1. Hybrid M-mode-like OCT imaging of 3D microvasculature in vivo using reference-free processing of complex-valued B-scans
- Author
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Matveev, Lev A., Zaitsev, Vladimir Yu., Gelikonov, Grigory V., Matveyev, Alexandr L., Moiseev, Alexander A., Ksenofontov, Sergey, Gelikonov, Valentin M., Demidov, Valentin, and Vitkin, Alex
- Subjects
Physics - Medical Physics ,Physics - Biological Physics ,Physics - Optics - Abstract
We propose a novel OCT-based method for visualizing microvasculature in 3D using reference-free processing of individual complex-valued B-scans with highly overlapped A-scans. In the lateral direction of such a B-scan, the amplitude and phase of speckles corresponding to vessel regions exhibit faster variability, and thus can be detected without comparison with other B-scans recorded in the same plane. This method combines elements of several existing OCT angiographic approaches, and exhibits: (i) enhanced robustness with respect to bulk tissue motion with frequencies up to tens of Hz; (ii) resolution of microcirculation images equal to that of structural images and (iii) possibility of quantifying the vessels in terms of their decorrelation rates., Comment: 4 pages, 2 figures
- Published
- 2014
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