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114 results on '"Germanà, Bastianello"'

1. Upper endoscopy in elderly patients: a multicentre, cross-sectional study

Author

Zullo, Angelo, De Francesco, Vincenzo, Amato, Arnaldo, Bergna, Irene, Bendia, Emanuele, Giorgini, Giorgia, Buscarini, Elisabetta, Manfredi, Guido, Cadoni, Sergio, Cannizzaro, Renato, Realdon, Stefano, Ciuffi, Mario, Ignomirelli, Orazio, Da Massa Carrara, Paola, Finucci, Giovanni, Di Somma, Antonietta, Frandina, Chiara, Loria, Mariafrancesca, Galeazzi, Francesca, Ferrara, Francesco, Gemme, Carlo, Bertetti, Noemi Sara, Gentili, Federica, Lotito, Antonio, Germanà, Bastianello, Russo, Nunzia, Grande, Giuseppe, Conigliaro, Rita, Cravero, Federico, Venezia, Giovanna, Marmo, Riccardo, Senneca, Piera, Milano, Angelo, Efthymakis, Konstantinos, Monica, Fabio, Montalto, Paolo, Lombardi, Mario, Morelli, Olivia, Castellani, Danilo, Nigro, Daniela, Festa, Roberto, Peralta, Sergio, Grasso, Maria, Privitera, Antonello, Di Stefano, Maria Emanuela, Scaccianoce, Giuseppe, Loiacono, Mariangela, Segato, Sergio, Balzarini, Marco, Satta, Paolo Usai, Lai, Mariantonia, Fortunato, Francesca, and Manta, Raffaele

Published
2024
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2. Correction to: Upper endoscopy in elderly patients: A multicentre, cross‑sectional study

Author

Zullo, Angelo, De Francesco, Vincenzo, Amato, Arnaldo, Bergna, Irene, Bendia, Emanuele, Giorgini, Giorgia, Buscarini, Elisabetta, Manfredi, Guido, Cadoni, Sergio, Cannizzaro, Renato, Realdon, Stefano, Ciuffi, Mario, Ignomirelli, Orazio, Da Massa Carrara, Paola, Finucci, Giovanni, Di Somma, Antonietta, Frandina, Chiara, Loria, Mariafrancesca, Galeazzi, Francesca, Ferrara, Francesco, Gemme, Carlo, Bertetti, Noemi Sara, Gentili, Federica, Lotito, Antonio, Germanà, Bastianello, Russo, Nunzia, Grande, Giuseppe, Conigliaro, Rita, Cravero, Federico, Venezia, Giovanna, Marmo, Riccardo, Senneca, Piera, Milano, Angelo, Efthymakis, Konstantinos, Monica, Fabio, Montalto, Paolo, Lombardi, Mario, Morelli, Olivia, Castellani, Danilo, Nigro, Daniela, Festa, Roberto, Peralta, Sergio, Grasso, Maria, Privitera, Antonello, Di Stefano, Maria Emanuela, Scaccianoce, Giuseppe, Loiacono, Mariangela, Segato, Sergio, Balzarini, Marco, Satta, Paolo Usai, Lai, Mariantonia, Fortunato, Francesca, and Manta, Raffaele

Published
2024
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3. Low Colorectal Cancer Risk After Resection of High-Risk Pedunculated Polyps

Author

Zorzi, Manuel, Battagello, Jessica, Amidei, Claudio Barbiellini, Antonelli, Giulio, Germanà, Bastianello, Valiante, Flavio, Benvenuti, Stefano, Tringali, Alberto, Bortoluzzi, Francesco, Cervellin, Erica, Giacomin, Davide, Meggiato, Tamara, Rizzotto, Erik Rosa, Fregonese, Diego, Dinca, Manuela, Baldassarre, Gianluca, Scalon, Paola, Pantalena, Maurizio, Milan, Luisa, Bulighin, Gianmarco, Di Piramo, Daniele, Azzurro, Maurizio, Gabbrielli, Armando, Repici, Alessandro, Rugge, Massimo, and Hassan, Cesare

Published
2024
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4. Real-time determination of gastric juice pH with EndoFaster® for atrophic gastritis assessment

Author

Zullo, Angelo, Germanà, Bastianello, Galliani, Ermenegildo, Iori, Andrea, de Pretis, Giovanni, Manfredi, Guido, Buscarini, Elisabetta, Ciuffi, Mario, Ignomirelli, Orazio, Farinati, Fabio, Savarino, Edoardo, Pallini, Paolo, Milan, Luisa, Conigliaro, Rita, Grande, Giuseppe, Cannizzaro, Renato, Maiero, Stefania, Pisani, Antonio, Marangi, Stefania, Manta, Raffaele, Morelli, Olivia, Peralta, Sergio, La Mantia, Alessia, Buonocore, Matteo Rossano, Khalaf, Kareem, Hassan, Cesare, and Monica, Fabio

Published
2022
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5. Management of Helicobacter pylori infection: Guidelines of the Italian Society of Gastroenterology (SIGE) and the Italian Society of Digestive Endoscopy (SIED)

Author

Benedetti, Antonio, Annibale, Bruno, Burra, Patrizia, Maida, Marcello Fabio, Luzza, Francesco, Ricciardiello, Luigi, Vecchi, Maurizio, Frulloni, Luca, Repici, Alessandro, Savarino, Edoardo Vincenzo, Pasquale, Luigi, Pisani, Antonio, Lamazza, Antonietta, Cengia, Gianpaolo, Ciliberto, Enrico, Conigliaro, Rita Luisa, Da Massa Carrara, Paola, Germanà, Bastianello, Romano, Marco, Gravina, Antonietta Gerarda, Eusebi, Leonardo Henry, Pellegrino, Raffaele, Palladino, Giovanna, Frazzoni, Leonardo, Dajti, Elton, Gasbarrini, Antonio, Di Mario, Francesco, and Zagari, Rocco Maurizio

Published
2022
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6. Etrolizumab versus infliximab for the treatment of moderately to severely active ulcerative colitis (GARDENIA): a randomised, double-blind, double-dummy, phase 3 study

Author

Aboo, Nazimuddin, Ahmad, Tariq, Aldeguer Mante, Xavier, Allez, Matthieu, Almer, Sven, Altwegg, Romain, Andreu Garcia, Montserrat, Arasaradnam, Ramesh, Ardizzone, Sandro, Armuzzi, Alessandro, Arnott, Ian, Aumais, Guy, Avni-Biron, Irit, Barrow, Peter, Beales, Ian, Bermejo San Jose, Fernando, Bezuidenhout, Abraham, Biancone, Livia, Blaeker, Michael, Bloom, Stuart, Bokemeyer, Bernd, Bossa, Fabrizio, Bossuyt, Peter, Bouguen, Guillaume, Bouhnik, Yoram, Bouma, Gerd, Bourdages, Raymond, Bourreille, Arnaud, Boustiere, Christian, Brabec, Tomas, Brand, Stephan, Buening, Carsten, Buisson, Anthony, Cadiot, Guillaume, Calvet Calvo, Xavier, Carbonnel, Franck, Carpio, Daniel, Cheon, Jae Hee, Chiba, Naoki, Chioncel, Camelia, Cimpoeru, Nicoleta-Claudia, Clodi, Martin, Corazza, Gino Roberto, Cosintino, Rocco, Cotter, Jose, Creed, Thomas, Cummings, Fraser, Danese, Silvio, de' Angelis, Gian Luigi, De Maeyer, Marc, Desai, Milind, Desilets, Etienne, Desreumaux, Pierre, Dewit, Olivier, D'Haens, Geert, Dinter, Johanna, Dobru, Ecaterina Daniela, Douda, Tomas, Dumitrascu, Dan Lucian, Ebert, Matthias, Echarri Piudo, Ana, Elkhashab, Magdy, Eun, Chang Soo, Feagan, Brian, Fejes, Roland, Fidalgo, Catarina, Fishman, Sigal, Flourié, Bernard, Fowler, Sharyle, Fries, Walter, Fulop, Csaba, Fumery, Mathurin, G Kiss, Gyula, Gassner, Sonja, Gaya, Daniel, Germanà, Bastianello, Gheorghe, Liliana Simona, Gilletta de Saint Joseph, Cyrielle, Gionchetti, Paolo, Goldis, Adrian-Eugen, Gonçalves, Raquel, Grimaud, Jean-Charles, Gyökeres, Tibor, Hagege, Herve, Haidar, Andrei, Hartmann, Heinz, Hasselblatt, Peter, Hayee, Buhussain, Hebuterne, Xavier, Hellström, Per, Hindryckx, Pieter, Hlavova, Helena, Hoentjen, Frank, Howaldt, Stefanie, Hrdlicka, Ludek, Huh, Kyu Chan, Iborra Colomino, Maria Isabel, Ionita-Radu, Florentina, Irving, Peter, Jahnsen, Jørgen, Jang, ByungIk, Jansen, Jeroen, Jeon, Seong Woo, Jover Martinez, Rodrigo, Juillerat, Pascal, Karlén, Per, Kaser, Arthur, Keil, Radan, Kejariwal, Deepak, Keret, Dan, Khanna, Reena, Kim, Dongwoo, Kim, Duk Hwan, Kim, Hyo-Jong, Kim, Hyun-Soo, Kim, Joo Sung, Kim, Kueongok, Kim, Kyung-Jo, Kim, Sung Kook, Kim, Young-Ho, Klaus, Jochen, Kohn, Anna, Kojecky, Vladimir, Koo, Ja Seol, Kozak, Robert, Kremer, Milan, Kristof, Tunde, Kruger, Frederik, Laharie, David, Lahat-zok, Adi, Landa, Evgeny, Lee, Jonghun, Lee, Kang-Moon, Lee, Kook Lae, Lee, YooJin, Lenze, Frank, Lim, Wee Chian, Limdi, Jimmy, Lindsay, James, Lopez Serrano, Pilar, Louis, Edouard, Lueth, Stefan, Lukas, Milan, Maconi, Giovanni, Mana, Fazia, Mann, Steven, Mansfield, John, Marchi, Santino, Marino, Marco, Marshall, John, Martin Arranz, Maria Dolores, Mateescu, Radu-Bogdan, McLaughlin, John, McLaughlin, Simon, Melzer, Ehud, Mertens, Jessica, Mitrut, Paul, Molnar, Tamas, Muls, Vinciane, Munuswamy, Pushpakaran, Murray, Charles, Naftali, Timna, Naidoo, Visvakuren, Nanabhay, Yusuf, Negreanu, Lucian, Nguyen, Augustin, Ochsenkuehn, Thomas, Orlando, Ambrogio, Panaccione, Remo, Panes Diaz, Julian, Paritsky, Maya, Park, Dong Il, Park, Jihye, Pastorelli, Luca, Peck-Radosavljevic, Markus, Peerani, Farhad, Perez Gisbert, Javier, Peyrin-Biroulet, Laurent, Picon, Laurence, Pierik, Marieke, Ponich, Terry, Portela, Francisco, Prins, Maartens Jeroen, Racz, Istvan, Rahman, Khan Fareed, Reimund, Jean-Marie, Reinshagen, Max, Roblin, Xavier, Rocca, Rodolfo, Rogai, Francesca, Rogler, Gerhard, Salamon, Agnes, Salazar, Ennaliza, Sallo, Zoltan, Samuel, Sunil, Sans Cuffi, Miquel de los Santos, Savarino, Edoardo Vincenzo, Savarino, Vincenzo, Savoye, Guillaume, Schreiber, Stefan, Seicean, Andrada, Selinger, Christian, Serra, David Martins, Shim, Hang Hock, Shin, SungJae, Siegmund, Britta, Siffledeen, Jesse, Simmonds, Wayne, Smid, Jan, Sollano, Jose, Song, Geun Am, Speight, Alexander, Sporea, Ioan, Staessen, Dirk, Stancu, George, Steel, Alan, Stepek, David, Stoica, Victor, Sturm, Andreas, Szekely, Gyorgy, Tan, Teck Kiang, Taxonera Samso, Carlos, Thomson, John, Tichy, Michal, Toth, Gabor Tamas, Tulassay, Zsolt, Vangeli, Marcello, Varga, Marta, Vieira, Ana, Viennot, Stephanie, Villa, Erica, Vitek, Petr, Vogelsang, Harald, Vyhnalek, Petr, Wahab, Peter, Walldorf, Jens, Ye, Byong Duk, Ziady, Christopher, Colombel, Jean-Frederic, Gisbert, Javier P, Hayee, Bu'hussain, Reinisch, Walter, Tyrrell, Helen, Oh, Young S, Tole, Swati, Chai, Akiko, Chamberlain-James, Kirsten, and Tang, Meina Tao

Published
2022
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7. Corrigendum: Adherence to European society of gastrointestinal endoscopy quality performance measures for upper and lower gastrointestinal endoscopy: a nationwide survey from the Italian society of digestive endoscopy

Author

Zagari, Rocco Maurizio, primary, Frazzoni, Leonardo, additional, Fuccio, Lorenzo, additional, Bertani, Helga, additional, Crinò, Stefano Francesco, additional, Magarotto, Andrea, additional, Dajti, Elton, additional, Tringali, Andrea, additional, Da Massa Carrara, Paola, additional, Cengia, Gianpaolo, additional, Ciliberto, Enrico, additional, Conigliaro, Rita, additional, Germanà, Bastianello, additional, Lamazza, Antonietta, additional, Pisani, Antonio, additional, Spinzi, Giancarlo, additional, Capelli, Maurizio, additional, Bazzoli, Franco, additional, and Pasquale, Luigi, additional

Published
2024
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8. Multisocieties position paper: Microbiological surveillance on flexible endoscopes

Author

Bertoni, Costanza, Curti, Cesarina, Giacomini, Maurizio, Meledandri, Marcello, Palmieri, Dalia, Privitera, Gaetano, Raglio, Annibale, Tuvo, Benedetta, Colombo, Benedetta, Iannone, Teresa, Iori, Giorgio, Giaquinto, Antonella, Minenna, Angela, Petrocelli, Giulio, Valdinoci, Monia, Bortoluzzi, Francesco, Galeazzi, Francesca, Manta, Raffaele, Montalto, Paolo, Segato, Sergio, Soncini, Marco, Usai-Satta, Paolo, Vassallo, Roberto, Ferraiolo, Fabio, Roseto, Fabio, Bezziccheri, Milena, Fighera, Michele, Giampà, Ada, Mancini, Antonio, Marino, Caterina, Cerone, Marina Pisegna, Risitano, Tommaso, Sergio, Emmanuele, Sinopoli, Raffaele, De Caprio, Maria Teresa, Failla, Giuseppe, Agli, Luigi Lazzari, Majori, Maria, Toccaceli, Andrea, Marciano, Emanuele, Maurano, Attilio, Rodella, Luca, Cengia, Gianpaolo, Ciliberto, Enrico, Conigliaro, Rita, Germanà, Bastianello, Lamazza, Antonietta, Pisani, Antonio, Zagari, Rocco Maurizio, Spinzi, Giancarlo, Casini, Beatrice, Pan, Angelo, Guarini, Alessandra, Rivara, Cinzia, Zullo, Angelo, Monica, Fabio, Cimbro, Monica, Casarano, Salvatore, Inglese, Agostino, Vaghi, Adriano, Schiffino, Luigi, Capezzuto, Erminio, Da Massa Carrara, Paola, and Pasquale, Luigi

Published
2021
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9. Changes in digestive cancer diagnosis during the SARS-CoV-2 pandemic in Italy: A nationwide survey

Author

Massironi, Sara, Bianco, Maria Antonia, Germanà, Bastianello, Rodinò, Stefano, Anderloni, Andrea, Mussetto, Alessandro, Nipote, Bruno, Russo, Salvatore, Manta, Raffaele, Lauri, Adriano, Occhipinti, Vincenzo, Marco, Marco Di, Giovannone, Maurizio, Binda, Cecilia, Sbrancia, Monica, Paolo, Maria Carla Di, de’-Angelis, Gian Luigi, Fiori, Giancarla, Dal-Fante, Marco, Caro, Giuseppe de, Usai-Satta, Paolo, Cesarini, Monica, Piras, Enrico, Stasi, Elisa, Serio, Giovanni, Montalbano, Luigi Maria, Mirante, Vincenzo Giorgio, Burattini, Osvaldo, Attardo, Simona, Bargiggia, Stefano, Dinca, Manuele, Missale, Guido, Alvisi, Costanza, Broglia, Francesco, Ferraris, Luca, Conti-Bellocchi, Maria Cristina, Luigiano, Carmelo, Pallio, Socrate, Brunacci, Matteo, Manfrini, Carlo, Bozzi, Rosamaria, Checchin, Davide, Togliani, Thomas, D'errico, Antonietta, Bazzoli, Franco, La Bianca, Orazio, Berretti, Debora, Alvaro, Domenico, Buscarini, Elisabetta, Benedetti, Antonio, Monica, Fabio, Pasquale, Luigi, Buttitta, Francesco, Cameletti, Michela, Ferrari, Clarissa, and Ricciardiello, Luigi

Published
2021
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11. Distinguishing features between patients with acute diverticulitis and diverticular bleeding: Results from the REMAD registry

Author

Andrealli, Alida, Andriulli, Angelo, Ardizzone, Sandro, Astegiano, Marco, Bachetti, Francesco, Bartolozzi, Simona, Bargiggia, Stefano, Bassotti, Gabrio, Bianco, Maria Antonia, Binda, Gian Andrea, Biscaglia, Giuseppe, Bosani, Matteo, Bottiglieri, Maria Erminia, Cargiolli, Martina, Ciacci, Carolina, Colecchia, Antonio, Dell'Era, Alessandra, De Matthaeis, Marina, Di Ciaula, Agostino, Di Ruscio, Mirko, Dinelli, Marco, Festa, Virginia, Festi, Davide, Galliani, Ermenegildo, Germanà, Bastianello, Grassini, Mario, Guido, Ennio, Iafrate, Franco, Iovino, Paola, Iuliano, Donato, Laghi, Andrea, Latella, Giovanni, Manes, Giampiero, Marabotto, Elisa, Marchi, Santino, Mauro, Biagio, Maurano, Attilio, Moscatelli, Alessandro, Nascimbeni, Riccardo, Neri, Matteo, Occhipinti, Pietro, Parravicini, Marco, Pennazio, Marco, Peralta, Sergio, Portincasa, Piero, Radaelli, Franco, Reati, Raffaella, Redaelli, Alessandro, Rossi, Marco, Salerno, Raffale, Savarino, Vincenzo, Segato, Sergio, Severi, Carola, Scaccianoce, Giuseppe, Usai, Paolo, Valle, Valentina, Virgilio, Clara, Carabotti, Marilia, Morselli Labate, Antonio M, Cremon, Cesare, Cuomo, Rosario, Pace, Fabio, Andreozzi, Paolo, Falangone, Francesca, Barbara, Giovanni, and Annibale, Bruno

Published
2021
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13. Epidemiology, clinical features and diagnostic work-up of cystic neoplasms of the pancreas: Interim analysis of the prospective PANCY survey

Author

Pezzilli, Raffaele, Buscarini, Elisabetta, Pollini, Tommaso, Bonamini, Deborah, Marchegiani, Giovanni, Crippa, Stefano, Belfiori, Giulio, Sperti, Cosimo, Moletta, Lucia, Pozza, Gioia, De Nucci, Germana, Manes, Giampiero, Mandelli, Enzo D., Casadei, Riccardo, Ricci, Claudio, Alicante, Saverio, Vattiato, Claudia, Carrara, Silvia, Di Leo, Milena, Fabbri, Carlo, Giovanelli, Silvia, Barresi, Luca, Tacelli, Matteo, Mirante, Vincenzo G., Conigliaro, Rita, Antonini, Filippo, Macarri, Giampiero, Frulloni, Luca, De Marchi, Giulia, Sassatelli, Romano, Cecinato, Paolo, Del Vecchio Blanco, Giovanna, Galli, Andrea, Pezzullo, Angelo, Fantin, Alberto, Graffeo, Massimo, Frego, Mauro, Stillittano, Domenico, Monica, Fabio, Germanà, Bastianello, Capurso, Gabriele, Quartini, Mariano, Veneroni, Luigi, Cannizzaro, Renato, and Falconi, Massimo

Published
2020
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14. Upper Gastrointestinal Endoscopy Quality in Italy: A Nationwide Study

Author

Zullo, Angelo, primary, De Francesco, Vincenzo, primary, Amato, Arnaldo, primary, Bergna, Irene, primary, Bendia, Emanuele, primary, Giorgini, Giorgia, primary, Buscarini, Elisabetta, primary, Manfredi, Guido, primary, Cadoni, Sergio, primary, Cannizzaro, Renato, primary, Realdon, Stefano, primary, Ciuffi, Mario, primary, Ignomirelli, Orazio, primary, Da Massa Carrara, Paola, primary, Finucci, Giovanni, primary, Di Somma, Antonietta, primary, Frandina, Chiara, primary, Loria, Mariafrancesca, primary, Galeazzi, Francesca, primary, Ferrara, Francesco, primary, Gemme, Carlo, primary, Bertetti, Noemi Sara, primary, Gentili, Federica, primary, Lotito, Antonio, primary, Germanà, Bastianello, primary, Russo, Nunzia, primary, Grande, Giuseppe, primary, Conigliaro, Rita, primary, Cravero, Federico, primary, Venezia, Giovanna, primary, Marmo, Riccardo, primary, Senneca, Piera, primary, Milano, Angelo, primary, Efthymakis, Konstantinos, primary, Monica, Fabio, primary, Montalto, Paolo, primary, Lombardi, Mario, primary, Morelli, Olivia, primary, Castellani, Danilo, primary, Nigro, Daniela, primary, Festa, Roberto, primary, Peralta, Sergio, primary, Grasso, Maria, primary, Privitera, Antonello, primary, Distefano, Maria Emanuela, primary, Scaccianoce, Giuseppe, primary, Loiacono, Mariangela, primary, Segato, Sergio, primary, Balzarini, Marco, primary, Usai Satta, Paolo, primary, Lai, Mariantonia, primary, and Manta, Raffaele, primary

Published
2023
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15. Adherence to European Society of Gastrointestinal Endoscopy Quality Performance Measures for Upper and Lower Gastrointestinal Endoscopy: A Nationwide Survey From the Italian Society of Digestive Endoscopy.

Author

Zagari, Rocco Maurizio, Frazzoni, Leonardo, Fuccio, Lorenzo, Bertani, Helga, Crinò, Stefano Francesco, Magarotto, Andrea, Dajti, Elton, Tringali, Andrea, Carrara, Paola Da Massa, Cengia, Gianpaolo, Ciliberto, Enrico, Conigliaro, Rita, Germanà, Bastianello, Lamazza, Antonietta, Pisani, Antonio, Spinzi, Giancarlo, Capelli, Maurizio, Bazzoli, Franco, and Pasquale, Luigi

Published
2024
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16. Prevalence of Endoscopic and Histological Lesions at Upper Endoscopy: A Cross-Sectional, Multicentre Study in Clinical Practice

Author

De Francesco, Vincenzo, Zullo, Angelo, Amato, Arnaldo, Bergna, Irene, Bendia, Emanuele, Giorgini, Giorgia, Buscarini, Elisabetta, Manfredi, Guido, Cadoni, Sergio, Cannizzaro, Renato, Realdon, Stefano, Ciuffi, Mario, Ignomirelli, Orazio, Da Massa Carrara, Paola, Finucci, Giovanni, Di Somma, Antonietta, Frandina, Chiara, Loria, Mariafrancesca, Galeazzi, Francesca, Ferrara, Francesco, Gemme, Carlo, Bertetti, Noemi Sara, Gentili, Federica, Lotito, Antonio, Germanà, Bastianello, Russo, Nunzia, Grande, Giuseppe, Conigliaro, Rita, Cravero, Federico, Venezia, Giovanna, Marmo, Riccardo, Senneca, Piera, Milano, Angelo, Efthymakis, Konstantinos, Monica, Fabio, Montalto, Paolo, Lombardi, Mario, Morelli, Olivia, Castellani, Danilo, Nigro, Daniela, Festa, Roberto, Peralta, Sergio, Grasso, Maria, Privitera, Antonino Carlo, Di Stefano, Maria Emanuela, Scaccianoce, Giuseppe, Loiacono, Mariangela, Segato, Sergio, Balzarini, Marco, Usai Satta, Paolo, Lai, Mariantonia, and Manta, Raffaele

Abstract

Background/Aim:Prevalence of gastroduodenal endoscopic and histological lesions may modify over time due to different factors. We assessed both macroscopic and histological lesions currently detected at upper endoscopy performed in routine practice. Patients and Methods:Clinical, endoscopic, and histological data of consecutive adult patients referred for upper endoscopy in the 28 participating centres were analysed. Only patients who underwent the first endoscopic examination were considered. Prevalence of erosive/ulcerative lesions, cancers and extensive precancerous lesions in the stomach, and Helicobacter pyloriinfection was computed. Results:A total of 1,431 patients underwent endoscopy for gastro-oesophageal reflux symptoms (31.5%), dyspepsia (29.4%), or alarm symptoms (18.5%). Erosive oesophagitis or Barrett’s oesophagus was detected in 210 (14.7%) cases, peptic ulcer in 49 (3.4%), and a neoplastic lesion in 17 (1.2%). H. pyloriwas present in 201 (22.6%) cases, and extensive precancerous lesions on gastric mucosa in 46 (5.6%) patients. Gastric lesions were more prevalent in patients aged ≥50 years (26% vs. 18%; p= 0.001), and peptic ulcers were more frequently detected in patients with H. pylori(9.4% vs. 2.3%; p= 0.001) and in males (5.8% vs. 1.6%; p= 0.001), while neoplastic lesions in patients with alarm symptoms (3.8% vs. 0.6%; p= 0.001). Conclusions:The overall endoscopic lesions were more prevalent in patients aged ≥50 years, peptic ulcer and erosions were more frequent in H. pylori-infected patients, and extensive gastric precancerous lesions were present in less than 6% of cases.

Published
2024
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18. An Italian prospective multicenter study on colonoscopy practice and quality: What has changed in the last 10 years

Author

Testoni, Pier Alberto, primary, Notaristefano, Chiara, additional, Soncini, Marco, additional, Hassan, Cesare, additional, Monica, Fabio, additional, Radaelli, Franco, additional, Triossi, Omero, additional, Pasquale, Luigi, additional, Neri, Matteo, additional, Cannizzaro, Renato, additional, Leandro, Gioacchino, additional, Alvisi, Costanza, additional, Amato, Loretta, additional, Azzurro, Maurizio, additional, Benazzato, Luca, additional, Bianco, Maria Antonia, additional, Biviano, Ivano, additional, Bravi, Ivana, additional, Brunacci, Matteo, additional, Bucci, Cristina, additional, Buonocore, Matteo Rossano, additional, Cadoni, Sergio, additional, Camellini, Lorenzo, additional, Capone, Pietro, additional, Cavallaro, Lucas G., additional, Condino, Giovanna, additional, Crosta, Cristiano, additional, de Bellis, Mario, additional, de Colibus, Patrizia, additional, de Nigris, Francesca, additional, Esposito, Dario, additional, Fiori, Giancarla, additional, Fornasarig, Mara, additional, Fracchia, Mario, additional, Gemme, Carlo, additional, Germanà, Bastianello, additional, Gianni, Elena, additional, Giunta, Mariangela, additional, Guarnieri, Giovanni, additional, Iabichino, Giuseppe, additional, Luigiano, Carmelo, additional, Maiero, Stefania, additional, Marini, Mario, additional, Marone, Pietro, additional, Meucci, Costantino, additional, Morandi, Elisabetta, additional, Mura, Donatella, additional, Nucci, Andrea, additional, Peccianti, Caterina, additional, Praianò, Francesca, additional, Prisco, Antonio, additional, Rastelli, Carlotta, additional, Ravizza, Davide, additional, Rocca, Rodolfo, additional, Rosa, Cesare, additional, Rossi, Giovanni Battista, additional, Sannino, Angela, additional, Testoni, Sabrina, additional, and Urban, Flavia, additional

Published
2023
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19. Quality performance measures in upper gastrointestinal endoscopy for lesion detection: Italian AIGO-SIED-SIGE joint position statement

Author

De Francesco, Vincenzo, primary, Alicante, Saverio, additional, Amato, Arnaldo, additional, Frazzoni, Leonardo, additional, Lombardi, Giovanni, additional, Manfredi, Guido, additional, Monica, Fabio, additional, Sferrazza, Sandro, additional, Vassallo, Roberto, additional, Germanà, Bastianello, additional, Pasquale, Luigi, additional, Annibale, Bruno, additional, and Cadoni, Sergio, additional

Published
2022
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20. Real-time gastric juice analysis with EndoFaster for H. pylori diagnosis: a large, multicentre study

Author

Zullo, Angelo, primary, Germanà, Bastianello, additional, Galliani, Ermenegildo, additional, Iori, Andrea, additional, de Pretis, Giovanni, additional, Manfredi, Guido, additional, Buscarini, Elisabetta, additional, Ciuffi, Mario, additional, Ignomirelli, Orazio, additional, Farinati, Fabio, additional, Savarino, Edoardo, additional, Pallini, Paolo, additional, Milan, Luisa, additional, Conigliaro, Rita, additional, Grande, Giuseppe, additional, Cannizzaro, Renato, additional, Maiero, Stefania, additional, Pisani, Antonio, additional, Marangi, Stefania, additional, Manta, Raffaele, additional, Morelli, Olivia, additional, Peralta, Sergio, additional, Alessia, La Mantia, additional, Rossano Buonocore, Matteo, additional, and Monica, Fabio, additional

Published
2022
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21. Management of Helicobacter pylori infection: Guidelines of the Italian Society of Gastroenterology (SIGE) and the Italian Society of Digestive Endoscopy (SIED)

Author

Romano, Marco, primary, Gravina, Antonietta Gerarda, additional, Eusebi, Leonardo Henry, additional, Pellegrino, Raffaele, additional, Palladino, Giovanna, additional, Frazzoni, Leonardo, additional, Dajti, Elton, additional, Gasbarrini, Antonio, additional, Di Mario, Francesco, additional, Zagari, Rocco Maurizio, additional, Benedetti, Antonio, additional, Annibale, Bruno, additional, Burra, Patrizia, additional, Maida, Marcello Fabio, additional, Luzza, Francesco, additional, Ricciardiello, Luigi, additional, Vecchi, Maurizio, additional, Frulloni, Luca, additional, Repici, Alessandro, additional, Savarino, Edoardo Vincenzo, additional, Pasquale, Luigi, additional, Pisani, Antonio, additional, Lamazza, Antonietta, additional, Cengia, Gianpaolo, additional, Ciliberto, Enrico, additional, Conigliaro, Rita Luisa, additional, Da Massa Carrara, Paola, additional, and Germanà, Bastianello, additional

Published
2022
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22. A comparison of different strategies used to invite subjects with a positive faecal occult blood test to a colonoscopy assessment. A randomised controlled trial in population-based screening programmes

Author

Mel, Rosanna, Tison, Anna, Di Camillo, Sabrina, Germanà, Bastianello, Bisello, Marco, Lazzaro, Stefano, Antoniello, Luca Maria, Bertazzo, Sandra, Gennaro, Meris, Trevisani, Lucio, Cifalà, Viviana, Degl'Innocenti, Carolina, Migliori, Manola, Ciacci, Rosanna, Colamartini, Americo, Giuliani, Orietta, Vattiato, Rosa, Palumbo, Monica, Barca, Alessandra, Baiocchi, Diego, Quadrino, Francesco, Bellardini, Paola, Picchi, Alberto, Finucci, Giovanni, Coccioli, Sergio, Passamonti, Basilio Ubaldo, Malaspina, Morena, Tintori, Beatrice, D'Angelo, Valentina, Silvani, Marco, Fiorina, Giorgia, Capuano, Arianna, Segnan, Nereo, Zorzi, Manuel, Giorgi Rossi, Paolo, Cogo, Carla, Falcini, Fabio, Giorgi, Daniela, Grazzini, Grazia, Mariotti, Loretta, Matarese, Vincenzo, Soppelsa, Fabio, Senore, Carlo, and Ferro, Antonio

Published
2014
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23. White Paper of Italian Gastroenterology: Delivery of services for digestive diseases in Italy: Weaknesses and strengths

Author

Actis, Giovanni, Adamo, Salvatore, Amitrano, Lucio, Amuso, Mariano, Ancarani, Ornella, Angelico, Mario, Antonini, Filippo, Badiali, Danilo, Balzano, Antonio, Bardella, Maria Teresa, Barresi, Luca, Bellentani, Stefano, Bellini, Massimo, Benedetti, Antonio, Biagini, Massimiliano, Bianchi, Sabrina, Bianco, Antonietta, Borro, Paolo, Bortoli, Aurora, Bortoluzzi, Francesco, Borzio, Mauro, Boskovski, Ivo, Brosolo, Piero, Brunelli, Eugenio, Brunetto, Maurizia, Buri, Luigi, Burra, Patrizia, Caletti, Giancarlo, Chilovi, Fausto, Cicala, Michele, Ciliberto, Enrico, Cilona, Antonio, Cipolletta, Livio, Claar, Giovanni M., Conigliaro, Rita, Conio, Massimo, Corazziari, Enrico, Costamagna, Guido, Cottone, Mario, Craxì, Antonio, Crotta, Sergio, Cucchiara, Salvatore, Cupella, Francesco, Cuppone, Renato, D’Amico, Gennaro, D’Imperio, Nicola, De Angelis, Claudio, De Pretis, Giovanni, De Stefano, Salvatore, Del Favero, Giuseppe, Del Piano, Mario, Di Cillo, Michele, Di Leo, Alfredo, Di Matteo, Giovanni, Ederle, Andrea, Elli, Luca, Fagiuoli, Stefano, Familiari, Luigi, Familiari, Pietro, Fava, Gianmarco, Federici, Telemaco, Ferrini, Giovanni, Filiberti, Rosa, Fracasso, Pierluigi, Framarin, Luciana, Fregonese, Diego, Frosini, Giorgio, Frulloni, Luca, Fusaroli, Pietro, Gallo, Vincenzo, Gatto, Gianni, Gemme, Carlo, Germanà, Bastianello, Germani, Giacomo, Guardascione, Francesco, Gullotta, Renzo, Hassan, Cesare, Ingrosso, Marcello, Kohn, Anna, Lauri, Adriano, Leandro, Gioacchino, Leo, Piero, Lorenzini, Ivano, Loriga, Piero, Macarri, Giampiero, Magnolfi, Fabrizio, Manta, Raffaele, Marchi, Santino, Marin, Renato, Marini, Mario, Marino, Antonino, Meroni, Emanuele, Milazzo, Giuseppe, Monastra, Santo, Montalbano, Luigi, Morini, Sergio, Muscatiello, Nicola, Natali, Alessandro, Neri, Matteo, Nucci, Andrea, Pace, Fabio, Pallone, Francesco, Parodi, Maria Caterina, Pasquale, Luigi, Penagini, Roberto, Peralta, Sergio, Peruzzi, Egiziano, Piazzi, Lucia, Quondamcarlo, Cinzia, Radaelli, Franco, Rendina, Maria, Ridolfi, Francesco, Rosina, Floriano, Salmi, Andrea, Sansoè, Giovanni, Scafato, Emanuele, Scarpulla, Giuseppe, Solinas, Attilio, Soncini, Marco, Sorrentini, Italo, Spinzi, Giancarlo, Stroppa, Italo, Sturniolo, Giancarlo, Sumberaz, Alessandro, Tammaro, Leonardo, Tarantino, Ilaria, Testino, Gianni, Traina, Mario, Triossi, Omero, Usai-Satta, Paolo, Vilardo, Luigi, Virgilio, Clara, Zambelli, Alessandro, Zilli, Maurizio, Zullo, Angelo, Buscarini, Elisabetta, Conte, Dario, Cannizzaro, Renato, Bazzoli, Franco, De Boni, Michele, Delle Fave, Gianfranco, Farinati, Fabio, Ravelli, Paolo, Testoni, Pier Alberto, Lisiero, Manola, and Spolaore, Paolo

Published
2014
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25. Adherence to European Society of Gastrointestinal Endoscopy Quality Performance Measures for Upper and Lower Gastrointestinal Endoscopy: A Nationwide Survey From the Italian Society of Digestive Endoscopy

Author

Zagari, Rocco Maurizio, Frazzoni, Leonardo, Fuccio, Lorenzo, Bertani, Helga, Crinò, Stefano Francesco, Magarotto, Andrea, Dajti, Elton, Tringali, Andrea, Da Massa Carrara, Paola, Cengia, Gianpaolo, Ciliberto, Enrico, Conigliaro, Rita, Germanà, Bastianello, Lamazza, Antonietta, Pisani, Antonio, Spinzi, Giancarlo, Capelli, Maurizio, Bazzoli, Franco, Pasquale, Luigi, Zagari, Rocco Maurizio, Frazzoni, Leonardo, Fuccio, Lorenzo, Bertani, Helga, Crinò, Stefano Francesco, Magarotto, Andrea, Dajti, Elton, Tringali, Andrea, Da Massa Carrara, Paola, Cengia, Gianpaolo, Ciliberto, Enrico, Conigliaro, Rita, Germanà, Bastianello, Lamazza, Antonietta, Pisani, Antonio, Spinzi, Giancarlo, Capelli, Maurizio, Bazzoli, Franco, and Pasquale, Luigi

Subjects
quality, Settore MED/18 - CHIRURGIA GENERALE, ESGE, guidelines, General Medicine, endoscopy, guideline, performance measure
Abstract

BackgroundThe quality of gastrointestinal (GI) endoscopy has been recently identified as a major priority being associated with many outcomes and patient's experience.ObjectiveTo assess adherence of endoscopists to the European Society of Gastrointestinal Endoscopy (ESGE) quality performance measures for upper and lower GI endoscopy in Italy.MethodsAll endoscopist members of the Italian Society of Digestive Endoscopy (SIED) were invited from October 2018 to December 2018 to participate to a self-administered questionnaire-based survey. The questionnaire included questions on demographics and professional characteristics, and the recent ESGE quality performance measures for upper and lower GI endoscopy.ResultsA total of 392 endoscopists participated in the study. Only a minority (18.2%) of participants recorded the duration of esophagogastroduodenoscopy (EGD) and 51% provided accurate photo documentation in the minimum standard of 90% of cases. Almost all endoscopists correctly used Prague and Los Angeles classifications (87.8% and 98.2%, respectively), as well as Seattle and Management of precancerous conditions and lesions in the stomach (MAPS) biopsy protocols (86.5% and 91.4%, respectively). However, only 52.8% of participants monitored complications after therapeutic EGD, and 40.8% recorded patients with a diagnosis of Barrett's esophagus (BE). With regard to colonoscopy, almost all endoscopists (93.9%) used the Boston Bowel Preparation Scale for measuring bowel preparation quality and reported a cecal intubation rate ≥90%. However, about a quarter (26.2%) of participants reported an adenoma detection rate of ConclusionThe adherence of endoscopists to ESGE performance measures for GI endoscopy is sub-optimal in Italy. There is a need to disseminate and implement performance measures and endorse educational and scientific interventions on the quality of endoscopy.

Published
2022

26. Adenoma Detection Rate and Colorectal Cancer Risk in Fecal Immunochemical Test Screening Programs: An Observational Cohort Study.

Author

Zorzi, Manuel, Antonelli, Giulio, Barbiellini Amidei, Claudio, Battagello, Jessica, Germanà, Bastianello, Valiante, Flavio, Benvenuti, Stefano, Tringali, Alberto, Bortoluzzi, Francesco, Cervellin, Erica, Giacomin, Davide, Meggiato, Tamara, Rosa-Rizzotto, Erik, Fregonese, Diego, Dinca, Manuela, Baldassarre, Gianluca, Scalon, Paola, Pantalena, Maurizio, Milan, Luisa, and Bulighin, Gianmarco

Subjects
ADENOMA, MEDICAL screening, COLORECTAL cancer, DISEASE risk factors, COHORT analysis
Abstract

The adenoma detection rate (ADR) is defined as the proportion of screening colonoscopies in which at least 1 adenoma is detected. This study investigated the association between the ADR and the risk for colorectal cancer after colonoscopy that was prompted by a positive result on a fecal immunochemical test. Visual Abstract. ADR in FIT Screening Programs.: The adenoma detection rate (ADR) is defined as the proportion of screening colonoscopies in which at least 1 adenoma is detected. This study investigated the association between the ADR and the risk for colorectal cancer after colonoscopy that was prompted by a positive result on a fecal immunochemical test. Background: Colorectal cancer (CRC) screening programs based on fecal immunochemical tests (FITs) represent the standard of care for population-based interventions. Their benefit depends on the identification of neoplasia at colonoscopy after FIT positivity. Colonoscopy quality measured by adenoma detection rate (ADR) may affect screening program effectiveness. Objective: To examine the association between ADR and postcolonoscopy CRC (PCCRC) risk in a FIT-based screening program. Design: Retrospective population-based cohort study. Setting: Fecal immunochemical test–based CRC screening program between 2003 and 2021 in northeastern Italy. Patients: All patients with a positive FIT result who had a colonoscopy were included. Measurements: The regional cancer registry supplied information on any PCCRC diagnosed between 6 months and 10 years after colonoscopy. Endoscopists' ADR was categorized into 5 groups (20% to 39.9%, 40% to 44.9%, 45% to 49.9%, 50% to 54.9%, and 55% to 70%). To examine the association of ADR with PCCRC incidence risk, Cox regression models were fitted to estimate hazard ratios (HRs) and 95% CIs. Results: Of the 110 109 initial colonoscopies, 49 626 colonoscopies done by 113 endoscopists between 2012 and 2017 were included. After 328 778 person-years follow-up, 277 cases of PCCRC were diagnosed. Mean ADR was 48.3% (range, 23% and 70%). Incidence rates of PCCRC from lowest to highest ADR group were 13.13, 10.61, 7.60, 6.01, and 5.78 per 10 000 person-years. There was a significant inverse association between ADR and PCCRC incidence risk, with a 2.35-fold risk increase (95% CI, 1.63 to 3.38) in the lowest group compared with the highest. The adjusted HR for PCCRC associated with 1% increase in ADR was 0.96 (CI, 0.95 to 0.98). Limitation: Adenoma detection rate is partly determined by FIT positivity cutoff; exact values may vary in different settings. Conclusion: In a FIT-based screening program, ADR is inversely associated with PCCRC incidence risk, mandating appropriate colonoscopy quality monitoring in this setting. Increasing endoscopists' ADR may significantly reduce PCCRC risk. Primary Funding Source: None. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Etrolizumab versus infliximab for the treatment of moderately to severely active ulcerative colitis (GARDENIA): a randomised, double-blind, double-dummy, phase 3 study

Author

Danese, Silvio, primary, Colombel, Jean-Frederic, additional, Lukas, Milan, additional, Gisbert, Javier P, additional, D'Haens, Geert, additional, Hayee, Bu'hussain, additional, Panaccione, Remo, additional, Kim, Hyun-Soo, additional, Reinisch, Walter, additional, Tyrrell, Helen, additional, Oh, Young S, additional, Tole, Swati, additional, Chai, Akiko, additional, Chamberlain-James, Kirsten, additional, Tang, Meina Tao, additional, Schreiber, Stefan, additional, Aboo, Nazimuddin, additional, Ahmad, Tariq, additional, Aldeguer Mante, Xavier, additional, Allez, Matthieu, additional, Almer, Sven, additional, Altwegg, Romain, additional, Andreu Garcia, Montserrat, additional, Arasaradnam, Ramesh, additional, Ardizzone, Sandro, additional, Armuzzi, Alessandro, additional, Arnott, Ian, additional, Aumais, Guy, additional, Avni-Biron, Irit, additional, Barrow, Peter, additional, Beales, Ian, additional, Bermejo San Jose, Fernando, additional, Bezuidenhout, Abraham, additional, Biancone, Livia, additional, Blaeker, Michael, additional, Bloom, Stuart, additional, Bokemeyer, Bernd, additional, Bossa, Fabrizio, additional, Bossuyt, Peter, additional, Bouguen, Guillaume, additional, Bouhnik, Yoram, additional, Bouma, Gerd, additional, Bourdages, Raymond, additional, Bourreille, Arnaud, additional, Boustiere, Christian, additional, Brabec, Tomas, additional, Brand, Stephan, additional, Buening, Carsten, additional, Buisson, Anthony, additional, Cadiot, Guillaume, additional, Calvet Calvo, Xavier, additional, Carbonnel, Franck, additional, Carpio, Daniel, additional, Cheon, Jae Hee, additional, Chiba, Naoki, additional, Chioncel, Camelia, additional, Cimpoeru, Nicoleta-Claudia, additional, Clodi, Martin, additional, Corazza, Gino Roberto, additional, Cosintino, Rocco, additional, Cotter, Jose, additional, Creed, Thomas, additional, Cummings, Fraser, additional, Danese, Silvio, additional, de' Angelis, Gian Luigi, additional, De Maeyer, Marc, additional, Desai, Milind, additional, Desilets, Etienne, additional, Desreumaux, Pierre, additional, Dewit, Olivier, additional, Dinter, Johanna, additional, Dobru, Ecaterina Daniela, additional, Douda, Tomas, additional, Dumitrascu, Dan Lucian, additional, Ebert, Matthias, additional, Echarri Piudo, Ana, additional, Elkhashab, Magdy, additional, Eun, Chang Soo, additional, Feagan, Brian, additional, Fejes, Roland, additional, Fidalgo, Catarina, additional, Fishman, Sigal, additional, Flourié, Bernard, additional, Fowler, Sharyle, additional, Fries, Walter, additional, Fulop, Csaba, additional, Fumery, Mathurin, additional, G Kiss, Gyula, additional, Gassner, Sonja, additional, Gaya, Daniel, additional, Germanà, Bastianello, additional, Gheorghe, Liliana Simona, additional, Gilletta de Saint Joseph, Cyrielle, additional, Gionchetti, Paolo, additional, Goldis, Adrian-Eugen, additional, Gonçalves, Raquel, additional, Grimaud, Jean-Charles, additional, Gyökeres, Tibor, additional, Hagege, Herve, additional, Haidar, Andrei, additional, Hartmann, Heinz, additional, Hasselblatt, Peter, additional, Hayee, Buhussain, additional, Hebuterne, Xavier, additional, Hellström, Per, additional, Hindryckx, Pieter, additional, Hlavova, Helena, additional, Hoentjen, Frank, additional, Howaldt, Stefanie, additional, Hrdlicka, Ludek, additional, Huh, Kyu Chan, additional, Iborra Colomino, Maria Isabel, additional, Ionita-Radu, Florentina, additional, Irving, Peter, additional, Jahnsen, Jørgen, additional, Jang, ByungIk, additional, Jansen, Jeroen, additional, Jeon, Seong Woo, additional, Jover Martinez, Rodrigo, additional, Juillerat, Pascal, additional, Karlén, Per, additional, Kaser, Arthur, additional, Keil, Radan, additional, Kejariwal, Deepak, additional, Keret, Dan, additional, Khanna, Reena, additional, Kim, Dongwoo, additional, Kim, Duk Hwan, additional, Kim, Hyo-Jong, additional, Kim, Joo Sung, additional, Kim, Kueongok, additional, Kim, Kyung-Jo, additional, Kim, Sung Kook, additional, Kim, Young-Ho, additional, Klaus, Jochen, additional, Kohn, Anna, additional, Kojecky, Vladimir, additional, Koo, Ja Seol, additional, Kozak, Robert, additional, Kremer, Milan, additional, Kristof, Tunde, additional, Kruger, Frederik, additional, Laharie, David, additional, Lahat-zok, Adi, additional, Landa, Evgeny, additional, Lee, Jonghun, additional, Lee, Kang-Moon, additional, Lee, Kook Lae, additional, Lee, YooJin, additional, Lenze, Frank, additional, Lim, Wee Chian, additional, Limdi, Jimmy, additional, Lindsay, James, additional, Lopez Serrano, Pilar, additional, Louis, Edouard, additional, Lueth, Stefan, additional, Maconi, Giovanni, additional, Mana, Fazia, additional, Mann, Steven, additional, Mansfield, John, additional, Marchi, Santino, additional, Marino, Marco, additional, Marshall, John, additional, Martin Arranz, Maria Dolores, additional, Mateescu, Radu-Bogdan, additional, McLaughlin, John, additional, McLaughlin, Simon, additional, Melzer, Ehud, additional, Mertens, Jessica, additional, Mitrut, Paul, additional, Molnar, Tamas, additional, Muls, Vinciane, additional, Munuswamy, Pushpakaran, additional, Murray, Charles, additional, Naftali, Timna, additional, Naidoo, Visvakuren, additional, Nanabhay, Yusuf, additional, Negreanu, Lucian, additional, Nguyen, Augustin, additional, Ochsenkuehn, Thomas, additional, Orlando, Ambrogio, additional, Panes Diaz, Julian, additional, Paritsky, Maya, additional, Park, Dong Il, additional, Park, Jihye, additional, Pastorelli, Luca, additional, Peck-Radosavljevic, Markus, additional, Peerani, Farhad, additional, Perez Gisbert, Javier, additional, Peyrin-Biroulet, Laurent, additional, Picon, Laurence, additional, Pierik, Marieke, additional, Ponich, Terry, additional, Portela, Francisco, additional, Prins, Maartens Jeroen, additional, Racz, Istvan, additional, Rahman, Khan Fareed, additional, Reimund, Jean-Marie, additional, Reinshagen, Max, additional, Roblin, Xavier, additional, Rocca, Rodolfo, additional, Rogai, Francesca, additional, Rogler, Gerhard, additional, Salamon, Agnes, additional, Salazar, Ennaliza, additional, Sallo, Zoltan, additional, Samuel, Sunil, additional, Sans Cuffi, Miquel de los Santos, additional, Savarino, Edoardo Vincenzo, additional, Savarino, Vincenzo, additional, Savoye, Guillaume, additional, Seicean, Andrada, additional, Selinger, Christian, additional, Serra, David Martins, additional, Shim, Hang Hock, additional, Shin, SungJae, additional, Siegmund, Britta, additional, Siffledeen, Jesse, additional, Simmonds, Wayne, additional, Smid, Jan, additional, Sollano, Jose, additional, Song, Geun Am, additional, Speight, Alexander, additional, Sporea, Ioan, additional, Staessen, Dirk, additional, Stancu, George, additional, Steel, Alan, additional, Stepek, David, additional, Stoica, Victor, additional, Sturm, Andreas, additional, Szekely, Gyorgy, additional, Tan, Teck Kiang, additional, Taxonera Samso, Carlos, additional, Thomson, John, additional, Tichy, Michal, additional, Toth, Gabor Tamas, additional, Tulassay, Zsolt, additional, Vangeli, Marcello, additional, Varga, Marta, additional, Vieira, Ana, additional, Viennot, Stephanie, additional, Villa, Erica, additional, Vitek, Petr, additional, Vogelsang, Harald, additional, Vyhnalek, Petr, additional, Wahab, Peter, additional, Walldorf, Jens, additional, Ye, Byong Duk, additional, and Ziady, Christopher, additional

Published
2022
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28. Randomised controlled trial of mesalazine in IBS

Author

Barbara, Giovanni, Cremon, Cesare, Annese, Vito, Basilisco, Guido, Bazzoli, Franco, Bellini, Massimo, Benedetti, Antonio, Benini, Luigi, Bossa, Fabrizio, Buldrini, Paola, Cicala, Michele, Cuomo, Rosario, Germanà, Bastianello, Molteni, Paola, Neri, Matteo, Rodi, Marcello, Saggioro, Alfredo, Scribano, Maria Lia, Vecchi, Maurizio, Zoli, Giorgio, Corinaldesi, Roberto, and Stanghellini, Vincenzo

Published
2016
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29. Multisocieties position paper: Microbiological surveillance on flexible endoscopes

Author

Casini, Beatrice, primary, Pan, Angelo, additional, Guarini, Alessandra, additional, Rivara, Cinzia, additional, Zullo, Angelo, additional, Monica, Fabio, additional, Cimbro, Monica, additional, Casarano, Salvatore, additional, Inglese, Agostino, additional, Vaghi, Adriano, additional, Schiffino, Luigi, additional, Capezzuto, Erminio, additional, Da Massa Carrara, Paola, additional, Pasquale, Luigi, additional, Bertoni, Costanza, additional, Curti, Cesarina, additional, Giacomini, Maurizio, additional, Meledandri, Marcello, additional, Palmieri, Dalia, additional, Privitera, Gaetano, additional, Raglio, Annibale, additional, Tuvo, Benedetta, additional, Colombo, Benedetta, additional, Iannone, Teresa, additional, Iori, Giorgio, additional, Giaquinto, Antonella, additional, Minenna, Angela, additional, Petrocelli, Giulio, additional, Valdinoci, Monia, additional, Bortoluzzi, Francesco, additional, Galeazzi, Francesca, additional, Manta, Raffaele, additional, Montalto, Paolo, additional, Segato, Sergio, additional, Soncini, Marco, additional, Satta, Paolo Usai, additional, Vassallo, Roberto, additional, Ferraiolo, Fabio, additional, Roseto, Fabio, additional, Bezziccheri, Milena, additional, Fighera, Michele, additional, Giampà, Ada, additional, Mancini, Antonio, additional, Marino, Caterina, additional, Cerone, Marina Pisegna, additional, Risitano, Tommaso, additional, Sergio, Emmanuele, additional, Sinopoli, Raffaele, additional, De Caprio, Maria Teresa, additional, Failla, Giuseppe, additional, Agli, Luigi Lazzari, additional, Majori, Maria, additional, Toccaceli, Andrea, additional, Marciano, Emanuele, additional, Maurano, Attilio, additional, Rodella, Luca, additional, Cengia, Gianpaolo, additional, Ciliberto, Enrico, additional, Conigliaro, Rita, additional, Germanà, Bastianello, additional, Lamazza, Antonietta, additional, Pisani, Antonio, additional, Zagari, Rocco Maurizio, additional, and Spinzi, Giancarlo, additional

Published
2021
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30. Changes in digestive cancer diagnosis during the SARS-CoV-2 pandemic in Italy: A nationwide survey

Author

Buscarini, Elisabetta, primary, Benedetti, Antonio, additional, Monica, Fabio, additional, Pasquale, Luigi, additional, Buttitta, Francesco, additional, Cameletti, Michela, additional, Ferrari, Clarissa, additional, Ricciardiello, Luigi, additional, Massironi, Sara, additional, Bianco, Maria Antonia, additional, Germanà, Bastianello, additional, Rodinò, Stefano, additional, Anderloni, Andrea, additional, Mussetto, Alessandro, additional, Nipote, Bruno, additional, Russo, Salvatore, additional, Manta, Raffaele, additional, Lauri, Adriano, additional, Occhipinti, Vincenzo, additional, Marco, Marco Di, additional, Giovannone, Maurizio, additional, Binda, Cecilia, additional, Sbrancia, Monica, additional, Paolo, Maria Carla Di, additional, de’-Angelis, Gian Luigi, additional, Fiori, Giancarla, additional, Dal-Fante, Marco, additional, Caro, Giuseppe de, additional, Usai-Satta, Paolo, additional, Cesarini, Monica, additional, Piras, Enrico, additional, Stasi, Elisa, additional, Serio, Giovanni, additional, Montalbano, Luigi Maria, additional, Mirante, Vincenzo Giorgio, additional, Burattini, Osvaldo, additional, Attardo, Simona, additional, Bargiggia, Stefano, additional, Dinca, Manuele, additional, Missale, Guido, additional, Alvisi, Costanza, additional, Broglia, Francesco, additional, Ferraris, Luca, additional, Conti-Bellocchi, Maria Cristina, additional, Luigiano, Carmelo, additional, Pallio, Socrate, additional, Brunacci, Matteo, additional, Manfrini, Carlo, additional, Bozzi, Rosamaria, additional, Checchin, Davide, additional, Togliani, Thomas, additional, D'errico, Antonietta, additional, Bazzoli, Franco, additional, La Bianca, Orazio, additional, Berretti, Debora, additional, and Alvaro, Domenico, additional

Published
2021
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31. Manometric pattern progression in esophageal achalasia in the era of high-resolution manometry

Author

Salvador, Renato, Costantini, Mario, Tolone, Salvatore, Familiari, Pietro, Galliani, Ermenegildo, Germanà, Bastianello, Savarino, Edoardo, Merigliano, Stefano, Valmasoni, Michele, Familiari, Pietro (ORCID:0000-0002-5181-2928), Salvador, Renato, Costantini, Mario, Tolone, Salvatore, Familiari, Pietro, Galliani, Ermenegildo, Germanà, Bastianello, Savarino, Edoardo, Merigliano, Stefano, Valmasoni, Michele, and Familiari, Pietro (ORCID:0000-0002-5181-2928)

Abstract

Esophageal manometry represents the gold standard technique for the diagnosis of esophageal achalasia because it can detect both the lack of lower esophageal sphincter (LES) relaxation and abnormal peristalsis. From the manometric standpoint, cases of achalasia can be segregated on the grounds of three clinically relevant patterns according to the Chicago Classification v3.0. It is currently unclear whether they represent distinct entities or are part of a disease continuum with the possibility of transition from a pattern to another one. The four cases described in the present report could provide further insights on this topic because the manometric pattern changed from type III to type II in all patients-without any invasive treatment. The cases described here support the hypothesis that the different manometric patterns of achalasia represent different stages in the evolution of the same disease, type III being the early stage, type II an intermediate stage, and type I probably the end stage of achalasia.

Published
2021

34. Distinguishing features between patients with acute diverticulitis and diverticular bleeding: Results from the REMAD registry

Author

Carabotti, Marilia, primary, Morselli Labate, Antonio M, additional, Cremon, Cesare, additional, Cuomo, Rosario, additional, Pace, Fabio, additional, Andreozzi, Paolo, additional, Falangone, Francesca, additional, Barbara, Giovanni, additional, Annibale, Bruno, additional, Andrealli, Alida, additional, Andriulli, Angelo, additional, Ardizzone, Sandro, additional, Astegiano, Marco, additional, Bachetti, Francesco, additional, Bartolozzi, Simona, additional, Bargiggia, Stefano, additional, Bassotti, Gabrio, additional, Bianco, Maria Antonia, additional, Binda, Gian Andrea, additional, Biscaglia, Giuseppe, additional, Bosani, Matteo, additional, Bottiglieri, Maria Erminia, additional, Cargiolli, Martina, additional, Ciacci, Carolina, additional, Colecchia, Antonio, additional, Dell'Era, Alessandra, additional, De Matthaeis, Marina, additional, Di Ciaula, Agostino, additional, Di Ruscio, Mirko, additional, Dinelli, Marco, additional, Festa, Virginia, additional, Festi, Davide, additional, Galliani, Ermenegildo, additional, Germanà, Bastianello, additional, Grassini, Mario, additional, Guido, Ennio, additional, Iafrate, Franco, additional, Iovino, Paola, additional, Iuliano, Donato, additional, Laghi, Andrea, additional, Latella, Giovanni, additional, Manes, Giampiero, additional, Marabotto, Elisa, additional, Marchi, Santino, additional, Mauro, Biagio, additional, Maurano, Attilio, additional, Moscatelli, Alessandro, additional, Nascimbeni, Riccardo, additional, Neri, Matteo, additional, Occhipinti, Pietro, additional, Parravicini, Marco, additional, Pennazio, Marco, additional, Peralta, Sergio, additional, Portincasa, Piero, additional, Radaelli, Franco, additional, Reati, Raffaella, additional, Redaelli, Alessandro, additional, Rossi, Marco, additional, Salerno, Raffale, additional, Savarino, Vincenzo, additional, Segato, Sergio, additional, Severi, Carola, additional, Scaccianoce, Giuseppe, additional, Usai, Paolo, additional, Valle, Valentina, additional, and Virgilio, Clara, additional

Published
2021
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35. Real-time gastric juice analysis with EndoFaster for H. pyloridiagnosis: a large, multicentre study

Author

Zullo, Angelo, Germanà, Bastianello, Galliani, Ermenegildo, Iori, Andrea, de Pretis, Giovanni, Manfredi, Guido, Buscarini, Elisabetta, Ciuffi, Mario, Ignomirelli, Orazio, Farinati, Fabio, Savarino, Edoardo, Pallini, Paolo, Milan, Luisa, Conigliaro, Rita, Grande, Giuseppe, Cannizzaro, Renato, Maiero, Stefania, Pisani, Antonio, Marangi, Stefania, Manta, Raffaele, Morelli, Olivia, Peralta, Sergio, Alessia, La Mantia, Rossano Buonocore, Matteo, and Monica, Fabio

Published
2022
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36. Adenoma detection by Endocuff-assisted versus standard colonoscopy in an organized screening program: the "ItaVision" randomized controlled trial.

Author

Zorzi, Manuel, Hassan, Cesare, Battagello, Jessica, Antonelli, Giulio, Pantalena, Maurizio, Bulighin, Gianmarco, Alicante, Saverio, Meggiato, Tamara, Rosa-Rizzotto, Erik, Iacopini, Federico, Luigiano, Carmelo, Monica, Fabio, Arrigoni, Arrigo, Germanà, Bastianello, Valiante, Flavio, Mallardi, Beatrice, Senore, Carlo, Grazzini, Grazia, Mantellini, Paola, and ItaVision Working Group

Subjects
ADENOMA, MEDICAL screening, COLONOSCOPY, CONFIDENCE intervals, RESEARCH, COLON (Anatomy), CLINICAL trials, RESEARCH methodology, EARLY detection of cancer, EVALUATION research, COLORECTAL cancer, COMPARATIVE studies, FECAL occult blood tests
Abstract

Background: The Endocuff Vision device (Arc Medical Design Ltd., Leeds, UK) has been shown to increase mucosal exposure, and consequently adenoma detection rate (ADR), during colonoscopy. This nationwide multicenter study assessed possible benefits and harms of using Endocuff Vision in a fecal immunochemical test (FIT)-based screening program.Methods: Patients undergoing colonoscopy after a FIT-positive test were randomized 1:1 to undergo Endocuff-assisted colonoscopy or standard colonoscopy, stratified by sex, age, and screening history. Primary outcome was ADR. Secondary outcomes were ADR stratified by endoscopists' ADR, advanced ADR (AADR), adenomas per colonoscopy (APC), withdrawal time, and adverse events.Results: 1866 patients were enrolled across 13 centers. After exclusions, 1813 (mean age 60.1 years; male 53.8 %) were randomized (908 Endocuff Vision, 905 standard colonoscopy). ADR was significantly higher in the Endocuff Vision arm (47.8 % vs. 40.8 %; relative risk [RR] 1.17, 95 % confidence interval [CI] 1.06-1.30), with no differences between arms regarding size or morphology. When stratifying for endoscopists' ADR, only low detectors (ADR < 33.3 %) showed a statistically significant ADR increase (Endocuff Vision 41.1 % [95 %CI 35.7-46.7] vs. standard colonoscopy 26.0 % [95 %CI 21.3-31.4]). AADR (24.8 % vs. 20.5 %, RR 1.21, 95 %CI 1.02-1.43) and APC (0.94 vs. 0.77; P  = 0.001) were higher in the Endocuff Vision arm. Withdrawal time and adverse events were similar between arms.Conclusion: Endocuff Vision increased ADR in a FIT-based screening program by improving examination of the whole colonic mucosa. Utility was highest among endoscopists with a low ADR. [ABSTRACT FROM AUTHOR]

Published
2022
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38. First-line endoscopic treatment with over-the-scope clips in patients with either upper or lower gastrointestinal bleeding: a multicenter study

Author

Manta, Raffaele, additional, Mangiafico, Santi, additional, Zullo, Angelo, additional, Bertani, Helga, additional, Caruso, Angelo, additional, Grande, Giuseppe, additional, Zito, Francesco Paolo, additional, Mangiavillano, Benedetto, additional, Pasquale, Luigi, additional, Parodi, Andrea, additional, Germanà, Bastianello, additional, Bassotti, Gabrio, additional, Monica, Fabio, additional, Zilli, Maurizio, additional, Pisani, Antonio, additional, Mutignani, Massimiliano, additional, Conigliaro, Rita, additional, and Galloro, Giuseppe, additional

Published
2018
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39. Fecal Clostridiales distribution and short-chain fatty acids reflect bowel habits in irritable bowel syndrome

Author

Gargari, Giorgio, primary, Taverniti, Valentina, additional, Gardana, Claudio, additional, Cremon, Cesare, additional, Canducci, Filippo, additional, Pagano, Isabella, additional, Barbaro, Maria Raffaella, additional, Bellacosa, Lara, additional, Castellazzi, Anna Maria, additional, Valsecchi, Chiara, additional, Tagliacarne, Sara Carlotta, additional, Bellini, Massimo, additional, Bertani, Lorenzo, additional, Gambaccini, Dario, additional, Marchi, Santino, additional, Cicala, Michele, additional, Germanà, Bastianello, additional, Dal Pont, Elisabetta, additional, Vecchi, Maurizio, additional, Ogliari, Cristina, additional, Fiore, Walter, additional, Stanghellini, Vincenzo, additional, Barbara, Giovanni, additional, and Guglielmetti, Simone, additional

Published
2018
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40. Effect of Lactobacillus paracasei CNCM I‐1572 on symptoms, gut microbiota, short chain fatty acids, and immune activation in patients with irritable bowel syndrome: A pilot randomized clinical trial

Author

Cremon, Cesare, primary, Guglielmetti, Simone, additional, Gargari, Giorgio, additional, Taverniti, Valentina, additional, Castellazzi, Anna Maria, additional, Valsecchi, Chiara, additional, Tagliacarne, Carlotta, additional, Fiore, Walter, additional, Bellini, Massimo, additional, Bertani, Lorenzo, additional, Gambaccini, Dario, additional, Cicala, Michele, additional, Germanà, Bastianello, additional, Vecchi, Maurizio, additional, Pagano, Isabella, additional, Barbaro, Maria Raffaella, additional, Bellacosa, Lara, additional, Stanghellini, Vincenzo, additional, and Barbara, Giovanni, additional

Published
2018
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42. Real-time EndoFaster improves Helicobacter pyloridetection in chronic active gastritis

Author

Zullo, Angelo, Germanà, Bastianello, Galliani, Ermenegildo, Iori, Andrea, De Pretis, Giovanni, Manfredi, Guido, Buscarini, Elisabetta, Guarnieri, Giovanni, Cannizzaro, Renato, Buonocore, Matteo Rossano, and Monica, Fabio

Abstract

Helicobacter pyloriis the most frequent cause of chronic active gastritis (CAG), namely the first step for gastric cancer development. When infection is not detected at histology, another test is advised. EndoFaster is novel device that reveal the presence of H. pyloriby determining ammonium concentration in the gastric juice during endoscopy. We evaluated whether this test may improve etiological diagnosis in CAG patients. In 595 consecutive patients who underwent upper endoscopy gastric juice was analysed with EndoFaster and standard biopsies were taken. CAG with typical bacteria was detected in 102 (17.1%) patients, and CAG without H. pyloriwas found in 36 (6.3%) cases. EndoFaster detected the infection in 22 (61.1%) of these patients. Neither ongoing proton pump inhibitor therapy nor previous eradication therapy affect the test accuracy. By using EndoFaster, another test to search for the infection in H. pylori-negative CAG patients may be avoided in more than 60% of cases, impacting on both patients discomfort and health resources use.

Published
2022
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44. Corrigendum to “A comparison of different strategies used to invite subjects with a positive faecal occult blood test to a colonoscopy assessment. A randomized controlled trial in population-based screening programmes” [Prev. Med. 65 (2014) 70–76]

Author

Zorzi, Manuel, primary, Rossi, Paolo Giorgi, additional, Cogo, Carla, additional, Falcini, Fabio, additional, Giorgi, Daniela, additional, Grazzini, Grazia, additional, Mariotti, Loretta, additional, Matarese, Vincenzo, additional, Soppelsa, Fabio, additional, Senore, Carlo, additional, Ferro, Antonio, additional, Mel, Rosanna, additional, Tison, Anna, additional, Di Camillo, Sabrina, additional, Germanà, Bastianello, additional, Bisello, Marco, additional, Lazzaro, Stefano, additional, Antoniello, Luca Maria, additional, Bertazzo, Sandra, additional, Gennaro, Meris, additional, Trevisani, Lucio, additional, Cifalà, Viviana, additional, Degl'Innocenti, Carolina, additional, Migliori, Manola, additional, Ciacci, Rosanna, additional, Colamartini, Americo, additional, Giuliani, Orietta, additional, Vattiato, Rosa, additional, Palumbo, Monica, additional, Barca, Alessandra, additional, Baiocchi, Diego, additional, Quadrino, Francesco, additional, Bellardini, Paola, additional, Picchi, Alberto, additional, Finucci, Giovanni, additional, Coccioli, Sergio, additional, Passamonti, Basilio Ubaldo, additional, Malaspina, Morena, additional, Tintori, Beatrice, additional, D'Angelo, Valentina, additional, Silvani, Marco, additional, Fiorina, Giorgia, additional, Capuano, Arianna, additional, and Segnan, Nereo, additional

Published
2015
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45. Randomised controlled trial of mesalazine in IBS

Author

Barbara, Giovanni, primary, Cremon, Cesare, additional, Annese, Vito, additional, Basilisco, Guido, additional, Bazzoli, Franco, additional, Bellini, Massimo, additional, Benedetti, Antonio, additional, Benini, Luigi, additional, Bossa, Fabrizio, additional, Buldrini, Paola, additional, Cicala, Michele, additional, Cuomo, Rosario, additional, Germanà, Bastianello, additional, Molteni, Paola, additional, Neri, Matteo, additional, Rodi, Marcello, additional, Saggioro, Alfredo, additional, Scribano, Maria Lia, additional, Vecchi, Maurizio, additional, Zoli, Giorgio, additional, Corinaldesi, Roberto, additional, and Stanghellini, Vincenzo, additional

Published
2014
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46. Development and Validation of an Endoscopic Classification of Diverticular Disease of the Colon: The DICA Classification

Author

Tursi, Antonio, primary, Brandimarte, Giovanni, additional, Di Mario, Francesco, additional, Andreoli, Arnaldo, additional, Annunziata, Maria Laura, additional, Astegiano, Marco, additional, Bianco, Maria Antonietta, additional, Buri, Luigi, additional, Cammarota, Giovanni, additional, Capezzuto, Erminio, additional, Chilovi, Fausto, additional, Cianci, Massimo, additional, Conigliaro, Rita, additional, Del Favero, Giuseppe, additional, Di Cesare, Luigi, additional, Di Fonzo, Michela, additional, Elisei, Walter, additional, Faggiani, Roberto, additional, Farroni, Ferruccio, additional, Forti, Giacomo, additional, Germanà, Bastianello, additional, Giorgetti, Gian Marco, additional, Giovannone, Maurizio, additional, Lecca, Piera Giuseppina, additional, Loperfido, Silvano, additional, Marmo, Riccardo, additional, Morucci, Piero, additional, Occhigrossi, Giuseppe, additional, Penna, Antonio, additional, Rossi, Alfredo Francesco, additional, Spadaccini, Antonio, additional, Zampaletta, Costantino, additional, Zilli, Maurizio, additional, Zullo, Angelo, additional, Scarpignato, Carmelo, additional, and Picchio, Marcello, additional

Published
2014
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47. A comparison of different strategies used to invite subjects with a positive faecal occult blood test to a colonoscopy assessment. A randomised controlled trial in population-based screening programmes

Author

Zorzi, Manuel, primary, Giorgi Rossi, Paolo, additional, Cogo, Carla, additional, Falcini, Fabio, additional, Giorgi, Daniela, additional, Grazzini, Grazia, additional, Mariotti, Loretta, additional, Matarese, Vincenzo, additional, Soppelsa, Fabio, additional, Senore, Carlo, additional, Ferro, Antonio, additional, Mel, Rosanna, additional, Tison, Anna, additional, Di Camillo, Sabrina, additional, Germanà, Bastianello, additional, Bisello, Marco, additional, Lazzaro, Stefano, additional, Antoniello, Luca Maria, additional, Bertazzo, Sandra, additional, Gennaro, Meris, additional, Trevisani, Lucio, additional, Cifalà, Viviana, additional, Degl'Innocenti, Carolina, additional, Migliori, Manola, additional, Ciacci, Rosanna, additional, Colamartini, Americo, additional, Giuliani, Orietta, additional, Vattiato, Rosa, additional, Palumbo, Monica, additional, Barca, Alessandra, additional, Baiocchi, Diego, additional, Quadrino, Francesco, additional, Bellardini, Paola, additional, Picchi, Alberto, additional, Finucci, Giovanni, additional, Coccioli, Sergio, additional, Passamonti, Basilio Ubaldo, additional, Malaspina, Morena, additional, Tintori, Beatrice, additional, D'Angelo, Valentina, additional, Silvani, Marco, additional, Fiorina, Giorgia, additional, Capuano, Arianna, additional, and Segnan, Nereo, additional

Published
2014
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48. White Paper of Italian Gastroenterology: Delivery of services for digestive diseases in Italy: Weaknesses and strengths

Author

Buscarini, Elisabetta, primary, Conte, Dario, additional, Cannizzaro, Renato, additional, Bazzoli, Franco, additional, De Boni, Michele, additional, Delle Fave, Gianfranco, additional, Farinati, Fabio, additional, Ravelli, Paolo, additional, Testoni, Pier Alberto, additional, Lisiero, Manola, additional, Spolaore, Paolo, additional, Actis, Giovanni, additional, Adamo, Salvatore, additional, Amitrano, Lucio, additional, Amuso, Mariano, additional, Ancarani, Ornella, additional, Angelico, Mario, additional, Antonini, Filippo, additional, Badiali, Danilo, additional, Balzano, Antonio, additional, Bardella, Maria Teresa, additional, Barresi, Luca, additional, Bellentani, Stefano, additional, Bellini, Massimo, additional, Benedetti, Antonio, additional, Biagini, Massimiliano, additional, Bianchi, Sabrina, additional, Bianco, Antonietta, additional, Borro, Paolo, additional, Bortoli, Aurora, additional, Bortoluzzi, Francesco, additional, Borzio, Mauro, additional, Boskovski, Ivo, additional, Brosolo, Piero, additional, Brunelli, Eugenio, additional, Brunetto, Maurizia, additional, Buri, Luigi, additional, Burra, Patrizia, additional, Caletti, Giancarlo, additional, Chilovi, Fausto, additional, Cicala, Michele, additional, Ciliberto, Enrico, additional, Cilona, Antonio, additional, Cipolletta, Livio, additional, Claar, Giovanni M., additional, Conigliaro, Rita, additional, Conio, Massimo, additional, Corazziari, Enrico, additional, Costamagna, Guido, additional, Cottone, Mario, additional, Craxì, Antonio, additional, Crotta, Sergio, additional, Cucchiara, Salvatore, additional, Cupella, Francesco, additional, Cuppone, Renato, additional, D’Amico, Gennaro, additional, D’Imperio, Nicola, additional, De Angelis, Claudio, additional, De Pretis, Giovanni, additional, De Stefano, Salvatore, additional, Del Favero, Giuseppe, additional, Del Piano, Mario, additional, Di Cillo, Michele, additional, Di Leo, Alfredo, additional, Di Matteo, Giovanni, additional, Ederle, Andrea, additional, Elli, Luca, additional, Fagiuoli, Stefano, additional, Familiari, Luigi, additional, Familiari, Pietro, additional, Fava, Gianmarco, additional, Federici, Telemaco, additional, Ferrini, Giovanni, additional, Filiberti, Rosa, additional, Fracasso, Pierluigi, additional, Framarin, Luciana, additional, Fregonese, Diego, additional, Frosini, Giorgio, additional, Frulloni, Luca, additional, Fusaroli, Pietro, additional, Gallo, Vincenzo, additional, Gatto, Gianni, additional, Gemme, Carlo, additional, Germanà, Bastianello, additional, Germani, Giacomo, additional, Guardascione, Francesco, additional, Gullotta, Renzo, additional, Hassan, Cesare, additional, Ingrosso, Marcello, additional, Kohn, Anna, additional, Lauri, Adriano, additional, Leandro, Gioacchino, additional, Leo, Piero, additional, Lorenzini, Ivano, additional, Loriga, Piero, additional, Macarri, Giampiero, additional, Magnolfi, Fabrizio, additional, Manta, Raffaele, additional, Marchi, Santino, additional, Marin, Renato, additional, Marini, Mario, additional, Marino, Antonino, additional, Meroni, Emanuele, additional, Milazzo, Giuseppe, additional, Monastra, Santo, additional, Montalbano, Luigi, additional, Morini, Sergio, additional, Muscatiello, Nicola, additional, Natali, Alessandro, additional, Neri, Matteo, additional, Nucci, Andrea, additional, Pace, Fabio, additional, Pallone, Francesco, additional, Parodi, Maria Caterina, additional, Pasquale, Luigi, additional, Penagini, Roberto, additional, Peralta, Sergio, additional, Peruzzi, Egiziano, additional, Piazzi, Lucia, additional, Quondamcarlo, Cinzia, additional, Radaelli, Franco, additional, Rendina, Maria, additional, Ridolfi, Francesco, additional, Rosina, Floriano, additional, Salmi, Andrea, additional, Sansoè, Giovanni, additional, Scafato, Emanuele, additional, Scarpulla, Giuseppe, additional, Solinas, Attilio, additional, Soncini, Marco, additional, Sorrentini, Italo, additional, Spinzi, Giancarlo, additional, Stroppa, Italo, additional, Sturniolo, Giancarlo, additional, Sumberaz, Alessandro, additional, Tammaro, Leonardo, additional, Tarantino, Ilaria, additional, Testino, Gianni, additional, Traina, Mario, additional, Triossi, Omero, additional, Usai-Satta, Paolo, additional, Vilardo, Luigi, additional, Virgilio, Clara, additional, Zambelli, Alessandro, additional, Zilli, Maurizio, additional, and Zullo, Angelo, additional

Published
2014
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49. Effect of Lactobacillus paracaseiCNCM I-1572 on symptoms, gut microbiota, short chain fatty acids, and immune activation in patients with irritable bowel syndrome: A pilot randomized clinical trial

Author

Cremon, Cesare, Guglielmetti, Simone, Gargari, Giorgio, Taverniti, Valentina, Castellazzi, Anna Maria, Valsecchi, Chiara, Tagliacarne, Carlotta, Fiore, Walter, Bellini, Massimo, Bertani, Lorenzo, Gambaccini, Dario, Cicala, Michele, Germanà, Bastianello, Vecchi, Maurizio, Pagano, Isabella, Barbaro, Maria Raffaella, Bellacosa, Lara, Stanghellini, Vincenzo, and Barbara, Giovanni

Abstract

Evidence suggests a role of intestinal microbiota-host interactions in the pathophysiology and symptoms of irritable bowel syndrome (IBS). The objective of this article is to assess the effects of Lactobacillus paracaseiCNCM I-1572 on clinical and gut microbiota-related factors in IBS. We conducted a multicenter, randomized, double-blind, cross-over, 18-week, placebo-controlled, pilot trial assessing the effect of Lactobacillus paracaseiCNCM I-1572 on symptoms, gut microbiota composition, fecal short chain fatty acid (SCFA), immunoglobulin A, and cytokines in IBS. The intestinal microbial ecosystem was characterized by 16S rRNA gene profiling. Forty IBS patients were enrolled from five Italian centers. Lactobacillus paracaseiCNCM I-1572 did not significantly improve IBS symptoms, including primary efficacy variables worst abdominal pain/discomfort and IBS degree of relief. Interestingly, Lactobacillus paracaseiCNCM I-1572 induced a significant reduction in genus Ruminococcus, dominated by taxa related to Ruminococcus bromiiand Ruminococcus callidus, a significant increase in the SCFAs acetate and butyrate, and a significant reduction in the pro-inflammatory cytokine interleukin-15. This pilot study shows that Lactobacillus paracaseiCNCM I-1572 is able to modulate gut microbiota structure/function and reduce immune activation in IBS. As no statistically significant effect on IBS-symptoms was found, further studies are necessary to determine the role of this probiotic in IBS. The study was registered at ClinicalTrials.gov registry under identifier NCT02371499.

Published
2018
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