835 results on '"Geyer, Matthias"'
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2. Role of ZFHX4 in orofacial clefting based on human genetic data and zebrafish models
3. Insights into reproduction-regulating NOD-like receptors
4. Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
5. Structural basis of Cdk7 activation by dual T-loop phosphorylation
6. Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies
7. Maxwell's equations revisited -- mental imagery and mathematical symbols
8. Cryo-EM structure of the human native plasma coagulation factor XIII complex
9. Transnationale Geschichte.: Die französische Hochschul- und Forschungspolitik zwischen globalem Anspruch und nationaler Umsetzung (2002 bis 2012)
10. Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation.
11. Actin associates with actively elongating genes and binds directly to the Cdk9 subunit of P-TEFb
12. Effective Hamiltonian model for helically constrained quantum systems within adiabatic perturbation theory: application to the Chirality-Induced Spin Selectivity (CISS) Effect
13. Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
14. The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation
15. Antiviral signalling by a cyclic nucleotide activated CRISPR protease
16. Transnationale Geschichte.: Transnationale Vergleichspraktiken der deutschen und der US-amerikanischen Eisen- und Stahlindustrie (1870–1940)
17. Structural aspects of inflammasomes forming NOD-like receptors
18. Contributors
19. Alternative splicing regulates stochastic NLRP3 activity.
20. Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain
21. Comparative transcriptional profiling of regenerating damaged knee joints in two animal models of the newt Notophthalmus viridescens strengthens the role of candidate genes involved in osteoarthritis
22. A nonsense variant in KRT31 is associated with autosomal dominant monilethrix.
23. Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3
24. Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus
25. Deficiency in coatomer complex I causes aberrant activation of STING signalling
26. ATP-binding and hydrolysis of human NLRP3
27. Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter
28. Rezension von: Geyer, Matthias; Nitsch, Edgar; Simon, Theo, Geologie von Baden-Württemberg
29. The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease
30. LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding
31. Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma
32. Global mapping of Salmonella enterica-host protein-protein interactions during infection
33. NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity
34. 1,6-Hexanediol, commonly used to dissolve liquid–liquid phase separated condensates, directly impairs kinase and phosphatase activities
35. A Surface Plasmon Resonance-Based Strategy to Characterize Interactions of NLR Proteins with Associated Factors
36. An Assay for the Seeding of Homotypic Pyrin Domain Filament Transitions
37. Discovery and resistance mechanism of a selective CDK12 degrader
38. The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease.
39. CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells
40. β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
41. The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening
42. Data from Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma
43. Supplementary Figure4 from Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma
44. Structural basis of Cdk7 activation by dual T-loop phosphorylation
45. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates
46. Rational discovery of molecular glue degraders via scalable chemical profiling
47. Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation
48. MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation
49. P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress
50. Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations
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