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3. Colistin Therapy, Survival and Renal Replacement Therapy in Burn Patients: A 10-Year Single-Center Cohort Study

Author

Mariano F, Malvasio V, Risso D, Depetris N, Pensa A, Fucale G, Gennari F, Biancone L, and Stella M

Subjects
colistin - burns - acute kidney injury - mdrgn infection - crrt - clinical outcome, Medicine (General), R5-920
Abstract

Filippo Mariano,1,2,&ast; Valeria Malvasio,3,4,&ast; Daniela Risso,3 Nadia Depetris,5 Anna Pensa,3,6 Giacomo Fucale,7 Fabrizio Gennari,4 Luigi Biancone,1,2 Maurizio Stella3 1Nephrology, Dialysis and Transplantation U, Department of General and Specialized Medicine, City of Science and Health, CTO Hospital, Torino, Italy; 2Department of Medical Sciences, University of Torino, Torino, Italy; 3Burn Center and Plastic Surgery, Department of General and Specialized Surgery, City of Science and Health, CTO Hospital, Torino, Italy; 4Department of Pediatric General Surgery, City of Science and Health, Regina Margherita Children’s Hospital, Torino, Italy; 5Anesthesia and Intensive Care 3, Department of Anesthesia and Intensive Care, City of Science and Health, CTO Hospital, Torino, Italy; 6Department of Surgical Sciences, University of Torino, Torino, Italy; 7Laboratory of Microbiology and Virology, City of Science and Health, Molinette Hospital, Torino, Italy&ast;These authors contributed equally to this workCorrespondence: Filippo Mariano, Nephrology, Dialysis and Transplantation U, AOU City of Science and Health, CTO Hospital, Via G. Zuretti 29, Torino, 10126, Italy, Tel +39-011-6933-674, Fax +39-011-6933-672, Email filippo.mariano@unito.itPurpose: Colistin is still a therapeutic cornerstone against multidrug-resistant gram-negative bacteria (MDRGN), mostly when other antibiotics do not gain adequate activity on these strains. In the present study, we evaluated in a cohort of burn patients the relationship between colistin therapy, survival and requirement of renal replacement therapy (CRRT).Patients and Methods: Retrospective study of 133 burn patients treated with iv colistimethate sodium (loading dose 9.0 × 106 IU, maintenance dose 4.5 × 106 IU BID) and 35 treated with other antibiotics for MDRGN infection including Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae between January 2008 and December 2017. Multivariate analysis with logistic regression was used to determine the effect of the predictors such as age, total body surface area (TBSA), third-degree burn areas, Revised Baux score, Charlson comorbidity score, length of stay, colistin dose and duration of treatment, mechanical ventilation, and need of CRRT on in-hospital mortality. To investigate the relationship between colistin and renal function, we focused on survivor patients as the completion of the therapeutic course of colistin represented the basic requirement to analyze its impact on the kidney.Results: Out of 133 colistin- and 35 other antibiotics-treated patients, 83 (62.4%) and 31 (88.6%) survived, and 53 (39.8%) and 3 (9.7%) required CRRT, respectively. The severity of burns, as well as CRRT requirement and mortality, was significantly higher in colistin-treated patients than in other antibiotics-treated patients. Age and TBSA% were the significant predictors of mortality. Out of 83 colistin-treated survivors, 19 (22.9%) required CRRT (9 before and 10 after the start of colistin), and 64 (77.1%) had a normal renal function. No difference about the colistin dose and baseline characteristics, but the revised Baux score was found between the 9 patients requiring CRRT before the colistin course and the 10 patients after. Similarly, among the 64 patients not undergoing CRRT, no difference was found between the patients treated with the cumulative dose of colistin < 99.0 × 106 IU (n = 33, median daily dose of 4.0 × 106 IU) and > 99.0 × 106 IU (n = 31, median daily dose of 9.0 × 106 IU) about the baseline characteristics and the daily median plasma creatinine over 24 days of therapy.Conclusion: Colistin therapy was associated with more severe burns, mortality, and CRRT requirement. A short course therapy, at appropriate cumulative dosage, can lead to clinical success without a significant association with severe renal impairment.Keywords: colistin, burns, acute kidney injury, MDRGN infection, CRRT, clinical outcome

Published
2022

10. Quantitative Trait Loci Mapping and Identification of Candidate Genes Linked to Fruit Acidity in Apricot (

Author

Dondini L., Domenichini C., Dong Y., Gennari F., Bassi D., Foschi S., Lama M., Adami M., De Franceschi P., Cervellati C., Bergonzoni L., Alessandri S., Tartarini S., and Dondini L., Domenichini C., Dong Y., Gennari F., Bassi D., Foschi S., Lama M., Adami M., De Franceschi P., Cervellati C., Bergonzoni L., Alessandri S., Tartarini S.

Subjects
fruit pH, malate, citrate, quinate, fruit quality, food and beverages
Abstract

Apricot breeding programs could be strongly improved by the availability of molecular markers linked to the main fruit quality traits. Fruit acidity is one of the key factors in consumer acceptance, but despite its importance, the molecular bases of this trait are still poorly understood. In order to increase the genetic knowledge on the fruit acidity, an F1 apricot population (‘Lito’ ‘BO81604311’) has been phenotyped for titratable acidity and juice pH for the three following years. In addition, the contents of the main organic acids of the juice (malate, citrate, and quinate) were also evaluated. A Gaussian distribution was observed for most of the traits in this progeny, confirming their quantitative inheritance. An available simple sequence repeat (SSR)- based molecular map, implemented with new markers in specific genomic regions, was used to perform a quantitative trait loci (QTL) analysis. The molecular map was also anchored to the recently published apricot genome sequence of ‘Stella.’ Several major QTLs linked to fruit acidity-related traits have been identified both in the ‘Lito’ (no. 21) and ‘BO81604311’ (no. 13), distributed in five linkage groups (LG 4, 5, 6, 7, and 8). Some of these QTLs show good stability between years and their linked markers were used to identify candidate genes in specific QTLs genomic regions.

Published
2021

11. Contributors

Author

Agarwal, Rajiv, primary, Aghemo, Alessio, additional, Al-Lawati, Ali, additional, Allon, Michael, additional, Andrews, Walter S., additional, Annunziato, Rachel A., additional, Araya, Carlos E., additional, Asif, Arif, additional, Ayoob, Rose M., additional, Baracco, Rossana, additional, Bargman, Joanne, additional, Beathard, Gerald A., additional, Bellasi, Antonio, additional, Bennett, William M., additional, Berns, Jeffrey S., additional, Bieber, Scott, additional, Block, Geoffrey A., additional, Boccardo, Paola, additional, Brookens, Andrew, additional, Brophy, Patrick D., additional, Brunelli, Steven, additional, Burkart, John M., additional, Bushinsky, David, additional, Campese, Vito M., additional, Cepeda, Celina Denise, additional, Chadha, Vimal, additional, Chan, Christopher T., additional, Chand, Deepa H., additional, Chang, Anthony, additional, Chang, Tara I., additional, Charytan, Chaim, additional, Chen, Joline L.T., additional, Chen, Wei, additional, Claudio, Ronco, additional, Collins, Allan J., additional, Crabtree, John H., additional, Crowley, Lisa E., additional, Cukor, Daniel, additional, Davies, Simon J., additional, Deger, Serpil Muge, additional, Depner, Thomas A., additional, Diaz-Buxo, Jose A., additional, Dinwiddie, Lesley C., additional, Dukkipati, Ramanath, additional, Duncan, Sarah E., additional, Fabrizi, Fabrizio, additional, Fischbach, Michel, additional, Fishbane, Steven, additional, Fissell, William Henry, additional, Foster, Bethany, additional, Galbusera, Miriam, additional, Gennari, F. John, additional, Ghannoum, Marc, additional, Ghazan-Shahi, Sassan, additional, Goldstein, Stuart L., additional, Gotch, Frank A., additional, Greenwood, Sharlene, additional, Haffner, Dieter, additional, Himmele, Rainer, additional, Holland, Janet E., additional, Holley, Jean L., additional, Holmes, Clifford, additional, Hooper, Stephen R., additional, Hothi, Daljit K., additional, Hou, Susan, additional, Hutchison, Alastair J., additional, Ikizler, T. Alp, additional, Jaber, Bertrand L., additional, Jassal, Sarbjit Vanita, additional, Kalantar-Zadeh, Kamyar, additional, Koh Jee Kam, Timothy, additional, Kaplan, Mark, additional, Kathuria, Pranay, additional, Kaufman, Jeffrey L., additional, Khanna, Ramesh, additional, Khosla, Neenoo, additional, Kimmel, Paul L., additional, Kooienga, Laura, additional, Koufaki, Pelagia, additional, Kovalik, Eugene C., additional, Kreuzer, Martin, additional, Krishna, Vinay Narasimha, additional, Krishnan, Mahesh, additional, Kuhlmann, Martin K., additional, Lakdawala, Ravi S., additional, Lam, Danica, additional, Lambie, Mark, additional, Lok, Charmaine E., additional, Mahan, John D., additional, Manley, Harold J., additional, Martin, Kevin J., additional, Martin, Paul, additional, Mathur, Piyush, additional, McIntyre, Christopher W., additional, Mehrotra, Rajnish, additional, Mehta, Ravindra L., additional, Mescia, Federica, additional, Mitsnefes, Mark M., additional, Modi, Gopesh K., additional, Moist, Louise, additional, Moodalbail, Divya G., additional, Moritz, Michael L., additional, Moss, Alvin H., additional, Nalesso, Federico, additional, Nessim, Sharon J., additional, Neul, Shari K., additional, Nissenson, Allen R., additional, Olyaei, Ali J., additional, Ortiz-Melo, David I., additional, Palmer, Biff F., additional, Palmer, Suetonia C., additional, Parfrey, Patrick S., additional, Pencille, Melissa, additional, Pham, Phuong-Chi T., additional, Pham, Phuong-Thu T., additional, Pittard, Joanne D., additional, Remuzzi, Giuseppe, additional, Rhee, Connie M., additional, Rigatto, Claudio, additional, Roberts, Darren M., additional, Rodriguez, Rudolph A., additional, Ronco, Claudio, additional, Rosenthal, Deborah, additional, Sadler, John H., additional, Satko, Scott G., additional, Schaefer, Franz, additional, Selewski, David T., additional, Sethna, Christine B., additional, Shah, Hitesh H., additional, Shapiro, Ron, additional, Sherman, Richard A., additional, Shroff, Rukshana, additional, Singer, Pamela, additional, Smith, Jodi M., additional, Somers, Michael J.G., additional, Soo, Euan, additional, Spinowitz, Bruce S., additional, Stein, Deborah, additional, Stivelman, John C., additional, Strippoli, Giovanni F.M., additional, Stronach, Lynsey, additional, Susantitaphong, Paweena, additional, Szeto, Cheuk-Chun, additional, Thomas, Rebecca, additional, Tolwani, Ashita, additional, Traum, Avram Z., additional, Vachharajani, Tushar, additional, Valentini, Rudolph P., additional, VanDeVoorde, René G., additional, Vardhan, Anand, additional, Vo, Thanh-Mai, additional, Wagner, Thor A., additional, Warady, Bradley A., additional, Wesseling-Perry, Katherine, additional, Westcott, Spencer, additional, Wetmore, James B., additional, Wille, Keith, additional, Williams, Mark E., additional, Wish, Jay B., additional, Yousaf, Farhanah, additional, Zaloszyc, Ariane, additional, and Zaritsky, Joshua, additional

Published
2017
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13. Risk Management in Circular Economy Strategies

Author

Salvioni, D. M., Gennari, F., and Cassano, R.

Subjects
Risk management, Sustainability, Strategy, Circular Economy, Circular Economy, Risk management, Strategy, Sustainability
Published
2022

22. BULLOUS PILOMATRIXOMA

Author

Garofalo, S., Guana, R., Scottoni, F., Cortese, M. G., Cerrina, A., Linari, A., Carli, D., Ferrero, G. B., and Gennari, F.

Subjects
Child, Neoplasms, Pilomatrixoma, Skin
Published
2020

23. Responsiveness

Author

Gennari, F

Subjects
Responsible Government, Social Responsibility, Responsibility, Accountability, Responsible Governance, Stakeholder Engagement
Published
2020

26. Mapping of the apple scab-resistance gene Vb

Author

Erdin, N., Tartarini, S., Broggini, G.A.L., Gennari, F., Sansavini, S., Gessler, C., and Patocchi, A.

Subjects
Apple -- Genetic aspects, Apple -- Research, Chromosome mapping -- Research, Plant immunology -- Research, Biological sciences
Abstract

Abstract: Apple scab, caused by the fungus Venturia inaequalis, is the major production constraint in temperate zones with humid springs. Normally, its control relies on frequent and regular fungicide applications. [...]

Published
2006

31. Contributors

Author

Adler, Sharon, primary, Adrogué, Horacio J., additional, Aiyagari, Venkatesh, additional, Alpern, Robert J., additional, Alpers, Charles E., additional, Appel, Gerald B., additional, Arogundade, Fatiu A., additional, Ash, Stephen R., additional, Asif, Arif, additional, Aucouturier, Pierre, additional, August, Phyllis, additional, Bakris, George L., additional, Barlow, Adam D., additional, Barsoum, Rashad S., additional, Baylis, Chris, additional, Bello, Aminu, additional, Berl, Tomas, additional, Bhat, Suresh, additional, Bircher, Gemma, additional, Bonventre, Joseph V., additional, Bouchard, Josée, additional, Brook, Nicholas R., additional, Brown, Christopher, additional, Brown, Mark A., additional, Burdmann, Emmanuel A., additional, Bushinsky, David A., additional, Cattran, Daniel C., additional, Cervelli, Matthew J., additional, Chadban, Steven J., additional, Charlton, Karen E., additional, Chen, Yipu, additional, Cheng, Ignatius K.P., additional, Connolly, John O., additional, Couser, William G., additional, Cravedi, Paolo, additional, D’Agati, Vivette D., additional, Danovitch, Gabriel M., additional, Davies, Simon J., additional, Davison, John M., additional, Derman, Wayne, additional, DiBona, Gerald F., additional, Drüeke, Tilman B., additional, Dwyer, Jamie P., additional, Eckardt, Kai-Uwe, additional, Eckel, Jason, additional, Eitner, Frank, additional, Kossi, Mohsen El, additional, Elger, Marlies, additional, Elhassan, Elwaleed A., additional, Evenepoel, Pieter, additional, Fabian, June, additional, Falk, Ronald J., additional, Feehally, John, additional, Fischer, Evelyne A., additional, Fisher, Jonathan S., additional, Floege, Jürgen, additional, Fogazzi, Giovanni B., additional, Foreman, John W., additional, Fujita, Toshiro, additional, Gennari, F. John, additional, Gkougkousis, Evangelos G., additional, Glassock, Richard J., additional, Gorelick, Philip B., additional, Greco, Barbara A., additional, Gross, Peter, additional, Guay-Woodford, Lisa M., additional, Haddad, Nabil, additional, Harris, Kevin P.G., additional, Harris, Peter C., additional, Hebert, Lee A., additional, Heduschka, Peter, additional, Herzog, Charles A., additional, Hooton, Thomas, additional, Hörl, Walter H., additional, Hoyer, Peter F., additional, Hughes, Jeremy, additional, Hugo, Christian, additional, Imai, Enyu, additional, Irish, Ashley B., additional, Jaber, Bertrand L., additional, Jain, Sunjay, additional, Jayne, David, additional, Jefferson, J. Ashley, additional, Jennette, J. Charles, additional, Jha, Vivekanand, additional, Johnson, Richard J., additional, Kanagasundaram, Nigel S., additional, Kanellis, John, additional, Karumanchi, S. Ananth, additional, Kashtan, Clifford E., additional, Kauffman, Carol A., additional, Kawar, Bisher, additional, Kestenbaum, Bryan, additional, Ketteler, Markus, additional, Kopp, Jeffrey, additional, Kotanko, Peter, additional, Kriz, Wilhelm, additional, Kuhlmann, Martin K., additional, Kuypers, Dirk R., additional, Lakey, Jonathan R.T., additional, Lambert, Estelle V., additional, Lawton, William, additional, Levey, Andrew S., additional, Levin, Nathan W., additional, Levy, Jeremy, additional, Lewington, Andrew, additional, Lewis, Julia B., additional, Li, Felix F.K., additional, Linas, Stuart L., additional, Luft, Friedrich C., additional, Maaten, Jan C. ter, additional, Macdougall, Iain C., additional, Macedo, Etienne, additional, Madias, Nicolaos E., additional, Magee, Colm C., additional, Marsh, Christopher L., additional, Marshall, Mark R., additional, Martin, Kevin J., additional, Mason, Philip D., additional, Mathews, Ranjiv, additional, Mattoo, Tej K., additional, Mehta, Ravindra L., additional, Meier-Kriesche, Herwig-Ulf, additional, Mellon, J. Kilian, additional, Mirbolooki, M. Reza, additional, Monk, Rebeca D., additional, Moulin, Bruno, additional, Mulley, William R., additional, Nahas, Meguid El, additional, Naicker, Saraladevi, additional, Nangaku, Masaomi, additional, Neild, Guy H., additional, Nicholls, M. Gary, additional, Nicholson, Michael L., additional, O’Connell, Philip J., additional, O’Neill, W. Charles, additional, Palmer, Biff F., additional, Parikh, Chirag, additional, Pham, Phuong-Chi T., additional, Pham, Phuong-Thu T., additional, Pham, Son V., additional, Phelps, Richard G., additional, Pichler, Raimund, additional, Podymow, Tiina, additional, Pommer, Wolfgang, additional, Pusey, Charles D., additional, Rabb, Hamid, additional, Rayner, Brian, additional, Rayner, Hugh C., additional, Remuzzi, Giuseppe, additional, Richards, A. Mark, additional, Rippe, Bengt, additional, Ritz, Eberhard, additional, Robertson, R. Paul, additional, Rodriguez-Iturbe, Bernardo, additional, Ronco, Claudio, additional, Ronco, Pierre M., additional, Ross, Edward A., additional, Rossert, Jerome A., additional, Ruggenenti, Piero, additional, Ruland, Sean, additional, Russ, Graeme R., additional, Samuels, Martin A., additional, Sarafidis, Pantelis A., additional, Schena, F. Paolo, additional, Schold, Jesse D., additional, Schrier, Robert W., additional, Seabra, Victor F., additional, Segal, Mark S., additional, Seifter, Julian Lawrence, additional, Shastri, Shani, additional, Shirley, David G., additional, Sitprija, Visith, additional, Srinivas, Titte R., additional, Stenvinkel, Peter, additional, Stevens, Lesley A., additional, Textor, Stephen C., additional, Thurman, Joshua M., additional, Tong, Li-Li, additional, Topham, Peter S., additional, Tordoir, Jan H.M., additional, Torres, Vicente E., additional, Trence, Dace, additional, Turner, A. Neil, additional, Unwin, Robert J., additional, Vacher-Coponat, Henri, additional, Visweswaran, R. Kasi, additional, Wasse, Haimanot, additional, Wavamunno, Moses D., additional, Weiner, I. David, additional, Wheeler, David C., additional, Williams, Bryan, additional, Williams, John D., additional, Wingo, Charles S., additional, Winn, Michelle, additional, Wiseman, Alexander C., additional, Wolf, Gunter, additional, Womer, Karl, additional, Woodrow, Graham, additional, Wymer, David C., additional, Yang, Li, additional, and Yu, Xueqing, additional

Published
2010
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35. Contributors

Author

Ambarsari, Cahyani Gita, Annunziato, Rachel A., Anvari, Evamaria, Araya, Carlos E., Attini, Rossella, Ayoob, Rose Mary, Bacchetta, Justine, Baracco, Rossana, Bargman, Joanne M., Bellasi, Antonio, Bellorin-Font, Ezequiel, Bennett, William M., Bieber, Scott, Bissonnette, Mei Lin Z., Block, Geoffrey A., Bowman, Brendan, Brophy, Patrick D., Brouwer-Maier, Deborah J., Brunelli, Steven, Bushinsky, David, Casavant, Jonathan, Cerutti, Roberta, Chadha, Vimal, Chan, Christopher T., Chand, Bipan, Chand, Deepa H., Chang, Anthony, Charytan, Chaim, Chen, Joline L.T., Chen, Wei, Chin, Andrew I., Cho, Yeoungjee, Clark, William R., Crabtree, John H., Cukor, Daniel, Deger, Serpil Muge, Del Vecchio, Lucia, Diaz, Alonso R., Donahue, Stephanie L., Dukkipati, Ramanath, Dunphy, Claire, Elbokl, Mohamed, Fabrizi, Fabrizio, Faizan, Mohammed K., Fishbane, Steven, Fisher, Molly, Fissell, William Henry, IV, Fonseca-Correa, Jorge Ignacio, Foster, Bethany J., Furgeson, Seth B., Gefen, Ashley M., Gembillo, Guido, Gennari, F. John, Ghannoum, Marc, Glorieux, Griet, Greenwood, Sharlene Anuska, Haffner, Dieter, Himmele, Rainer, Holley, Jean L., Hothi, Daljit K., Ikizler, T. Alp, Jassal, Sarbjit Vanita, Johansen, Kirsten L., Johnson, David W., Kalantar-Zadeh, Kamyar, Kathuria, Pranay, Khan, Irfan, Kimmel, Paul L., Kliger, Alan S., Koh Jee Kam, Timothy, Korucu, Berfu, Koufaki, Pelagia, Kovalik, Eugene C., Kremsdorf, Robin A., Kreuzer, Martin, Krishnan, Mahesh, Kuhlmann, Martin K., Lam, Danica, Lapid, Yu-Chi, Locatelli, Francesco, Lockridge, Joseph B., Lok, Charmaine E., Macedo, Etienne, Mahan, John D., Manley, Harold J., Martin, Kevin J., Matthews, Nicola, Mayes, Juliet, McCoy, Ian E., Mcintyre, Christopher W., Mehrotra, Rajnish, Mehta, Ravindra L., Mitsnefes, Mark M., Mokrzycki, Michele H., Momciu, Bogdan, Mooney, Liz, Moss, Alvin H., Narasimha Krishna, Vinay, Nessim, Sharon J., Nissenson, Allen R., Niyyar, Vandana Dua, Olyaei, Ali, Orozco-Guillén, Alejandra, Ortiz-Melo, David I., Palmer, Biff F., Palmer, Suetonia C., Parfrey, Patrick S., Perl, Jeffery, Piccoli, Giorgina B., Pittard, Joanne D., Rhee, Connie M., Ridruejo, Ezequiel, Rigatto, Claudio, Rivara, Matthew B., Roberts, Darren M., Rodriguez, AnnaMarie, Rodriguez, Mariano, Rodriguez, Rudolph A., Ronco, Claudio, Rosner, Mitchell H., Sadler, John H., Saglimbene, Valeria, Salerno, Fabio R., Santoro, Domenico, Schaefer, Franz, Sethna, Christine B., Shah, Hitesh H., Shen, Jenny I., Silberzweig, Jeffrey, Siligato, Rossella, Singer, Pamela S., Somers, Michael J.G., Soo, Spinowitz, Bruce, Stein, Deborah, Stonebrook, Emily, Strippoli, Giovanni F.M., Szeto, Cheuk-Chun, Teitelbaum, Isaac, Thomas-Chen, Rebecca, Tolwani, Ashita J., Torreggiani, Massimo, Traum, Avram Z., Tulloch-Palomino, Luis G., Vachharajani, Tushar J., Valentini, Rudolph P., Van Buren, Peter Noel, VanDeVoorde, René G., III, Vanholder, Raymond, Vo, Thanh-Mai, Warady, Bradley A., Weinstein, Adam, Wesseling-Perry, Katherine, Wetmore, James B., Williams, Mark E., Wish, Jay B., and Zaritsky, Joshua J.

Published
2023
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38. CONTRIBUTORS

Author

Acchiardo, Sergio R., primary, Agarwal, Rajiv, additional, Al-Uzri, Amira, additional, Anderson, Connie, additional, Armenti, Vincent T., additional, Ash, Stephen R., additional, Avram, Morrell Michael, additional, Bellasi, Antonio, additional, Benfield, Mark R., additional, Bennett, William M., additional, Berns, Jeffrey S., additional, Besarab, Anatole, additional, Blagg, Christopher R., additional, Block, Geoffrey A., additional, Boccardo, Paola, additional, Bolton, W. Kline, additional, Brandt, Mary L., additional, Brewer, Eileen D., additional, Brophy, Patrick D., additional, Brown, Warren S., additional, Bunnapradist, Suphamai, additional, Burkart, John M., additional, Campese, Vito M., additional, Caruana, Ralph J., additional, Cass, Darrell L., additional, Chadha, Vimal, additional, Chan, Christopher T., additional, Charytan, Chaim, additional, Clark, William R., additional, Collins, Allan J., additional, Cramer, Carl H., additional, Crawford-Bonadio, Terri L., additional, Freitas, Declan de, additional, Diaz-Buxo, José A., additional, Dinwiddie, Lesley C., additional, Ellis, Eileen N., additional, Englund, Janet A., additional, Fabrizi, Fabrizio, additional, Feinfeld, Donald A., additional, Foulks, Charles Jerome, additional, Fouque, Denis, additional, Galbusera, Miriam, additional, Gao, Dayong, additional, Gennari, F. John, additional, Giullian, Jeffrey, additional, Goldstein, Stuart L., additional, Gonzalez, Esther A., additional, Goodman, William G., additional, Gotch, Frank A., additional, Haghighat, Leila, additional, Harbord, Nikolas B., additional, Harvey, Elizabeth, additional, Hoenich, Nicholas Andrew, additional, Holmberg, Christer, additional, Holmes, Clifford J., additional, Hootkins, Robert, additional, Hothi, Daljit K., additional, Hou, Susan, additional, Hutchison, Alastair J., additional, Huang, Zhongping, additional, Ing, Todd S., additional, Johnson, Curtis A., additional, Kalantar-Zadeh, Kamyar, additional, Kaplan, André A., additional, Kapoian, Toros, additional, Kaptein, Elaine M., additional, Kathuria, Pranay, additional, Kaufman, Jeffrey L., additional, Keane, William F., additional, Khanna, Ramesh, additional, Khosla, Neenoo, additional, Kimmel, Paul L., additional, Kjellstrand, Carl M., additional, Kooienga, Laura, additional, Kotanko, Peter, additional, Kovalik, Eugene C., additional, Kraemer, Matthias, additional, Langone, Anthony, additional, Lawrence, Peter F., additional, Letteri, Jeffrey J., additional, Leung, Chi-Bon, additional, Levin, Adeera, additional, Levin, Nathan W., additional, Leypoldt, John Kenneth, additional, Li, Philip Kam-Tao, additional, Lindsay, Robert McGregor, additional, Llach, Francisco, additional, MacDougall, Margaret, additional, Mailloux, Lionel U., additional, Martin, Kevin J., additional, Martin, Paul, additional, Massy, Ziad A., additional, McFarlane, Philip A., additional, Mehrotra, Rajnish, additional, Mitsnefes, Mark M., additional, Mittman, Neal, additional, Moritz, Michael J., additional, Mulloy, Laura L., additional, Murphy, Sean W., additional, Negoi, Dana, additional, Neu, Alicia M., additional, Nikakhtar, Bijan, additional, Nissenson, Allen R., additional, Nouri, Pouneh, additional, Nuchtern, Jed G., additional, Oliver, Matthew J., additional, Olyaei, Ali J., additional, Pahl, Madeleine V., additional, Painter, Patricia, additional, Palmer, Biff F., additional, Parfrey, Patrick S., additional, Perilloux, Ashley A., additional, Pham, Phuong-Chi T., additional, Pham, Phuong-Thu T., additional, Pierratos, Andreas, additional, Pittard, Joanne D., additional, Pun, Patrick H., additional, Qvist, Erik, additional, Raj, Dominic S.C., additional, Remuzzi, Giuseppe, additional, Rigatto, Claudio, additional, Rocco, Michael V., additional, Rodriguez, Rudolph A., additional, Ronco, Claudio, additional, Rönnholm, Kai, additional, Rosner, Mitchell H., additional, Sadler, John H., additional, Salusky, Isidro B., additional, Sam, Ramin, additional, Sanchez, Cheryl P., additional, Satko, Scott G., additional, Schaefer, Franz, additional, Schmidt, Rebecca J., additional, Schröder, Cornelis H., additional, Schulman, Gerald, additional, Schwab, Steve J., additional, Schwenk, Michael H., additional, Shapiro, Warren B., additional, Sherman, Richard A., additional, Smith, Jodi M., additional, Somers, Michael J.G., additional, Spanner, Evelyn, additional, Spinowitz, Bruce S., additional, Stivelman, John C., additional, Szeto, Cheuk-Chun, additional, Tannenberg, Alf M., additional, Tipton, Karen B., additional, Traum, Avram Z., additional, Tsai, Arthur, additional, Twardowski, Zbylut J., additional, Tzamaloukas, Antonios H., additional, Vanholder, Raymond, additional, Vaziri, Nosratola D., additional, Wakeen, Maureen, additional, Warady, Bradley A., additional, Ward, Richard A., additional, Wassner, Steven J., additional, Weisbord, Steven D., additional, White, John J., additional, White, Suzanne H., additional, Winchester, James F., additional, Windus, David W., additional, Wish, Jay B., additional, Zappacosta, Anthony R., additional, and Zimmerman, Stephen W., additional

Published
2008
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50. Hypokalemia

Author

Gennari, F. John

Subjects
Hypokalemia -- Analysis
Abstract

Hypokalemia is best prevented by eating a diet with adequate potassium levels. Hypokalemia is the medical term for low blood potassium levels. This condition is only dangerous if the levels are extremely low or the person has a history of heart disease. Symptoms are only present during severe hypokalemia and include weakness, constipation, paralysis and breathing difficulties. Patient with heart disease are at risk of arrhythmias if their blood potassium drops too low. Certain drugs are the most common cause of hypokalemia, as well as excessive diarrhea. Potassium supplements are the most effective treatment.

Published
1998

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