, R, Ganadu, M, Cadinu, F, Serra, G, Cabiddu, G, Sau, G, Casu, D, Passaghe, M, Bolasco, F, Pistis, R, and Ghisu, T
- Abstract
The potential superiority of various renal replacement treatment modalities consisting largely of convective mass transfer as opposed to primarily diffusive mass transfer, is still a matter of debate. The objective of the present study was to evaluate acute and long-term clinical effects of varying degrees of convection and diffusion in a group of 24 clinically stable patients with end-stage renal disease.
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- 2001
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15. Adequacy in pre-dilution haemofiltration: Kt/V or infusion volume?
- Author
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Bolasco, P., Altieri, P., Sorba, G., Cabiddu, G., Ferrara, R., Serra, G., Cadinu, F., Passaghe, M., Piras, A., Calvisi, L., Pistis, R., and Ghisu, T.
- Abstract
Kt/V is the main index of adequacy for diffusive and diffusive-convective methods of extracorporeal depuration, yet there exists no universally acceptable validation of an adequacy index for the solely convective methods such as haemofiltration (HF). The aim of the present study is to analyse which of the parameters of adequacy used in two multicentre HF studies, Kt/V for urea or infusion volume, correlate best with nutritional parameters and can therefore be utilized for the evaluation of treatment dose in on-line pre-dilution HF.Twenty-three clinically stable patients were enrolled in the first study [3 months of haemodialysis (HD)+3 months of HF]. In the second study, 24 stable patients were studied in three phases: 6 months in HF, 6 months in HD and a further 6 months in HF; in this study, a target of Kt/V=1.2 in all three periods was pre-established: 15 patients completed the full study. In both studies, we utilized the same monitor (AK 100/200 Ultra, Gambro), the same membrane (polyamide) and the same on-line prepared ultrapure dialysis fluid and sterile infusion solution.In both studies, we ensured that HF fulfilled the following parameters of adequacy: urea kinetics, cardiovascular and blood pressure stability (better in HF than in HD), common haematochemical and nutritional parameters, reduction in β2-microglobulin levels, a good intra- and extra-session clinical outcome, and a good quality of life with morbidity and mortality rates no different from those of HD.HF proved to be an efficacious method of ensuring adequate depuration and a good quality of life for uraemic patients. We have shown that in longer periods of HF, a notable correlation between Kt/V and normalized protein catabolic rate (nPCR) and an equally good correlation between total ultrafiltration (UF)/dry weight ratio and nPCR could be achieved. In both studies, the patients showed a good level of epuration adequacy when total UF per session was at least 1.3 times the dry body weight. The total UF/body weight ratio thus seems to be an easy method in HF because of its greater ease of predictability and measurement, also when it is used independently of the Kt/V index.
- Published
- 2000
16. Pre-dilution haemofiltration--the Sardinian multicentre studies: present and future
- Author
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Cadinu, F., Calvisi, L., Cabiddu, G., Galfré, A., Serra, G., Casu, D., Bolasco, F., Passaghe, M., Ghisu, T., Sau, G., Ginanni, A., Pistis, R., Altieri, P., Sorba, G., Bolasco, P., Asproni, E., Ledebo, I., Boström, M., Ferrara, R., Ganadu, M., and Cossu, M.
- Published
- 2000
17. An investigation of higher-order multi-objective optimisation for 3D aerodynamic shape design
- Author
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Timoleon Kipouros, Ghisu, T., Parks, G. T., and Savill, A. M.
18. A level-set algorithm for simulating wildfire spread
- Author
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Ghisu, T., Arca, B., Pellizzaro, G., and Pierpaolo Duce
- Subjects
Huygens principle ,cellular automata ,level-set ,Wildfire spread - Abstract
Level-set approaches are efficient and versatile methods for solving interface tracking problems and have been used in recent years to describe wildland fire propagation. Being based on an Eulerian description of the spread problem, their numerical implementation offers improved computational agility and better portability to parallel computing environments with respect to vector-based simulators. The use of a continuous representation of the fire perimeter in place of the binary formulation used in Cellular Automata avoids the commonly observed distortion of the fire shape. This work presents an algorithm for fire-spread simulation based on a level-set formulation. The results are compared to the ones obtained by two well-known Cellular Automata simulators under homogeneous conditions, and to the ones given by a well-know vector-based fire-spread simulator under realistic slope and wind conditions. According to this work, the level-set approach provides better results, in terms of accuracy, at a much reduced computational cost.
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19. Vitamins (A, C and E) and oxidative status of hemodialysis patients treated with HFR and HFR-Supra.
- Author
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Palleschi S, Ghezzi PM, Palladino G, Rossi B, Ganadu M, Casu D, Cossu M, Mattana G, Pinna AM, Contu B, Ghisu T, Monni A, Gazzanelli L, Mereu MC, Logias F, Passaghe M, Amore A, and Bolasco P
- Subjects
- Adult, Advanced Oxidation Protein Products blood, Aged, Aged, 80 and over, Cross-Over Studies, Female, Humans, Lipids blood, Male, Middle Aged, Oxidative Stress, Prospective Studies, Retinol-Binding Proteins, Plasma metabolism, Young Adult, Antioxidants metabolism, Ascorbic Acid blood, Hemodiafiltration methods, Kidney Failure, Chronic therapy, Vitamin A blood, Vitamin E blood
- Abstract
Background: Hemodiafiltration with on-line endogenous reinfusion (HFR) is an extracorporeal dialytic method that combines diffusion, convection and adsorption. HFR-Supra (HFR-S) is a second-generation system with increased convective permeability and adsorption capability. Previous studies suggested that HFR reduces oxidative stress compared to standard haemodialysis. The principal aim of the present study was to compare antioxidant vitamins behavior and oxidative status of hemodialysis patients treated with HFR and HFR-S., Methods: The study was designed as a multicenter, randomized, crossover trial. Forty-one patients were recruited from 19 dialysis centers and after a 4-month washout stabilization period in on-line hemodiafiltration (ol-HDF), each patient was randomized to a sequence of treatments (HFR-S followed by HFR or viceversa) with each treatment applied over 6 months. Plasma levels of Advanced Oxidation Protein Products, Total Antioxidant Status, vitamins C, A and E and their ligands (Retinol Binding Protein and total lipids) were measured at baseline and at the end of each treatment period., Results: Results show that the higher convective permeability of HFR-S with respect to HFR did not produce additional beneficial effects on the patients' oxidative status, a slight decrease of both Vitamin A and Retinol Binding Protein being the only difference registered in the long-term. However, as compared to ol-HDF, both the re-infusive techniques allowed to reduce the intradialytic loss of Vitamin C and, in the long-term, improve the patients' oxidative status and increase Retinol Binding Protein plasma values. No significant differences were found between the Vitamin C concentration of pre- and post cartridge UF neither in HFR-S nor in HFR showing that the sorbent resin does not adsorb Vitamin C., Conclusion: HFR-S and HFR are almost equivalent in term of impact on antioxidant vitamins and oxidative status of hemodialysis patients. Nonetheless, as compared to ol-HDF, both treatments produced a sensible sparing of Vitamin C and may represent a new approach for reducing oxidative stress and related complications in dialysis patients. Long-term effects of re-infusive treatments on patients' cardiovascular morbidity and mortality need to be evaluated., Trial Registration: ClinicalTrials.gov Identifier NCT01492491 , retrospectively registered in 10 December 2011.
- Published
- 2016
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20. Pre-dilution haemofiltration--the Sardinian multicentre studies: present and future. The Sardinian Collaborative Study Group on Haemofiltration On-Line.
- Author
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Altieri P, Sorba G, Bolasco P, Asproni E, Ledebo I, Boström M, Ferrara R, Ganadu M, Cossu M, Cadinu F, Cabiddu G, Serra G, Casu D, Bolasco F, Passaghe M, Ghisu T, Sau G, Ginanni A, Pistis R, Calvisi L, and Galfré A
- Subjects
- Adult, Aged, Cross-Over Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Renal Dialysis, Urea metabolism, Hemofiltration
- Published
- 2000
- Full Text
- View/download PDF
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