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1. Intrinsic Finite Element Error Analysis on Manifolds with Regge Metrics, with Applications to Calculating Connection Forms

Author: Gawlik, Evan S. and McKee, Jack
Subjects: Mathematics - Numerical Analysis, Mathematics - Differential Geometry
Abstract: We present some aspects of the theory of finite element exterior calculus as applied to partial differential equations on manifolds, especially manifolds endowed with an approximate metric called a Regge metric. Our treatment is intrinsic, avoiding wherever possible the use of preferred coordinates or a preferred embedding into an ambient space, which presents some challenges but also conceptual and possibly computational advantages. As an application, we analyze and implement a method for computing an approximate Levi-Civita connection form for a disc whose metric is itself approximate., Comment: 32 pages, 2 figures
Published: 2024

2. Localization of macroscopic sources of magnetic field using optical fibers doped with NV-rich sub-micron diamonds and zero-field resonance

Author: Mrózek, Mariusz, Filipkowski, Adam, Gawlik, Wojciech, Buczyński, Ryszard, Wojciechowski, Adam M., and Klimczak, Mariusz
Subjects: Physics - Applied Physics
Abstract: We employ an optical fiber doped with randomly oriented fluorescent sub-micron diamonds and the novel zero-field resonance protocol to collect information on the localization and orientation of a magnetic-field source and its distribution. Many previous demonstrations of diamond-based magnetic field sensing achieved ultrahigh sensitivities down to the fT range warranted by manipulating spin states of the diamond nitrogen vacancy (NV) centers with externally applied radio or microwaves. The application of such oscillating fields is problematic in distributed magnetic-field measurements and may be incompatible with specific targets. Instead of relying on these approaches, we leveraged cross-relaxations of particular spin-state populations of the NV center under a magnetic field, thus observing zero-field resonances and making external radio frequency fields redundant. Combined with an optical fiber sensitive to the magnetic field along its entire length, remote sensing was realized that returned information on the spatial field distribution without using any moving mechanical elements in the detection system. Variation of the spatial parameters of the investigated field was achieved simply by controlling the current in a pair of induction coils easily integrable with optical fibers without limiting the fiber-specific functionality of the optical readout taking place at a fixed location at the optical fiber output. Lifting of the requirements related to the mechanical scanning of the fiber, the application of external fields, and the orientation of the NV centers against the measured field mark a very practical step forward in optically driven magnetic field sensing, not easily achievable with earlier implementations., Comment: 7 pages, 3 figures
Published: 2024

3. Microwave-free imaging magnetometry with nitrogen-vacancy centers in nanodiamonds at near-zero field

Author: Sengottuvel, Saravanan, Dhungel, Omkar, Mrózek, Mariusz, Wickenbrock, Arne, Budker, Dmitry, Gawlik, Wojciech, and Wojciechowski, Adam M.
Subjects: Quantum Physics
Abstract: Magnetometry using Nitrogen-Vacancy (NV) color centers in diamond predominantly relies on microwave spectroscopy. However, microwaves may hinder certain studies involving biological systems or thin conductive samples. This work demonstrates a wide-field, microwave-free imaging magnetometer utilizing NV centers in nanodiamonds by exploiting the cross-relaxation feature near zero magnetic fields under ambient conditions without applying microwaves. For this purpose, we measure the center shift, contrast, and linewidth of the zero-field cross-relaxation in 140 nm nanodiamonds drop-cast on a current-carrying conductive pattern while scanning a background magnetic field, achieving a sensitivity of 4.5 $\mathrm{\mu T/\sqrt{Hz}}$. Our work allows for applying the NV zero-field feature in nanodiamonds for magnetic field sensing in the zero and low-field regimes and highlights the potential for microwave-free all-optical wide-field magnetometry based on nanodiamonds., Comment: 8 pages, 5 figures
Published: 2024

4. Measurement and analysis of the $^{246}$Cm and $^{248}$Cm neutron capture cross-sections at the EAR2 of the n TOF facility

Author: Alcayne, V., Kimura, A., Mendoza, E., Cano-Ott, D., Aberle, O., Álvarez-Velarde, F., Amaducci, S., Andrzejewski, J., Audouin, L., Bécares, V., Babiano-Suarez, V., Bacak, M., Barbagallo, M., Bečvář, F., Bellia, G., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Busso, M., Caamaño, M., Caballero-Ontanaya, L., Calviño, F., Calviani, M., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Damone, L. A., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fernández-Domınguez, B., Ferrari, A., Finocchiaro, P., Furman, V., Göbel, K., Garg, R., Gawlik-Ramiega, A., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Guerrero, C., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Kivel, N., Kokkoris, M., Kopatch, Y., Krtička, M., Kurtulgil, D., Ladarescu, I., Lederer-Woods, C., Leeb, H., Lerendegui-Marco, J., Meo, S. Lo, Lonsdale, S. J., Macina, D., Manna, A., Martınez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Matteucci, F., Maugeri, E. A., Mazzone, A., Mengoni, A., Michalopoulou, V., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Ogállar, F., Oprea, A., Patronis, N., Pavlik, A., de Rada, A. Pérez, Perkowski, J., Persanti, L., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Ramos-Doval, D., Rauscher, T., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Tagliente, G., Tain, J. L., Talip, T., Tarifeño-Saldivia, A., Tassan-Got, L., Torres-Sánchez, P., Tsinganis, A., Ulrich, J., Urlass, S., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T., and Žugec, P.
Subjects: Nuclear Experiment
Abstract: The $^{246}$Cm(n,$\gamma$) and $^{248}$Cm(n,$\gamma$) cross-sections have been measured at the Experimental Area 2 (EAR2) of the n_TOF facility at CERN with three C$_6$D$_6$ detectors. This measurement is part of a collective effort to improve the capture cross-section data for Minor Actinides (MAs), which are required to estimate the production and transmutation rates of these isotopes in light water reactors and innovative reactor systems. In particular, the neutron capture in $^{246}$Cm and $^{248}$Cm open the path for the formation of other Cm isotopes and heavier elements such as Bk and Cf and the knowledge of (n,$\gamma$) cross-sections of these Cm isotopes plays an important role in the transport, transmutation and storage of the spent nuclear fuel. The reactions $^{246}$Cm(n,$\gamma$) and $^{248}$Cm(n,$\gamma$) have been the two first capture measurements analyzed at n_TOF EAR2. Until this experiment and two recent measurements performed at J-PARC, there was only one set of data of the capture cross-sections of $^{246}$Cm and $^{248}$Cm, that was obtained in 1969 in an underground nuclear explosion experiment. In the measurement at n_TOF a total of 13 resonances of $^{246}$Cm between 4 and 400 eV and 5 of $^{248}$Cm between 7 and 100 eV have been identified and fitted. The radiative kernels obtained for $^{246}$Cm are compatible with JENDL-5, but some of them are not with JENDL-4, which has been adopted by JEFF-3.3 and ENDF/B-VIII.0. The radiative kernels obtained for the first three $^{248}$Cm resonances are compatible with JENDL-5, however, the other two are not compatible with any other evaluation and are 20% and 60% larger than JENDL-5.
Published: 2024

5. Results of the 244Cm, 246Cm and 248Cm neutron-induced capture cross sections measurements at EAR1 and EAR2 of the n_TOF facility

Author: Alcayne V., Mendoza E., Cano-Ott D., Kimura A., Aberle O., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V., Bacak M., Barbagallo M., Bécares V., Bečvář F., Bellia G., Berthoumieux E., Billowes J., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Diakaki M., Dietz M., Domingo-Pardo C., Dressler R., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Glodariu T., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Kadi Y., Käppeler F., Kivel N., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C., Lerendegui-Marco J., Lo Meo S., Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P. F., Mastromarco M., Matteucci F., Maugeri E., Mazzone A., Mengoni A., Michalopoulou V., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Piersanti L., Porras I., Praena J., Quesada J. M., Radeck D., Ramos Doval D., Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Smith A. G., Sosnin N., Stamatopoulos A., Tagliente G., Tain J. L., Talip Z., Tarifeño-Saldivia A. E., Tassan-Got L., Torres-Sánchez P., Tsinganis A., Ulrich J., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: Accurate neutron capture cross section data for minor actinides (MAs) are required to estimate the production and transmutation rates of MAs in light water reactors, critical fast reactors like Gen-IV systems, and other innovative reactor systems such as accelerator driven systems (ADS). In particular, 244Cm, 246Cm and 248Cm play a role in the transport, storage and transmutation of the nuclear waste of the current nuclear reactors, due to the contribution of these isotopes to the radiotoxicity, neutron emission, and decay heat in the spent nuclear fuel. Also, capture reactions in these Cm isotopes open the path for the formation of heavier elements. In this work, the results of the capture cross section measurement on 244Cm, 246Cm and 248Cm performed at the CERN n_TOF facility are presented. It is important to notice that the Cm samples used in the experiment at n_TOF have been used previously in an experiment at J-PARC, this experiment and the previous one done in the 70s with a nuclear explosion were the only previous capture experiments for these isotopes. At n_TOF, the capture cross section measurements of 244Cm, 246Cm and 248Cm were performed at the 20 m vertical flight path (EAR2) with three C6D6 total energy detectors. In addition, the cross section of 244Cm was measured at the 185 m flight path (EAR1) with a Total Absorption Calorimeter (TAC). The combination of measurements in EAR1 and EAR2 has contributed to controlling and reducing the systematic uncertainties in the results. The compatibility of the different measurements performed and the techniques to obtain the results are presented in this paper as well as the procedure to obtain the resonance parameters.
Published: 2023
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6. Optically detected magnetic resonance study of thermal effects due to absorbing environment around nitrogen-vacancy-nanodiamond powders

Author: Jani, Mona, Orzechowska, Zuzanna, Mrozek, Mariusz, Mitura-Nowak, Marzena, Gawlik, Wojciech, and Wojciechowski, Adam M.
Subjects: Condensed Matter - Materials Science, Quantum Physics
Abstract: We implanted Fe$^+$ ions in nanodiamond (ND) powder containing negatively charged nitrogen-vacancy (NV-) centers and studied their Raman spectra and optically detected magnetic resonance (ODMR) in various applied magnetic fields with green light (532 nm) excitation. In Raman spectra, we observed a blue shift of the NV$^-$ peak associated with the conversion of the electronic sp$^3$ configuration to the disordered sp$^2$ one typical for the carbon/graphite structure. In the ODMR spectra, we observed a red shift of the resonance position caused by local heating by an absorptive environment that recovers after annealing. To reveal the red shift mechanism in ODMR, we created a controlled absorptive environment around ND by adding iron-based Fe$_2$O$_3$ and graphitic sp$^2$ powders to the ND suspension. This admixture caused a substantial increase in the observed shift proportional to the applied laser power, corresponding to an increase in the local temperature by 150-180 K. This surprisingly large shift is absent in non-irradiated NV-ND powders, is associated only with the modification of the local temperature by the absorptive environment of NV-NDs and can be studied using ODMR signals of NV$^-$., Comment: 21 pages, 6 figures
Published: 2024

7. Study on ploughing phenomena in tool flank face workpiece interface including tool wear effect during ball end milling

Author: Wojciechowski, S., Spiewak, J. Krajewska, Maruda, R. W., Krolczyk, G. M., Nieslony, P., Wieczorowski, M., and Gawlik, J.
Subjects: Physics - Applied Physics
Abstract: Ploughing phenomena occurring during precise machining processes affect the formation of surface finish and progress of tool wear. Therefore, this study presents an evaluation of ploughing phenomenon by studying the ploughing forces in tool flank face workpiece interface during precise ball end milling of AISI L6 alloy steel. Developed original model of ploughing forces involved the effect of minimum uncut chip thickness hmin and ploughing volume during ball-end milling. Estimated ploughing forces are sensitive to variations of surface inclinations and progressing tool wear. Moreover, intense growth of ploughing force during milling with worn tool is affected by irregular and non-circular profile of worn cutting edge below the stagnant point, and by the appearance of attrition and micro-grooves on tool flank face., Comment: 31 pages, 23 figures
Published: 2024

8. Multimodal Analysis of Traction Forces and Temperature Dynamics of Living Cells with Diamond-Embedded Substrate

Author: Kołodziej, Tomasz, Mrózek, Mariusz, Sengottuvel, Saravanan, Głowacki, Maciej J., Ficek, Mateusz, Gawlik, Wojciech, Rajfur, Zenon, and Wojciechowski, Adam
Subjects: Physics - Biological Physics
Abstract: Cells and tissues are constantly exposed to various chemical and physical signals that intricately regulate various physiological and pathological processes. This study explores the integration of two biophysical methods, Traction Force Microscopy (TFM) and Optically-Detected Magnetic Resonance (ODMR), to concurrently assess cellular traction forces and local relative temperature. We present a novel elastic substrate with embedded nitrogen-vacancy microdiamonds, that facilitate ODMR-TFM measurements. Optimization efforts have focused on minimizing the sample illumination and experiment duration to mitigate biological perturbations. Our hybrid ODMR-TFM technique yields precise TFM maps and achieves approximately 1K accuracy in relative temperature measurements. Notably, our setup, employing a simple wide-field fluorescence microscope with standard components, demonstrates the broader feasibility of these techniques in life-science laboratories. By elucidating the physical aspects of cellular behavior beyond the existing methods, this approach opens avenues for a deeper understanding and may inspire diverse biomedical applications., Comment: 19 pages, 5 figures
Published: 2024
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9. Blow-up Whitney forms, shadow forms, and Poisson processes

Author: Berchenko-Kogan, Yakov and Gawlik, Evan S.
Subjects: Mathematics - Numerical Analysis, Mathematics - Differential Geometry, 65N30, 58A10
Abstract: The Whitney forms on a simplex $T$ admit high-order generalizations that have received a great deal of attention in numerical analysis. Less well-known are the shadow forms of Brasselet, Goresky, and MacPherson. These forms generalize the Whitney forms, but have rational coefficients, allowing singularities near the faces of $T$. Motivated by numerical problems that exhibit these kinds of singularities, we introduce degrees of freedom for the shadow $k$-forms that are well-suited for finite element implementations. In particular, we show that the degrees of freedom for the shadow forms are given by integration over the $k$-dimensional faces of the blow-up $\tilde T$ of the simplex $T$. Consequently, we obtain an isomorphism between the cohomology of the complex of shadow forms and the cellular cohomology of $\tilde T$, which vanishes except in degree zero. Additionally, we discover a surprising probabilistic interpretation of shadow forms in terms of Poisson processes. This perspective simplifies several proofs and gives a way of computing bases for the shadow forms using a straightforward combinatorial calculation., Comment: 46 pages, 8 figures, 3 tables
Published: 2024

10. Near-zero-field microwave-free magnetometry with nitrogen-vacancy centers in nanodiamonds

Author: Dhungel, Omkar, Mrózek, Mariusz, Lenz, Till, Ivády, Viktor, Gali, Adam, Wickenbrock, Arne, Budker, Dmitry, Gawlik, Wojciech, and Wojciechowski, Adam M.
Subjects: Condensed Matter - Mesoscale and Nanoscale Physics, Physics - Atomic Physics
Abstract: We study the fluorescence of nanodiamond ensembles as a function of static external magnetic field and observe characteristic dip features close to the zero field with potential for magnetometry applications. We analyze the dependence of the features width and contrast of the feature on the size of the diamond (in the range 30 nm to 3 um) and on the strength of a bias magnetic field applied transversely to the field being scanned. We also perform optically detected magnetic resonance (ODMR) measurements to quantify the strain splitting of the zero-field ODMR resonance across various nanodiamond sizes and compare it with the width and contrast measurements of the zero-field fluorescence features for both nanodiamonds and bulk samples. The observed properties provide compelling evidence of cross-relaxation effects in the NV system occurring close to zero magnetic fields. Finally, the potential of this technique for use in practical magnetometry is discussed., Comment: 9 pages, 5 figures
Published: 2024
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11. Symptoms and preoperative goals in patients with pelvic organ prolapse

Author: Joanna K. Trawińska, Andrzej Skręt, Bożena Konkol, Bogusław Gawlik, Joanna Bielatowicz, Małgorzata Gawlik, Sebastian Kowalski, Edyta M. Barnaś, and Joanna Skręt-Magierło
Subjects: pelvic organ prolapse, symptoms, preoperative goals, Nursing, RT1-120
Published: 2024
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12. Tracking the Spread of the BA.2.86 Lineage in Italy Through Wastewater Analysis

Author: Veneri, C., Brandtner, D., Mancini, P., Bonanno Ferraro, G., Iaconelli, M., Suffredini, E., Petrillo, M., Leoni, G., Paracchini, V., Gawlik, B. M., Marchini, A., and La Rosa, G.
Published: 2024
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13. Vaccination status of patients with primary immunodeficiencies in Germany—a multicentric epidemiologic analysis

Author: Schwaneck, Eva C., Harasim, Anna S., Tony, Hans-Peter, Gawlik, Micha, Witte, Torsten, Joos, Stefanie, Gernert, Michael, Schmalzing, Marc, Morbach, Henner, Fröhlich, Matthias, and Krone, Manuel
Published: 2024
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14. Fabrication of luminescent disc-shaped microstructures via wet-chemical etching of hybrid sol–gel layers for potential photonic applications

Author: Duda, Łukasz, Rola, Krzysztof, Łukomski, Michał, Gawlik, Andrzej, Olszewski, Jacek, Czajkowski, Maciej, Cybińska, Joanna, and Guzik, Małgorzata
Published: 2024
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15. How Are You Feeling Today? Dynamic and Static Indices of Daily Affect Predict Psychological Adjustment One Year Later in a Multi-cohort, Longitudinal Investigation

Author: Mitchell, Benjamin J., Baugher, Brittany, Gawlik, Emily, Richmond, Julia, Sidney, Pooja G., Taber, Jennifer M., Thompson, Clarissa A., and Coifman, Karin G.
Published: 2024
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16. Sustainable wastewater reuse for agriculture

Author: Christou, Anastasis, Beretsou, Vasiliki G., Iakovides, Iakovos C., Karaolia, Popi, Michael, Costas, Benmarhnia, Tarik, Chefetz, Benny, Donner, Erica, Gawlik, Bernd Manfred, Lee, Yunho, Lim, Teik Thye, Lundy, Lian, Maffettone, Roberta, Rizzo, Luigi, Topp, Edward, and Fatta-Kassinos, Despo
Published: 2024
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17. Pushing the high count rate limits of scintillation detectors for challenging neutron-capture experiments

Author: Correa, J. Balibrea, Lerendegui-Marco, J., Babiano-Suarez, V., Domingo-Pardo, C., Ladarescu, I., Tarifeño-Saldivia, A., Alcayne, V., Cano-Ott, D., González-Romero, E., Martínez, T., Mendoza, E., de Rada, A. Pérez, del Olmo, J. Plaza, Sánchez-Caballero, A., Casanovas, A., Calviño, F., Valenta, S., Aberle, O., Altieri, S., Amaducci, S., Andrzejewski, J., Bacak, M., Beltrami, C., Bennett, S., Bernardes, A. P., Berthoumieux, E., Beyer, R., Boromiza, M., Bosnar, D., Caamaño, M., Calviani, M., Castelluccio, D. M., Cerutti, F., Cescutti, G., Chasapoglou, S., Chiaveri, E., Colombetti, P., Colonna, N., Camprini, P. Console, Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Dellmann, S., Di Castro, M., Di Maria, S., Diakaki, M., Dietz, M., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fargier, S., Fernández, B., Fernández-Domínguez, B., Finocchiaro, P., Fiore, S., Furman, V., García-Infantes, F., Gawlik-Ramikega, A., Gervino, G., Gilardoni, S., Guerrero, C., Gunsing, F., Gustavino, C., Heyse, J., Hillman, W., Jenkins, D. G., Jericha, E., Junghans, A., Kadi, Y., Kaperoni, K., Kaur, G., Kimura, A., Knapová, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kyritsis, N., Lederer-Woods, C., Lerner, G., Manna, A., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E. A., Mazzone, A., Mengoni, A., Michalopoulou, V., Milazzo, P. M., Mucciola, R., Murtas, F., Musacchio-Gonzalez, E., Musumarra, A., Negret, A., Pérez-Maroto, P., Patronis, N., Pavón-Rodríguez, J. A., Pellegriti, M. G., Perkowski, J., Petrone, C., Pirovano, E., Pomp, S., Porras, I., Praena, J., Quesada, J. M., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sabaté-Gilarte, M., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A. G., Sosnin, N. V., Stamati, M. E., Sturniolo, A., Tagliente, G., Tarrío, D., Torres-Sánchez, P., Vagena, E., Variale, V., Vaz, P., Vecchio, G., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T., Zarrella, R., and Žugec, P.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: One of the critical aspects for the accurate determination of neutron capture cross sections when combining time-of-flight and total energy detector techniques is the characterization and control of systematic uncertainties associated to the measuring devices. In this work we explore the most conspicuous effects associated to harsh count rate conditions: dead-time and pile-up effects. Both effects, when not properly treated, can lead to large systematic uncertainties and bias in the determination of neutron cross sections. In the majority of neutron capture measurements carried out at the CERN n\_TOF facility, the detectors of choice are the C$_{6}$D$_{6}$ liquid-based either in form of large-volume cells or recently commissioned sTED detector array, consisting of much smaller-volume modules. To account for the aforementioned effects, we introduce a Monte Carlo model for these detectors mimicking harsh count rate conditions similar to those happening at the CERN n\_TOF 20~m fligth path vertical measuring station. The model parameters are extracted by comparison with the experimental data taken at the same facility during 2022 experimental campaign. We propose a novel methodology to consider both, dead-time and pile-up effects simultaneously for these fast detectors and check the applicability to experimental data from $^{197}$Au($n$,$\gamma$), including the saturated 4.9~eV resonance which is an important component of normalization for neutron cross section measurements.
Published: 2023

18. Finite element approximation of the Einstein tensor

Author: Gawlik, Evan S. and Neunteufel, Michael
Subjects: Mathematics - Numerical Analysis, Mathematics - Differential Geometry, 65N30 (Primary) 53A70, 83C27 (Secondary)
Abstract: We construct and analyze finite element approximations of the Einstein tensor in dimension $N \ge 3$. We focus on the setting where a smooth Riemannian metric tensor $g$ on a polyhedral domain $\Omega \subset \mathbb{R}^N$ has been approximated by a piecewise polynomial metric $g_h$ on a simplicial triangulation $\mathcal{T}$ of $\Omega$ having maximum element diameter $h$. We assume that $g_h$ possesses single-valued tangential-tangential components on every codimension-1 simplex in $\mathcal{T}$. Such a metric is not classically differentiable in general, but it turns out that one can still attribute meaning to its Einstein curvature in a distributional sense. We study the convergence of the distributional Einstein curvature of $g_h$ to the Einstein curvature of $g$ under refinement of the triangulation. We show that in the $H^{-2}(\Omega)$-norm, this convergence takes place at a rate of $O(h^{r+1})$ when $g_h$ is an optimal-order interpolant of $g$ that is piecewise polynomial of degree $r \ge 1$. We provide numerical evidence to support this claim., Comment: arXiv admin note: text overlap with arXiv:2301.02159
Published: 2023

19. Mitigating risks and maximizing sustainability of treated wastewater reuse for irrigation.

Author: Klapp, Iftach, Korach-Rechtman, Hila, Kurtzman, Daniel, Levy, Guy, Maffettone, Roberta, Malato, Sixto, Manaia, Célia, Manoli, Kyriakos, Moshe, Orah, Rimelman, Andrew, Rizzo, Luigi, Sedlak, David, Shnit-Orland, Maya, Shtull-Trauring, Eliav, Tarchitzky, Jorge, Welch-White, Venus, Williams, Clinton, McLain, Jean, Cytryn, Eddie, Yalin, David, Craddock, Hillary, Assouline, Shmuel, Ben Mordechay, Evyatar, Ben-Gal, Alon, Bernstein, Nirit, Chaudhry, Rabia, Chefetz, Benny, Fatta-Kassinos, Despo, Gawlik, Bernd, Hamilton, Kerry, Khalifa, Leron, and Kisekka, Isaya
Subjects: Agronomic and environmental risks, Contaminants of emerging concern, Policy and outreach, Treated wastewater irrigation, Wastewater treatment processes
Abstract: Scarcity of freshwater for agriculture has led to increased utilization of treated wastewater (TWW), establishing it as a significant and reliable source of irrigation water. However, years of research indicate that if not managed adequately, TWW may deleteriously affect soil functioning and plant productivity, and pose a hazard to human and environmental health. This review leverages the experience of researchers, stakeholders, and policymakers from Israel, the United-States, and Europe to present a holistic, multidisciplinary perspective on maximizing the benefits from municipal TWW use for irrigation. We specifically draw on the extensive knowledge gained in Israel, a world leader in agricultural TWW implementation. The first two sections of the work set the foundation for understanding current challenges involved with the use of TWW, detailing known and emerging agronomic and environmental issues (such as salinity and phytotoxicity) and public health risks (such as contaminants of emerging concern and pathogens). The work then presents solutions to address these challenges, including technological and agronomic management-based solutions as well as source control policies. The concluding section presents suggestions for the path forward, emphasizing the importance of improving links between research and policy, and better outreach to the public and agricultural practitioners. We use this platform as a call for action, to form a global harmonized data system that will centralize scientific findings on agronomic, environmental and public health effects of TWW irrigation. Insights from such global collaboration will help to mitigate risks, and facilitate more sustainable use of TWW for food production in the future.
Published: 2023

20. Methodology for Testing the Uniformity of the Composition of a Batch of Polymer Materials on the Example of Sbr Rubber Granulates in the Aspect of Potential Applications

Author: Beata Grynkiewicz-Bylina, Bożena Rakwic, Monika Gawlik-Jędrysiak, Małgorzata Szymiczek, and Błażej Chmielnicki
Subjects: recycling, rubber granulate, polymer materials, physicomechanical properties, batch composition homogeneity, styrene-butadiene rubber, Engineering (General). Civil engineering (General), TA1-2040
Abstract: This publication presents a comprehensive method for assessing the homogeneity of the composition of a large batch of polymer materials, with a mass of 1.5 tons, consisting of 60 transport packages, using the example of rubber granulate from recycled car tires. The presented method combines statistical analysis tools used to determine the samples number to be taken from the batch and the pyrolytic thermal desorption technique coupled with gas chromatography-mass spectrometry (Py/TD-GC-MS), used for material identification. Directions for improving the method for the quantitative identification of batch components are also indicated. The developed method can be applied to assess the purity of batches of recycled rubber granulate used in the construction of sports field surfaces and to determine the content of substances harmful to the environment and human health, such as polycyclic aromatic hydrocarbons. The direction for improving the developed spot-check control method using an alternative approach is to supplement it with a quantitative assessment of batch parameters in relation to the threshold values, such as tolerance limits.
Published: 2024
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21. Terahertz conductivity mapping of thin films on smart textiles

Author: Alexander Jäckel, Maximilian L. Hupfer, Enrique Castro-Camus, Daniel M. Mittleman, Gabriele Schmidl, Annett Gawlik, Jonathan Plentz, and Martin Koch
Subjects: Medicine, Science
Abstract: Abstract Smart textiles that promise to become sensors and actuators for multiple applications are an active area of research. Conductive textiles formed by coating a fabric with a conductive film will play a key role in such applications. Here we present contactless mapping of the terahertz (THz) conductivity of thin conductive films deposited on textiles. These conductivity maps enable non-destructive assessment of the conductivity of such layers and therefore the identification and localization of non-uniformities in local conductivity. The THz measurements are quantitatively consistent with four-point probe measurements of the same areas.
Published: 2024
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22. Measurement of the energy-differential cross-section of the 12C(n,p)12B and 12C(n,d)11B reactions at the n_TOF facility at CERN

Author: Barbagallo M., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Bennett S., Berthoumieux E., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D, Casanovas A., Cerutti F., Chiaveri E., Colonna N., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Davies P. J., Diakaki M., Dietz M., Domingo-Pardo C, Dressler R., Ducasse Q., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P. F., Mastromarco M., Maugeri E., Mazzone A., Mendoza E., Mengoni A., Michalopoulou V., Milazzo P. M., Millán-Callado M. A., Mingrone F., Moreno-Soto J, Musumarra A., Negret A., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J. M., Ramos Doval D., Reifarth R., Rochman D., Rubbia C., Sabaté- Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sekhar A., Smith A. G., Sosnin N., Sprung P., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeño-Saldivia A. E., Tassan-Got L, Thomas B., Torres-Sánchez P., Tsinganis A., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: Although the 12C(n,p)12B and 12C(n,d)11B reactions are of interest in several fields of basic and applied Nuclear Physics the present knowledge of these two cross-sections is far from being accurate and reliable, with both evaluations and data showing sizable discrepancies. As part of the challenging n_TOF program on (n,cp) nuclear reactions study, the energy differential cross-sections of the 12C(n,p)12B and 12C(n,d)11 B reactions have been measured at CERN from the reaction thresholds up to 30 MeV neutron energy. Both measurements have been recently performed at the long flight-path (185 m) experimental area of the n_TOF facility at CERN using a pure (99.95%) rigid graphite target and two silicon telescopes. In this paper an overview of the experiment is presented together with a few preliminary results.
Published: 2020
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23. Measurement and analysis of 155,157Gd(n,γ) from thermal energy to 1 keV

Author: Massimi C., Aberle O., Andrzejewski J., Audouin L., Bacak M., Balibrea J., Barbagallo M., Bečvář F., Berthoumieux E., Billowes J., Bosnar D., Brown A., Caamaño M., Calviño F., Calviani M., Cano-Ott D, Cardella R., Casanovas A., Castelluccio D. M., Cerutti F., Chen Y. H., Chiaveri E., Clai G., Colonna N., Console Camprini P., Cortés G., Cortés-Giraldo M. A., Cosentino L., Damone L. A., Diakaki M., Domingo-Pardo C, Dressler R., Dupont E., Durán I., Fernández-Domínguez B., Ferrari A., Ferreira P., Finocchiaro P., Furman V., Göbel K., García A. R., Gawlik A., Gilardoni S., Glodariu T., Gonçalves I. F., González-Romero E., Griesmayer E., Guerrero C., Guglielmelli A., Gunsing F., Harada H., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Käppeler F., Kadi Y., Kalamara A., Kavrigin P., Kimura A., Kivel N., Knapova I., Kokkoris M., Krtička M., Kurtulgil D., Leal-Cidoncha E, Lederer C., Leeb H., Lerendegui-Marco J, Lonsdale S. J., Macina D., Manna A., Marganiec J., Martínez T., Masi A., Mastinu P., Mastromarco M., Maugeri E. A., Mazzone A., Mendoza E., Mengoni A., Milazzo P. M., Mingrone F., Mucciola R., Musumarra A., Negret A., Nolte R., Oprea A., Patronis N., Pavlik A., Perkowski J., Porras I., Praena J., Quesada J. M., Radeck D., Rauscher T., Reifarth R., Rocchi F., Rubbia C., Ryan J. A., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sedyshev P., Smith A. G., Sosnin N. V., Stamatopoulos A., Tagliente G., Tain J. L, Tarifeño-Saldivia A., Tassan-Got L, Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vlachoudis V., Vlastou R., Wallner A., Warren S., Weiss C., Woods P. J., Wright T., and Žugec P.
Subjects: Physics, QC1-999
Abstract: We have measured the capture cross section of the 155Gd and 157Gd isotopes between 0.025 eV and 1 keV. The capture events were recorded by an array of 4 C6D6 detectors, and the capture yield was deduced exploiting the total energy detection system in combination with the Pulse Height Weighting Techniques. Because of the large cross section around thermal neutron energy, 4 metallic samples of different thickness were used to prevent problems related to self-shielding. The samples were isotopically enriched, with a cross contamination of the other isotope of less than 1.14%. The capture yield was analyzed with an R-Matrix code to describe the cross section in terms of resonance parameters. Near thermal energies, the results are significantly different from evaluations and from previous time-of-flight experiments. The data from the present measurement at n_TOF are publicly available in the experimental nuclear reaction database EXFOR.
Published: 2020
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24. First results of the 241Am(n,f) cross section measurement at the Experimental Area 2 of the n_TOF facility at CERN

Author: Eleme Z., Patronis N., Stamatopoulos A., Tsinganis A., Kokkoris M., Michalopoulou V., Diakaki M., Vlastou R., Tassan-Got L, Colonna N., Heyse J., Barbagallo M., Mastromarco M., Macina D., Chiaveri E., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Bennett S., Berthoumieux E., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D, Casanovas A., Cerutti F., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Davies P. J., Dietz M., Domingo-Pardo C, Dressler R., Ducasse Q., Dupont E., Durán I., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Jenkins D. G., Jericha E., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kopatch Y., Krticˇka M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lonsdale S. J., Manna A., Martínez T., Masi A., Massimi C., Mastinu P. F., Maugeri E., Mazzone A., Mendoza E., Mengoni A., Milazzo P. M., Millán-Callado M. A., Mingrone F., Moreno-Soto J, Musumarra A., Negret A., Ogállar F., Oprea A., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J. M., Ramos Doval D., Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sekhar A., Smith A. G., Sosnin N., Sprung P., Tagliente G., Tain J. L., Tarifeño-Saldivia A. E., Thomas B., Torres-Sánchez P., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: Feasibility, design and sensitivity studies on innovative nuclear reactors that could address the issue of nuclear waste transmutation using fuels enriched in minor actinides, require high accuracy cross section data for a variety of neutron-induced reactions from thermal energies to several tens of MeV. The isotope 241Am (T1/2= 433 years) is present in high-level nuclear waste (HLW), representing about 1.8 % of the actinide mass in spent PWR UOx fuel. Its importance increases with cooling time due to additional production from the β-decay of 241Pu with a half-life of 14.3 years. The production rate of 241 Am in conventional reactors, including its further accumulation through the decay of 241Pu and its destruction through transmutation/incineration are very important parameters for the design of any recycling solution. In the present work, the 241 Am(n,f) reaction cross-section was measured using Micromegas detectors at the Experimental Area 2 of the n_TOF facility at CERN. For the measurement, the 235U(n,f) and 238U(n,f) reference reactions were used for the determination of the neutron flux. In the present work an overview of the experimental setup and the adopted data analysis techniques is given along with preliminary results.
Published: 2020
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25. Accurate measurement of the standard 235U(n,f) cross section from thermal to 170 keV neutron energy

Author: Amaducci S., Aberle O., Andrzejewski J., Audouin L., Bacak M., Balibrea J., Barbagallo M., Bečvář F., Berthoumieux E., Billowes J., Bosnar D., Brown A., Caamaño M., Calviño F., Calviani M., Cano-Ott D, Cardella R., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G., Cortés-Girardo M. A., Cosentino L., Damone L. A., Diakaki M., Domingo-Pardo C, Dressler R., Dupont E., Durán I., Fernández-Domínguez B., Ferrari A., Ferreira P., Finocchiaro P., Furman V., Göbel K., García A. R., Gawlik A., Gilardoni S., Glodariu T., Gonçalves I. F., González-Romero E., Griesmayer E., Guerrero C., Gunsing F., Harada H., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Käppeler F., Kadi Y., Kalamara A., Kavrigin P., Kimura A., Kivel N., Knapova I., Kokkoris M., Krtička M., Kurtulgil D., Leal-Cidoncha E, Lederer C., Leeb H., Lerendegui-Marco J, Lo Meo S., Lonsdale S. J., Macina D., Manna A., Marganiec J., Martínez T., Masi A., Massimi C., Mastinu P., Mastromarco M., Maugeri E. A., Mazzone A., Mendoza E., Mengoni A., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Oprea A., Patronis N., Pavlik A., Perkowski J., Porras I., Praena J., Quesada J. M., Radeck D., Rauscher T., Reifarth R., Rubbia C., Ryan J. A., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sedyshev P., Smith A. G., Sosnin N. V., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeño-Saldivia A., Tassan-Got L, Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vlachoudis V., Vlastou R., Wallner A., Warren S., Weiss C., Woods P. J., Wright T., and Žugec P.
Subjects: Physics, QC1-999
Abstract: An accurate measurement of the 235U(n,f) cross section from thermal to 170 keV of neutron energy has recently been performed at n_TOF facility at CERN using 6Li(n,t)4He and 10B(n,α)7Li as references. This measurement has been carried out in order to investigate a possible overestimation of the 235U fission cross section evaluation provided by most recent libraries between 10 and 30 keV. A custom experimental apparatus based on in-beam silicon detectors has been used, and a Monte Carlo simulation in GEANT4 has been employed to characterize the setup and calculate detectors efficiency. The results evidenced the presence of an overestimation in the interval between 9 and 18 keV and the new data may be used to decrease the uncertainty of 235U(n,f) cross section in the keV region.
Published: 2020
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26. Status and perspectives of the neutron time-of-flight facility n_TOF at CERN

Author: Chiaveri E., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V., Bacak M., Barbagallo M., Bennett S., Berthoumieux E., Bosnar D., Brown A.S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D., Casanovas A., Cerutti F., Colonna N., Cortés G.P., Cortés-Giraldo M.A., Cosentino L., Cristallo S., Damone L.A., Davies P.J., Diakaki M., Dietz M., Domingo-Pardo C., Dressler R., Ducasse Q., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D.G., Jericha E., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C., Lerendegui-Marco J., Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P.F., Mastromarco M., Maugeri E., Mazzone A., Mendoza E., Mengoni A., Michalopoulou V., Milazzo P.M., Millán-Callado M.A., Mingrone F., Moreno-Soto J., Musumarra A., Negret A., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J.M., Ramos Doval D., Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sekhar A., Smith A.G., Sosnin N., Sprung P., Stamatopoulos A., Tagliente G., Tain J.L., Tarifeño-Saldivia A.E., Tassan-Got L., Thomas B., Torres-Sánchez P., Tsinganis A., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Woods P.J., Wright T.J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: Since the start of its operation in 2001, based on an idea of Prof. Carlo Rubbia [1], the neutron time of-flight facility of CERN, n_TOF, has become one of the most forefront neutron facilities in the world for wide-energy spectrum neutron cross section measurements. Thanks to the combination of excellent neutron energy resolution and high instantaneous neutron flux available in the two experimental areas, the second of which has been constructed in 2014, n_TOF is providing a wealth of new data on neutron-induced reactions of interest for nuclear astrophysics, advanced nuclear technologies and medical applications. The unique features of the facility will continue to be exploited in the future, to perform challenging new measurements addressing the still open issues and long-standing quests in the field of neutron physics. In this document the main characteristics of the n_TOF facility and their relevance for neutron studies in the different areas of research will be outlined, addressing the possible future contribution of n_TOF in the fields of nuclear astrophysics, nuclear technologies and medical applications. In addition, the future perspectives of the facility will be described including the upgrade of the spallation target, the setup of an imaging installation and the construction of a new irradiation area.
Published: 2020
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27. Study of the neutron-induced fission cross section of 237Np at CERN's n_TOF facility over a wide energy range

Author: Stamatopoulos A., Tsinganis A., Diakaki M., Colonna N., Kokkoris M., Vlastou R., Kalamara A., Schillebeeckx P., Tassan-Got L, Žugec P., Sabaté-Gilarte M., Patronis N., Eleme Z., Heyse J., Aberle O., Andrzejewski J., Audouin L., Bacak M., Balibrea J., Barbagallo M., Bečvář F., Berthoumieux E., Billowes J., Bosnar D., Brown A., Caamaño M., Calviño F., Calviani M., Cano-Ott D, Cardella R., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Cortés G., Cortés-Giraldo M. A., Cosentino L., Damone L. A., Domingo-Pardo C, Dressler R., Dupont E., Durán, Femandez-Domínguez B., Ferrari A., Ferreira P., Finocchiaro P., Furman V., Göbel K., García A. R., Gawlik A., Gilardoni S., Glodariu† T., Gonçalves I. F., González-Romero E., Griesmayer E., Guerrero C., Gunsing F., Harada H., Heinitz S., Jenkins D. G., Jericha E., Käppeler F., Kadi Y., Kavrigin P., Kimura A., Kivel N., Knapova I., Krtička M., Kurtulgil D., Leal-Cidoncha E, Lederer C., Leeb H., Lerendegui-Marco J, Meo S. Lo, Lonsdale S. J., Macina D., Manna A., Marganiec J., Martínez T., Masi A., Massimi C., Mastinu P., Mastromarco M., Maugeri E. A., Mazzone A., Mendoza E., Mengoni A., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Oprea A., Pavlik A., Perkowski J., Porras I., Praena J., Quesada J. M., Radeck D., Rauscher T., Reifarth R., Rubbia C., Ryan J. A., Saxena A., Schumann D., Sedyshev P., Smith A. G., Sosnin N. V., Tagliente G., Tain J. L., Tarifeño-Saldivia A., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Wallner A., Warren S., Weiss C., Woods P. J., and Wright T.
Subjects: Physics, QC1-999
Abstract: Neutron-induced fission cross sections of isotopes involved in the nuclear fuel cycle are vital for the design and safe operation of advanced nuclear systems. Such experimental data can also provide additional constraints for the adjustment of nuclear model parameters used in the evaluation process, resulting in the further development of fission models. In the present work, the 237Np(n,f) cross section was studied at the EAR2 vertical beam-line at CERN's n_TOF facility, over a wide range of neutron energies, from meV to MeV, using the time-of-flight technique and a set-up based on Micromegas detectors, in an attempt to provide accurate experimental data. Preliminary results in the 200 keV – 14 MeV neutron energy range as well as the experimental procedure, including a description of the facility and the data handling and analysis, will be presented.
Published: 2020
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28. The 154Gd neutron capture cross section measured at the n_TOF facility and its astrophysical implications

Author: Mastromarco M., Mazzone A., Massimi C., Cristallo S., Colonna N., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Barbagallo M., Bennett S., Berthoumieux E., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D, Casanovas A., Cerutti F., Chiaveri E., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Damone L. A., Davies P. J., Diakaki M., Dietz M., Domingo-Pardo C, Dressler R., Ducasse Q., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Mastinu P. F., Maugeri E., Mendoza E., Mengoni A., Michalopoulou V., Milazzo P. M., Millán-Callado M. A., Mingrone F., Moreno-Soto J, Musumarra A., Negret A., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J. M., Doval D. Ramos, Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sekhar A., Smith A. G., Sosnin N., Sprung P., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeño-Saldivia A. E., Tassan-Got L, Thomas B., Torres-Sánchez P., Tsinganis A., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: The (n, γ) cross sections of the gadolinium isotopes play an important role in the study of the stellar nucleosynthesis. In particular, among the isotopes heavier than Fe, 154Gd together with 152Gd have the peculiarity to be mainly produced by the slow capture process, the so-called s-process, since they are shielded against the β-decay chains from the r-process region by their stable samarium isobars. Such a quasi pure s-process origin makes them crucial for testing the robustness of stellar models in galactic chemical evolution (GCE). According to recent models, the 154Gd and 152Gd abundances are expected to be 15-20% lower than the reference un-branched s-process 150Sm isotope. The close correlation between stellar abundances and neutron capture cross sections prompted for an accurate measurement of 154Gd cross section in order to reduce the uncertainty attributable to nuclear physics input and eventually rule out one of the possible causes of present discrepancies between observation and model predictions. To this end, the neutron capture cross section of 154Gd was measured in a wide neutron energy range (from thermal up to some keV) with high resolution in the first experimental area of the neutron time-of-flight facility n_TOF (EAR1) at CERN. In this contribution, after a brief description of the motivation and of the experimental setup used in the measurement, the preliminary results of the 154Gd neutron capture reaction as well as their astrophysical implications are presented.
Published: 2020
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29. Preliminary results on the 233U α-ratio measurement at n_TOF

Author: Bacak M., Aïche M., Bélier G., Berthoumieux E., Diakaki M., Dupont E., Gunsing F., Heyse J., Kopecky S., Krtička M., Laurent B., Leeb H., Mathieu L., Schillebeeckx P., Serot O., Taieb J., Valenta S., Vlachoudis V., Aberle O., Andrzejewski J., Audouin L., Balibrea J., Barbagallo M., Bečvář F., Billowes J., Bosnar D., Brown A., Caamaño M., Calviño F., Calviani, Cano-Ott D, Cardella R., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna, Cortés G., Cortés-Giraldo M. A., Cosentino L., Damone L. A., Domingo-Pardo C, Dressler R., Durán I., Fernández-Domínguez B., Ferrari A., Ferreira P., Finocchiaro P., Furman V., Göbel K., García A. R., Gawlik A., Gilardoni S., Glodariu T., Gonçalves I. F., González-Romero E., Griesmayer E., Guerrero C., Harada H., Heinitz S., Jenkins D. G., Jericha E., Käppeler F., Kadi Y., Kalamara A., Kavrigin P., Kimura A., Kivel N., Knapova I., Kokkoris M., Kurtulgil D., Leal-Cidoncha E, Lederer C., Lerendegui-Marco J, Meo S. Lo, Lonsdale S. J., Macina D., Manna A., Marganiec J., Martínez T., Masi A., Massimi C., Mastinu P., Mastromarco M., Maugeri E. A., Mazzone A., Mendoza E., Mengoni A., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Oprea A., Patronis N., Pavlik A., Perkowski J., Porras I., Praena J., Quesada J. M., Radeck D., Rauscher T., Reifarth R., Rubbia C., Ryan J. A., Sabaté-Gilarte M., Saxena A., Schumann D., Sedyshev P., Smith A. G., Sosnin N. V., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeño-Saldivia A., Tassan-Got L, Vannini G., Variale V., Vaz P., Ventura A., Vlastou R., Wallner A., Warren S., Weiss C., Woods P. J., Wright T., and Žugec P.
Subjects: Physics, QC1-999
Abstract: 233U is the fissile nuclei in the Th-U fuel cycle with a particularily small neutron capture cross setion which is on average about one order of magnitude lower than its fission cross section. Hence, the measurement of the 233U(n, γ) cross section relies on a method to accurately distinguish between capture and fission γ-rays. A measurement of the 233U α-ratio has been performed at the n_TOF facility at CERN using a so-called fission tagging setup, coupling n_TOF 's Total Absorption Calorimeter with a novel fission chamber to tag the fission γ-rays. The experimental setup is described and essential parts of the analysis are discussed. Finally, a preliminary 233U α-ratio is presented.
Published: 2020
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30. Setup for the measurement of the 235U(n, f) cross section relative to n-p scattering up to 1 GeV

Author: Manna A., Aberle O., Alcayne V, Amaducci S., Andrzejewski J., Audouin L., Babiano V-Suarez, Bacak M., Barbagallo M., Bennett S., Berthoumieux E., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calvi Fño, Cano-Ott D, Casanovas A., Cerutti F., Chiaveri E., Colonna N., Cortés G. P., Cortés-Giraldo M. A., Coséntino L., Cristallo S., Damone L. A., Davies P. J., Diakaki M., Dietz M., Domingo-Pardo C, Dressler R., Ducasse Q., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Goncalves I, Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F, Heinitz S., Heyse J., Jenkins D. G., Jericha E., Jiri U., Junghans A., Kadi Y, Käppeler F, Kimura A., Knapová I., Kokkoris M., Kopatch Y., Krtiička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lonsdale S.-J., Macina D., Martínez T, Masi A., Massimi C., Mastinu P. F, Mastromarco M., Maugeri E., Mazzone A., Mendoza E., Mengoni A., Michalopoulou V, Milazzo P. M., Millán-Callado M. A., Mingrone F, Moreno-Soto J, Musumarra A., Negret A., Nolte R., Ogállar F, Oprea A., Patronis N., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J.M., Ramos D., Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sekhar A., Smith A.G., Sosnin N., Sprung P., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeno-Saldivia A. E., Tassan-Got L, Thomas B., Torres-Sánchez P., Tsinganis A., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V, Vlastou R., Wallner A., Woods P. J., Wright T J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: The neutron induced fission of 235U is extensively used as a reference for neutron fluence measurements in various applications, ranging from the investigation of the biological effectiveness of high energy neutrons, to the measurement of high energy neutron cross sections of relevance for accelerator driven nuclear systems. Despite its widespread use, no data exist on neutron induced fission of 235U above 200 MeV. The neutron facility n_TOF offers the possibility to improve the situation. The measurement of 235U(n,f) relative to the differential n-p scattering cross-section, was carried out in September 2018 with the aim of providing accurate and precise cross section data in the energy range from 10 MeV up to 1 GeV. In such measurements, Recoil Proton Telescopes (RPTs) are used to measure the neutron flux while the fission events are detected and counted with dedicated detectors. In this paper the measurement campaign and the experimental set-up are illustrated.
Published: 2020
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31. Neutron capture cross section measurements of 241Am at the n_TOF facility

Author: Oprea A., Gunsing F., Schillebeeckx P., Aberle O., Bacak M., Berthoumieux E., Cano-Ott D, Diakaki M., Dupont E., Geslot B., Glodariu T., Heyse J., Mendoza E., Negret A., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Bécares V., Babiano-Suarez V, Barbagallo M., Becčvář F., Bellia G., Billowes J., Bosnar D., Brown A., Busso M., Caamaño M., Caballero-Ontanaya L, Calviño F., Calviani M., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Dietz M., Domingo-Pardo C, Dressler R., Durán I., Eleme Z., Femández-Domínguez B., Ferrari A., Finocchiaro P., Furman V., Göbel K., Garg R., Gawlik A., Gilardoni S., Goncalves I. F., González-Romero E., Guerrero C., Harada H., Heinitz S., Jenkins D. G., Jericha E., Käppeler F., Kadi Y., Kimura A., Kivel N., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Meo S. Lo, Lonsdale S. J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P., Mastromarco M., Matteucci F., Maugeri E. A., Mazzone A., Mengoni A., Michalopoulou V., Milazzo P. M., Mingrone F., Musumarra A., Nolte R., Ogállar F., Patronis N., Pavlik A., Perkowski J., Persanti L., Porras I., Praena J., Quesada J. M., Radeck D., Ramos-Doval D, Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schumann D., Smith A. G., Sosnin N. V., Stamatopoulos A., Tagliente G., Tain J. L., Talip T., Tarifeño-Saldivia A., Tassan-Got L, Torres-Sánchez P., Tsinganis A., Ulrich J., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T., and Žugec P.
Subjects: Physics, QC1-999
Abstract: Neutron capture on 241Am plays an important role in the nuclear energy production and also provides valuable information for the improvement of nuclear models and the statistical interpretation of the nuclear properties. A new experiment to measure the 241Am(n, γ) cross section in the thermal region and the first few resonances below 10 eV has been carried out at EAR2 of the n_TOF facility at CERN. Three neutron-insensitive C6D6 detectors have been used to measure the neutron-capture gamma cascade as a function of the neutron time of flight, and then deduce the neutron capture yield. Preliminary results will be presented and compared with previously obtained results at the same facility in EAR1. In EAR1 the gamma-ray background at thermal energies was about 90% of the signal while in EAR2 is up to a 25 factor much more favorable signal to noise ratio. We also extended the low energy limit down to subthermal energies. This measurement will allow a comparison with neutron capture measurements conducted at reactors and using a different experimental technique.
Published: 2020
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32. New reaction rates for the destruction of 7Be during big bang nucleosynthesis measured at CERN/n_TOF and their implications on the cosmological lithium problem

Author: Mengoni A., Damone L.A., Barbagallo M., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Bennett S., Berthoumieux E., Bosnar D., Brown A.S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D, Casanovas A., Cerutti F., Chiaveri E., Colonna N., Cortés G.P., Cortés-Giraldo M.A., Cosentino L., Cristallo S., Davies P.J., Diakaki M., Dietz M., Domingo-Pardo C, Dressler R., Ducasse Q., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D.G., Jericha E., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P.F., Mastromarco M., Maugeri E., Mazzone A., Mendoza E., Michalopoulou V., Milazzo P.M., Millán-Callado M.A., Mingrone F., Moreno-Soto J, Musumarra A., Negret A., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J.M., Doval D. Ramos, Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sekhar A., Smith A.G., Sosnin N., Sprung P., Stamatopoulos A., Tagliente G., Tain J.L., Tarifeño-Saldivia A.E., Tassan-Got L, Thomas B., Torres-Sánchez P., Tsinganis A., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Woods P.J., Wright T.J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: New measurements of the 7Be(n,α)4He and 7Be(n,p)7Li reaction cross sections from thermal to keV neutron energies have been recently performed at CERN/n_TOF. Based on the new experimental results, astrophysical reaction rates have been derived for both reactions, including a proper evaluation of their uncertainties in the thermal energy range of interest for big bang nucleosynthesis studies. The new estimate of the 7Be destruction rate, based on these new results, yields a decrease of the predicted cosmological 7Li abundance insufficient to provide a viable solution to the cosmological lithium problem.
Published: 2020
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33. Measurement of the 244Cm capture cross sections at both CERN n_TOF experimental areas

Author: Alcayne V., Mendoza E., Cano-Ott D, Kimura A., Aberle O., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Barbagallo M., Bécares V., Bečvář F., Bellia G., Berthoumieux E., Billowes J., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Diakaki M., Dietz M., Domingo-Pardo C, Dressler R., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Glodariu T., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Kadi Y., Käppeler F., Kivel N., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lo Meo S., Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P. F., Mastromarco M., Matteucci F., Maugeri E., Mazzone A., Mengoni A., Michalopoulou V., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Piersanti L., Porras I., Praena J., Quesada J. M., Radeck D., Ramos Doval D., Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Smith A. G., Sosnin N., Stamatopoulos A., Tagliente G., Tain J. L., Talip Z., Tarifeño-Saldivia A. E., Tassan-Got L, Torres-Sánchez P., Tsinganis A., Ulrich J., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: Accurate neutron capture cross section data for minor actinides (MAs) are required to estimate the production and transmutation rates of MAs in light water reactors with a high burnup, critical fast reactors like Gen-IV systems and other innovative reactor systems such as accelerator driven systems (ADS). Capture reactions of 244Cm open the path for the formation of heavier Cm isotopes and of heavier elements such as Bk and Cf. In addition, 244Cm shares nearly 50% of the total actinide decay heat in irradiated reactor fuels with a high burnup, even after three years of cooling. Experimental data for this isotope are very scarce due to the difficulties of providing isotopically enriched samples and because the high intrinsic activity of the samples requires the use of neutron facilities with high instantaneous flux. The only two previous experimental data sets for this neutron capture cross section have been obtained in 1969 using a nuclear explosion and, more recently, at J-PARC in 2010. The neutron capture cross sections have been measured at n_TOF with the same samples that the previous experiments in J-PARC. The samples were measured at n_TOF Experimental Area 2 (EAR-2) with three C6D6 detectors and also in Experimental Area 1 (EAR-1) with the Total Absorption Calorimeter (TAC). Preliminary results assessing the quality and limitations of these new experimental datasets are presented for the experiments in both areas. Preliminary yields of both measurements will be compared with evaluated libraries for the first time.
Published: 2020
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34. Measurement of the 242Pu(n, γ) cross section from thermal to 500 keV at the Budapest research reactor and CERN n_TOF-EAR1 facilities

Author: Lerendegui-Marco J, Guerrero C., Mendoza E., Quesada J. M., Eberhardt K., Junghans A., Krtiička M., Belgya T., Maróti B., Aberle O., Andrzejewski J., Audouin L., Bécares V., Bacak M., Balibrea J., Barbagallo M., Barros S., Bečvář F., Beinrucker C., Berthoumieux E., Billowes J., Bosnar D., Brugger M., Caamaño M., Calviño F., Calviani M., Cano-Ott D, Cardella R., Casanovas A., Castelluccio D. M., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G., Cortés-Giraldo M. A., Cosentino L., Damone L. A., Diakaki M., Domingo-Pardo C, Dressler R., Dupont E., Durán I., Fernández-Domínguez B., Ferrari A., Ferreira P., Finocchiaro P., Furman V., Göbel K., García A. R., Gawlik A., Glodariu T., Gonçalves I. F., González-Romero E., Goverdovski A., Griesmayer E., Gunsing F., Harada H., Heftrich T., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Käppeler F., Kadi Y., Katabuchi T., Kavrigin P., Ketlerov V., Khryachkov V., Kimura A., Kivel N., Knapova I., Kokkoris M., Leal-Cidoncha E, Lederer C., Leeb H., Lo Meo S., Lonsdale S. J., Losito R., Macina D., Marganiec J., Martínez T., Massimi C., Mastinu P., Mastromarco M., Matteucci F., Maugeri E. A., Mengoni A., Milazzo P. M., Mingrone F., Mirea M., Montesano S., Musumarra A., Nolte R., Oprea A., Patronis N., Pavlik A., Perkowski J., Porras J. I., Praena J., Rajeev K., Rauscher T., Reifarth R., Riego-Perez A, Rout P. C., Rubbia C., Ryan J. A., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schmidt S., Schumann D., Sedyshev P., Smith A. G., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeño-Saldivia A., Tassan-Got L, Tsinganis A., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Warren S., Weigand M., Weiss C., Wolf C., Woods P. J., Wright T., and Žugec P.
Subjects: Physics, QC1-999
Abstract: The design and operation of innovative nuclear systems requires a better knowledge of the capture and fission cross sections of the Pu isotopes. For the case of capture on 242Pu, a reduction of the uncertainty in the fast region down to 8-12% is required. Moreover, aiming at improving the evaluation of the fast energy range in terms of average parameters, the OECD NEA High Priority Request List (HPRL) requests high-resolution capture measurements with improved accuracy below 2 keV. The current uncertainties also affect the thermal point, where previous experiments deviate from each other by 20%. A fruitful collaboration betwen JGU Mainz and HZ Dresden-Rossendorf within the EC CHANDA project resulted in a 242Pu sample consisting of a stack of seven fission-like targets making a total of 95(4) mg of 242Pu electrodeposited on thin (11.5 μm) aluminum backings. This contribution presents the results of a set of measurements of the 242Pu(n, γ) cross section from thermal to 500 keV combining different neutron beams and techniques. The thermal point was determined at the Budapest Research Reactor by means of Neutron Activation Analysis and Prompt Gamma Analysis, and the resolved (1 eV - 4 keV) and unresolved (1 - 500 keV) resonance regions were measured using a set of four Total Energy detectors at the CERN n_TOF-EAR1.
Published: 2020
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35. Study of photon strength functions of 241Pu and 245Cm from neutron capture measurements

Author: Mendoza E., Alcayne V., Cano-Ott D, Kimura A., Skarbeli A. V., Aberle O., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Barbagallo M., Bécares V., Bečvář F., Bellia G., Berthoumieux E., Billowes J., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Diakaki M., Dietz M., Domingo-Pardo C, Dressler R., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Glodariu T., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Kadi Y., Käppeler F., Kivel N., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Meo S. Lo, Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P. F., Mastromarco M., Matteucci F., Maugeri E., Mazzone A., Mengoni A., Michalopoulou V., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Piersanti L., Porras I., Praena J., Quesada J. M., Radeck D., Doval D. Ramos, Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Smith A. G., Sosnin N., Stamatopoulos A., Tagliente G., Tain J. L., Talip Z., Tarifeño-Saldivia A. E., Tassan-Got L, Torres-Sánchez P., Tsinganis A., Ulrich J., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: We have measured the γ-rays following neutron capture on 240Pu and 244 Cm at the n_TOF facility at CERN with the Total Absorption Calorimeter (TAC) and with C6D6 organic scintillators. The TAC is made of 40 BaF2 crystals operating in coincidence and covering almost the entire solid angle. This allows to obtain information concerning the energy spectra and the multiplicity of the measured capture γ-ray cascades. Additional information is also obtained from the C6D6 detectors. We have analyzed the measured data in order to draw conclusions about the Photon Strength Functions (PSFs) of 241Pu and 245Cm below their neutron separation energies. The analysis has been performed by fitting the PSFs to the experimental results, using the differential evolution method, in order to find neutron capture cascades capable of reproducing at the same time a great variety of deposited energy spectra.
Published: 2020
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36. Monte Carlo simulations and n-p differential scattering data measured with Proton Recoil Telescopes

Author: Terranova N., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Barbagallo M., Bennett S., Berthoumieux E., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D, Casanovas A., Cerutti F., Chiaveri E., Colonna N., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Davies P. J., Diakaki M., Dietz M., Domingo-Pardo C, Dressler R., Ducasse Q., Dupont E., Durán I., Eleme Z., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D. G., Jericha E., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lonsdale S.-J., Macina D., Manna A., Martínez T., Masi A., Massimi C., Mastinu P. F., Mastromarco M., Maugeri E., Mazzone A., Mendoza E., Mengoni A., Michalopoulou V., Milazzo P. M., Millán-Callado M. A., Mingrone F., Moreno-Soto J, Musumarra A., Negret A., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J. M., Doval D. Ramos, Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Sekhar A., Smith A. G., Sosnin N., Sprung P., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeño-Saldivia A. E., Tassan-Got L, Thomas B., Torres-Sánchez P., Tsinganis A., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: The neutron-induced fission cross section of 235U, a standard at thermal energy and between 0.15 MeV and 200 MeV, plays a crucial role in nuclear technology applications. The long-standing need of improving cross section data above 20 MeV and the lack of experimental data above 200 MeV motivated a new experimental campaign at the n_TOF facility at CERN. The measurement has been performed in 2018 at the experimental area 1 (EAR1), located at 185 m from the neutron-producing target (the experiment is presented by A. Manna et al. in a contribution to this conference). The 235U(n,f) cross section from 20 MeV up to about 1 GeV has been measured relative to the 1H(n,n)1H reaction, which is considered the primary reference in this energy region. The neutron flux impinging on the 235U sample (a key quantity for determining the fission events) has been obtained by detecting recoil protons originating from n-p scattering in a C2H4 sample. Two Proton Recoil Telescopes (PRT), consisting of several layers of solid-state detectors and fast plastic scintillators, have been located at proton scattering angles of 25.07° and 20.32°, out of the neutron beam. The PRTs exploit the ΔE-E technique for particle identification, a basic requirement for the rejection of charged particles from neutron-induced reactions in carbon. Extensive Monte Carlo simulations were performed to characterize proton transport through the different slabs of silicon and scintillation detectors, to optimize the experimental set-up and to deduce the efficiency of the whole PRT detector. In this work we compare measured data collected with the PRTs with a full Monte Carlo simulation based on the Geant-4 toolkit.
Published: 2020
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37. First results of the 230Th(n,f) cross section measurements at the CERN n_TOF facility

Author: Michalopoulou V., Stamatopoulos A., Vlastou R., Kokkoris M., Tsinganis A., Diakaki M., Eleme Z., Patronis N., Heyse J., Schillebeeckx P., Tassan-Got L, Barbagallo M., Colonna N., Urlass S., Macina D., Chiaveri E., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V, Bacak M., Bennett S., Berthoumieux E., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D, Casanovas A., Cerutti F., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Davies P. J., Dietz M., Domingo-Pardo C, Dressler R., Ducasse Q., Dupont E., Durán I., Femández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Jenkins D. G., Jericha E., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kopatch Y., Krtiička M., Kurtulgil D., Ladarescu I., Lederer-Woods C, Lerendegui-Marco J, Lonsdale S.-J., Manna A., Martínez T., Masi A., Massimi C., Mastinu P. F., Mastromarco M., Maugeri E., Mazzone A., Mendoza E., Mengoni A., Milazzo P. M., Millán-Callado M. A., Mingrone F., Moreno-Soto J, Musumarra A., Negret A., Ogállar F., Oprea A., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J. M., Ramos Doval D., Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schumann D., Sekhar A., Smith A. G., Sosnin N., Sprung P., Tagliente G., Tain J. L., Tarifeño-Saldivia A. E., Thomas B., Torres-Sánchez P., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: The study of neutron-induced reactions on actinides is of considerable importance for the design of advanced nuclear systems and alternative fuel cycles. Specifically, 230Th is produced from the α-decay of 234U as a byproduct of the 232Th/233U fuel cycle, thus the accurate knowledge of its fission cross section is strongly required. However, few experimental datasets exist in literature with large deviations among them, covering the energy range between 0.2 to 25 MeV. In addition, the study of the 230Th(n,f) cross-section is of great interest in the research on the fission process related to the structure of the fission barriers. Previous measurements have revealed a large resonance at En=715 keV and additional fine structures, but with high discrepancies among the cross-section values of these measurements. This contribution presents preliminary results of the 230Th(n,f) cross-section measurements at the CERN n_TOF facility. The high purity targets of the natural, but very rare isotope 230Th, were produced at JRC-Geel in Belgium. The measurements were performed at both experimental areas (EAR-1 and EAR-2) of the n_TOF facility, covering a very broad energy range from thermal up to at least 100 MeV. The experimental setup was based on Micromegas detectors with the 235U(n,f) and 238U(n,f) reaction cross-sections used as reference.
Published: 2020
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38. The Near Infrared Imager and Slitless Spectrograph for the James Webb Space Telescope -- I. Instrument Overview and in-Flight Performance

Author: Doyon, Rene, Willott, C. J, Hutchings, John B., Sivaramakrishnan, Anand, Albert, Loic, Lafreniere, David, Rowlands, Neil, Vila, M. Begona, Martel, Andre R., LaMassa, Stephanie, Aldridge, David, Artigau, Etienne, Cameron, Peter, Chayer, Pierre, Cook, Neil J., Cooper, Rachel A., Darveau-Bernier, Antoine, Dupuis, Jean, Earnshaw, Colin, Espinoza, Nestor, Filippazzo, Joseph C., Fullerton, Alexander W., Gaudreau, Daniel, Gawlik, Roman, Goudfrooij, Paul, Haley, Craig, Kammerer, Jens, Kendall, David, Lambros, Scott D., Ignat, Luminita Ilinca, Maszkiewicz, Michael, McColgan, Ashley, Morishita, Takahiro, Ouellette, Nathalie N. -Q., Pacifici, Camilla, Philippi, Natasha, Radica, Michael, Ravindranath, Swara, Rowe, Jason, Roy, Arpita, Saad, Karl, Sohn, Sangmo Tony, Talens, Geert Jan, Thatte, Deepashri, Taylor, Joanna M., Vandal, Thomas, Volk, Kevin, Wander, Michel, Warner, Gerald, Zheng, Sheng-Hai, Zhou, Julia, Abraham, Roberto, Beaulieu, Mathilde, Benneke, Bjorn, Ferrarese, Laura, Johnstone, Doug, Kaltenegger, Lisa, Meyer, Michael R., Pipher, Judy L., Rameau, Julien, Rieke, Marcia, Salhi, Salma, and Sawicki, Marcin
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The Near-Infrared Imager and Slitless Spectrograph (NIRISS) is the science module of the Canadian-built Fine Guidance Sensor (FGS) onboard the James Webb Space Telescope (JWST). NIRISS has four observing modes: 1) broadband imaging featuring seven of the eight NIRCam broadband filters, 2) wide-field slitless spectroscopy (WFSS) at a resolving power of $\sim$150 between 0.8 and 2.2 $\mu$m, 3) single-object cross-dispersed slitless spectroscopy (SOSS) enabling simultaneous wavelength coverage between 0.6 and 2.8 $\mu$m at R$\sim$700, a mode optimized for exoplanet spectroscopy of relatively bright ($J<6.3$) stars and 4) aperture masking interferometry (AMI) between 2.8 and 4.8 $\mu$m enabling high-contrast ($\sim10^{-3}-10^{-4}$) imaging at angular separations between 70 and 400 milliarcsec for relatively bright ($M<8$) sources. This paper presents an overview of the NIRISS instrument, its design, its scientific capabilities, and a summary of in-flight performance. NIRISS shows significantly better response shortward of $\sim2.5\,\mu$m resulting in 10-40% sensitivity improvement for broadband and low-resolution spectroscopy compared to pre-flight predictions. Two time-series observations performed during instrument commissioning in the SOSS mode yield very stable spectro-photometry performance within $\sim$10% of the expected noise. The first space-based companion detection of the tight binary star AB Dor AC through AMI was demonstrated.
Published: 2023

39. Terahertz conductivity mapping of thin films on smart textiles

Author: Jäckel, Alexander, Hupfer, Maximilian L., Castro-Camus, Enrique, Mittleman, Daniel M., Schmidl, Gabriele, Gawlik, Annett, Plentz, Jonathan, and Koch, Martin
Published: 2024
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40. EU surveys insights: analytical tools, future directions, and the essential requirement for reference materials in wastewater monitoring of SARS-CoV-2, antimicrobial resistance and beyond

Author: Paracchini, Valentina, Petrillo, Mauro, Arcot Rajashekar, Anandasagari, Robuch, Piotr, Vincent, Ursula, Corbisier, Philippe, Tavazzi, Simona, Raffael, Barbara, Suffredini, Elisabetta, La Rosa, Giuseppina, Gawlik, Bernd Manfred, and Marchini, Antonio
Published: 2024
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41. Thrombospondin-4 deletion does not exacerbate muscular dystrophy in β-sarcoglycan-deficient and laminin α2 chain-deficient mice

Author: Zarén, Paula and Gawlik, Kinga I.
Published: 2024
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42. Cell-particles interaction – selective uptake and transport of microdiamonds

Author: Ebrahimi, Armin M., Gawlik, Wojciech, Wojciechowski, Adam M., and Rajfur, Zenon
Published: 2024
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43. Finite Element Approximation of the Levi-Civita Connection and Its Curvature in Two Dimensions

Author: Berchenko-Kogan, Yakov and Gawlik, Evan S.
Published: 2024
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44. Preliminary results on the 233U capture cross section and alpha ratio measured at n_TOF (CERN) with the fission tagging technique

Author: Bacak M., Aiche M., Bélier G., Berthoumieux E., Diakaki M., Dupont E., Gunsing F., Heyse J., Kopecky S., Laurent B., Leeb H., Mathieu L., Schillebeeckx P., Serot O., Taieb J., Vlachoudis V., Aberle O., Andrzejewski J., Audouin L., Balibrea J., Barbagallo M., Bečvář F., Billowes J., Bosnar D., Brown A., Caamaño M., Calviño F., Calviani M., Cano-Ott D., Cardella R., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G., Cortés-Giraldo M. A., Cosentino L., Damone L. A., Domingo-Pardo C., Dressler R., Durán I., Fernández-Domínguez B., Ferrari A., Ferreira P., Finocchiaro P., Furman V., Göbel K., García A. R., Gawlik A., Gilardoni S., Glodariu T., Gonçalves I. F., González-Romero E., Griesmayer E., Guerrero C., Harada H., Heinitz S., Jenkins D. G., Jericha E., Käppeler F., Kadi Y., Kalamara A., Kavrigin P., Kimura A., Kivel N., Knapova I., Kokkoris M., Krtička M., Kurtulgil D., Leal-Cidoncha E., Lederer C., Lerendegui-Marco J., Meo S. Lo, Lonsdale S. J., Macina D., Manna A., Marganiec J., Martínez T., Masi A., Massimi C., Mastinu P., Mastromarco M., Maugeri E. A., Mazzone A., Mendoza E., Mengoni A., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Oprea A., Patronis N., Pavlik A., Perkowski J., Porras I., Praena J., Quesada J. M., Radeck D., Rauscher T., Reifarth R., Rubbia C., Ryan J. A., Sabaté-Gilarte M., Saxena A., Schumann D., Sedyshev P., Smith A. G., Sosnin N. V., Stamatopoulos A., Tagliente G., Tain J. L., Tarifeño-Saldivia A., Tassan-Got L., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vlastou R., Wallner A., Warren S., Weiss C., Woods P. J., Wright T., and Žugec P.
Subjects: Physics, QC1-999
Abstract: 233U is of key importance among the fissile nuclei in the Th-U fuel cycle. A particularity of 233U is its small neutron capture cross-section, which is on average about one order of magnitude lower than the fission cross-section. The accuracy in the measurement of the 233U capture cross-section depends crucially on an efficient capture-fission discrimination, thus a combined set-up of fission and γ-detectors is needed. A measurement of the 233U capture cross-section and capture-to-fission ratio was performed at the CERN n_TOF facility. The Total Absorption Calorimeter (TAC) of n_TOF was employed as γ-detector coupled with a novel compact ionization chamber as fission detector. A brief description of the experimental set-up will be given, and essential parts of the analysis procedure as well as the preliminary response of the set-up to capture are presented and discussed.
Published: 2019
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45. Measurement of the 244Cm and 246Cm neutron-induced capture cross sections at the n_TOF facility

Author: Alcayne V., Kimura A., Mendoza E., Cano-Ott D., Martínez T., Aberle O., Andrzejewski J., Audouin L., Bécares V., Bacak M., Barbagallo M., Becčvář F., Bellia G., Berthoumieux E., Billowes J., Bosnar D., Brown A., Busso M., Caamaño M., Caballero-Ontanaya L., Calviño F., Calviani M., Casanovas A., Cerutti F., Chen Y. H., Chiaveri E., Colonna N., Cortés G., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Diakaki M., Dietz M., Domingo-Pardo C., Dressler R., Dupont E., Durán I., Eleme Z., Fernández-Domínguez B., Ferrari A., Finocchiaro P., Furman V., Göbel K., Gawlik A., Gilardoni S., Glodariu T., Gonçalves I. F., González-Romero E., Guerrero C., Gunsing F., Harada H., Heinitz S., Heyse J., Jenkins D. G., Käppeler F., Kadi Y., Katabuchi T., Kivel N., Knapova I., Kokkoris M., Kopatch Y., Krtička M., Kurtulgil D., Ladarescu I., Lederer-Woods C., Lerendegui-Marco J., Meo S. Lo, Lonsdale S. J., Macina D., Manna A., Masi A., Massimi C., Mastinu P., Mastromarco M., Matteucci F., Maugeri E. A., Mazzone A., Mengoni A., Michalopoulou V., Milazzo P. M., Mingrone F., Musumarra A., Negret A., Nolte R., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Persanti L., Porras I., Praena J., Quesada J. M., Radeck D., Ramos-Doval D., Rauscher T., Reifarth R., Rochman D., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Simone S., Smith A. G., Sosnin N. V., Stamatopoulos A., Tagliente G., Tain J. L., Talip T., Tarifeño-Saldivia A., Tassan-Got L., Tsinganis A., Ulrich J., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T., and Žugec P.
Subjects: Physics, QC1-999
Abstract: The neutron capture reactions of the 244Cm and 246Cm isotopes open the path for the formation of heavier Cm isotopes and heavier elements such as Bk and Cf in a nuclear reactor. In addition, both isotopes belong to the minor actinides with a large contribution to the decay heat and to the neutron emission in irradiated fuels. There are only two previous 244Cm and 246Cm capture cross section measurements: one in 1969 using a nuclear explosion [1] and the most recent data measured at J-PARC in 2010 [2]. The data for both isotopes are very scarce due to the difficulties in performing the measurements: high intrinsic activity of the samples and limited facilities capable of providing isotopically enriched samples. We have measured both neutron capture cross sections at the n_TOF Experimental Area 2 (EAR-2) with three C6 D6 detectors and also at Area 1 (EAR-1) with the TAC. Preliminary results assessing the quality and limitations (back-ground subtraction, measurement technique and counting statistics) of this new experimental datasets are presented and discussed.
Published: 2019
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46. Fission program at n_TOF

Author: Tassan-Got L., Colonna N., Diakaki M., Eleme Z., Manna A., Sekhar A., Stamatopoulos A., Aberle O., Alcayne V., Amaducci S., Andrzejewski J., Audouin L., Babiano-Suarez V., Bacak M., Barbagallo M., Bennett S., Berthoumieux E., Bosnar D., Brown A. S., Busso M., Caamaño M., Caballero L., Calviani M., Calviño F., Cano-Ott D., Casanovas A., Cerutti F., Chiaveri E., Cortés G. P., Cortés-Giraldo M. A., Cosentino L., Cristallo S., Damone L. A., Davies P. J., Dietz M., Domingo-Pardo C., Dressler R., Ducasse Q., Dupont E., Durán I., Fernández-Domíngez B., Ferrari A., Ferro-Gonçalves I., Finocchiaro P., Furman V., Garg R., Gawlik A., Gilardoni S., Göbel K., González-Romero E., Guerrero C., Gunsing F., Heinitz S., Heyse J., Jenkins D. G., Jiri U., Junghans A., Kadi Y., Käppeler F., Kimura A., Knapová I., Kokkoris M., Kopatch Y., Krticˇka M., Kurtulgil D., Ladarescu I., Lederer-Woods C., Lerendegui-Marco J., Lonsdale S.-J., Macina D., Martínez T., Masi A., Massimi C., Mastinu P. F., Mastromarco M., Maugeri E., Mazzone A., Mendoza E., Mengoni A., Michalopoulou V., Milazzo P. M., Millán-Callado M. A., Mingrone F., Moreno-Soto J., Musumarra A., Negret A., Ogállar F., Oprea A., Patronis N., Pavlik A., Perkowski J., Petrone C., Piersanti L., Pirovano E., Porras I., Praena J., Quesada J. M., Ramos Doval D., Reifarth R., Rochman D., Rubbia C., Sabaté-Gilarte M., Saxena A., Schillebeeckx P., Schumann D., Smith A. G., Sosnin N., Sprung P., Tagliente G., Tain J. L., Tarifeño-Saldivia A. E., Thomas B., Torres-Sánchez P., Tsinganis A., Urlass S., Valenta S., Vannini G., Variale V., Vaz P., Ventura A., Vescovi D., Vlachoudis V., Vlastou R., Wallner A., Woods P. J., Wright T. J., and Žugec P.
Subjects: Physics, QC1-999
Abstract: Since its start in 2001 the n_TOF collaboration developed a measurement program on fission, in view of advanced fuels in new generation reactors. A special effort was made on measurement of cross sections of actinides, exploiting the peculiarity of the n_TOF neutron beam which spans a huge energy domain, from the thermal region up to GeV. Moreover fission fragment angular distributions have also been measured. An overview of the cross section results achieved with different detectors is presented, including a discussion of the 237Np case where discrepancies showed up between different detector systems. The results on the anisotropy of the fission fragments and its implication on the mechanism of neutron absorption, and in applications, are also shown.
Published: 2019
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47. Temporal changes in biomarker levels and their association with the early degeneration stage of transcatheter aortic valves in 18F-fluorodeoxyglucose and 18F-sodium fluoride positron emission tomography studies

Author: Danuta Sorysz, Artur Dziewierz, Katarzyna Gawlik, Marta Opalińska, Anna Sowa Staszczak, Anna Grochowska, Krzysztof Piotr Malinowski, Natalia Maruszak, Maciej Bagieński, and Dariusz Dudek
Subjects: biomarkers, lipoprotein a, metalloproteinases, osteopontin, osteoprotegerin, positron emission tomography, transcatheter aortic valve implantation, valve degeneration, valve durability, Medicine
Published: 2024
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48. A case of an 11-year-old boy with paediatric inflammatory multisystem syndrome associated with coronavirus disease, haemophagocytic lymphohistiocytosis, and systemic juvenile idiopathic arthritis

Author: Ewa Błaszczyk, Małgorzata Firek-Pędras, Elżbieta Berdej-Szczot, Agnieszka Mizia-Malarz, Anna Gruenpeter, Iwona Lachór-Motyka, Sabina Więcek, and Aneta Gawlik-Starzyk
Subjects: paediatric inflammatory multisystem syndrome associated with coronavirus disease, haemophagocytic lymphohistiocytosis, systemic juvenile idiopathic arthritis, covid-19, macrophage activation syndrome., Pediatrics, RJ1-570
Abstract: After the announcement of the coronavirus disease 2019 (COVID-19) pandemic, a new disease connected with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection was described: paediatric multisystem inflammatory syndrome associated with coronavirus disease (PIMS). PIMS is an acute and potentially dangerous inflammatory syndrome that may lead to cardiac complications. It requires differential diagnosis with Kawasaki disease. Some patients with PIMS can develop macrophage activation syndrome (MAS), which until now has occurred most commonly with systemic-onset juvenile idiopathic arthritis (JIA) and is closely related to haemophagocytic lymphohistiocytosis (HLH). In this article we present a case report of a patient with diagnosed PIMS, including PIMS with MAS, and with later diagnosis of HLH and JIA.
Published: 2024
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49. Thrombospondin-4 deletion does not exacerbate muscular dystrophy in β-sarcoglycan-deficient and laminin α2 chain-deficient mice

Author: Paula Zarén and Kinga I. Gawlik
Subjects: Medicine, Science
Abstract: Abstract Muscular dystrophy is a group of genetic disorders that lead to muscle wasting and loss of muscle function. Identifying genetic modifiers that alleviate symptoms or enhance the severity of a primary disease helps to understand mechanisms behind disease pathology and facilitates discovery of molecular targets for therapy. Several muscular dystrophies are caused by genetic defects in the components of the dystrophin-glycoprotein adhesion complex (DGC). Thrombospondin-4 overexpression has been shown to mitigate dystrophic disease in mouse models for Duchenne muscular dystrophy (dystrophin deficiency) and limb-girdle muscular dystrophy type 2F (LGMD2F, δ-sarcoglycan deficiency), while deletion of the thrombospondin-4 gene exacerbated the diseases. Hence, thrombospondin-4 has been considered a candidate molecule for therapy of muscular dystrophies involving the DGC. We have investigated whether thrombospondin-4 could act as a genetic modifier for other DGC-associated diseases: limb-girdle muscular dystrophy type 2E (LGMD2E, β-sarcoglycan deficiency) and laminin α2 chain-deficient muscular dystrophy (LAMA2-RD). Deletion of the thrombospondin-4 gene in mouse models for LGMD2E and LAMA2-RD, respectively, did not result in worsening of the dystrophic phenotype. Loss of thrombospondin-4 did not enhance sarcolemma damage and did not impair trafficking of transmembrane receptors integrin α7β1 and dystroglycan in double knockout muscles. Our results suggest that thrombospondin-4 might not be a relevant therapeutic target for all muscular dystrophies involving the DGC. This data also demonstrates that molecular pathology between very similar diseases like LGMD2E and 2F can differ significantly.
Published: 2024
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50. EU surveys insights: analytical tools, future directions, and the essential requirement for reference materials in wastewater monitoring of SARS-CoV-2, antimicrobial resistance and beyond

Author: Valentina Paracchini, Mauro Petrillo, Anandasagari Arcot Rajashekar, Piotr Robuch, Ursula Vincent, Philippe Corbisier, Simona Tavazzi, Barbara Raffael, Elisabetta Suffredini, Giuseppina La Rosa, Bernd Manfred Gawlik, and Antonio Marchini
Subjects: Public health, Wastewater surveillance, SARS-CoV-2, AMR, Analytical workflow, Standards, Medicine, Genetics, QH426-470
Abstract: Abstract Background Wastewater surveillance (WWS) acts as a vigilant sentinel system for communities, analysing sewage to protect public health by detecting outbreaks and monitoring trends in pathogens and contaminants. To achieve a thorough comprehension of present and upcoming practices and to identify challenges and opportunities for standardisation and improvement in WWS methodologies, two EU surveys were conducted targeting over 750 WWS laboratories across Europe and other regions. The first survey explored a diverse range of activities currently undertaken or planned by laboratories. The second survey specifically targeted methods and quality controls utilised for SARS-CoV-2 surveillance. Results The findings of the two surveys provide a comprehensive insight into the procedures and methodologies applied in WWS. In Europe, WWS primarily focuses on SARS-CoV-2 with 99% of the survey participants dedicated to this virus. However, the responses highlighted a lack of standardisation in the methodologies employed for monitoring SARS-CoV-2. The surveillance of other pathogens, including antimicrobial resistance, is currently fragmented and conducted by only a limited number of laboratories. Notably, these activities are anticipated to expand in the future. Survey replies emphasise the collective recognition of the need to enhance the accuracy of results in WWS practices, reflecting a shared commitment to advancing precision and effectiveness in WWS methodologies. Conclusions These surveys identified a lack of standardised common procedures in WWS practices and the need for quality standards and reference materials to enhance the accuracy and reliability of WWS methods in the future. In addition, it is important to broaden surveillance efforts beyond SARS-CoV-2 to include other emerging pathogens and antimicrobial resistance to ensure a comprehensive approach to protecting public health.
Published: 2024
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