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136 results on '"Gaub, M. P."'

6. Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult B-lineage ALL patients: the LALA 94 experience

Author

Picard, C, Hayette, S, Bilhou-Nabera, C, Cayuela, J M, Delabesse, E, Frenoy, N, Preudhomme, C, Dupont, M, Bastard, C, Bories, D, Vaerman, J L, Davi, F, Dastugue, N, Raynaud, S, Lafage, M, Deschaseaux, F, Fest, T, Gaub, M P, Lhéritier, V, Thomas, X, Charrin, C, Boucheix, C, Dombret, H, MacIntyre, E, Fière, D, and Gabert, J

Published
2006
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13. LIST OF CONTRIBUTORS AND DISCUSSANTS

Author

Anderson, R.N., primary, Aurbach, G.D., additional, Baird, A., additional, Balsan, S., additional, Bancroft, F.C., additional, Barofsky, A.L., additional, Barraclough, C.A., additional, Beattie, C.W., additional, Bellvé, A.R., additional, Billiar, R.B., additional, Bittman, E.L., additional, Bloch, B., additional, Böhlen, P., additional, Bradlow, H.L., additional, Brazeau, P., additional, Budzik, G.P., additional, Callard, G., additional, Callard, I., additional, Chambon, P., additional, Chatterton, R., additional, Clark, M.R., additional, Cohen, S.L., additional, Collins, D.C., additional, Concannon, P.W., additional, Cutler, G.B., additional, Czech, M.P., additional, DeGrange, D.A., additional, Dias, J.A., additional, Dierich, A., additional, Djiane, J., additional, Donahoe, P.K., additional, Drouin, J., additional, Dusanter-Fourt, I., additional, Earnest, D.J., additional, Eil, C., additional, Esch, F., additional, Feig, L., additional, Ferin, M., additional, Ferland, L.H., additional, Fiddes, J.C., additional, Foster, D.L., additional, French, F.S., additional, Friesen, H., additional, Frisch, R.E., additional, Gamblin, G.T., additional, Gaub, M-P., additional, Geller, J., additional, Gibori, G., additional, Goodman, R.L., additional, Grandison, L.J., additional, Greep, R.O., additional, Guillemin, R., additional, Gurr, J.A., additional, Hager, G.L., additional, Houdebine, L.-M., additional, Huseby, R.A., additional, Irvine, C., additional, Jakowlev, S., additional, Jongstra, J., additional, Kaibuchi, K., additional, Karsch, F.J., additional, Katoh, M., additional, Keefe, D.R., additional, Kelly, P.A., additional, Kessel, M., additional, Kikkawa, U., additional, Kishimoto, A., additional, Kourides, I.A., additional, Krust, A., additional, Labrie, F., additional, LePennec, J.-P., additional, Legan, S.J., additional, Liberman, U.A., additional, Lichtler, A.C., additional, Ling, N., additional, Littlefield, B.A., additional, MacDonald, G.J., additional, Marut, E.L., additional, Marx, S.J., additional, Means, A.R., additional, Merriam, G.R., additional, Moll, G., additional, Mougin, C., additional, Murphy, B., additional, Nekola, M.V., additional, Nicoll, C.S., additional, Nishizuka, Y., additional, Niswender, G.D., additional, Oppenheimer, J.H., additional, Osathanondh, R., additional, Ostrowski, M.C., additional, Oudet, P., additional, Papkoff, H., additional, Pastan, I., additional, Payne, A.H., additional, Pearson, O.H., additional, Peck, E.J., additional, Peter, R.E., additional, Pomerantz, D., additional, Posner, B., additional, Raj, M., additional, Rall, J.E., additional, Reudelhuber, T., additional, Richard-Foy, H., additional, Robertson, H., additional, Robinson, J.E., additional, Roser, J.F., additional, Russell, S.M., additional, Saffran, M., additional, Samaan, N., additional, Schulster, D., additional, Schwartz, N.B., additional, Segaloff, A., additional, Selmanoff, M.K., additional, Slaughter, G., additional, Sonnenschein, C., additional, Sterling, K., additional, Stone, R.T., additional, Swann, J., additional, Takai, Y., additional, Talmadge, K., additional, Teyssot, B., additional, Turek, F.W., additional, Van Vugt, D., additional, Walters, M.R., additional, Wardlaw, S., additional, Wehrenberg, W.B., additional, Weintraub, B., additional, Werder, K.V., additional, Wheeler, D., additional, Willingham, M.C., additional, Wise, P.M., additional, Wolf, O., additional, Wynn, P., additional, Ying, S.-Y., additional, Yoshinaga, Y., additional, Zeytin, F., additional, and Zor, U., additional

Published
1984
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14. ADENOVIRUS-2 MAJOR LATE PROMOTER : SEQUENCES UPSTREAM FROM THE TATA BOX ARE ESSENTIAL FOR EFFICIENT IN VIVO AND IN VITRO TRANSCRIPTION11This work was supported by grants from the CNRS (ATP 006520/50), from the INSERM (CRT 80.1029), from the “Association pour le Développement de la Recherche Française” and from the “Fondation Simone et Cino del Duca”.

Author

Sassone-Corsi, P., primary, Hen, R., additional, Corden, J., additional, Gaub, M.-P., additional, Chambon, P., additional, and Kédinger, C., additional

Published
1982
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15. Frequent intragenic rearrangements of DPYD in colorectal tumours

Author

van Kuilenburg, A B P, primary, Etienne-Grimaldi, M-C, additional, Mahamat, A, additional, Meijer, J, additional, Laurent-Puig, P, additional, Olschwang, S, additional, Gaub, M-P, additional, Hennekam, R C M, additional, Benchimol, D, additional, Houry, S, additional, Letoublon, C, additional, Gilly, F-N, additional, Pezet, D, additional, Andre, T, additional, Faucheron, J-L, additional, Abderrahim-Ferkoune, A, additional, Vijzelaar, R, additional, Pradere, B, additional, and Milano, G, additional

Published
2014
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16. TUMOUR BIOLOGY

Author

Geller, T., primary, Prakash, V., additional, Batanian, J., additional, Guzman, M., additional, Duncavage, E., additional, Gershon, T., additional, Crowther, A., additional, Wu, J., additional, Liu, H., additional, Fang, F., additional, Davis, I., additional, Tripolitsioti, D., additional, Ma, M., additional, Kumar, K., additional, Grahlert, J., additional, Egli, K., additional, Fiaschetti, G., additional, Shalaby, T., additional, Grotzer, M., additional, Baumgartner, M., additional, Braoudaki, M., additional, Lambrou, G. I., additional, Giannikou, K., additional, Millionis, V., additional, Papadodima, S. A., additional, Settas, N., additional, Sfakianos, G., additional, Stefanaki, K., additional, Kattamis, A., additional, Spiliopoulou, C. A., additional, Tzortzatou-Stathopoulou, F., additional, Kanavakis, E., additional, Gholamin, S., additional, Mitra, S., additional, Feroze, A., additional, Zhang, M., additional, Esparza, R., additional, Kahn, S., additional, Richard, C., additional, Achrol, A., additional, Volkmer, A., additional, Liu, J., additional, Volkmer, J., additional, Majeti, R., additional, Weissman, I., additional, Cheshier, S., additional, Bhatia, K., additional, Brown, N., additional, Teague, J., additional, Lo, P., additional, Challis, J., additional, Beshay, V., additional, Sullivan, M., additional, Mechinaud, F., additional, Hansford, J., additional, Arifin, M. Z., additional, Dahlan, R. H., additional, Sobana, M., additional, Saputra, P., additional, Tisell, M. T., additional, Danielsson, A., additional, Caren, H., additional, Bhardwaj, R., additional, Chakravadhanula, M., additional, Hampton, C., additional, Ozals, V., additional, Georges, J., additional, Decker, W., additional, Kodibagkar, V., additional, Nguyen, A., additional, Legrain, M., additional, Gaub, M. P., additional, Pencreach, E., additional, Chenard, M. P., additional, Guenot, D., additional, Entz-Werle, N., additional, Kanemura, Y., additional, Ichimura, K., additional, Shofuda, T., additional, Nishikawa, R., additional, Yamasaki, M., additional, Shibui, S., additional, Arai, H., additional, Xia, J., additional, Brian, A., additional, Prins, R., additional, Pennell, C., additional, Moertel, C., additional, Olin, M., additional, Bie, L., additional, Zhang, X., additional, Olsson, M., additional, Kling, T., additional, Nelander, S., additional, Biassoni, V., additional, Bongarzone, I., additional, Verderio, P., additional, Massimino, M., additional, Magni, R., additional, Pizzamiglio, S., additional, Ciniselli, C., additional, Taverna, E., additional, De Bortoli, M., additional, Luchini, A., additional, Liotta, L., additional, Barzano, E., additional, Spreafico, F., additional, Visse, E., additional, Sanden, E., additional, Darabi, A., additional, Siesjo, P., additional, Jackson, S., additional, Cohen, K., additional, Lin, D., additional, Burger, P., additional, Rodriguez, F., additional, Yao, X., additional, Liucheng, R., additional, Qin, L., additional, Na, T., additional, Meilin, W., additional, Zhengdong, Z., additional, Yongjun, F., additional, Pfeifer, S., additional, Nister, M., additional, de Stahl, T. D., additional, Basmaci, E., additional, Orphanidou-Vlachou, E., additional, Brundler, M.-A., additional, Sun, Y., additional, Davies, N., additional, Wilson, M., additional, Pan, X., additional, Arvanitis, T., additional, Grundy, R., additional, Peet, A., additional, Eden, C., additional, Ju, B., additional, Phoenix, T., additional, Nimmervoll, B., additional, Tong, Y., additional, Ellison, D., additional, Lessman, C., additional, Taylor, M., additional, Gilbertson, R., additional, Folgiero, V., additional, del Bufalo, F., additional, Carai, A., additional, Cefalo, M. G., additional, Citti, A., additional, Rutella, S., additional, Locatelli, F., additional, Mastronuzzi, A., additional, Maher, O., additional, Khatua, S., additional, Zaky, W., additional, Lourdusamy, A., additional, Meijer, L., additional, Layfield, R., additional, Jones, D. T. W., additional, Capper, D., additional, Sill, M., additional, Hovestadt, V., additional, Schweizer, L., additional, Lichter, P., additional, Zagzag, D., additional, Karajannis, M. A., additional, Aldape, K. D., additional, Korshunov, A., additional, von Deimling, A., additional, Pfister, S., additional, Chakrabarty, A., additional, Feltbower, R., additional, Sheridon, E., additional, Hassan, H., additional, Shires, M., additional, Picton, S., additional, Hatziagapiou, K., additional, Tsorteki, F., additional, Bethanis, K., additional, Gemou-Engesaeth, V., additional, Chi, S. N., additional, Bandopadhayay, P., additional, Janeway, K., additional, Pinches, N., additional, Malkin, H., additional, Kieran, M. W., additional, Manley, P. E., additional, Green, A., additional, Goumnerova, L., additional, Ramkissoon, S., additional, Harris, M. H., additional, Ligon, K. L., additional, Kahlert, U., additional, Suarez, M., additional, Maciaczyk, J., additional, Bar, E., additional, Eberhart, C., additional, Kenchappa, R., additional, Krishnan, N., additional, Forsyth, P., additional, McKenzie, B., additional, Pisklakova, A., additional, McFadden, G., additional, Pan, W., additional, Rodriguez, L., additional, Glod, J., additional, Levy, J. M., additional, Thompson, J., additional, Griesinger, A., additional, Amani, V., additional, Donson, A., additional, Birks, D., additional, Morgan, M., additional, Handler, M., additional, Foreman, N., additional, Thorburn, A., additional, Lulla, R. R., additional, Laskowski, J., additional, Fangusaro, J., additional, DiPatri, A. J., additional, Alden, T., additional, Tomita, T., additional, Vanin, E. F., additional, Goldman, S., additional, Soares, M. B., additional, Remke, M., additional, Ramaswamy, V., additional, Wang, X., additional, Jorgensen, F., additional, Morrissy, A. S., additional, Marra, M., additional, Packer, R., additional, Bouffet, E., additional, Jabado, N., additional, Cole, B., additional, Rudzinski, E., additional, Anderson, M., additional, Bloom, K., additional, Lee, A., additional, Leary, S., additional, Leprivier, G., additional, Rotblat, B., additional, Agnihotri, S., additional, Kool, M., additional, Derry, B., additional, Taylor, M. D., additional, Sorensen, P. H., additional, Dobson, T., additional, Busschers, E., additional, Taylor, H., additional, Hatcher, R., additional, Lulla, R., additional, Rajaram, V., additional, Das, C., additional, and Gopalakrishnan, V., additional

Published
2014
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17. HIGH GRADE GLIOMAS AND DIPG

Author

Classen, C. F., primary, William, D., additional, Linnebacher, M., additional, Farhod, A., additional, Kedr, W., additional, Elsabe, B., additional, Fadel, S., additional, Van Gool, S., additional, De Vleeschouwer, S., additional, Koks, C., additional, Garg, A., additional, Ehrhardt, M., additional, Riva, M., additional, Agostinis, P., additional, Graf, N., additional, Yao, T.-W., additional, Yoshida, Y., additional, Zhang, J., additional, Ozawa, T., additional, James, D., additional, Nicolaides, T., additional, Kebudi, R., additional, Cakir, F. B., additional, Gorgun, O., additional, Agaoglu, F. Y., additional, Darendeliler, E., additional, Al-Kofide, A., additional, Al-Shail, E., additional, Khafaga, Y., additional, Al-Hindi, H., additional, Dababo, M., additional, Haq, A. U., additional, Anas, M., additional, Barria, M. G., additional, Siddiqui, K., additional, Hassounah, M., additional, Ayas, M., additional, van Zanten, S. V., additional, Jansen, M., additional, van Vuurden, D., additional, Huisman, M., additional, Vugts, D., additional, Hoekstra, O., additional, van Dongen, G., additional, Kaspers, G., additional, Cockle, J., additional, Ilett, E., additional, Scott, K., additional, Bruning-Richardson, A., additional, Picton, S., additional, Short, S., additional, Melcher, A., additional, Benesch, M., additional, Warmuth-Metz, M., additional, von Bueren, A. O., additional, Hoffmann, M., additional, Pietsch, T., additional, Kortmann, R.-D., additional, Eyrich, M., additional, Rutkowski, S., additional, Fruhwald, M. C., additional, Faber, J., additional, Kramm, C., additional, Porkholm, M., additional, Valanne, L., additional, Lonnqvist, T., additional, Holm, S., additional, Lannering, B., additional, Riikonen, P., additional, Wojcik, D., additional, Sehested, A., additional, Clausen, N., additional, Harila-Saari, A., additional, Schomerus, E., additional, Thorarinsdottir, H. K., additional, Lahteenmaki, P., additional, Arola, M., additional, Thomassen, H., additional, Saarinen-Pihkala, U. M., additional, Kivivuori, S.-M., additional, Buczkowicz, P., additional, Hoeman, C., additional, Rakopoulos, P., additional, Pajovic, S., additional, Morrison, A., additional, Bouffet, E., additional, Bartels, U., additional, Becher, O., additional, Hawkins, C., additional, Gould, T. W. A., additional, Rahman, C. V., additional, Smith, S. J., additional, Barrett, D. A., additional, Shakesheff, K. M., additional, Grundy, R. G., additional, Rahman, R., additional, Barua, N., additional, Cronin, D., additional, Gill, S., additional, Lowisl, S., additional, Hochart, A., additional, Maurage, C.-A., additional, Rocourt, N., additional, Vinchon, M., additional, Kerdraon, O., additional, Escande, F., additional, Grill, J., additional, Pick, V. K., additional, Leblond, P., additional, Burzynski, G., additional, Janicki, T., additional, Burzynski, S., additional, Marszalek, A., additional, Ramani, N., additional, Zaky, W., additional, Kannan, G., additional, Morani, A., additional, Sandberg, D., additional, Ketonen, L., additional, Maher, O., additional, Corrales-Medina, F., additional, Meador, H., additional, Khatua, S., additional, Brassesco, M., additional, Delsin, L., additional, Roberto, G., additional, Silva, C., additional, Ana, L., additional, Rego, E., additional, Scrideli, C., additional, Umezawa, K., additional, Tone, L., additional, Kim, S. J., additional, Kim, C.-Y., additional, Kim, I.-A., additional, Han, J. H., additional, Choi, B.-S., additional, Ahn, H. S., additional, Choi, H. S., additional, Haque, F., additional, Layfield, R., additional, Grundy, R., additional, Gandola, L., additional, Pecori, E., additional, Biassoni, V., additional, Schiavello, E., additional, Chiruzzi, C., additional, Spreafico, F., additional, Modena, P., additional, Bach, F., additional, Pignoli, E., additional, Massimino, M., additional, Drogosiewicz, M., additional, Dembowska-Baginska, B., additional, Jurkiewicz, E., additional, Filipek, I., additional, Perek-Polnik, M., additional, Swieszkowska, E., additional, Perek, D., additional, Bender, S., additional, Jones, D. T., additional, Warnatz, H.-J., additional, Hutter, B., additional, Zichner, T., additional, Gronych, J., additional, Korshunov, A., additional, Eils, R., additional, Korbel, J. O., additional, Yaspo, M.-L., additional, Lichter, P., additional, Pfister, S. M., additional, Yadavilli, S., additional, Becher, O. J., additional, Kambhampati, M., additional, Packer, R. J., additional, Nazarian, J., additional, Lechon, F. C., additional, Fowkes, L., additional, Khabra, K., additional, Martin-Retortillo, L. M., additional, Marshall, L. V., additional, Vaidya, S., additional, Koh, D.-M., additional, Leach, M. O., additional, Pearson, A. D., additional, Zacharoulis, S., additional, Schrey, D., additional, Barone, G., additional, Panditharatna, E., additional, Stampar, M., additional, Siu, A., additional, Gordish-Dressman, H., additional, Devaney, J., additional, Hwang, E. I., additional, Chung, A. H., additional, Mittapalli, R. K., additional, Elmquist, W. F., additional, Castel, D., additional, Debily, M.-A., additional, Philippe, C., additional, Truffaux, N., additional, Taylor, K., additional, Calmon, R., additional, Boddaert, N., additional, Le Dret, L., additional, Saulnier, P., additional, Lacroix, L., additional, Mackay, A., additional, Jones, C., additional, Puget, S., additional, Sainte-Rose, C., additional, Blauwblomme, T., additional, Varlet, P., additional, Entz-Werle, N., additional, Maugard, C., additional, Bougeard, G., additional, Nguyen, A., additional, Chenard, M. P., additional, Schneider, A., additional, Gaub, M. P., additional, Tsoli, M., additional, Vanniasinghe, A., additional, Luk, P., additional, Dilda, P., additional, Haber, M., additional, Hogg, P., additional, Ziegler, D., additional, Simon, S., additional, Monje, M., additional, Gurova, K., additional, Gudkov, A., additional, Zapotocky, M., additional, Churackova, M., additional, Malinova, B., additional, Zamecnik, J., additional, Kyncl, M., additional, Tichy, M., additional, Puchmajerova, A., additional, Stary, J., additional, Sumerauer, D., additional, Boult, J., additional, Vinci, M., additional, Perryman, L., additional, Box, G., additional, Jury, A., additional, Popov, S., additional, Ingram, W., additional, Eccles, S., additional, Robinson, S., additional, Emir, S., additional, Demir, H. A., additional, Bayram, C., additional, Cetindag, F., additional, Kabacam, G. B., additional, Fettah, A., additional, Li, J., additional, Jamin, Y., additional, Cummings, C., additional, Bamber, J., additional, Sinkus, R., additional, Nandhabalan, M., additional, Bjerke, L., additional, Burford, A., additional, von Bueren, A., additional, Baudis, M., additional, Clarke, P., additional, Collins, I., additional, Workman, P., additional, Olaciregui, N., additional, Mora, J., additional, Carcaboso, A., additional, Bullock, A., additional, Alonso, M., additional, de Torres, C., additional, Cruz, O., additional, Pencreach, E., additional, Moussalieh, F. M., additional, Guenot, D., additional, Namer, I., additional, Pollack, I., additional, Jakacki, R., additional, Butterfield, L., additional, Hamilton, R., additional, Panigrahy, A., additional, Potter, D., additional, Connelly, A., additional, Dibridge, S., additional, Whiteside, T., additional, Okada, H., additional, Ahsan, S., additional, Raabe, E., additional, Haffner, M., additional, Warren, K., additional, Quezado, M., additional, Ballester, L., additional, Eberhart, C., additional, Rodriguez, F., additional, Ramachandran, C., additional, Nair, S., additional, Quirrin, K.-W., additional, Khatib, Z., additional, Escalon, E., additional, Melnick, S., additional, Classen, C. F., additional, Hofmann, M., additional, Schmid, I., additional, Simon, T., additional, Maass, E., additional, Russo, A., additional, Fleischhack, G., additional, Becker, M., additional, Hauch, H., additional, Sander, A., additional, Grasso, C., additional, Berlow, N., additional, Liu, L., additional, Davis, L., additional, Huang, E., additional, Woo, P., additional, Tang, Y., additional, Ponnuswami, A., additional, Chen, S., additional, Huang, Y., additional, Hutt-Cabezas, M., additional, Dret, L., additional, Meltzer, P., additional, Mao, H., additional, Abraham, J., additional, Fouladi, M., additional, Svalina, M. N., additional, Wang, N., additional, Hulleman, E., additional, Li, X.-N., additional, Keller, C., additional, Spellman, P. T., additional, Pal, R., additional, Jansen, M. H. A., additional, Sewing, A. C. P., additional, Lagerweij, T., additional, Vuchts, D. J., additional, van Vuurden, D. G., additional, Caretti, V., additional, Wesseling, P., additional, Kaspers, G. J. L., additional, Cohen, K., additional, Pearl, M., additional, Kogiso, M., additional, Zhang, L., additional, Qi, L., additional, Lindsay, H., additional, Lin, F., additional, Berg, S., additional, Muscal, J., additional, Amayiri, N., additional, Tabori, U., additional, Campbel, B., additional, Bakry, D., additional, Aronson, M., additional, Durno, C., additional, Gallinger, S., additional, Malkin, D., additional, Qaddumi, I., additional, Musharbash, A., additional, Swaidan, M., additional, Al-Hussaini, M., additional, Shandilya, S., additional, McCully, C., additional, Murphy, R., additional, Akshintala, S., additional, Cole, D., additional, Macallister, R. P., additional, Cruz, R., additional, Widemann, B., additional, Salloum, R., additional, Smith, A., additional, Glaunert, M., additional, Ramkissoon, A., additional, Peterson, S., additional, Baker, S., additional, Chow, L., additional, Sandgren, J., additional, Pfeifer, S., additional, Popova, S., additional, Alafuzoff, I., additional, de Stahl, T. D., additional, Pietschmann, S., additional, Kerber, M. J., additional, Zwiener, I., additional, Henke, G., additional, Muller, K., additional, Sieow, N. Y.-F., additional, Hoe, R. H. M., additional, Tan, A. M., additional, Chan, M. Y., additional, Soh, S. Y., additional, Burrell, K., additional, Chornenkyy, Y., additional, Remke, M., additional, Golbourn, B., additional, Barzczyk, M., additional, Taylor, M., additional, Rutka, J., additional, Dirks, P., additional, Zadeh, G., additional, Agnihotri, S., additional, Hashizume, R., additional, Ihara, Y., additional, Andor, N., additional, Chen, X., additional, Lerner, R., additional, Huang, X., additional, Tom, M., additional, Solomon, D., additional, Mueller, S., additional, Petritsch, C., additional, Zhang, Z., additional, Gupta, N., additional, Waldman, T., additional, Dujua, A., additional, Co, J., additional, Hernandez, F., additional, Doromal, D., additional, Hegde, M., additional, Wakefield, A., additional, Brawley, V., additional, Grada, Z., additional, Byrd, T., additional, Chow, K., additional, Krebs, S., additional, Heslop, H., additional, Gottschalk, S., additional, Yvon, E., additional, Ahmed, N., additional, Cornilleau, G., additional, Paulsson, J., additional, Andreiuolo, F., additional, Guerrini-Rousseau, L., additional, Geoerger, B., additional, Vassal, G., additional, Ostman, A., additional, Parsons, D. W., additional, Trevino, L. R., additional, Gao, F., additional, Shen, X., additional, Hampton, O., additional, Kosigo, M., additional, Baxter, P. A., additional, Su, J. M., additional, Chintagumpala, M., additional, Dauser, R., additional, Adesina, A., additional, Plon, S. E., additional, Wheeler, D. A., additional, Lau, C. C., additional, Gielen, G., additional, Muehlen, A. z., additional, Kwiecien, R., additional, Wolff, J., additional, Lulla, R. R., additional, Laskowski, J., additional, Goldman, S., additional, Gopalakrishnan, V., additional, Fangusaro, J., additional, Kieran, M., additional, Fontebasso, A., additional, Papillon-Cavanagh, S., additional, Schwartzentruber, J., additional, Nikbakht, H., additional, Gerges, N., additional, Fiset, P.-O., additional, Bechet, D., additional, Faury, D., additional, De Jay, N., additional, Ramkissoon, L., additional, Corcoran, A., additional, Jones, D., additional, Sturm, D., additional, Johann, P., additional, Tomita, T., additional, Nagib, M., additional, Bendel, A., additional, Goumnerova, L., additional, Bowers, D. C., additional, Leonard, J. R., additional, Rubin, J. B., additional, Alden, T., additional, DiPatri, A., additional, Browd, S., additional, Leary, S., additional, Jallo, G., additional, Prados, M. D., additional, Banerjee, A., additional, Carret, A.-S., additional, Ellezam, B., additional, Crevier, L., additional, Klekner, A., additional, Bognar, L., additional, Hauser, P., additional, Garami, M., additional, Myseros, J., additional, Dong, Z., additional, Siegel, P. M., additional, Gump, W., additional, Ayyanar, K., additional, Ragheb, J., additional, Krieger, M., additional, Kiehna, E., additional, Robison, N., additional, Harter, D., additional, Gardner, S., additional, Handler, M., additional, Foreman, N., additional, Brahma, B., additional, MacDonald, T., additional, Malkin, H., additional, Chi, S., additional, Manley, P., additional, Bandopadhayay, P., additional, Greenspan, L., additional, Ligon, A., additional, Albrecht, S., additional, Ligon, K. L., additional, Majewski, J., additional, Jabado, N., additional, Cordero, F., additional, Halvorson, K., additional, Taylor, I., additional, Hutt, M., additional, Weingart, M., additional, Price, A., additional, Kantar, M., additional, Onen, S., additional, Kamer, S., additional, Turhan, T., additional, Kitis, O., additional, Ertan, Y., additional, Cetingul, N., additional, Anacak, Y., additional, Akalin, T., additional, Ersahin, Y., additional, Mason, G., additional, Ho, C., additional, Crozier, F., additional, Vezina, G., additional, Packer, R., additional, Hwang, E., additional, Gilheeney, S., additional, Millard, N., additional, DeBraganca, K., additional, Khakoo, Y., additional, Kramer, K., additional, Wolden, S., additional, Donzelli, M., additional, Fischer, C., additional, Petriccione, M., additional, Dunkel, I., additional, Afzal, S., additional, Fleming, A., additional, Larouche, V., additional, Zelcer, S., additional, Johnston, D. L., additional, Kostova, M., additional, Mpofu, C., additional, Decarie, J.-C., additional, Strother, D., additional, Lafay-Cousin, L., additional, Eisenstat, D., additional, Fryer, C., additional, Hukin, J., additional, Hsu, M., additional, Lasky, J., additional, Moore, T., additional, Liau, L., additional, Davidson, T., additional, Prins, R., additional, Hassal, T., additional, Baugh, J., additional, Kirkendall, J., additional, Doughman, R., additional, Leach, J., additional, Jones, B., additional, Miles, L., additional, Hargrave, D., additional, Jacques, T., additional, Savage, S., additional, Saunders, D., additional, Wallace, R., additional, Flutter, B., additional, Morgenestern, D., additional, Blanco, E., additional, Howe, K., additional, Lowdell, M., additional, Samuel, E., additional, Michalski, A., additional, Anderson, J., additional, Arakawa, Y., additional, Umeda, K., additional, Watanabe, K.-i., additional, Mizowaki, T., additional, Hiraoka, M., additional, Hiramatsu, H., additional, Adachi, S., additional, Kunieda, T., additional, Takagi, Y., additional, Miyamoto, S., additional, Venneti, S., additional, Santi, M., additional, Felicella, M. M., additional, Sullivan, L. M., additional, Dolgalev, I., additional, Martinez, D., additional, Perry, A., additional, Lewis, P. W., additional, Allis, D. C., additional, Thompson, C. B., additional, and Judkins, A. R., additional

Published
2014
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18. Molecular patterns in deficient mismatch repair colorectal tumours: results from a French prospective multicentric biological and genetic study

Author

Etienne-Grimaldi, M-C, primary, Mahamat, A, additional, Chazal, M, additional, Laurent-Puig, P, additional, Olschwang, S, additional, Gaub, M-P, additional, Formento, J-L, additional, Formento, P, additional, Sudaka, A, additional, Boige, V, additional, Abderrahim-Ferkoune, A, additional, Benchimol, D, additional, André, T, additional, Houry, S, additional, Faucheron, J-L, additional, Letoublon, C, additional, Gilly, F-N, additional, Delpero, J-R, additional, Lasser, P, additional, Pradere, B, additional, Pezet, D, additional, Penault-Llorca, F, additional, and Milano, G, additional

Published
2014
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20. Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers

Author

Svrcek, M., primary, Buhard, O., additional, Colas, C., additional, Coulet, F., additional, Dumont, S., additional, Massaoudi, I., additional, Lamri, A., additional, Hamelin, R., additional, Cosnes, J., additional, Oliveira, C., additional, Seruca, R., additional, Gaub, M.-P., additional, Legrain, M., additional, Collura, A., additional, Lascols, O., additional, Tiret, E., additional, Flejou, J.-F., additional, and Duval, A., additional

Published
2010
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23. Genetic alterations in primary osteosarcoma from 54 children and adolescents by targeted allelotyping

Author

Entz-Werle, N, primary, Schneider, A, additional, Kalifa, C, additional, Voegeli, A-C, additional, Tabone, M-D, additional, Marec-Berard, P, additional, Marcellin, L, additional, Pacquement, H, additional, Terrier, P, additional, Boutard, P, additional, Meyer, N, additional, Gaub, M-P, additional, Lutz, P, additional, Babin, A, additional, and Oudet, P, additional

Published
2003
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24. Distinct conformations of vitamin D receptor/retinoid X receptor-alpha heterodimers are specified by dinucleotide differences in the vitamin D-responsive elements of the osteocalcin and osteopontin genes.

Author

Staal, A, primary, van Wijnen, A J, additional, Birkenhäger, J C, additional, Pols, H A, additional, Prahl, J, additional, DeLuca, H, additional, Gaub, M P, additional, Lian, J B, additional, Stein, G S, additional, van Leeuwen, J P, additional, and Stein, J L, additional

Published
1996
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33. Van Hove Function for Diffusion in Zeolites

Author

Gaub, M., Fritzsche, S., Haberlandt, R., and Theodorou, D. N.

Abstract

An approximation for the self-part of the van Hove function is derived. The self-part of the van Hove function is calculated by MD simulation for the diffusion of methane in ZK4 and silicalite and compared with the approximation. Fourier transform in space of the van Hove function yields the intermediate scattering function, the decay of which is used to determine the self-diffusion coefficient. Fourier transform in time yields the dynamic structure factor which can be compared with quasi-elastic neutron scattering results.

Published
1999

34. Cell‐specific activity of a GGTCA half‐palindromic oestrogen‐responsive element in the chicken ovalbumin gene promoter.

Author

Tora, L., Gaub, M. P., Mader, S., Dierich, A., Bellard, M., and Chambon, P.

Abstract

Using a transient co‐transfection system we have identified a functional oestrogen responsive element (ERE) in the near vicinity of the TATA box of the chicken ovalbumin gene promoter. Oestrogen induced activation of transcription was observed only in chicken embryo fibroblast cells, and not in human HeLa cells, suggesting the existence of a cell‐specific transcription factor(s) that is necessary for the hormonal response. By 5′‐deletion mapping and site‐directed mutagenesis, a sequence encompassing the more proximal of two GGTCA half‐palindromic motifs was identified as a functional ovalbumin gene ERE. Both motifs correspond to oestrogen receptor binding sites in vitro as revealed by DNase I footprinting. Optimal response to the hormonal stimulus apparently requires stereoalignment of the ERE and the TATA box.

Published
1988
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35. Cell‐specificity of the chicken ovalbumin and conalbumin promoters.

Author

Dierich, A., Gaub, M. P., LePennec, J. P., Astinotti, D., and Chambon, P.

Abstract

A series of recombinant plasmids containing increasing lengths of the 5′‐flanking promoter sequences of the chicken conalbumin and ovalbumin genes fused to the sequences coding for the SV40 T‐antigen have been constructed. These recombinants were introduced into a variety of established cell lines and primary cultured cells by nuclear microinjection. Promoter activity was estimated by monitoring T‐antigen synthesis by indirect immunofluorescence. We show that the microinjected ovalbumin and conalbumin promoter regions do not function in chicken fibroblasts, kidney cells and in a variety of non‐chicken cells, irrespective of the presence of steroid hormone receptors. In contrast, these promoter regions are active in primary cultured chicken embryonic hepatocytes and oviduct tubular gland cells, suggesting the presence of cell‐specific transcription factors in these cells. Unexpectedly, promoter sequences close to the TATA boxes of both the ovalbumin and conalbumin genes are sufficient to confer cell‐specific expression. Most of the controls exerted on the ovalbumin and conalbumin promoters in the whole animal appear to be reproduced in vitro by nuclear microinjection of the chimeric genes into the primary cultured cells. However, the microinjected ovalbumin promoter is active in embryonic hepatocytes and thus escapes the regulation imposed on the corresponding inactive endogenous gene.

Published
1987
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36. The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones.

Author

Gaub, M. P., Dierich, A., Astinotti, D., Touitou, I., and Chambon, P.

Abstract

Steroid hormone regulation of activity of the chicken ovalbumin promoter was studied by microinjection of chimeric genes into the nuclei of primary cultured oviduct tubular gland cells. The chimeric genes contained increasing lengths of ovalbumin gene 5′‐flanking sequences fused to the sequence coding for the SV40 T‐antigen. Promoter activity was estimated by monitoring synthesis of T‐antigen. The activity of the ovalbumin promoter is cell‐specifically repressed in these oviduct cells and the repression is relieved upon addition of steroid hormones. The −132 to −425 region of the ovalbumin promoter which is responsible for this negative regulation behaves as an independent functional unit containing the regulatory elements necessary for both repression (in the presence of steroid hormone antagonists) and induced derepression (in the presence of steroid hormones) of linked heterologous promoters.

Published
1987
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37. Antibodies specific to the retinoic acid human nuclear receptors alpha and beta.

Author

Gaub, M P, Lutz, Y, Ruberte, E, Petkovich, M, Brand, N, and Chambon, P

Abstract

Two cDNAs encoding two human receptors for retinoic acid (RA), RAR-alpha and RAR-beta, have been characterized recently. Synthetic peptides corresponding to the cDNA-deduced amino acid sequences unique to RAR-alpha and RAR-beta were used to generate anti-RAR-alpha antiserum (SP171) and anti-RAR-beta antisera (SP172 and SP248). The specificity of these antisera was confirmed both by immunocytochemical detection of these receptors in COS-1 cells transfected with RAR-alpha and RAR-beta expression vectors and by immunoblot analyses performed with whole extracts of these cells. We also demonstrate that these antisera recognize RAR-alpha and RAR-beta endogenously expressed in the RA-responsive human promyelocytic leukemia cell line HL-60.

Published
1989
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38. Protein phosphatases 1 and 2A regulate the transcriptional and DNA binding activities of retinoic acid receptors.

Author

Lefebvre, P, Gaub, M P, Tahayato, A, Rochette-Egly, C, and Formstecher, P

Abstract

To determine which factors may regulate the DNA binding and transcriptional properties of retinoic acid receptors (RARs and RXRs), we investigated the sensitivity of reporter genes bearing various retinoic acid response elements (RAREs) to protein phosphatases (PPases) inhibition. PPases inhibition by okadaic acid led to an increase of the reporter genes activity in a RARE-dependent and ligand-independent manner and was dependent on the type of response element used. Overexpression of protein phosphatases 2A and 1 (PP2A and PP1) decreased the inducibility of the reporter genes tested. Nuclear extracts from okadaic acid-treated COS cells displayed an 2-5-fold increased level of receptor binding to RAREs in vitro, suggesting that PPases inhibition increased the DNA binding activity of retinoid receptors. Treatment of receptors extracted from COS cells by alkaline phosphatase and partially purified PP1 and PP2A decreased their DNA binding activity, but heterodimers bound to DNA were not sensitive to phosphatase treatment. Reconstitution experiments showed that phosphorylation of both receptors increased the DNA binding activity of RXR/RAR heterodimers. Taken together, these data show that the modulation of the phosphorylation state of RARs and RXRs represents an other level of regulation of the retinoid signaling pathway.

Published
1995

42. Emergence Trap and Holding Bottle for the Capture of Salmonid Fry in Streams

Author

Fraley, J. J., Gaub, M. A., and Cavigli, J. R.

Abstract

A 0.12-m 2 fry emergence trap was constructed of rigid steel strip, plumber's tape, and nylon netting. A holding bottle was fashioned from a polyethylene screw cap bottle and plastic funnel. The trap was inexpensive, durable, and effective in a wide range of current velocities. The method proved effective in estimating egg-to-fry survival rates for kokanee (Oncorhynchus nerka) in various sediment mixtures. Egg-to-fry survival varied from 0 to 52%, and was negatively correlated to percent fines (r = 0.91; P < 0.01). The emergence period indicated by the trap catches in McDonald Creek agreed closely with the period indicated by drift-net sampling. Fry mortality in the holding bottle was almost nil if the trap was checked at least once a week.

Published
1986
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44. Molecular analysis of urine sediment for follow-up of urinary tract cancers.

Author

Chiang, P W, Schneider, A, Borgnat, S, Gaub, M P, Oudet, P, Kurnit, D M, and Jacqmin, D

Subjects
CANCER, COMPARATIVE studies, CYSTOSCOPY, DNA, RESEARCH methodology, MEDICAL cooperation, POLYMERASE chain reaction, RESEARCH, URINARY organs, URINE, EVALUATION research, CASE-control method
Published
2000

47. EGFR-TKI and lung adenocarcinoma with CNS relapse: interest of molecular follow-up.

Author

Ruppert AM, Beau-Faller M, Neuville A, Guerin E, Voegeli AC, Mennecier B, Legrain M, Molard A, Jeung MY, Gaub MP, Oudet P, and Quoix E

Subjects
Adult, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Drug Resistance, Neoplasm, Erlotinib Hydrochloride, Gefitinib, Humans, Liver Neoplasms secondary, Liver Neoplasms therapy, Male, Neoplasm Metastasis, Quinazolines administration & dosage, Recurrence, Treatment Outcome, Adenocarcinoma pathology, Adenocarcinoma therapy, Central Nervous System Neoplasms secondary, Central Nervous System Neoplasms therapy, ErbB Receptors antagonists & inhibitors, ErbB Receptors metabolism, Lung Neoplasms pathology, Lung Neoplasms therapy
Abstract

The epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) erlotinib improves survival of lung cancer as second- or third-line therapy. However, after an initial response, most patients will recur, particularly within the central nervous system. The present study reports the case of a 27-yr-old nonsmoking male presenting with a metastatic lung adenocarcinoma with EGFR exon 19 deletion, associated with sensitivity to EGFR-TKI. Gefitinib, followed by chemotherapy and finally erlotinib resulted in prolonged disease control, until multiple liver metastases were detected. After stopping EGFR-TKI, brain metastases with carcinomatous meningitis were diagnosed. A secondary T790M mutation, associated with resistance to EGFR-TKI, was found on the liver biopsy but not in the cerebrospinal fluid. Erlotinib was reintroduced and allowed a quick neurological improvement, even though the extra-cranial disease remained resistant to erlotinib. The present report underscores the interest of molecular monitoring in lung cancer. Persistent cerebral tyrosine kinase inhibitor sensitivity should be considered in patients presenting with an early central nervous system relapse after stopping epidermal growth factor receptor tyrosine kinase inhibitor, even with a T790M-resistant mutation in noncerebral metastases. Questions remain concerning the selection of sub-clones during epidermal growth factor receptor tyrosine kinase inhibitor therapy, which could differ according to metastatic sites, especially in the central nervous system.

Published
2009
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48. Allelic imbalance at loci containing FGFR, FGF, c-Met and HGF candidate genes in non-small cell lung cancer sub-types, implication for progression.

Author

Beau-Faller M, Gaub MP, Schneider A, Guérin E, Meyer N, Ducrocq X, Massard G, Gasser B, Kessler R, Weitzenblum E, Wihlm JM, Quoix E, and Oudet P

Subjects
Adult, Aged, Aged, 80 and over, Cluster Analysis, Disease Progression, Female, Fibroblast Growth Factors genetics, Hepatocyte Growth Factor genetics, Humans, Male, Middle Aged, Prospective Studies, Proto-Oncogene Proteins c-met genetics, Receptors, Fibroblast Growth Factor genetics, Allelic Imbalance genetics, Carcinoma, Non-Small-Cell Lung genetics, Lung Neoplasms genetics
Abstract

Fibroblast growth factors (FGF), hepatocyte growth factor (HGF) and their receptors, FGFR and c-Met, are essential components of the regulatory networks between the epithelium and mesenchyme in embryonic lung, but their respective roles in tumour growth are not clear. We performed allelotyping at loci containing the candidate genes FGFR-1-2-3-4, FGF-1-2-7-10, c-Met and HGF in 36 non-small cell lung cancer (NSCLC) (20 squamous-cell carcinomas (SQC) and 16 adenocarcinomas (ADC)), by surrounding each locus with two microsatellites (MS), as close as possible to the genes of interest. Unexpectedly, SQC and ADC were frequently altered at all of these loci, and SQC showed more simultaneously altered loci. In ADC, alterations at the 15q13-22 locus (FGF7 candidate gene) were significantly more frequent. Thus, these loci showed different patterns of molecular alterations between SQC and ADC. Finally, alterations at loci containing FGFR and HGF candidate genes were inversely correlated to the lymph node status in SQC and ADC, respectively.

Published
2003
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49. Analysis of allelic imbalance in patients with colorectal cancer according to stage and presence of synchronous liver metastases.

Author

Weber JC, Schneider A, Rohr S, Nakano H, Bachellier P, Méchine A, Hamel G, Kanor M, Chenard MP, Gaub MP, Oudet P, Meyer C, and Jaeck D

Subjects
Adult, Aged, Aged, 80 and over, Colorectal Neoplasms pathology, Disease Progression, Female, Gene Frequency, Humans, Male, Microsatellite Repeats genetics, Middle Aged, Polymerase Chain Reaction, Prognosis, Allelic Imbalance, Colorectal Neoplasms genetics, Liver Neoplasms secondary
Abstract

Objective: To investigate the relationship between number and location of allelic imbalances (AI) and local tumor progression according to Astler-Coller classification., Summary Background Data: Spontaneous errors in DNA replication (i.e., allelic imbalance or microsatellite instability) have been suggested to play an important role in carcinomatous transformation as reflecting alterations of gene function., Methods: One hundred two consecutive patients with colorectal carcinoma undergoing surgical resection were included in this study. Patients were distributed according to the Astler-Coller classification as stages A (n = 7), B1 (n = 15), B2 (n = 24), C (n = 31), and D (n = 25). Fluorescent polymerase chain reaction was performed on frozen tumor, normal colon mucosa, and blood DNA at 35 microsatellite markers. Allelic imbalance frequency was compared with tumor staging., Results: The percentage of AI was significantly higher in stage D than in A/B1 and B2. In addition, the percentage of AI was significantly higher in 10 synchronous colorectal liver metastases than in stage A/B1 and B2 tumors. However, the allelotyping revealed a subgroup of A/B1 tumors with a high AI frequency. Statistical analysis showed that the presence of AI at microsatellites D1S305, D2S138, D3S1282, D17S790, and D22S928 presented a significantly positive correlation with stages., Conclusion: The frequency of AI significantly correlates with tumor progression of colorectal cancer. Primary tumors with synchronous colorectal liver metastases showed a higher percentage of AI, suggesting that a frequency of AI greater than 35% with this selection of markers indicates a high risk of local progression and of development of metastases.

Published
2001
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