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8 results on '"Geukes, Simon H."'

3. Methodological Recommendations for Studies on the Daily Life Implementation of Implantable Communication-Brain–Computer Interfaces for Individuals With Locked-in Syndrome

Author

Vansteensel, Mariska J., primary, Branco, Mariana P., additional, Leinders, Sacha, additional, Freudenburg, Zac F., additional, Schippers, Anouck, additional, Geukes, Simon H., additional, Gaytant, Michael A., additional, Gosselaar, Peter H., additional, Aarnoutse, Erik J., additional, and Ramsey, Nick F., additional

Published
2022
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4. Methodological Recommendations for Studies on the Daily Life Implementation of Implantable Communication-Brain–Computer Interfaces for Individuals With Locked-in Syndrome

Author

Projectafdeling functional imaging, Brain, Longziekten, Other research (not in main researchprogram), Neurochirurgen, Vansteensel, Mariska J., Branco, Mariana P., Leinders, Sacha, Freudenburg, Zac F., Schippers, Anouck, Geukes, Simon H., Gaytant, Michael A., Gosselaar, Peter H., Aarnoutse, Erik J., Ramsey, Nick F., Projectafdeling functional imaging, Brain, Longziekten, Other research (not in main researchprogram), Neurochirurgen, Vansteensel, Mariska J., Branco, Mariana P., Leinders, Sacha, Freudenburg, Zac F., Schippers, Anouck, Geukes, Simon H., Gaytant, Michael A., Gosselaar, Peter H., Aarnoutse, Erik J., and Ramsey, Nick F.

Published
2022

6. High-frequency band temporal dynamics in response to a grasp force task

Author

Projectafdeling functional imaging, Brain, Branco, Mariana P., Geukes, Simon H., Aarnoutse, Erik J., Vansteensel, Mariska J., Freudenburg, Zachary V., Ramsey, Nick F., Projectafdeling functional imaging, Brain, Branco, Mariana P., Geukes, Simon H., Aarnoutse, Erik J., Vansteensel, Mariska J., Freudenburg, Zachary V., and Ramsey, Nick F.

Published
2019

8. Longevity of a Brain-Computer Interface for Amyotrophic Lateral Sclerosis.

Author

Vansteensel, Mariska J., Leinders, Sacha, Branco, Mariana P., Crone, Nathan E., Denison, Timothy, Freudenburg, Zachary V., Geukes, Simon H., and Ramsey, Nick F.

Subjects
*AMYOTROPHIC lateral sclerosis, *BRAIN-computer interfaces, *TOMOGRAPHY, *NEURODEGENERATION, *LONGEVITY, *ARTIFICIAL implants, *COMMUNICATIVE disorders
Abstract

The durability of communication with the use of brain-computer interfaces in persons with progressive neurodegenerative disease has not been extensively examined. We report on 7 years of independent at-home use of an implanted brain-computer interface for communication by a person with advanced amyotrophic lateral sclerosis (ALS), the inception of which was reported in 2016. The frequency of at-home use increased over time to compensate for gradual loss of control of an eye-gaze-tracking device, followed by a progressive decrease in use starting 6 years after implantation. At-home use ended when control of the brain-computer interface became unreliable. No signs of technical malfunction were found. Instead, the amplitude of neural signals declined, and computed tomographic imaging revealed progressive atrophy, which suggested that ALS-related neurodegeneration ultimately rendered the brain-computer interface ineffective after years of successful use, although alternative explanations are plausible. (Funded by the National Institute on Deafness and Other Communication Disorders and others; ClinicalTrials.gov number, NCT02224469). [ABSTRACT FROM AUTHOR]

Published
2024
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