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14 results on '"Gee, Allison"'

4. Genes Genomes Genetics / Saccharomyces cerevisiae genes involved in survival of heat shock

Author

Jarolim, Stefanie, Ayer, Anita, Pillay, Bethany, Gee, Allison C., Phrakaysone, Alex, Perrone, Gabriel G., Breitenbach, Michael, and Dawes, Ian W.

Subjects
Saccharomyces_cerevisiae, DNA_repair, heat_shock, tryptophan_metabolism, genome-wide_screen
Abstract

The heat-shock response in cells, involving increased transcription of a specific set of genes in response to a sudden increase in temperature, is a highly conserved biological response occurring in all organisms. Despite considerable attention to the processes activated during heat shock, less is known about the role of genes in survival of a sudden temperature increase. Saccharomyces cerevisiae genes involved in the maintenance of heat-shock resistance in exponential and stationary phase were identified by screening the homozygous diploid deletants in nonessential genes and the heterozygous diploid mutants in essential genes for survival after a sudden shift in temperature from 30 to 50. More than a thousand genes were identified that led to altered sensitivity to heat shock, with little overlap between them and those previously identified to affect thermotolerance. There was also little overlap with genes that are activated or repressed during heat-shock, with only 5% of them regulated by the heat-shock transcription factor. The target of rapamycin and protein kinase A pathways, lipid metabolism, vacuolar H+-ATPase, vacuolar protein sorting, and mitochondrial genome maintenance/translation were critical to maintenance of resistance. Mutants affected in l-tryptophan metabolism were heat-shock resistant in both growth phases; those affected in cytoplasmic ribosome biogenesis and DNA double-strand break repair were resistant in stationary phase, and in mRNA catabolic processes in exponential phase. Mutations affecting mitochondrial genome maintenance were highly represented in sensitive mutants. The cell division transcription factor Swi6p and Hac1p involved in the unfolded protein response also play roles in maintenance of heat-shock resistance.

Published
2013

6. Shoes? Choos!

Author

Miller, Samantha, Corcoran, Liz, Finan, Eileen, Flans, Robyn, and Gee, Allison

Subjects
CHOI, Sandra, JIMMY Choo Ltd.
Abstract

Profiles Sandra Choi, creative director and shoe designer for Jimmy Choo.

Published
2000

7. ON THE BLOCK.

Author

Adkins, Greg, Wren, Jennifer, Gaidatzi, Dimi, Gee, Allison, Howard, Caroline, Keck, William, Nussbaum, Gail, Stueven, Michele, and Tumposky, Ellen

Subjects
CELEBRITIES, SKATERS
Abstract

Olympic superskater Scott Hamilton, 44, and his wife, Tracie Rose Robinson, 33, are starting a family--she's pregnant and due in September 2003. They have put their 4,500-sq.-ft. landmark home in Westlake Village, California on the market while they look for a more traditional house. This estate, built in 1921 and recently renovated by architect Michael Graves, also features three bedrooms, a refitted dock and a party cruise boat.

Published
2003

8. NICOLE'S REVENGE.

Author

Adkins, Greg, Wren, Jennifer, Gaidatzi, Dimi, Gee, Allison, Howard, Caroline, Keck, William, Nussbaum, Gail, Stueven, Michele, and Tumposky, Ellen

Subjects
CELEBRITIES, LEGAL procedure, PERIODICALS
Abstract

After a British tabloid implied that she and actor Jude Law were carrying on an affair, Nicole Kidman sues--and prevails. Angered that Britain's 'Daily Mail' on March 6, 2003 suggested that she was having an adulterous affair with her 'Cold Mountain' costar Jude Law, Kidman not only denied the charge, she sued. The damages will go to aid Romanian orphanages, Kidman's spokeswoman said. Kidman has taken other British publications to task over the same story, including 'The Sunday Telegraph,' which apologized, and 'The Sun,' a dispute still in legal proceedings.

Published
2003

9. Brittany Murphy.

Author

Adkins, Greg, Wren, Jennifer, Gaidatzi, Dimi, Gee, Allison, Howard, Caroline, Keck, William, Nussbaum, Gail, Stueven, Michele, and Tumposky, Ellen

Subjects
ACTRESSES, CELEBRITIES
Abstract

Presents an interview with actress Brittany Murphy. Her love of hip-hop and rap music; How she feels about celebrities such as Drew Barrymore, Angelina Jolie, and Winona Ryder; Consideration of her previous relationship with actor Ashton Kutcher.

Published
2003

10. BEFORE HE WAS COOL.

Author

Adkins, Greg, Wren, Jennifer, Gaidatzi, Dimi, Gee, Allison, Howard, Caroline, Keck, William, Nussbaum, Gail, Stueven, Michele, and Tumposky, Ellen

Subjects
ACTORS, MALE models, MODELS (Persons), CELEBRITIES
Abstract

Mentions how actor Colin Farrell was a model in Australia in 1995. How photographs of Farrell were taken at an abandoned Colgate plant in Sydney, Australia.

Published
2003

11. Teen Triangles.

Author

Adkins, Greg, Wren, Jennifer, Gaidatzi, Dimi, Gee, Allison, Howard, Caroline, Keck, William, Nussbaum, Gail, Stueven, Michele, and Tumposky, Ellen

Subjects
CELEBRITIES, ACTORS, TEENAGERS in motion pictures
Abstract

Provides observations about various teen celebrities such as Lindsay Lohan, Aaron Carter, and Hillary Duff. How Carter was allegedly dating both Lohan and Duff at the same time; Consideration of the relationship between actor Chad Michael Murray and Duff.

Published
2003

12. Harry Potter and the Curse of Puberty.

Author

Adkins, Greg, Wren, Jennifer, Gaidatzi, Dimi, Gee, Allison, Howard, Caroline, Keck, William, Nussbaum, Gail, Stueven, Michele, and Tumposky, Ellen

Subjects
TEENAGERS in motion pictures, ACTORS
Abstract

A photo from the set of next year's eagerly awaited film 'Harry Potter and the Prisoner of Azkaban' suggests that actors Daniel Radcliffe, 14, Emma Watson, 13, and Rupert Grint, 14, though not yet wizened wizards, are growing up fast.

Published
2003

13. Mike Tyson: How I Lost $300 Million.

Author

Adkins, Greg, Wren, Jennifer, Gaidatzi, Dimi, Gee, Allison, Howard, Caroline, Keck, William, Nussbaum, Gail, Stueven, Michele, and Tumposky, Ellen

Subjects
FINANCIAL crises, BANKRUPTCY, CONSUMER credit, PERSONAL finance, BOXERS (Sports)
Abstract

Provides information about the financial distress of heavyweight champion Mike Tyson. How he filed bankruptcy papers on August 1, 2003; His outstanding personal and corporate bills; How Tyson claims that promoter Don King cheated him from $100 million in funds.

Published
2003

14. Saccharomyces cerevisiae genes involved in survival of heat shock.

Author

Jarolim S, Ayer A, Pillay B, Gee AC, Phrakaysone A, Perrone GG, Breitenbach M, and Dawes IW

Subjects
Basic-Leucine Zipper Transcription Factors genetics, Cyclic AMP-Dependent Protein Kinases metabolism, DNA Repair genetics, Gene Expression Regulation, Fungal, Genome, Fungal, Heterozygote, Mutation, Protein Transport, RNA, Messenger metabolism, Repressor Proteins genetics, Reproducibility of Results, Ribosomes genetics, Saccharomyces cerevisiae Proteins metabolism, Telomere, Transcription Factors genetics, Tryptophan genetics, Tryptophan metabolism, Heat-Shock Response genetics, Saccharomyces cerevisiae physiology, Saccharomyces cerevisiae Proteins genetics
Abstract

The heat-shock response in cells, involving increased transcription of a specific set of genes in response to a sudden increase in temperature, is a highly conserved biological response occurring in all organisms. Despite considerable attention to the processes activated during heat shock, less is known about the role of genes in survival of a sudden temperature increase. Saccharomyces cerevisiae genes involved in the maintenance of heat-shock resistance in exponential and stationary phase were identified by screening the homozygous diploid deletants in nonessential genes and the heterozygous diploid mutants in essential genes for survival after a sudden shift in temperature from 30 to 50°. More than a thousand genes were identified that led to altered sensitivity to heat shock, with little overlap between them and those previously identified to affect thermotolerance. There was also little overlap with genes that are activated or repressed during heat-shock, with only 5% of them regulated by the heat-shock transcription factor. The target of rapamycin and protein kinase A pathways, lipid metabolism, vacuolar H(+)-ATPase, vacuolar protein sorting, and mitochondrial genome maintenance/translation were critical to maintenance of resistance. Mutants affected in l-tryptophan metabolism were heat-shock resistant in both growth phases; those affected in cytoplasmic ribosome biogenesis and DNA double-strand break repair were resistant in stationary phase, and in mRNA catabolic processes in exponential phase. Mutations affecting mitochondrial genome maintenance were highly represented in sensitive mutants. The cell division transcription factor Swi6p and Hac1p involved in the unfolded protein response also play roles in maintenance of heat-shock resistance.

Published
2013
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