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Objective: Spinal meningiomas are rare diseases of the vertebral column. While cerebral meningiomas have been thoroughly studied, further investigations on spinal meningiomas are urgently needed. This study aimed to evaluate the treatment & outcome of surgically treated patients with spinal meningiomas [for full text, please go to the a.m. URL]

Objective: The transnasal binostril endoscopic resection of pituitary adenomas is regarded as a minimally invasive treatment nowadays. However, sino-nasal outcome and quality of life (QoL) might still be impaired after the resection of pituitary adenomas, depending on patients' prior medical history [for full text, please go to the a.m. URL]

Objective: Brain natriuretic peptide (BNP) serum levels on admission have been implemented in the prediction of functional outcomes of several cerebrovascular diseases. The potential role of BNP in the prediction of outcomes after aneurysmatic subarachnoid hemorrhage (aSAH) has not yet been addressed. [for full text, please go to the a.m. URL]

Objective: Chronic subdural hematoma (cSDH) is a multifactorial disease with a not well understood pathophysiology. High rates of recurrence and postoperative morbidity still represent a financial threat on health systems. Cost-utility analyses (CUA) evaluating health improvement after empiric surgical [for full text, please go to the a.m. URL]

Objective: Cubital Tunnel Syndrome (CuTS) is a common nerve damage that leads to motor and sensory deficits in the hand. Many patients present with pronounced muscle atrophy and hand dysfunction as a sign of severe nerve impairment. This prospective study aims to clarify if those patients benefit from [for full text, please go to the a.m. URL]

Objective: Chordoma is a rare disease that belongs to the group of malignant bone and soft tissue tumors of sarcomas. It is a locally aggressive, osteodestructive, metastasizing tumor with preferred localization in the skull base and sacrum. Due to the anatomic localization and infiltration, complete [for full text, please go to the a.m. URL]

Objective: The preferred neurosurgical route to resect lesions of the skull base, such as pituitary adenomas, is the transnasal endoscopic approach. Though commonly accepted as a gentle treatment, it has been reported that nasal health may be diminished after surgery. A systematic pre-/postoperative[for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: Peripheral nerve tumors are rare and sometimes difficult to diagnose. Despite recent advances in diagnostic tools and the more commonly use of ultrasound, MRI and electrophysiology, time until diagnosis of peripheral nerve tumors is quite long and they can be mistreated prior to diagnosis.[for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: A recent study showed a frequent elevation of brain natriuretic peptide (BNP) serum levels in patients with symptomatic chronic subdural hematoma (cSDH). In this study, the prediction of the long-term functional outcome was assessed, and a new predictive score developed. Methods: We[for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: Thrombosed intracranial aneurysms (ICA) are often associated with increased aneurysm wall instability. Recently, contrast enhancement in the aneurysm wall of thrombosed ICAs could be visualized in vivo using high-resolution gadolinium-enhanced 7 Tesla (T) magnetic resonance imaging (MRI).[for full text, please go to the a.m. URL], 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Objective: To report on clinical application as well as the advantages and disadvantages of ultra-high-field 7T MRI in a neurosurgical setting. Methods: Since 2008 eligible neurosurgical patients were prospectively examined on a 7T whole-body MR system (Magnetom 7T, Siemens Healthcare Sector) equipped[for full text, please go to the a.m. URL], 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Objective: External ventricular drainage (EVD) is frequently used in pediatric brain surgery. During the externalization of cerebrospinal fluid (CSF), catheter-associated meningitis (CAM) remains a major issue. This study aimed to evaluate the incidence of CAM in a pediatric population and to elucidate[for full text, please go to the a.m. URL], 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Objective: Several parameters are known to predict the survival of glioblastoma (GBM) comprising extend of resection and MGMT promotor methylation. Staining for glial fibrillary acidic protein (GFAP) is being frequently assessed during histological work-ups, however its clinical utility for GBM remains[for full text, please go to the a.m. URL], 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Objective: Tuberous sclerosis complex (TSC) is a rare multisystem genetic disease. Arterial wall developmental disorders in TSC such as aneurysms have been well described for extracranial vasculature. The characteristics of intracranial aneurysms (IA) in TSC have not been addressed in the literature[for full text, please go to the a.m. URL], 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Objective: Cervical spondylotic myelopathy (CSM), a slowly ongoing disease, is the most common reason for spinal cord injuries. Up to now, timing of surgical treatment still varies. In this study we analyzed the postoperative outcome of patients suffering from CSM with and without signs of myelopathy[for full text, please go to the a.m. URL], 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Knowledge of the exact tumor location and structures at risk in its vicinity are crucial for neurosurgical interventions. Neuronavigation systems support navigation within the patient's brain, based on preoperative MRI (preMRI). However, increasing tissue deformation during the course of tumor resection reduces navigation accuracy based on preMRI. Intraoperative ultrasound (iUS) is therefore used as real-time intraoperative imaging. Registration of preMRI and iUS remains a challenge due to different or varying contrasts in iUS and preMRI. Here, we present an automatic and efficient segmentation of B-mode US images to support the registration process. The falx cerebri and the tentorium cerebelli were identified as examples for central cerebral structures and their segmentations can serve as guiding frame for multi-modal image registration. Segmentations of the falx and tentorium were performed with an average Dice coefficient of 0.74 and an average Hausdorff distance of 12.2 mm. The subsequent registration incorporates these segmentations and increases accuracy, robustness and speed of the overall registration process compared to purely intensity-based registration. For validation an expert manually located corresponding landmarks. Our approach reduces the initial mean Target Registration Error from 16.9 mm to 3.8 mm using our intensity-based registration and to 2.2 mm with our combined segmentation and registration approach. The intensity-based registration reduced the maximum initial TRE from 19.4 mm to 5.6 mm, with the approach incorporating segmentations this is reduced to 3.0 mm. Mean volumetric intensity-based registration of preMRI and iUS took 40.5 s, including segmentations 12.0 s. Keywords: IGNS, Image-guided neurosurgery, Intra-operative ultrasound, MRI, Registration, Segmentation

Objective: Perineuriomas (PN) are rare benign peripheral nerve sheath tumours with perineurial cell origin. Therapy regime is controversial and only sparse reports of single cases or small case series have been published. Aim of this report is to present our minimal surgical treatment regime and long-term[for full text, please go to the a.m. URL], 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS)

Objective: Deep-seated retroperitoneal neurinomas are very rare lesions causing a variety of symptoms. Because of their slow growth and deep-seated location with soft surrounding structures some can gain large size before initial diagnosis. This report presents an interdisciplinary treatment regime [for full text, please go to the a.m. URL], 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS)

Objective: We present a treatment approach for a rare condition of patients with a ventral C1 fracture and a congenital cleft in the posterior arch (half-ring Jefferson fracture) with an intact transverse atlantal ligament. Our technique aims to achieve stability of the atlanto-occipital and atlanto-axial[for full text, please go to the a.m. URL], 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS)

Objective: To measure anatomical variations in critical passages of C2 for the placement of anterior transarticular screws through C1/C2 compared to odontoid and posterior screw placement. Methods: 50 CT data volume scans of the cervical spine were anonymously analyzed with a total of 750 measurements[for full text, please go to the a.m. URL], 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS)

Objective: Pituitary surgery has incredibly evolved since the days of Oskar Hirsch and Harvey Cushing. Still, with technology evolving and limits of surgery being under constant changes there is need for improved simple and „on demand“ acquisition of high resolution imaging of the lesions[for full text, please go to the a.m. URL], 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)