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16 results on '"Gerard, Michele"'

2. Clinical Management of Argentine Hemorrhagic Fever using Ribavirin and Favipiravir, Belgium, 2020

Author

Veliziotis, Ioannis, Roman, Alain, Martiny, Delphine, Schuldt, Gerlind, Claus, Marc, Dauby, Nicolas, Van den Wjngaert, Sigi, Martin, Charlotte, Nasreddine, Rakan, Perandones, Claudia, Mahieu, Romain, Swaan, Corien, Van Praet, Serge, Konopnicki, Deborah, Morales, Maria A., Malvy, Denis, Stevens, Etienne, Dechamps, Philippe, Vlieghe, Erika, Vandenberg, Olivier, Gunther, Stephan, and Gerard, Michele

Subjects
Vaccines, Lassa fever, Hemorrhagic fevers, Tazobactam, Levetiracetam, Ribavirin, Meropenem, Company business management, Health
Abstract

Argentine hemorrhagic fever (AHF) is a severe hemorrhagic fever caused by a New World arenavirus, Junin virus (JUNV), which was discovered in 1958 (1). The virus reservoir consists of rodents [...]

Published
2020
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3. Risk of Misinterpretation of Ebola Virus PCR Results After rVSV ZEBOV-GP Vaccination

Author

Cnops, Lieselotte, Gerard, Michèle, Vandenberg, Olivier, Van den Wijngaert, Sigi, Heyndrickx, Leo, Willems, Elisabeth, Demeulemeester, Kathy, De Clerck, Hilde, Dediste, Anne, Callens, Steven, De Munter, Paul, Vlieghe, Erika, Bottieau, Emmanuel, Wuillaume, Francoise, Van Esbroeck, Marjan, and Ariën, Kevin K.

Published
2015

9. Point prevalence survey of antimicrobial use and healthcare-associated infections in Belgian acute care hospitals : results of the Global-PPS and ECDC-PPS 2017

Author

Vandael, Eline, Latour, Katrien, Goossens, Herman, Magerman, Koen, Drapier, Nico, Catry, Boudewijn, Versporten, Ann, Andre, Marie, Aouachria, Samy, Aoun, Mickael, Bafort, Kristof, Bartholomeus, Sofie, Blumental, Sophie, Bothy, Anais, Brands, Christiane, Brassinne, Laetitia, Briquet, Caroline, Cartuyvels, Reinoud, Ceyssens, Clara, Cooreman, Sarah, Decleire, Pierre-Yves, Declercq, Philippe, De Cooman, Liesbeth, De Cuyper, Inge, Degraeve, Dirk, Delaere, Benedicte, Delvallee, Melanie, Desmedt, Marjoleine, Diaz, Victoria, Dragos, Ilisei, Dugernier, Thierry, Elsen, Elodie, Filippin, Lorenzo, Firre, Eric, Frans, Johan, Gabriels, Patrick, Gadisseux, Philippe, Gerard, Michele, Glibert, Bart, Goegebuer, Truus, Gonissen, Viviane, Harrouk, Antoine, Holemans, Xavier, Honore, Aline, Ide, Louis, Jansens, Hilde, Kidd, Francois, Koch, Annelies, Konopnicki, Deborah, Lefevre, Philippe, Lespagnard, Marc, Lorent, Sophie, Maillart, Evelyne, Mallet, Martine, Markowicz, Samuel, Mathieu, Delphine, Michel, Philippe, Noirhomme, Severine, Papin, Pauline, Piette, Anne, Pollet, Leen, Rossi, Camelia, Schatt, Patricia, Sermijn, Erica, Sterckx, Astrid, Steyaert, Sophia, Swinnen, Walter, Teixeira Lopes, Liliana, Thoelen, Inge, Turkova, Myriam, Van den Abeele, Anne-Marie, Van den Berg, Valerie, Van der beek, Danielle, Vanderper, Vanessa, Vandevelde, Marc, Vandewal, Wouter, Van Herendael, Bruno, Vanheule, Geert, Van Hoecke, Frederik, Van Kerkhoven, Dana, Van Liedekerke, Ann, Vanneste, Lorenz, Vekemans, Marc, Vercheval, Christelle, Verhamme, Katia, Verniest, Thessa, Westerlinck, Veerle, Wybo, Ingrid, Belgian Point Prevalence Survey, Swinnen, Walter/0000-0001-5387-149X, and Vriendenkring VUB

Subjects
Male, Antibiotics, Drug resistance, Antimicrobial Stewardship, Medical microbiology, Drug Utilization Review, Belgium, Risk Factors, Acute care, Antimicrobial consumption, Prevalence, Medicine, Pharmacology (medical), Pharmacology & Pharmacy, Point prevalence survey, Child, health care economics and organizations, Public, Environmental & Occupational Health, Medicine(all), Aged, 80 and over, Cross Infection, Pharmacology. Therapy, Middle Aged, Antimicrobial, Anti-Bacterial Agents, Infectious Diseases, Child, Preschool, Female, Life Sciences & Biomedicine, Microbiology (medical), Adult, medicine.medical_specialty, Adolescent, medicine.drug_class, education, Healthcare-associated infections, Microbiology, lcsh:Infectious and parasitic diseases, Young Adult, Internal medicine, Humans, lcsh:RC109-216, Medical prescription, Biology, Aged, Science & Technology, business.industry, Research, Public Health, Environmental and Occupational Health, Infant, Newborn, Infant, Généralités, medicine.disease, Health Surveys, Confidence interval, Pneumonia, Acute care hospitals, Human medicine, business
Abstract

Background: The point prevalence survey of healthcare-associated infections (HAIs) and antimicrobial use organized by the European Centre for Disease Prevention and Control (ECDC-PPS) and the Global Point Prevalence Survey of antimicrobial consumption (Global-PPS) were simultaneously performed in Belgian acute care hospitals in 2017. Methods: Belgian acute care hospitals were invited to participate in either the ECDC or Global-PPS. Hospital/ward/patient-level data were collected between September-December 2017. All patients present in the wards at 8 a.m. on the day of the PPS were included. The data of the ECDC and Global-PPS on antimicrobial consumption were pooled. Detailed data on HAIs were analysed for ECDC-PPS. Results: Overall, 110 Belgian acute care hospital sites participated in the ECDC and Global-PPS (countrywide participation rate: 81.4%, 28,007 patients). Overall, a crude prevalence of patients with at least one antimicrobial of 27.1% (95% confidence interval (CI) 26.5-27.6%) was found. The most frequently reported indications were pneumonia (23.2%), urinary tract infections (15.2%) and skin and soft tissue infections (11.9%). The reason for antimicrobial use was recorded for 81.9% of the prescriptions, a stop/review date for 40.8% and compliance with local antibiotic guidelines for 76.6%. In the ECDC-PPS, the crude prevalence of patients with at least one HAI was 7.3% (95%CI 6.8-7.7%). Most frequently reported HAIs were pneumonia (21.6%) and urinary tract infections (21.3%). Conclusions: HAI and antimicrobial use prevalence remained stable in comparison with the previous PPS (7.1% and 27.4% in 2011 and 2015, respectively). Belgian hospitals should be further stimulated to set local targets to improve antibiotic prescribing and reduce HAI., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2020

16. Molecular Epidemiological Study of NosocomialEnterobacter aerogenesIsolates in a Belgian Hospital

Author

Jalaluddin, Sheikh, Devaster, Jeanne-Marie, Scheen, Robert, Gerard, Michele, and Butzler, Jean-Paul

Abstract

ABSTRACTIn 1995, the rate of isolation of Enterobacter aerogenesin the Saint-Pierre University Hospital in Brussels, Belgium, was higher than that in the preceding years. A total of 45 nosocomial E. aerogenesstrains were collected from 33 patients of different units during that year, and they were isolated from 19 respiratory specimens, 13 pus specimens, 7 blood specimens, 4 urinary specimens, 1 catheter specimen, and 1 heparin vial. The strains were analyzed to determine their epidemiological relatedness and were characterized by their antibiotic resistance pattern determination, plasmid profiling, and genomic fingerprinting by macrorestriction analysis with pulsed-field gel electrophoresis (PFGE). The majority of the strains (82%) were multiply resistant to different commonly used antibiotics. Two major plasmid profiles were found: most strains (64%) harbored two plasmids of different sizes, whereas the others (20%) contained a single plasmid. PFGE with SpeI and/orXbaI restriction enzymes revealed that a single clone (80%) was responsible for causing infections or colonizations throughout the year, and this result was concordant with those obtained by plasmid profiling, with slight variations. By comparing the results of these three methods, PFGE and plasmid profiling were found to be the techniques best suited for investigating the epidemiological relatedness of E. aerogenesstrains, and they are therefore proposed as useful tools for the investigation of nosocomial outbreaks caused by this organism.

Published
1998
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