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2,177 results on '"Gazdar, A. F."'

1. A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity

Author

Simpson, Kathryn L., Stoney, Ruth, Frese, Kristopher K., Simms, Nicole, Rowe, William, Pearce, Simon P., Humphrey, Sam, Booth, Laura, Morgan, Derrick, Dynowski, Marek, Trapani, Francesca, Catozzi, Alessia, Revill, Mitchell, Helps, Thomas, Galvin, Melanie, Girard, Luc, Nonaka, Daisuke, Carter, Louise, Krebs, Matthew G., Cook, Natalie, Carter, Mathew, Priest, Lynsey, Kerr, Alastair, Gazdar, Adi F., Blackhall, Fiona, and Dive, Caroline

Published
2020
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2. Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer

Author

Cai, Ling, Liu, Hongyu, Huang, Fang, Fujimoto, Junya, Girard, Luc, Chen, Jun, Li, Yongwen, Zhang, Yu-An, Deb, Dhruba, Stastny, Victor, Pozo, Karine, Kuo, Christin S., Jia, Gaoxiang, Yang, Chendong, Zou, Wei, Alomar, Adeeb, Huffman, Kenneth, Papari-Zareei, Mahboubeh, Yang, Lin, Drapkin, Benjamin, Akbay, Esra A., Shames, David S., Wistuba, Ignacio I., Wang, Tao, Johnson, Jane E., Xiao, Guanghua, DeBerardinis, Ralph J., Minna, John D., Xie, Yang, and Gazdar, Adi F.

Published
2021
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7. Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors

Author

Dalvi, Maithili P., Wang, Lei, Zhong, Rui, Kollipara, Rahul K., Park, Hyunsil, Bayo, Juan, Yenerall, Paul, Zhou, Yunyun, Timmons, Brenda C., Rodriguez-Canales, Jaime, Behrens, Carmen, Mino, Barbara, Villalobos, Pamela, Parra, Edwin R., Suraokar, Milind, Pataer, Apar, Swisher, Stephen G., Kalhor, Neda, Bhanu, Natarajan V., Garcia, Benjamin A., Heymach, John V., Coombes, Kevin, Xie, Yang, Girard, Luc, Gazdar, Adi F., Kittler, Ralf, Wistuba, Ignacio I., Minna, John D., and Martinez, Elisabeth D.

Published
2017
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9. Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

Author

Li, Jun, Zhao, Wei, Akbani, Rehan, Liu, Wenbin, Ju, Zhenlin, Ling, Shiyun, Vellano, Christopher P., Roebuck, Paul, Yu, Qinghua, Eterovic, A. Karina, Byers, Lauren A., Davies, Michael A., Deng, Wanleng, Gopal, Y.N. Vashisht, Chen, Guo, von Euw, Erika M., Slamon, Dennis, Conklin, Dylan, Heymach, John V., Gazdar, Adi F., Minna, John D., Myers, Jeffrey N., Lu, Yiling, Mills, Gordon B., and Liang, Han

Published
2017
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10. MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition

Author

Mollaoglu, Gurkan, Guthrie, Matthew R., Böhm, Stefanie, Brägelmann, Johannes, Can, Ismail, Ballieu, Paul M., Marx, Annika, George, Julie, Heinen, Christine, Chalishazar, Milind D., Cheng, Haixia, Ireland, Abbie S., Denning, Kendall E., Mukhopadhyay, Anandaroop, Vahrenkamp, Jeffery M., Berrett, Kristofer C., Mosbruger, Timothy L., Wang, Jun, Kohan, Jessica L., Salama, Mohamed E., Witt, Benjamin L., Peifer, Martin, Thomas, Roman K., Gertz, Jason, Johnson, Jane E., Gazdar, Adi F., Wechsler-Reya, Robert J., Sos, Martin L., and Oliver, Trudy G.

Published
2017
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11. Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development.

Author

O'Shaughnessy, Joyce A, Kelloff, Gary J, Gordon, Gary B, Dannenberg, Andrew J, Hong, Waun Ki, Fabian, Carol J, Sigman, Caroline C, Bertagnolli, Monica M, Stratton, Steven P, Lam, Stephen, Nelson, William G, Meyskens, Frank L, Alberts, David S, Follen, Michele, Rustgi, Anil K, Papadimitrakopoulou, Vali, Scardino, Peter T, Gazdar, Adi F, Wattenberg, Lee W, Sporn, Michael B, Sakr, Wael A, Lippman, Scott M, and Von Hoff, Daniel D

Subjects
Humans, Neoplasms, Carcinoma in Situ, Cervical Intraepithelial Neoplasia, Prostatic Intraepithelial Neoplasia, Colorectal Neoplasms, Mouth Neoplasms, Barrett Esophagus, Cardiovascular Diseases, Keratosis, Antineoplastic Agents, Time Factors, Female, Male, Urinary Bladder Neoplasms, Clinical Trials as Topic, Oncology & Carcinogenesis, Oncology and Carcinogenesis
Abstract

Precancer or intraepithelial neoplasia (IEN) is a noninvasive lesion that has genetic abnormalities, loss of cellular control functions, and some phenotypic characteristics of invasive cancer and that predicts for a substantial likelihood of developing invasive cancer. The AACR Task Force on the Treatment and Prevention of IEN has delineated the relationship between IEN and cancer risk as well as the clinical benefit that can be derived from reducing IEN burden. Although several effective endoscopic and surgical treatments for IEN have become standard medical practice, these interventions can confer morbidity and do not treat the entire epithelial field at risk. The incidence of many epithelial cancers is continuing to rise, the number of individuals at risk is increasing with the aging population, and the rapid advancement of imaging and molecular diagnostics is bringing to light precancers that were heretofore clinically silent. There is therefore an urgent need to rapidly develop new treatment and prevention agents for IEN. The AACR IEN Task Force recommends focusing on established precancers as the target for new agent development because of the close association between dysplasia and invasive cancer and because a convincing reduction in IEN burden provides patient benefit by reducing cancer risk and/or by decreasing the need for invasive interventions. The IEN Task Force proposes several clinical trial designs that provide practical and feasible approaches to the rapid development of new agents to treat and prevent precancer.

Published
2002

15. Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

Author

Bunn, Paul A., Jr., Minna, John D., Augustyn, Alexander, Gazdar, Adi F., Ouadah, Youcef, Krasnow, Mark A., Berns, Anton, Brambilla, Elisabeth, Rekhtman, Natasha, Massion, Pierre P., Niederst, Matthew, Peifer, Martin, Yokota, Jun, Govindan, Ramaswamy, Poirier, John T., Byers, Lauren A., Wynes, Murry W., McFadden, David G., MacPherson, David, Hann, Christine L., Farago, Anna F., Dive, Caroline, Teicher, Beverly A., Peacock, Craig D., Johnson, Jane E., Cobb, Melanie H., Wendel, Hans-Guido, Spigel, David, Sage, Julien, Yang, Ping, Pietanza, M. Catherine, Krug, Lee M., Heymach, John, Ujhazy, Peter, Zhou, Caicun, Goto, Koichi, Dowlati, Afshin, Christensen, Camilla Laulund, Park, Keunchil, Einhorn, Lawrence H., Edelman, Martin J., Giaccone, Giuseppe, Gerber, David E., Salgia, Ravi, Owonikoko, Taofeek, Malik, Shakun, Karachaliou, Niki, Gandara, David R., Slotman, Ben J., Blackhall, Fiona, Goss, Glenwood, Thomas, Roman, Rudin, Charles M., and Hirsch, Fred R.

Published
2016
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21. Supplementary Figures 1-4 from Knockdown of Oncogenic KRAS in Non–Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy

Author

Sunaga, Noriaki, primary, Shames, David S., primary, Girard, Luc, primary, Peyton, Michael, primary, Larsen, Jill E., primary, Imai, Hisao, primary, Soh, Junichi, primary, Sato, Mitsuo, primary, Yanagitani, Noriko, primary, Kaira, Kyoichi, primary, Xie, Yang, primary, Gazdar, Adi F., primary, Mori, Masatomo, primary, and Minna, John D., primary

Published
2023
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22. Data from Knockdown of Oncogenic KRAS in Non–Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy

Author

Sunaga, Noriaki, primary, Shames, David S., primary, Girard, Luc, primary, Peyton, Michael, primary, Larsen, Jill E., primary, Imai, Hisao, primary, Soh, Junichi, primary, Sato, Mitsuo, primary, Yanagitani, Noriko, primary, Kaira, Kyoichi, primary, Xie, Yang, primary, Gazdar, Adi F., primary, Mori, Masatomo, primary, and Minna, John D., primary

Published
2023
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23. Supplementary Tables 1-2 from Knockdown of Oncogenic KRAS in Non–Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy

Author

Sunaga, Noriaki, primary, Shames, David S., primary, Girard, Luc, primary, Peyton, Michael, primary, Larsen, Jill E., primary, Imai, Hisao, primary, Soh, Junichi, primary, Sato, Mitsuo, primary, Yanagitani, Noriko, primary, Kaira, Kyoichi, primary, Xie, Yang, primary, Gazdar, Adi F., primary, Mori, Masatomo, primary, and Minna, John D., primary

Published
2023
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25. Supplementary Table 3 from Knockdown of Oncogenic KRAS in Non–Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy

Author

Sunaga, Noriaki, primary, Shames, David S., primary, Girard, Luc, primary, Peyton, Michael, primary, Larsen, Jill E., primary, Imai, Hisao, primary, Soh, Junichi, primary, Sato, Mitsuo, primary, Yanagitani, Noriko, primary, Kaira, Kyoichi, primary, Xie, Yang, primary, Gazdar, Adi F., primary, Mori, Masatomo, primary, and Minna, John D., primary

Published
2023
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26. Data from Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations

Author

Sato, Mitsuo, primary, Larsen, Jill E., primary, Lee, Woochang, primary, Sun, Han, primary, Shames, David S., primary, Dalvi, Maithili P., primary, Ramirez, Ruben D., primary, Tang, Hao, primary, DiMaio, John Michael, primary, Gao, Boning, primary, Xie, Yang, primary, Wistuba, Ignacio I., primary, Gazdar, Adi F., primary, Shay, Jerry W., primary, and Minna, John D., primary

Published
2023
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27. Supplementary Methods, Tables 1 - 4, Figures 1 - 7 from Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations

Author

Sato, Mitsuo, primary, Larsen, Jill E., primary, Lee, Woochang, primary, Sun, Han, primary, Shames, David S., primary, Dalvi, Maithili P., primary, Ramirez, Ruben D., primary, Tang, Hao, primary, DiMaio, John Michael, primary, Gao, Boning, primary, Xie, Yang, primary, Wistuba, Ignacio I., primary, Gazdar, Adi F., primary, Shay, Jerry W., primary, and Minna, John D., primary

Published
2023
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29. Supplementary Methods from Knockdown of Oncogenic KRAS in Non–Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy

Author

Sunaga, Noriaki, primary, Shames, David S., primary, Girard, Luc, primary, Peyton, Michael, primary, Larsen, Jill E., primary, Imai, Hisao, primary, Soh, Junichi, primary, Sato, Mitsuo, primary, Yanagitani, Noriko, primary, Kaira, Kyoichi, primary, Xie, Yang, primary, Gazdar, Adi F., primary, Mori, Masatomo, primary, and Minna, John D., primary

Published
2023
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30. Supplementary Figure Legends 1-4 from Knockdown of Oncogenic KRAS in Non–Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy

Author

Sunaga, Noriaki, primary, Shames, David S., primary, Girard, Luc, primary, Peyton, Michael, primary, Larsen, Jill E., primary, Imai, Hisao, primary, Soh, Junichi, primary, Sato, Mitsuo, primary, Yanagitani, Noriko, primary, Kaira, Kyoichi, primary, Xie, Yang, primary, Gazdar, Adi F., primary, Mori, Masatomo, primary, and Minna, John D., primary

Published
2023
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33. Supplementary Material from An Expression Signature as an Aid to the Histologic Classification of Non–Small Cell Lung Cancer

Author

Girard, Luc, primary, Rodriguez-Canales, Jaime, primary, Behrens, Carmen, primary, Thompson, Debrah M., primary, Botros, Ihab W., primary, Tang, Hao, primary, Xie, Yang, primary, Rekhtman, Natasha, primary, Travis, William D., primary, Wistuba, Ignacio I., primary, Minna, John D., primary, and Gazdar, Adi F., primary

Published
2023
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35. Data from Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis

Author

Tang, Ximing, primary, Kadara, Humam, primary, Behrens, Carmen, primary, Liu, Diane D, primary, Xiao, Yun, primary, Rice, David, primary, Gazdar, Adi F., primary, Fujimoto, Junya, primary, Moran, Cesar, primary, Varella-Garcia, Marileila, primary, Lee, J Jack, primary, Hong, Waun Ki, primary, and Wistuba, Ignacio I., primary

Published
2023
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36. Supplementary Methods, Figures 1 - 7, and Tables 1 - 6 from Radiation-Enhanced Lung Cancer Progression in a Transgenic Mouse Model of Lung Cancer Is Predictive of Outcomes in Human Lung and Breast Cancer

Author

Delgado, Oliver, primary, Batten, Kimberly G., primary, Richardson, James A., primary, Xie, Xian-Jin, primary, Gazdar, Adi F., primary, Kaisani, Aadil A., primary, Girard, Luc, primary, Behrens, Carmen, primary, Suraokar, Milind, primary, Fasciani, Gail, primary, Wright, Woodring E., primary, Story, Michael D., primary, Wistuba, Ignacio I., primary, Minna, John D., primary, and Shay, Jerry W., primary

Published
2023
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40. Supplementary Data from Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis

Author

Tang, Ximing, primary, Kadara, Humam, primary, Behrens, Carmen, primary, Liu, Diane D, primary, Xiao, Yun, primary, Rice, David, primary, Gazdar, Adi F., primary, Fujimoto, Junya, primary, Moran, Cesar, primary, Varella-Garcia, Marileila, primary, Lee, J Jack, primary, Hong, Waun Ki, primary, and Wistuba, Ignacio I., primary

Published
2023
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41. Supplementary Figure 4 from Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells

Author

Shien, Kazuhiko, primary, Toyooka, Shinichi, primary, Yamamoto, Hiromasa, primary, Soh, Junichi, primary, Jida, Masaru, primary, Thu, Kelsie L., primary, Hashida, Shinsuke, primary, Maki, Yuho, primary, Ichihara, Eiki, primary, Asano, Hiroaki, primary, Tsukuda, Kazunori, primary, Takigawa, Nagio, primary, Kiura, Katsuyuki, primary, Gazdar, Adi F., primary, Lam, Wan L., primary, and Miyoshi, Shinichiro, primary

Published
2023
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42. Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets

Author

Taguchi, Ayumu, primary, Taylor, Allen D., primary, Rodriguez, Jaime, primary, Çeliktaş, Müge, primary, Liu, Hui, primary, Ma, Xiaotu, primary, Zhang, Qing, primary, Wong, Chee-Hong, primary, Chin, Alice, primary, Girard, Luc, primary, Behrens, Carmen, primary, Lam, Wan L., primary, Lam, Stephen, primary, Minna, John D., primary, Wistuba, Ignacio I., primary, Gazdar, Adi F., primary, and Hanash, Samir M., primary

Published
2023
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43. Data from PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

Author

Yamamoto, Hiromasa, primary, Shigematsu, Hisayuki, primary, Nomura, Masaharu, primary, Lockwood, William W., primary, Sato, Mitsuo, primary, Okumura, Naoki, primary, Soh, Junichi, primary, Suzuki, Makoto, primary, Wistuba, Ignacio I., primary, Fong, Kwun M., primary, Lee, Huei, primary, Toyooka, Shinichi, primary, Date, Hiroshi, primary, Lam, Wan L., primary, Minna, John D., primary, and Gazdar, Adi F., primary

Published
2023
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44. Supplementary Table S2 from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival

Author

Schliekelman, Mark J., primary, Taguchi, Ayumu, primary, Zhu, Jun, primary, Dai, Xudong, primary, Rodriguez, Jaime, primary, Celiktas, Muge, primary, Zhang, Qing, primary, Chin, Alice, primary, Wong, Chee-Hong, primary, Wang, Hong, primary, McFerrin, Lisa, primary, Selamat, Suhaida A., primary, Yang, Chenchen, primary, Kroh, Evan M., primary, Garg, Kavita S., primary, Behrens, Carmen, primary, Gazdar, Adi F., primary, Laird-Offringa, Ite A., primary, Tewari, Muneesh, primary, Wistuba, Ignacio I., primary, Thiery, Jean P., primary, and Hanash, Samir M., primary

Published
2023
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45. Data from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets

Author

Taguchi, Ayumu, primary, Taylor, Allen D., primary, Rodriguez, Jaime, primary, Çeliktaş, Müge, primary, Liu, Hui, primary, Ma, Xiaotu, primary, Zhang, Qing, primary, Wong, Chee-Hong, primary, Chin, Alice, primary, Girard, Luc, primary, Behrens, Carmen, primary, Lam, Wan L., primary, Lam, Stephen, primary, Minna, John D., primary, Wistuba, Ignacio I., primary, Gazdar, Adi F., primary, and Hanash, Samir M., primary

Published
2023
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47. Supplementary Table 2 from Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells

Author

Shien, Kazuhiko, primary, Toyooka, Shinichi, primary, Yamamoto, Hiromasa, primary, Soh, Junichi, primary, Jida, Masaru, primary, Thu, Kelsie L., primary, Hashida, Shinsuke, primary, Maki, Yuho, primary, Ichihara, Eiki, primary, Asano, Hiroaki, primary, Tsukuda, Kazunori, primary, Takigawa, Nagio, primary, Kiura, Katsuyuki, primary, Gazdar, Adi F., primary, Lam, Wan L., primary, and Miyoshi, Shinichiro, primary

Published
2023
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48. Supplementary Figure 2 from Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells

Author

Shien, Kazuhiko, primary, Toyooka, Shinichi, primary, Yamamoto, Hiromasa, primary, Soh, Junichi, primary, Jida, Masaru, primary, Thu, Kelsie L., primary, Hashida, Shinsuke, primary, Maki, Yuho, primary, Ichihara, Eiki, primary, Asano, Hiroaki, primary, Tsukuda, Kazunori, primary, Takigawa, Nagio, primary, Kiura, Katsuyuki, primary, Gazdar, Adi F., primary, Lam, Wan L., primary, and Miyoshi, Shinichiro, primary

Published
2023
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50. Supplementary Figure 1 from PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

Author

Yamamoto, Hiromasa, primary, Shigematsu, Hisayuki, primary, Nomura, Masaharu, primary, Lockwood, William W., primary, Sato, Mitsuo, primary, Okumura, Naoki, primary, Soh, Junichi, primary, Suzuki, Makoto, primary, Wistuba, Ignacio I., primary, Fong, Kwun M., primary, Lee, Huei, primary, Toyooka, Shinichi, primary, Date, Hiroshi, primary, Lam, Wan L., primary, Minna, John D., primary, and Gazdar, Adi F., primary

Published
2023
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