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Introduction: Coronary artery disease (CAD) is a prevalent comorbidity among patients undergoing lung cancer surgery, posing significant perioperative challenges. Video-assisted thoracoscopic surgery (VATS) has gained prominence for its minimally invasive approach and reduced morbidity compared to open thoracotomy. This study investigates the outcomes of VATS in patients with non-small cell lung cancer (NSCLC) and concomitant CAD. Materials and Methods: This retrospective study analyzed 42 patients with NSCLC who underwent VATS anatomical resections at Kartal Kosuyolu High Specialization Education & Research Hospital from April 2020 to August 2024. Patients were divided into two groups: the study group included those with a history of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), while the control group comprised patients without such histories. All patients underwent preoperative cardiac evaluations and tailored antithrombotic management. Outcomes were assessed in terms of perioperative complications, postoperative recovery, and pathological findings. Results: The study group (n=20) and control group (n=22) were comparable in terms of demographics and tumor characteristics. The mean operative time was 312 minutes for the study group and 330 minutes for the control group. Drain removal time and hospital stay were slightly longer in the study group. Postoperative cardiovascular complications were minimal, with no significant differences between groups. Pathological evaluation revealed similar tumor histology and staging, predominantly adenocarcinoma in both groups. VATS demonstrated low conversion rates and acceptable outcomes, even in high-risk patients with CAD. Conclusion: VATS is a feasible and safe surgical option for NSCLC patients with concomitant CAD. With appropriate preoperative evaluations and individualized management, perioperative risks can be minimized, enabling effective surgical treatment for this complex patient population. [ABSTRACT FROM AUTHOR] more...

Atypical radiologic and clinical patterns may be observed within subgroups of lung adenocarcinoma. A 74-year-old man with progressive dyspnea and productive cough unresponsive to antibiotherapy showed bilateral interstitial changes in the lung parenchyma on computed tomography. We here report a patient followed up with a prediagnosis of interstitial lung disease but eventually diagnosed with lung adenocarcinoma following transthoracic lung biopsy. [ABSTRACT FROM AUTHOR] more...

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Objective: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is increasingly used to sample mediastinal lymph nodes and lesions. However, the methodological details of an optimal preparation technique for aspirated material have not yet been clearly determined. This study was an evaluation of the effect of 2 preparation techniques on the adequacy of aspirated specimens. Material and Method: A retrospective analysis was performed of EBUS-TBNA samples obtained at the institution over a total of 36 months. Two periods were examined. Almost all of the aspirated material was smeared onto slides and fixed with 95% alcohol in the first period of the study. Subsequently, to improve diagnostic ability, a pair of slides was prepared from each needle pass: the first was air-dried, and the second was fixed in 95% alcohol. The remainder of the aspirate was kept for cell block analysis. Results: In total, 462 samples were obtained from 260 patients. The overall sampling adequacy was 74% in the first and 81.1% in the second period (p<0.05). Approximately 14% of the specimens included a sufficient number of cells for immunohistochemical cell block evaluation in the first period and 42% in the second period (p<0.001). Histological subtyping of non-small cell lung carcinoma was determined in 18 (56.3%) and the primary origin of a tumor was determined based on morphological and immunohistochemical properties in 32 (84.2%) of the patients in the first and second periods, respectively. Conclusion: The access to a sufficient EBUS-TBNA sample and the ability to perform the appropriate preparation can impact the specific diagnosis and treatment of patient with a single procedure. [ABSTRACT FROM AUTHOR] more...

Objective: This study has been conducted so as to contribute to health statistics of hydatid cyst by the data obtained from our clinic, and to discuss hydatid cysts in unusual locations. Material and Method: Cases diagnosed as hydatid cyst at Dr. Lutfi Kirdar Kartal Research and Education Hospital Pathology Clinic between 2007 and 2015 have been evaluated based on criteria such as age, sex and location. Results: A total of 364 cases, 209 females and 155 males, have been included in the study. The subjects in the cases are aged between 4 and 81 (mean: 38.84). Regarding the sites, 254 (69.8%) of the cases are located in liver, and 53 (14.6%) in the lung. Fifty-seven cases (15.6%) have been detected in unusual sites other than the lung or liver. The rate of isolated organ involvement, other than the lung and liver, has been found to be 10.3%. Conclusion: Since hydatid cyst can be found in all the body sites, it should be taken into account in the differential diagnosis of all cystic lesions. [ABSTRACT FROM AUTHOR] more...

The article presents transthoracic echocardiogram (TTE) and transesophageal echocardiography (TEE) images that illustrate the unusual coexistence of atrial myxoma and mitral stenosis in a 22-year-old woman with a history of transient ischemic attack. more...

Background: This study aims to evaluate the factors influencing the adequacy of endobronchial ultrasound-guided transbronchial fine needle aspiration specimens., Methods: A retrospective analysis of 1,700 endobronchial ultrasound-guided transbronchial fine needle aspiration samples obtained from 822 patients (500 males, 322 females; mean age 56±13 years; range 16 to 83 years) was performed between March 2011 and March 2014 at our center. Variables potentially associated with sampling adequacy, such as all cytological materials and procedure notes (lymph node and/or lesion size, localization, needle pass number, and slide number) were examined., Results: The overall specimen adequacy was 79.8%. The specimen adequacy was associated with needle pass number (p≤0.001). Adequacy rate was 66.9% for one needle pass and 85.8% for three needle passes. According to the sampling regions, adequacy rates showed a difference [69.2%-85.8%; (p≤0.005)]. In the multivariate logistic regression analysis of subcarinal (7) lymph node station, patient age (odds ratio, 0.983; 95% confidence interval, 0.966-1.000; p=0.049) and number of slides (odds ratio, 1.240; 95% confidence interval, 1.062-1.448; p=0.006) were independent determining factors of specimen adequacy. While independent determinants of specimen adequacy for the right paratracheal (4R) region were lymph node size (odds ratio, 1.486; 95% confidence interval, 0.973-2.268; p=0.067) and number of slides (odds ratio, 1.418; 95% confidence interval, 1.146-1.756; p=0.001), they were lymph node size (odds ratio, 1.594; 95% confidence interval, 0.960-2.645; p=0.071) and number of needle passes (odds ratio, 2.277; 95% confidence interval, 1.360-3.811; p=0.002) for the right interlobar (11R) region. Independent determinant of specimen adequacy for the left paratracheal (4L) lymph node station was the number of needle passes (odds ratio, 1.656; 95% confidence interval, 0.955-2.869; p=0.072)., Conclusion: During endobronchial ultrasound-guided transbronchial fine needle aspirations, particularly when rapid on site evaluation cannot be applied, consideration of factors affecting adequacy according to lymph node localizations may increase the chance for obtaining materials with suitable quality for cytologic evaluation., Competing Interests: Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article., (Copyright © 2018, Turkish Society of Cardiovascular Surgery.) more...