195 results on '"Gerstmeier, Jana"'
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2. Lipid droplets control mitogenic lipid mediator production in human cancer cells
3. Sex hormone deprivation abolishes sex‐specific differences in murine colon inflammation and related lipid mediator production.
4. Introduction of Unit-Dose Care in the 1,125 Bed Teaching Hospital: Practical Experience and Time Saving on Wards
5. We Ask and Listen: A Group-Wide Retrospective Survey on Satisfaction with Digital Medication Software
6. Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis
7. Incidence and severity of G6PI-induced arthritis are not increased in genetically distinct mouse strains upon aging
8. Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products
9. Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase
10. Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution
11. Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation
12. Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7
13. Synthesis and biological evaluation of C(5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7
14. 4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)
15. Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution.
16. Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
17. Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation
18. Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males
19. Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation
20. Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation.
21. Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP)
22. Plectranthus Zeylanicus: A Rich Source of Secondary Metabolites with Antimicrobial, Disinfectant and Anti-Inflammatory Activities
23. Staphylococcus aureus controls eicosanoid and specialized pro‐resolving mediator production via lipoteichoic acid
24. Lipid droplets control mitogenic lipid mediator production in human cancer cells
25. Controlled Release of the α-Tocopherol-Derived Metabolite α-13′-Carboxychromanol from Bacterial Nanocellulose Wound Cover Improves Wound Healing
26. Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation
27. Stereoselective total synthesis of parthenolides indicates target selectivity for tubulin carboxypeptidase activity† †Electronic supplementary information (ESI) available: Syntheses of starting materials. Experimental procedures, analytical data for all new compounds. Cell and macrophage experiment methods and data. NMR based structure elucidation of compound 16f (PDF). X-ray of compound (±)-9 (CIF). CCDC 1902988. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c9sc01473j
28. Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators
29. Chromatographic separation and biological evaluation of benzimidazole derivative enantiomers as inhibitors of leukotriene biosynthesis
30. Modified Bacterial Cellulose Dressings to Treat Inflammatory Wounds
31. Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
32. Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes
33. The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka
34. Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase
35. EVOLUTION OF SELECTIVE FLAP INHIBITOR BRP-7 INTO MULTI-TARGET INHIBITOR OF FLAP, 5-LO AND MPGES-1 IN THE ARACHIDONIC ACID PATHWAY
36. ANTİLÖKOTRİEN ETKİLİ 1,2,5-TRİSÜBSTİTÜEBENZİMİDAZOL TÜREVLERİNİN GELİŞTİRİLMESİ ÜZERİNDE YAPILAN ÇALIŞMALAR
37. Discovery and Development of Novel Anti-cancer and Anti-inflammatory Compounds: Medicinal Chemistry Challenges
38. Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation
39. Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis
40. Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy
41. A 5‑lipoxygenase-specific sequence motif impedes enzyme activity and confers dependence on a partner protein
42. Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome
43. Discovery of Novel 5-Lipoxygenase Activating Protein (FLAP) Inhibitors by Virtual Screening
44. Developing Multi-target Inhibitors of Arachidonic Acid Pathway Based on the FLAP Inhibitor BRP-7
45. Lipophilic extracts of Leucas zeylanica, a multi-purpose medicinal plant in the tropics, inhibit key enzymes involved in inflammation and gout
46. Discovery of Novel 5-Lipoxygenase Activating Protein (FLAP) Inhibitors by Combined Ligand- and Structure-Based Virtual Screening
47. Bioisosteric Tuning of FLAP Inhibitor BRP-7 Towards a More Potent Antiinmlammatory Agent with Multiligand Inhibitor Properties in the Arachidonic Acid (AA) Pathway
48. Novel BRP 7 Derivatives Targeting FLAP Potent Inhibitors of Leukotriene Biosynthesis
49. Discovery of 4 5 Diarylisoxazol 3 Carboxylic Acid Skeleton as a Novel Chemotype for Inhibition of 5 Lipoxygenase Activating Proteın FLAP
50. Exploratıon of the Chemıcal Space Around C 5 Posıtıon Of The Benzimidazole Nucleus in BRP 7 Towards More Potent Inhıbıtors of Human 5 Lıpoxygenase Actıvatıng Proteın FLAP
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