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111 results on '"Geraci, J. R."'

10. A histological assessment of damage in rainbow trout, <em>Salmo gairdneri</em> Richardson, fed rations containing erythromycin.

Author

Hicks, B. D. and Geraci, J. R.

Subjects
*RAINBOW trout, *ERYTHROMYCIN, *EPITHELIAL cells, *KIDNEY tubules, *LYSOSOMES, *APPETITE loss, *BACTERIAL diseases, *KIDNEY diseases
Abstract

Rainbow trout fed prepared rations containing therapeutic levels of erythromycin (110 mg/kg daily) developed lesions in epithelial cells of the first proximal segment of the nephron. Pathological changes which developed within 24 h were characteristic of congestive overloading of lysosomes. Treated fish became anorexic within 2-3 weeks. Affected epithelial cells of fish after 14 days of anorexia contained residual bodies in an otherwise normal appearing cytoplasm. Cell injury was reversible. Since the onset of anorexia corresponded with the completion of the recommended treatment period and damaged cells repair rapidly, erythromycin should nevertheless be retained as the treatment of choice for bacterial kidney disease. [ABSTRACT FROM AUTHOR]

Published
1984
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12. Dolphin pox: a skin disease of cetaceans

Author

Geraci, J R, Hicks, B D, and St Aubin, D J

Subjects
Male, Dolphins, Poxviridae, Animals, Poxviridae Infections, Skin Diseases, Infectious, human activities, Research Article, Skin
Abstract

Poxvirus has been identified morphologically from skin lesions in captive and free-ranging bottlenosed dolphins, Tursiops truncatus and a stranded Atlantic white-sided dolphin, Lagenorhynchus acutus. The lesions, commonly referred to as ring or pinhole lesions, appear as solitary or coalesced circular grey blemishes. Advanced ring lesions may take the form of black punctiform stippled patterns known as "tattoo". Histologically, the stratum externum is thickened, and there is ballooning degeneration and eosinophilic intractyoplasmic inclusions in the stratum intermedium. These includions contain virus particles which exhibit typical poxvirus morphology. Stress, environmental conditions and general health appear to play a major role in the clinical manifestation of dolphin pox.

Published
1979

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