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317 results on '"Germonpré, Mietje"'

2. Grey wolf genomic history reveals a dual ancestry of dogs

Author

Bergström, Anders, Stanton, David WG, Taron, Ulrike H, Frantz, Laurent, Sinding, Mikkel-Holger S, Ersmark, Erik, Pfrengle, Saskia, Cassatt-Johnstone, Molly, Lebrasseur, Ophélie, Girdland-Flink, Linus, Fernandes, Daniel M, Ollivier, Morgane, Speidel, Leo, Gopalakrishnan, Shyam, Westbury, Michael V, Ramos-Madrigal, Jazmin, Feuerborn, Tatiana R, Reiter, Ella, Gretzinger, Joscha, Münzel, Susanne C, Swali, Pooja, Conard, Nicholas J, Carøe, Christian, Haile, James, Linderholm, Anna, Androsov, Semyon, Barnes, Ian, Baumann, Chris, Benecke, Norbert, Bocherens, Hervé, Brace, Selina, Carden, Ruth F, Drucker, Dorothée G, Fedorov, Sergey, Gasparik, Mihály, Germonpré, Mietje, Grigoriev, Semyon, Groves, Pam, Hertwig, Stefan T, Ivanova, Varvara V, Janssens, Luc, Jennings, Richard P, Kasparov, Aleksei K, Kirillova, Irina V, Kurmaniyazov, Islam, Kuzmin, Yaroslav V, Kosintsev, Pavel A, Lázničková-Galetová, Martina, Leduc, Charlotte, Nikolskiy, Pavel, Nussbaumer, Marc, O’Drisceoil, Cóilín, Orlando, Ludovic, Outram, Alan, Pavlova, Elena Y, Perri, Angela R, Pilot, Małgorzata, Pitulko, Vladimir V, Plotnikov, Valerii V, Protopopov, Albert V, Rehazek, André, Sablin, Mikhail, Seguin-Orlando, Andaine, Storå, Jan, Verjux, Christian, Zaibert, Victor F, Zazula, Grant, Crombé, Philippe, Hansen, Anders J, Willerslev, Eske, Leonard, Jennifer A, Götherström, Anders, Pinhasi, Ron, Schuenemann, Verena J, Hofreiter, Michael, Gilbert, M Thomas P, Shapiro, Beth, Larson, Greger, Krause, Johannes, Dalén, Love, and Skoglund, Pontus

Subjects
Africa, Animals, DNA, Ancient, Dogs, Domestication, Europe, Genome, Genomics, History, Ancient, Middle East, Mutation, North America, Phylogeny, Selection, Genetic, Siberia, Tumor Suppressor Proteins, Wolves, General Science & Technology
Abstract

The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canis familiaris) lived1-8. Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT88 40,000-30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, we also found that dogs in the Near East and Africa derive up to half of their ancestry from a distinct population related to modern southwest Eurasian wolves, reflecting either an independent domestication process or admixture from local wolves. None of the analysed ancient wolf genomes is a direct match for either of these dog ancestries, meaning that the exact progenitor populations remain to be located.

Published
2022

3. Natural and human-driven selection of a single non-coding body size variant in ancient and modern canids

Author

Plassais, Jocelyn, vonHoldt, Bridgett M, Parker, Heidi G, Carmagnini, Alberto, Dubos, Nicolas, Papa, Ilenia, Bevant, Kevin, Derrien, Thomas, Hennelly, Lauren M, Whitaker, D Thad, Harris, Alex C, Hogan, Andrew N, Huson, Heather J, Zaibert, Victor F, Linderholm, Anna, Haile, James, Fest, Thierry, Habib, Bilal, Sacks, Benjamin N, Benecke, Norbert, Outram, Alan K, Sablin, Mikhail V, Germonpré, Mietje, Larson, Greger, Frantz, Laurent, and Ostrander, Elaine A

Subjects
Biological Sciences, Genetics, Alleles, Animals, Body Size, Breeding, Canidae, Humans, Wolves, IGF1, ancient DNA, antisense lncRNA, body size, canid evolution, canine, dog, domestication, long non-coding RNA, wolf, Medical and Health Sciences, Psychology and Cognitive Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Psychology
Abstract

Domestic dogs (Canis lupus familiaris) are the most variable-sized mammalian species on Earth, displaying a 40-fold size difference between breeds.1 Although dogs of variable size are found in the archeological record,2-4 the most dramatic shifts in body size are the result of selection over the last two centuries, as dog breeders selected and propagated phenotypic extremes within closed breeding populations.5 Analyses of over 200 domestic breeds have identified approximately 20 body size genes regulating insulin processing, fatty acid metabolism, TGFβ signaling, and skeletal formation.6-10 Of these, insulin-like growth factor 1 (IGF1) predominates, controlling approximately 15% of body size variation between breeds.8 The identification of a functional mutation associated with IGF1 has thus far proven elusive.6,10,11 Here, to identify and elucidate the role of an ancestral IGF1 allele in the propagation of modern canids, we analyzed 1,431 genome sequences from 13 species, including both ancient and modern canids, thus allowing us to define the evolutionary history of both ancestral and derived alleles at this locus. We identified a single variant in an antisense long non-coding RNA (IGF1-AS) that interacts with the IGF1 gene, creating a duplex. While the derived mutation predominates in both modern gray wolves and large domestic breeds, the ancestral allele, which predisposes to small size, was common in small-sized breeds and smaller wild canids. Our analyses demonstrate that this major regulator of canid body size nearly vanished in Pleistocene wolves, before its recent resurgence resulting from human-imposed selection for small-sized breed dogs.

Published
2022

5. The origins and spread of domestic horses from the Western Eurasian steppes

Author

Librado, Pablo, Khan, Naveed, Fages, Antoine, Kusliy, Mariya A, Suchan, Tomasz, Tonasso-Calvière, Laure, Schiavinato, Stéphanie, Alioglu, Duha, Fromentier, Aurore, Perdereau, Aude, Aury, Jean-Marc, Gaunitz, Charleen, Chauvey, Lorelei, Seguin-Orlando, Andaine, Der Sarkissian, Clio, Southon, John, Shapiro, Beth, Tishkin, Alexey A, Kovalev, Alexey A, Alquraishi, Saleh, Alfarhan, Ahmed H, Al-Rasheid, Khaled AS, Seregély, Timo, Klassen, Lutz, Iversen, Rune, Bignon-Lau, Olivier, Bodu, Pierre, Olive, Monique, Castel, Jean-Christophe, Boudadi-Maligne, Myriam, Alvarez, Nadir, Germonpré, Mietje, Moskal-del Hoyo, Magdalena, Wilczyński, Jarosław, Pospuła, Sylwia, Lasota-Kuś, Anna, Tunia, Krzysztof, Nowak, Marek, Rannamäe, Eve, Saarma, Urmas, Boeskorov, Gennady, Lōugas, Lembi, Kyselý, René, Peške, Lubomír, Bălășescu, Adrian, Dumitrașcu, Valentin, Dobrescu, Roxana, Gerber, Daniel, Kiss, Viktória, Szécsényi-Nagy, Anna, Mende, Balázs G, Gallina, Zsolt, Somogyi, Krisztina, Kulcsár, Gabriella, Gál, Erika, Bendrey, Robin, Allentoft, Morten E, Sirbu, Ghenadie, Dergachev, Valentin, Shephard, Henry, Tomadini, Noémie, Grouard, Sandrine, Kasparov, Aleksei, Basilyan, Alexander E, Anisimov, Mikhail A, Nikolskiy, Pavel A, Pavlova, Elena Y, Pitulko, Vladimir, Brem, Gottfried, Wallner, Barbara, Schwall, Christoph, Keller, Marcel, Kitagawa, Keiko, Bessudnov, Alexander N, Bessudnov, Alexander, Taylor, William, Magail, Jérome, Gantulga, Jamiyan-Ombo, Bayarsaikhan, Jamsranjav, Erdenebaatar, Diimaajav, Tabaldiev, Kubatbeek, Mijiddorj, Enkhbayar, Boldgiv, Bazartseren, Tsagaan, Turbat, Pruvost, Mélanie, Olsen, Sandra, Makarewicz, Cheryl A, Valenzuela Lamas, Silvia, Albizuri Canadell, Silvia, Nieto Espinet, Ariadna, Iborra, Ma Pilar, Lira Garrido, Jaime, Rodríguez González, Esther, Celestino, Sebastián, Olària, Carmen, Arsuaga, Juan Luis, Kotova, Nadiia, Pryor, Alexander, Crabtree, Pam, and Zhumatayev, Rinat

Subjects
Animals, Archaeology, Asia, DNA, Ancient, Domestication, Europe, Genetics, Population, Genome, Grassland, Horses, Phylogeny, General Science & Technology
Abstract

Domestication of horses fundamentally transformed long-range mobility and warfare1. However, modern domesticated breeds do not descend from the earliest domestic horse lineage associated with archaeological evidence of bridling, milking and corralling2-4 at Botai, Central Asia around 3500 BC3. Other longstanding candidate regions for horse domestication, such as Iberia5 and Anatolia6, have also recently been challenged. Thus, the genetic, geographic and temporal origins of modern domestic horses have remained unknown. Here we pinpoint the Western Eurasian steppes, especially the lower Volga-Don region, as the homeland of modern domestic horses. Furthermore, we map the population changes accompanying domestication from 273 ancient horse genomes. This reveals that modern domestic horses ultimately replaced almost all other local populations as they expanded rapidly across Eurasia from about 2000 BC, synchronously with equestrian material culture, including Sintashta spoke-wheeled chariots. We find that equestrianism involved strong selection for critical locomotor and behavioural adaptations at the GSDMC and ZFPM1 genes. Our results reject the commonly held association7 between horseback riding and the massive expansion of Yamnaya steppe pastoralists into Europe around 3000 BC8,9 driving the spread of Indo-European languages10. This contrasts with the scenario in Asia where Indo-Iranian languages, chariots and horses spread together, following the early second millennium BC Sintashta culture11,12.

Published
2021

8. Population dynamics and demographic history of Eurasian collared lemmings

Author

Lord, Edana, Marangoni, Aurelio, Baca, Mateusz, Popović, Danijela, Goropashnaya, Anna V., Stewart, John R., Knul, Monika V., Noiret, Pierre, Germonpré, Mietje, Jimenez, Elodie-Laure, Abramson, Natalia I., Vartanyan, Sergey, Prost, Stefan, Smirnov, Nickolay G., Kuzmina, Elena A., Olsen, Remi-André, Fedorov, Vadim B., and Dalén, Love

Published
2022
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14. The evolutionary and phylogeographic history of woolly mammoths: a comprehensive mitogenomic analysis.

Author

Chang, Dan, Knapp, Michael, Enk, Jacob, Lippold, Sebastian, Kircher, Martin, Lister, Adrian, MacPhee, Ross DE, Widga, Christopher, Czechowski, Paul, Sommer, Robert, Hodges, Emily, Stümpel, Nikolaus, Barnes, Ian, Dalén, Love, Derevianko, Anatoly, Germonpré, Mietje, Hillebrand-Voiculescu, Alexandra, Constantin, Silviu, Kuznetsova, Tatyana, Mol, Dick, Rathgeber, Thomas, Rosendahl, Wilfried, Tikhonov, Alexey N, Willerslev, Eske, Hannon, Greg, Lalueza-Fox, Carles, Joger, Ulrich, Poinar, Hendrik, Hofreiter, Michael, and Shapiro, Beth

Subjects
Animals, DNA, Mitochondrial, Sequence Analysis, DNA, Phylogeny, Fossils, North America, Asia, Europe, Female, Male, Gene Flow, Extinction, Biological, Genome, Mitochondrial, Mammoths, Biological Evolution, Phylogeography, Animal Distribution, Genetics, DNA, Mitochondrial, Sequence Analysis, Extinction, Biological, Genome, Biochemistry and Cell Biology, Other Physical Sciences
Abstract

Near the end of the Pleistocene epoch, populations of the woolly mammoth (Mammuthus primigenius) were distributed across parts of three continents, from western Europe and northern Asia through Beringia to the Atlantic seaboard of North America. Nonetheless, questions about the connectivity and temporal continuity of mammoth populations and species remain unanswered. We use a combination of targeted enrichment and high-throughput sequencing to assemble and interpret a data set of 143 mammoth mitochondrial genomes, sampled from fossils recovered from across their Holarctic range. Our dataset includes 54 previously unpublished mitochondrial genomes and significantly increases the coverage of the Eurasian range of the species. The resulting global phylogeny confirms that the Late Pleistocene mammoth population comprised three distinct mitochondrial lineages that began to diverge ~1.0-2.0 million years ago (Ma). We also find that mammoth mitochondrial lineages were strongly geographically partitioned throughout the Pleistocene. In combination, our genetic results and the pattern of morphological variation in time and space suggest that male-mediated gene flow, rather than large-scale dispersals, was important in the Pleistocene evolutionary history of mammoths.

Published
2017

24. Geometric morphometric assessment of the fossil bears of Namur, Belgium: Allometry and ecomorphology.

Author

van Heteren, Anneke H. and Germonpré, Mietje

Subjects
*BROWN bear, *PRINCIPAL components analysis, *ONTOGENY, *FOSSILS, *ALLOMETRY, *CAVES, *FOSSIL plants
Abstract

The Namur area in Belgium is useful to study brown (Ursus arctos) and cave bears (Ursus spelaeus) as the assemblage contains little temporal and no geographical variation. Here, we aim to assess ontogenetic allometry within cave bears, as well as ecomorphological differences between adult brown bears (n = 9), adult cave bears (n = 5) and juvenile cave bears (n = 3). Landmarks for 3D digitization of the mandible were chosen based on the taphonomical damage of the specimens. Extant brown bears and extinct Pleistocene brown and cave bears were digitized with a Microscribe G2. Generalized Procrustes superimposition was performed on the coordinates. Allometry was studied using regression analysis. Principal component analysis (PCA) was conducted to assess ecomorphological differences between the groups. 61% of the shape variance within juvenile and adult cave bears was predicted by size (n = 8, p < 0.01). The juvenile cave bears have relatively deep horizontal rami. In adult cave bears, the horizontal ramus is much narrower dorsoventrally. Juvenile cave bears have a small masseteric fossa and a short coronoid process, whereas both are larger, relative to mandible size, in adult cave bears. This made juvenile cave bears likely less effective masticators than fully grown cave bears. In the PCA, principal component (PC) 1 accounts for 45.0% of the total variance and PC2 accounts for 27.6%. Fossil U. arctos from Namur fall within the 95% confidence interval of modern North American U. arctos on both PCs, but are more similar to cave bears than the average extant brown bear. From the similarity of fossil and modern brown bears, it can be deduced that the diet of fossil brown bears was probably also within the range of their modern North American conspecifics, although they might have been more efficient at masticating plant matter. [ABSTRACT FROM AUTHOR]

Published
2023
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25. Les sciences archéologiques à l’ère du virtuel

Author

Bassel, Léna, Bauer, Catherine Claudia, Bédécarrats, Samuel, Boulbes, Nicolas, Bousquet, Bruno, Boussard, Matthieu, Burlet, Christian, Camus, Hubert, Carrez, Philippe, Celiberti, Vincenzo, Chapoulie, Rémy, Chevalier, Tony, Chopinaud, Caroline, Colombo, Antony, Comte, Florent, Coqueugniot, Hélène, Cordonnier, Guillaume, Coutinho-Nogueira, Dany, Deguilloux, Marie-France, Delaby, Serge, Deldique, Damien, Dutailly, Bruno, Dutour, Olivier, Ferrier, Catherine, Feruglio, Valérie, Fontaneil, Cédric, Gaultier, Matthieu, Genty, Dominique, Germonpré, Mietje, Grégoire, Sophie, Harfouche, Antoine, Hervé, Thierry, Jaubert, Jacques, Konik, Stéphane, Kurdy, Micheline, Lacanette, Delphine, Lartigot-Campin, Anne-Sophie, Lázničková-Galetová, Martina, Leblanc, Jean Claude, Ledoux, Lysianna, Lévêque, François, Maksud, Frédéric, Moigne, Anne-Marie, Mora, Pascal, Muth, Xavier, Paillet, Patrick, Perrenoud, Christian, Pois, Véronique, Pruvost, Mélanie, Quinio, Bernard, Rittemard, Charlotte, Rouzaud, François, Rouzaud, Jean-Noël, Sachau-Carcel, Géraldine, Sagory, Thomas, Saint-Pierre, Christophe, Santos, Frédéric, Saos, Thibaud, Soulier, Denise, Soulier, Michel, Testu, Agnès, Tillier, Anne-Marie, Travers, Nadine, Van Noten, Koen, Verheyden, Sophie, Coqueugniot, Hélène, Dutour, Olivier, Jaubert, Jacques, and Paillet, Patrick

Subjects
Moyen Âge, époque contemporaine, archéologie, Préhistoire, Communication, culture numérique, GTC, Antiquité, anthropologie, LAN004000, Archaeology, sciences de l’information et de la communication, humanités numériques, époque moderne
Abstract

Grâce à la « révolution numérique », les chercheurs ont désormais accès à de nouveaux outils d’exploration qui ont considérablement renouvelé les pratiques scientifiques traditionnelles. L’archéologie a pleinement intégré cette ère du virtuel. Ce recueil explore les applications des techniques de l’imagerie numérique, comme la photogrammétrie, le scanner laser, la microtomodentométrie, la modélisation tridimensionnelle et les systèmes d’information 3D, ou la réalité virtuelle et augmentée. L’introduction de l’imagerie numérique a également changé la diffusion des connaissances archéologiques et fait évoluer la muséographie. Les travaux présentés concernent des vestiges ostéoarchéologiques humains et animaux, des sites paléolithiques et des grottes ornées, ainsi que des sites proche-orientaux mis en danger par les conflits actuels. Le Congrès national des sociétés historiques et scientifiques rassemble chaque année universitaires, membres de sociétés savantes et jeunes chercheurs. Ce recueil est issu de travaux présentés lors du 144e Congrès sur le thème « Le réel et le virtuel ».

Published
2023

26. Évidence de manipulation humaine des os de Canidae dans les sites gravettiens (Dolní Věstonice I et Předmostí I, Moravie, République tchèque)

Author

Lázničková-Galetová, Martina, Germonpré, Mietje, and Bauer, Catherine Claudia

Subjects
Gravettien, Moyen Âge, époque contemporaine, archéologie, Préhistoire, Communication, culture numérique, Canids, manipulation humaine, GTC, Antiquité, Gravettian, anthropologie, LAN004000, human manipulation, sciences de l’information et de la communication, humanités numériques, époque moderne, Canidae
Abstract

Le matériel des sites gravettiens de Moravie (Dolní Věstonice I et Předmostí I), où la domestication du loup / chien a été étudiée, a été analysé afin de détecter la présence éventuelle d’interventions ou manipulations effectuées par l’Homme, en l’occurrence des artefacts incrustés à l’intérieur des crânes de Canidae ou des crânes portanidaent des perforations post mortem. Nous avons utilisé les méthodes de segmentation et l’analyse de CT-scans pour visualiser les structures internes et pour caractériser les perforations. Grâce à nos résultats, nous pouvons apporter des éléments de réponse sur la relation des Hommes modernes et des grands Canidae, potentiellement domestiqués avant le Dernier Maximum glaciaire. Material from Gravettian sites in Moravia (Dolní Věstonice I and Předmostí I), where the domestication of wolf / dog has been studied, was analysed in order to detect the existence of potential interventions or manipulations by humans, in this case artefacts inserted into skulls of Canids or post mortem perforations of skulls. Segmentation methods and analyses of CT scans were applied to visualise internal structures and to study the perforations. The obtained results allow to partially answer the questions concerning the relationship between Modern Humans and large Canids potentially domesticated before the Last Glacial Maximum.

Published
2023

28. Major excursions in sulfur isotopes linked to permafrost change in Eurasia during the last 50,000 Years.

Author

Stevens, Rhiannon, primary, Reade, Hazel, additional, Sayle, Kerry, additional, Tripp, Jennifer, additional, Frémondeau, Delphine, additional, Lister, Adrian, additional, Barnes, Ian, additional, Germonpré, Mietje, additional, Street, Martin, additional, Murton, Julian, additional, Bottrell, Simon, additional, and Higham, Thomas, additional

Published
2023
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36. Mitochondrial DNA diversity and evolution of the Pleistocene cave bear complex

Author

Stiller, Mathias, Molak, Martyna, Prost, Stefan, Rabeder, Gernot, Baryshnikov, Gennady, Rosendahl, Wilfried, Münzel, Susanne, Bocherens, Hervé, Grandal-d'Anglade, Aurora, Hilpert, Brigitte, Germonpré, Mietje, Stasyk, Oleh, Pinhasi, Ron, Tintori, Andrea, Rohland, Nadin, Mohandesan, Elmira, Ho, Simon Y.W., Hofreiter, Michael, and Knapp, Michael

Published
2014
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41. Additional file 2 of Population dynamics and demographic history of Eurasian collared lemmings

Author

Lord, Edana, Marangoni, Aurelio, Baca, Mateusz, Popović, Danijela, Goropashnaya, Anna V., Stewart, John R., Knul, Monika V., Noiret, Pierre, Germonpré, Mietje, Jimenez, Elodie-Laure, Abramson, Natalia I., Vartanyan, Sergey, Prost, Stefan, Smirnov, Nickolay G., Kuzmina, Elena A., Olsen, Remi-André, Fedorov, Vadim B., and Dalén, Love

Abstract

Additional file 2: Supplementary materials and methods. Information regarding supplemental methods. Figure S1. PSMC plot for Dicrostonyx torquatus using three different mutation rates estimated for mouse (Mus musculus).

Published
2022
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46. Intraspecific Phylogenetic Analysis of Siberian Woolly Mammoths Using Complete Mitochondrial Genomes

Author

Gilbert, M. Thomas P., Drautz, Daniela I., Lesk, Arthur M., Ho, Simon Y. W., Qi, Ji, Ratan, Aakrosh, Hsu, Chih-Hao, Sher, Andrei, Dalén, Love, Götherström, Anders, Tomsho, Lynn P., Rendulic, Snjezana, Packard, Michael, Campos, Paula F., Kuznetsova, Tatyana V., Shidlovskiy, Fyodor, Tikhonov, Alexei, Willerslev, Eske, Iacumin, Paola, Buigues, Bernard, Ericson, Per G. P., Germonpré, Mietje, Kosintsev, Pavel, Nikolaev, Vladimir, Nowak-Kemp, Malgosia, Knight, James R., Irzyk, Gerard P., Perbost, Clotilde S., Fredrikson, Karin M., Harkins, Timothy T., Sheridan, Sharon, Miller, Webb, and Schuster, Stephan C.

Published
2008
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49. Whole-Genome Shotgun Sequencing of Mitochondria from Ancient Hair Shafts

Author

Gilbert, M. Thomas P., Tomsho, Lynn P., Rendulic, Snjezana, Packard, Michael, Drautz, Daniela I., Sher, Andrei, Tikhonov, Alexei, Dalén, Love, Kuznetsova, Tatyana, Kosintsev, Pavel, Campos, Paula F., Higham, Thomas, Collins, Matthew J., Wilson, Andrew S., Shidlovskiy, Fyodor, Buigues, Bernard, Ericson, Per G. P., Germonpré, Mietje, Götherström, Anders, Iacumin, Paola, Nikolaev, Vladimir, Nowak-Kemp, Malgosia, Willerslev, Eske, Knight, James R., Irzyk, Gerard P., Perbost, Clotilde S., Fredrikson, Karin M., Harkins, Timothy T., Sheridan, Sharon, Miller, Webb, and Schuster, Stephan C.

Published
2007
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