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47 results on '"Gaznabi, Safwan"'

7. Multimodality Imaging in Aortic Stenosis

Author

Gaznabi, Safwan, Miranda, Jeirym, Lorenzatti, Daniel, Piña, Pamela, Balasubramanian, Senthil S., Desai, Darshi, Desai, Aditya, Ho, Edwin C., Scotti, Andrea, Gongora, Carlos A., Schenone, Aldo L., Garcia, Mario J., Latib, Azeem, Parwani, Purvi, and Slipczuk, Leandro

Abstract

Current guidelines of aortic stenosis (AS) management focus on valve parameters, LV systolic dysfunction, and symptoms; however, emerging data suggest that there may be benefit of aortic valve replacement before it becomes severe by present criteria. Myocardial assessment using novel multimodality imaging techniques exhibits subclinical myocardial injury and remodeling at various stages before guideline-directed interventions, which predicts adverse outcomes. This raises the question of whether implementing serial myocardial assessment should become part of the standard appraisal, thereby identifying high-risk patients aiming to minimize adverse outcomes.

Published
2024
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20. Impact of Tafamidis on Survival in a Real-World Community-Based Cohort

Author

Hussain, Kifah, primary, Macrinici, Victor, additional, Wathen, Lucas, additional, Balasubramanian, Senthil S., additional, Minga, Iva, additional, Gaznabi, Safwan, additional, Kwak, Esther, additional, Wang, Chi-Hsiung, additional, Iqbal, Suha Haider, additional, Pursnani, Amit, additional, and Sarswat, Nitasha, additional

Published
2022
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21. Continuous Remote Patient Monitoring in Patients With Heart Failure (Cascade Study): Protocol for a Mixed Methods Feasibility Study

Author

Reamer, Courtney, primary, Chi, Wei Ning, additional, Gordon, Robert, additional, Sarswat, Nitasha, additional, Gupta, Charu, additional, Gaznabi, Safwan, additional, White VanGompel, Emily, additional, Szum, Izabella, additional, Morton-Jost, Melissa, additional, Vaughn, Jorma, additional, Larimer, Karen, additional, Victorson, David, additional, Erwin, John, additional, Halasyamani, Lakshmi, additional, Solomonides, Anthony, additional, Padman, Rema, additional, and Shah, Nirav S, additional

Published
2022
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22. Bariatric Weight Loss Surgery Improves Systolic Function in Obese Patients with Heart Failure

Author

Balakumaran, Kathir, primary, Jabri, Ahmad, additional, Haddadin, Faris, additional, Hamade, Hani, additional, Lao, Nicole Mae, additional, Gaznabi, Safwan, additional, Haddadin, Suhail, additional, Garcia, Raul Angel, additional, Schwab, Tracy, additional, Shumiloff, Jennifer, additional, Kaur, Babaljeet, additional, Dhanvanthari, Sonya, additional, and Alamm, Chantal El, additional

Published
2022
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26. Continuous remote patient monitoring in heart failure patients (CASCADE study): mixed methods feasibility protocol (Preprint)

Author

Reamer, Courtney, primary, Chi, Wei Ning, additional, Gordon, Robert, additional, Sarswat, Nitasha, additional, Gupta, Charu, additional, Gaznabi, Safwan, additional, White VanGompel, Emily, additional, Szum, Isabella, additional, Morton-Jost, Melissa, additional, Vaughn, Jorma, additional, Larimer, Karen, additional, Victorson, David, additional, Erwin, John, additional, Halasyamani, Lakshmi, additional, Solomonides, Anthony, additional, Padman, Rema, additional, and Shah, Nirav S, additional

Published
2022
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31. Chronic Type A Aortic Dissection: Rare Presentation of Incidental Pericardial Effusion

Author

Abugroun, Ashraf, Subahi, Ahmed, Gaznabi, Safwan, and Daoud, Hussein

Subjects
lcsh:Diseases of the circulatory (Cardiovascular) system, medicine.medical_specialty, Case Report, 030204 cardiovascular system & hematology, Pericardial effusion, Asymptomatic, 03 medical and health sciences, Aortic aneurysm, 0302 clinical medicine, Internal medicine, Medicine, 030212 general & internal medicine, Aortic rupture, Aortic dissection, Surgical repair, business.industry, medicine.disease, Hemorrhagic pericardial effusion, Surgery, lcsh:RC666-701, cardiovascular system, Cardiology, medicine.symptom, Presentation (obstetrics), Cardiology and Cardiovascular Medicine, business
Abstract

Aortic dissection is the most devastating sequelae of aortopathy other than aortic rupture. However, aortic dissection can be asymptomatic in the acute phase with delayed symptomatic presentation or incidental diagnosis upon chest imaging. We report a case of a 63-year-old male who was diagnosed with pericardial effusion upon preoperative workup for elective cholecystectomy. Further investigations confirmed hemorrhagic pericardial effusion secondary to a chronic dissecting ascending aortic aneurysm. The patient condition was successfully managed with open surgical repair with an uneventful postoperative course. This case demonstrates an extremely rare presentation of incidental hemorrhagic pericardial effusion caused by a chronic dissecting ascending aortic aneurysm.

Published
2019

32. LVAD Vasculitis Case Series

Author

Garcia, Raul Angel, primary, Gaznabi, Safwan, additional, Musoke, Lewis, additional, Osnard, Michael, additional, Balakumaran, Kathir, additional, Armitage, Keith B., additional, Al-Kindi, Sadeer G., additional, Ginwalla, Mahazarin, additional, Abu-Omar, Yasir, additional, and Elamm, Chantal A., additional

Published
2021
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40. Successful Resolution of a Large Left Atrial and Left Atrial Appendage Thrombus with Rivaroxaban

Author

Gaznabi, Safwan, Abugroun, Ashraf, Mahbub, Hasan, and Campos, Enrique

Subjects
Article Subject, cardiovascular system, cardiovascular diseases
Abstract

A 79-year-old male was admitted to the hospital for acute exacerbation of heart failure. The patient had history of atrial fibrillation and was planned for cardioversion. Preprocedure transesophageal echocardiogram (TEE) revealed a large multilobulated mobile thrombus in the left atrial appendage. The patient refused warfarin therapy and instead chose to take rivaroxaban. Upon outpatient follow-up, 3 months later, no visible thrombus was appreciated on repeat TEE. This case demonstrates successful resolution of left atrial and left atrial appendage thrombi with the use of rivaroxaban. At present time, limited data is available to support the use of rivaroxaban for treatment of intracardiac thrombi. This case highlights the need for further studies to investigate the outcomes and relative efficiency of use of direct oral anticoagulants (DOACs) in lysis of intracardiac thrombus. The benefits of DOACs compared to the standard of therapy could increase patient compliance, reduce length of stay, and improve treatment efficacy.

Published
2019
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44. Abstract 11845: Obstructive Sleep Apnea is Not Predictive of Worse Outcomes Following Percutaneous Coronary Intervention in Acute Coronary Syndromes (ACS).

Author

Gaznabi, Safwan, Abugroun, Ashraf, and Klein, Lloyd

Subjects
*PERCUTANEOUS coronary intervention, *ACUTE coronary syndrome, *SLEEP apnea syndromes, *ADENOTONSILLECTOMY, *ACUTE kidney failure, *ADULT respiratory distress syndrome
Abstract

Introduction: Obstructive sleep apnea (OSA) is associated with adverse clinical outcomes in ACS (STEMI, NSTEMI, & unstable angina). Hypothesis: This study was undertaken to evaluate whether OSA is predictive of worse procedural outcomes, independent of comorbidities, in patients undergoing percutaneous intervention (PCI) for ACS. Methods: The National Inpatient Sample (NIS) registry from 2011-2014 was queried to identify all patients age ≥ 21 years admitted for ACS who received PCI. The primary end-point was in-hospital mortality; secondary endpoints were cardiogenic shock, stroke, respiratory failure and acute kidney injury (AKI). Multivariable logistic regression analyses were performed. Results: A total of 285,097 patients with ACS comprised the study group; of these, 17,369 (6.1%) had a diagnosis of OSA. The OSA cohort was younger (61.8+11.4 vs 63.2+13.0, p<0.001) and had more men (76% vs 67.9%, p<0.001). The non-OSA group had a higher frequency of mortality (3.0% vs 2.0%, p<0.001) and cardiogenic shock on presentation (6.3% vs 5.5%, p<0.001) but lower rate of respiratory failure (7.7% vs 10.7%, p<0.001) and AKI (9.4% vs 12.8%, p<0.001). Multivariate logistic regression analysis showed OSA was independently associated with a higher risk for respiratory failure (adjusted OR: 1.314, CI: 1.240 - 1.393 ;p<0.001), lower risk for in-hospital mortality (adjusted OR: 0.761, CI: 0.678 - 0.854; p<0.001) and peri-procedural cardiogenic shock (adjusted OR: 0.882, CI: 0.820 - 0.948; p<0.001). There was no significant difference in stroke or AKI. Conclusions: OSA patients undergoing PCI for ACS had a lower risk of mortality and peri-procedural cardiogenic shock than those without OSA. Results of this study challenge our previous expectations regarding the influence of OSA on cardiovascular disease. It is reasonable to further assess the impact of screening & managing OSA during the peri-operative PCI period. [ABSTRACT FROM AUTHOR]

Published
2018

47. Epstein-Barr Virus Infection-associated Hemophagocytic Lymphohistiocytosis.

Author

Contreras-Chavez P, Anampa-Guzmán A, Gaznabi S, and Lansigan F

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening syndrome characterized by uncontrolled immune activation. There is an aberrant activation of lym-phocytes and macrophages that results in hypercytokinemia. We aim to describe a case of secondary HLH due to primary Epstein-Barr virus (EBV) infection. A Hispanic 28-year-old man presented with sore throat and fatigue for one week. He was diagnosed with mononucleosis and discharged and was treated according to the currently available treatment. HLH is treated by diminishing the inflammation by myelosuppressive and immunosuppressive therapy. EBV infection-associated HLH is a rare disease with high mortality. It is crucial to think about it when facing a patient with fever, cytopenia, hepatosplenomegaly, and high levels of ferritin. Despite medical treatment, the patient died from multiorgan failure., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2020, Contreras-Chavez et al.)

Published
2020
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