1. Global and regional burden of chronic respiratory disease in 2016 arising from non-infectious airborne occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016
- Author
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Driscoll T, Steenland K, Pearce N, Rushton L, Hutchings S, Straif K, Abate D, Acharya D, Agrawal A, Alahdab F, Alene K, Androudi S, Anjomshoa M, Antonio C, Aremu O, Ataro Z, Badaw A, Banoub J, Barker-Collo S, Bedi N, Bennett D, Bernstein R, Beuran M, Bhattacharyya K, Bijani A, Butt Z, Carrero J, Castaneda-Orjuela C, Chimed-Ochir O, Dandona L, Dandona R, Dang A, Daryani A, Desalegn B, Dharmaratne S, Djalalinia S, Dubljanin E, Ebrahimpour S, El-Khatib Z, Fareed M, Faro A, Fernandes E, Fischer F, Fukumoto T, Gallus S, Gebremichae T, Gezae K, Grada A, Guo Y, Gupta R, Haj-Mirzaian A, Hamidi S, Hasan M, Hasankhani M, Hay S, Hoang C, Hole M, Hosgood H, Hostiuc M, Hostiuc S, Irvani S, Islam S, Jakovljevic M, Jha R, Jonas J, Kahsay A, Kasaeian A, Kawakami N, Khader Y, Khafaie M, Khan E, Khosravi M, Khubchandani J, Kim Y, Kimokoti R, Kisa A, Kogevinas M, Kosen S, Koul P, Koyanagi A, Defo B, Kumar G, Lal D, Latif A, Leigh J, Levi M, Li S, Linn S, Mahotra N, Majdan M, Malekzadeh R, Mansournia M, Martins-Melo F, Massenburg B, Mehta V, Melese A, Melku M, Memish Z, Mendoza W, Meretoja T, Mestrovic T, Mini G, Mirrakhimov E, Moazen B, Mezerji N, Mohammed S, Mokdad A, Monasta L, Moodley Y, Moosazadeh M, Moradi G, Morawska L, Morrison S, Mousav S, Mustafa G, Nangia V, Nego I, Negoi R, Nguyen C, Nguyen T, Nixon M, Ofori-Asenso R, Ogbo F, Olagunju A, Olusanya B, Mahesh P, Panda-Jonas S, Park E, Pati S, Qorbani M, Rafay A, Rafiei A, Rahim F, Rahimi-Movaghar V, Rajati F, Reiner R, Rezaei S, Roever L, Ronfani L, Roshandel G, Saddik B, Safir S, Sahraian M, Samy A, Schwebel D, Sepanlou S, Serdar B, Shaikh M, Sheikh A, Shigematsu M, Shiri R, Shirkoohi R, Si S, Silva J, Sinha D, Soofi M, Soriano J, Sreeramareddy C, Stanaway J, Stokes M, Sufiyan M, Sutradhar I, Tabares-Seisdedos R, Takahashi K, Tefera Y, Temsah M, Tovani-Palone M, Tran B, Tran K, Car L, Ullah I, Valdez P, van Boven J, Vasankari T, Violante F, Vu G, Wagner G, Waheed Y, Wang Y, Yirsaw B, Yonemoto N, Yu C, Zamani M, Lim S, GBD 2016 Occupational Chronic, Collaborators, GBD 2016 Occupational Chronic Respiratory Risk Factors, GBD 2016 Occupational Chronic Respiratory Risk Factors Collaborator, Violante FS, Groningen Research Institute for Asthma and COPD (GRIAC), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), and Value, Affordability and Sustainability (VALUE)
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pneumoconiosis ,Population ,GBD 2016 occupational chronic respiratory risk factors collaborators ,OBSTRUCTIVE PULMONARY-DISEASE ,Environmental & Occupational Health ,1117 Public Health and Health Services ,03 medical and health sciences ,0302 clinical medicine ,1599 Other Commerce, Management, Tourism and Services ,Environmental health ,METABOLIC RISKS ,Medicine ,COPD ,030212 general & internal medicine ,Workplace ,education ,Public, Environmental & Occupational Health ,Cause of death ,Asthma ,WORK ,education.field_of_study ,Science & Technology ,ONSET ASTHMA ,business.industry ,STATEMENT ,Pneumoconiosis ,Public Health, Environmental and Occupational Health ,1103 Clinical Sciences ,occupational exposure ,medicine.disease ,3. Good health ,Quality-adjusted life year ,PREVALENCE ,occupational asthma ,work ,030228 respiratory system ,Relative risk ,Attributable risk ,COMPARATIVE RISK-ASSESSMENT ,NA ,business ,CLUSTERS ,Life Sciences & Biomedicine ,LUNG - Abstract
ObjectivesThis paper presents detailed analysis of the global and regional burden of chronic respiratory disease arising from occupational airborne exposures, as estimated in the Global Burden of Disease 2016 study.MethodsThe burden of chronic obstructive pulmonary disease (COPD) due to occupational exposure to particulate matter, gases and fumes, and secondhand smoke, and the burden of asthma resulting from occupational exposure to asthmagens, was estimated using the population attributable fraction (PAF), calculated using exposure prevalence and relative risks from the literature. PAFs were applied to the number of deaths and disability-adjusted life years (DALYs) for COPD and asthma. Pneumoconioses were estimated directly from cause of death data. Age-standardised rates were based only on persons aged 15 years and above.ResultsThe estimated PAFs (based on DALYs) were 17% (95% uncertainty interval (UI) 14%–20%) for COPD and 10% (95% UI 9%–11%) for asthma. There were estimated to be 519 000 (95% UI 441,000–609,000) deaths from chronic respiratory disease in 2016 due to occupational airborne risk factors (COPD: 460,100 [95% UI 382,000–551,000]; asthma: 37,600 [95% UI 28,400–47,900]; pneumoconioses: 21,500 [95% UI 17,900–25,400]. The equivalent overall burden estimate was 13.6 million (95% UI 11.9–15.5 million); DALYs (COPD: 10.7 [95% UI 9.0–12.5] million; asthma: 2.3 [95% UI 1.9–2.9] million; pneumoconioses: 0.58 [95% UI 0.46–0.67] million). Rates were highest in males; older persons and mainly in Oceania, Asia and sub-Saharan Africa; and decreased from 1990 to 2016.ConclusionsWorkplace exposures resulting in COPD, asthma and pneumoconiosis continue to be important contributors to the burden of disease in all regions of the world. This should be reducible through improved prevention and control of relevant exposures.
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- 2020