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28 results on '"Gebauer, HJ"'

1. Nachweis einer erfolgreichen Knochenmarkstransplantation 11 Jahre nach Übertragung

Author

Gebauer Hj, Brüster Ht, and Kuntz Bm

Subjects
Transplantation, medicine.medical_specialty, surgical procedures, operative, Bone marrow transplantation, business.industry, medicine, Carcinoma, General Medicine, Human leukocyte antigen, medicine.disease, business, Surgery
Abstract

Bone-marrow transplantation for severe aplastic anaemia was performed in a 14-year-old boy in 1969. The transplanted marrow was not HLA identical: there was HLA-D incompatibility between the female donor and the recipient. The patient had had several blood transfusions and one course of cytostatic conditioning before the transplantation. Six years later he had carcinoma of the colon which was completely removed at surgery. Ten years after transplantation, chimaerism was demonstrated in the recipient who was then haematologically and clinically healthy and in full employment. The bone-marrow transplantation can thus be considered as successful.

Published
2008
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2. Lambda and (Lambda)over-bar polarization from deep in elastic muon scattering

Author

Adams, MR, Aderholz, M, Aid, S, Anthony, PL, Ashery, D, Averill, DA, Baker, MD, Baller, BR, Banerjee, A, Bhatti, AA, Bratzler, U, Braun, HM, Carroll, TJ, Clark, HL, Conrad, JM, Davisson, R, Derado, I, Dietrich, FS, Dougherty, W, Dreyer, T, Eckardt, V, Ecker, U, Erdmann, M, Fang, GY, Figiel, J, Finlay, RW, Gebauer, HJ, Geesaman, DF, Griffioen, KA, Guo, RS, Haas, J, Halliwell, C, Hantke, D, Hicks, KH, Jackson, HE, Jancso, G, Jansen, DM, Jin, Z, Kadija, K, Kaufmann, S, Kennedy, RD, Kinney, ER, Kobrak, HGE, Kotwal, AV, Kunori, S, Lenski, M, Lord, JJ, Lubatti, HJ, McLeod, D, Madden, P, Manz, A, Melanson, H, Michael, DG, Montgomery, HE, Morfin, JG, Nickerson, RB, Novak, J, Olkiewicz, K, Osborne, L, Otten, R, Papavassiliou, V, Pawlik, B, Pipkin, FM, Potterveld, DH, Roser, A, Ryan, JJ, Salgado, CW, Schellman, H, Schmitt, M, Schmitz, N, Siegert, G, Skuja, A, Snow, GA, Soldner-Rembold, S, Spentzouris, P, Stopa, P, Swanson, RA, Pop, VT, Venkataramania, H, Wilhelm, M, Wilson, R, Wittek, W, Wolbers, SA, Zghiche, A, and Zhao, T

Published
2000

3. Nuclear decay following deep inelastic scattering of 470GeV muons (vol 74, pg 5198, 1995)

Author

Adams, MR, Aid, S, Anthony, PL, Averill, DA, Baker, MD, Baller, BR, Banerjee, A, Bhatti, AA, Bratzler, U, Braun, HM, Breidung, H, Busza, W, Carroll, TJ, Clark, HL, Conrad, JM, Davisson, R, Derado, I, Dhawan, SK, Dietrich, FS, Dougherty, W, Dreyer, T, Eckardt, V, Ecker, U, Erdmann, M, Fang, GY, Figiel, J, Finlay, RW, Gebauer, HJ, Geesaman, DF, Griffioen, KA, Guo, RS, Haas, J, Halliwell, C, Hantke, D, Hicks, KH, Hughes, VW, Jackson, HE, Jaffe, DE, Jancso, G, Jansen, DM, Jin, Z, Kaufman, S, Kennedy, RD, Kinney, ER, Kirk, T, Kobrak, HGE, Kotwal, AV, Kunori, S, Lord, JJ, Lubatti, HJ, McLeod, D, Madden, P, Magill, S, Manz, A, Melanson, H, Michael, DG, Montgomery, HE, Morfin, JG, Nickerson, RB, O'Day, S, Olkiewicz, K, Osborne, L, Otten, R, Papavassiliou, V, Pawlik, B, Pipkin, FM, Potterveld, DH, Ramberg, EJ, Roser, A, Ryan, JJ, Salgado, CW, Salvarani, A, Schellman, H, Schmitt, M, Schmitz, N, Schuler, KP, Siegert, G, Skuja, A, Snow, GA, Soldner-Rembold, S, Spentzouris, P, Stier, HE, Stopa, P, Swanson, RA, Venkataramania, H, Wilhelm, M, Wilson, R, Wittek, W, Wolbers, SA, Zghiche, A, Zhao, T, and Collaborat, E

Published
1998

4. Extraction of the Ratio Fn2/Fp2 from Muon-Deuteron and Muon-Proton Scattering at Small x and Q2

Author

Adams, MR, Aïd, S, Anthony, PL, Averill, DA, Baker, MD, Baller, BR, Banerjee, A, Bhatti, AA, Bratzler, U, Braun, HM, Carroll, TJ, Clark, HL, Conrad, JM, Davisson, R, Derado, I, Dhawan, SK, Dietrich, FS, Dougherty, W, Dreyer, T, Eckardt, V, Ecker, U, Erdmann, M, Fang, GY, Figiel, J, Finlay, RW, Gebauer, HJ, Geesaman, DF, Griffioen, KA, Guo, RS, Haas, J, Halliwell, C, Hantke, D, Hicks, KH, Hughes, VW, Jackson, HE, Jaffe, DE, Jancso, G, Jansen, DM, Jin, Z, Kaufman, S, Kennedy, RD, Kinney, ER, Kobrak, HG, Kotwal, AV, Kunori, S, Lord, JJ, Lubatti, HJ, McLeod, D, Madden, P, Magill, S, Manz, A, Melanson, H, Michael, DG, Montgomery, HE, Morfin, JG, Nickerson, RB, Novak, J, O'Day, S, Olkiewicz, K, Osborne, L, Otten, R, Papavassiliou, V, Pawlik, B, and Pipkin, FM

Abstract

The ratio of the deuteron to proton structure functions is measured at very small Bjorken x (down to 10-6) and for Q2>0.001 GeV2 from scattering of 470 GeV muons on liquid hydrogen and deuterium targets. The ratio F2n/F2p extracted from these measurements is found to be constant, at a value of 0.935±0.008±0.034, for x

Published
1995

5. Q2 dependence of the average squared transverse energy of jets in deep-inelastic muon-nucleon scattering with comparison to perturbative QCD predictions

Author

Adams, MR, Arndotïd, S, Anthony, PL, Baker, MD, Bartlett, J, Bhatti, AA, Braun, HM, Busza, W, Conrad, JM, Coutrakon, G, Davisson, R, Derado, I, Dhawan, SK, Dougherty, W, Dreyer, T, Dziunikowska, K, Eckardt, V, Ecker, U, Erdmann, M, Eskreys, A, Figiel, J, Gebauer, HJ, Geesaman, DF, Gilman, R, Green, MC, Haas, J, Halliwell, C, Hanlon, J, Hantke, D, Hughes, VW, Jackson, HE, Jaffe, DE, Jancso, G, Jansen, DM, Kaufman, S, Kennedy, RD, Kirk, T, Kobrak, HG, Krzywdzinski, S, Kunori, S, Lord, JJ, Lubatti, HJ, McLeod, D, Magill, S, Malecki, P, Manz, A, Melanson, H, Michael, DG, Mohr, W, Montgomery, HE, Morfin, JG, Nickerson, RB, O'Day, S, Olkiewicz, K, Osborne, L, Papavassiliou, V, Pawlik, B, Pipkin, FM, Ramberg, EJ, Röser, A, Ryan, JJ, Salgado, CW, Salvarani, A, and Schellman, H

Subjects
High Energy Physics::Phenomenology, High Energy Physics::Experiment, Nuclear Experiment
Abstract

The average squared transverse energy of jets in deep-inelastic muon-nucleon scattering is measured as a function of the momentum transfer squared (Q2), in the range 3

Published
1994

6. STUDY OF PARTICLE SPECTRA WITH AN OPTICALLY READOUT RICH DETECTOR IN THE NA35 EXPERIMENT

Author

BACHLER, J BARTKE, J BIALKOWSKA, H BOCK, R BROCKMANN, R and BUNCIC, P CHASE, SI DERADO, I ECKARDT, V ESCHKE, J and FERENC, D FLEISCHMANN, B FUCHS, M GAZDZICKI, M and GEBAUER, HJ GLADYSZ, E HARRIS, JW HECK, W HOFFMANN, M and KABANA, S KADIJA, K KEIDEL, R KOSIEC, J KOWALSKI, M and KUHMICHEL, A LAHANAS, M LEE, Y LEVINE, M LJUBICIC, A and MARGETIS, S NAPPI, E ODYNIEC, G PAIC, G PANAGIOTOU, AD PETRIDIS, A PFENNIG, J PIPER, A POSA, F and PUHLHOFER, F RAI, G RAUCH, W RENFORDT, R ROHRICH, D and ROTHARD, H RUNGE, K SANDOVAL, A SCHMIDT, E SCHMITZ, N and SCHMOETTEN, E SCHNEIDER, I SEYBOTH, P SEYERLEIN, J and SKRZYPCAK, E STOCK, R STROBELE, H TEITELBAUM, L THOMAS, A TONSE, S VASILEIADIS, G VESZTERGOMBI, G VRANIC, D and WENIG, S and BACHLER, J BARTKE, J BIALKOWSKA, H BOCK, R BROCKMANN, R and BUNCIC, P CHASE, SI DERADO, I ECKARDT, V ESCHKE, J and FERENC, D FLEISCHMANN, B FUCHS, M GAZDZICKI, M and GEBAUER, HJ GLADYSZ, E HARRIS, JW HECK, W HOFFMANN, M and KABANA, S KADIJA, K KEIDEL, R KOSIEC, J KOWALSKI, M and KUHMICHEL, A LAHANAS, M LEE, Y LEVINE, M LJUBICIC, A and MARGETIS, S NAPPI, E ODYNIEC, G PAIC, G PANAGIOTOU, AD PETRIDIS, A PFENNIG, J PIPER, A POSA, F and PUHLHOFER, F RAI, G RAUCH, W RENFORDT, R ROHRICH, D and ROTHARD, H RUNGE, K SANDOVAL, A SCHMIDT, E SCHMITZ, N and SCHMOETTEN, E SCHNEIDER, I SEYBOTH, P SEYERLEIN, J and SKRZYPCAK, E STOCK, R STROBELE, H TEITELBAUM, L THOMAS, A TONSE, S VASILEIADIS, G VESZTERGOMBI, G VRANIC, D and WENIG, S

Abstract

The first identified particle spectra obtained with a proximity focusing RICH detector using an optical readout in the high particle density environment of heavy ion collisions at ultrarelativistic energies are presented. The rapidity and transverse momentum spectra of identified pions, kaons, and protons measured in the reaction S-Au at 200 GeV/nucleon are shown and compared with the predictions of two event generators (Fritiof and VENUS).

Published
1994

7. Gonadoblastom bei einer HY-negativen reinen XY-Gonadendysgenesie

Author

Dolff M, Freundl G, and Gebauer Hj

Subjects
endocrine system, medicine.medical_specialty, medicine.drug_class, Obstetrics and Gynecology, Gonadoblastoma, Tall Stature, Karyotype, Biology, medicine.disease, XY gonadal dysgenesis, Dysgenesis, Endocrinology, Estrogen, Cell culture, Internal medicine, Maternity and Midwifery, medicine, Testosterone
Abstract

A case is reported of a gonadoblastoma in a pure XY-gonadal dysgenesis which was HY antigen negative. The salient clinical features were amenorrhoea and tall stature. The FSH was markedly increased, combined with low E2 and testosterone values. Cytogenetically a 46-XY karyotype was found. The HY antigen titre was in a male level. The gonadal streaks which were removed showed microscopically islands of tumour cells with 2 cell lines which were interpreted as germ cells and granulosa cells. Newer concepts of the influence of the HY antigen on the differentiation of the testicles and differentiation of the ovaries are discussed. Treatment consists of removal of the gonadal streaks and estrogen treatment.

Published
1980
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8. MULTIPLICITY AND TRANSVERSE ENERGY FLUX IN O-16+PB AT 200 GEV PER NUCLEON

Author

BAMBERGER, A BANGERT, D BARTKE, J BIALKOWSKA, H BOCK, R and BROCKMANN, R DEMARZO, C DEPALMA, M DERADO, I and ECKARDT, V FAVUZZI, C FENT, J FERENC, D FESSLER, H and FREUND, P GAZDZICKI, M GEBAUER, HJ GEISSLER, K GUERRA, C and HARRIS, JW HECK, W HUMANIC, T KADIJA, K KEIDEL, R and KOWALSKI, M MARGETIS, S NAPPI, E ODYNIEC, G PAIC, G and PANAGIOTOU, AD PETRIDIS, A PFENNIG, J POSA, F and PRETZL, KP PUGH, HG PUHLHOFER, F RAI, G RANIERI, A and RENFORDT, R ROHRICH, D RUNGE, K SANDOVAL, A SCHALL, D and SCHMITZ, N SCHROEDER, LS SELVAGGI, G SEYBOTH, P and SEYERLEIN, J SKRZYPCZAK, E SPINELLI, P STOCK, R and STROBELE, H THOMAS, A TINCKNELL, M TEITELBAUM, L and VESZTERGOMBI, G VRANIC, D WENIG, S WENSVEEN, M

Published
1987

9. CHARGED-PARTICLE MULTIPLICITIES AND INELASTIC CROSS-SECTIONS IN HIGH-ENERGY NUCLEAR COLLISIONS

Author

BAMBERGER, A BANGERT, D BARTKE, J BIALKOWSKA, H BOCK, R and BROCKMANN, R CHASE, SI DEMARZO, C DEPALMA, M DERADO, I ECKARDT, V FAVUZZI, C FENT, J FERENC, D FESSLER, H and FREUND, P GAZDZICKI, M GEBAUER, HJ GEISSLER, K and GLADYSZ, E GUERRA, C HARRIS, JW HECK, W HUMANIC, T and KADIJA, K KARABARBOUNIS, A KEIDEL, R KOSIEC, J KOWALSKI, M MARGETIS, S NAPPI, E ODYNIEC, G PAIC, G and PANAGIOTOU, AD PETRIDIS, A PFENNIG, J POSA, F PRETZL, KP and PUGH, HG PUHLHOFER, F RAI, G RANIERI, A RAUCH, W and RENFORDT, R ROHRICH, D RUNGE, K SANDOVAL, A SCHALL, D and SCHMITZ, N SCHROEDER, LS SELVAGGI, G SEYBOTH, P and SEYERLEIN, J SKRZYPCZAK, E SPINELLI, P STOCK, R and STROBELE, H THOMAS, A TINCKNELL, M TEITELBAUM, L and VESZTERGOMBI, G VRANIC, D WENIG, S

Published
1988

10. PROBING THE SPACE-TIME GEOMETRY OF ULTRA-RELATIVISTIC HEAVY-ION COLLISIONS

Author

BAMBERGER, A BANGERT, D BARTKE, J BIALKOWSKA, H BOCK, R and BROCKMANN, R CHASE, SI DEMARZO, C DEPALMA, M DERADO, I ECKARDT, V FAVUZZI, C FENT, J FERENC, D FESSLER, H and FREUND, P GAZDZICKI, M GEBAUER, HJ GEISSLER, K and GLADYSZ, E GUERRA, C HARRIS, JW HECK, W HUMANIC, TJ and KADIJA, K KARABARBOUNIS, A KEIDEL, R KOSIEC, J KOWALSKI, M MARGETIS, S NAPPI, E ODYNIEC, G PAIC, G and PANAGIOTOU, A PETRIDIS, A PFENNIG, J POSA, F PRETZL, KP and PUGH, HG PUHLHOFER, F RAI, G RANIERI, A RAUCH, W and RENFORDT, R ROHRICH, D RUNGE, K SANDOVAL, A SCHALL, D and SCHMITZ, N SCHROEDER, LS SELVAGGI, G SEYBOTH, P and SEYERLEIN, J SKRZYPCZAK, E SPINELLI, P STOCK, R and STROBELE, H THOMAS, A TINCKNELL, M TEITELBAUM, L and VESZTERGOMBI, G VRANIC, D WENIG, S

Published
1988

11. Proton and deuteron structure functions in muon scattering at 470 GeV.

Author

Adams MR, Aïd S, Anthony PL, Averill DA, Baker MD, Baller BR, Banerjee A, Bhatti AA, Bratzler U, Braun HM, Carroll TJ, Clark HL, Conrad JM, Davisson R, Derado I I, Dietrich FS, Dougherty W, Dreyer T, Eckardt V V, Ecker U, Erdmann M, Fang GY, Figiel J, Finlay RW, Gebauer HJ, Geesaman DF, Griffioen KA, Guo RS, Haas J, Halliwell C, Hantke D, Hicks KH, Jackson HE, Jaffe DE, Jancso G, Jansen DM, Jin Z, Kaufman S, Kennedy RD, Kinney ER, Kobrak HG, Kotwal AV, Kunori S, Lord JJ, Lubatti HJ, McLeod D, Madden P, Magill S, Manz A, Melanson H, Michael DG, Montgomery HE, Morfin JG, Nickerson RB, Novak J, O'Day S, Olkiewicz K, Osborne L, Otten R, Papavassiliou V V, Pawlik B, Pipkin FM, Potterveld DH, and Ramberg EJ

Published
1996
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12. Nuclear decay following deep inelastic scattering of 470 GeV muons.

Author

Adams MR, Aïd S, Anthony PL, Averill DA, Baker MD, Baller BR, Banerjee A, Bhatti AA, Bratzler U, Braun HM, Breidung H, Busza W, Carroll TJ, Clark HL, Conrad JM, Davisson R, Derado I I, Dhawan SK, Dietrich FS, Dougherty W, Dreyer T, Eckardt V V, Ecker U, Erdmann M, Fang GY, Figiel J, Finlay RW, Gebauer HJ, Geesaman DF, Griffioen KA, Guo RS, Haas J, Halliwell C, Hantke D, Hicks KH, Hughes VW, Jackson HE, Jaffe DE, Jancso G, Jansen DM, Jin Z, Kaufman S, Kennedy RD, Kinney ER, Kirk T, Kobrak HG, Kotwal AV, Kunori S, Lord JJ, Lubatti HJ, McLeod D, Madden P, Magill S, Manz A, Melanson H, Michael DG, Montgomery HE, Morfin JG, Nickerson RB, O'Day S, Olkiewicz K, Osborne L, Otten R, and Papavassiliou V V

Published
1995
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13. Measurement of nuclear transparencies from exclusive rho 0 meson production in muon-nucleus scattering at 470 GeV.

Author

Adams MR, Aïd S, Anthony PL, Averill DA, Baker MD, Baller BR, Banerjee A, Bhatti AA, Bratzler U, Braun HM, Breidung H, Busza W, Carroll TJ, Clark HL, Conrad JM, Davisson R, Derado I I, Dhawan SK, Dietrich FS, Dougherty W, Dreyer T, Eckardt V V, Ecker U, Erdmann M, Faller F, Fang GY, Figiel J, Finlay RW, Gebauer HJ, Geesaman DF, Griffioen KA, Guo RS, Haas J, Halliwell C, Hantke D, Hicks KH, Hughes VW, Jackson HE, Jancso G, Jansen DM, Jin Z, Kaufman S, Kennedy RD, Kinney ER, Kirk T, Kobrak HG, Kotwal AV, Kunori S, Lancaster S, Lord JJ, Lubatti HJ, McLeod D, Madden P, Magill S, Manz A, Melanson H, Michael DG, Montgomery HE, Morfin JG, Nickerson RB, O'Day S, Olkiewicz K, Osborne L, and Otten R

Published
1995
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14. Scaled energy (z) distributions of charged hadrons observed in deep-inelastic muon scattering at 490 GeV from xenon and deuterium targets.

Author

Adams MR, Aïd S, Anthony PL, Baker MD, Bartlett J, Bhatti AA, Braun HM, Busza W, Carroll T, Conrad JM, Coutrakon G, Davisson R, Derado I I, Dhawan SK, Dougherty W, Dreyer T, Dziunikowska K, Eckardt V V, Ecker U, Erdmann M, Eskreys A, Figiel J, Gebauer HJ, Geesaman DF, Gilman R, Green MC, Haas J, Halliwell C, Hanlon J, Hantke D, Hughes VW, Jackson HE, Jaffe DE, Jancso G, Jansen DM, Kaufman S, Kennedy RD, Kirk T, Kobrak HG, Krzywdzinski S, Kunori S, Lord JJ, Lubatti HJ, McLeod D, Magill S, Malecki P, Manz A, Melanson H, Michael DG, Mohr W, Montgomery HE, Morfin JG, Nickerson RB, O'Day S, Olkiewicz K, Osborne L, Papavassiliou V V, Pawlik B, Pipkin FM, Ramberg EJ, Röser A, Ryan JJ, Salvarani A, and Schellman H

Published
1994
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15. Perturbative QCD effects observed in 490 GeV deep-inelastic muon scattering.

Author

Adams MR, Aïd S, Anthony PL, Baker MD, Bartlett J, Bhatti AA, Braun HM, Busza W, Conrad JM, Coutrakon G, Davisson R, Derado I I, Dhawan SK, Dougherty W, Dreyer T, Dziunikowska K, Eckardt V V, Ecker U, Erdmann M, Eskreys A, Figiel J, Gebauer HJ, Geesaman DF, Gilman R, Green MC, Haas J, Halliwell C, Hanlon J, Hantke D, Hughes VW, Jackson HE, Jaffe DE, Jancso G, Jansen DM, Kaufman S, Kennedy RD, Kirk T, Kobrak HG, Krzywdzinski S, Kunori S, Lord JJ, Lubatti HJ, McLeod D, Magill S, Malecki P, Manz A, Melanson H, Michael DG, Mohr W, Montgomery HE, Morfin JG, Nickerson RB, O'Day S, Olkiewicz K, Osborne L, Papavassiliou V V, Pawlik B, Pipkin FM, Ramberg EJ, Röser A, Ryan JJ, Salgado CW, Salvarani A, and Schellman H

Published
1993
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16. First measurements of jet production rates in deep-inelastic lepton-proton scattering.

Author

Adams MR, Aïd S, Anthony PL, Baker MD, Bartlett J, Bhatti AA, Braun HM, Busza W, Conrad JM, Coutrakon G, Davisson R, Derado I I, Dhawan SK, Dougherty W, Dreyer T, Dziunikowska K, Eckardt V V, Ecker U, Erdmann M, Eskreys A, Figiel J, Gebauer HJ, Geesaman DF, Gilman R, Green MC, Haas J, Halliwell C, Hanlon J, Hantke D, Hughes VW, Jackson HE, Jaffe DE, Jancso G, Jansen DM, Kaufman S, Kennedy RD, Kobrak HG, Krzywdzinski S, Kunori S, Lord JJ, Lubatti HJ, McLeod D, Magill S, Malecki P, Manz A, Michael DG, Mohr W, Montgomery HE, Morfin JG, Nickerson RB, O'Day S, Olkiewicz K, Osborne L, Papavassiliou V V, Pawlik B, Pipkin FM, Ramberg EJ, Röser A, Ryan J, Salgado CW, Salvarani A, Schellman H, Schmitz N, and Schüler KP

Published
1992
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17. Saturation of shadowing at very low Bjorken x.

Author

Adams MR, Aïd S, Anthony PL, Baker MD, Bartlett J, Bhatti AA, Braun HM, Busza W, Carroll TJ, Conrad JM, Coutrakon G, Davisson R, Derado I I, Dhawan SK, Dougherty W, Dreyer T, Dziunikowska K, Eckardt V V, Ecker U, Erdmann M, Eskreys A, Figiel J, Gebauer HJ, Geesaman DF, Gilman R, Green MC, Haas J, Halliwell C, Hanlon J, Hantke D, Hughes VW, Jackson HE, Jaffe DE, Jancso G, Jansen DM, Kaufman S, Kennedy RD, Kirk T, Kobrak HG, Krzywdzinski S, Kunori S, Lord JJ, Lubatti HJ, McLeod D, Magill S, Malecki P, Manz A, Melanson H, Michael DG, Mohr W, Montgomery HE, Morfin JG, Nickerson RB, O'Day S, Olkiewicz K, Osborne L, Papavassiliou V V, Pawlik B, Pipkin FM, Ramberg EJ, Röser A, Ryan JJ, Salvarani A, and Schellman H

Published
1992
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18. Cytogenetic effects during extracorporeal photopheresis treatment of two patients with cutaneous T-cell lymphoma.

Author

Peterseim UM, Küster W, Gebauer HJ, Meschig R, and Plewig G

Subjects
Administration, Oral, Aged, Chromosome Aberrations, Female, Humans, Lymphocytes drug effects, Lymphocytes pathology, Lymphocytes ultrastructure, Lymphoma, T-Cell, Cutaneous genetics, Male, Methoxsalen pharmacology, Middle Aged, Mitosis, Mutation genetics, Phytohemagglutinins pharmacology, Sister Chromatid Exchange, Skin Neoplasms genetics, Tumor Cells, Cultured drug effects, Tumor Cells, Cultured pathology, Lymphoma, T-Cell, Cutaneous therapy, Methoxsalen administration & dosage, Phototherapy methods, Skin Neoplasms therapy
Abstract

The effect of extracorporeal photopheresis (EP) on various cytogenetic parameters has been investigated. During EP the photoactivatable agent 8-methoxypsoralen (8-MOP) was administered orally. After 2 h a leukocyte-enriched blood fraction was collected by haemocentrifugation, irradiated with UVA extracorporeally, and reinfused to the patient. Two patients suffering from cutaneous T-cell lymphoma showed a marked clinical improvement in response to therapy. In order to investigate the cytogenetic effects and mutagenic risk of EP, the mitotic index (MI), the type and number of chromosomal aberrations and the rate of sister chromatid exchanges (SCE) were studied. Following EP treatment the patients' lymphocytes were cultured and stimulated with phytohaemagglutinin (PHA) for 48 or 72 h. The cultured lymphocytes showed a decreased MI after 48 h as an indicator of cytotoxic effects, but not after 72 h. In lymphocyte cultures not stimulated with PHA, the MI was decreased even after 72 h. The number of chromosomal aberrations and SCE were increased upon treatment, but only transiently, returning to basal levels between consecutive treatments. Our data provides no evidence for increased mutagenic risk as a consequence of effective EP treatment.

Published
1991
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19. [Familial nystagmus and hypoplasia of the macular in reciprocal, balanced translocation 5/16].

Author

Hammerstein W and Gebauer HJ

Subjects
Adult, Child, Child, Preschool, Female, Humans, Middle Aged, Pedigree, Chromosomes, Human, Pair 16, Chromosomes, Human, Pair 5, Macula Lutea abnormalities, Nystagmus, Pathologic genetics, Translocation, Genetic genetics
Abstract

We observed three patients with nystagmus and hypoplasia of the macula. The patients had a translocation of 5/16.

Published
1989

20. [Syndrome of blue sclerae and keratoglobus (ocular type of Ehlers-Danlos syndrome (author's transl)].

Author

Behrens-Baumann W, Gebauer HJ, and Langenbeck U

Subjects
Child, Consanguinity, Cornea, Diagnosis, Differential, Ehlers-Danlos Syndrome genetics, Eye Diseases genetics, Female, Humans, Keratoconus diagnosis, Pedigree, Sclera, Ehlers-Danlos Syndrome diagnosis, Eye Manifestations
Abstract

Two children born on Crete of consanguinous parents presented the following manifestations of the ocular type of Ehlers-Danlos syndrome (EDS): blue sclerae, keratoglobus and rupture of cornea following minor trauma. In cultivated fibroblasts of one of the patients there was no evidence of defective lysine hydroxylation. The possible relation of our case to a recent similar report by Judisch et al. (1976) is discussed. The ocular type of EDS may be genetically heterogenous. Provisionally, we propose for cases with normal lysyl hydroxylation in vitro the term 'type VIII of EDS'.

Published
1977
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21. Cardiac defects in chromosomally abnormal human embryos of 10-14 weeks' gestation.

Author

Coerdt W, Rehder H, Gebauer HJ, Holzgreve W, Klink F, Miny P, and Schulze B

Subjects
Adult, Chromosome Disorders, Female, Gestational Age, Heart Defects, Congenital pathology, Humans, Male, Maternal Age, Middle Aged, Polyploidy, Pregnancy, High-Risk, Chromosome Aberrations pathology, Chromosomes, Human, Pair 18, Down Syndrome pathology, Heart Defects, Congenital genetics, Trisomy
Abstract

Cardiac defects were studied in five chromosomally abnormal embryos of 10-14 weeks' gestation by free-hand microdissection of hearts measuring 2.5-6 mm in diameter. The type of cardiac malformation alone or in association with other anomalies helped to confirm the chromosome diagnosis established prenatally by chorionic villus sampling or after spontaneous abortion. It was suggestive of a chromosomal disorder in one case in which cytogenetic investigation had failed.

Published
1988
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22. Cri-du-chat syndrome in a child with a 5/15 translocation and interstitial centromeric heterochromatin.

Author

Gebauer HJ, Stumpf B, Hansmann I, and Grimm T

Subjects
Chromosome Banding, Female, Humans, Infant, Staining and Labeling, Centromere ultrastructure, Chromosomes ultrastructure, Chromosomes, Human, 13-15, Chromosomes, Human, 4-5, Cri-du-Chat Syndrome genetics, Heterochromatin ultrastructure, Translocation, Genetic
Abstract

A child is described with most of the typical clinical features of the cri-du-chat syndrome. G- and C-banding studies revealed the karyotype 45,XX, -5, -15, +tdic (5;15) with the loss of short arm material from chromosome 5. Centromeric heterochromatin of the translocated No. 15 is still present in the translocation chromosome. However, no silver precipitation after AgNO3-staining was observed on the translocation chromosome, thus indicating a loss or genetic inactivation of the NOR-region of the translocated No. 15. These cytogenetic results and their possible relationship to the cri-du-chat phenotype are discussed.

Published
1978
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23. [Triploidy in newborn infants].

Author

Küster W, Beckmann H, Gebauer HJ, and Majewski F

Subjects
Chromosome Disorders, Female, Humans, Infant, Newborn, Karyotyping, Syndactyly genetics, Abnormalities, Multiple genetics, Chromosome Aberrations genetics, Ploidies
Abstract

Human triploidy, a common condition occurring in about 1 to 2% of all clinically recognizable pregnancies, is a rare finding in live-born children. Not more than 44 live-born triploid infants have been reported in the available literature. Triploid infants surviving for more than a few days have been suspected to be hidden mosaicisms and mostly have turned out to be diploid-triploid mosaics. We observed two live-born female infants with a complete triploidy and describe the typical clinical picture.

Published
1988

24. [Granulocyte function defects, chromosome anomalies and blood group chimerism in 2 sisters with familial aplastic anemia (Estren-Dameshek type)].

Author

Ebell W, Wahn V, Gebauer HJ, Kuntz B, Arnoldussen G, and Göbel U

Subjects
Adolescent, Anemia, Aplastic complications, Bacterial Infections complications, Chemotaxis, Child, Chimera, Chromosome Disorders, Female, Humans, Phagocytosis, Anemia, Aplastic genetics, Blood Group Antigens, Chromosome Aberrations complications, Granulocytes pathology
Published
1983
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25. Possible origin of a small bisatellited additional chromosome.

Author

Bartsch HD, de Azevedo Moreira LM, Röhrborn G, Claussen U, and Gebauer HJ

Subjects
Chromosome Banding, Chromosomes, Human, 13-15, Chromosomes, Human, 21-22 and Y, Female, Genetic Markers, Humans, Karyotyping, Male, Pedigree, Pregnancy, Prenatal Diagnosis, Silver Nitrate, Chromosome Aberrations
Abstract

The possible derivation of a small supernumerary marker chromosome was investigated by means of different staining techniques and the frequency of satellite associations. It could be demonstrated that the marker chromosome participates at satellite association more than randomly. The marker chromosome is supposed to derive from 2 of chromosomes 13, 14, 21, or 22.

Published
1980
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26. [Partial deletion of the short arm of chromosome 13 as an indication of paternity in forensic assessment].

Author

Gebauer HJ, Scheil HG, and Röhrborn G

Subjects
Adult, Child, Chromosome Banding, Female, Humans, Male, Polymorphism, Genetic, Chromosome Deletion, Chromosomes, Human, Pair 13, Paternity
Abstract

We report a paternity testing case in which a decisive clue was a deletion of the short arm of chromosome 13 in the child and in his putative father.

Published
1988
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27. Report of a deletion 11 (qter----q23.3) and short review of the literature.

Author

Küster W, Gebauer HJ, Majewski F, and Lenard HG

Subjects
Body Height, Child, Chromosome Banding, Facial Expression, Humans, Karyotyping, Lymphocytes ultrastructure, Male, Chromosome Deletion, Chromosomes, Human, 6-12 and X, Intellectual Disability genetics
Abstract

A male child is described with short stature, mental retardation and unusual facial appearance. Cytogenetic analysis revealed a partial deletion of the long arm of chromosome 11: 46,XY,del (11)(qter----q23.3:). A short review of previously reported cases of del 11q is presented. A comparison of the main clinical characteristics and the extent of the 11q deletion is given.

Published
1985
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