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1. Quality indicators in intensive care medicine: why? Use or burden for the intensivist

Author

Waydhas, Christian, Steinmeier-Bauer, Klaus, Martin, Jörg, Quintel, Michael, Kuhlen, Ralf, Markewitz, Andreas, Kastrup, Marc, Geldner, Götz, Bloos, Frank, Spies, Claudia, Bause, Hanswerner, Mende, Hendrik, Braun, Jan-Peter, and NeQuI (quality network in intensive care medicine)

Subjects
quality indicators, quality management, intensive care medicine, quality of therapy, outcome, Medicine
Abstract

In order to improve quality (of therapy), one has to know, evaluate and make transparent, one’s own daily processes. This process of reflection can be supported by the presentation of key data or indicators, in which the real as-is state can be represented. Quality indicators are required in order to depict the as-is state. Quality indicators reflect adherence to specific quality measures. Continuing registration of an indicator is useless once it becomes irrelevant or adherence is 100%.In the field of intensive care medicine, studies of quality indicators have been performed in some countries. Quality indicators relevant for medical quality and outcome in critically ill patients have been identified by following standardized approaches. Different German societies of intensive care medicine have finally agreed on 10 core quality indicators that will be valid for two years and are currently recommended in German intensive care units (ICUs).

Published
2010

2. Peer reviewing critical care: a pragmatic approach to quality management

Author

Spies, Claudia, Waydhas, Christian, Steinmeier-Bauer, Klaus, Quintel, Michael, Martin, Jörg, Mende, Hendrik, Kuhlen, Ralf, Markewitz, Andreas, Kastrup, Marc, Bloos, Frank, Geldner, Götz, NeQuI (quality network in intensive care medicine), Bause, Hanswerner, and Braun, Jan-Peter

Subjects
peer review, quality management, intensive care medicine, evidence based medicine, effectiveness, Medicine
Abstract

Critical care medicine frequently involves decisions and measures that may result in significant consequences for patients. In particular, mistakes may directly or indirectly derive from daily routine processes. In addition, consequences may result from the broader pharmaceutical and technological treatment options, which frequently involve multidimensional aspects. The increasing complexity of pharmaceutical and technological properties must be monitored and taken into account. Besides the presence of various disciplines involved, the provision of 24-hour care requires multiple handovers of significant information each day. Immediate expert action that is well coordinated is just as important as a professional handling of medicine's limitations. Intensivists are increasingly facing professional quality management within the ICU (Intensive Care Unit). This article depicts a practical and effective approach to this complex topic and describes external evaluation of critical care according to peer reviewing processes, which have been successfully implemented in Germany and are likely to gain in significance.

Published
2010

4. Präoperative Evaluation erwachsener Patientinnen und Patienten vor elektiven, nicht herz-thoraxchirurgischen Eingriffen: Eine gemeinsame Empfehlung der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin, der Deutschen Gesellschaft für Chirurgie und der Deutschen Gesellschaft für Innere Medizin

Author

Zöllner, Christian, Böhmer, Andreas, Geldner, Götz, Karst, Jörg, Wappler, Frank, Zwissler, Bernhard, Pauschinger, Matthias, Obertacke, Udo, and Vilz, Tim

Subjects
RISK assessment, MEDICAL protocols, PATIENT education, COST control, PATIENT safety, UNNECESSARY surgery, NEGOTIATION, PREOPERATIVE care, CARDIOVASCULAR diseases risk factors, MEDICAL societies, INTERNATIONAL agencies, DECISION making, ROUTINE diagnostic tests, DRUGS, HEALTH facilities, HEALTH care teams, PERIOPERATIVE care
Abstract

Copyright of Die Anaesthesiologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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5. Adressen

Author

Geldner, Götz, primary, Alscher, Mark Dominik, additional, Baumbach, Hardy, additional, Berroth, Ralph, additional, Brinkmann, Alexander, additional, Bürle, Monica, additional, Caca, Karel, additional, Franke, Ulrich F. W., additional, Frey, Otto Roman, additional, Geldner, Götz, additional, Göbel, Nora, additional, König, Christina, additional, Kruth, Jens, additional, Kuntzen, Thomas, additional, Lichy, Gregor, additional, Lichy, Katrin, additional, Richter, Daniel, additional, Röhr, Anka C., additional, Schaible, Thomas, additional, Träger, Karl, additional, Wachter, Kristina, additional, and Wolpert, Christian, additional

Published
2019
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6. A randomized open label, parallel-group study to evaluate the hemodynamic effects of Cafedrine/Theodrenaline vs Noradrenaline in the treatment of intraoperative hypotension after induction of general anesthesia: the 'HERO' study design and rationale

Author

Vojnar, Benjamin, Geldner, Götz, Huljic-Lankinen, Susanne, Murst, Melanie, Keller, Thomas, Weber, Stephan, Gaik, Christine, Koch, Tilo, Weyland, Andreas, Kranke, Peter, Kreuer, Sascha, Chappell, Daniel, and Eberhart, Leopold

Subjects
General Medicine
Abstract

Intraoperative arterial hypotension (IOH) is associated with poor patient outcome. This study aims to compare the hemodynamic effects of Cafedrine/Theodrenaline (C/T) and Noradrenaline (NA) for the treatment of hypotension in patients who develop IOH after anesthesia induction. This is a national, randomized, parallel-group, multicenter, and open-label study. Adult patients (≥50 years, ASA-classification III–IV) who undergo elective surgery will be included. When IOH (MAP

Published
2023

8. Vorwort

Author

Geldner, Götz, primary and Alscher, Mark Dominik, additional

Published
2019
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9. Correction to: Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study

Author

Marx, Gernot, Litmathe, Jens, Schulz, Jörg B., Dafotakis, Manuel, Möllhoff, Thomas, Stalljohann, Carolin, Engels, Jonas, Sauerzapfe, Barbara, Stolzenberg, Barbara, Jonas, Engels, Möllhoff, Thomas, Carolin, Stalljohann, Thorben, Beeker, Gernot, Marx, Melanie, Schäfer, Tobias, Schürholz, Ertunc, Altiok, Marx, Nikolaus, Alexander, Kersten, Hannah, Dückers, Alexander, Koch, Trautwein, Christian, Scharf, Alexander, Kreuzer, Ilse, Jaschinski, Ulrich, Kreuzer, Ilse, Jaschinski, Ulrich, Niklas, Markus, Kulzer, Michael, Schlott, Martin, Iberer, Thomas, Stella, Oelert, Thorsten, Löhr, Vandana, Pillai, Praeger, Damaris, Knebel, Fabian, Baumann, Gert, Rosseau, Simone, Schlenk, Florian, Hoffmeister, Bodo, Compton, Friederike, Hoffmann, Clemens, Rademacher, Sibylle, Vietzke, Michael, Jörres, Achim, Meisel, Andreas, Hotter, Benjamin, Mengel, Annerose, Goldmann, Anton, Nöther, Frank, Keh, Didier, Schmidt, Katrin, Angermair, Stefan, Kaffarnik, Magnus, Bubser, Florian, Gummelt, Immo, Vedder, Ina, Bach, Friedhelm, Winter, Markus, Weißer, Frank, Roederer, Marc, Martini, Stefan, Bergmann, Lars, Adamzik, Michael, Baumann, Andreas, Wolf, Britta, Zahn, Peter K., Lehnhardt, Marcus, Daigeler, Adrien, Andreas, Andreas Hohn, Reinhold, Katrin, Adolf, Michael, Altenbeck, Nicole, Gussone, Christoph, Dietrich, Johannes Wolfgang, Köditz, Roland, Putensen, Christian, Schewe, Jens-Christian, Muders, Thomas, Soukup, Jens, Skitek, Kornel, Geisser, Wolfgang, Alber, Andreas, Düthorn, Ludwig, Demund, Josef, Düthorn, Ludwig, Criegern, Isabel v., Nowak, Andreas, Morgenstern, Toralf, Gliniorz, Christoph, Meisner, Michael, Dexel, Melanie, Schütte, Jan Karl, Huppertz-Thyssen, Markus H., Schröder, Stefan, Kowalzik, Ralf, Guel, Cansu, Terhorst, Rainer, Nießen, Peter, Hauschild, Rolf, Mutzek, Elisabeth-Maria, Kogelmann, Klaus, Drüner, Matthias, Jarczak, Dominik, Forster, Christian, Willam, Carsten, Eckardt, K. U., Clemenz, Rüdiger, Siemonsen, Sven, Pauschinger, Matthias, Baumgärtel, Matthias, Muschner, Dorothea, Christ, Michael, Wenzl, Martin, Höhl, Rainer, Junger, Axel, Wöhrle, Armin, Kanthak, Henry, Leschke, Matthias, Kanthak, Henry, Wöhrle, Armin, Leschke, Matthias, Kessler, Paul, Souquet, Jochen, Holfeld, Andreas, Habler, Oliver, Thörner, Markus, Vogt, Oliver, Meybohm, Patrick, Zacharowski, Kai, Lindau, Simone, Lenk, Marcus, Weis, Florian, Schubert, Hermann, Kemnitz, Jürgen, Reckort, Sven, Weikert, Martina, Sudhues, Ulrich, Möller, Stefan, Stefan, Pinger, Domke, Andrea, Wiesenack, Christoph, Schmidt, Florian, Döbel, Kai-Uwe, Moerer, Onnen, Schäper, Jörn, Kernchen, Andrea, Gründling, Matthias, Bollmann, Jan, Kuhn, Sven-Olaf, Kemming, Gregor, Einfeld, Carsten, Sommerer, Thomas, Kemming, Gregor, Einfeld, Carsten, Sommerer, Thomas, Köntges, Philipp, Hinz, Burkhard, Jauch, Lars-Oliver, Selonke, Lutz, Kluge, Stefan, Nierhaus, Axel, de Heer, Geraldine, Gruß, Marco, Köhler, Katja, Brinkmann, Alexander, Fuchs, Thomas, Köberer, Andreas, Geuting, Markus, Weigt, Henry, Baltus, Thomas, Scheltz, Claudia, Bloos, Frank, Reinhart, Konrad, Jegen, Rudolf, Flucht, Marcus, Jürgen, Gburek, Flucht, Marcus, Jegen, Rudolf, Stumm, Anne, Rossenbach, Jannik, Stumm, Anne, Haller, Mathias, Stumm, Anne, Rossenbach, Jannik, Lynch, John, Kempkens, Martin, Buechner, Volkmar, Molitor, Dieter, Klasen, Gerda, Rahmen, Bruno, Muhr, Petra, Canaviri, Patricia, Fiedler, Fritz, Lutz, Jürgen, Kaiser, Marc, Klünter, Simon, Krep, Henning, Anders, Helge, Aduckathil, Sanjay, Sakka, Samir, Reessing, Jan Hinnerk, Aabaid, Sabrina, Löbe, Mathias, Bogatsch, Holger, Löffler, Marcus, Engels, Christoph, Molter, Gerd Peter, Stunz, Michael, Mitrenga, Anja, Geldner, Götz, Bürle, Monica, Klasen, Robert, Werner, Steffanie, Wilhelm, Wolfram, Silke, Frenzel, Juliane, Illert, Jana, Schuttpelz, Briegel, Josef, Möhnle, Patrick, Knorr, Adrian, Hartl, Wolfgang, Ney, Ludwig, Stemmler, Hans-Joachim, Pfister, Hans-Walter, Angstwurm, Matthias, Frey, Lorenz, Irlbeck, Michael, Huge, Volker, Weis, Marion, Kilger, Erich, Hofmann-Kiefer, Klaus, Felbinger, Thomas, Kaufmann, Ines, Goeschl, Julia, Brettner, Franz, Hamm, Heiner, Eife, Claudia, Peckelsen, Claus, Findeisen, Michael, Schmidt-Schridde, Patrick, Kuner, Andreas, Walz, Thomas, Kuner, Barbara, Schrauzer, Thomas, Nentwich, Jens, John, Stefan, Byhahn, Christian, Kretschmer, Thomas, Bergold, Martin N., Weyland, Andreas, Jelschen, Florian, Diers, Anja, Knebel, Frieder G., Kupfer, Thomas, Oppert, Michael, Rohde, Steffen, Möllemann, Angela, Oehmichen, Uwe, Renner, Theresa, Bone, Hans-Georg, Freyhoff, Jörg, Holst, Dana, Birken, Thomas, Henschel, Jörg, Gloger, Martin, Brock, Peter, Klösel, Stephan, Albuszies, Gerd, Schumacher, Detlef, Meierhenrich, Rainer, Schöpp, Alexej, Kuhn, Harald, Riessen, Reimer, Haap, Michael, Ziegler, Silvia, Fastnacht-Böttcher, Jana, Schröder, Rolf Jürgen, Weiss, Manfred, Frank, Katrin, Georgieff, Michael, Weiss, Manfred, Barth, Eberhard, Bracht, Henrik, Ehmcke, Heidrun, Francke, Astrid, Ott, Stefan, Köpcke, Jens, Meyer, Andreas, Jokiel, Gunnar, Freund, Thomas, Schick, Guido, Karassimos, Evagelos, and SepNet Critical Care Trials Group

Published
2017
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10. Deutsche Bearbeitung

Author

Geldner, Götz, primary, Müller-Wolff, Tilmann, additional, Berroth, Ralph, additional, Brinkmann, Alexander, additional, Bürle, Monica, additional, Dewes, Michael, additional, Dubb, Rolf, additional, Franz, Alexander, additional, Frey, Otto, additional, Geldner, Götz, additional, Hafner, Martin, additional, Hermes, Carsten, additional, Hoffmann, Matthias, additional, Kany, Anke, additional, Krause, Franziska, additional, Lichy, Katrin, additional, Lichy, Gregor, additional, Meierhenrich, Rainer, additional, Riessen, Reimer, additional, Röhr, Anka, additional, Rolfes, Caroline, additional, Schäfer, Andreas, additional, Schröder, Torsten, additional, Schwabbauer, Norbert, additional, Spörri, Richard, additional, Träger, Karl, additional, and von Spiegel, Tilman, additional

Published
2017
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11. Komplikationen von 0,9 %iger NaCl-Spüllösungen bei der Thuliumlaserenukleation der Prostata

Author

Graß, Katja, Ghitulescu, Adrian, Geldner, Götz, and Jurczok, Andreas

Abstract

Systemische Flüssigkeitsabsorption tritt bei endoskopischer Prostatachirurgie häufig auf. Mit der Einführung der Lasertherapie in der endoskopischen Prostatachirurgie konnte isotonische und nicht wie bisher nur hypotone Kochsalzlösung verwendet werden. Wir berichten über 2 Patienten, die bei einer Thuliumlaserenukleation (ThuLEP) neben einer isotonischen Hyperhydratation eine hyperchlorämische Azidose entwickelten. Dies führte zu einer Verlängerung der Beatmungszeit, Katecholamin-Pflichtigkeit und zu einem Intensiv- und konsekutiv verlängerten Krankenhausaufenthalt. Eine Umstellung auf balancierte Spüllösungen in der Urologie – wie bereits in der Infusions- und Volumentherapie etabliert – wäre wünschenswert, um v. a. eine hyperchlorämische Azidose zu vermeiden.

Published
2024
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16. Adressen

Author

Hintzenstern, Ulrich v., primary, Arens, Larissa, additional, Bauer, Norbert, additional, Betzenberger, Achim, additional, Cammerer, Ursula, additional, Ebert, Dieter, additional, Erbguth, Frank, additional, Frey, Günter, additional, Gehring, Martin, additional, Haberzeth, Alexander, additional, Heyde, Christoph-E., additional, Hinrichs, Werner, additional, Hintzenstern, Jutta v., additional, Horn, Stephan, additional, Köhnlein, Thomas, additional, Koppenberg, Joachim, additional, Krafft, Tim, additional, Kusche, Dirk, additional, Lehmann, Uwe, additional, Lichy, Gregor, additional, Maleck, Wolfgang H., additional, Maschke, Rolf P., additional, Ochs, Helmut, additional, Reng, Michael, additional, Reuß, Johann, additional, Risack, Dirk, additional, Rossi, Rolando, additional, Rupprecht, Holger, additional, Sasse, Julia, additional, Schaper, Andreas, additional, Schipplick, Martin, additional, Schulz-Drost, Stefan, additional, Sell, Stefan, additional, Strauss, Harald, additional, Ullrich, Odo-Winfried, additional, Weindler, Josef, additional, Weiß, Stefan, additional, von Wietersheim, Hanjo, additional, Wucherer, Michael, additional, Ellinger, Klaus, additional, Feicht, Florian, additional, Fischer, Matthias, additional, Geldner, Götz, additional, Geyer, Karl, additional, Keller, Andreas, additional, Kötter, Katharina, additional, Kretschmer, Rolf, additional, Moecke, Heinzpeter, additional, Neumann, Carsten, additional, Olenik, Daniela, additional, Pohlplatz, Josef, additional, Reinhardt, Thomas, additional, Schulz-Drost, Melanie, additional, Schwalbe, Holger, additional, Sefrin, Peter, additional, Vahrenholt, Jan, additional, Wiesner, Gunther, additional, Wild, Klaus-Joachim, additional, and Wolf, Heinrich, additional

Published
2017
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18. Treatment of spinal anaesthesia-induced hypotension with cafedrine/theodrenaline versus ephedrine during caesarean section

Author

Kranke, Peter, Geldner, Götz, Kienbaum, Peter, Gerbershagen, Hans Jürgen, Chappell, Daniel, Wallenborn, Jan, Huljic, Susanne, Koch, Tilo, Keller, Thomas, Weber, Stephan, Kunitz, Oliver, Linstedt, Ulf, and Eberhart, Leopold H.J.

Subjects
Adult, Ephedrine, Adolescent, Cesarean Section, Phenylpropanolamine, Infant, Newborn, Hypotension, Controlled, Anesthesia, Spinal, Obstetrics, Norepinephrine, Theophylline, Pregnancy, Anesthesia, Obstetrical, Humans, Vasoconstrictor Agents, Female, Prospective Studies, Hypotension
Abstract

BACKGROUND In Germany, hypotension induced by spinal anaesthesia is commonly treated with a combination of cafedrine hydrochloride (C, 200 mg) and theodrenaline hydrochloride (T, 10 mg) in 2 ml. We compared the effectiveness of C/T with ephedrine. OBJECTIVES The primary objectives were to assess the speed of onset and the ability to restore blood pressure without an increase in heart rate. Secondary objectives were to evaluate maternal/foetal outcomes and the number of required additional boluses or other additional measures. DESIGN HYPOTENS was a national, multicentre, prospective, open-label, two-armed, noninterventional study comparing C/T with ephedrine in two prospectively defined cohorts. This study relates to the cohort of patients receiving spinal anaesthesia for caesarean section. SETTING German hospitals using either C/T or ephedrine in their routine clinical practice. PATIENTS Women aged at least 18 years receiving spinal anaesthesia for caesarean section. INTERVENTIONS Bolus administration of C/T or ephedrine at the discretion of the attending anaesthesiologist. MAIN OUTCOME MEASURES Endpoints within 15 min after initial administration of C/T or ephedrine were area under the curve between the observed SBP and the minimum target SBP; and incidence of newly occurring heart rate of at least 100 beats min−1. RESULTS Although effective blood pressure stabilisation was achieved with both treatments, this effect was faster and more pronounced with C/T (P

Published
2021

22. Tipps und Informationen für den Rettungsdienst

Author

Erbguth, Frank, primary, Feicht, Florian, additional, Fischer, Matthias, additional, Frey, Günter, additional, Geldner, Götz, additional, Geyer, Karl, additional, Hintzenstern, Ulrich v., additional, Keller, Andreas, additional, Koppenberg, Joachim, additional, Maschke, Rolf P., additional, Moecke, Heinzpeter, additional, Ochs, Helmut, additional, Reinhardt, Thomas, additional, Schipplick, Martin, additional, Schulz-Drost, Melanie, additional, Strauss, Harald, additional, Vahrenholt, Jan, additional, Weiß, Stefan, additional, Wietersheim, Hanjo v ., additional, and Wolf, Heinrich, additional

Published
2014
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23. Arbeitstechniken

Author

Betzenberger, Achim, primary, Geldner, Götz, additional, Hintzenstern, Ulrich v., additional, Keller, Andreas, additional, Kretschmer, Rolf, additional, Kusche, Dirk, additional, Lichy, Gregor, additional, Maschke, Rolf P., additional, Neumann, Carsten, additional, Pohlplatz, Josef, additional, Reuß, Johann, additional, Sasse, Julia, additional, Schwalbe, Holger, additional, Strauss, Harald, additional, and Vahrenholt, Jan, additional

Published
2014
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24. Analgesie, Sedierung, Narkose, Beatmung, Reanimation

Author

Ellinger, Klaus, primary, Geldner, Götz, additional, Hintzenstern, Ulrich v., additional, Kötter, Katharina, additional, Maleck, Wolfgang H., additional, Olenik, Daniela, additional, Risack, Dirk, additional, and Weiß, Stefan, additional

Published
2014
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25. Adressen

Author

Hintzenstern, Ulrich v., primary, Arens, Larissa, additional, Bauer, Norbert, additional, Betzenberger, Achim, additional, Cammerer, Ursula, additional, Ebert, Dieter, additional, Ellinger, Klaus, additional, Erbguth, Frank, additional, Feicht, Florian, additional, Fischer, Matthias, additional, Frey, Günter, additional, Gehring, Martin, additional, Geldner, Götz, additional, Geyer, Karl, additional, Heyde, Christoph-E., additional, Hinrichs, Werner, additional, Hintzenstern, Jutta v., additional, Horn, Stephan, additional, Keller, Andreas, additional, Köhnlein, Thomas, additional, Kötter, Katharina, additional, Koppenberg, Joachim, additional, Krafft, Tim, additional, Kretschmer, Rolf, additional, Kusche, Dirk, additional, Lehmann, Uwe, additional, Lichy, Gregor, additional, Maleck, Wolfgang H., additional, Maschke, Rolf P., additional, Moecke, Heinzpeter, additional, Neumann, Carsten, additional, Ochs, Helmut, additional, Olenik, Daniela, additional, Pohlplatz, Josef, additional, Reinhardt, Thomas, additional, Reuß, Johann, additional, Risack, Dirk, additional, Rossi, Rolando, additional, Rupprecht, Holger, additional, Sasse, Julia, additional, Schaper, Andreas, additional, Schipplick, Martin, additional, Schulz-Drost, Melanie, additional, Schwalbe, Holger, additional, Sefrin, Peter, additional, Sell, Stefan, additional, Strauss, Harald, additional, Ullrich, Odo-Winfried, additional, Vahrenholt, Jan, additional, Weindler, Josef, additional, Weiß, Stefan, additional, Wiesner, Gunther, additional, Wietersheim, Hanjo von, additional, Wild, Klaus-Joachim, additional, Wolf, Heinrich, additional, Wucherer, Michael, additional, Hetz, Wolfgang, additional, Hintzenstern, Krischan v., additional, Horn, Ina, additional, Koch, Peter, additional, Kögler, Wolfgang, additional, Poppe, Reinhard, additional, and Waitz, Gerhard, additional

Published
2014
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29. Tipps und Informationen für den Rettungsdienst

Author

Erbguth, Frank, primary, Feicht, Florian, additional, Fischer, Matthias, additional, Geldner, Götz, additional, Geyer, Karl, additional, Hintzenstern, Ulrich v., additional, Keller, Andreas, additional, Kögler, Wolfgang, additional, Maschke, Rolf P., additional, Moecke, Heinzpeter, additional, Poppe, Reinhard, additional, Reinhardt, Thomas, additional, Schipplick, Martin, additional, Schulz-Drost, Melanie, additional, Strauss, Harald, additional, Vahrenholt, Jan, additional, Weiß, Stefan, additional, Wietersheim, Hanjo v., additional, and Wolf, Heinrich, additional

Published
2010
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30. Adressen

Author

Hintzenstern, Ulrich v., primary, Arens, Larissa, additional, Bauer, Norbert, additional, Betzenberger, Achim, additional, Cammerer, Ursula, additional, Ebert, Dieter, additional, Ellinger, Klaus, additional, Erbguth, Frank, additional, Feicht, Florian, additional, Fischer, Matthias, additional, Frey, Günter, additional, Gehring, Martin, additional, Geldner, Götz, additional, Geyer, Karl, additional, Hetz, Wolfgang, additional, Heyde, Christoph-E., additional, Hinrichs, Werner, additional, Hintzenstern, Jutta v., additional, Hintzenstern, Krischan v., additional, Horn, Ina, additional, Horn, Stephan, additional, Keller, Andreas, additional, Koch, Peter, additional, Kögler, Wolfgang, additional, Köhnlein, Thomas, additional, Kötter, Katharina, additional, Krafft, Tim, additional, Kretschmer, Rolf, additional, Kusche, Dirk, additional, Lehmann, Uwe, additional, Lichy, Gregor, additional, Maleck, Wolfgang H., additional, Maschke, Rolf P., additional, Moecke, Heinzpeter, additional, Neumann, Carsten, additional, Olenik, Daniela, additional, Pohlplatz, Josef, additional, Poppe, Reinhard, additional, Reinhardt, Thomas, additional, Reuß, Johann, additional, Risack, Dirk, additional, Rossi, Rolando, additional, Rupprecht, Holger, additional, Sasse, Julia, additional, Schaper, Andreas, additional, Schipplick, Martin, additional, Schulz-Drost, Melanie, additional, Sefrin, Peter, additional, Sell, Stefan, additional, Strauss, Harald, additional, Ullrich, Odo-Winfried, additional, Vahrenholt, Jan, additional, Waitz, Gerhard, additional, Weindler, Josef, additional, Weiß, Stefan, additional, Wiesner, Gunther, additional, von Wietersheim, Hanjo, additional, Wild, Klaus-Joachim, additional, Wolf, Heinrich, additional, Wucherer, Michael, additional, Hasenfuß, Stefan, additional, Kreuser, Karl, additional, Plantiko, Peter, additional, Spitzenpfeil, Ernst A., additional, and Welte, Tobias, additional

Published
2010
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31. Analgesie, Sedierung, Narkose, Beatmung, Reanimation

Author

Ellinger, Klaus, primary, Geldner, Götz, additional, Hintzenstern, Ulrich v., additional, Kötter, Katharina, additional, Maleck, Wolfgang H., additional, Olenik, Daniela, additional, Risack, Dirk, additional, and Weiß, Stefan, additional

Published
2010
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32. Arbeitstechniken

Author

Betzenberger, Achim, primary, Geldner, Götz, additional, Hintzenstern, Ulrich v., additional, Keller, Andreas, additional, Koch, Peter, additional, Kretschmer, Rolf, additional, Kusche, Dirk, additional, Lichy, Gregor, additional, Maschke, Rolf P., additional, Neumann, Carsten, additional, Pohlplatz, Josef, additional, Reuß, Johann, additional, Sasse, Julia, additional, Strauss, Harald, additional, and Vahrenholt, Jan, additional

Published
2010
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35. Arbeitstechniken

Author

Betzenberger, Achim, primary, Geldner, Götz, additional, Hasenfuß, Stefan, additional, v. Hintzenstern, Ulrich, additional, Keller, Andreas, additional, Koch, Peter, additional, Kretschmer, Rolf, additional, Kusche, Dirk, additional, Langer, Georg, additional, Maschke, Rolf P., additional, Neumann, Carsten, additional, Pohlplatz, Josef, additional, Sasse, Julia, additional, Strauss, Harald, additional, and Vahrenholt, Jan, additional

Published
2007
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45. Initiale 24-Stunden Intensivstation Glukosewerte sind mit der Entstehung eines zerebralen Vasospasmus nach Subarachnoidalblutung verbunden

Author

Breiding, Philipe Sebastian and Geldner, Götz (Prof. Dr. med.)

Subjects
Medizin, Gesundheit, Vasospasmus, zerebraler Vasospasmus, CVS, Glukose, Subarachnoidalblutung, SAB, Vasospasmus, zerebraler Vasospasmus, Subarachnoidalblutung, SAB, Vasospasm, Cerebral Vasospasm, Glucose, Subarachnoid Haemorrhage, SAH, Medical sciences, Medicine, equipment and supplies, fluids and secretions, ddc:610
Abstract

Der zerebrale Vasospasmus (ZVS) ist eine bekannte Ursache für Morbidität und Mortalität bei Patienten, die an einer Subarachnoidalblutung (SAB) gelitten haben. Seine Entstehung ist mit einer reduzierten zerebralen Perfusion und einer möglichen Entwicklung des neurologischen Defizits verbunden. Die Ätiologie von ZVS hat sich als multifaktoriell erwiesen und es wurden bereits mehrere Risikofaktoren mit seiner Entwicklung verbunden. Da ZVS mit Signalisierungsveränderungen im vaskulären Endothel bereits verknüpft wurde, haben wir die Serumglukose als potentiellen prognostischen Indikator und Risikofaktor, aufgrund ihrer Beziehung zur Endothel-Funktionsstörung gewählt. Ziel dieser Studie war es, die Assoziation zwischen Serum-Glukosespiegel bei SAB-Patienten und der Entwicklung von ZVS zu bewerten. Die retrospektive Studie beinhaltete Daten von Intensivpatienten der Pauls Stradiņš Universitätsklinik mit der primären Diagnose SAB. Wir verglichen die Aufnahme Serum-Glukosespiegel und die Glukosespiegel-Mittelwerte für die ersten 5 Tage auf der Intensivstation bei Patienten mit und ohne anschließende Entwicklung von ZVS. Insgesamt vierundzwanzig Patienten wurden in die Studie aufgenommen. ZVS wurde in 25% (n = 6) bestätigt. Es gab keinen signifikanten Unterschied in der Alters- und Geschlechterverteilung zwischen den Gruppen. Patienten mit ZVS hatten höhere WFNS-Scores (4.80 und 3.56; p=0.008). Wir entdeckten niedrigere Aufnahme-Glukosewerte bei Patienten, die ZVS entwickelten (7.32 und 9.28 mmol/L; p=0.05). Die Glukose-Mittelwerte in den ersten 24 Stunden des Aufenthalts zeigten sich auch niedriger bei Patienten, die ZVS entwickelten (7.26 und 9.29 mmol/L; p=0.03). Es zeigten sich keine signifikanten Unterschiede im durchschnittlichen Glukosespiegel vom 2. bis zum 5. Tag des Aufenthalts. Mortalität wurde durch die Glukosespiegel nicht beeinflusst und die Glukose-Mittelwerte der ersten 24 Stunden korrelierten negativ mit der Dauer des Aufenthalts auf der Intensivstation (rs = -0.408, p, Cerebral vasospasm (CVS) is a well-known cause of morbidity and mortality amongst patients who have suffered from subarachnoid haemorrhage (SAH). Its presence is associated with reduced cerebral perfusion and potential further development of neurological deficit. The aetiology of CVS has been proven to be multifactorial and several risk factors have been associated with its development. Since CVS has been linked to signalling changes in vascular endothelium, serum glucose was chosen as a potential prognostic indicator and risk factor due to its relation with endothelial dysfunction. The objective of this study was to evaluate the association between serum glucose levels in ICU patients admitted with SAH and the development of CVS. The study is a retrospective observational study in which data was collected on patients admitted to the ICU of Pauls Stradiņš Clinical University Hospital with the primary diagnosis of SAH. We compared serum glucose levels on ICU admission and average glucose levels for the first 5 days in the ICU in patients with and without subsequent development of CVS. Twenty-four patients diagnosed with SAH were included in the study. CVS was confirmed in 25% (n=6). There was no significant difference in age and gender distribution between groups. Patients with subsequent development of CVS had higher WFNS score values (4.80 and 3.56; p=0.008). We found lower mean glucose levels on admission for patients that developed CVS compared to those that did not develop CVS (7.32 and 9.28 mmol/L; p=0.05). The average glucose levels on first 24h of ICU stay were also lower in patients who developed CVS (7.26 and 9.29 mmol/L; p=0.03). There were no significant differences in average glucose levels between groups from day 2 to day 5 of ICU stay. Overall mortality was not affected by ICU glucose levels and average glucose levels of first 24h were negatively correlated to the duration of ICU stay (rs = -0.408, p

Published
2017
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47. Pre-operative evaluation of adults undergoing elective noncardiac surgery

Author

De Hert, Stefan, primary, Staender, Sven, additional, Fritsch, Gerhard, additional, Hinkelbein, Jochen, additional, Afshari, Arash, additional, Bettelli, Gabriella, additional, Bock, Matthias, additional, Chew, Michelle S., additional, Coburn, Mark, additional, De Robertis, Edoardo, additional, Drinhaus, Hendrik, additional, Feldheiser, Aarne, additional, Geldner, Götz, additional, Lahner, Daniel, additional, Macas, Andrius, additional, Neuhaus, Christopher, additional, Rauch, Simon, additional, Santos-Ampuero, Maria Angeles, additional, Solca, Maurizio, additional, Tanha, Nima, additional, Traskaite, Vilma, additional, Wagner, Gernot, additional, and Wappler, Frank, additional

Published
2018
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