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1. Diagnosis and treatment of Tropheryma whipplei infection in patients with inflammatory rheumatic disease: Data from the French Tw-IRD registry

Author

Caillet Portillo, Damien, Puéchal, Xavier, Masson, Maëva, Kostine, Marie, Michaut, Alexia, Ramon, André, Wendling, Daniel, Costedoat-Chalumeau, Nathalie, Richette, Pascal, Marotte, Hubert, Vix-Portet, Justine, Dubost, Jean-Jacques, Ottaviani, Sébastien, Mouterde, Gaël, Grasland, Anne, Frazier, Aline, Germain, Vincent, Coury, Fabienne, Tournadre, Anne, Soubrier, Martin, Cavalie, Laurent, Brevet, Pauline, Zabraniecki, Laurent, Jamard, Bénédicte, Couture, Guillaume, Arnaud, Laurent, Richez, Christophe, Degboé, Yannick, Ruyssen-witrand, Adeline, and Constantin, Arnaud

Published
2024
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2. Diagnosis and treatment of Tropheryma whipplei infection in patients with inflammatory rheumatic disease: data from the French Tw-IRD registry

Author

Caillet Portillo, Damien, primary, Puéchal, Xavier, additional, Masson, Maëva, additional, Kostine, Marie, additional, Michaut, Alexia, additional, Ramon, André, additional, Wendling, Daniel, additional, Costedoat-Chalumeau, Nathalie, additional, Richette, Pascal, additional, Marotte, Hubert, additional, Vix-Portet, Justine, additional, Dubost, Jean-Jacques, additional, Ottaviani, Sébastien, additional, Mouterdre, Gaël, additional, Grasland, Anne, additional, Frazier, Aline, additional, Germain, Vincent, additional, Coury, Fabienne, additional, Tournadre, Anne, additional, Soubrier, Martin, additional, Cavalie, Laurent, additional, Brevet, Pauline, additional, Zabraniecki, Laurent, additional, Jamard, Bénédicte, additional, Couture, Guillaume, additional, Arnaud, Laurent, additional, Richez, Christophe, additional, Degboé, Yannick, additional, Ruyssen-witrand, Adeline, additional, and Constantin, Arnaud, additional

Published
2023
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4. Evolution of monoclonal gammopathy of undetermined significance in patients treated with JAK inhibitors for rheumatic diseases: data from the MAJIK-SFR registry.

Author

Faganello, Déborah, Bertrand, Anne, Meunier, Pauline, Avouac, Jérôme, Toussirot, Eric, Coury, Fabienne, Seror, Raphaele, Mélédo, Guillaume Le, Germain, Vincent, Dellal, Azedinne, Shima, Ditmar, Hulin, Cyrille, Prati, Clément, Schaeverbeke, Thierry, Richez, Christophe, Truchetet, Marie-Elise, and Kostine, Marie

Subjects
DRUG therapy for rheumatism, RHEUMATOID arthritis diagnosis, REPORTING of diseases, PATIENT aftercare, PROTEINS, JANUS kinases, MONOCLONAL gammopathies, CONTENT mining, DESCRIPTIVE statistics, RESEARCH funding, NEUROTRANSMITTER uptake inhibitors, PHARMACODYNAMICS
Abstract

Objective Monoclonal gammopathy of undetermined significance (MGUS) is common, but there are scarce data regarding the effect of DMARDs on this premalignant condition. We aimed to evaluate the impact of JAK inhibitors (JAKis) on MGUS when initiated for an active rheumatic disease. Methods Patients with monoclonal abnormality prior to JAKi initiation for an active rheumatic disease were identified through the MAJIK-SFR Registry, a French multicentre prospective study. Clinical and biological data were collected using a standardized case report form. Results Twenty patients were identified with a mean age of 65 years and a diagnosis of RA (n  = 15), PsA (n  = 3), and axial SpA (n  = 2). The JAKi prescribed was baricitinib (n  = 9), tofacitinib (n  = 6) or upadacitinib (n  = 5), with a mean duration of 15.5 months. Seventeen patients had individualized serum monoclonal protein (IgG kappa n  = 9; IgG lambda n  = 4; IgM kappa n  = 3; IgA lambda n  = 1) ranging from 0.16 to 2.3 g/dl, and three patients did not have an initial measurable spike but they had a positive serum immunofixation. With a follow-up of 4–28 months, the serum monoclonal protein level decreased in 8 of 17 patients (47%), remained stable in 8 patients (47%) and increased in 1 patient (6%). The maximal decrease observed was an initial IgG kappa of 2.3 g/dl, decreasing to 0.2 g/dl at month 14. Conclusion This study provides reassuring and promising data on MGUS evolution in patients treated with JAKis for rheumatic diseases, which may guide the choice of treatment in patients with both conditions. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Statistics of Particle Trajectories at Short Time Intervals Reveal fN-Scale Colloidal Forces

Author

Sainis, Sunil K., Germain, Vincent, and Dufresne, Eric R.

Subjects
Condensed Matter - Soft Condensed Matter, Condensed Matter - Statistical Mechanics
Abstract

We describe and implement a technique for extracting forces from the relaxation of an overdamped thermal system with normal modes. At sufficiently short time intervals, the evolution of a normal mode is well described by a one-dimensional Smoluchowski equation with constant drift velocity, v, and diffusion coefficient, D. By virtue of fluctuation-dissipation, these transport coefficients are simply related to conservative forces, F, acting on the normal mode: F = k_BT v/D. This relationship implicitly accounts for hydrodynamic interactions, requires no mechanical calibration, makes no assumptions about the form of conservative forces, and requires no prior knowledge of material properties. We apply this method to measure the electrostatic interactions of polymer microspheres suspended in nonpolar microemulsions., Comment: 4 pages, 3 figures

Published
2007
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7. Evolution of monoclonal gammopathy of undetermined significance in patients treated with JAK inhibitors for rheumatic diseases: data from the MAJIK-SFR registry

Author

Faganello, Déborah, primary, Bertrand, Anne, additional, Meunier, Pauline, additional, Avouac, Jérôme, additional, Toussirot, Eric, additional, Coury, Fabienne, additional, Seror, Raphaele, additional, Le Mélédo, Guillaume, additional, Germain, Vincent, additional, Dellal, Azedinne, additional, Shima, Ditmar, additional, Hulin, Cyrille, additional, Prati, Clément, additional, Schaeverbeke, Thierry, additional, Richez, Christophe, additional, Truchetet, Marie-Elise, additional, and Kostine, Marie, additional

Published
2023
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8. Use of a bDMARD or tsDMARD for the management of inflammatory arthritis under checkpoint inhibitors: an observational study

Author

De La Fuente, Fanny, primary, Belkhir, Rakiba, additional, Henry, Julien, additional, Nguyen, Chi Duc, additional, Pham, Thao, additional, Germain, Vincent, additional, Gavand, Pierre Edouard, additional, Labadie, Céline, additional, Briere, Claire, additional, Lauret, Ambre, additional, Cardon, Thierry, additional, Mouterde, Gael, additional, Bonnet, Isabelle, additional, Rouxel, Léa, additional, Truchetet, Marie-Elise, additional, Schaeverbeke, Thierry, additional, Richez, Christophe, additional, and Kostine, Marie, additional

Published
2022
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9. New deeply coloured 18-K gold materials built by nanotechnologies

Author

Serin, Anne, Bourlion, Mathieu, Diologent, Frederic, Ziegenhagen, Rene, and Germain, Vincent

Subjects
Nanoparticles, Gold -- Properties, Nanotechnology -- Methods -- Forecasts and trends, Metals, metalworking and machinery industries
Abstract

A new way to elaborate coloured carat gold materials has been developed. Instead of using traditional metallurgy route, we built a new 18-K bulk material using nanostructured gold particles. The resulting colour is the consequence of a well-known property of gold nanoparticles: the surface plasmon resonance effect. Depending on the chemical environment around the nanoparticles, their shape and size, it is possible to tune the colour of gold. Thanks to this property, it is possible to obtain a large panel of colours not achievable via conventional alloying route. Here, we focus on one hybrid nanostructured material: Au-SiO2. The development of a new synthesis route enables us to obtain nanostructured micrometric powders that can then be pressed to obtain a bulk material. The resulting nanocomposites are characterized by means of energy-dispersive X-ray spectroscopy (EDX), fire assay, TEM and spectrophotocolorimetry. All these characterizations have shown that our composites exhibit a gold content superior to 75% by weight and have a much more vivid colour than classical coloured gold. The new composites are therefore deeply coloured 18-K materials. Keywords Colouredgold * 18-Kgold Goldnanocomposite * Gold nanoparticles * Surface plasmon resonance, Introduction Since the earliest time, due to humanity's attractiveness for gold, this noble metal had received a lot of attentions in particular from alchemists and metallurgists. Alchemists were looking for [...]

Published
2015
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12. Stress et développement de la polyarthrite rhumatoïde : étude cas-témoins sur le rôle des évènements de vie, l’évaluation du stress et les stratégies de coping

Author

Germain, Vincent and UB -, BU Carreire

Subjects
Polyarthrite rhumatoïde, Facteurs de risque, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Évènements de vie, Soutien social, Coping, Stress, Anxiété
Abstract

Objectives: to assess the stressful life events preceding the onset of symptoms in rheumatoid arthritis (RA), and to assess how RA patients evaluate and cope with stressors, together with the influence of gender and age. Methods: a case-control study was performed, comparing patients recently diagnosed with RA to age and gender-matched control subjects recently hospitalized for an unplanned surgical procedure not known to be influenced by stress. The Social Readjustment Rating Scale (SRRS) assessed the cumulative stress induced by stressful life events in the year preceding the onset of symptoms. Coping strategies, stress and anxiety symptoms were evaluated with Ways of Coping Checklist, Perceived Stress Scale, Multidimensional Health Locus of Control Scale, Social Support Questionnaire and State-Trait Anxiety Inventory. Results: seventy-six subjects were included in each group. The mean SRRS score was twice higher in cases compared to controls, with results more consistent in women than in men. The onset of RA symptoms was attributed to a stressful life event responsible for a psychological stress in 54.8% of cases, most often the death of a relative or friend. Scores of perceived stress and coping based on emotions were higher in RA patients. Females attributed more often the onset of RA symptoms to a stressful life event than males (70.2% versus 26.9%) and had a higher state anxiety score. Conclusion: stressful life events could contribute to the onset of RA symptoms, with marked specificities according to gender. Assessing stress and related adjustment strategies could help physicians to better manage the disease., Objectifs : étudier les évènements de vie précédant le début des symptômes de polyarthrite rhumatoïde (PR), la manière dont les patients évaluent le stress, les stratégies d’ajustement déployées pour y faire face (coping), et l’influence du sexe et de l’âge. Méthodes : une étude cas-témoins a été réalisée, comparant des patients atteints de PR avec un diagnostic récent, et des témoins appariés sur l’âge et le sexe opérés récemment d’une chirurgie non influencée par le stress. Le stress cumulé induit par les évènements de vie ayant eu lieu dans l’année précédant le début des symptômes était évalué par le SRRS (Social Readjustment Rating Scale : échelle de réajustement social). Les stratégies d’ajustement, le stress et les symptômes d’anxiété étaient évalués par les échelles suivantes : Ways of Coping Checklist (liste des stratégies de coping), Perceived Stress Scale (échelle de stress perçu), Multidimensional Health Locus of Control Scale (échelle multidimensionnelle de contrôle de la santé), Social Support Questionnaire (échelle de soutien social) et State-Trait Anxiety Inventory (inventaire d’anxiété-état). Résultats : soixante-seize sujets ont été inclus dans chaque groupe. Le score SRRS moyen était deux fois plus élevé dans le groupe des cas par rapport au groupe des témoins, avec des résultats plus prononcés chez les femmes que chez les hommes. Le début des symptômes de PR était attribué à un stress psychologique par 54,8% des patients, l’évènement le plus fréquemment rapporté était le décès d’un proche. Le score de stress perçu et les stratégies d’ajustement basées sur les émotions étaient plus importants chez les patients atteints de PR. Les femmes attribuaient plus souvent que les hommes le début des symptômes de PR à un évènement de vie stressant (70,2% versus 26,9%), et avaient un score d’anxiété-état plus élevé. Conclusion : les évènements de vie pourraient jouer un rôle dans le déclenchement des symptômes de PR, avec des spécificités notables en fonction du sexe. La prise en compte du stress et des stratégies d’ajustement dans la PR pourrait permettre de mieux prendre en charge la maladie.

Published
2018

14. Use of Biologics to Treat Relapsing and/or Refractory Eosinophilic Granulomatosis With Polyangiitis: Data From a European Collaborative Study.

Author

Canzian, Alice, Venhoff, Nils, Urban, Maria Letizia, Sartorelli, Silvia, Ruppert, Anne‐Marie, Groh, Matthieu, Girszyn, Nicolas, Taillé, Camille, Maurier, François, Cottin, Vincent, Moreuil, Claire, Germain, Vincent, Samson, Maxime, Jachiet, Marie, Denis, Laure, Rieu, Virginie, Smets, Perrine, Pugnet, Grégory, Deroux, Alban, and Durel, Cécile‐Audrey

Subjects
BIOTHERAPY, RETROSPECTIVE studies, ANTINEUTROPHIL cytoplasmic antibodies, TREATMENT effectiveness, CHURG-Strauss syndrome, DESCRIPTIVE statistics, DATA analysis software, PATIENT safety
Abstract

Objective: To describe the efficacy and safety of biologics for the treatment of eosinophilic granulomatosis with polyangiitis (EGPA). Methods: A retrospective European collaborative study was conducted in patients with EGPA who received treatment with biologics for refractory and/or relapsing disease. Results: Among the 147 patients with EGPA included in the study, 63 received rituximab (RTX), 51 received mepolizumab (MEPO), and 33 received omalizumab (OMA). At the time of inclusion, the median Birmingham Vasculitis Activity Score (BVAS) was 8.5 (interquartile range [IQR] 5–13) in the RTX group, while the median BVAS in the OMA group was 2 (IQR 1–4.5) and the median BVAS in the MEPO group was 2 (IQR 1–5). In patients receiving RTX, the median BVAS declined both at 6 months (median 1, IQR 0–4.5) and at 12 months (median 0, IQR 0–2), and the frequency of remission, partial response, treatment failure, and stopping treatment due to adverse events was 49%, 24%, 24%, and 3%, respectively. For the treatment of glucocorticoid (GC)–dependent asthma, patients who received MEPO had a much better GC‐sparing effect and overall response than did patients who received OMA. The frequency of remission, partial response, treatment failure, and stopping treatment due to adverse events was 15%, 33%, 48%, and 4%, respectively, in the OMA group and 78%, 10%, 8%, and 4%, respectively, in the MEPO group. Remission rates at 12 months were 76% and 82% among patients receiving MEPO at a doses of 100 mg and 300 mg, respectively. Conclusion: These results suggest that RTX could be effective in treating relapses of EGPA vasculitis. MEPO is highly effective with a good safety profile in patients with GC‐dependent asthma. Our data suggest that 100 mg MEPO monthly could be an acceptable dosage for first‐line therapy in selected instances of EGPA, recognizing, however, that this has not been compared to the validated dosage of 300 mg monthly. [ABSTRACT FROM AUTHOR]

Published
2021
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15. Full band all-sky search for periodic gravitational waves in the O1 LIGO data

Author

Abbott, Benjamin P., Abbott, Rich, Abbott, Thomas D., Acernese, Fausto, Ackley, Kendall, Adams, Carl, Adams, Thomas, Addesso, Paolo, Adhikari, Rana X., Adya, Vaishali B., Affeldt, Christoph, Afrough, Mohammad, Agarwal, Bhanu, Agathos, Michalis, Agatsuma, Kazuhiro, Aggarwal, Nancy, Aguiar, Odylio D., Aiello, Lorenzo, Ain, Anirban, Allen, Bruce, Allen, Gabrielle, Allocca, Annalisa, Altin, Paul A., Amato, Alex, Ananyeva, Alena, Anderson, Stuart B., Anderson, Warren G., Angelova, Svetoslava V., Antier, Sarah, Appert, Stephen, Arai, Koji, Araya, Melody C., Areeda, Joseph S., Arnaud, Nicolas, Ascenzi, Stefano, Ashton, Gregory, Ast, M., Aston, Stuart M., Astone, Pia, Atallah, Dany V., Aufmuth, Peter, Aulbert, Carsten, AultONeal, K., Austin, Corey, Avila-Alvarez, A., Babak, Stanislav, Bacon, Philippe, Bader, Maria K.M., Bae, Sangwook, Baker, Paul T., Baldaccini, Francesca, Ballardin, Giulio, Ballmer, Stefan W., Banagiri, Sharan, Barayoga, Juan C., Barclay, Sheena E., Barish, Barry C., Barker, David, Barkett, Kevin, Barone, Fabrizio, Barr, Bryan, Barsotti, Lisa, Barsuglia, Matteo, Barta, Daniel, Bartlett, Jeffrey, Bartos, Imre, Bassiri, Riccardo, Basti, Andrea, Batch, James C., Bawaj, Mateusz, Bayley, Joseph C., Bazzan, Marco, Bécsy, Bence, Beer, Christian, Bejger, Michal, Belahcene, Imene, Bell, Angus S., Berger, Beverly K., Bergmann, Gerald, Bero, John J., Berry, Christopher P.L., Bersanetti, Diego, Bertolini, Alessandro, Betzwieser, Joseph, Bhagwat, Swetha, Bhandare, Rohan, Bilenko, Igor A., Billingsley, Garilynn, Billman, Chris R., Birch, Jeremy, Birney, Ross, Birnholtz, Ofek, Biscans, Sebastien, Biscoveanu, Sylvia, Bisht, Aparna, Bitossi, Massimiliano, Biwer, Christopher, Bizouard, Marieanne A., Blackburn, J.K., Blackman, Jonathan, Blair, Carl D., Blair, David G., Blair, Ryan M., Bloemen, Steven, Bock, Oliver, Bode, Nina, Boer, Michel, Bogaert, Gilles, Bohe, Alejandro, Bondu, Francois, Bonilla, Edgard, Bonnand, Romain, Boom, Boris A., Bork, Rolf, Boschi, Valerio, Bose, Sukanta, Bossie, Ken, Bouffanais, Yann, Bozzi, Antonella, Bradaschia, Carlo, Brady, Patrick R., Branchesi, Marica, Brau, Jim E., Briant, Tristan, Brillet, Alain, Brinkmann, Marc, Brisson, Violette, Brockill, Patrick, Broida, Jacob E., Brooks, Aidan F., Brown, Duncan A., Brown, Daniel D., Brunett, Sharon, Buchanan, Christopher C., Buikema, Aaron, Bulik, Tomasz, Bulten, Henk J., Buonanno, Alessandra, Buskulic, Damir, Buy, Christelle, Byer, Robert L., Cabero, Miriam, Cadonati, Laura, Cagnoli, Giampietro, Cahillane, Craig, Calderón Bustillo, J., Callister, Thomas A., Calloni, Enrico, Camp, Jordan B., Canepa, Maurizio, Canizares, Priscilla, Cannon, Kipp C., Cao, H., Cao, Junwei, Capano, Collin D., Capocasa, Eleonora, Carbognani, Franco, Caride, Santiago, Carney, Matthew F., Casanueva Diaz, J., Casentini, Claudio, Caudill, Sarah, Cavaglià, Marco, Cavalier, Fabien, Cavalieri, Roberto, Cella, Giancarlo, Cepeda, Christian B., Cerdá-Durán, P., Cerretani, Giovanni, Cesarini, Elisabetta, Chamberlin, Sydney J., Chan, Manleong, Chao, Shiuh, Charlton, Philip, Chase, Eve, Chassande-Mottin, E., Chatterjee, Deep, Cheeseboro, Belinda D., Chen, H.Y., Chen, Xu, Chen, Yanbei, Cheng, H.-P., Chia, Hanyu Y., Chincarini, Andrea, Chiummo, Antonino, Chmiel, Theresa, Cho, Heesuk S., Cho, M., Chow, Jong H., Christensen, Nelson, Chu, Qi, Chua, Alvin J.K., Chua, Sheon, Chung, A.K.W., Chung, Shinkee, Ciani, Giacomo, Ciecielag, P., Ciolfi, Riccardo, Cirelli, Carissa E., Cirone, Alessio, Clara, Filiberto, Clark, James A., Clearwater, Patrick, Cleva, Frederic, Cocchieri, Camillo, Coccia, Eugenio, Cohadon, P.-F., Cohen, David, Colla, Alberto, Collette, Christophe G., Cominsky, Lynn R., Constancio, M., Conti, Livia, Cooper, Sam J., Corban, Paul, Corbitt, Thomas R., Cordero-Carrión, I., Corley, Kenneth R., Cornish, Neil, Corsi, Alessandra, Cortese, Stefano, Costa, Cesar A., Coughlin, Eric T., Coughlin, Michael W., Coughlin, Scott B., Coulon, J.-P., Countryman, Stefan T., Couvares, Peter, Covas, Pep B., Cowan, Erika E., Coward, David M., Cowart, Matthew J., Coyne, Dennis C., Coyne, Robert, Creighton, Jolien D.E., Creighton, Teviet D., Cripe, Jonathan, Crowder, Sgwynne G., Cullen, Torrey J., Cumming, Alan, Cunningham, Liam, Cuoco, Elena, Dal Canton, Tito, Dálya, Gergely, Danilishin, Stefan L., D'Antonio, S., Danzmann, Karsten, Dasgupta, Arnab, Da Silva Costa, C.F., Dattilo, Vincenzo, Dave, Ishant, Davier, Michel, Davis, Derek, Daw, Edward J., Day, Brian, De, Soumi, Debra, D., Degallaix, Jerome, De Laurentis, M., Deléglise, Samuel, Del Pozzo, W., Demos, Nicholas, Denker, Timo, Dent, Thomas, De Pietri, R., Dergachev, Vladimir, De Rosa, R., DeRosa, R.T., De Rossi, C., DeSalvo, R., de Varona, O., Devenson, Jan, Dhurandhar, Sanjeev, Díaz, Mario C., Di Fiore, L., Di Giovanni, M., Di Girolamo, T., Di Lieto, A., Di Pace, S., Di Palma, I., Di Renzo, F., Doctor, Zoheyr, Dolique, Vincent, Donovan, Fred, Dooley, Katherine L., Doravari, Suresh, Dorosh, O., Dorrington, Iain, Douglas, Rebecca, Dovale Álvarez, M., Downes, Thomas P., Drago, Marco, Dreissigacker, Christoph, Driggers, Jenne C., Du, Zhihui, Ducrot, Marine, Dupej, Peter, Dwyer, Sheila E., Edo, Tega B., Edwards, Matthew C., Effler, Anamaria, Eggenstein, H.-B., Ehrens, Phil, Eichholz, Johannes, Eikenberry, Stephen S., Eisenstein, Robert A., Essick, Reed C., Estevez, Dimitri, Etienne, Zachariah B., Etzel, Todd, Evans, Matthew, Evans, Tom M., Factourovich, Maxim, Fafone, Viviana, Fair, Hannah, Fairhurst, Stephen, Fan, Xilong, Farinon, Stefania, Farr, Benjamin, Farr, Will M., Fauchon-Jones, E.J., Favata, Marc, Fays, Maxime, Fee, Campbell, Fehrmann, Henning, Feicht, Jon, Fejer, Martin M., Fernandez-Galiana, A., Ferrante, Isidoro, Ferreira, Elvis C., Ferrini, Federico, Fidecaro, Francesco, Finstad, Daniel, Fiori, Irene, Fiorucci, Donatella, Fishbach, Maya, Fisher, Ryan P., Fitz-Axen, M., Flaminio, Raffaele, Fletcher, Mark, Fong, Heather, Font, J.A., Forsyth, Perry W.F., Forsyth, Steven S., Fournier, J.-D., Frasca, Sergio, Frasconi, Franco, Frei, Zsolt, Freise, Andreas, Frey, Raymond, Frey, Valentin, Fries, Eric M., Fritschel, Peter, Frolov, Valery V., Fulda, Paul, Fyffe, Michael, Gabbard, Hunter, Gadre, Bhooshan U., Gaebel, Sebastian M., Gair, Jonathan R., Gammaitoni, Luca, Ganija, Miftar R., Gaonkar, Sharad G., Garcia-Quiros, C., Garufi, Fabio, Gateley, B., Gaudio, Sergio, Gaur, Gurudatt, Gayathri, V., Gehrels, Neil, Gemme, Gianluca, Genin, Eric, Gennai, Alberto, George, Daniel, George, Jogy, Gergely, Laszlo, Germain, Vincent, Ghonge, Sudarshan, Ghosh, Abhirup, Ghosh, Archisman, Ghosh, Shaon, Giaime, Joe A., Giardina, K.D., Giazotto, Adalberto, Gill, Kiranjyot, Glover, Lamar, Goetz, Evan, Goetz, Ryan, Gomes, Sandra, Goncharov, Boris, González, Gabriela, Gonzalez Castro, J.M., Gopakumar, A., Gorodetsky, Michael L., Gossan, Sarah E., GOSSELIN, Matthieu, Gouaty, Romain, Grado, Aniello, Graef, Christian, Granata, Massimo, Grant, Alastair, Gras, Slawomir, Gray, Corey, Greco, Giuseppe, Green, Anna C., Gretarsson, Elizabeth M., Groot, Paul, Grote, Hartmut, Grunewald, Steffen, Gruning, Pierre, Guidi, Gianluca M., Guo, Xiangyu, Gupta, Anuradha, Gupta, Manojipr K., Gushwa, Kaitlin E., Gustafson, Eric K., Gustafson, R., Halim, O., Hall, Bernard R., Hall, Evan D., Hamilton, Eleanor Z., Hammond, Giles, Haney, Maria, Hanke, Manuela M., Hanks, Jonathan, Hanna, Chad, Hannam, Mark D., Hannuksela, Otto A., Hanson, Joe, Hardwick, Terra, Harms, Jan, Harry, Gregg M., Harry, Ian W., Hart, Martin J., Haster, C.-J., Haughian, Karen, Healy, James, Heidmann, Antoine, Heintze, Matthew C., Heitmann, Henrich, Hello, Patrice, Hemming, Gary, Hendry, Martin, Heng, I.S., Hennig, J., Heptonstall, Alastair W., Heurs, Michele, Hild, Stefan, Hinderer, Tanja, Hoak, Daniel, Hofman, David, Holt, Kathy, Holz, Daniel E., Hopkins, Paul, Horst, Christian, Hough, James, Houston, Ewan A., Howell, Eric J., Hreibi, A., Hu, Yiming M., Huerta, Eliu A., Huet, Dominique, Hughey, Brennan, Husa, Sascha, Huttner, Sabina H., Huynh-Dinh, T., Indik, Nathaniel, Inta, Ra, Intini, Giuseppe, Isa, Hafizah N., Isac, J.-M., Isi, Max, Iyer, Bala R., Izumi, Kiwamu, Jacqmin, Thibaut, Jani, Karan, Jaranowski, Piotr, Jawahar, Sharat, Jiménez-Forteza, F., Johnson, Warren W., Jones, D.I., Jones, Russell, Jonker, Reinier J.G., Ju, L., Junker, Jonas, Kalaghatgi, Chinmay V., Kalogera, Vassiliki, Kamai, Brittany, Kandhasamy, Shivaraj, Kang, Gungwon, Kanner, Jonah B., Kapadia, Shasvath J., Karki, Sudarshan, Karvinen, Kai S., Kasprzack, Marie, Katolik, Michael, Katsavounidis, Erik, Katzman, William, Kaufer, Steffen, Kawabe, Keita, Kéfélian, Fabien, Keitel, David, Kemball, Athol J., Kennedy, Ross, Kent, Christopher, Key, Joey S., Khalili, Farit Y., Khan, I., Khan, Sebastian, Khan, Ziauddin, Khazanov, Efim A., Kijbunchoo, Nutsinee, Kim, Chunglee, Kim, Jeongcho C., Kim, Kyungmin, Kim, Won, Kim, Whansun S., Kim, Y.-M., Kimbrell, Seth J., King, Eleanor J., King, Peter J., Kinley-Hanlon, M., Kirchhoff, Robin, Kissel, Jeffrey S., Kleybolte, Lisa, Klimenko, Sergei, Knowles, Tyler D., Koch, Philip, Koehlenbeck, Sina M., Koley, Soumen, Kondrashov, Veronica, Kontos, Antonios, Korobko, Mikhail, Korth, William Z., Kowalska, Izabela, Kozak, Dan B., Krämer, Christina, Kringel, Volker, Krishnan, Badri, Królak, Andrzej, Kuehn, Gerrit, Kumar, Prayush, Kumar, Rakesh, Kumar, Sumit, Kuo, L., Kutynia, Adam, Kwang, Shawn, Lackey, Benjamin D., Lai, K.H., Landry, Michael, Lang, Ryan N., Lange, Jacob, Lantz, Brian, Lanza, Robert K., Lartaux-Vollard, A., Lasky, Paul D., Laxen, Michael, Lazzarini, Albert, Lazzaro, Claudia, Leaci, Paola, Leavey, Sean, Lee, C.H., Lee, Hyunkyu K., Lee, H.M., Lee, Hyungwon W., Lee, K., Lehmann, Johannes, Lenon, Amber, Leonardi, Matteo, Leroy, Nicolas, Letendre, Nicolas, Levin, Yuri, Li, Tjonnie G.F., Linker, Seth D., Littenberg, Tyson B., Liu, J., Lo, R.K.L., Lockerbie, Nick A., London, Lionel T., Lord, Jaysin E., Lorenzini, Matteo, Loriette, Vincent, Lormand, Marc, Losurdo, Giovanni, Lough, James D., 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Jaranowski, Piotr, Jawahar, Sharat, Jiménez-Forteza, F., Johnson, Warren W., Jones, D.I., Jones, Russell, Jonker, Reinier J.G., Ju, L., Junker, Jonas, Kalaghatgi, Chinmay V., Kalogera, Vassiliki, Kamai, Brittany, Kandhasamy, Shivaraj, Kang, Gungwon, Kanner, Jonah B., Kapadia, Shasvath J., Karki, Sudarshan, Karvinen, Kai S., Kasprzack, Marie, Katolik, Michael, Katsavounidis, Erik, Katzman, William, Kaufer, Steffen, Kawabe, Keita, Kéfélian, Fabien, Keitel, David, Kemball, Athol J., Kennedy, Ross, Kent, Christopher, Key, Joey S., Khalili, Farit Y., Khan, I., Khan, Sebastian, Khan, Ziauddin, Khazanov, Efim A., Kijbunchoo, Nutsinee, Kim, Chunglee, Kim, Jeongcho C., Kim, Kyungmin, Kim, Won, Kim, Whansun S., Kim, Y.-M., Kimbrell, Seth J., King, Eleanor J., King, Peter J., Kinley-Hanlon, M., Kirchhoff, Robin, Kissel, Jeffrey S., Kleybolte, Lisa, Klimenko, Sergei, Knowles, Tyler D., Koch, Philip, Koehlenbeck, Sina M., Koley, Soumen, Kondrashov, Veronica, Kontos, Antonios, Korobko, Mikhail, Korth, William Z., Kowalska, Izabela, Kozak, Dan B., Krämer, Christina, Kringel, Volker, Krishnan, Badri, Królak, Andrzej, Kuehn, Gerrit, Kumar, Prayush, Kumar, Rakesh, Kumar, Sumit, Kuo, L., Kutynia, Adam, Kwang, Shawn, Lackey, Benjamin D., Lai, K.H., Landry, Michael, Lang, Ryan N., Lange, Jacob, Lantz, Brian, Lanza, Robert K., Lartaux-Vollard, A., Lasky, Paul D., Laxen, Michael, Lazzarini, Albert, Lazzaro, Claudia, Leaci, Paola, Leavey, Sean, Lee, C.H., Lee, Hyunkyu K., Lee, H.M., Lee, Hyungwon W., Lee, K., Lehmann, Johannes, Lenon, Amber, Leonardi, Matteo, Leroy, Nicolas, Letendre, Nicolas, Levin, Yuri, Li, Tjonnie G.F., Linker, Seth D., Littenberg, Tyson B., Liu, J., Lo, R.K.L., Lockerbie, Nick A., London, Lionel T., Lord, Jaysin E., Lorenzini, Matteo, Loriette, Vincent, Lormand, Marc, Losurdo, Giovanni, Lough, James D., Lovelace, Geoffrey, Lück, Harald, Lumaca, Diana, Lundgren, Andrew P., Lynch, Ryan, Ma, Y., Macas, Ronaldas, Macfoy, Sean, Machenschalk, Bernd, Macinnis, M., Macleod, Duncan M., Magaña Hernandez, I., Magaña-Sandoval, F., Magaña Zertuche, L., Magee, Ryan M., Majorana, Ettore, Maksimovic, Ivan, Man, N., Mandic, Vuk, Mangano, Valentina, Mansell, Georgia L., Manske, Michael, Mantovani, Maddalena, Marchesoni, Fabio, Marion, Frederique, Márka, Szabolcs, Márka, Zsuzsanna, Markakis, Charalampos, Markosyan, Ashot S., Markowitz, Aaron, Maros, E., Marquina, Antonio, Martelli, Filippo, Martellini, Lionel, Martin, Ian W., Martin, Rodica M., Martynov, Denis V., Mason, Ken, Massera, Elena, Masserot, Alain, Massinger, Thomas J., Masso-Reid, M., Mastrogiovanni, Simone, Matas, Andrew, Matichard, Fabrice, Matone, Luca, Mavalvala, Nergis, Mazumder, Nairwita, McCarthy, R., Mcclelland, D.E., Mccormick, S., McCuller, L., McGuire, S.C., Mcintyre, G., Mciver, J., McManus, David J., McNeill, L., McRae, T., McWilliams, S.T., Meacher, Duncan, Meadors, Grant D., Mehmet, Moritz, Meidam, Jeroen, Mejuto-Villa, E., Melatos, Andrew, Mendell, Gregory, Mercer, R.A., Merilh, Edmond L., Merzougui, Mourad, Meshkov, Syd, Messenger, Chris, Messick, Cody, Metzdorff, R., Meyers, Patrick M., Miao, Haixing, Michel, Christophe, Middleton, Hannah, Mikhailov, Eugeniy E., Milano, Leopoldo, Miller, Andrewlawrence L., Miller, Brandon B., Miller, John, Millhouse, Meg, Milovich-Goff, M.C., Minazzoli, Olivier, Minenkov, Yuri, Ming, Jing, Mishra, Chandra, Mitra, Sanjit, Mitrofanov, Valery P., Mitselmakher, Guenakh, Mittleman, Richard, Moffa, Donald, Moggi, Andrea, Mogushi, Kentaro, Mohan, Martin, Mohapatra, S.R.P., Montani, Matteo, Moore, Christopher J., Moraru, Dan, Moreno, Gerardo, Morriss, Sean R., Mours, Benoit, Mow-Lowry, C.M., Mueller, Guido, Muir, Alistair W., Mukherjee, Arunava, Mukherjee, Debnandini, Mukherjee, Soma, Mukund, Nikhil, Mullavey, Adam, Munch, Jesper, Muñiz, Erik A., Muratore, Martina, Murray, Peter G., Napier, Kate, Nardecchia, Ilaria, Naticchioni, Luca, Nayak, Rajesh K., Neilson, Joshua, Nelemans, Gijs, Nelson, Timothy J.N., Nery, Marina, Neunzert, Ansel, Nevin, Lydia, Newport, Jonathan M., Newton, Gavin, Ng, K.Y., Nguyen, Thanh T., Nichols, David, Nielsen, Alex B., Nissanke, Samaya, Nitz, Alex, Noack, Andreas, Nocera, Flavio, Nolting, David, North, Chris, Nuttall, Laura K., Oberling, Jason, O'Dea, G.D., Ogin, Greg H., Oh, John J., Oh, Sanghoon H., Ohme, Frank, Okada, Marcos A., Oliver, Miquel, Oppermann, Patrick, Oram, Richard J., O'Reilly, B., Ormiston, Rich, Ortega, Luis F., O'Shaughnessy, R., Ossokine, Serguei, Ottaway, David J., Overmier, Harry, Owen, Ben J., Pace, Alexander E., Page, Jessica, Page, Michael A., Pai, Archana, Pai, Siddhesh A., Palamos, Jordan R., Palashov, Oleg, Palomba, Cristiano, Pal-Singh, A., Pan, Howard, Pan, Huang-Wei, Pang, Belinda, Pang, P.T.H., Pankow, Chris, Pannarale, Francesco, Pant, Brijesh C., Paoletti, Federico, PAOLI, Andrea, Papa, Maria A., Parida, Abhishek, Parker, William, Pascucci, Daniela, Pasqualetti, Antonio, Passaquieti, Roberto, Passuello, Diego, Patil, M., Patricelli, Barbara, Pearlstone, Brynley L., Pedraza, Mike, Pedurand, Richard, Pekowsky, L., Pele, Arnaud, Penn, Steven, Perez, Carlos J., Perreca, Antonio, Perri, Leah M., Pfeiffer, Harald P., Phelps, Margot, Piccinni, Ornella J., Pichot, Mikhael, Piergiovanni, Francesco, Pierro, Vincenzo, Pillant, Gabriel, Pinard, Laurent, Pinto, Innocenzo M., Pirello, Marc, Pisarski, A., Pitkin, Matthew, Poe, Mark, Poggiani, Rosa, Popolizio, Pasquale, Porter, K., Post, Alexander, Powell, Jade, Prasad, Jayanti, Pratt, James W.W., Pratten, Geraint, Predoi, Valeriu, Prestegard, Tanner, Prijatelj, Mirko, Principe, Maria, Privitera, Stephen, Prodi, Giovanni A., Prokhorov, Leonid G., Puncken, Oliver, Punturo, Michele, Puppo, Paola, Pürrer, Michael, Qi, Hong, Quetschke, Volker, Quintero, Eric A., Quitzow-James, R., Raab, Fred J., Rabeling, David S., Radkins, Hugh, Raffai, Peter, Raja, Sendhil, Rajan, C., Rajbhandari, Binod, Rakhmanov, Malik, Ramirez, Karla E., Ramos-Buades, A., Rapagnani, Piero, Raymond, Vivien, Razzano, Massimiliano, Read, Jocelyn, Regimbau, Tania, Rei, Luca, Reid, Stuart, Reitze, David H., Ren, Wei, Reyes, Steven D., Ricci, Fulvio, Ricker, Paul M., Rieger, Sascha, Riles, Keith, Rizzo, Monica, Robertson, Norna A., Robie, Raymond, Robinet, Florent, Rocchi, Alessio, ROLLAND, Loic, Rollins, Jameson G., Roma, Vincent J., Romano, Rocco, Romel, Chandra L., Romie, Janeen H., Rosińska, Dorota, Ross, Michael P., Rowan, Sheila, Rüdiger, Albrecht, Ruggi, Paolo, Rutins, Guntis, Ryan, Kyle, Sachdev, Surabhi, Sadecki, Travis, Sadeghian, Laleh, Sakellariadou, Mairi, Salconi, Livio, Saleem, Muhammed, Salemi, Francesco, Samajdar, Anuradha, Sammut, Letizia, Sampson, Laura M., Sanchez, Eduardo J., Sanchez, Luis E., Sanchis-Gual, N., Sandberg, Vernon, Sanders, Jaclyn R., Sassolas, Benoit, Saulson, Peter R., Sauter, Orion, Savage, Richard L., Sawadsky, Andreas, Schale, Paul, Scheel, Mark, Scheuer, Jacob, Schmidt, Justus, Schmidt, Patricia, Schnabel, Roman, Schofield, Robert M.S., Schönbeck, Axel, Schreiber, Emil, Schuette, Dirk, Schulte, Bernd W., Schutz, Bernard F., Schwalbe, Sophia G., Scott, Jamie, Scott, Susan M., Seidel, E., Sellers, Danny, Sengupta, Anand S., Sentenac, Daniel, Sequino, Valeria, Sergeev, Alexander, Shaddock, Daniel A., Shaffer, Thomas J., Shah, Ankur A., Shahriar, M.S., Shaner, Morgan B., Shao, Lijing, Shapiro, Brett, Shawhan, Peter, Sheperd, Alec, Shoemaker, David H., Shoemaker, Deirdre M., Siellez, Karelle, Siemens, Xavier, Sieniawska, Magdalena, Sigg, Daniel, Silva, Allan D., Singer, Leo P., Singh, Avneet, Singhal, Akshat, Sintes, Alicia M., Slagmolen, Bram J.J., Smith, Bryan, Smith, Joshua R., Smith, Rory J.E., Somala, Surendranadh, Son, Edwin J., Sonnenberg, Jacob A., Sorazu, Borja, Sorrentino, Fiodor, Souradeep, Tarun, Spencer, Andrew P., Srivastava, Amit K., Staats, Kai, Staley, Alexan, Steinke, Michael, Steinlechner, Jessica, Steinlechner, Sebastian, Steinmeyer, Daniel, Stevenson, Simon P., Stone, Robert, Stops, David J., Strain, Ken A., Stratta, Giulia, Strigin, Sergey E., Strunk, A., Sturani, Riccardo, Stuver, Amber L., Summerscales, Tiffany Z., Sun, Ling, Sunil, S., Suresh, Jishnu, Sutton, Patrick J., Swinkels, Bas L., Szczepańczyk, Marek J., Tacca, Matteo, Tait, Simon C., Talbot, Colm, Talukder, Dipongkar, Tanner, David B., Tao, Duo, Tápai, Marton, Taracchini, Andrea, Tasson, Jay D., Taylor, Jordan A., Taylor, Robert, Tewari, Shivam V., Theeg, Thomas, Thies, Fabian, Thomas, E.G., Thomas, Michael, Thomas, Patrick, Thorne, Keith A., Thrane, Eric, Tiwari, Shubhanshu, Tiwari, Vaibhav, Tokmakov, Kirill V., Toland, Karl, Tonelli, Mauro, Tornasi, Zeno, Torres-Forné, A., Torrie, Calum I., Töyrä, Daniel, Travasso, Flavio, Traylor, Gary, Trinastic, Jonathan, Tringali, Maria C., Trozzo, Lucia, Tsang, K.W., Tse, Maggie, Tso, Rhondale, Tsukada, Leo, Tsuna, Daichi, Tuyenbayev, Darkhan, Ueno, Koh, Ugolini, Dennis, Unnikrishnan, Cs S., Urban, Alexander L., Usman, Samantha A., Vahlbruch, Henning, Vajente, Gabriele, Valdes, Guillermo, Van Bakel, N., van Beuzekom, Martin, Van Den Brand, J.F.J., Van Den Broeck, C., Vander-Hyde, D.C., van der Schaaf, L., van Heijningen, J.V., van Veggel, A.A., Vardaro, Marco, Varma, Vijay, Vass, Steve, Vasúth, Matyas, Vecchio, Alberto, Vedovato, Gabriele, Veitch, John, Veitch, Peter J., Venkateswara, Krishna, Venugopalan, Gautam, Verkindt, Didier, Vetrano, Flavio, Viceré, Andrea, Viets, Aaron D., Vinciguerra, Serena, Vine, David J., Vinet, J.-Y., Vitale, Salvatore, Vo, Thomas, Vocca, Helios, Vorvick, Cheryl, Vyatchanin, Sergey P., Wade, Andrew R., Wade, Leslie E., Wade, Madeline, Walet, Rob, Walker, Marissa, Wallace, Larry, Walsh, Sinead, Wang, Gang, Wang, Haoyu, Wang, Jonathan Z., Wang, Wenhui H., Wang, Yifan F., Ward, Robert L., Warner, Jim, Was, Michal, Watchi, Jennifer, Weaver, Betsy, Wei, L.-W., Weinert, Michael, Weinstein, Alan J., Weiss, Rainer, Wen, Linqing, Wessel, Erik K., Weßels, Peter, Westerweck, Julian, Westphal, Tobias, Wette, Karl, Whelan, John T., Whiting, Bernard F., Whittle, Chris, Wilken, D., Williams, Daniel, Williams, Roy D., Williamson, Andrew R., Willis, Joshua L., Willke, Benno, Wimmer, Maximilian H., Winkler, Walter, Wipf, Christopher C., Wittel, Holger, Woan, Graham, Woehler, Janis, Wofford, Jared, Wong, W.K., Worden, John, Wright, Jennifer L., Wu, David S., Wysocki, Daniel M., Xiao, Sophia, Yamamoto, Hiro, Yancey, Cregg C., Yang, Le, Yap, M.J., Yazback, Maher, Yu, Hang, Yu, Haocun, Yvert, Michel, Zadrożny, Adam, Zanolin, Michele, Zelenova, Tatiana, Zendri, J.-P., Zevin, Michael, Zhang, Liyuan, Zhang, Mi, Zhang, Teng, Zhang, Y.-H., Zhao, Chunnong, Zhou, Minchuan, Zhou, Zifan, Zhu, Sylvia J., Zhu, Xingjiang J., Zucker, Michael E., and Zweizig, J.

Abstract

We report on a new all-sky search for periodic gravitational waves in the frequency band 475-2000 Hz and with a frequency time derivative in the range of [-1.0,+0.1]×10-8 Hz/s. Potential signals could be produced by a nearby spinning and slightly nonaxisymmetric isolated neutron star in our Galaxy. This search uses the data from Advanced LIGO's first observational run O1. No gravitational-wave signals were observed, and upper limits were placed on their strengths. For completeness, results from the separately published low-frequency search 20-475 Hz are included as well. Our lowest upper limit on worst-case (linearly polarized) strain amplitude h0 is ∼4×10-25 near 170 Hz, while at the high end of our frequency range, we achieve a worst-case upper limit of 1.3×10-24. For a circularly polarized source (most favorable orientation), the smallest upper limit obtained is ∼1.5×10-25. © 2018 American Physical Society.

Published
2018

16. Role of stress in the development of rheumatoid arthritis: a case–control study.

Author

Germain, Vincent, Scherlinger, Marc, Barnetche, Thomas, Pichon, Clémence, Balageas, Alexandre, Lequen, Laurence, Shipley, Emilie, Foret, Jennifer, Dublanc, Stéphanie, Capuron, Lucile, Schaeverbeke, Thierry, and ACRONIM, the Fédération Hospitalo-Universitaire

Subjects
*ADAPTABILITY (Personality), *PSYCHOLOGICAL adaptation, *ANXIETY, *LIFE change events, *PSYCHOLOGICAL tests, *RHEUMATOID arthritis, *SOCIAL participation, *PSYCHOLOGICAL stress, *OPERATIVE surgery, *SOCIAL support, *CASE-control method, *PATIENTS' attitudes, *DESCRIPTIVE statistics, *SYMPTOMS
Abstract

Objectives The primary objective of this study was to assess the stressful life events preceding the onset of symptoms in RA. The secondary objectives were to assess how early RA patients perceive stress and cope with stressors. Methods A case–control study was performed, comparing patients recently diagnosed with RA to age- and gender-matched control subjects recently hospitalized for an unplanned surgical procedure not known to be influenced by stress. The Social Readjustment Rating Scale assessed the cumulative stress induced by stressful life events in the year preceding the onset of symptoms. Coping strategies, stress and anxiety symptoms were evaluated using validated psychological scales. Results Seventy-six subjects were included in each group. The mean Social Readjustment Rating Scale score was twice as high in cases compared with controls [respectively, 167.0 (172.5) vs 83.3 (124.4), P  < 0.001]. The association between cumulative stress and RA was statistically significant only in women, with a dose-dependent association between stress and RA. While female patients with RA attributed more often the onset of symptoms to a life event than female controls (70.2 vs 24.5%, P  < 0.001), no significant difference was found when comparing male RA patients with male controls (26.9 vs 18.5%, respectively, P  = 0.46). Increased perceived stress score (P  = 0.04) and coping based on emotions (P  = 0.001) were found in cases compared with controls. Conclusion Patients with early RA reported more life events in the year preceding the onset of symptoms than controls. Gender specificities were found with a significant association between cumulative stress and RA only in women. [ABSTRACT FROM AUTHOR]

Published
2021
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17. De l'étalonnage d'Advanced Virgo à la recherche d'ondes gravitationnelles émises par des coalescences de binaires compactes

Author

Germain, Vincent, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Université Grenoble Alpes, Didier Verkindt, and Loïc Rolland

Subjects
[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], Ondes gravitationnelles, SilenteC, Virgo, Calibration, Étalonnage, LIGO, MBTA, Gravitational waves
Abstract

The era of gravitational astronomy began with the first detection of a gravitational wave on September 14, 2015, by the LIGO-Virgo collaboration. The first detections come from coalescences of black holes with masses of a few tens of solar masses. The European detector Advanced Virgo restarted in 2017 to participate in the next detections of gravitational waves and to locate the astrophysical sources.This thesis deals with the different stages of the gravitational waves detection process: from the calibration of the Advanced Virgo detector to low-latency analysis of the LIGO-Virgo interferometer network data. First, the objectives, method and results of the detector calibration are described. This step is crucial for understanding the sensitivity of the detector and for reconstructing the amplitude of the gravitational wave. A new algorithm, SilenteC, developed during the thesis is then detailed: its objective is to identify the sources of non-stationary noises that limit the sensitivity of the analysis. Some transient noises are non-linear and SilenteC tries to identify this type of contribution. Finally, low-latency MBTA analysis for the detection of gravitational wave signals from compact binary coalescences is described. In particular, emphasis is put on the study of vetos making it possible to distinguish the astrophysical signals to be selected and the transient noises to be rejected as efficiently as possible.; L'ère de l'astronomie gravitationnelle a commencé avec la première détection d'une onde gravitationnelle le 14 septembre 2015, par la collaboration LIGO-Virgo. Les premières détections proviennent de coalescences de trous noirs de quelques dizaines de masses solaires. Le détecteur européen Advanced Virgo a redémarré en 2017 pour participer aux prochaines détections d'ondes gravitationnelles et localiser les sources astrophysiques.Cette thèse a pour sujet les différentes étapes du processus de détection des ondes gravitationnelles : de l'étalonnage du détecteur Advanced Virgo à l'analyse en temps réel des données du réseau d'interféromètres LIGO-Virgo. Dans un premier temps, les objectifs, la méthode et les résultats de l'étalonnage du détecteur Advanced Virgo sont décrits. Cette étape est cruciale pour comprendre la sensibilité du détecteur et pour reconstruire l'amplitude de l'onde gravitationnelle. Un nouvel algorithme, SilenteC, développé pendant la thèse est ensuite détaillé : son objectif est d'identifier les sources de bruits non-stationnaires qui limitent la sensibilité des analyses. Certains bruits transitoires interviennent de façon non-linéaire et SilenteC tente de repérer ce type de contribution. Enfin, l'analyse MBTA à faible latence pour la recherche des signaux d'ondes gravitationnelles issus de coalescences de binaires compactes est décrite. En particulier, l'accent est mis sur la caractérisation de vétos permettant de distinguer les signaux astrophysiques à sélectionner et les bruits transitoires à rejeter le plus efficacement possible.

Published
2017

18. From the calibration of Advanced Virgo to the search for gravitational waves emitted by compact binary coalescences

Author

Germain, Vincent, STAR, ABES, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Université Grenoble Alpes, Didier Verkindt, and Loïc Rolland

Subjects
[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], Ondes gravitationnelles, SilenteC, [PHYS.ASTR.CO] Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], Virgo, Calibration, Étalonnage, LIGO, MBTA, Gravitational waves
Abstract

The era of gravitational astronomy began with the first detection of a gravitational wave on September 14, 2015, by the LIGO-Virgo collaboration. The first detections come from coalescences of black holes with masses of a few tens of solar masses. The European detector Advanced Virgo restarted in 2017 to participate in the next detections of gravitational waves and to locate the astrophysical sources.This thesis deals with the different stages of the gravitational waves detection process: from the calibration of the Advanced Virgo detector to low-latency analysis of the LIGO-Virgo interferometer network data. First, the objectives, method and results of the detector calibration are described. This step is crucial for understanding the sensitivity of the detector and for reconstructing the amplitude of the gravitational wave. A new algorithm, SilenteC, developed during the thesis is then detailed: its objective is to identify the sources of non-stationary noises that limit the sensitivity of the analysis. Some transient noises are non-linear and SilenteC tries to identify this type of contribution. Finally, low-latency MBTA analysis for the detection of gravitational wave signals from compact binary coalescences is described. In particular, emphasis is put on the study of vetos making it possible to distinguish the astrophysical signals to be selected and the transient noises to be rejected as efficiently as possible., L'ère de l'astronomie gravitationnelle a commencé avec la première détection d'une onde gravitationnelle le 14 septembre 2015, par la collaboration LIGO-Virgo. Les premières détections proviennent de coalescences de trous noirs de quelques dizaines de masses solaires. Le détecteur européen Advanced Virgo a redémarré en 2017 pour participer aux prochaines détections d'ondes gravitationnelles et localiser les sources astrophysiques.Cette thèse a pour sujet les différentes étapes du processus de détection des ondes gravitationnelles : de l'étalonnage du détecteur Advanced Virgo à l'analyse en temps réel des données du réseau d'interféromètres LIGO-Virgo. Dans un premier temps, les objectifs, la méthode et les résultats de l'étalonnage du détecteur Advanced Virgo sont décrits. Cette étape est cruciale pour comprendre la sensibilité du détecteur et pour reconstruire l'amplitude de l'onde gravitationnelle. Un nouvel algorithme, SilenteC, développé pendant la thèse est ensuite détaillé : son objectif est d'identifier les sources de bruits non-stationnaires qui limitent la sensibilité des analyses. Certains bruits transitoires interviennent de façon non-linéaire et SilenteC tente de repérer ce type de contribution. Enfin, l'analyse MBTA à faible latence pour la recherche des signaux d'ondes gravitationnelles issus de coalescences de binaires compactes est décrite. En particulier, l'accent est mis sur la caractérisation de vétos permettant de distinguer les signaux astrophysiques à sélectionner et les bruits transitoires à rejeter le plus efficacement possible.

Published
2017

20. Potential Threats of UAS Swarms and the Countermeasure’s Need

Author

Beaudoin, Laurent, Gademer, Antoine, Avanthey, Loïca, Germain, Vincent, Vittori, Vincent, Ecole Supérieure d'Informatique Electronique Automatique [Paris] (ESIEA), and AVANTHEY, Loïca

Subjects
[MATH.MATH-IT] Mathematics [math]/Information Theory [math.IT], [SPI.AUTO] Engineering Sciences [physics]/Automatic, [MATH.MATH-IT]Mathematics [math]/Information Theory [math.IT], terrorism, swarms, countermeasure, unmanned aerial system, [SPI.AUTO]Engineering Sciences [physics]/Automatic
Abstract

International audience; The rising capabilities and growing accessibility of recent Unmanned Aerial Systems (UAS) widen the risks of success of a terrorists attack through the current aerial defence systems. We will examine first the complexity of the threats from a single unmanned vehicle, to a team of unmanned vehicles and finally to a swarm of unmanned vehicles (and any other association of these three combinations). Then, from an operational point of view, we will see that early detection of danger - a critical stage in the development of counter-attacks - has become very difficult because small unmanned vehicles like UASs precisely possess the ability to take off directly within the sphere of attack. The next stage, equally critical, consists in elaborating the response that best fits the attack. We distinguish three general categories of active and passive countermeasures: destruction, incapacitation and jamming of the enemy UASs. We will then study several possible countermeasures appropriate to the type of attack (enemy’s formation: isolated drone, team, swarm; weapon type: bomb, kamikaze, bacteriological etc.). We first present countermeasures that are rather conventional (they usually come from air defense systems) and others specific to the UAS case. We will finish by a case study in which we will tackle the use of simplified physical models for calculating positions in real time in an optimized way in a UAS swarm under constraints.

Published
2011

21. Membranes inorganiques dans le quaternaire Si-Zr-C-N pour la purification de l’hydrogène

Author

Chareyre, Laeticia, Rouessac, Vincent, Germain, Vincent, Julbe, Anne, Louradour, Eric, Delbianco, N., Bernard, Samuel, Miele, Philippe, Cornu, David, Institut Européen des membranes (IEM), Université Montpellier 2 - Sciences et Techniques (UM2)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Ecole Supérieure d'Informatique Electronique Automatique [Paris] (ESIEA), and Bernard, Samuel

Subjects
[CHIM] Chemical Sciences, [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2010

30. Electrostatic interactions of colloidal particles in nonpolar solvents: role of surface chemistry and charge control agents.

Author

Sainis SK, Germain V, Mejean CO, and Dufresne ER

Subjects
Aerosols chemistry, Optical Tweezers, Particle Size, Solvents chemistry, Static Electricity, Surface Properties, Thermodynamics, Alkanes chemistry, Colloids chemistry, Polymers chemistry, Polymethyl Methacrylate chemistry, Polystyrenes chemistry, Succinates chemistry, Succinimides chemistry
Abstract

We study the electrostatic and hydrodynamic interactions of colloidal particles in nonpolar solvents. Using blinking optical tweezers, we can extract the screening length, kappa-1, the effective surface potential, |ezeta*|, and the hydrodynamic radius, ah, in a single measurement. We apply this technique to suspensions of polystyrene and poly(methyl methacrylate) particles in hexadecane with soluble charge control agents, aerosol sodium di-2-ethylhexylsulfosuccinate (AOT) and polyisobutylene succinimide (OLOA-1200). We find that the electrostatic interactions of these particles depend sensitively on surface composition as well as on the concentration and chemistry of the charge control agent.

Published
2008
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