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482 results on '"Gatti, Monica"'

10. The Microbial Community of Natural Whey Starter: Why Is It a Driver for the Production of the Most Famous Italian Long-Ripened Cheeses?

Author

Neviani, Erasmo, Levante, Alessia, and Gatti, Monica

Subjects
BIOTIC communities, ARRAIGNMENT, CHEESE, MICROBIAL communities, CHEESEMAKING, ABIOTIC stress, WHEY
Abstract

The remarkable global diversity in long-ripened cheese production can be attributed to the adaptability of the cheese microbiota. Most cheese types involve intricate microbial ecosystems, primarily represented by lactic acid bacteria (LAB). The present study aims to review the microbial community's diversity in dairy fermentation processes, focusing on two famous Italian cheeses, Grana Padano and Parmigiano Reggiano, produced using natural whey starter (NWS). NWS, created by retaining whey from the previous day's cheese batches, forms a microbiological connection between daily cheese productions. Through this technique, a dynamic microbiota colonizes the curd and influences cheese ripening. The back-slopping method in NWS preparation ensures the survival of diverse biotypes, providing a complex microbial community in which interactions among microorganisms are critical to ensuring its technological functionality. As highlighted in this review, the presence of microbial cells alone does not guarantee technological relevance. Critical microorganisms can grow and colonize the curd and cheese. This complexity enables NWS to adapt to artisanal production technologies while considering variations in raw milk microbiota, inhibitory compounds, and manufacturing conditions. This critical review aims to discuss NWS as a key factor in cheese making, considering microbial communities' ability to evolve under different selective pressures and biotic and abiotic stresses. [ABSTRACT FROM AUTHOR]

Published
2024
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14. A Measure to Assess Individual Differences for Disgust Sensitivity: An Italian Version of the Disgust Scale - Revised

Author

Giampietro, Marina, Ruggi, Simona, Caravita, Simona C. S., Gatti, Monica, Colombo, Lucia, and Gilli, Gabriella M.

Subjects
Aversion -- Social aspects -- Measurement, Obsessive-compulsive disorder -- Diagnosis, Psychology and mental health
Abstract

The aim of this study was to examine the psychometric properties of the Disgust Scale-Revised (DS-R) in a large community sample in Italy. Participants (845 Italians, aged 20-46; 50.1% women) completed a battery of self-report questionnaires: the DS-R, the State-Trait Anxiety Inventory, the Big Five Observer, and the Padua Inventory. Exploratory and confirmatory factor analyses supported a six-factor dimensionality of the DS-R in the Italian population. The six-factor structure was partially scalar invariant across gender groups. The data provided some evidence of the scale's reliability for the sample. Correlations of the DS-R score with the assessed personality dimensions were consistent with the disgust literature. The six-factor dimensionality of the Italian version of the DS-R included the Animal reminder factor, which has also been found in other cultures. The second factor, which we named 'Contamination by food,' only partially overlapped the Contamination factor of previous samples. The four remaining factors seemed to assess distinct facets of the Core disgust factor. This also emerged in previous studies. For these four, there was only a partial overlap between the Italian and other populations, suggesting the relevance of cultural differences in the assessment of disgust., Author(s): Marina Giampietro [sup.1] , Simona Ruggi [sup.1] , Simona C. S. Caravita [sup.1] , Monica Gatti [sup.1] , Lucia Colombo [sup.1] , Gabriella M. Gilli [sup.1] Author Affiliations: (Aff1) [...]

Published
2019
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29. Peptide profile of Parmigiano Reggiano cheese after simulated gastrointestinal digestion: From quality drivers to functional compounds

Author

Castellone, Vincenzo, Prandi, Barbara, Bancalari, Elena, Tedeschi, Tullia, Gatti, Monica, and Bottari, Benedetta

Subjects
Microbiology (medical), Microbiology
Abstract

Time of ripening has a strong impact on shaping the valuable and recognizable characteristics of long-ripened types of cheese such as Parmigiano Reggiano (PR) due to the interrelationship between microbiota and proteolysis that occurs during ripening. The derived peptide profile is linked to cheese quality and represents the canvas for enzymes upon digestion, which could be responsible for the release of potentially bioactive peptides (BPs). In this study, we aimed at investigating the presence of BP in 72 PR cheese samples of different ripening times, from curd to 24 months of ripening, produced in six different dairies, and following their fate after simulated gastrointestinal digestion. A small number of peptide sequences sharing 100% similarity with known antimicrobial, antioxidant, and ACE-inhibitor sequences were found in PR cheeses, while a higher number of potential BPs were found after their simulated gastrointestinal digestion, in different amounts according to ripening time. Taking advantage of the complex organization of the sampling plan, we were able to follow the fate of peptides considered quality drivers during cheese ripening to their release as functional compounds upon digestion.

Published
2022
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43. Eating fermented : Health benefits of lab-fermented foods

Author

Castellone, Vincenzo, Bancalari, Elena, Rubert, Josep, Gatti, Monica, Neviani, Erasmo, Bottari, Benedetta, Castellone, Vincenzo, Bancalari, Elena, Rubert, Josep, Gatti, Monica, Neviani, Erasmo, and Bottari, Benedetta

Abstract

Lactic acid bacteria (LAB) are involved in producing a considerable number of fermented products consumed worldwide. Many of those LAB fermented foods are recognized as beneficial for human health due to probiotic LAB or their metabolites produced during food fermentation or after food digestion. In this review, we aim to gather and discuss available information on the health-related effects of LAB-fermented foods. In particular, we focused on the most widely consumed LAB-fermented foods such as yoghurt, kefir, cheese, and plant-based products such as sauerkrauts and kimchi.

Published
2021

45. Differential efficacy of SSTR1, -2, and -5 agonists in the inhibition of C6 glioma growth in nude mice

Author

Barbieri, Federica, Pattarozzi, Alessandra, Gatti, Monica, Aiello, Cinzia, Quintero, Ana, Lunardi, Gianluigi, Bajetto, Adriana, Ferrari, Angelo, Culler, Michael D., and Florio, Tullio

Subjects
Gliomas -- Growth, Gliomas -- Prevention, Somatostatin -- Health aspects, Hormone receptors -- Health aspects, Company growth, Biological sciences
Abstract

Somatostatin receptors (SSTR1-5) mediate antiproliferative effects. In C6 rat glioma cells, somatostatin is cytostatic in vitro via phosphotyrosine phosphatase-dependent inhibition of ERK1/2 activity mediated by SSTR1, -2, and -5. Here we analyzed the effects of SSTR activation on C6 glioma growth in vivo and the intracellular mechanisms involved, comparing somatostatin effects with selective agonists for SSTR1, -2, and -5 (BIM-23745, BIM-23120, BIM-23206) or receptor biselective compounds (SSTR1 and -2, BIM-23704; and SSTR2 and -5, BIM-23190). Nude mice subcutaneously xenografted with C6 cells were treated with somatostatin, SSTR agonists (50 [micro]g, twice/day), or vehicle. Tumor growth was evaluated every 3 days for 19 days. The intracellular pathways responsible of SSTR effects in vivo were evaluated measuring Ki-67, phospho-ERK1/2, and [p27.sup.kip1] expression by immunohistochemistry in sections from explanted tumors. Somatostatin and SSTR1, -2, and -5 agonists strongly inhibited in vivo C6 tumor growth, intratumoral neovessel formation, Ki-67 expression, and ERK1/2 phosphorylation and induced upregulation of [p27.sup.Kipl], whereas only a modest activation of caspase-3 was observed. Somatostatin (acting on SSTR1, -2, and -5) displayed the highest efficacy; SSTR5 selective agonist showed a stronger effect than SSTR1 agonist, and SSTR2 agonist was less effective. On the other hand, SSTR1 and -2 agonists maximally reduced tumor neovasculafization. The combined activation of SSTR1 and -2 showed a synergistic activity, reaching a higher efficacy than BIM-23206, whereas the simultaneous activation of SSTR2 and -5 resulted in a response resembling SSTR5 effects. Thus the simultaneous activation of different SSTRs inhibits glioma cell proliferation in vivo through both direct cytotostatic and antiangiogenic effects. somatostatin; somatostatin receptor; glioblastoma; antiproliferative activity; in vivo; extracellular signal-regulated kinase 1/2 doi: 10.1152/ajpendo.00292.2009.

Published
2009

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