Search

Your search keyword '"Genc, Halil"' showing total 35 results
Start Over Author "Genc, Halil"
35 results on '"Genc, Halil"'

1. Predictive of Perceived Learning: Academic Motivation and Attitudes to Mobile Learning

Author

Turan, Serhat, Yaman, M. Sibel, Genc, Halil Ibrahim, Donmez, Ahmet, Herguner, Gülten, and Yaman, Çetin

Abstract

In this research, it was aimed to determine the predictive power of academic motivation and attitudes towards mobile learning on perceived learning in sports science students. 416 (197 female+219 male) sports science students were included in the research, which was conducted in accordance with the correlational survey model. In the research, "Perceived Learning Scale", Academic Motivation Scale" "Mobile Learning Attitude Scale" and "Personal Information Form" were used as data collection tools. Data were analyzed with descriptive statistics, Pearson correlation and Regression analysis. When the findings of the study were examined, positive moderate and significant relationships were found between perceived learning and academic motivation in sports science students (p<0.05), and positive low-level significant relationships were found with mobile learning (p<0.05). In addition, it was determined that academic motivation and attitude towards mobile learning positively predicted learning (p<0.05). As a result, if perceived learning is desired to increase in a positive way, this research has shown that academic motivation and mobile learning are important variables that can affect this.

Published
2022

15. Insulin Resistance but Not Visceral Adiposity Index Is Associated with Liver Fibrosis in Nondiabetic Subjects with Nonalcoholic Fatty Liver Disease

Author

Ercin, Cemal Nuri, primary, Dogru, Teoman, additional, Genc, Halil, additional, Celebi, Gurkan, additional, Aslan, Fatih, additional, Gurel, Hasan, additional, Kara, Muammer, additional, Sertoglu, Erdim, additional, Tapan, Serkan, additional, Bagci, Sait, additional, Rizzo, Manfredi, additional, and Sonmez, Alper, additional

Published
2015
Full Text
View/download PDF

16. The relationship of circulating fetuin-a with liver histology and biomarkers of systemic inflammation in nondiabetic subjects with nonalcoholic fatty liver disease

Author

Celebi, Gurkan, primary, Genc, Halil, additional, Gurel, Hasan, additional, Kara, Muammer, additional, Acikel, Cengizhan, additional, Ercin, CemalNuri, additional, Dogru, Teoman, additional, Sertoglu, Erdim, additional, Tapan, Serkan, additional, and Karslioglu, Yildirim, additional

Published
2015
Full Text
View/download PDF

17. Transforming growth factor beta (TGF-beta) levels in otherwise healthy subjects with impaired glucose tolerance

Author

Genc, Halil, Karadurmus, Nuri, Kisa, Ucler, Tapan, Serkan, Naharci, Ilkin, Sonmez, Alper, Dogru, Teoman, and Kırıkkale Üniversitesi

Subjects
impaired glucose tolerance, cytokine, TGF-beta
Abstract

KISA, Ucler/0000-0002-8131-6810; Naharci, Mehmet/0000-0003-2730-7144; GENC, HALIL/0000-0002-0229-1695; Sonmez, Alper/0000-0002-9309-7715 WOS: 000208625900008 PubMed: 21104643 Introduction: Serum transforming growth factor beta (TGF-beta) level is increased in type-2 diabetes mellitus (T2DM) and certain diabetic complications are mediated by this cytokine. Impaired glucose tolerance (IGT) is a prediabetic condition, and confers a risk for the development of certain diabetes-specific complications. However, no data is available regarding the alteration of TGF-beta in IGT subjects. Therefore, we aimed to investigate TGF-beta levels in otherwise healthy subjects with IGT. Material and methods: Thirty IGT subjects and 30 subjects relatively matched for age, sex and body mass index with normal glucose tolerance were enrolled. Subjects with overt diabetes, cardiovascular, renal or inflammatory disease, or on any medication were excluded. Relevant laboratory examinations were performed by routine methods. Assessment of TGF-beta was made by a commercially available enzyme-linked immunosorbent assay kit. IGT and control subjects were compared for their clinical and laboratory parameters. Results: Serum TGF-beta levels were found to be similar in IGT and normal glucose tolerance subjects (p < 0.05). No statistically significant correlation was found between TGF-beta and other laboratory parameters, either in IGT subjects or in the whole study population. Conclusions: Serum TGF-beta is not elevated in otherwise healthy subjects with IGT. The results of our study imply that the presence of IGT alone is not sufficient to induce TGF-beta elevation; and for the alteration of TGF-beta, worsening of metabolic risk factors may be required. (Pol J Endocrinol 2010; 61 (6): 691-694) Gulhane MilitaryMedical Academy This study is financially supported by grants from Gulhane MilitaryMedical Academy. There is no conflict of interest.

Published
2010

18. Relationship between hemoglobin and CD40 ligand in prediabetes

Author

Kutlu, Mustafa, Sonmez, Alper, Genc, Halil, Erdem, Gokhan, Tapan, Serkan, Celebi, Gurkan, Haymana, Cem, Taslipinar, Abdullah, Uckaya, Gokhan, Erbil, Mehmet Kemal, Kutlu, Mustafa, Sonmez, Alper, Genc, Halil, Erdem, Gokhan, Tapan, Serkan, Celebi, Gurkan, Haymana, Cem, Taslipinar, Abdullah, Uckaya, Gokhan, and Erbil, Mehmet Kemal

Abstract

Purpose: Hemoglobin (Hb) regulates the endothelial function by modulating the bio-availability of NO at the tissue level. A significant direct relationship is present between the Hb levels and endothelial functions in patients with Type 2 diabetes. Testing whether this association also exists in subjects with prediabetes is important because prediabetes is associated with an increased risk of cardiovascular disease and mortality. Therefore, we investigated the association of Hb both with the classical cardiac risk factors and the markers for endothelial dysfunction and inflammation, in subjects with impaired glucose tolerance (IGT). Methods: We enrolled 69 normotensive, and cardiovascular events free subjects with IGT (M=40, age=45.50±6.8 yr). Plasma insulin, hsCRP, soluble CD40L, vonWillebrand factor, p-selectin levels were measured. The parameters given according to the higher and lower median Hb values of the subjects were compared. Results: Subjects with the higher Hb levels exhibited lower HDL-C (46.68±10.8 mg/dl vs 51.5±8.9mg/dl; P=0.04) and higher systolic (122.57±6.2mmHg vs 116.17±7.4mmHg; p < 0.001) and diastolic (79.14±3.73mmHg vs 75.58±6.1mmHg; P=0.005) blood pressures and sCD40L (7.9±3.8ng/ml vs 6.07±2.1 ng/ml; P=0.02) levels. Hb levels were correlated to the HDL cholesterol, sCD40L, systolic and diastolic blood pressures and waist circumference (r=-0.28, P=0.02; r=0.29, P=0.02; r=0.53, P < 0.001; r=0.41, P=0.001; r=0.42, P < 0.001 respectively). According to the multiple logistic regression analysis, Hb was the determinant of sCD40L levels (?=0.437, P < 0.001). Conclusion: These results indicate that there may be a link with higher Hb values and cardiovascular risk factors in patients with IGT. Further investigation is warranted to understand the clinical implications of these findings in subjects with prediabetes.

Published
2009

25. Circulating vaspin and its relationship with insulin sensitivity, adiponectin, and liver histology in subjects with non-alcoholic steatohepatitis

Author

Genc, Halil, primary, Dogru, Teoman, additional, Tapan, Serkan, additional, Kara, Muammer, additional, Ercin, Cemal Nuri, additional, Aslan, Fatih, additional, Kantarcioglu, Murat, additional, Karslioglu, Yildirim, additional, Sertoglu, Erdim, additional, Erbil, Mehmet Kemal, additional, and Bagci, Sait, additional

Published
2011
Full Text
View/download PDF

27. Mean platelet volume and its relationship with carotid atherosclerosis in subjects with non-alcoholic fatty liver disease

Author

Kilciler, Guldem, primary, Genc, Halil, additional, Tapan, Serkan, additional, Ors, Fatih, additional, Kara, Muammer, additional, Karadurmus, Nuri, additional, Ercin, C. Nuri, additional, Karslioglu, Yildirim, additional, Kilic, Selim, additional, Bagci, Sait, additional, Erbil, M. Kemal, additional, and Dogru, Teoman, additional

Published
2010
Full Text
View/download PDF

29. Plasma Apelin and ADMA Levels in Patients with Essential Hypertension

Author

Sonmez, Alper, primary, Celebi, Gurkan, additional, Erdem, Gokhan, additional, Tapan, Serkan, additional, Genc, Halil, additional, Tasci, Ilker, additional, Ercin, Cemal Nuri, additional, Dogru, Teoman, additional, Kilic, Selim, additional, Uckaya, Gokhan, additional, Yilmaz, Mahmut Ilker, additional, Erbil, Mehmet Kemal, additional, and Kutlu, Mustafa, additional

Published
2010
Full Text
View/download PDF

31. Relationship between hemoglobin and CD40 ligand in prediabetes

Author

Kutlu, Mustafa, primary, Sonmez, Alper, additional, Genc, Halil, additional, Erdem, Gokhan, additional, Tapan, Serkan, additional, Celebi, Gurkan, additional, Haymana, Cem, additional, Taslipinar, Abdullah, additional, Uckaya, Gokhan, additional, and Erbil, Mehmet Kemal, additional

Published
2009
Full Text
View/download PDF

34. The presence of MEFV gene mutations in patients with primary osteoarthritis who require surgery.

Author

Yilmaz S, Erdem H, Tunay S, Torun D, Genc H, Tunca Y, Karadag O, Simsek I, Bahce M, Pay S, and Dinc A

Subjects
Adolescent, Adult, Case-Control Studies, Chi-Square Distribution, DNA Mutational Analysis, Familial Mediterranean Fever diagnosis, Familial Mediterranean Fever epidemiology, Female, Gene Frequency, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Osteoarthritis, Hip diagnosis, Osteoarthritis, Hip epidemiology, Osteoarthritis, Hip surgery, Osteoarthritis, Knee diagnosis, Osteoarthritis, Knee epidemiology, Osteoarthritis, Knee surgery, Phenotype, Pyrin, Risk Factors, Turkey epidemiology, Young Adult, Cytoskeletal Proteins, Familial Mediterranean Fever genetics, Mutation, Osteoarthritis, Hip genetics, Osteoarthritis, Knee genetics
Abstract

Background/aims: Chronic arthritis of familial Mediterranean fever (FMF) involves weight-bearing joints and can occur in patients without a history of acute attack. Our aim was to investigate a possible causal relationship between FMF and osteoarthritis in a population in which FMF is quite common., Methods: Patients with late stage primary osteoarthritis were enrolled, and five MEFV gene mutations were investigated. The frequency of MEFV gene mutations was compared among patients with osteoarthritis and a previous healthy group from our center., Results: One hundred patients with primary osteoarthritis and 100 healthy controls were studied. The frequency of MEFV gene mutations was significantly lower in the osteoarthritis group (9% vs. 19%). M694V was the most frequent mutation (5%) in the osteoarthritis group, whereas in the control group, E148Q was the most common (16%). In subgroup analyses, the mutation frequency of patients with hip osteoarthritis was not different from that of patients with knee osteoarthritis and controls (7.1%, 9.7%, and 19%, respectively). There were no differences among the three groups with respect to MEFV gene mutations other than E148Q (8.1% vs. 3.6%). E148Q was significantly lower in the osteoarthritis group than in the controls (16% vs. 1%), although the mutations did not differ between patients with knee osteoarthritis and controls., Conclusions: In a population with a high prevalence of MEFV gene mutations, we did not find an increased mutation rate in patients with primary osteoarthritis. Furthermore, we found that some mutations were significantly less frequent in patients with osteoarthritis. Although the number of patients studied was insufficient to claim that E148Q gene mutation protects against osteoarthritis, the potential of this gene merits further investigation.

Published
2013
Full Text
View/download PDF

35. Transforming growth factor β (TGF-β) levels in otherwise healthy subjects with impaired glucose tolerance.

Author

Genc H, Karadurmus N, Kisa U, Tapan S, Naharci I, Sonmez A, and Dogru T

Subjects
Adult, Female, Humans, Male, Glucose Intolerance blood, Prediabetic State blood, Transforming Growth Factor beta blood
Abstract

Introduction: Serum transforming growth factor beta (TGF-β) level is increased in type-2 diabetes mellitus (T2DM) and certain diabetic complications are mediated by this cytokine. Impaired glucose tolerance (IGT) is a prediabetic condition, and confers a risk for the development of certain diabetes-specific complications. However, no data is available regarding the alteration of TGF-β in IGT subjects. Therefore, we aimed to investigate TGF-β levels in otherwise healthy subjects with IGT., Material and Methods: Thirty IGT subjects and 30 subjects relatively matched for age, sex and body mass index with normal glucose tolerance were enrolled. Subjects with overt diabetes, cardiovascular, renal or inflammatory disease, or on any medication were excluded. Relevant laboratory examinations were performed by routine methods. Assessment of TGF-β was made by a commercially available enzyme-linked immunosorbent assay kit. IGT and control subjects were compared for their clinical and laboratory parameters., Results: Serum TGF-β levels were found to be similar in IGT and normal glucose tolerance subjects (p 〈 0.05). No statistically significant correlation was found between TGF-β and other laboratory parameters, either in IGT subjects or in the whole study population., Conclusions: Serum TGF-β is not elevated in otherwise healthy subjects with IGT. The results of our study imply that the presence of IGT alone is not sufficient to induce TGF-β elevation; and for the alteration of TGF-β, worsening of metabolic risk factors may be required.

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results