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267 results on '"Gheith, Osama A"'

10. #3003 IMPACT OF FULL CORRECTION OF HEMOGLOBIN AMONG POST-TRANSPLANT ANEMIC KIDNEY TRANSPLANT RECIPIENTS: A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL

Author

Alotaibi, Torki, primary, Gheith, Osama Ashry Ahmed, additional, Nagib, Ayman Maher, additional, Abdulhalim, Medhat, additional, Aboatya, Hasaneen Hasaneen Ahmed Aboatya, additional, Mahmoud, Tarek S H, additional, Nair, Prasad, additional, Adel, Hany, additional, Mosaad, Ahmed, additional, Atta, Ahmed, additional, and Abdulhamed, Mohamed, additional

Published
2023
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11. #3895 COMPARABLE RENO-CARDIAC PROTECTIVE EFFECTS OF SGLT2 INHIBITION VERSUS DPP-4 INHIBITION IN DIABETIC KIDNEY TRANSPLANT RECIPIENTS: KUWAIT EXPERIENCE

Author

Alotaibi, Torki, primary, Gheith, Osama Ashry Ahmed, additional, Elsayed, Zakaria, additional, Yahya, Ahmed, additional, Shaker, Mohamed, additional, Khalid, Mahmoud, additional, Emam, Mohamed, additional, Hammad, Muhammad, additional, Nagib, Ayman Maher, additional, Mostafa, Mohamed, additional, Denewar, Ahmed, additional, Zahab, Mohamed Ahmed Abdulkhalek, additional, Nair, Prasad, additional, Elserwy, Nashwa, additional, and Elserwy, Nabil, additional

Published
2023
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22. Diabetic kidney disease: world wide difference of prevalence and risk factors

Author

Gheith Osama, Farouk Nashwa, Nampoory Narayanan, Halim Medhat A, and Al-Otaibi Torki

Subjects
Diabetic kidney disease, End-stage kidney disease, Glomerular filtration rate, Type 2 diabetes, Microalbuminuria, Chronic kidney disease, Therapeutics. Pharmacology, RM1-950, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Diabetic kidney disease – which is defined by elevated urine albumin excretion or reduced glomerular filtration rate (GFR) or both – is a serious complication that occurs in 20% to 40% of all diabetics. In this review we try to highlight the prevalence of diabetic nephropathy which is not uncommon complication of diabetes all over the world. The prevalence of diabetes worldwide has extended epidemic magnitudes and is expected to affect more than 350 million people by the year 2035. There is marked racial/ethnic besides international difference in the epidemiology of diabetic kidney disease which could be explained by the differences in economic viability and governmental infrastructures. Approximately one-third of diabetic patients showed microalbuminuria after 15 years of disease duration and less than half develop real nephropathy. Diabetic kidney disease (DKD) is more frequent in African-Americans, Asian-Americans, and Native Americans. Progressive kidney disease is more frequent in Caucasians patients with type 1 than type 2 diabetes mellitus (DM), although its overall prevalence in the diabetic population is higher in patients with type 2 DM while this type of DM is more prevalent. Hyperglycemia is well known risk factor for in addition to other risk factors like male sex, obesity, hypertension, chronic inflammation, resistance to insulin, hypovitaminosis D, and dyslipidemia and some genetic loci and polymorphisms in specific genes. Management of its modifiable risk factors might help in reducing its incidence in the nearby future.

Published
2016

23. P8.023: Acute Kidney Injury Among COVID-19 Positive Patients Is Associated With Higher Mortality: Single Center Experience

Author

AlOtaibi, Torki M., primary, Gheith, Osama, additional, Nagib, Ayman M., additional, Alserwy, Nabil, additional, Abbas, Ahmad M., additional, Elsawi, Islam S., additional, Nair, Prasad, additional, khaled, Mahmoud M., additional, Hammad, Mohamed A., additional, Fayyad, Zohair A., additional, Atta, Ahmed F., additional, Mostafa, Ahmed Y., additional, Deraz, Ahmed S., additional, and Moneim, Mohamed A., additional

Published
2022
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25. P8.025: Impact of Full Correction of Post-transplant Anemia on the Cardiovascular System in Renal Transplant Recipients Receiving Erythropoietin Stimulating Agents: Prospective Randomized Controlled Trial

Author

Al-Otaibi, Torki, primary, Gheith, Osama, additional, Najeeb, Ayman M., additional, halim, Medhat A., additional, Abo-Atteya, Hasanein, additional, Mahmoud, Tarek, additional, Prasad, Nair, additional, Adel, Hany, additional, Mosaad, Ahmed, additional, Fathy, Ahmed, additional, and Abdul-Hameed, Mohamed, additional

Published
2022
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27. P8.021: Study the Effect of Sodium-Glucose Cotransporter-2 Inhibition Versus Dipeptidyl Peptidase-4 Inhibition in Diabetic Kidney Transplant Recipients

Author

Aotaibi, Torki, primary, Gheith, Osama, additional, Elsayed, Zakaria, additional, Yahya, Ahmed, additional, Shaker, Mohamed, additional, Khalid, Mahmoud, additional, Emam, Mohamed, additional, Mostafa, Mohamed, additional, Abdul-Hameed, Mohamed, additional, Maher, Ayman, additional, Denewar, Ahmed, additional, Dahab, Mohamed, additional, Elserwy, Nabil, additional, Othman, Nashwa, additional, and Nair, Prasad, additional

Published
2022
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29. P16.08: COVID-19 Positive Kidney Transplant Recipients Behave Differently Compared to Non-transplant Patients ICU: Single Center Experience

Author

Gheith, Osama, primary, Nagib, Ayman M., additional, Alserwy, Nabil, additional, Emam, Mohamed, additional, Abuelmagd, Mohamed M., additional, Adel, Mohamed, additional, Al-Qallaf, Ahmed K., additional, Shaker, Mohamed, additional, Abbas, Ahmad M., additional, Halim, Medhat A., additional, Said, Tarek, additional, Nair, Prasad, additional, khaled, Mahmoud M., additional, Hammad, Mohamed A., additional, Fayyad, Zohair A., additional, Atta, Ahmed F., additional, Mostafa, Ahmed Y., additional, Deraz, Ahmed S., additional, Zakaria, Zakaria E., additional, Atea, Khaled A., additional, Aboatya, Hasaneen H., additional, Ameenn, Mohamed E., additional, Moneim, Mohamed A., additional, Mahmoud, Amro M., additional, and AlOtaibi, Torki M., additional

Published
2022
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32. MO973: Optimization of Erythropoietin Stimulating Agents for Post-Transplant Anemia in Kidney Recipients: Prospective Randomized Controlled Trial

Author

Alotaibi, Torki, primary, Ashry Ahmed Gheith, Osama, additional, MA Halim, Medhat, additional, Maher Nagib, Ayman, additional, Hasaneen Ahmed Aboatya Aboatya, Hasaneen, additional, S.H. Mahmoud, Tarek, additional, Nair, Prasad, additional, Atta, Ahmed, additional, Abdelmonem, Mohamed, additional, and Nampoory, Narayanam, additional

Published
2022
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33. MO297: Acute Kidney Injury Among COVID-19 Positive Patients is Associated With Higher Mortality: Single Center Experience

Author

Ashry Ahmed Gheith, Osama, primary, Maher Nagib, Ayman, additional, Elserwy, Nabil, additional, Abbas, Ahmad, additional, Elsawi, Islam S, additional, Nair, Prasad, additional, Khalid, Mahmoud, additional, Hammad, Mohamed, additional, Fayyad, Zohair, additional, Atta, Ahmed, additional, Mostafa, Ahmed, additional, Deraz, Ahmed, additional, Abdelmonem, Mohamed, additional, and Alotaibi, Torki, additional

Published
2022
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40. Disseminated Rhinocladiella mackenziei infection in a kidney transplant recipient: A case report and literature review

Author

AlOtaibi, Torki M, primary, Gheith, Osama A, additional, Alobaid, Khaled, additional, Nair, Prasad, additional, Eldein, Sohair M Zein, additional, Mahmoud, Tarek S, additional, Halim, Medhat A, additional, Aboatya, Hasaneen H, additional, Balaha, Mohamed A, additional, Atea, khalid A, additional, Nagib, Ayman Maher, additional, Al-Hatmi, Abdullah M.S., additional, Sadon, Amal, additional, Meis, Jacques F., additional, and Zahab, Mohamed, additional

Published
2021
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41. Comparative Analysis of Azathioprine versus Cyclosporine-based Therapy in Primary Haplo-identical Live-Donor Kidney Transplantation: A 20-Year Experience

Author

Gheith Osama, Bakr Mohamed, Fouda Mohamed, Shokeir Ahmed, Sobh Mohamed, and Ghoneim Mohamed

Subjects
Medicine
Abstract

Chronic allograft nephropathy (CAN) remains a major cause of graft failure over the long term, second only to patient mortality. The main adverse effects of cyclosporine A (CsA) include nephrotoxicity, hypertension, symptomatic hyperuricemia, hirsutism, and gum hyperplasia. Available studies among live related donor renal transplants lack adequate information regarding the long-term efficacy and safety of primary CsA-based immunosuppressive regimens. This prospective randomized study is aimed at evaluating the long-term results of CsA-based immunosuppressive protocols in live-donor kidney transplantation. The follow-up data of 444 renal transplant recipients operated at the Urology and Nephrology Center, Mansoura University, prior to 1996 were reviewed. Primary immuno-suppressive protocols included: steroids and azathioprine (group I, 130 cases); steroids and CsA (group II, 75 cases); and steroids, CsA, and azathioprine (group III, 239 cases). Only adult primary renal transplant recipients with age ranging between 18 and 60 years and one haplotype HLA mismatch with the donor were included. All patients received kidneys from living related donors with previous donor non-specific blood transfusions. The percentage of cases with chronic rejection was significantly higher in group III. Living cases with graft failure were significantly higher in group III, whereas mortality was significantly higher in group I. Diabetic patients and those with serious bacterial infections were significantly more prevalent in group II. Hypertensive patients were significantly more common in groups I and II. Liver disease was more prevalent among patients in group III. Our study suggests that the long-term results of treatment with steroids and azathioprine are satisfactory in live related donor kidney transplant recipients. Chronic rejection was significantly higher in patients in group III, possibly due to the risk of CsA nephrotoxicity. Groups with CsA-based protocols experienced many adverse reactions of CsA such as hypertension, diabetes mellitus, and chronic rejection

Published
2008

42. Contrast-induced Nephropathy in Kidney Transplant Recipients: A Single-center Experience.

Author

Gheith, Osama A., Nagib, Ayman M., Halim, Medhat A., Mahmoud, Tarek, Nair, Prasad, Abo-Atya, Hasaneen, Shaker, Mohamed, Mostafa, Mohamed, Attia, Hosam, and Torki Al-Otaibi

Subjects
*CONTRAST induced nephropathy, *DIABETIC nephropathies, *KIDNEY transplantation, *CHRONIC kidney failure, *MYOCARDIAL ischemia, *CORONARY disease
Abstract

Introduction. Data regarding contrast-induced nephropathy (CIN) in kidney transplant (KT) recipients are scarce despite the distinct risk factors such as the use of immunosuppressive agents, sympathetic denervation, glomerular hyperfiltration, and high prevalence of the cardiovascular disease. This study aimed to determine the prevalence of CIN in KT recipients who received low-osmolality iodine-based contrast material (CM) for radiological assessment. Methods. Between 2010 and 2020, 79 of the 3180 KT recipients followed at Hamed Al-Essa organ transplant center received low-osmolality iodine-based contrast for radiological assessment for various indications. Preventive measures including holding metformin, intravenous hydration, sodium bicarbonate and N-acetylcysteine were given before contrast administration. CIN was defined as an increase in serum creatinine of 25% from the baseline within 72 hours. Results. The enrolled patients were divided into two groups: those who developed CIN (n = 7) and those with no increase in serum creatinine level (n = 72). The mean age of the patients was 52.1 ± 12.3 years; 44 of them were males, and the cause of end-stage kidney disease was mostly diabetic nephropathy. The pre-transplant demographics were comparable between the two groups. Fortyseven cases received contrast for coronary angiography, and 32 received it for a CT scan. The graft function deteriorated in group 1, but no significant difference was found between the two groups at the end of the study. Conclusion. CIN is not uncommon in KT recipients receiving CM, especially with ischemic heart disease. Risk stratification, optimizing hemodynamics, and avoiding potential nephrotoxins are essential before performing CM-enhanced studies in KT recipients. [ABSTRACT FROM AUTHOR]

Published
2023
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44. Medication compliance and lifestyle adherence in renal transplant recipients in Kuwait

Author

Kenawy,Ahmed Saleh, Gheith,Osama, Al-Otaibi,Torky, Othman,Nashwa, Abo Atya,Hasaneen, Al-Otaibi,Mohamed, and Nagy,Mohamed Sobhy

Subjects
Patient Preference and Adherence, Kuwait, renal transplant, compliance, Original Research
Abstract

Ahmed Saleh Kenawy,1 Osama Gheith,1 Torky Al-Otaibi,1 Nashwa Othman,2 Hasaneen Abo Atya,1 Mohamed Al-Otaibi,1 Mohamed Sobhy Nagy31Hamed Al-Essa Organ Transplant Center, Ibn Sina Group of Hospitals, Ministry of Health, Kuwait City, Kuwait; 2Dasman Diabetes Institute, Ministry of Health, Kuwait City, Kuwait; 3Kuwait Cancer Center, Ministry of Health, Kuwait City, KuwaitCorrespondence: Ahmed Saleh KenawyHamed Al-Essa Organ Transplant Center, Ibn Sina Group of Hospitals, Pharmacy Department, Sabah Medical Area, Shuwikh, PO Box 25427, Kuwait City, Safat 13115, KuwaitTel +965 9 755 7486Email Akenawy01@qub.ac.ukIntroduction and aim: Kidney transplantation is the optimal treatment choice for end stage renal disease; this option needs a major change in the recipients’ lifestyle and requires strict adherence to medications. The study aim was to assess the compliance of renal transplant patients to medications and lifestyle modifications in the Hamed Al-Essa Organ Transplant Center in Kuwait.Patients and methods: One-hundred and twenty renal transplant patients were interviewed for their lifestyle behaviors after transplantation, including transplant adherence to their medications, healthy meals, personal hygiene, physical activity, regular out-patient follow up visits, and preventive measures against infection and cancer, in addition to sexual function. The questionnaire used was created by staff of the Faculty of Medicine, Mansura University, Egypt.Results: Sixty percent of the renal transplant patients were compliant with medications and lifestyle. Risk factors associated with poor medication compliance were being Kuwaiti citizens, women, and having had unrelated living donors (p

Published
2019

45. Immunogenetics of new onset diabetes after transplantation in Kuwait

Author

Jahromi,Mohamed, Al-Otaibi,Torki, Othman,Nashwa, Gheith,Osama, Mahmoud,Tarek, Nair,Prasad, Halim,Medhat A, and Nampoory,Narayanam

Subjects
immunosuppression, NODAT, ethnicity, Targets and Therapy [Diabetes, Metabolic Syndrome and Obesity], Original Research, transplantation
Abstract

Mohamed Jahromi,1 Torki Al-Otaibi,2 Nashwa Othman,3 Osama Gheith,2 Tarek Mahmoud,2 Prasad Nair,2 Medhat A Halim,2 Narayanam Nampoory1,21Clinical Research, Medical Division, Dasman Diabetes Institute, Kuwait City, Kuwait; 2Nephrology Department, Hamid Al-Essa Organ Transplant Center, Kuwait City, Kuwait; 3Education, Clinical Services Division, Dasman Diabetes Institute, Kuwait City, KuwaitIntroduction and aim: New onset diabetes after transplantation (NODAT) is a serious metabolic complication following kidney transplantation. Although beta-cell dysfunction is considered the main contributing factor in the development of this complication, its exact etiology is yet to be identified. We aimed to investigate NODAT among kidney transplant cohort in Kuwait with special stress on correlation between its risk factors and interferon gamma genotyping.Materials and methods: We surveyed 309 kidney transplant recipients from Hamed Al Essa Transplantation Centre, Kuwait. The participants were categorized into cohorts according to the development of NODAT diagnosed based on the American Diabetes Association guidelines. Statistical analyses were performed using SPSS software. We genotyped interferon gamma as the leading immunosignature for T lymphocyte.Results: No relationship between ethnicity and the development of NODAT was identified. However, there was a significant difference in age between cohorts. Younger patients demonstrated a lower rate of NODAT while, NODAT reached its maximum in 40–60-year age group. IFNG TT genotype was significantly associated with NODAT (p=0.005), while IFNG AA was considerably higher in the non-NODAT group.Conclusion: Beside the conventional contributing factors of NODAT, our results might represent a suitable platform for a larger cytokine and chemokine spectrum genotyping.Keywords: ethnicity, NODAT, transplantation, immunosuppression

Published
2019

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