Search

Your search keyword '"Geit, Werner van"' showing total 9 results
Start Over Author "Geit, Werner van"
9 results on '"Geit, Werner van"'

2. Community-based Reconstruction and Simulation of a Full-scale Model of Region CA1 of Rat Hippocampus

Author

Romani, Armando, primary, Antonietti, Alberto, additional, Bella, Davide, additional, Budd, Julian, additional, Giacalone, Elisabetta, additional, Kurban, Kerem, additional, Sáray, Sára, additional, Abdellah, Marwan, additional, Arnaudon, Alexis, additional, Boci, Elvis, additional, Colangelo, Cristina, additional, Courcol, Jean-Denis, additional, Delemontex, Thomas, additional, Ecker, András, additional, Falck, Joanne, additional, Favreau, Cyrille, additional, Gevaert, Michael, additional, Hernando, Juan B., additional, Herttuainen, Joni, additional, Ivaska, Genrich, additional, Kanari, Lida, additional, Kaufmann, Anna-Kristin, additional, King, James Gonzalo, additional, Kumbhar, Pramod, additional, Lange, Sigrun, additional, Lu, Huanxiang, additional, Lupascu, Carmen Alina, additional, Migliore, Rosanna, additional, Petitjean, Fabien, additional, Planas, Judit, additional, Rai, Pranav, additional, Ramaswamy, Srikanth, additional, Reimann, Michael W., additional, Riquelme, Juan Luis, additional, Guerrero, Nadir Román, additional, Shi, Ying, additional, Sood, Vishal, additional, Sy, Mohameth François, additional, Geit, Werner Van, additional, Vanherpe, Liesbeth, additional, Freund, Tamás F., additional, Mercer, Audrey, additional, Muller, Eilif, additional, Schürmann, Felix, additional, Thomson, Alex M., additional, Migliore, Michele, additional, Káli, Szabolcs, additional, and Markram, Henry, additional

Published
2023
Full Text
View/download PDF

4. Thalamic control of sensory enhancement and sleep spindle properties in a biophysical model of thalamoreticular microcircuitry

Author

Iavarone, Elisabetta, primary, Simko, Jane, additional, Shi, Ying, additional, Bertschy, Marine, additional, García-Amado, María, additional, Litvak, Polina, additional, Kaufmann, Anna-Kristin, additional, O’Reilly, Christian, additional, Amsalem, Oren, additional, Abdellah, Marwan, additional, Chevtchenko, Grigori, additional, Coste, Benoît, additional, Courcol, Jean-Denis, additional, Ecker, András, additional, Favreau, Cyrille, additional, Fleury, Adrien Christian, additional, Geit, Werner Van, additional, Gevaert, Michael, additional, Guerrero, Nadir Román, additional, Herttuainen, Joni, additional, Ivaska, Genrich, additional, Kerrien, Samuel, additional, King, James G., additional, Kumbhar, Pramod, additional, Lurie, Patrycja, additional, Magkanaris, Ioannis, additional, Muddapu, Vignayanandam Ravindernath, additional, Nair, Jayakrishnan, additional, Pereira, Fernando L., additional, Perin, Rodrigo, additional, Petitjean, Fabien, additional, Ranjan, Rajnish, additional, Reimann, Michael, additional, Soltuzu, Liviu, additional, Sy, Mohameth François, additional, Tuncel, M. Anıl, additional, Ulbrich, Alexander, additional, Wolf, Matthias, additional, Clascá, Francisco, additional, Markram, Henry, additional, and Hill, Sean L., additional

Published
2022
Full Text
View/download PDF

5. HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data

Author

Sáray, Sára, primary, Rössert, Christian A., additional, Appukuttan, Shailesh, additional, Migliore, Rosanna, additional, Vitale, Paola, additional, Lupascu, Carmen A., additional, Bologna, Luca L., additional, Geit, Werner Van, additional, Romani, Armando, additional, Davison, Andrew P., additional, Muller, Eilif, additional, Freund, Tamás F., additional, and Káli, Szabolcs, additional

Published
2020
Full Text
View/download PDF

6. Single-neuron models linking electrophysiology, morphology and transcriptomics across cortical cell types

Author

Nandi, Anirban, primary, Chartrand, Tom, additional, Geit, Werner Van, additional, Buchin, Anatoly, additional, Yao, Zizhen, additional, Lee, Soo Yeun, additional, Wei, Yina, additional, Kalmbach, Brian, additional, Lee, Brian, additional, Lein, Ed, additional, Berg, Jim, additional, Sümbül, Uygar, additional, Koch, Christof, additional, Tasic, Bosiljka, additional, and Anastassiou, Costas A., additional

Published
2020
Full Text
View/download PDF

7. Reconstruction and Simulation of Neocortical Microcircuitry

Author

European Commission, Gatsby Charitable Foundation, Ministerio de Economía y Competitividad (España), Hebrew University of Jerusalem, École Polytechnique Fédérale de Lausanne, Swiss National Supercomputing Centre, Swiss National Science Foundation, Office of Naval Research (US), Markram, Henry, Muller, Eilif, Ramaswamy, Srikanth, Reimann, Michael W., Abdellah, Marwan, Aguado Sánchez, Carlos, Ailamaki, Anastasia, Alonso-Nanclares, Lidia, Antille, Nicolas, Arsever, Selim, Atenekeng Kahou, Guy Antoine, Berger, Thomas, Bilgili, Ahmet, Buncic, Nenad, Chalimourda, Athanassia, Chindemi, Giuseppe, Courcol, Jean-Denis, Delalondre, Fabien, Delattre, Vicent, Druckmann, Shaul, Dumusc, Raphael, Dynes, James, Eilemann, Stefan, Gal, Eyal, Gevaert, Michael Emiel, Ghobril, Jean-Pierre, Gidon, Albert, Graham, Joe W., Gupta, Anirudh, Haenel, Valentin, Hay, Etay, Heinis, Thomas, Hernando, Juan B., Hines, Michael, Kanari, Lida, Keller, Daniel, Kenyon, John, Khazen, Georges, Kim, Yihwa, King, James G., Kisvárday, Zoltán F., Kumbhar, Pramod, Lasserre, Sébastien, Le Bé, Jean-Vincent, Magalhães, Bruno R. C., Merchán-Pérez, Ángel, Meystre, Julie, Morrice, Benjamin Roy, Muller, Jeffrey, Muñoz Céspedes, Alberto, Muralidhar, Shruti, Muthurasa, Keerthan, Nachbaur, Daniel, Newton, Taylor H., Nolte, Max, Ovcharenko, Aleksandr, Palacios, Juan, Pastor, Luis, Perin, Rodrigo, Ranjan, Rajnish, Riachi, Imad, Rodríguez, J. Rodrigo, Riquelme, Juan Luis, Rössert, Christian, Sfyrakis, Konstantinos, Shi, Ying, Shillcock, Julian C., Silberberg, Gilad, Silva, Ricardo, Tauheed, Farhan, Telefont, Martin, Toledo-Rodriguez, Maria, Tränkler, Thomas, Geit, Werner van, Villafranca Díaz, Jafet, Walker, Richard, Wang, Yu, Zaninetta, Stefano M., DeFelipe, Javier, Hill, Sean L., Segev, Idan, Schürmann, Felix, European Commission, Gatsby Charitable Foundation, Ministerio de Economía y Competitividad (España), Hebrew University of Jerusalem, École Polytechnique Fédérale de Lausanne, Swiss National Supercomputing Centre, Swiss National Science Foundation, Office of Naval Research (US), Markram, Henry, Muller, Eilif, Ramaswamy, Srikanth, Reimann, Michael W., Abdellah, Marwan, Aguado Sánchez, Carlos, Ailamaki, Anastasia, Alonso-Nanclares, Lidia, Antille, Nicolas, Arsever, Selim, Atenekeng Kahou, Guy Antoine, Berger, Thomas, Bilgili, Ahmet, Buncic, Nenad, Chalimourda, Athanassia, Chindemi, Giuseppe, Courcol, Jean-Denis, Delalondre, Fabien, Delattre, Vicent, Druckmann, Shaul, Dumusc, Raphael, Dynes, James, Eilemann, Stefan, Gal, Eyal, Gevaert, Michael Emiel, Ghobril, Jean-Pierre, Gidon, Albert, Graham, Joe W., Gupta, Anirudh, Haenel, Valentin, Hay, Etay, Heinis, Thomas, Hernando, Juan B., Hines, Michael, Kanari, Lida, Keller, Daniel, Kenyon, John, Khazen, Georges, Kim, Yihwa, King, James G., Kisvárday, Zoltán F., Kumbhar, Pramod, Lasserre, Sébastien, Le Bé, Jean-Vincent, Magalhães, Bruno R. C., Merchán-Pérez, Ángel, Meystre, Julie, Morrice, Benjamin Roy, Muller, Jeffrey, Muñoz Céspedes, Alberto, Muralidhar, Shruti, Muthurasa, Keerthan, Nachbaur, Daniel, Newton, Taylor H., Nolte, Max, Ovcharenko, Aleksandr, Palacios, Juan, Pastor, Luis, Perin, Rodrigo, Ranjan, Rajnish, Riachi, Imad, Rodríguez, J. Rodrigo, Riquelme, Juan Luis, Rössert, Christian, Sfyrakis, Konstantinos, Shi, Ying, Shillcock, Julian C., Silberberg, Gilad, Silva, Ricardo, Tauheed, Farhan, Telefont, Martin, Toledo-Rodriguez, Maria, Tränkler, Thomas, Geit, Werner van, Villafranca Díaz, Jafet, Walker, Richard, Wang, Yu, Zaninetta, Stefano M., DeFelipe, Javier, Hill, Sean L., Segev, Idan, and Schürmann, Felix

Abstract

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of juvenile rat. The reconstruction uses cellular and synaptic organizing principles to algorithmically reconstruct detailed anatomy and physiology from sparse experimental data. An objective anatomical method defines a neocortical volume of 0.29 ± 0.01 mm3 containing ∼31,000 neurons, and patch-clamp studies identify 55 layer-specific morphological and 207 morpho-electrical neuron subtypes. When digitally reconstructed neurons are positioned in the volume and synapse formation is restricted to biological bouton densities and numbers of synapses per connection, their overlapping arbors form ∼8 million connections with ∼37 million synapses. Simulations reproduce an array of in vitro and in vivo experiments without parameter tuning. Additionally, we find a spectrum of network states with a sharp transition from synchronous to asynchronous activity, modulated by physiological mechanisms. The spectrum of network states, dynamically reconfigured around this transition, supports diverse information processing strategies.

Published
2015

9. Associations between in vitro , in vivo and in silico cell classes in mouse primary visual cortex.

Author

Wei Y, Nandi A, Jia X, Siegle JH, Denman D, Lee SY, Buchin A, Geit WV, Mosher CP, Olsen S, and Anastassiou CA

Abstract

The brain consists of many cell classes yet in vivo electrophysiology recordings are typically unable to identify and monitor their activity in the behaving animal. Here, we employed a systematic approach to link cellular, multi-modal in vitro properties from experiments with in vivo recorded units via computational modeling and optotagging experiments. We found two one-channel and six multi-channel clusters in mouse visual cortex with distinct in vivo properties in terms of activity, cortical depth, and behavior. We used biophysical models to map the two one- and the six multi-channel clusters to specific in vitro classes with unique morphology, excitability and conductance properties that explain their distinct extracellular signatures and functional characteristics. These concepts were tested in ground-truth optotagging experiments with two inhibitory classes unveiling distinct in vivo properties. This multi-modal approach presents a powerful way to separate in vivo clusters and infer their cellular properties from first principles.

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results