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2. EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation

3. Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors

4. Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time

5. Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas

6. From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors

7. Identification of potent, selective KDM5 inhibitors

8. Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies

9. Discovery, design, and synthesis of indole-based EZH2 inhibitors

10. Development of methyl isoxazoleazepines as inhibitors of BET

11. An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

12. Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials

13. Corrigendum to “Development of methyl isoxazoleazepines as inhibitors of BET” [Bioorg. Med. Chem. Lett. 25/9 (2015) 1842–1848]

14. Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains

15. A Practical Synthesis of Indoles via a Pd-Catalyzed C–N Ring Formation

16. Studies directed towards the total synthesis of (+)-sieboldine A

17. Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors

18. Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials.

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