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2. First-principles calculations of graphene nanoribbons in gaseous environments: Structural and electronic properties

Author

Vanin, M., Gath, J., Thygesen, K. S., and Jacobsen, K. W.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

The stability of graphene nanoribbons in the presence of typical atmospheric molecules is systematically investigated by means of density functional theory. We calculate the edge formation free energy of five different edge configurations passivated by H, H$_2$, O, O$_2$, N$_2$, CO, CO$_2$, and H$_2$O, respectively. In addition to the well known hydrogen passivated armchair and zig-zag edges, we find the zig-zag edge saturated by oxygen atoms to be particularly stable under atmospheric conditions. Saturation by oxygen leads to the formation of metallic states strictly localized on the oxygen atoms. Finally, the vibrational spectrum of the hydrogen and oxygen passivated ribbons are calculated and compared.

Published
2010
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3. Cancer, Fertility and Me : Developing and Testing a Novel Fertility Preservation Patient Decision Aid to Support Women at Risk of Losing Their Fertility Because of Cancer Treatment

Author

Jones, G.L., Moss, R.H., Darby, F., Mahmoodi, N., Phillips, B., Hughes, J., Vogt, K.S., Greenfield, D.M., Brauten-Smith, G., Gath, J., Campbell, T., Stark, D., Velikova, G., Snowden, J.A., Baskind, E., Mascerenhas, M., Yeomanson, D., Skull, J., Lane, S., Bekker, H.L., and Anderson, R.A.

Subjects
Cancer Research, Oncology, patient decision aid, fertility preservation, cancer, women, gonadotoxic treatment, survivorship, mixed-method study
Abstract

BackgroundWomen with a new cancer diagnosis face complex decisions about interventions aiming to preserve their fertility. Decision aids are more effective in supporting decision making than traditional information provision. We describe the development and field testing of a novel patient decision aid designed to support women to make fertility preservation treatment decisions around cancer diagnosis.MethodsA prospective, mixed-method, three stage study involving: 1) co-development of the resource in collaboration with a multi-disciplinary group of key stakeholders including oncology and fertility healthcare professionals and patient partners (n=24), 2) alpha testing with a group of cancer patients who had faced a fertility preservation treatment decision in the past (n=11), and oncology and fertility healthcare professionals and stakeholders (n=14) and, 3) beta testing with women in routine care who had received a recent diagnosis of cancer and were facing a fertility preservation treatment decision (n=41) and their oncology and fertility healthcare professionals (n=3). Ten service users recruited from a closed Breast Cancer Now Facebook group and the support group Cancer and Fertility UK also provided feedback on CFM via an online survey.ResultsA 60-page paper prototype of the Cancer, Fertility and Me patient decision aid was initially developed. Alpha testing of the resource found that overall, it was acceptable to cancer patients, healthcare professionals and key stakeholders and it was considered a useful resource to support fertility preservation treatment decision-making. However, the healthcare professionals felt that the length of the patient decision aid, and elements of its content may be a barrier to its use. Subsequently, the prototype was reduced to 40 pages. During beta testing of the shortened version in routine care, women who received the resource described its positive impact on their ability to make fertility preservation decisions and support them at a stressful time. However, practical difficulties emerged which impacted upon its wider dissemination in clinical practice and limited some elements of the evaluation planned.DiscussionWomen receiving the decision aid within the cancer treatment pathway found it helped them engage with decisions about fertility preservation, and make better informed, values-based care plans with oncology and fertility teams. More work is needed to address access and implementation of this resource as part of routine oncology care pathways.

Published
2022

4. Cancer, Fertility and Me: developing and testing a novel fertility preservation patient decision aid to support women at risk of losing their fertility because of cancer treatment

Author

Jones, G, Moss, R, Darby, F, Mahmoodi, N, Phillips, B, Hughes, J, Vogt, K, Greenfield, D, Brauten-Smith, G, Gath, J, Campbell, T, Stark, D, Velikova, G, Snowden, J, Baskind, E, Mascerenhas, M, Yeomanson, D, Skull, J, Lane, S, Bekker, H, Anderson, R, Jones, G, Moss, R, Darby, F, Mahmoodi, N, Phillips, B, Hughes, J, Vogt, K, Greenfield, D, Brauten-Smith, G, Gath, J, Campbell, T, Stark, D, Velikova, G, Snowden, J, Baskind, E, Mascerenhas, M, Yeomanson, D, Skull, J, Lane, S, Bekker, H, and Anderson, R

Abstract

Background: Women with a new cancer diagnosis face complex decisions about interventions aiming to preserve their fertility. Decision aids are more effective in supporting decision making than traditional information provision. We describe the development and field testing of a novel patient decision aid designed to support women to make fertility preservation treatment decisions around cancer diagnosis. Methods: A prospective, mixed-method, three stage study involving: 1) co-development of the resource in collaboration with a multi-disciplinary group of key stakeholders including oncology and fertility healthcare professionals and patient partners (n=24), 2) alpha testing with a group of cancer patients who had faced a fertility preservation treatment decision in the past (n=11), and oncology and fertility healthcare professionals and stakeholders (n=14) and, 3) beta testing with women in routine care who had received a recent diagnosis of cancer and were facing a fertility preservation treatment decision (n=41) and their oncology and fertility healthcare professionals (n=3). Ten service users recruited from a closed Breast Cancer Now Facebook group and the support group Cancer and Fertility UK also provided feedback on CFM via an online survey. Results: A 60-page paper prototype of the Cancer, Fertility and Me patient decision aid was initially developed. Alpha testing of the resource found that overall, it was acceptable to cancer patients, healthcare professionals and key stakeholders and it was considered a useful resource to support fertility preservation treatment decision-making. However, the healthcare professionals felt that the length of the patient decision aid, and elements of its content may be a barrier to its use. Subsequently, the prototype was reduced to 40 pages. During beta testing of the shortened version in routine care, women who received the resource described its positive impact on their ability to make fertility preservation decisions and s

Published
2022

5. Dependence on plasma shape and plasma fueling for small edge-localized mode regimes in TCV and ASDEX Upgrade

Author

Labit, B, Eich, T, Harrer, G, Wolfrum, E, Bernert, M, Dunne, M, Frassinetti, L, Hennequin, P, Maurizio, R, Merle, A, Meyer, H, Saarelma, S, Sheikh, U, Adamek, J, Agostini, M, Aguiam, D, Akers, R, Albanese, R, Albert, C, Alessi, E, Ambrosino, R, Andr be, Y, Angioni, C, Apruzzese, G, Aradi, M, Arnichand, H, Auriemma, F, Avdeeva, G, Ayllon-Guerola, J, Bagnato, F, Bandaru, V, Barnes, M, Barrera-Orte, L, Bettini, P, Bilato, R, Biletskyi, O, Bilkova, P, Bin, W, Blanchard, P, Blanken, T, Bobkov, V, Bock, A, Boeyaert, D, Bogar, K, Bogar, O, Bohm, P, Bolzonella, T, Bombarda, F, Boncagni, L, Bouquey, F, Bowman, C, Brezinsek, S, Brida, D, Brunetti, D, Bucalossi, J, Buchanan, J, Buermans, J, Bufferand, H, Buller, S, Buratti, P, Burckhart, A, Calabr, G, Calacci, L, Camenen, Y, Cannas, B, Cano Megias, P, Carnevale, D, Carpanese, F, Carr, M, Carralero, D, Carraro, L, Casolari, A, Cathey, A, Causa, F, Cavedon, M, Cecconello, M, Ceccuzzi, S, Cerovsky, J, Chapman, S, Chmielewski, P, Choi, D, Cianfarani, C, Ciraolo, G, Coda, S, Coelho, R, Colas, L, Colette, D, Cordaro, L, Cordella, F, Costea, S, Coster, D, Cruz Zabala, D, Cseh, G, Czarnecka, A, Cziegler, I, D'Arcangelo, O, Dal Molin, A, David, P, De Carolis, G, De Oliveira, H, Decker, J, Dejarnac, R, Delogu, R, Den Harder, N, Dimitrova, M, Dolizy, F, Dominguez-Palacios Duran, J, Douai, D, Drenik, A, Dreval, M, Dudson, B, Dunai, D, Duval, B, Dux, R, Elmore, S, Embreus, O, Erds, B, Fable, E, Faitsch, M, Fanni, A, Farnik, M, Faust, I, Faustin, J, Fedorczak, N, Felici, F, Feng, S, Feng, X, Ferreira, J, Ferr, G, Fevrier, O, Ficker, O, Figini, L, Figueiredo, A, Fil, A, Fontana, M, Francesco, M, Fuchs, C, Futatani, S, Gabellieri, L, Gadariya, D, Gahle, D, Galassi, D, Galazka, K, Galdon-Quiroga, J, Galeani, S, Gallart, D, Gallo, A, Galperti, C, Garavaglia, S, Garcia, J, Garcia-Lopez, J, Garcia-Mu oz, M, Garzotti, L, Gath, J, Geiger, B, Giacomelli, L, Giannone, L, Gibson, S, Gil, L, Giovannozzi, E, Giruzzi, G, Gobbin, M, Gonzalez-Martin, J, Goodman, T, Gorini, G, Gospodarczyk, M, Granucci, G, Grekov, D, Grenfell, G, Griener, M, Groth, M, Grover, O, Gruca, M, Gude, A, Guimarais, L, Gyergyek, T, Hacek, P, Hakola, A, Ham, C, Happel, T, Harrison, J, Havranek, A, Hawke, J, Henderson, S, Hesslow, L, Hitzler, F, Hnat, B, Hobirk, J, Hoelzl, M, Hogeweij, D, Hopf, C, Hoppe, M, Horacek, J, Hron, M, Huang, Z, Iantchenko, A, Iglesias, D, Igochine, V, Innocente, P, Ionita-Schrittwieser, C, Isliker, H, Ivanova-Stanik, I, Jacobsen, A, Jakubowski, M, Janky, F, Jardin, A, Jaulmes, F, Jensen, T, Jonsson, T, Kallenbach, A, Kappatou, A, Karpushov, A, Kasilov, S, Kazakov, Y, Kazantzidis, P, Keeling, D, Kelemen, M, Kendl, A, Kernbichler, W, Kirk, A, Kocsis, G, Komm, M, Kong, M, Korovin, V, Koubiti, M, Kovacic, J, Krawczyk, N, Krieger, K, Kripner, L, Krivska, A, Kudlacek, O, Kulyk, Y, Kurki-Suonio, T, Kwiatkowski, R, Laggner, F, Laguardia, L, Lahtinen, A, Lang, P, Likonen, J, Lipschultz, B, Liu, F, Lombroni, R, Lorenzini, R, Loschiavo, V, Lunt, T, Macusova, E, Madsen, J, Maggiora, R, Maljaars, B, Manas, P, Mantica, P, Mantsinen, M, Manz, P, Maraschek, M, Marchenko, V, Marchetto, C, Mariani, A, Marini, C, Markovic, T, Marrelli, L, Martin, P, Martin Solis, J, Martitsch, A, Mastrostefano, S, Matos, F, Matthews, G, Mayoral, M, Mazon, D, Mazzotta, C, Mc Carthy, P, Mcclements, K, Mcdermott, R, Mcmillan, B, Meineri, C, Menkovski, V, Meshcheriakov, D, Messmer, M, Micheletti, D, Milanesio, D, Militello, F, Miron, I, Mlynar, J, Moiseenko, V, Molina Cabrera, P, Morales, J, Moret, J, Moro, A, Moulton, D, Nabais, F, Naulin, V, Naydenkova, D, Nem, R, Nespoli, F, Newton, S, Nielsen, A, Nielsen, S, Nikolaeva, V, Nocente, M, Nowak, S, Oberkofler, M, Ochoukov, R, Ollus, P, Olsen, J, Omotani, J, Ongena, J, Orain, F, Orsitto, F, Paccagnella, R, Palha, A, Panaccione, L, Panek, R, Panjan, M, Papp, G, Paradela Perez, I, Parra, F, Passeri, M, Pau, A, Pautasso, G, Pavlichenko, R, Perek, A, Pericoli Radolfini, V, Pesamosca, F, Peterka, M, Petrzilka, V, Piergotti, V, Pigatto, L, Piovesan, P, Piron, C, Piron, L, Plyusnin, V, Pokol, G, Poli, E, Poloskei, P, Popov, T, Popovic, Z, Por, G, Porte, L, Pucella, G, Puiatti, M, Putterich, T, Rabinski, M, Juul Rasmussen, J, Rasmussen, J, Ratta, G, Ratynskaia, S, Ravensbergen, T, Refy, D, Reich, M, Reimerdes, H, Reimold, F, Reiser, D, Reux, C, Reznik, S, Ricci, D, Rispoli, N, Rivero-Rodriguez, J, Rocchi, G, Rodriguez-Ramos, M, Romano, A, Rosato, J, Rubinacci, G, Rubino, G, Ryan, D, Salewski, M, Salmi, A, Samaddar, D, Sanchis-Sanchez, L, Santos, J, Sarkimaki, K, Sassano, M, Sauter, O, Scannell, R, Scheffer, M, Schneider, B, Schneider, P, Schrittwieser, R, Schubert, M, Seidl, J, Seliunin, E, Sharapov, S, Sheeba, R, Sias, G, Sieglin, B, Silva, C, Sipila, S, Smith, S, Snicker, A, Solano, E, Hansen, S, Soria-Hoyo, C, Sorokovoy, E, Sozzi, C, Sperduti, A, Spizzo, G, Spolaore, M, Stejner, M, Stipani, L, Stober, J, Strand, P, Sun, H, Suttrop, W, Sytnykov, D, Szepesi, T, Tal, B, Tala, T, Tardini, G, Tardocchi, M, Teplukhina, A, Terranova, D, Testa, D, Theiler, C, Thoren, E, Thornton, A, Tilia, B, Tolias, P, Tomes, M, Toscano-Jimenez, M, Tsironis, C, Tsui, C, Tudisco, O, Urban, J, Valisa, M, Vallar, M, Vallejos Olivares, P, Valovic, M, Van Vugt, D, Vanovac, B, Varje, J, Varju, J, Varoutis, S, Vartanian, S, Vasilovici, O, Vega, J, Verdoolaege, G, Verhaegh, K, Vermare, L, Vianello, N, Vicente, J, Viezzer, E, Villone, F, Voitsekhovitch, I, Voltolina, D, Vondracek, P, Vu, N, Walkden, N, Wauters, T, Weiland, M, Weinzettl, V, Wensing, M, Wiesen, S, Wiesenberger, M, Wilkie, G, Willensdorfer, M, Wischmeier, M, Wu, K, Xiang, L, Zagorski, R, Zaloga, D, Zanca, P, Zaplotnik, R, Zebrowski, J, Zhang, W, Zisis, A, Zoletnik, S, Zuin, M, Labit B., Eich T., Harrer G. F., Wolfrum E., Bernert M., Dunne M. G., Frassinetti L., Hennequin P., Maurizio R., Merle A., Meyer H., Saarelma S., Sheikh U., Adamek J., Agostini M., Aguiam D., Akers R., Albanese R., Albert C., Alessi E., Ambrosino R., Andr be Y., Angioni C., Apruzzese G., Aradi M., Arnichand H., Auriemma F., Avdeeva G., Ayllon-Guerola J. M., Bagnato F., Bandaru V. K., Barnes M., Barrera-Orte L., Bettini P., Bilato R., Biletskyi O., Bilkova P., Bin W., Blanchard P., Blanken T., Bobkov V., Bock A., Boeyaert D., Bogar K., Bogar O., Bohm P., Bolzonella T., Bombarda F., Boncagni L., Bouquey F., Bowman C., Brezinsek S., Brida D., Brunetti D., Bucalossi J., Buchanan J., Buermans J., Bufferand H., Buller S., Buratti P., Burckhart A., Calabr G., Calacci L., Camenen Y., Cannas B., Cano Megias P., Carnevale D., Carpanese F., Carr M., Carralero D., Carraro L., Casolari A., Cathey A., Causa F., Cavedon M., Cecconello M., Ceccuzzi S., Cerovsky J., Chapman S., Chmielewski P., Choi D., Cianfarani C., Ciraolo G., Coda S., Coelho R., Colas L., Colette D., Cordaro L., Cordella F., Costea S., Coster D., Cruz Zabala D. J., Cseh G., Czarnecka A., Cziegler I., D'Arcangelo O., Dal Molin A., David P., De Carolis G., De Oliveira H., Decker J., Dejarnac R., Delogu R., Den Harder N., Dimitrova M., Dolizy F., Dominguez-Palacios Duran J. J., Douai D., Drenik A., Dreval M., Dudson B., Dunai D., Duval B. P., Dux R., Elmore S., Embreus O., Erds B., Fable E., Faitsch M., Fanni A., Farnik M., Faust I., Faustin J., Fedorczak N., Felici F., Feng S., Feng X., Ferreira J., Ferr G., Fevrier O., Ficker O., Figini L., Figueiredo A., Fil A., Fontana M., Francesco M., Fuchs C., Futatani S., Gabellieri L., Gadariya D., Gahle D., Galassi D., Galazka K., Galdon-Quiroga J., Galeani S., Gallart D., Gallo A., Galperti C., Garavaglia S., Garcia J., Garcia-Lopez J., Garcia-Mu oz M., Garzotti L., Gath J., Geiger B., Giacomelli L., Giannone L., Gibson S., Gil L., Giovannozzi E., Giruzzi G., Gobbin M., Gonzalez-Martin J., Goodman T. P., Gorini G., Gospodarczyk M., GRANUCCI, GUSTAVO, Grekov D., Grenfell G., Griener M., Groth M., Grover O., Gruca M., Gude A., Guimarais L., Gyergyek T., Hacek P., Hakola A., Ham C., Happel T., Harrison J., Havranek A., Hawke J., Henderson S., Hesslow L., Hitzler F., Hnat B., Hobirk J., Hoelzl M., Hogeweij D., Hopf C., Hoppe M., Horacek J., Hron M., Huang Z., Iantchenko A., Iglesias D., Igochine V., Innocente P., Ionita-Schrittwieser C., Isliker H., Ivanova-Stanik I., Jacobsen A., Jakubowski M., Janky F., Jardin A., Jaulmes F., Jensen T., Jonsson T., Kallenbach A., Kappatou A., Karpushov A., Kasilov S., Kazakov Y., Kazantzidis P. V., Keeling D., Kelemen M., Kendl A., Kernbichler W., Kirk A., Kocsis G., Komm M., Kong M., Korovin V., Koubiti M., Kovacic J., Krawczyk N., Krieger K., Kripner L., Krivska A., Kudlacek O., Kulyk Y., Kurki-Suonio T., Kwiatkowski R., Laggner F., Laguardia L., Lahtinen A., Lang P., Likonen J., Lipschultz B., Liu F., Lombroni R., Lorenzini R., Loschiavo V. P., Lunt T., MacUsova E., Madsen J., Maggiora R., Maljaars B., Manas P., Mantica P., Mantsinen M. J., Manz P., Maraschek M., Marchenko V., Marchetto C., MARIANI, ALBERTO, Marini C., Markovic T., Marrelli L., Martin P., Martin Solis J. R., Martitsch A., Mastrostefano S., Matos F., Matthews G., Mayoral M. -L., Mazon D., Mazzotta C., Mc Carthy P., McClements K., McDermott R., McMillan B., Meineri C., Menkovski V., Meshcheriakov D., Messmer M., Micheletti D., Milanesio D., Militello F., Miron I. G., Mlynar J., Moiseenko V., Molina Cabrera P. A., Morales J., Moret J. -M., Moro A., Moulton D., Nabais F., Naulin V., Naydenkova D., Nem R. D., Nespoli F., Newton S., Nielsen A. H., Nielsen S. K., Nikolaeva V., Nocente M., Nowak S., Oberkofler M., Ochoukov R., Ollus P., Olsen J., Omotani J., Ongena J., Orain F., Orsitto F. P., Paccagnella R., Palha A., Panaccione L., Panek R., Panjan M., Papp G., Paradela Perez I., Parra F., Passeri M., Pau A., Pautasso G., Pavlichenko R., Perek A., Pericoli Radolfini V., Pesamosca F., Peterka M., Petrzilka V., Piergotti V., Pigatto L., Piovesan P., Piron C., Piron L., Plyusnin V., Pokol G., Poli E., Poloskei P., Popov T., Popovic Z., Por G., Porte L., Pucella G., Puiatti M. E., Putterich T., Rabinski M., Juul Rasmussen J., Rasmussen J., Ratta G. A., Ratynskaia S., Ravensbergen T., Refy D., Reich M., Reimerdes H., Reimold F., Reiser D., Reux C., Reznik S., Ricci D., Rispoli N., Rivero-Rodriguez J. F., Rocchi G., Rodriguez-Ramos M., Romano A., Rosato J., Rubinacci G., Rubino G., Ryan D. A., Salewski M., Salmi A., Samaddar D., Sanchis-Sanchez L., Santos J., Sarkimaki K., Sassano M., Sauter O., Scannell R., Scheffer M., Schneider B. S., Schneider P., Schrittwieser R., Schubert M., Seidl J., Seliunin E., Sharapov S., Sheeba R. R., Sias G., Sieglin B., Silva C., Sipila S., Smith S., Snicker A., Solano E. R., Hansen S. K., Soria-Hoyo C., Sorokovoy E., Sozzi C., Sperduti A., Spizzo G., Spolaore M., Stejner M., Stipani L., Stober J., Strand P., Sun H., Suttrop W., Sytnykov D., Szepesi T., Tal B., Tala T., Tardini G., Tardocchi M., Teplukhina A., Terranova D., Testa D., Theiler C., Thoren E., Thornton A., Tilia B., Tolias P., Tomes M., Toscano-Jimenez M., Tsironis C., Tsui C., Tudisco O., Urban J., Valisa M., Vallar M., Vallejos Olivares P., Valovic M., Van Vugt D., Vanovac B., Varje J., Varju J., Varoutis S., Vartanian S., Vasilovici O., Vega J., Verdoolaege G., Verhaegh K., Vermare L., Vianello N., Vicente J., Viezzer E., Villone F., Voitsekhovitch I., Voltolina D., Vondracek P., Vu N. M. T., Walkden N., Wauters T., Weiland M., Weinzettl V., Wensing M., Wiesen S., Wiesenberger M., Wilkie G., Willensdorfer M., Wischmeier M., Wu K., Xiang L., Zagorski R., Zaloga D., Zanca P., Zaplotnik R., Zebrowski J., Zhang W., Zisis A., Zoletnik S., Zuin M., Labit, B, Eich, T, Harrer, G, Wolfrum, E, Bernert, M, Dunne, M, Frassinetti, L, Hennequin, P, Maurizio, R, Merle, A, Meyer, H, Saarelma, S, Sheikh, U, Adamek, J, Agostini, M, Aguiam, D, Akers, R, Albanese, R, Albert, C, Alessi, E, Ambrosino, R, Andr be, Y, Angioni, C, Apruzzese, G, Aradi, M, Arnichand, H, Auriemma, F, Avdeeva, G, Ayllon-Guerola, J, Bagnato, F, Bandaru, V, Barnes, M, Barrera-Orte, L, Bettini, P, Bilato, R, Biletskyi, O, Bilkova, P, Bin, W, Blanchard, P, Blanken, T, Bobkov, V, Bock, A, Boeyaert, D, Bogar, K, Bogar, O, Bohm, P, Bolzonella, T, Bombarda, F, Boncagni, L, Bouquey, F, Bowman, C, Brezinsek, S, Brida, D, Brunetti, D, Bucalossi, J, Buchanan, J, Buermans, J, Bufferand, H, Buller, S, Buratti, P, Burckhart, A, Calabr, G, Calacci, L, Camenen, Y, Cannas, B, Cano Megias, P, Carnevale, D, Carpanese, F, Carr, M, Carralero, D, Carraro, L, Casolari, A, Cathey, A, Causa, F, Cavedon, M, Cecconello, M, Ceccuzzi, S, Cerovsky, J, Chapman, S, Chmielewski, P, Choi, D, Cianfarani, C, Ciraolo, G, Coda, S, Coelho, R, Colas, L, Colette, D, Cordaro, L, Cordella, F, Costea, S, Coster, D, Cruz Zabala, D, Cseh, G, Czarnecka, A, Cziegler, I, D'Arcangelo, O, Dal Molin, A, David, P, De Carolis, G, De Oliveira, H, Decker, J, Dejarnac, R, Delogu, R, Den Harder, N, Dimitrova, M, Dolizy, F, Dominguez-Palacios Duran, J, Douai, D, Drenik, A, Dreval, M, Dudson, B, Dunai, D, Duval, B, Dux, R, Elmore, S, Embreus, O, Erds, B, Fable, E, Faitsch, M, Fanni, A, Farnik, M, Faust, I, Faustin, J, Fedorczak, N, Felici, F, Feng, S, Feng, X, Ferreira, J, Ferr, G, Fevrier, O, Ficker, O, Figini, L, Figueiredo, A, Fil, A, Fontana, M, Francesco, M, Fuchs, C, Futatani, S, Gabellieri, L, Gadariya, D, Gahle, D, Galassi, D, Galazka, K, Galdon-Quiroga, J, Galeani, S, Gallart, D, Gallo, A, Galperti, C, Garavaglia, S, Garcia, J, Garcia-Lopez, J, Garcia-Mu oz, M, Garzotti, L, Gath, J, Geiger, B, Giacomelli, L, Giannone, L, Gibson, S, Gil, L, Giovannozzi, E, Giruzzi, G, Gobbin, M, Gonzalez-Martin, J, Goodman, T, Gorini, G, Gospodarczyk, M, Granucci, G, Grekov, D, Grenfell, G, Griener, M, Groth, M, Grover, O, Gruca, M, Gude, A, Guimarais, L, Gyergyek, T, Hacek, P, Hakola, A, Ham, C, Happel, T, Harrison, J, Havranek, A, Hawke, J, Henderson, S, Hesslow, L, Hitzler, F, Hnat, B, Hobirk, J, Hoelzl, M, Hogeweij, D, Hopf, C, Hoppe, M, Horacek, J, Hron, M, Huang, Z, Iantchenko, A, Iglesias, D, Igochine, V, Innocente, P, Ionita-Schrittwieser, C, Isliker, H, Ivanova-Stanik, I, Jacobsen, A, Jakubowski, M, Janky, F, Jardin, A, Jaulmes, F, Jensen, T, Jonsson, T, Kallenbach, A, Kappatou, A, Karpushov, A, Kasilov, S, Kazakov, Y, Kazantzidis, P, Keeling, D, Kelemen, M, Kendl, A, Kernbichler, W, Kirk, A, Kocsis, G, Komm, M, Kong, M, Korovin, V, Koubiti, M, Kovacic, J, Krawczyk, N, Krieger, K, Kripner, L, Krivska, A, Kudlacek, O, Kulyk, Y, Kurki-Suonio, T, Kwiatkowski, R, Laggner, F, Laguardia, L, Lahtinen, A, Lang, P, Likonen, J, Lipschultz, B, Liu, F, Lombroni, R, Lorenzini, R, Loschiavo, V, Lunt, T, Macusova, E, Madsen, J, Maggiora, R, Maljaars, B, Manas, P, Mantica, P, Mantsinen, M, Manz, P, Maraschek, M, Marchenko, V, Marchetto, C, Mariani, A, Marini, C, Markovic, T, Marrelli, L, Martin, P, Martin Solis, J, Martitsch, A, Mastrostefano, S, Matos, F, Matthews, G, Mayoral, M, Mazon, D, Mazzotta, C, Mc Carthy, P, Mcclements, K, Mcdermott, R, Mcmillan, B, Meineri, C, Menkovski, V, Meshcheriakov, D, Messmer, M, Micheletti, D, Milanesio, D, Militello, F, Miron, I, Mlynar, J, Moiseenko, V, Molina Cabrera, P, Morales, J, Moret, J, Moro, A, Moulton, D, Nabais, F, Naulin, V, Naydenkova, D, Nem, R, Nespoli, F, Newton, S, Nielsen, A, Nielsen, S, Nikolaeva, V, Nocente, M, Nowak, S, Oberkofler, M, Ochoukov, R, Ollus, P, Olsen, J, Omotani, J, Ongena, J, Orain, F, Orsitto, F, Paccagnella, R, Palha, A, Panaccione, L, Panek, R, Panjan, M, Papp, G, Paradela Perez, I, Parra, F, Passeri, M, Pau, A, Pautasso, G, Pavlichenko, R, Perek, A, Pericoli Radolfini, V, Pesamosca, F, Peterka, M, Petrzilka, V, Piergotti, V, Pigatto, L, Piovesan, P, Piron, C, Piron, L, Plyusnin, V, Pokol, G, Poli, E, Poloskei, P, Popov, T, Popovic, Z, Por, G, Porte, L, Pucella, G, Puiatti, M, Putterich, T, Rabinski, M, Juul Rasmussen, J, Rasmussen, J, Ratta, G, Ratynskaia, S, Ravensbergen, T, Refy, D, Reich, M, Reimerdes, H, Reimold, F, Reiser, D, Reux, C, Reznik, S, Ricci, D, Rispoli, N, Rivero-Rodriguez, J, Rocchi, G, Rodriguez-Ramos, M, Romano, A, Rosato, J, Rubinacci, G, Rubino, G, Ryan, D, Salewski, M, Salmi, A, Samaddar, D, Sanchis-Sanchez, L, Santos, J, Sarkimaki, K, Sassano, M, Sauter, O, Scannell, R, Scheffer, M, Schneider, B, Schneider, P, Schrittwieser, R, Schubert, M, Seidl, J, Seliunin, E, Sharapov, S, Sheeba, R, Sias, G, Sieglin, B, Silva, C, Sipila, S, Smith, S, Snicker, A, Solano, E, Hansen, S, Soria-Hoyo, C, Sorokovoy, E, Sozzi, C, Sperduti, A, Spizzo, G, Spolaore, M, Stejner, M, Stipani, L, Stober, J, Strand, P, Sun, H, Suttrop, W, Sytnykov, D, Szepesi, T, Tal, B, Tala, T, Tardini, G, Tardocchi, M, Teplukhina, A, Terranova, D, Testa, D, Theiler, C, Thoren, E, Thornton, A, Tilia, B, Tolias, P, Tomes, M, Toscano-Jimenez, M, Tsironis, C, Tsui, C, Tudisco, O, Urban, J, Valisa, M, Vallar, M, Vallejos Olivares, P, Valovic, M, Van Vugt, D, Vanovac, B, Varje, J, Varju, J, Varoutis, S, Vartanian, S, Vasilovici, O, Vega, J, Verdoolaege, G, Verhaegh, K, Vermare, L, Vianello, N, Vicente, J, Viezzer, E, Villone, F, Voitsekhovitch, I, Voltolina, D, Vondracek, P, Vu, N, Walkden, N, Wauters, T, Weiland, M, Weinzettl, V, Wensing, M, Wiesen, S, Wiesenberger, M, Wilkie, G, Willensdorfer, M, Wischmeier, M, Wu, K, Xiang, L, Zagorski, R, Zaloga, D, Zanca, P, Zaplotnik, R, Zebrowski, J, Zhang, W, Zisis, A, Zoletnik, S, Zuin, M, Labit B., Eich T., Harrer G. F., Wolfrum E., Bernert M., Dunne M. G., Frassinetti L., Hennequin P., Maurizio R., Merle A., Meyer H., Saarelma S., Sheikh U., Adamek J., Agostini M., Aguiam D., Akers R., Albanese R., Albert C., Alessi E., Ambrosino R., Andr be Y., Angioni C., Apruzzese G., Aradi M., Arnichand H., Auriemma F., Avdeeva G., Ayllon-Guerola J. M., Bagnato F., Bandaru V. K., Barnes M., Barrera-Orte L., Bettini P., Bilato R., Biletskyi O., Bilkova P., Bin W., Blanchard P., Blanken T., Bobkov V., Bock A., Boeyaert D., Bogar K., Bogar O., Bohm P., Bolzonella T., Bombarda F., Boncagni L., Bouquey F., Bowman C., Brezinsek S., Brida D., Brunetti D., Bucalossi J., Buchanan J., Buermans J., Bufferand H., Buller S., Buratti P., Burckhart A., Calabr G., Calacci L., Camenen Y., Cannas B., Cano Megias P., Carnevale D., Carpanese F., Carr M., Carralero D., Carraro L., Casolari A., Cathey A., Causa F., Cavedon M., Cecconello M., Ceccuzzi S., Cerovsky J., Chapman S., Chmielewski P., Choi D., Cianfarani C., Ciraolo G., Coda S., Coelho R., Colas L., Colette D., Cordaro L., Cordella F., Costea S., Coster D., Cruz Zabala D. J., Cseh G., Czarnecka A., Cziegler I., D'Arcangelo O., Dal Molin A., David P., De Carolis G., De Oliveira H., Decker J., Dejarnac R., Delogu R., Den Harder N., Dimitrova M., Dolizy F., Dominguez-Palacios Duran J. J., Douai D., Drenik A., Dreval M., Dudson B., Dunai D., Duval B. P., Dux R., Elmore S., Embreus O., Erds B., Fable E., Faitsch M., Fanni A., Farnik M., Faust I., Faustin J., Fedorczak N., Felici F., Feng S., Feng X., Ferreira J., Ferr G., Fevrier O., Ficker O., Figini L., Figueiredo A., Fil A., Fontana M., Francesco M., Fuchs C., Futatani S., Gabellieri L., Gadariya D., Gahle D., Galassi D., Galazka K., Galdon-Quiroga J., Galeani S., Gallart D., Gallo A., Galperti C., Garavaglia S., Garcia J., Garcia-Lopez J., Garcia-Mu oz M., Garzotti L., Gath J., Geiger B., Giacomelli L., Giannone L., Gibson S., Gil L., Giovannozzi E., Giruzzi G., Gobbin M., Gonzalez-Martin J., Goodman T. P., Gorini G., Gospodarczyk M., GRANUCCI, GUSTAVO, Grekov D., Grenfell G., Griener M., Groth M., Grover O., Gruca M., Gude A., Guimarais L., Gyergyek T., Hacek P., Hakola A., Ham C., Happel T., Harrison J., Havranek A., Hawke J., Henderson S., Hesslow L., Hitzler F., Hnat B., Hobirk J., Hoelzl M., Hogeweij D., Hopf C., Hoppe M., Horacek J., Hron M., Huang Z., Iantchenko A., Iglesias D., Igochine V., Innocente P., Ionita-Schrittwieser C., Isliker H., Ivanova-Stanik I., Jacobsen A., Jakubowski M., Janky F., Jardin A., Jaulmes F., Jensen T., Jonsson T., Kallenbach A., Kappatou A., Karpushov A., Kasilov S., Kazakov Y., Kazantzidis P. V., Keeling D., Kelemen M., Kendl A., Kernbichler W., Kirk A., Kocsis G., Komm M., Kong M., Korovin V., Koubiti M., Kovacic J., Krawczyk N., Krieger K., Kripner L., Krivska A., Kudlacek O., Kulyk Y., Kurki-Suonio T., Kwiatkowski R., Laggner F., Laguardia L., Lahtinen A., Lang P., Likonen J., Lipschultz B., Liu F., Lombroni R., Lorenzini R., Loschiavo V. P., Lunt T., MacUsova E., Madsen J., Maggiora R., Maljaars B., Manas P., Mantica P., Mantsinen M. J., Manz P., Maraschek M., Marchenko V., Marchetto C., MARIANI, ALBERTO, Marini C., Markovic T., Marrelli L., Martin P., Martin Solis J. R., Martitsch A., Mastrostefano S., Matos F., Matthews G., Mayoral M. -L., Mazon D., Mazzotta C., Mc Carthy P., McClements K., McDermott R., McMillan B., Meineri C., Menkovski V., Meshcheriakov D., Messmer M., Micheletti D., Milanesio D., Militello F., Miron I. G., Mlynar J., Moiseenko V., Molina Cabrera P. A., Morales J., Moret J. -M., Moro A., Moulton D., Nabais F., Naulin V., Naydenkova D., Nem R. D., Nespoli F., Newton S., Nielsen A. H., Nielsen S. K., Nikolaeva V., Nocente M., Nowak S., Oberkofler M., Ochoukov R., Ollus P., Olsen J., Omotani J., Ongena J., Orain F., Orsitto F. P., Paccagnella R., Palha A., Panaccione L., Panek R., Panjan M., Papp G., Paradela Perez I., Parra F., Passeri M., Pau A., Pautasso G., Pavlichenko R., Perek A., Pericoli Radolfini V., Pesamosca F., Peterka M., Petrzilka V., Piergotti V., Pigatto L., Piovesan P., Piron C., Piron L., Plyusnin V., Pokol G., Poli E., Poloskei P., Popov T., Popovic Z., Por G., Porte L., Pucella G., Puiatti M. E., Putterich T., Rabinski M., Juul Rasmussen J., Rasmussen J., Ratta G. A., Ratynskaia S., Ravensbergen T., Refy D., Reich M., Reimerdes H., Reimold F., Reiser D., Reux C., Reznik S., Ricci D., Rispoli N., Rivero-Rodriguez J. F., Rocchi G., Rodriguez-Ramos M., Romano A., Rosato J., Rubinacci G., Rubino G., Ryan D. A., Salewski M., Salmi A., Samaddar D., Sanchis-Sanchez L., Santos J., Sarkimaki K., Sassano M., Sauter O., Scannell R., Scheffer M., Schneider B. S., Schneider P., Schrittwieser R., Schubert M., Seidl J., Seliunin E., Sharapov S., Sheeba R. R., Sias G., Sieglin B., Silva C., Sipila S., Smith S., Snicker A., Solano E. R., Hansen S. K., Soria-Hoyo C., Sorokovoy E., Sozzi C., Sperduti A., Spizzo G., Spolaore M., Stejner M., Stipani L., Stober J., Strand P., Sun H., Suttrop W., Sytnykov D., Szepesi T., Tal B., Tala T., Tardini G., Tardocchi M., Teplukhina A., Terranova D., Testa D., Theiler C., Thoren E., Thornton A., Tilia B., Tolias P., Tomes M., Toscano-Jimenez M., Tsironis C., Tsui C., Tudisco O., Urban J., Valisa M., Vallar M., Vallejos Olivares P., Valovic M., Van Vugt D., Vanovac B., Varje J., Varju J., Varoutis S., Vartanian S., Vasilovici O., Vega J., Verdoolaege G., Verhaegh K., Vermare L., Vianello N., Vicente J., Viezzer E., Villone F., Voitsekhovitch I., Voltolina D., Vondracek P., Vu N. M. T., Walkden N., Wauters T., Weiland M., Weinzettl V., Wensing M., Wiesen S., Wiesenberger M., Wilkie G., Willensdorfer M., Wischmeier M., Wu K., Xiang L., Zagorski R., Zaloga D., Zanca P., Zaplotnik R., Zebrowski J., Zhang W., Zisis A., Zoletnik S., and Zuin M.

Abstract

Within the EUROfusion MST1 work package, a series of experiments has been conducted on AUG and TCV devices to disentangle the role of plasma fueling and plasma shape for the onset of small ELM regimes. On both devices, small ELM regimes with high confinement are achieved if and only if two conditions are fulfilled at the same time. Firstly, the plasma density at the separatrix must be large enough (ne,sep/nG ∼ 0.3), leading to a pressure profile flattening at the separatrix, which stabilizes type-I ELMs. Secondly, the magnetic configuration has to be close to a double null (DN), leading to a reduction of the magnetic shear in the extreme vicinity of the separatrix. As a consequence, its stabilizing effect on ballooning modes is weakened.

Published
2019

6. Physics research on the TCV tokamak facility: From conventional to alternative scenarios and beyond

Author

Coda, S, Agostini, M, Albanese, R, Alberti, S, Alessi, E, Allan, S, Allcock, J, Ambrosino, R, Anand, H, Andrebe, Y, Arnichand, H, Auriemma, F, Ayllon-Guerola, J, Bagnato, F, Ball, J, Baquero-Ruiz, M, Beletskii, A, Bernert, M, Bin, W, Blanchard, P, Blanken, T, Boedo, J, Bogar, O, Bolzonella, T, Bombarda, F, Bonanomi, N, Bouquey, F, Bowman, C, Brida, D, Bucalossi, J, Buermans, J, Bufferand, H, Buratti, P, Calabro, G, Calacci, L, Camenen, Y, Carnevale, D, Carpanese, F, Carr, M, Carraro, L, Casolari, A, Causa, F, Cerovsky, J, Chellai, O, Chmielewski, P, Choi, D, Christen, N, Ciraolo, G, Cordaro, L, Costea, S, Cruz, N, Czarnecka, A, Dal Molin, A, David, P, Decker, J, De Oliveira, H, Douai, D, Dreval, M, Dudson, B, Dunne, M, Duval, B, Eich, T, Elmore, S, Embreus, O, Esposito, B, Faitsch, M, Farnik, M, Fasoli, A, Fedorczak, N, Felici, F, Feng, S, Feng, X, Ferro, G, Fevrier, O, Ficker, O, Fil, A, Fontana, M, Frassinetti, L, Furno, I, Gahle, D, Galassi, D, Galazka, K, Gallo, A, Galperti, C, Garavaglia, S, Garcia, J, Garcia-Munoz, M, Garrido, A, Garrido, I, Gath, J, Geiger, B, Giruzzi, G, Gobbin, M, Goodman, T, Gorini, G, Gospodarczyk, M, Granucci, G, Graves, J, Gruca, M, Gyergyek, T, Hakola, A, Happel, T, Harrer, G, Harrison, J, Havlickova, E, Hawke, J, Henderson, S, Hennequin, P, Hesslow, L, Hogeweij, D, Hogge, J, Hopf, C, Hoppe, M, Horacek, J, Huang, Z, Hubbard, A, Iantchenko, A, Igochine, V, Innocente, P, Ionita Schrittwieser, C, Isliker, H, Jacquier, R, Jardin, A, Kappatou, A, Karpushov, A, Kazantzidis, P, Keeling, D, Kirneva, N, Komm, M, Kong, M, Kovacic, J, Krawczyk, N, Kudlacek, O, Kurki-Suonio, T, Kwiatkowski, R, Labit, B, Lazzaro, E, Linehan, B, Lipschultz, B, Llobet, X, Lombroni, R, Loschiavo, V, Lunt, T, Macusova, E, Madsen, J, Maljaars, E, Mantica, P, Maraschek, M, Marchetto, C, Marco, A, Mariani, A, Marini, C, Martin, Y, Matos, F, Frisina, M, Mavkov, B, Mazon, D, Mccarthy, P, Mcdermott, R, Menkovski, V, Merle, A, Meyer, H, Micheletti, D, Militello, F, Mitosinkova, K, Mlynar, J, Moiseenko, V, Molina Cabrera, P, Morales, J, Moret, J, Moro, A, Mumgaard, R, Naulin, V, Nem, R, Nespoli, F, Nielsen, A, Nielsen, S, Nocente, M, Nowak, S, Offeddu, N, Orsitto, F, Paccagnella, R, Palha, A, Papp, G, Pau, A, Pavlichenko, R, Perek, A, Pericoli Ridolfini, V, Pesamosca, F, Piergotti, V, Pigatto, L, Piovesan, P, Piron, C, Plyusnin, V, Poli, E, Porte, L, Pucella, G, Puiatti, M, Putterich, T, Rabinski, M, Juul Rasmussen, J, Ravensbergen, T, Reich, M, Reimerdes, H, Reimold, F, Reux, C, Ricci, D, Ricci, P, Rispoli, N, Rosato, J, Saarelma, S, Salewski, M, Salmi, A, Sauter, O, Scheffer, M, Schlatter, C, Schneider, B, Schrittwieser, R, Sharapov, S, Sheeba, R, Sheikh, U, Shousha, R, Silva, M, Sinha, J, Sozzi, C, Spolaore, M, Stipani, L, Strand, P, Tala, T, Tema Biwole, A, Teplukhina, A, Testa, D, Theiler, C, Thornton, A, Tomaz, G, Tomes, M, Tran, M, Tsironis, C, Tsui, C, Urban, J, Valisa, M, Vallar, M, Van Vugt, D, Vartanian, S, Vasilovici, O, Verhaegh, K, Vermare, L, Vianello, N, Viezzer, E, Vijvers, W, Villone, F, Voitsekhovitch, I, Vu, N, Walkden, N, Wauters, T, Weiland, M, Weisen, H, Wensing, M, Wiesenberger, M, Wilkie, G, Wischmeier, M, Wu, K, Yoshida, M, Zagorski, R, Zanca, P, Zebrowski, J, Zisis, A, Zuin, M, Coda S., Agostini M., Albanese R., Alberti S., Alessi E., Allan S., Allcock J., Ambrosino R., Anand H., Andrebe Y., Arnichand H., Auriemma F., Ayllon-Guerola J. M., Bagnato F., Ball J., Baquero-Ruiz M., Beletskii A. A., Bernert M., Bin W., Blanchard P., Blanken T. C., Boedo J. A., Bogar O., Bolzonella T., Bombarda F., Bonanomi N., Bouquey F., Bowman C., Brida D., Bucalossi J., Buermans J., Bufferand H., Buratti P., Calabro G., Calacci L., Camenen Y., Carnevale D., Carpanese F., Carr M., Carraro L., Casolari A., Causa F., Cerovsky J., Chellai O., Chmielewski P., Choi D., Christen N., Ciraolo G., Cordaro L., Costea S., Cruz N., Czarnecka A., Dal Molin A., David P., Decker J., De Oliveira H., Douai D., Dreval M. B., Dudson B., Dunne M., Duval B. P., Eich T., Elmore S., Embreus O., Esposito B., Faitsch M., Farnik M., Fasoli A., Fedorczak N., Felici F., Feng S., Feng X., Ferro G., Fevrier O., Ficker O., Fil A., Fontana M., Frassinetti L., Furno I., Gahle D. S., Galassi D., Galazka K., Gallo A., Galperti C., Garavaglia S., Garcia J., Garcia-Munoz M., Garrido A. J., Garrido I., Gath J., Geiger B., Giruzzi G., Gobbin M., Goodman T. P., Gorini G., Gospodarczyk M., Granucci G., Graves J. P., Gruca M., Gyergyek T., Hakola A., Happel T., Harrer G. F., Harrison J., Havlickova E., Hawke J., Henderson S., Hennequin P., Hesslow L., Hogeweij D., Hogge J. -P., Hopf C., Hoppe M., Horacek J., Huang Z., Hubbard A., Iantchenko A., Igochine V., Innocente P., Ionita Schrittwieser C., Isliker H., Jacquier R., Jardin A., Kappatou A., Karpushov A., Kazantzidis P. -V., Keeling D., Kirneva N., Komm M., Kong M., Kovacic J., Krawczyk N., Kudlacek O., Kurki-Suonio T., Kwiatkowski R., Labit B., Lazzaro E., Linehan B., Lipschultz B., Llobet X., Lombroni R., Loschiavo V. P., Lunt T., Macusova E., Madsen J., Maljaars E., Mantica P., Maraschek M., Marchetto C., Marco A., Mariani A., Marini C., Martin Y., Matos F., FRISINA, MAURIZIO REMO DOMENICO, Mavkov B., Mazon D., McCarthy P., McDermott R., Menkovski V., Merle A., Meyer H., Micheletti D., Militello F., Mitosinkova K., Mlynar J., Moiseenko V., Molina Cabrera P. A., Morales J., Moret J. -M., Moro A., Mumgaard R. T., Naulin V., Nem R. D., Nespoli F., Nielsen A. H., Nielsen S. K., Nocente M., Nowak S., Offeddu N., Orsitto F. P., Paccagnella R., Palha A., Papp G., Pau A., Pavlichenko R. O., Perek A., Pericoli Ridolfini V., Pesamosca F., Piergotti V., Pigatto L., Piovesan P., Piron C., Plyusnin V., Poli E., Porte L., Pucella G., Puiatti M. E., Putterich T., Rabinski M., Juul Rasmussen J., Ravensbergen T., Reich M., Reimerdes H., Reimold F., Reux C., Ricci D., Ricci P., Rispoli N., Rosato J., Saarelma S., Salewski M., Salmi A., Sauter O., Scheffer M., Schlatter C., Schneider B. S., Schrittwieser R., Sharapov S., Sheeba R. R., Sheikh U., Shousha R., SILVA, MARTA, Sinha J., Sozzi C., Spolaore M., Stipani L., Strand P., Tala T., Tema Biwole A. S., Teplukhina A. A., Testa D., Theiler C., Thornton A., Tomaz G., Tomes M., Tran M. Q., Tsironis C., Tsui C. K., Urban J., Valisa M., Vallar M., Van Vugt D., Vartanian S., Vasilovici O., Verhaegh K., Vermare L., Vianello N., Viezzer E., Vijvers W. A. J., Villone F., Voitsekhovitch I., Vu N. M. T., Walkden N., Wauters T., Weiland M., Weisen H., Wensing M., Wiesenberger M., Wilkie G., Wischmeier M., Wu K., Yoshida M., Zagorski R., Zanca P., Zebrowski J., Zisis A., Zuin M., Coda, S, Agostini, M, Albanese, R, Alberti, S, Alessi, E, Allan, S, Allcock, J, Ambrosino, R, Anand, H, Andrebe, Y, Arnichand, H, Auriemma, F, Ayllon-Guerola, J, Bagnato, F, Ball, J, Baquero-Ruiz, M, Beletskii, A, Bernert, M, Bin, W, Blanchard, P, Blanken, T, Boedo, J, Bogar, O, Bolzonella, T, Bombarda, F, Bonanomi, N, Bouquey, F, Bowman, C, Brida, D, Bucalossi, J, Buermans, J, Bufferand, H, Buratti, P, Calabro, G, Calacci, L, Camenen, Y, Carnevale, D, Carpanese, F, Carr, M, Carraro, L, Casolari, A, Causa, F, Cerovsky, J, Chellai, O, Chmielewski, P, Choi, D, Christen, N, Ciraolo, G, Cordaro, L, Costea, S, Cruz, N, Czarnecka, A, Dal Molin, A, David, P, Decker, J, De Oliveira, H, Douai, D, Dreval, M, Dudson, B, Dunne, M, Duval, B, Eich, T, Elmore, S, Embreus, O, Esposito, B, Faitsch, M, Farnik, M, Fasoli, A, Fedorczak, N, Felici, F, Feng, S, Feng, X, Ferro, G, Fevrier, O, Ficker, O, Fil, A, Fontana, M, Frassinetti, L, Furno, I, Gahle, D, Galassi, D, Galazka, K, Gallo, A, Galperti, C, Garavaglia, S, Garcia, J, Garcia-Munoz, M, Garrido, A, Garrido, I, Gath, J, Geiger, B, Giruzzi, G, Gobbin, M, Goodman, T, Gorini, G, Gospodarczyk, M, Granucci, G, Graves, J, Gruca, M, Gyergyek, T, Hakola, A, Happel, T, Harrer, G, Harrison, J, Havlickova, E, Hawke, J, Henderson, S, Hennequin, P, Hesslow, L, Hogeweij, D, Hogge, J, Hopf, C, Hoppe, M, Horacek, J, Huang, Z, Hubbard, A, Iantchenko, A, Igochine, V, Innocente, P, Ionita Schrittwieser, C, Isliker, H, Jacquier, R, Jardin, A, Kappatou, A, Karpushov, A, Kazantzidis, P, Keeling, D, Kirneva, N, Komm, M, Kong, M, Kovacic, J, Krawczyk, N, Kudlacek, O, Kurki-Suonio, T, Kwiatkowski, R, Labit, B, Lazzaro, E, Linehan, B, Lipschultz, B, Llobet, X, Lombroni, R, Loschiavo, V, Lunt, T, Macusova, E, Madsen, J, Maljaars, E, Mantica, P, Maraschek, M, Marchetto, C, Marco, A, Mariani, A, Marini, C, Martin, Y, Matos, F, Frisina, M, Mavkov, B, Mazon, D, Mccarthy, P, Mcdermott, R, Menkovski, V, Merle, A, Meyer, H, Micheletti, D, Militello, F, Mitosinkova, K, Mlynar, J, Moiseenko, V, Molina Cabrera, P, Morales, J, Moret, J, Moro, A, Mumgaard, R, Naulin, V, Nem, R, Nespoli, F, Nielsen, A, Nielsen, S, Nocente, M, Nowak, S, Offeddu, N, Orsitto, F, Paccagnella, R, Palha, A, Papp, G, Pau, A, Pavlichenko, R, Perek, A, Pericoli Ridolfini, V, Pesamosca, F, Piergotti, V, Pigatto, L, Piovesan, P, Piron, C, Plyusnin, V, Poli, E, Porte, L, Pucella, G, Puiatti, M, Putterich, T, Rabinski, M, Juul Rasmussen, J, Ravensbergen, T, Reich, M, Reimerdes, H, Reimold, F, Reux, C, Ricci, D, Ricci, P, Rispoli, N, Rosato, J, Saarelma, S, Salewski, M, Salmi, A, Sauter, O, Scheffer, M, Schlatter, C, Schneider, B, Schrittwieser, R, Sharapov, S, Sheeba, R, Sheikh, U, Shousha, R, Silva, M, Sinha, J, Sozzi, C, Spolaore, M, Stipani, L, Strand, P, Tala, T, Tema Biwole, A, Teplukhina, A, Testa, D, Theiler, C, Thornton, A, Tomaz, G, Tomes, M, Tran, M, Tsironis, C, Tsui, C, Urban, J, Valisa, M, Vallar, M, Van Vugt, D, Vartanian, S, Vasilovici, O, Verhaegh, K, Vermare, L, Vianello, N, Viezzer, E, Vijvers, W, Villone, F, Voitsekhovitch, I, Vu, N, Walkden, N, Wauters, T, Weiland, M, Weisen, H, Wensing, M, Wiesenberger, M, Wilkie, G, Wischmeier, M, Wu, K, Yoshida, M, Zagorski, R, Zanca, P, Zebrowski, J, Zisis, A, Zuin, M, Coda S., Agostini M., Albanese R., Alberti S., Alessi E., Allan S., Allcock J., Ambrosino R., Anand H., Andrebe Y., Arnichand H., Auriemma F., Ayllon-Guerola J. M., Bagnato F., Ball J., Baquero-Ruiz M., Beletskii A. A., Bernert M., Bin W., Blanchard P., Blanken T. C., Boedo J. A., Bogar O., Bolzonella T., Bombarda F., Bonanomi N., Bouquey F., Bowman C., Brida D., Bucalossi J., Buermans J., Bufferand H., Buratti P., Calabro G., Calacci L., Camenen Y., Carnevale D., Carpanese F., Carr M., Carraro L., Casolari A., Causa F., Cerovsky J., Chellai O., Chmielewski P., Choi D., Christen N., Ciraolo G., Cordaro L., Costea S., Cruz N., Czarnecka A., Dal Molin A., David P., Decker J., De Oliveira H., Douai D., Dreval M. B., Dudson B., Dunne M., Duval B. P., Eich T., Elmore S., Embreus O., Esposito B., Faitsch M., Farnik M., Fasoli A., Fedorczak N., Felici F., Feng S., Feng X., Ferro G., Fevrier O., Ficker O., Fil A., Fontana M., Frassinetti L., Furno I., Gahle D. S., Galassi D., Galazka K., Gallo A., Galperti C., Garavaglia S., Garcia J., Garcia-Munoz M., Garrido A. J., Garrido I., Gath J., Geiger B., Giruzzi G., Gobbin M., Goodman T. P., Gorini G., Gospodarczyk M., Granucci G., Graves J. P., Gruca M., Gyergyek T., Hakola A., Happel T., Harrer G. F., Harrison J., Havlickova E., Hawke J., Henderson S., Hennequin P., Hesslow L., Hogeweij D., Hogge J. -P., Hopf C., Hoppe M., Horacek J., Huang Z., Hubbard A., Iantchenko A., Igochine V., Innocente P., Ionita Schrittwieser C., Isliker H., Jacquier R., Jardin A., Kappatou A., Karpushov A., Kazantzidis P. -V., Keeling D., Kirneva N., Komm M., Kong M., Kovacic J., Krawczyk N., Kudlacek O., Kurki-Suonio T., Kwiatkowski R., Labit B., Lazzaro E., Linehan B., Lipschultz B., Llobet X., Lombroni R., Loschiavo V. P., Lunt T., Macusova E., Madsen J., Maljaars E., Mantica P., Maraschek M., Marchetto C., Marco A., Mariani A., Marini C., Martin Y., Matos F., FRISINA, MAURIZIO REMO DOMENICO, Mavkov B., Mazon D., McCarthy P., McDermott R., Menkovski V., Merle A., Meyer H., Micheletti D., Militello F., Mitosinkova K., Mlynar J., Moiseenko V., Molina Cabrera P. A., Morales J., Moret J. -M., Moro A., Mumgaard R. T., Naulin V., Nem R. D., Nespoli F., Nielsen A. H., Nielsen S. K., Nocente M., Nowak S., Offeddu N., Orsitto F. P., Paccagnella R., Palha A., Papp G., Pau A., Pavlichenko R. O., Perek A., Pericoli Ridolfini V., Pesamosca F., Piergotti V., Pigatto L., Piovesan P., Piron C., Plyusnin V., Poli E., Porte L., Pucella G., Puiatti M. E., Putterich T., Rabinski M., Juul Rasmussen J., Ravensbergen T., Reich M., Reimerdes H., Reimold F., Reux C., Ricci D., Ricci P., Rispoli N., Rosato J., Saarelma S., Salewski M., Salmi A., Sauter O., Scheffer M., Schlatter C., Schneider B. S., Schrittwieser R., Sharapov S., Sheeba R. R., Sheikh U., Shousha R., SILVA, MARTA, Sinha J., Sozzi C., Spolaore M., Stipani L., Strand P., Tala T., Tema Biwole A. S., Teplukhina A. A., Testa D., Theiler C., Thornton A., Tomaz G., Tomes M., Tran M. Q., Tsironis C., Tsui C. K., Urban J., Valisa M., Vallar M., Van Vugt D., Vartanian S., Vasilovici O., Verhaegh K., Vermare L., Vianello N., Viezzer E., Vijvers W. A. J., Villone F., Voitsekhovitch I., Vu N. M. T., Walkden N., Wauters T., Weiland M., Weisen H., Wensing M., Wiesenberger M., Wilkie G., Wischmeier M., Wu K., Yoshida M., Zagorski R., Zanca P., Zebrowski J., Zisis A., and Zuin M.

Abstract

The research program of the TCV tokamak ranges from conventional to advanced-tokamak scenarios and alternative divertor configurations, to exploratory plasmas driven by theoretical insight, exploiting the device's unique shaping capabilities. Disruption avoidance by real-time locked mode prevention or unlocking with electron-cyclotron resonance heating (ECRH) was thoroughly documented, using magnetic and radiation triggers. Runaway generation with high-Z noble-gas injection and runaway dissipation by subsequent Ne or Ar injection were studied for model validation. The new 1 MW neutral beam injector has expanded the parameter range, now encompassing ELMy H-modes in an ITER-like shape and nearly noninductive II-mode discharges sustained by electron cyclotron and neutral beam current drive. In the H-mode, the pedestal pressure increases modestly with nitrogen seeding while fueling moves the density pedestal outwards, but the plasma stored energy is largely uncorrelated to either seeding or fueling. High fueling at high triangularity is key to accessing the attractive small edge-localized mode (type-II) regime. Turbulence is reduced in the core at negative triangularity, consistent with increased confinement and in accord with global gyrokinetic simulations. The geodesic acoustic mode, possibly coupled with avalanche events, has been linked with particle flow to the wall in diverted plasmas. Detachment, scrape-off layer transport, and turbulence were studied in L- and H-modes in both standard and alternative configurations (snowflake, super-X, and beyond). The detachment process is caused by power `starvation' reducing the ionization source, with volume recombination playing only a minor role. Partial detachment in the H-mode is obtained with impurity seeding and has shown little dependence on flux expansion in standard single-null geometry. In the attached 1,-mode phase, increasing the outer connection length reduces the in-out heat-flow asymmetry. A doublet plasma, fe

Published
2019

7. Bridging the age gap: observational cohort study of effects of chemotherapy and trastuzumab on recurrence, survival and quality of life in older women with early breast cancer

Author

Ring, A., Battisti, N.M.L., Reed, M.W.R., Herbert, E., Morgan, J.L., Bradburn, M., Walters, S.J., Collins, K.A., Ward, S.E., Holmes, G.R., Burton, Maria, Lifford, K., Edwards, A., Robinson, T.G., Martin, C., Chater, T., Pemberton, K.J., Brennan, A., Cheung, K.L., Todd, A., Audisio, R.A., Wright, J., Simcock, R., Green, T., Revell, D., Gath, J., Horgan, K., Holcombe, C., Winter, M.C., Naik, J., Parmeshwar, R., Gosney, M.A., Hatton, M.Q., Thompson, A.M., Wyld, L., Collins, K., Ward, S., Holmes, G., Morgan, J., Walters, S., Burton, M., Brain, K., Robinson, T., Pemberton, K., Shrestha, A., Nettleship, A., Richards, P., Harder, H., Audisio, R., Murray, C., Thomson, A.M., Gosney, M., Hatton, M., Armitage, F., Patnick, J., Revill, D., and Winter, M.

Subjects
Oncology, Bridged-Ring Compounds, medicine.medical_specialty, Cancer Research, medicine.medical_treatment, Breast Neoplasms, Article, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Quality of life, Drug Therapy, Trastuzumab, Internal medicine, medicine, Chemotherapy, Humans, Anthracyclines, 030212 general & internal medicine, Prospective Studies, Stage (cooking), Propensity Score, Aged, Aged, 80 and over, business.industry, Hazard ratio, Cancer, medicine.disease, Survival Analysis, Treatment Outcome, Patient Satisfaction, 030220 oncology & carcinogenesis, Quality of Life, Observational study, Female, Taxoids, business, medicine.drug, Cohort study
Abstract

Background Chemotherapy improves outcomes for high risk early breast cancer (EBC) patients but is infrequently offered to older individuals. This study determined if there are fit older patients with high-risk disease who may benefit from chemotherapy. Methods A multicentre, prospective, observational study was performed to determine chemotherapy (±trastuzumab) usage and survival and quality-of-life outcomes in EBC patients aged ≥70 years. Propensity score-matching adjusted for variation in baseline age, fitness and tumour stage. Results Three thousands four hundred sixteen women were recruited from 56 UK centres between 2013 and 2018. Two thousands eight hundred eleven (82%) had surgery. 1520/2811 (54%) had high-risk EBC and 2059/2811 (73%) were fit. Chemotherapy was given to 306/1100 (27.8%) fit patients with high-risk EBC. Unmatched comparison of chemotherapy versus no chemotherapy demonstrated reduced metastatic recurrence risk in high-risk patients(hazard ratio [HR] 0.36 [95% CI 0.19–0.68]) and in 541 age, stage and fitness-matched patients(adjusted HR 0.43 [95% CI 0.20–0.92]) but no benefit to overall survival (OS) or breast cancer-specific survival (BCSS) in either group. Chemotherapy improved survival in women with oestrogen receptor (ER)-negative cancer (OS: HR 0.20 [95% CI 0.08–0.49];BCSS: HR 0.12 [95% CI 0.03–0.44]).Transient negative quality-of-life impacts were observed. Conclusions Chemotherapy was associated with reduced risk of metastatic recurrence, but survival benefits were only seen in patients with ER-negative cancer. Quality-of-life impacts were significant but transient. Trial Registration ISRCTN 46099296

Published
2021

8. Bridging the age gap in breast cancer: cluster randomized trial of the effects of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices

Author

Wyld, L., Reed, M.W.R., Collins, K., Burton, M., Lifford, K., Edwards, A., Ward, S., Holmes, G., Morgan, J., Bradburn, M., Walters, S.J., Ring, A., Robinson, T.G., Martin, C., Chater, T., Pemberton, K., Shrestha, A., Nettleship, A., Murray, C., Brown, M., Richards, P., Cheung, K.L., Todd, A., Harder, H., Brain, K., Audisio, R.A., Wright, J., Simcock, R., Armitage, F., Bursnall, M., Green, T., Revell, D., Gath, J., Horgan, K., Holcombe, C., Winter, M., Naik, J., Parmeshwar, R., Gosney, M., Hatton, M., and Thompson, A.M.

Subjects
Surgery
Abstract

Background\ud \ud Rates of surgery and adjuvant therapy for breast cancer vary widely between breast units. This may contribute to differences in survival. This cluster RCT evaluated the impact of decision support interventions (DESIs) for older women with breast cancer, to ascertain whether DESIs influenced quality of life, survival, decision quality, and treatment choice.\ud \ud \ud Methods\ud \ud A multicentre cluster RCT compared the use of two DESIs against usual care in treatment decision-making in older women (aged at least ≥70 years) with breast cancer. Each DESI comprised an online algorithm, booklet, and brief decision aid to inform choices between surgery plus adjuvant endocrine therapy versus primary endocrine therapy, and adjuvant chemotherapy versus no chemotherapy. The primary outcome was quality of life. Secondary outcomes included decision quality measures, survival, and treatment choice.\ud \ud \ud Results\ud \ud A total of 46 breast units were randomized (21 intervention, 25 usual care), recruiting 1339 women (670 intervention, 669 usual care). There was no significant difference in global quality of life at 6 months after the baseline assessment on intention-to-treat analysis (difference –0.20, 95 per cent confidence interval (C.I.) –2.69 to 2.29; P = 0.900). In women offered a choice of primary endocrine therapy versus surgery plus endocrine therapy, knowledge about treatments was greater in the intervention arm (94 versus 74 per cent; P = 0.003). Treatment choice was altered, with a primary endocrine therapy rate among women with oestrogen receptor-positive disease of 21.0 per cent in the intervention versus 15.4 per cent in usual-care sites (difference 5.5 (95 per cent C.I. 1.1 to 10.0) per cent; P = 0.029). The chemotherapy rate was 10.3 per cent at intervention versus 14.8 per cent at usual-care sites (difference –4.5 (C.I. –8.0 to 0) per cent; P = 0.013). Survival was similar in both arms.\ud \ud \ud Conclusion\ud \ud The use of DESIs in older women increases knowledge of breast cancer treatment options, facilitates shared decision-making, and alters treatment selection.\ud \ud \ud Trial registration numbers: EudraCT 2015-004220-61 (https://eudract.ema.europa.eu/), ISRCTN46099296 (http://www.controlled-trials.com).

Published
2021

9. Observational cohort study to determine the degree and causes of variation in the rate of surgery or primary endocrine therapy in older women with operable breast cancer

Author

Morgan, J.L., Holmes, G., Ward, S., Martin, C., Burton, M., Walters, S.J., Cheung, K.L., Audisio, R.A., Reed, M.W.R., Wyld, L., Collins, K., Lifford, K., Edwards, A., Brain, K., Ring, A., Robinson, T., Chater, T., Pemberton, K., Shrestha, A., Nettleship, A., Richards, P., Todd, A., Harder, H., Wright, J., Simcock, R., Murray, C., Green, T., Revill, D., Gath, J., Horgan, K., Holcombe, C., Naik, J., and Parmeshwar, R.

Abstract

Background\ud \ud In the UK there is variation in the treatment of older women with breast cancer, with up to 40% receiving primary endocrine therapy (PET), which is associated with inferior survival. Case mix and patient choice may explain some variation in practice but clinician preference may also be important.\ud \ud \ud \ud Methods\ud \ud A multicentre prospective cohort study of women aged >70 with operable breast cancer. Patient characteristics (health status, age, tumour characteristics, treatment allocation and decision-making preference) were analysed to identify whether treatment variation persisted following case-mix adjustment. Expected case-mix adjusted surgery rates were derived by logistic regression using the variables age, co-morbidity, tumour stage and grade. Concordance between patients’ preferred and actual decision-making style was assessed and associations between age, treatment and decision-making style calculated.\ud \ud \ud \ud Results\ud \ud Women (median age 77, range 70–102) were recruited from 56 UK breast units between 2013 and 2018. Of 2854/3369 eligible women with oestrogen receptor positive breast cancer, 2354 were treated with surgery and 500 with PET. Unadjusted surgery rates varied between hospitals, with 23/56 units falling outside the 95% confidence intervals on funnel plots. Adjusting for case mix reduced, but did not eliminate, this variation between hospitals (10/56 units had practice outside the 95% confidence intervals). Patients treated with PET had more patient-centred decisions compared to surgical patients (42.2% vs 28.4%, p

Published
2021

11. Bridging the age gap in breast cancer: cluster randomized trial of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices

Author

Wyld, L, primary, Reed, M W R, additional, Collins, K, additional, Burton, M, additional, Lifford, K, additional, Edwards, A, additional, Ward, S, additional, Holmes, G, additional, Morgan, J, additional, Bradburn, M, additional, Walters, S J, additional, Ring, A, additional, Robinson, T G, additional, Martin, C, additional, Chater, T, additional, Pemberton, K, additional, Shrestha, A, additional, Nettleship, A, additional, Murray, C, additional, Brown, M, additional, Richards, P, additional, Cheung, K L, additional, Todd, A, additional, Harder, H, additional, Brain, K, additional, Audisio, R A, additional, Wright, J, additional, Simcock, R, additional, Armitage, F, additional, Bursnall, M, additional, Green, T, additional, Revell, D, additional, Gath, J, additional, Horgan, K, additional, Holcombe, C, additional, Winter, M, additional, Naik, J, additional, Parmeshwar, R, additional, Gosney, M, additional, Hatton, M, additional, and Thompson, A M, additional

Published
2021
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12. Bridging the age gap in breast cancer: impact of omission of breast cancer surgery in older women with oestrogen receptor-positive early breast cancer on quality-of-life outcomes

Author

Morgan, J L, primary, Shrestha, A, additional, Reed, M W R, additional, Herbert, E, additional, Bradburn, M, additional, Walters, S J, additional, Martin, C, additional, Collins, K, additional, Ward, S, additional, Holmes, G, additional, Burton, M, additional, Lifford, K, additional, Edwards, A, additional, Ring, A, additional, Robinson, T, additional, Chater, T, additional, Pemberton, K, additional, Brennan, A, additional, Cheung, K L, additional, Todd, A, additional, Audisio, R, additional, Wright, J, additional, Simcock, R, additional, Thomson, A M, additional, Gosney, M, additional, Hatton, M, additional, Green, T, additional, Revill, D, additional, Gath, J, additional, Horgan, K, additional, Holcombe, C, additional, Winter, M C, additional, Naik, J, additional, Parmeschwar, R, additional, and Wyld, L, additional

Published
2021
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15. Beta-endorphin amyloid fibril

Author

Verasdonck, J., primary, Seuring, C., additional, Gath, J., additional, Ghosh, D., additional, Nespovitaya, N., additional, Waelti, M.A., additional, Maji, S., additional, Cadalbert, R., additional, Boeckmann, A., additional, Guentert, P., additional, Meier, B.H., additional, and Riek, R., additional

Published
2020
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16. Physics research on the TCV tokamak facility: from conventional to alternative scenarios and beyond

Author

Coda, S., Agostini, M., Albanese, R., Alberti, S., Alessi, E., Allan, S., Allcock, J., Ambrosino, R., Anand, H., Andrebe, Y., Arnichand, H., Auriemma, F., Ayllon-Guerola, J. M., Bagnato, F., Ball, J., Baquero-Ruiz, M., Beletskii, A. A., Bernert, M., Bin, W., Blanchard, P., Blanken, T.C., Boedo, J.A., Bogar, O., Bolzonella, T., Bombarda, F., Bonanomi, N., Bouquey, F., Bowman, C., Brida, D., Bucalossi, J., Buermans, J., Bufferand, H., Buratti, P., Calabró, G., Calacci, L., Camenen, Y., Carnevale, D., Carpanese, F., Carr, M., Carraro, L., Casolari, A., Causa, F., Čeřovský, J., Chellaï, O., Chmielewski, P., Choi, D., Christen, N., Ciraolo, G., Cordaro, L., Costea, S., Cruz, N., Czarnecka, A., Dal Molin, A., David, P., Decker, J., De Oliveira, H., Douai, D., Dreval, M. B., Dudson, B., Dunne, M., Duval, B. P., Eich, T., Elmore, S., Embréus, O., Esposito, B., Faitsch, M., Farnik, M., Fasoli, A., Fedorczak, N., Felici, F., Feng, S., Feng, X., Ferró, G., Février, O., Ficker, O., Fil, A., Fontana, M., Frassinetti, L., Furno, I., Gahle, D.S., Galassi, D., Gałazka, K., Gallo, A., Galperti, C., Garavaglia, S., Garcia, J., Garcia-Munoz, M., Garrido, A.J., Garrido, I., Gath, J., Geiger, B., Giruzzi, G., Gobbin, M., Goodman, T.P., Gorini, G., Gospodarczyk, M., Granucci, G., Graves, J.P., Gruca, M., Gyergyek, T., Hakola, A., Happel, T., Harrer, G.F., Harrison, J., Havličková, E., Hawke, J., Henderson, S., Hennequin, P., Hesslow, L., Hogeweij, D., Hogge, J.Ph., Hopf, C., Hoppe, M., Horáček, J., Huang, Z., Hubbard, A., Iantchenko, A., Igochine, V., Innocente, P., Ionita Schrittwieser, C., Isliker, H., Jacquier, R., Jardin, A., Kappatou, A., Karpushov, A., Kazantzidis, P.V., Keeling, D., Kirneva, N., Komm, M., Kong, M., Kovacic, J., Krawczyk, N., Kudlacek, O., Kurki-Suonio, T., Kwiatkowski, R., Labit, B., Lazzaro, E., Linehan, B., Lipschultz, B., Llobet, X., Lombroni, R., Loschiavo, V.P., Lunt, T., Macusova, E., Madsen, J., Maljaars, E., Mantica, P., Maraschek, M., Marchetto, C., Marco, A., Mariani, A., Marini, C., Martin, Y., Matos, F., Maurizio, R., Mavkov, B., Mazon, D., McCarthy, P., McDermott, R., Menkovski, V., Merle, A., Meyer, H., Micheletti, D., Militello, F., Mitosinkova, K., Mlynář, J., Moiseenko, V., Molina Cabrera, P.A., Morales, J., Moret, J.M., Moro, A., Mumgaard, R.T., Naulin, V., Nem, R.D., Nespoli, F., Nielsen, A.H., Nielsen, S.K., Nocente, M., Nowak, S., Offeddu, N., Orsitto, F.P., Paccagnella, R., Palha, A., Papp, G., Pau, A., Pavlichenko, R.O., Perek, A., Pericoli Ridolfini, V., Pesamosca, F., Piergotti, V., Pigatto, L., Piovesan, P., Piron, C., Plyusnin, V., Poli, E., Porte, L., Pucella, G., Puiatti, M.E., Pütterich, T., Rabinski, M., Juul Rasmussen, J., Ravensbergen, T., Reich, M., Reimerdes, H., Reimold, F., Reux, C., Ricci, D., Ricci, P., Rispoli, N., Rosato, J., Saarelma, S., Salewski, M., Salmi, A., Sauter, O., Scheffer, M., Schlatter, Ch., Schneider, B.S., Schrittwieser, R., Sharapov, S., Sheeba, R. R., Sheikh, U., Shousha, R., Silva, M., Sinha, J., Sozzi, C., Spolaore, M., Stipani, L., Strand, P., Tala, T., Tema Biwole, A.S., Teplukhina, A. A., Testa, D., Theiler, C., Thornton, A., Tomaž, G., Tomes, M., Tran, M.Q., Tsironis, C., Tsui, C.K., Urban, J., Valisa, M., Vallar, M., van Vugt, D., Vartanian, S., Vasilovici, O., Verhaegh, K., Vermare, L., Vianello, N., Viezzer, E., Vijvers, W.A.J., Villone, F., Voitsekhovitch, I., Vu, N.M.T., Walkden, N., Wauters, T., Weiland, M., Weisen, H., Wensing, M., Wiesenberger, M., Wilkie, G., Wischmeier, M., Wu, K., Yoshida, M., Zagorski, R., Zanca, P., Zebrowski, J., Zisis, A., Zuin, M., Coda, S., Agostini, M., Albanese, R., Alberti, S., Alessi, E., Allan, S., Allcock, J., Ambrosino, R., Anand, H., Andrebe, Y., Arnichand, H., Auriemma, F., Ayllon-Guerola, J. M., Bagnato, F., Ball, J., Baquero-Ruiz, M., Beletskii, A. A., Bernert, M., Bin, W., Blanchard, P., Blanken, T.C., Boedo, J.A., Bogar, O., Bolzonella, T., Bombarda, F., Bonanomi, N., Bouquey, F., Bowman, C., Brida, D., Bucalossi, J., Buermans, J., Bufferand, H., Buratti, P., Calabró, G., Calacci, L., Camenen, Y., Carnevale, D., Carpanese, F., Carr, M., Carraro, L., Casolari, A., Causa, F., Čeřovský, J., Chellaï, O., Chmielewski, P., Choi, D., Christen, N., Ciraolo, G., Cordaro, L., Costea, S., Cruz, N., Czarnecka, A., Dal Molin, A., David, P., Decker, J., De Oliveira, H., Douai, D., Dreval, M. B., Dudson, B., Dunne, M., Duval, B. P., Eich, T., Elmore, S., Embréus, O., Esposito, B., Faitsch, M., Farnik, M., Fasoli, A., Fedorczak, N., Felici, F., Feng, S., Feng, X., Ferró, G., Février, O., Ficker, O., Fil, A., Fontana, M., Frassinetti, L., Furno, I., Gahle, D.S., Galassi, D., Gałazka, K., Gallo, A., Galperti, C., Garavaglia, S., Garcia, J., Garcia-Munoz, M., Garrido, A.J., Garrido, I., Gath, J., Geiger, B., Giruzzi, G., Gobbin, M., Goodman, T.P., Gorini, G., Gospodarczyk, M., Granucci, G., Graves, J.P., Gruca, M., Gyergyek, T., Hakola, A., Happel, T., Harrer, G.F., Harrison, J., Havličková, E., Hawke, J., Henderson, S., Hennequin, P., Hesslow, L., Hogeweij, D., Hogge, J.Ph., Hopf, C., Hoppe, M., Horáček, J., Huang, Z., Hubbard, A., Iantchenko, A., Igochine, V., Innocente, P., Ionita Schrittwieser, C., Isliker, H., Jacquier, R., Jardin, A., Kappatou, A., Karpushov, A., Kazantzidis, P.V., Keeling, D., Kirneva, N., Komm, M., Kong, M., Kovacic, J., Krawczyk, N., Kudlacek, O., Kurki-Suonio, T., Kwiatkowski, R., Labit, B., Lazzaro, E., Linehan, B., Lipschultz, B., Llobet, X., Lombroni, R., Loschiavo, V.P., Lunt, T., Macusova, E., Madsen, J., Maljaars, E., Mantica, P., Maraschek, M., Marchetto, C., Marco, A., Mariani, A., Marini, C., Martin, Y., Matos, F., Maurizio, R., Mavkov, B., Mazon, D., McCarthy, P., McDermott, R., Menkovski, V., Merle, A., Meyer, H., Micheletti, D., Militello, F., Mitosinkova, K., Mlynář, J., Moiseenko, V., Molina Cabrera, P.A., Morales, J., Moret, J.M., Moro, A., Mumgaard, R.T., Naulin, V., Nem, R.D., Nespoli, F., Nielsen, A.H., Nielsen, S.K., Nocente, M., Nowak, S., Offeddu, N., Orsitto, F.P., Paccagnella, R., Palha, A., Papp, G., Pau, A., Pavlichenko, R.O., Perek, A., Pericoli Ridolfini, V., Pesamosca, F., Piergotti, V., Pigatto, L., Piovesan, P., Piron, C., Plyusnin, V., Poli, E., Porte, L., Pucella, G., Puiatti, M.E., Pütterich, T., Rabinski, M., Juul Rasmussen, J., Ravensbergen, T., Reich, M., Reimerdes, H., Reimold, F., Reux, C., Ricci, D., Ricci, P., Rispoli, N., Rosato, J., Saarelma, S., Salewski, M., Salmi, A., Sauter, O., Scheffer, M., Schlatter, Ch., Schneider, B.S., Schrittwieser, R., Sharapov, S., Sheeba, R. R., Sheikh, U., Shousha, R., Silva, M., Sinha, J., Sozzi, C., Spolaore, M., Stipani, L., Strand, P., Tala, T., Tema Biwole, A.S., Teplukhina, A. A., Testa, D., Theiler, C., Thornton, A., Tomaž, G., Tomes, M., Tran, M.Q., Tsironis, C., Tsui, C.K., Urban, J., Valisa, M., Vallar, M., van Vugt, D., Vartanian, S., Vasilovici, O., Verhaegh, K., Vermare, L., Vianello, N., Viezzer, E., Vijvers, W.A.J., Villone, F., Voitsekhovitch, I., Vu, N.M.T., Walkden, N., Wauters, T., Weiland, M., Weisen, H., Wensing, M., Wiesenberger, M., Wilkie, G., Wischmeier, M., Wu, K., Yoshida, M., Zagorski, R., Zanca, P., Zebrowski, J., Zisis, A., and Zuin, M.

Abstract

The research program of the TCV tokamak ranges from conventional to advanced-tokamak scenarios and alternative divertor configurations, to exploratory plasmas driven by theoretical insight, exploiting the device's unique shaping capabilities. Disruption avoidance by real-time locked mode prevention or unlocking with electron-cyclotron resonance heating (ECRH) was thoroughly documented, using magnetic and radiation triggers. Runaway generation with high-Z noble-gas injection and runaway dissipation by subsequent Ne or Ar injection were studied for model validation. The new 1 MW neutral beam injector has expanded the parameter range, now encompassing ELMy H-modes in an ITER-like shape and nearly non-inductive H-mode discharges sustained by electron cyclotron and neutral beam current drive. In the H-mode, the pedestal pressure increases modestly with nitrogen seeding while fueling moves the density pedestal outwards, but the plasma stored energy is largely uncorrelated to either seeding or fueling. High fueling at high triangularity is key to accessing the attractive small edge-localized mode (type-II) regime. Turbulence is reduced in the core at negative triangularity, consistent with increased confinement and in accord with global gyrokinetic simulations. The geodesic acoustic mode, possibly coupled with avalanche events, has been linked with particle flow to the wall in diverted plasmas. Detachment, scrape-off layer transport, and turbulence were studied in L- and H-modes in both standard and alternative configurations (snowflake, super-X, and beyond). The detachment process is caused by power 'starvation' reducing the ionization source, with volume recombination playing only a minor role. Partial detachment in the H-mode is obtained with impurity seeding and has shown little dependence on flux expansion in standard single-null geometry. In the attached L-mode phase, increasing the outer connection length reduces the in-out heat-flow asymmetry. A doublet plasma

Published
2019

17. Physics research on the TCV tokamak facility: From conventional to alternative scenarios and beyond

Author

Swiss National Science Foundation, Coda, S., Agostini, Matteo, Albanese, R., Alberti, S., Alessi, E., Allan, S., Allcock, J., Ambrosino, R., Anand, H., Andrebe, Y., Arnichand, H., Gahle, D. S., Galassi, D., Pericoli Ridolfini, V., Gallo, A., Salmi, A., Calacci, L., Zagorski, R., Linehan, B., Harrer, G. F., Boedo, J. A., Vianello, N., Lipschultz, B., Llobet, X., Wilkie, G., Voitsekhovitch, I., Carraro, L., Lombroni, R., Granucci, G., Loschiavo, V. P., Lunt, T., Weiland, M., Viezzer, Eleonora, Chmielewski, P., Ball, J., Giruzzi, G., Macusova, E., Madsen, J., Hesslow, L., Zebrowski, J., Garrido, A. J., Maljaars, E., Mantica, P., Happel, T., Wischmeier, M., Galperti, C., Puiatti, M. E., Maraschek, M., Weisen, H., Reimold, F., Marchetto, C., Vu, N. M. T., Rosato, J., Marco, A., Vijvers, W. A. J., Scheffer, M., Mariani, A., Schrittwieser, R., Marini, C., Martin, Y., Baquero, M., Zisis, A., Hogeweij, D., Igochine, V., Kappatou, A., Kong, M., Matos, F., Maruzio, R., Mavkov, B., Sharapov, S. E., Schalatter, Ch., Saarelma, S., Reux, C., Pütterich, T., Mazon, D., McCarthy, P., Reimerdes, H., McDermott, R.M., Pucella, G., Menkovski, V., Hopf, C., Gruca, M., Merle, A., Buratti, P, Havlíčková, E., Meyer, H., Bouquey, F., Piergotti, V., Saelwski, M., Micheletti, D., Beletskii, A. A., Bufferand, H., Ricci, D., Garrido, I., Militello, F., Mitosinkova, K., Bonanomi, N., Rabinski, M., Ciraolo, G., Gobbin, M., Mlynář, J., Moiseenko, V., Wu, K., Molina Cabrera, P. A., Chellaï, Oulfa, Kazantzidis, P. V., Graves, J. P., Sheea, R. R., Pesamosca, F., Cordaro, L., Sheikh, U., Shousha, R., Goodman, T. P., Garavaglia, S., Kovacic, J., Silva, M., Offeddu, N., Sinha, J., Sozzi, C., Gath, J., Kwiatkowski, R., Hawke, J., Nespoli, F., Spolaore, M., Stipani, L., Poli, E., Gyergyek, T., Mumgaard, R. T., Bogar, O., Strand, P., Gorini, Giuseppe, Morales, J., Brida, D., Tala, T., Hubbard, A., Camenen, Y., Tema Biwole, A. S., García-Muñoz, M., Casolari, A., Teplukhina, A. A., Choi, D., Testa, D., Costea, S., Theiler, C., Thornton, A., Henderson, S., Iantchenko, A., Porte, L., Reich, M., Ricci, P., Tomaž, G., Tomes, M., Tran, M. Q., Cruz, N., Christen, N., Causa, F., Carnevale, D., Bucalossi, J., Bolzonella, T., Tsironis, C., Tsui, C. K., Bowman, C., Urban, J., Blanchard, P., Pavlinchenko, R. O., Valisa, M., Jardin, A., Pigatto, L., Vallar, M., Hakola, A., Čeřovský, J., Van Vugt, D., Hennequin, P., Ayllón Guerola, Juan Manuel, Carpanese , F., Naulin, V., Vartanian, S., Vasilovici, O., Geiger, B., Buermans, J., Nielsen, A. H., Verhaegh, K., Vermare, L., Gospodarczyk, M., Bombarda, T., Kurki-Suonio, T., Rispoli, N., Orsito, F. P., Czarnecka, A., Yoshida, M., Dal Molin, A., David, P., Nielsen, S. K., Moret, J. M., Sauter, O., Decker, J., Wensing, M., De Oliveira, H., Douai, D., Bernert, M., Piovesan, P., Walkden, N., Dreval, M. B., Hoppe, M., Zuin, M., Perek, A., Villone, F., Dudson, B., Dunne, M., Nocente, M., Ionita Schrittwieser, C., Duval, B. P., Nem, R. D., Keeling, D., Eich, T., Moro, A.M., Krawczyk, N., Elmore, S., Labit, B., Embréus, O., Esposito, B., Faitsch, M., Piron, C., Bin, W., EUROfusion MST1 Team, Calabró, G., Carr, M., Farník, M., Fasoli, M. A., Horáček, J., Lazzaro, E., Kudlacek, O., Kirneva, N., Isliker, H., Fedorczak, N., Felici, F., Feng, S., Innocente, P., Feng, X., Hogge, J. Ph., Ferró, G., Blanken, T. C., Zanka, P., Février, O., Ravensbergen, T., Bagnato, F., Ficker, O., Plyusnin, V., Harrison, J., Komm, M., Fil, A., Fontana, M., Rasmussen, Juul, Jacquier, R., Wauters, T., Frassinetti, L., Huang, Z., Nowak, S., Furno, I., Schneider, B. S., Wiesenberger, M., Swiss National Science Foundation, Coda, S., Agostini, Matteo, Albanese, R., Alberti, S., Alessi, E., Allan, S., Allcock, J., Ambrosino, R., Anand, H., Andrebe, Y., Arnichand, H., Gahle, D. S., Galassi, D., Pericoli Ridolfini, V., Gallo, A., Salmi, A., Calacci, L., Zagorski, R., Linehan, B., Harrer, G. F., Boedo, J. A., Vianello, N., Lipschultz, B., Llobet, X., Wilkie, G., Voitsekhovitch, I., Carraro, L., Lombroni, R., Granucci, G., Loschiavo, V. P., Lunt, T., Weiland, M., Viezzer, Eleonora, Chmielewski, P., Ball, J., Giruzzi, G., Macusova, E., Madsen, J., Hesslow, L., Zebrowski, J., Garrido, A. J., Maljaars, E., Mantica, P., Happel, T., Wischmeier, M., Galperti, C., Puiatti, M. E., Maraschek, M., Weisen, H., Reimold, F., Marchetto, C., Vu, N. M. T., Rosato, J., Marco, A., Vijvers, W. A. J., Scheffer, M., Mariani, A., Schrittwieser, R., Marini, C., Martin, Y., Baquero, M., Zisis, A., Hogeweij, D., Igochine, V., Kappatou, A., Kong, M., Matos, F., Maruzio, R., Mavkov, B., Sharapov, S. E., Schalatter, Ch., Saarelma, S., Reux, C., Pütterich, T., Mazon, D., McCarthy, P., Reimerdes, H., McDermott, R.M., Pucella, G., Menkovski, V., Hopf, C., Gruca, M., Merle, A., Buratti, P, Havlíčková, E., Meyer, H., Bouquey, F., Piergotti, V., Saelwski, M., Micheletti, D., Beletskii, A. A., Bufferand, H., Ricci, D., Garrido, I., Militello, F., Mitosinkova, K., Bonanomi, N., Rabinski, M., Ciraolo, G., Gobbin, M., Mlynář, J., Moiseenko, V., Wu, K., Molina Cabrera, P. A., Chellaï, Oulfa, Kazantzidis, P. V., Graves, J. P., Sheea, R. R., Pesamosca, F., Cordaro, L., Sheikh, U., Shousha, R., Goodman, T. P., Garavaglia, S., Kovacic, J., Silva, M., Offeddu, N., Sinha, J., Sozzi, C., Gath, J., Kwiatkowski, R., Hawke, J., Nespoli, F., Spolaore, M., Stipani, L., Poli, E., Gyergyek, T., Mumgaard, R. T., Bogar, O., Strand, P., Gorini, Giuseppe, Morales, J., Brida, D., Tala, T., Hubbard, A., Camenen, Y., Tema Biwole, A. S., García-Muñoz, M., Casolari, A., Teplukhina, A. A., Choi, D., Testa, D., Costea, S., Theiler, C., Thornton, A., Henderson, S., Iantchenko, A., Porte, L., Reich, M., Ricci, P., Tomaž, G., Tomes, M., Tran, M. Q., Cruz, N., Christen, N., Causa, F., Carnevale, D., Bucalossi, J., Bolzonella, T., Tsironis, C., Tsui, C. K., Bowman, C., Urban, J., Blanchard, P., Pavlinchenko, R. O., Valisa, M., Jardin, A., Pigatto, L., Vallar, M., Hakola, A., Čeřovský, J., Van Vugt, D., Hennequin, P., Ayllón Guerola, Juan Manuel, Carpanese , F., Naulin, V., Vartanian, S., Vasilovici, O., Geiger, B., Buermans, J., Nielsen, A. H., Verhaegh, K., Vermare, L., Gospodarczyk, M., Bombarda, T., Kurki-Suonio, T., Rispoli, N., Orsito, F. P., Czarnecka, A., Yoshida, M., Dal Molin, A., David, P., Nielsen, S. K., Moret, J. M., Sauter, O., Decker, J., Wensing, M., De Oliveira, H., Douai, D., Bernert, M., Piovesan, P., Walkden, N., Dreval, M. B., Hoppe, M., Zuin, M., Perek, A., Villone, F., Dudson, B., Dunne, M., Nocente, M., Ionita Schrittwieser, C., Duval, B. P., Nem, R. D., Keeling, D., Eich, T., Moro, A.M., Krawczyk, N., Elmore, S., Labit, B., Embréus, O., Esposito, B., Faitsch, M., Piron, C., Bin, W., EUROfusion MST1 Team, Calabró, G., Carr, M., Farník, M., Fasoli, M. A., Horáček, J., Lazzaro, E., Kudlacek, O., Kirneva, N., Isliker, H., Fedorczak, N., Felici, F., Feng, S., Innocente, P., Feng, X., Hogge, J. Ph., Ferró, G., Blanken, T. C., Zanka, P., Février, O., Ravensbergen, T., Bagnato, F., Ficker, O., Plyusnin, V., Harrison, J., Komm, M., Fil, A., Fontana, M., Rasmussen, Juul, Jacquier, R., Wauters, T., Frassinetti, L., Huang, Z., Nowak, S., Furno, I., Schneider, B. S., and Wiesenberger, M.

Abstract

The research program of the TCV tokamak ranges from conventional to advanced-tokamak scenarios and alternative divertor configurations, to exploratory plasmas driven by theoretical insight, exploiting the device's unique shaping capabilities. Disruption avoidance by real-time locked mode prevention or unlocking with electron-cyclotron resonance heating (ECRH) was thoroughly documented, using magnetic and radiation triggers. Runaway generation with high-Z noble-gas injection and runaway dissipation by subsequent Ne or Ar injection were studied for model validation. The new 1 MW neutral beam injector has expanded the parameter range, now encompassing ELMy H-modes in an ITER-like shape and nearly non-inductive H-mode discharges sustained by electron cyclotron and neutral beam current drive. In the H-mode, the pedestal pressure increases modestly with nitrogen seeding while fueling moves the density pedestal outwards, but the plasma stored energy is largely uncorrelated to either seeding or fueling. High fueling at high triangularity is key to accessing the attractive small edge-localized mode (type-II) regime. Turbulence is reduced in the core at negative triangularity, consistent with increased confinement and in accord with global gyrokinetic simulations. The geodesic acoustic mode, possibly coupled with avalanche events, has been linked with particle flow to the wall in diverted plasmas. Detachment, scrape-off layer transport, and turbulence were studied in L- and H-modes in both standard and alternative configurations (snowflake, super-X, and beyond). The detachment process is caused by power 'starvation' reducing the ionization source, with volume recombination playing only a minor role. Partial detachment in the H-mode is obtained with impurity seeding and has shown little dependence on flux expansion in standard single-null geometry. In the attached L-mode phase, increasing the outer connection length reduces the in-out heat-flow asymmetry. A doublet plasma, fea

Published
2019

18. Consistency in drift-ordered fluid equations

Author

Gath, J., Wiesenberger, M., Gath, J., and Wiesenberger, M.

Abstract

We address several concerns related to the derivation of drift-ordered fluid equations. Starting from a fully Galilean invariant fluid system, we show how consistent sets of perturbative drift-fluid equations in the case of an isothermal collisionless fluid can be obtained. Treating all the dynamical fields on equal footing in the singular-drift expansion, we show under what conditions a set of perturbative equations can have a non-trivial quasi-neutral limit. We give a suitable perturbative setup where we provide the full set of perturbative equations for obtaining the first-order corrected fields and show that all the constants of motion are preserved at each order. With the dynamical field variables under perturbative control, we subsequently provide a quantitative analysis by means of numerical simulations. With direct access to firstorder corrections, the convergence properties are addressed for different regimes of parameter space and the validity of the first-order approximation is discussed in the three settings: cold ions, hot ions, and finite charge density.

Published
2019

19. Dependence on plasma shape and plasma fueling for small edge-localized mode regimes in TCV and ASDEX Upgrade

Author

Labit, B., Eich, T., Harrer, G.F., Wolfrum, E., Bernert, M., Dunne, M.G., Frassinetti, L., Hennequin, P., Maurizio, R., Merle, A., Meyer, H., Saarelma, S., Sheikh, U., Adamek, J., Agostini, M., Aguiam, D., Akers, R., Albanese, R., Albert, C., Alessi, E., Ambrosino, R., Andrèbe, Y., Angioni, C., Apruzzese, G., Aradi, M., Arnichand, H., Auriemma, F., Avdeeva, G., Ayllon-Guerola, J.M., Bagnato, F., Bandaru, V.K., Barnes, M., Barrera-Orte, L., Bettini, P., Bilato, R., Biletskyi, O., Bilkova, P., Bin, W., Blanchard, P., Blanken, T., Bobkov, V., Bock, A., Boeyaert, D., Bogar, K., Bogar, O., Bohm, P., Bolzonella, T., Bombarda, F., Boncagni, L., Bouquey, F., Bowman, C., Brezinsek, S., Brida, D., Brunetti, D., Bucalossi, J., Buchanan, J., Buermans, J., Bufferand, H., Buller, S., Buratti, P., Burckhart, A., Calabrò, G., Calacci, L., Camenen, Y., Cannas, B., Cano Megías, P., Carnevale, D., Carpanese, F., Carr, M., Carralero, D., Carraro, L., Casolari, A., Cathey, A., Causa, F., Cavedon, M., Cecconello, M., Ceccuzzi, S., Cerovsky, J., Chapman, S., Chmielewski, P., Choi, D., Cianfarani, C., Ciraolo, G., Coda, S., Coelho, R., Colas, L., Colette, D., Cordaro, L., Cordella, F., Costea, S., Coster, D., Cruz Zabala, D.J., Cseh, G., Czarnecka, A., Cziegler, I., D’Arcangelo, O., Dal Molin, A., David, P., De Carolis, G., De Oliveira, H., Decker, J., Dejarnac, R., Delogu, R., den Harder, N., Dimitrova, M., Dolizy, F., Domínguez-Palacios Durán, J.J., Douai, D., Drenik, A., Dreval, M., Dudson, B., Dunai, D., Duval, B.P., Dux, R., Elmore, S., Embréus, O., Erdõs, B., Fable, E., Faitsch, M., Fanni, A., Farnik, M., Faust, I., Faustin, J., Fedorczak, N., Felici, F., Feng, S., Feng, X., Ferreira, J., Ferrò, G., Février, O., Ficker, O., Figini, L., Figueiredo, A., Fil, A., Fontana, M., Francesco, M., Fuchs, C., Futatani, S., Gabellieri, L., Gadariya, D., Gahle, D., Galassi, D., Gałązka, K., Galdon-Quiroga, J., Galeani, S., Gallart, D., Gallo, A., Galperti, C., Garavaglia, S., Garcia, J., Garcia-Lopez, J., Garcia-Muñoz, M., Garzotti, L., Gath, J., Geiger, B., Giacomelli, L., Giannone, L., Gibson, S., Gil, L., Giovannozzi, E., Giruzzi, G., Gobbin, M., Gonzalez-Martin, J., Goodman, T.P., Gorini, G., Gospodarczyk, M., Granucci, G., Grekov, D., Grenfell, G., Griener, M., Groth, M., Grover, O., Gruca, M., Gude, A., Guimarais, L., Gyergyek, T., Hacek, P., Hakola, A., Ham, C., Happel, T., Harrison, J., Havranek, A., Hawke, J., Henderson, S., Hesslow, L., Hitzler, F., Hnat, B., Hobirk, J., Hoelzl, M., Hogeweij, D., Hopf, C., Hoppe, M., Horacek, J., Hron, M., Huang, Z., Iantchenko, A., Iglesias, D., Igochine, V., Innocente, P., Ionita-Schrittwieser, C., Isliker, H., Ivanova-Stanik, I., Jacobsen, A., Jakubowski, M., Janky, F., Jardin, A., Jaulmes, F., Jensen, T., Jonsson, T., Kallenbach, A., Kappatou, A., Karpushov, A., Kasilov, S., Kazakov, Y., Kazantzidis, P.V., Keeling, D., Kelemen, M., Kendl, A., Kernbichler, W., Kirk, A., Kocsis, G., Komm, M., Kong, M., Korovin, V., Koubiti, M., Kovacic, J., Krawczyk, N., Krieger, K., Kripner, L., Křivská, A., Kudlacek, O., Kulyk, Y., Kurki-Suonio, T., Kwiatkowski, R., Laggner, F., Laguardia, L., Lahtinen, A., Lang, P., Likonen, J., Lipschultz, B., Liu, F., Lombroni, R., Lorenzini, R., Loschiavo, V.P., Lunt, T., Macusova, E., Madsen, J., Maggiora, R., Maljaars, B., Manas, P., Mantica, P., Mantsinen, M.J., Manz, P., Maraschek, M., Marchenko, V., Marchetto, C., Mariani, A., Marini, C., Markovic, T., Marrelli, L., Martin, P., Martín Solís, J.R., Martitsch, A., Mastrostefano, S., Matos, F., Matthews, G., Mayoral, M.-L., Mazon, D., Mazzotta, C., Mc Carthy, P., McClements, K., McDermott, R., Mcmillan, B., Meineri, C., Menkovski, V., Meshcheriakov, D., Messmer, M., Micheletti, D., Milanesio, D., Militello, F., Miron, I.G., Mlynar, J., Moiseenko, V., Molina Cabrera, P.A., Morales, J., Moret, J.-M., Moro, A., Moulton, D., Nabais, F., Naulin, V., Naydenkova, D., Nem, R.D., Nespoli, F., Newton, S., Nielsen, A.H., Nielsen, S.K., Nikolaeva, V., Nocente, M., Nowak, S., Oberkofler, M., Ochoukov, R., Ollus, P., Olsen, J., Omotani, J., Ongena, J., Orain, F., Orsitto, F.P., Paccagnella, R., Palha, A., Panaccione, L., Panek, R., Panjan, M., Papp, G., Paradela Perez, I., Parra, F., Passeri, M., Pau, A., Pautasso, G., Pavlichenko, R., Perek, A., Pericoli Radolfini, V., Pesamosca, F., Peterka, M., Petrzilka, V., Piergotti, V., Pigatto, L., Piovesan, P., Piron, C., Piron, L., Plyusnin, V., Pokol, G., Poli, E., Pölöskei, P., Popov, T., Popovic, Z., Pór, G., Porte, L., Pucella, G., Puiatti, M.E., Pütterich, T., Rabinski, M., Juul Rasmussen, J., Rasmussen, J., Rattá, G.A., Ratynskaia, S., Ravensbergen, T., Réfy, D., Reich, M., Reimerdes, H., Reimold, F., Reiser, D., Reux, C., Reznik, S., Ricci, D., Rispoli, N., Rivero-Rodriguez, J.F., Rocchi, G., Rodriguez-Ramos, M., Romano, A., Rosato, J., Rubinacci, G., Rubino, G., Ryan, D.A., Salewski, M., Salmi, A., Samaddar, D., Sanchis-Sanchez, L., Santos, J., Särkimäki, K., Sassano, M., Sauter, O., Scannell, R., Scheffer, M., Schneider, B.S., Schneider, P., Schrittwieser, R., Schubert, M., Seidl, J., Seliunin, E., Sharapov, S., Sheeba, R.R., Sias, G., Sieglin, B., Silva, C., Sipilä, S., Smith, S., Snicker, A., Solano, E.R., Hansen, S.K., Soria-Hoyo, C., Sorokovoy, E., Sozzi, C., Sperduti, A., Spizzo, G., Spolaore, M., Stejner, M., Stipani, L., Stober, J., Strand, P., Sun, H., Suttrop, W., Sytnykov, D., Szepesi, T., Tál, B., Tala, T., Tardini, G., Tardocchi, M., Teplukhina, A., Terranova, D., Testa, D., Theiler, C., Thorén, E., Thornton, A., Tilia, B., Tolias, P., Tomes, M., Toscano-Jimenez, M., Tsironis, C., Tsui, C., Tudisco, O., Urban, J., Valisa, M., Vallar, M., Vallejos Olivares, P., Valovic, M., Van Vugt, D., Vanovac, B., Varje, J., Varju, J., Varoutis, S., Vartanian, S., Vasilovici, O., Vega, J., Verdoolaege, G., Verhaegh, K., Vermare, L., Vianello, N., Vicente, J., Viezzer, E., Villone, F., Voitsekhovitch, I., Voltolina, D., Vondracek, P., Vu, N.M.T., Walkden, N., Wauters, T., Weiland, M., Weinzettl, V., Wensing, M., Wiesen, S., Wiesenberger, M., Wilkie, G., Willensdorfer, M., Wischmeier, M., Wu, K., Xiang, L., Zagorski, R., Zaloga, D., Zanca, P., Zaplotnik, R., Zebrowski, J., Zhang, W., Zisis, A., Zoletnik, S., Zuin, M., Labit, B., Eich, T., Harrer, G.F., Wolfrum, E., Bernert, M., Dunne, M.G., Frassinetti, L., Hennequin, P., Maurizio, R., Merle, A., Meyer, H., Saarelma, S., Sheikh, U., Adamek, J., Agostini, M., Aguiam, D., Akers, R., Albanese, R., Albert, C., Alessi, E., Ambrosino, R., Andrèbe, Y., Angioni, C., Apruzzese, G., Aradi, M., Arnichand, H., Auriemma, F., Avdeeva, G., Ayllon-Guerola, J.M., Bagnato, F., Bandaru, V.K., Barnes, M., Barrera-Orte, L., Bettini, P., Bilato, R., Biletskyi, O., Bilkova, P., Bin, W., Blanchard, P., Blanken, T., Bobkov, V., Bock, A., Boeyaert, D., Bogar, K., Bogar, O., Bohm, P., Bolzonella, T., Bombarda, F., Boncagni, L., Bouquey, F., Bowman, C., Brezinsek, S., Brida, D., Brunetti, D., Bucalossi, J., Buchanan, J., Buermans, J., Bufferand, H., Buller, S., Buratti, P., Burckhart, A., Calabrò, G., Calacci, L., Camenen, Y., Cannas, B., Cano Megías, P., Carnevale, D., Carpanese, F., Carr, M., Carralero, D., Carraro, L., Casolari, A., Cathey, A., Causa, F., Cavedon, M., Cecconello, M., Ceccuzzi, S., Cerovsky, J., Chapman, S., Chmielewski, P., Choi, D., Cianfarani, C., Ciraolo, G., Coda, S., Coelho, R., Colas, L., Colette, D., Cordaro, L., Cordella, F., Costea, S., Coster, D., Cruz Zabala, D.J., Cseh, G., Czarnecka, A., Cziegler, I., D’Arcangelo, O., Dal Molin, A., David, P., De Carolis, G., De Oliveira, H., Decker, J., Dejarnac, R., Delogu, R., den Harder, N., Dimitrova, M., Dolizy, F., Domínguez-Palacios Durán, J.J., Douai, D., Drenik, A., Dreval, M., Dudson, B., Dunai, D., Duval, B.P., Dux, R., Elmore, S., Embréus, O., Erdõs, B., Fable, E., Faitsch, M., Fanni, A., Farnik, M., Faust, I., Faustin, J., Fedorczak, N., Felici, F., Feng, S., Feng, X., Ferreira, J., Ferrò, G., Février, O., Ficker, O., Figini, L., Figueiredo, A., Fil, A., Fontana, M., Francesco, M., Fuchs, C., Futatani, S., Gabellieri, L., Gadariya, D., Gahle, D., Galassi, D., Gałązka, K., Galdon-Quiroga, J., Galeani, S., Gallart, D., Gallo, A., Galperti, C., Garavaglia, S., Garcia, J., Garcia-Lopez, J., Garcia-Muñoz, M., Garzotti, L., Gath, J., Geiger, B., Giacomelli, L., Giannone, L., Gibson, S., Gil, L., Giovannozzi, E., Giruzzi, G., Gobbin, M., Gonzalez-Martin, J., Goodman, T.P., Gorini, G., Gospodarczyk, M., Granucci, G., Grekov, D., Grenfell, G., Griener, M., Groth, M., Grover, O., Gruca, M., Gude, A., Guimarais, L., Gyergyek, T., Hacek, P., Hakola, A., Ham, C., Happel, T., Harrison, J., Havranek, A., Hawke, J., Henderson, S., Hesslow, L., Hitzler, F., Hnat, B., Hobirk, J., Hoelzl, M., Hogeweij, D., Hopf, C., Hoppe, M., Horacek, J., Hron, M., Huang, Z., Iantchenko, A., Iglesias, D., Igochine, V., Innocente, P., Ionita-Schrittwieser, C., Isliker, H., Ivanova-Stanik, I., Jacobsen, A., Jakubowski, M., Janky, F., Jardin, A., Jaulmes, F., Jensen, T., Jonsson, T., Kallenbach, A., Kappatou, A., Karpushov, A., Kasilov, S., Kazakov, Y., Kazantzidis, P.V., Keeling, D., Kelemen, M., Kendl, A., Kernbichler, W., Kirk, A., Kocsis, G., Komm, M., Kong, M., Korovin, V., Koubiti, M., Kovacic, J., Krawczyk, N., Krieger, K., Kripner, L., Křivská, A., Kudlacek, O., Kulyk, Y., Kurki-Suonio, T., Kwiatkowski, R., Laggner, F., Laguardia, L., Lahtinen, A., Lang, P., Likonen, J., Lipschultz, B., Liu, F., Lombroni, R., Lorenzini, R., Loschiavo, V.P., Lunt, T., Macusova, E., Madsen, J., Maggiora, R., Maljaars, B., Manas, P., Mantica, P., Mantsinen, M.J., Manz, P., Maraschek, M., Marchenko, V., Marchetto, C., Mariani, A., Marini, C., Markovic, T., Marrelli, L., Martin, P., Martín Solís, J.R., Martitsch, A., Mastrostefano, S., Matos, F., Matthews, G., Mayoral, M.-L., Mazon, D., Mazzotta, C., Mc Carthy, P., McClements, K., McDermott, R., Mcmillan, B., Meineri, C., Menkovski, V., Meshcheriakov, D., Messmer, M., Micheletti, D., Milanesio, D., Militello, F., Miron, I.G., Mlynar, J., Moiseenko, V., Molina Cabrera, P.A., Morales, J., Moret, J.-M., Moro, A., Moulton, D., Nabais, F., Naulin, V., Naydenkova, D., Nem, R.D., Nespoli, F., Newton, S., Nielsen, A.H., Nielsen, S.K., Nikolaeva, V., Nocente, M., Nowak, S., Oberkofler, M., Ochoukov, R., Ollus, P., Olsen, J., Omotani, J., Ongena, J., Orain, F., Orsitto, F.P., Paccagnella, R., Palha, A., Panaccione, L., Panek, R., Panjan, M., Papp, G., Paradela Perez, I., Parra, F., Passeri, M., Pau, A., Pautasso, G., Pavlichenko, R., Perek, A., Pericoli Radolfini, V., Pesamosca, F., Peterka, M., Petrzilka, V., Piergotti, V., Pigatto, L., Piovesan, P., Piron, C., Piron, L., Plyusnin, V., Pokol, G., Poli, E., Pölöskei, P., Popov, T., Popovic, Z., Pór, G., Porte, L., Pucella, G., Puiatti, M.E., Pütterich, T., Rabinski, M., Juul Rasmussen, J., Rasmussen, J., Rattá, G.A., Ratynskaia, S., Ravensbergen, T., Réfy, D., Reich, M., Reimerdes, H., Reimold, F., Reiser, D., Reux, C., Reznik, S., Ricci, D., Rispoli, N., Rivero-Rodriguez, J.F., Rocchi, G., Rodriguez-Ramos, M., Romano, A., Rosato, J., Rubinacci, G., Rubino, G., Ryan, D.A., Salewski, M., Salmi, A., Samaddar, D., Sanchis-Sanchez, L., Santos, J., Särkimäki, K., Sassano, M., Sauter, O., Scannell, R., Scheffer, M., Schneider, B.S., Schneider, P., Schrittwieser, R., Schubert, M., Seidl, J., Seliunin, E., Sharapov, S., Sheeba, R.R., Sias, G., Sieglin, B., Silva, C., Sipilä, S., Smith, S., Snicker, A., Solano, E.R., Hansen, S.K., Soria-Hoyo, C., Sorokovoy, E., Sozzi, C., Sperduti, A., Spizzo, G., Spolaore, M., Stejner, M., Stipani, L., Stober, J., Strand, P., Sun, H., Suttrop, W., Sytnykov, D., Szepesi, T., Tál, B., Tala, T., Tardini, G., Tardocchi, M., Teplukhina, A., Terranova, D., Testa, D., Theiler, C., Thorén, E., Thornton, A., Tilia, B., Tolias, P., Tomes, M., Toscano-Jimenez, M., Tsironis, C., Tsui, C., Tudisco, O., Urban, J., Valisa, M., Vallar, M., Vallejos Olivares, P., Valovic, M., Van Vugt, D., Vanovac, B., Varje, J., Varju, J., Varoutis, S., Vartanian, S., Vasilovici, O., Vega, J., Verdoolaege, G., Verhaegh, K., Vermare, L., Vianello, N., Vicente, J., Viezzer, E., Villone, F., Voitsekhovitch, I., Voltolina, D., Vondracek, P., Vu, N.M.T., Walkden, N., Wauters, T., Weiland, M., Weinzettl, V., Wensing, M., Wiesen, S., Wiesenberger, M., Wilkie, G., Willensdorfer, M., Wischmeier, M., Wu, K., Xiang, L., Zagorski, R., Zaloga, D., Zanca, P., Zaplotnik, R., Zebrowski, J., Zhang, W., Zisis, A., Zoletnik, S., and Zuin, M.

Abstract

Within the EUROfusion MST1 work package, a series of experiments has been conducted on AUG and TCV devices to disentangle the role of plasma fueling and plasma shape for the onset of small ELM regimes. On both devices, small ELM regimes with high confinement are achieved if and only if two conditions are fulfilled at the same time. Firstly, the plasma density at the separatrix must be large enough (ne,sep/nG ~ 0.3), leading to a pressure profile flattening at the separatrix, which stabilizes type-I ELMs. Secondly, the magnetic configuration has to be close to a double null (DN), leading to a reduction of the magnetic shear in the extreme vicinity of the separatrix. As a consequence, its stabilizing effect on ballooning modes is weakened.

Published
2019

20. Physics research on the TCV tokamak facility: from conventional to alternative scenarios and beyond

Author

Coda, S., primary, Agostini, M., additional, Albanese, R., additional, Alberti, S., additional, Alessi, E., additional, Allan, S., additional, Allcock, J., additional, Ambrosino, R., additional, Anand, H., additional, Andrèbe, Y., additional, Arnichand, H., additional, Auriemma, F., additional, Ayllon-Guerola, J.M., additional, Bagnato, F., additional, Ball, J., additional, Baquero-Ruiz, M., additional, Beletskii, A.A., additional, Bernert, M., additional, Bin, W., additional, Blanchard, P., additional, Blanken, T.C., additional, Boedo, J.A., additional, Bogar, O., additional, Bolzonella, T., additional, Bombarda, F., additional, Bonanomi, N., additional, Bouquey, F., additional, Bowman, C., additional, Brida, D., additional, Bucalossi, J., additional, Buermans, J., additional, Bufferand, H., additional, Buratti, P., additional, Calabró, G., additional, Calacci, L., additional, Camenen, Y., additional, Carnevale, D., additional, Carpanese, F., additional, Carr, M., additional, Carraro, L., additional, Casolari, A., additional, Causa, F., additional, Čeřovský, J., additional, Chellaï, O., additional, Chmielewski, P., additional, Choi, D., additional, Christen, N., additional, Ciraolo, G., additional, Cordaro, L., additional, Costea, S., additional, Cruz, N., additional, Czarnecka, A., additional, Dal Molin, A., additional, David, P., additional, Decker, J., additional, De Oliveira, H., additional, Douai, D., additional, Dreval, M.B., additional, Dudson, B., additional, Dunne, M., additional, Duval, B.P., additional, Eich, T., additional, Elmore, S., additional, Embréus, O., additional, Esposito, B., additional, Faitsch, M., additional, Farník, M., additional, Fasoli, A., additional, Fedorczak, N., additional, Felici, F., additional, Feng, S., additional, Feng, X., additional, Ferró, G., additional, Février, O., additional, Ficker, O., additional, Fil, A., additional, Fontana, M., additional, Frassinetti, L., additional, Furno, I., additional, Gahle, D.S., additional, Galassi, D., additional, Gałązka, K., additional, Gallo, A., additional, Galperti, C., additional, Garavaglia, S., additional, Garcia, J., additional, Garcia-Muñoz, M., additional, Garrido, A.J., additional, Garrido, I., additional, Gath, J., additional, Geiger, B., additional, Giruzzi, G., additional, Gobbin, M., additional, Goodman, T.P., additional, Gorini, G., additional, Gospodarczyk, M., additional, Granucci, G., additional, Graves, J.P., additional, Gruca, M., additional, Gyergyek, T., additional, Hakola, A., additional, Happel, T., additional, Harrer, G.F., additional, Harrison, J., additional, Havlíčková, E., additional, Hawke, J., additional, Henderson, S., additional, Hennequin, P., additional, Hesslow, L., additional, Hogeweij, D., additional, Hogge, J.-Ph., additional, Hopf, C., additional, Hoppe, M., additional, Horáček, J., additional, Huang, Z., additional, Hubbard, A., additional, Iantchenko, A., additional, Igochine, V., additional, Innocente, P., additional, Ionita Schrittwieser, C., additional, Isliker, H., additional, Jacquier, R., additional, Jardin, A., additional, Kappatou, A., additional, Karpushov, A., additional, Kazantzidis, P.-V., additional, Keeling, D., additional, Kirneva, N., additional, Komm, M., additional, Kong, M., additional, Kovacic, J., additional, Krawczyk, N., additional, Kudlacek, O., additional, Kurki-Suonio, T., additional, Kwiatkowski, R., additional, Labit, B., additional, Lazzaro, E., additional, Linehan, B., additional, Lipschultz, B., additional, Llobet, X., additional, Lombroni, R., additional, Loschiavo, V.P., additional, Lunt, T., additional, Macusova, E., additional, Madsen, J., additional, Maljaars, E., additional, Mantica, P., additional, Maraschek, M., additional, Marchetto, C., additional, Marco, A., additional, Mariani, A., additional, Marini, C., additional, Martin, Y., additional, Matos, F., additional, Maurizio, R., additional, Mavkov, B., additional, Mazon, D., additional, McCarthy, P., additional, McDermott, R., additional, Menkovski, V., additional, Merle, A., additional, Meyer, H., additional, Micheletti, D., additional, Militello, F., additional, Mitosinkova, K., additional, Mlynář, J., additional, Moiseenko, V., additional, Molina Cabrera, P.A., additional, Morales, J., additional, Moret, J.-M., additional, Moro, A., additional, Mumgaard, R.T., additional, Naulin, V., additional, Nem, R.D., additional, Nespoli, F., additional, Nielsen, A.H., additional, Nielsen, S.K., additional, Nocente, M., additional, Nowak, S., additional, Offeddu, N., additional, Orsitto, F.P., additional, Paccagnella, R., additional, Palha, A., additional, Papp, G., additional, Pau, A., additional, Pavlichenko, R.O., additional, Perek, A., additional, Pericoli Ridolfini, V., additional, Pesamosca, F., additional, Piergotti, V., additional, Pigatto, L., additional, Piovesan, P., additional, Piron, C., additional, Plyusnin, V., additional, Poli, E., additional, Porte, L., additional, Pucella, G., additional, Puiatti, M.E., additional, Pütterich, T., additional, Rabinski, M., additional, Juul Rasmussen, J., additional, Ravensbergen, T., additional, Reich, M., additional, Reimerdes, H., additional, Reimold, F., additional, Reux, C., additional, Ricci, D., additional, Ricci, P., additional, Rispoli, N., additional, Rosato, J., additional, Saarelma, S., additional, Salewski, M., additional, Salmi, A., additional, Sauter, O., additional, Scheffer, M., additional, Schlatter, Ch., additional, Schneider, B.S., additional, Schrittwieser, R., additional, Sharapov, S., additional, Sheeba, R.R., additional, Sheikh, U., additional, Shousha, R., additional, Silva, M., additional, Sinha, J., additional, Sozzi, C., additional, Spolaore, M., additional, Stipani, L., additional, Strand, P., additional, Tala, T., additional, Tema Biwole, A.S., additional, Teplukhina, A.A., additional, Testa, D., additional, Theiler, C., additional, Thornton, A., additional, Tomaž, G., additional, Tomes, M., additional, Tran, M.Q., additional, Tsironis, C., additional, Tsui, C.K., additional, Urban, J., additional, Valisa, M., additional, Vallar, M., additional, Van Vugt, D., additional, Vartanian, S., additional, Vasilovici, O., additional, Verhaegh, K., additional, Vermare, L., additional, Vianello, N., additional, Viezzer, E., additional, Vijvers, W.A.J., additional, Villone, F., additional, Voitsekhovitch, I., additional, Vu, N.M.T., additional, Walkden, N., additional, Wauters, T., additional, Weiland, M., additional, Weisen, H., additional, Wensing, M., additional, Wiesenberger, M., additional, Wilkie, G., additional, Wischmeier, M., additional, Wu, K., additional, Yoshida, M., additional, Zagorski, R., additional, Zanca, P., additional, Zebrowski, J., additional, Zisis, A., additional, and Zuin, M., additional

Published
2019
Full Text
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21. Dependence on plasma shape and plasma fueling for small edge-localized mode regimes in TCV and ASDEX Upgrade

Author

Labit, B., primary, Eich, T., additional, Harrer, G.F., additional, Wolfrum, E., additional, Bernert, M., additional, Dunne, M.G., additional, Frassinetti, L., additional, Hennequin, P., additional, Maurizio, R., additional, Merle, A., additional, Meyer, H., additional, Saarelma, S., additional, Sheikh, U., additional, Adamek, J., additional, Agostini, M., additional, Aguiam, D., additional, Akers, R., additional, Albanese, R., additional, Albert, C., additional, Alessi, E., additional, Ambrosino, R., additional, Andrèbe, Y., additional, Angioni, C., additional, Apruzzese, G., additional, Aradi, M., additional, Arnichand, H., additional, Auriemma, F., additional, Avdeeva, G., additional, Ayllon-Guerola, J.M., additional, Bagnato, F., additional, Bandaru, V.K., additional, Barnes, M., additional, Barrera-Orte, L., additional, Bettini, P., additional, Bilato, R., additional, Biletskyi, O., additional, Bilkova, P., additional, Bin, W., additional, Blanchard, P., additional, Blanken, T., additional, Bobkov, V., additional, Bock, A., additional, Boeyaert, D., additional, Bogar, K., additional, Bogar, O., additional, Bohm, P., additional, Bolzonella, T., additional, Bombarda, F., additional, Boncagni, L., additional, Bouquey, F., additional, Bowman, C., additional, Brezinsek, S., additional, Brida, D., additional, Brunetti, D., additional, Bucalossi, J., additional, Buchanan, J., additional, Buermans, J., additional, Bufferand, H., additional, Buller, S., additional, Buratti, P., additional, Burckhart, A., additional, Calabrò, G., additional, Calacci, L., additional, Camenen, Y., additional, Cannas, B., additional, Cano Megías, P., additional, Carnevale, D., additional, Carpanese, F., additional, Carr, M., additional, Carralero, D., additional, Carraro, L., additional, Casolari, A., additional, Cathey, A., additional, Causa, F., additional, Cavedon, M., additional, Cecconello, M., additional, Ceccuzzi, S., additional, Cerovsky, J., additional, Chapman, S., additional, Chmielewski, P., additional, Choi, D., additional, Cianfarani, C., additional, Ciraolo, G., additional, Coda, S., additional, Coelho, R., additional, Colas, L., additional, Colette, D., additional, Cordaro, L., additional, Cordella, F., additional, Costea, S., additional, Coster, D., additional, Cruz Zabala, D.J., additional, Cseh, G., additional, Czarnecka, A., additional, Cziegler, I., additional, D’Arcangelo, O., additional, Dal Molin, A., additional, David, P., additional, De Carolis, G., additional, De Oliveira, H., additional, Decker, J., additional, Dejarnac, R., additional, Delogu, R., additional, den Harder, N., additional, Dimitrova, M., additional, Dolizy, F., additional, Domínguez-Palacios Durán, J.J., additional, Douai, D., additional, Drenik, A., additional, Dreval, M., additional, Dudson, B., additional, Dunai, D., additional, Duval, B.P., additional, Dux, R., additional, Elmore, S., additional, Embréus, O., additional, Erdõs, B., additional, Fable, E., additional, Faitsch, M., additional, Fanni, A., additional, Farnik, M., additional, Faust, I., additional, Faustin, J., additional, Fedorczak, N., additional, Felici, F., additional, Feng, S., additional, Feng, X., additional, Ferreira, J., additional, Ferrò, G., additional, Février, O., additional, Ficker, O., additional, Figini, L., additional, Figueiredo, A., additional, Fil, A., additional, Fontana, M., additional, Francesco, M., additional, Fuchs, C., additional, Futatani, S., additional, Gabellieri, L., additional, Gadariya, D., additional, Gahle, D., additional, Galassi, D., additional, Gałązka, K., additional, Galdon-Quiroga, J., additional, Galeani, S., additional, Gallart, D., additional, Gallo, A., additional, Galperti, C., additional, Garavaglia, S., additional, Garcia, J., additional, Garcia-Lopez, J., additional, Garcia-Muñoz, M., additional, Garzotti, L., additional, Gath, J., additional, Geiger, B., additional, Giacomelli, L., additional, Giannone, L., additional, Gibson, S., additional, Gil, L., additional, Giovannozzi, E., additional, Giruzzi, G., additional, Gobbin, M., additional, Gonzalez-Martin, J., additional, Goodman, T.P., additional, Gorini, G., additional, Gospodarczyk, M., additional, Granucci, G., additional, Grekov, D., additional, Grenfell, G., additional, Griener, M., additional, Groth, M., additional, Grover, O., additional, Gruca, M., additional, Gude, A., additional, Guimarais, L., additional, Gyergyek, T., additional, Hacek, P., additional, Hakola, A., additional, Ham, C., additional, Happel, T., additional, Harrison, J., additional, Havranek, A., additional, Hawke, J., additional, Henderson, S., additional, Hesslow, L., additional, Hitzler, F., additional, Hnat, B., additional, Hobirk, J., additional, Hoelzl, M., additional, Hogeweij, D., additional, Hopf, C., additional, Hoppe, M., additional, Horacek, J., additional, Hron, M., additional, Huang, Z., additional, Iantchenko, A., additional, Iglesias, D., additional, Igochine, V., additional, Innocente, P., additional, Ionita-Schrittwieser, C., additional, Isliker, H., additional, Ivanova-Stanik, I., additional, Jacobsen, A., additional, Jakubowski, M., additional, Janky, F., additional, Jardin, A., additional, Jaulmes, F., additional, Jensen, T., additional, Jonsson, T., additional, Kallenbach, A., additional, Kappatou, A., additional, Karpushov, A., additional, Kasilov, S., additional, Kazakov, Y., additional, Kazantzidis, P.V., additional, Keeling, D., additional, Kelemen, M., additional, Kendl, A., additional, Kernbichler, W., additional, Kirk, A., additional, Kocsis, G., additional, Komm, M., additional, Kong, M., additional, Korovin, V., additional, Koubiti, M., additional, Kovacic, J., additional, Krawczyk, N., additional, Krieger, K., additional, Kripner, L., additional, Křivská, A., additional, Kudlacek, O., additional, Kulyk, Y., additional, Kurki-Suonio, T., additional, Kwiatkowski, R., additional, Laggner, F., additional, Laguardia, L., additional, Lahtinen, A., additional, Lang, P., additional, Likonen, J., additional, Lipschultz, B., additional, Liu, F., additional, Lombroni, R., additional, Lorenzini, R., additional, Loschiavo, V.P., additional, Lunt, T., additional, Macusova, E., additional, Madsen, J., additional, Maggiora, R., additional, Maljaars, B., additional, Manas, P., additional, Mantica, P., additional, Mantsinen, M.J., additional, Manz, P., additional, Maraschek, M., additional, Marchenko, V., additional, Marchetto, C., additional, Mariani, A., additional, Marini, C., additional, Markovic, T., additional, Marrelli, L., additional, Martin, P., additional, Martín Solís, J.R., additional, Martitsch, A., additional, Mastrostefano, S., additional, Matos, F., additional, Matthews, G., additional, Mayoral, M.-L., additional, Mazon, D., additional, Mazzotta, C., additional, Mc Carthy, P., additional, McClements, K., additional, McDermott, R., additional, Mcmillan, B., additional, Meineri, C., additional, Menkovski, V., additional, Meshcheriakov, D., additional, Messmer, M., additional, Micheletti, D., additional, Milanesio, D., additional, Militello, F., additional, Miron, I.G., additional, Mlynar, J., additional, Moiseenko, V., additional, Molina Cabrera, P.A., additional, Morales, J., additional, Moret, J.-M., additional, Moro, A., additional, Moulton, D., additional, Nabais, F., additional, Naulin, V., additional, Naydenkova, D., additional, Nem, R.D., additional, Nespoli, F., additional, Newton, S., additional, Nielsen, A.H., additional, Nielsen, S.K., additional, Nikolaeva, V., additional, Nocente, M., additional, Nowak, S., additional, Oberkofler, M., additional, Ochoukov, R., additional, Ollus, P., additional, Olsen, J., additional, Omotani, J., additional, Ongena, J., additional, Orain, F., additional, Orsitto, F.P., additional, Paccagnella, R., additional, Palha, A., additional, Panaccione, L., additional, Panek, R., additional, Panjan, M., additional, Papp, G., additional, Paradela Perez, I., additional, Parra, F., additional, Passeri, M., additional, Pau, A., additional, Pautasso, G., additional, Pavlichenko, R., additional, Perek, A., additional, Pericoli Radolfini, V., additional, Pesamosca, F., additional, Peterka, M., additional, Petrzilka, V., additional, Piergotti, V., additional, Pigatto, L., additional, Piovesan, P., additional, Piron, C., additional, Piron, L., additional, Plyusnin, V., additional, Pokol, G., additional, Poli, E., additional, Pölöskei, P., additional, Popov, T., additional, Popovic, Z., additional, Pór, G., additional, Porte, L., additional, Pucella, G., additional, Puiatti, M.E., additional, Pütterich, T., additional, Rabinski, M., additional, Juul Rasmussen, J., additional, Rasmussen, J., additional, Rattá, G.A., additional, Ratynskaia, S., additional, Ravensbergen, T., additional, Réfy, D., additional, Reich, M., additional, Reimerdes, H., additional, Reimold, F., additional, Reiser, D., additional, Reux, C., additional, Reznik, S., additional, Ricci, D., additional, Rispoli, N., additional, Rivero-Rodriguez, J.F., additional, Rocchi, G., additional, Rodriguez-Ramos, M., additional, Romano, A., additional, Rosato, J., additional, Rubinacci, G., additional, Rubino, G., additional, Ryan, D.A., additional, Salewski, M., additional, Salmi, A., additional, Samaddar, D., additional, Sanchis-Sanchez, L., additional, Santos, J., additional, Särkimäki, K., additional, Sassano, M., additional, Sauter, O., additional, Scannell, R., additional, Scheffer, M., additional, Schneider, B.S., additional, Schneider, P., additional, Schrittwieser, R., additional, Schubert, M., additional, Seidl, J., additional, Seliunin, E., additional, Sharapov, S., additional, Sheeba, R.R., additional, Sias, G., additional, Sieglin, B., additional, Silva, C., additional, Sipilä, S., additional, Smith, S., additional, Snicker, A., additional, Solano, E.R., additional, Hansen, S.K., additional, Soria-Hoyo, C., additional, Sorokovoy, E., additional, Sozzi, C., additional, Sperduti, A., additional, Spizzo, G., additional, Spolaore, M., additional, Stejner, M., additional, Stipani, L., additional, Stober, J., additional, Strand, P., additional, Sun, H., additional, Suttrop, W., additional, Sytnykov, D., additional, Szepesi, T., additional, Tál, B., additional, Tala, T., additional, Tardini, G., additional, Tardocchi, M., additional, Teplukhina, A., additional, Terranova, D., additional, Testa, D., additional, Theiler, C., additional, Thorén, E., additional, Thornton, A., additional, Tilia, B., additional, Tolias, P., additional, Tomes, M., additional, Toscano-Jimenez, M., additional, Tsironis, C., additional, Tsui, C., additional, Tudisco, O., additional, Urban, J., additional, Valisa, M., additional, Vallar, M., additional, Vallejos Olivares, P., additional, Valovic, M., additional, Van Vugt, D., additional, Vanovac, B., additional, Varje, J., additional, Varju, J., additional, Varoutis, S., additional, Vartanian, S., additional, Vasilovici, O., additional, Vega, J., additional, Verdoolaege, G., additional, Verhaegh, K., additional, Vermare, L., additional, Vianello, N., additional, Vicente, J., additional, Viezzer, E., additional, Villone, F., additional, Voitsekhovitch, I., additional, Voltolina, D., additional, Vondracek, P., additional, Vu, N.M.T., additional, Walkden, N., additional, Wauters, T., additional, Weiland, M., additional, Weinzettl, V., additional, Wensing, M., additional, Wiesen, S., additional, Wiesenberger, M., additional, Wilkie, G., additional, Willensdorfer, M., additional, Wischmeier, M., additional, Wu, K., additional, Xiang, L., additional, Zagorski, R., additional, Zaloga, D., additional, Zanca, P., additional, Zaplotnik, R., additional, Zebrowski, J., additional, Zhang, W., additional, Zisis, A., additional, Zoletnik, S., additional, and Zuin, M., additional

Published
2019
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23. Comparison of quality of life of older women treated with surgery or primary endocrine therapy for early breast cancer: propensity score matched analysis of a large prospective multicentre cohort study

Author

Shrestha, A., primary, Martin, C., additional, Burton, M., additional, Collins, K., additional, Holmes, G., additional, Ward, S., additional, Audisio, R., additional, Chater, T., additional, Pemberton, K., additional, Robinson, T., additional, Cheung, K.L., additional, Ring, A., additional, Walters, S., additional, Reed, M., additional, Gath, J., additional, Green, T., additional, Revell, D., additional, and Wyld, L., additional

Published
2018
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24. Observational study of the development and evaluation of a fertility preservation patient decision aid for teenage and adult women diagnosed with cancer: The Cancer, Fertility and Me research protocol

Author

Jones, GL, Hughes, J, Mahmoodi, N, Greenfield, D, Brauten-Smith, G, Skull, J, Gath, J, Yeomanson, D, Baskind, E, Snowden, J, Jacques, RM, Velikova, G, Collins, K, Stark, D, Phillips, R, Lane, S, Bekker, HL, Jones, GL, Hughes, J, Mahmoodi, N, Greenfield, D, Brauten-Smith, G, Skull, J, Gath, J, Yeomanson, D, Baskind, E, Snowden, J, Jacques, RM, Velikova, G, Collins, K, Stark, D, Phillips, R, Lane, S, and Bekker, HL

Abstract

Introduction: Women diagnosed with cancer and facing potentially sterilising cancer treatment have to make time-pressured decisions regarding fertility preservation with specialist fertility services whilst undergoing treatment of their cancer with oncology services. Oncologists identify a need for resources enabling them to support women’s fertility preservation decisions more effectively; women report wanting more specialist information to make these decisions. The overall aim of the ‘Cancer, Fertility and Me’ study is to develop and evaluate a new evidence-based patient decision aid (ptDA) for women with any cancer considering fertility preservation to address this unmet need. Methods and analysis: This is a prospective mixed-method observational study including women of reproductive age (16 years +) with a new diagnosis of any cancer across two regional cancer and fertility centres in Yorkshire, UK. The research involves three stages. In Stage 1 the aim is to develop the ptDA using a systematic method of evidence synthesis and multidisciplinary expert review of current clinical practice and patient information. In Stage 2, the aim is to assess the face validity of the ptDA. Feedback on its content and format will be ascertained using both questionnaires and interviews with patients, user groups and key stakeholders. Finally, in Stage 3 the acceptability of using this resource when integrated into usual cancer care pathways at the point of cancer diagnosis and treatment planning will be evaluated. This will involve a quantitative and qualitative evaluation of the ptDA in clinical practice. Measures chosen include using count data of the ptDAs administered in clinics and accessed online, decisional and patient-reported outcome measures and qualitative feedback. Quantitative data will be analysed using descriptive statistics, paired sample t tests and confidence intervals; interviews will be analysed using thematic analysis. Ethics and dissemination: Research Ethic

Published
2017

25. THE DEVELOPMENT OF A FERTILITY PRESERVATION DECISION AID TO SUPPORT TEENAGE AND ADULT WOMEN WITH CANCER

Author

Jones, G, Hughes, J, Mahmoodi, N, Greenfield, D, Brauten-Smith, G, Skull, J, Gath, J, Yeomanson D4, D, Lane, S, Phillips, B, Stark, D, Jacques, R, Baskind, E, Velikova, G, Collins, K, and Bekker, HL

Abstract

Introduction We describe the protocol for a recently funded three-year study (Yorkshire Cancer Research). Our aims are to develop a new evidence based fertility preservation (FP) decision aid (DA) and evaluate the impact of administering this resource at the point of cancer diagnosis/cancer treatment planning stage in oncology. While a few DAs exist to support the FP process, they are exclusively for breast cancer patients, and none have been developed for the UK female cancer population. Method A multi-centre prospective mixed-method observational study including teenage and adult women of reproductive age (16 years +) with a new diagnosis of any cancer attending cancer hospitals across two large Yorkshire cities. The study involves three stages: Stage 1 (Development of the DA), Stage 2 (Assessing the Learner Verification of the DA), Stage 3 (A quantitative and qualitative evaluation of the DA in routine clinical care). Results We are currently in Stage 1. NHS Research Ethics Committee approval has been granted. The content of the DA is being informed by a systematic literature review, an environmental scan of publically available literature, a previous three-year study carried out in Sheffield alongside clinical evidence from oncology and fertility guidelines and international patient decision aids standards. Discussion It is anticipated that our new DA will enable teenage and adult women to feel better supported and make more informed FP treatment decisions. It should also raise fertility awareness and improve the care of the women whilst they make FP choices and transition between oncology and fertility services.

Published
2016

26. Observational study of the development and evaluation of a fertility preservation patient decision aid for teenage and adult women diagnosed with cancer: the Cancer, Fertility and Me research protocol

Author

Jones, G L, primary, Hughes, J, additional, Mahmoodi, N, additional, Greenfield, D, additional, Brauten-Smith, G, additional, Skull, J, additional, Gath, J, additional, Yeomanson, D, additional, Baskind, E, additional, Snowden, J A, additional, Jacques, R M, additional, Velikova, G, additional, Collins, K, additional, Stark, D, additional, Phillips, R, additional, Lane, S, additional, and Bekker, H L, additional

Published
2017
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27. The ACCURE-UK trial: The effect of appendectomy on the clinical course of ulcerative colitis – A feasibility study

Author

Nepogodiev, D., primary, Howard, R., additional, Pathmakanthan, S., additional, Iqbal, T., additional, Singh, B., additional, Oo, Y., additional, Mathers, J., additional, McMullan, C., additional, Sahamai, S., additional, Gath, J., additional, Magill, L., additional, Handley, K., additional, Deeks, J., additional, Bemelman, W., additional, Morton, D., additional, and Pinkney, T., additional

Published
2016
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28. The information and decision support needs of older women (>75 yrs) facing treatment choices for breast cancer : a qualitative study

Author

Burton, Maria, Collins, Karen, Lifford, K, Brain, K, Wyld, L, Caldon, L, Gath, J, Revell, D, and Reed, M

Abstract

Objective\ud \ud Primary Endocrine Therapy (PET) is a good alternative to surgery for breast cancer in older frailer women. Overall survival rates are equivalent although rates of local control are inferior. There is little research regarding the decision support needs of older patients faced with this choice. This qualitative study aimed to explore these among older breast cancer patients offered a choice of treatment, as the basis to develop an appropriate decision support tool.\ud \ud \ud Methods\ud \ud \ud Semi-structured interviews were undertaken with older women (>75 years) with breast cancer who had been offered a choice of PET or surgery at diagnosis. Women's involvement in their treatment decision and support for the process were explored and analysed using framework analysis.\ud \ud \ud Results\ud \ud \ud Thirty-three interviews were undertaken (median age 82, range 75–95 years, 22 PET, 11 surgery). Most women, regardless of treatment choice, wanted tailored information about the different treatment options, their impact on independence, the practicalities of treatment and the risk of recurrence and spread. Surgery was the treatment of choice in women wanting optimal disease control; those choosing PET felt that they were ‘too old’ for surgery and wanted minimal disruption.\ud \ud \ud Conclusions\ud \ud \ud Older women described making active treatment decisions. However, some knowledge was inaccurate. Women wanted information and decision support from their clinicians along with a specific tailored information booklet to support this process

Published
2014

42. Physics research on the TCV tokamak facility: From conventional to alternative scenarios and beyond

Author

G. Tomaž, M. Weiland, J. Gath, Antti Hakola, Kevin Verhaegh, A.J. Thornton, Matthew Carr, J. Juul Rasmussen, S. Costea, Jorge Morales, A. Perek, X. Feng, F. Pesamosca, Marcelo Baquero-Ruiz, N. Vianello, A. Dal Molin, N. M. T. Vu, D. Hogeweij, G. Calabrò, Tom Wauters, Christian Hopf, E. Alessi, Aitor J. Garrido, Justin Ball, Daniele Carnevale, A. Czarnecka, S. Garavaglia, G. Ferro, George Wilkie, N. Krawczyk, M. Nocente, H. De Oliveira, Ivo Furno, W. Bin, O. Chellai, Stefano Coda, Fulvio Auriemma, Yann Camenen, W. A. J. Vijvers, Christian Theiler, A. N. Karpushov, M. Faitsch, Jérôme Bucalossi, Paolo Ricci, Antoine Merle, T. C. Blanken, Cristian Galperti, Duccio Testa, Ambrogio Fasoli, Y. Andrebe, F. Bagnato, S. Nowak, J. R. Harrison, O. Vasilovici, M. E. Puiatti, Stefan Kragh Nielsen, J. S. Allcock, L. Calacci, Matteo Zuin, V. Piergotti, P. Chmielewski, P. Molina Cabrera, Taina Kurki-Suonio, D. Micheletti, Emanuele Poli, Nuno Cruz, M. Farnik, Jonathan Graves, Alessandro Pau, Olivier Février, N. A. Kirneva, Bruce Lipschultz, E. Lazzaro, E. Havlickova, G. Giruzzi, Jens Madsen, L. Stipani, D. Brida, Ch. Schlatter, M. Wensing, R. O. Pavlichenko, F. Nespoli, J. Decker, Eva Macusova, Fulvio Militello, Nicola Offeddu, Heinz Isliker, A. Zisis, A. Marco, Laurie Porte, Marco Gobbin, Anna Salmi, S. Vartanian, J. Sinha, Matthias Komm, M. Spolaore, Anders Nielsen, T. Happel, R. D. Nem, A. Iantchenko, V.V. Plyusnin, C. Tsironis, V. Igochine, R. M. McDermott, Pär Strand, Benjamin Daniel Dudson, T. Ravensbergen, V. P. Loschiavo, H. Arnichand, E. Viezzer, Fabio Villone, Carlo Sozzi, Z. Huang, V. Pericoli Ridolfini, B. Linehan, L. Hesslow, P. Buratti, A. Casolari, M. Bernert, P. Mantica, H. Weisen, J-M Moret, Maiko Yoshida, N. Bonanomi, S. Feng, A. A. Teplukhina, Jakub Urban, F. Carpanese, C. Piron, S. Allan, Minh Quang Tran, C. Marini, Artur Palha, F.P. Orsitto, Roberto Ambrosino, A. S. Tema Biwole, Harry M. Meyer, Davide Galassi, J. Mlynář, N. Christen, M. Wischmeier, Mathias Hoppe, P. David, J. Horacek, M. Maraschek, G. Ciraolo, R. R. Sheeba, J. Zebrowski, M. Dreval, M. Silva, K. Gałązka, Olivier Sauter, Laure Vermare, A. Gallo, C. Reux, M. Gospodarczyk, O. Bogar, Roman Schrittwieser, C. Marchetto, Patrick J. McCarthy, Joël Rosato, G. Pucella, K. Wu, Volker Naulin, Bojan Mavkov, S. Elmore, Lorella Carraro, Gustavo Granucci, Christopher N. Bowman, O. Kudlacek, M. Gruca, A. Jardin, Federico Felici, Didier Mazon, D. C. van Vugt, D. Douai, Jose Boedo, Raffaele Albanese, U. A. Sheikh, Hugo Bufferand, R. Lombroni, T. Pütterich, Benedikt Geiger, X. Llobet, Izaskun Garrido, J.-Ph. Hogge, J. Ayllon-Guerola, Nicolas Fedorczak, Timothy Goodman, A. Mariani, E. Maljaars, Matteo Agostini, Lorenzo Frassinetti, S. E. Sharapov, C.K. Tsui, Vladimir E. Moiseenko, Robert Mumgaard, Amanda Hubbard, L. Pigatto, F. Matos, D. S. Gahle, Roberto Maurizio, I. Voitsekhovitch, Paolo Zanca, J. Buermans, A. Fil, T. Lunt, S. S. Henderson, D. Ricci, M. Kong, Ondrej Ficker, Matthias Wiesenberger, L. Cordaro, P. Innocente, Roberto Paccagnella, Benoit Labit, N. Rispoli, M. Rabinski, G. F. Harrer, Roch Kwiatkowski, A. Moro, A. A. Beletskii, M. Vallar, M. Reich, F. Reimold, P. Piovesan, Mirko Salewski, J. Hawke, Giuseppe Gorini, J. Čeřovský, F. Causa, H. Reimerdes, B. Esposito, Jernej Kovacic, P. V. Kazantzidis, H. Anand, Gergely Papp, M. Valisa, K. Mitosinkova, Vlado Menkovski, F. Bombarda, M. Fontana, Tommaso Bolzonella, Pascale Hennequin, T. Gyergyek, D. L. Keeling, T. Eich, M. Garcia-Munoz, Stefano Alberti, P. Blanchard, F. Bouquey, R. Shousha, M. Scheffer, B. S. Schneider, R. Jacquier, D. Choi, Nick Walkden, Ola Embréus, C. Ionita Schrittwieser, S. Saarelma, J. Garcia, M. G. Dunne, M. Tomes, R. Zagórski, Y. R. Martin, A. Kappatou, B. P. Duval, T. Tala, Swiss National Science Foundation, Universita degli studi di Napoli 'Parthenope' [Napoli], Max-Planck-Institut für Plasmaphysik [Garching] (IPP), Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Istituto di Fisica del Plasma, EURATOM-ENEA-CNR Association, Consiglio Nazionale delle Ricerche [Roma] (CNR), Physique des interactions ioniques et moléculaires (PIIM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Ecole Polytechnique Fédérale de Lausanne (EPFL), Centre de Recherches en Physique des Plasmas (CRPP), Department of Physics [Stockholm], Stockholm University, Laboratoire de Physique des Plasmas (LPP), Université Paris-Sud - Paris 11 (UP11)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École polytechnique (X)-Sorbonne Université (SU)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), EURATOM/CCFE Fusion Association, Culham Science Centre [Abingdon], York Plasma Institute (YPI), University of York [York, UK], Faculty of Mathematics and Physics [Praha/Prague], Charles University [Prague] (CU), Association EURATOM-CEA (CEA/DSM/DRFC), University College Cork (UCC), Department of Mechanical and Manufacturing Engineering [Aalborg] (M-TECH), Aalborg University [Denmark] (AAU), Università degli Studi di Milano-Bicocca [Milano] (UNIMIB), Instituto de Plasmas e Fusão Nuclear [Lisboa] (IPFN), Instituto Superior Técnico, Universidade Técnica de Lisboa (IST), Université Paris-Saclay-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-École polytechnique (X)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Coda, S, Agostini, M, Albanese, R, Alberti, S, Alessi, E, Allan, S, Allcock, J, Ambrosino, R, Anand, H, Andrebe, Y, Arnichand, H, Auriemma, F, Ayllon-Guerola, J, Bagnato, F, Ball, J, Baquero-Ruiz, M, Beletskii, A, Bernert, M, Bin, W, Blanchard, P, Blanken, T, Boedo, J, Bogar, O, Bolzonella, T, Bombarda, F, Bonanomi, N, Bouquey, F, Bowman, C, Brida, D, Bucalossi, J, Buermans, J, Bufferand, H, Buratti, P, Calabro, G, Calacci, L, Camenen, Y, Carnevale, D, Carpanese, F, Carr, M, Carraro, L, Casolari, A, Causa, F, Cerovsky, J, Chellai, O, Chmielewski, P, Choi, D, Christen, N, Ciraolo, G, Cordaro, L, Costea, S, Cruz, N, Czarnecka, A, Dal Molin, A, David, P, Decker, J, De Oliveira, H, Douai, D, Dreval, M, Dudson, B, Dunne, M, Duval, B, Eich, T, Elmore, S, Embreus, O, Esposito, B, Faitsch, M, Farnik, M, Fasoli, A, Fedorczak, N, Felici, F, Feng, S, Feng, X, Ferro, G, Fevrier, O, Ficker, O, Fil, A, Fontana, M, Frassinetti, L, Furno, I, Gahle, D, Galassi, D, Galazka, K, Gallo, A, Galperti, C, Garavaglia, S, Garcia, J, Garcia-Munoz, M, Garrido, A, Garrido, I, Gath, J, Geiger, B, Giruzzi, G, Gobbin, M, Goodman, T, Gorini, G, Gospodarczyk, M, Granucci, G, Graves, J, Gruca, M, Gyergyek, T, Hakola, A, Happel, T, Harrer, G, Harrison, J, Havlickova, E, Hawke, J, Henderson, S, Hennequin, P, Hesslow, L, Hogeweij, D, Hogge, J, Hopf, C, Hoppe, M, Horacek, J, Huang, Z, Hubbard, A, Iantchenko, A, Igochine, V, Innocente, P, Ionita Schrittwieser, C, Isliker, H, Jacquier, R, Jardin, A, Kappatou, A, Karpushov, A, Kazantzidis, P, Keeling, D, Kirneva, N, Komm, M, Kong, M, Kovacic, J, Krawczyk, N, Kudlacek, O, Kurki-Suonio, T, Kwiatkowski, R, Labit, B, Lazzaro, E, Linehan, B, Lipschultz, B, Llobet, X, Lombroni, R, Loschiavo, V, Lunt, T, Macusova, E, Madsen, J, Maljaars, E, Mantica, P, Maraschek, M, Marchetto, C, Marco, A, Mariani, A, Marini, C, Martin, Y, Matos, F, Frisina, M, Mavkov, B, Mazon, D, Mccarthy, P, Mcdermott, R, Menkovski, V, Merle, A, Meyer, H, Micheletti, D, Militello, F, Mitosinkova, K, Mlynar, J, Moiseenko, V, Molina Cabrera, P, Morales, J, Moret, J, Moro, A, Mumgaard, R, Naulin, V, Nem, R, Nespoli, F, Nielsen, A, Nielsen, S, Nocente, M, Nowak, S, Offeddu, N, Orsitto, F, Paccagnella, R, Palha, A, Papp, G, Pau, A, Pavlichenko, R, Perek, A, Pericoli Ridolfini, V, Pesamosca, F, Piergotti, V, Pigatto, L, Piovesan, P, Piron, C, Plyusnin, V, Poli, E, Porte, L, Pucella, G, Puiatti, M, Putterich, T, Rabinski, M, Juul Rasmussen, J, Ravensbergen, T, Reich, M, Reimerdes, H, Reimold, F, Reux, C, Ricci, D, Ricci, P, Rispoli, N, Rosato, J, Saarelma, S, Salewski, M, Salmi, A, Sauter, O, Scheffer, M, Schlatter, C, Schneider, B, Schrittwieser, R, Sharapov, S, Sheeba, R, Sheikh, U, Shousha, R, Silva, M, Sinha, J, Sozzi, C, Spolaore, M, Stipani, L, Strand, P, Tala, T, Tema Biwole, A, Teplukhina, A, Testa, D, Theiler, C, Thornton, A, Tomaz, G, Tomes, M, Tran, M, Tsironis, C, Tsui, C, Urban, J, Valisa, M, Vallar, M, Van Vugt, D, Vartanian, S, Vasilovici, O, Verhaegh, K, Vermare, L, Vianello, N, Viezzer, E, Vijvers, W, Villone, F, Voitsekhovitch, I, Vu, N, Walkden, N, Wauters, T, Weiland, M, Weisen, H, Wensing, M, Wiesenberger, M, Wilkie, G, Wischmeier, M, Wu, K, Yoshida, M, Zagorski, R, Zanca, P, Zebrowski, J, Zisis, A, Zuin, M, Università degli Studi di Napoli 'Parthenope' = University of Naples (PARTHENOPE), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École polytechnique (X)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Université Paris-Sud - Paris 11 (UP11)-Observatoire de Paris, Coda, S., Agostini, M., Albanese, R., Alberti, S., Alessi, E., Allan, S., Allcock, J., Ambrosino, R., Anand, H., Andrebe, Y., Arnichand, H., Auriemma, F., Ayllon-Guerola, J. M., Bagnato, F., Ball, J., Baquero-Ruiz, M., Beletskii, A. A., Bernert, M., Bin, W., Blanchard, P., Blanken, T. C., Boedo, J. A., Bogar, O., Bolzonella, T., Bombarda, F., Bonanomi, N., Bouquey, F., Bowman, C., Brida, D., Bucalossi, J., Buermans, J., Bufferand, H., Buratti, P., Calabro, G., Calacci, L., Camenen, Y., Carnevale, D., Carpanese, F., Carr, M., Carraro, L., Casolari, A., Causa, F., Cerovsky, J., Chellai, O., Chmielewski, P., Choi, D., Christen, N., Ciraolo, G., Cordaro, L., Costea, S., Cruz, N., Czarnecka, A., Dal Molin, A., David, P., Decker, J., De Oliveira, H., Douai, D., Dreval, M. B., Dudson, B., Dunne, M., Duval, B. P., Eich, T., Elmore, S., Embreus, O., Esposito, B., Faitsch, M., Farnik, M., Fasoli, A., Fedorczak, N., Felici, F., Feng, S., Feng, X., Ferro, G., Fevrier, O., Ficker, O., Fil, A., Fontana, M., Frassinetti, L., Furno, I., Gahle, D. S., Galassi, D., Galazka, K., Gallo, A., Galperti, C., Garavaglia, S., Garcia, J., Garcia-Munoz, M., Garrido, A. J., Garrido, I., Gath, J., Geiger, B., Giruzzi, G., Gobbin, M., Goodman, T. P., Gorini, G., Gospodarczyk, M., Granucci, G., Graves, J. P., Gruca, M., Gyergyek, T., Hakola, A., Happel, T., Harrer, G. F., Harrison, J., Havlickova, E., Hawke, J., Henderson, S., Hennequin, P., Hesslow, L., Hogeweij, D., Hogge, J. -P., Hopf, C., Hoppe, M., Horacek, J., Huang, Z., Hubbard, A., Iantchenko, A., Igochine, V., Innocente, P., Ionita Schrittwieser, C., Isliker, H., Jacquier, R., Jardin, A., Kappatou, A., Karpushov, A., Kazantzidis, P. -V., Keeling, D., Kirneva, N., Komm, M., Kong, M., Kovacic, J., Krawczyk, N., Kudlacek, O., Kurki-Suonio, T., Kwiatkowski, R., Labit, B., Lazzaro, E., Linehan, B., Lipschultz, B., Llobet, X., Lombroni, R., Loschiavo, V. P., Lunt, T., Macusova, E., Madsen, J., Maljaars, E., Mantica, P., Maraschek, M., Marchetto, C., Marco, A., Mariani, A., Marini, C., Martin, Y., Matos, F., Maurizio, R., Mavkov, B., Mazon, D., Mccarthy, P., Mcdermott, R., Menkovski, V., Merle, A., Meyer, H., Micheletti, D., Militello, F., Mitosinkova, K., Mlynar, J., Moiseenko, V., Molina Cabrera, P. A., Morales, J., Moret, J. -M., Moro, A., Mumgaard, R. T., Naulin, V., Nem, R. D., Nespoli, F., Nielsen, A. H., Nielsen, S. K., Nocente, M., Nowak, S., Offeddu, N., Orsitto, F. P., Paccagnella, R., Palha, A., Papp, G., Pau, A., Pavlichenko, R. O., Perek, A., Pericoli Ridolfini, V., Pesamosca, F., Piergotti, V., Pigatto, L., Piovesan, P., Piron, C., Plyusnin, V., Poli, E., Porte, L., Pucella, G., Puiatti, M. E., Putterich, T., Rabinski, M., Juul Rasmussen, J., Ravensbergen, T., Reich, M., Reimerdes, H., Reimold, F., Reux, C., Ricci, D., Ricci, P., Rispoli, N., Rosato, J., Saarelma, S., Salewski, M., Salmi, A., Sauter, O., Scheffer, M., Schlatter, C., Schneider, B. S., Schrittwieser, R., Sharapov, S., Sheeba, R. R., Sheikh, U., Shousha, R., Silva, M., Sinha, J., Sozzi, C., Spolaore, M., Stipani, L., Strand, P., Tala, T., Tema Biwole, A. S., Teplukhina, A. A., Testa, D., Theiler, C., Thornton, A., Tomaz, G., Tomes, M., Tran, M. Q., Tsironis, C., Tsui, C. K., Urban, J., Valisa, M., Vallar, M., Van Vugt, D., Vartanian, S., Vasilovici, O., Verhaegh, K., Vermare, L., Vianello, N., Viezzer, E., Vijvers, W. A. J., Villone, F., Voitsekhovitch, I., Vu, N. M. T., Walkden, N., Wauters, T., Weiland, M., Weisen, H., Wensing, M., Wiesenberger, M., Wilkie, G., Wischmeier, M., Wu, K., Yoshida, M., Zagorski, R., Zanca, P., Zebrowski, J., Zisis, A., Zuin, M., Coda, S. et al, Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear., Universidad de Sevilla, Departamento de Ingeniería Mecánica y Fabricación, Universidad de Sevilla. TEP111: Ingeniería Mecánica, Universidad de Sevilla. RNM138: Física Nuclear Aplicada, EUROfusion MST1 Team, Control Systems Technology, Data Mining, Science and Technology of Nuclear Fusion, and Magneto-Hydro-Dynamic Stability of Fusion Plasmas

Subjects
Nuclear and High Energy Physics, Tokamak, Settore ING-INF/04, TK, UPGRADE, Cyclotron, Overview, Cyclotron resonance, overview, CONFINEMENT, DETACHMENT, 7. Clean energy, 01 natural sciences, 010305 fluids & plasmas, law.invention, law, [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], CONTROL-SYSTEM, 0103 physical sciences, EUROfusion, 010306 general physics, tokamak, QC, plasma, nuclear fusion, Physics, PLASMA, Divertor, Magnetic confinement fusion, Plasma, Mechanics, TCV, MST1, Condensed Matter Physics, Neutral beam injection, Physics and Astronomy, 13. Climate action, confinement, detachment, Nuclear fusion, control-system, upgrade, TCV, MST1, Beam (structure), Tokamaks
Abstract

The research program of the TCV tokamak ranges from conventional to advanced-tokamak scenarios and alternative divertor configurations, to exploratory plasmas driven by theoretical insight, exploiting the device's unique shaping capabilities. Disruption avoidance by real-time locked mode prevention or unlocking with electron-cyclotron resonance heating (ECRH) was thoroughly documented, using magnetic and radiation triggers. Runaway generation with high-Z noble-gas injection and runaway dissipation by subsequent Ne or Ar injection were studied for model validation. The new 1 MW neutral beam injector has expanded the parameter range, now encompassing ELMy H-modes in an ITER-like shape and nearly non-inductive H-mode discharges sustained by electron cyclotron and neutral beam current drive. In the H-mode, the pedestal pressure increases modestly with nitrogen seeding while fueling moves the density pedestal outwards, but the plasma stored energy is largely uncorrelated to either seeding or fueling. High fueling at high triangularity is key to accessing the attractive small edge-localized mode (type-II) regime. Turbulence is reduced in the core at negative triangularity, consistent with increased confinement and in accord with global gyrokinetic simulations. The geodesic acoustic mode, possibly coupled with avalanche events, has been linked with particle flow to the wall in diverted plasmas. Detachment, scrape-off layer transport, and turbulence were studied in L- and H-modes in both standard and alternative configurations (snowflake, super-X, and beyond). The detachment process is caused by power 'starvation' reducing the ionization source, with volume recombination playing only a minor role. Partial detachment in the H-mode is obtained with impurity seeding and has shown little dependence on flux expansion in standard single-null geometry. In the attached L-mode phase, increasing the outer connection length reduces the in-out heat-flow asymmetry. A doublet plasma, featuring an internal X-point, was achieved successfully, and a transport barrier was observed in the mantle just outside the internal separatrix. In the near future variable-configuration baffles and possibly divertor pumping will be introduced to investigate the effect of divertor closure on exhaust and performance, and 3.5 MW ECRH and 1 MW neutral beam injection heating will be added., This work was supported in part by the Swiss National Science Foundation.

Published
2019

43. Dependence on plasma shape and plasma fueling for small edge-localized mode regimes in TCV and ASDEX Upgrade

Author

V. Piergotti, F. Pesamosca, Bogdan Hnat, A. Sperduti, A. Krivska, J. Vicente, Panagiotis Tolias, Emanuele Poli, Matthias Hoelzl, Benedikt Geiger, A. Jardin, J. Ayllon-Guerola, G. Apruzzese, T. Lunt, J. Galdon-Quiroga, Riccardo Maggiora, M. Tardocchi, M. Koubiti, T. Jonsson, Bruce Lipschultz, P. Innocente, A. Gude, I Miron, M. G. Dunne, G. F. Harrer, A. Moro, A. Iantchenko, K. Galazka, P. Poloskei, K. Bogar, Roberto Ambrosino, G. Ferr, Vladimir E. Moiseenko, Istvan Cziegler, L. Guimarais, S. Vartanian, B. Erds, G. Pucella, V. Bobkov, James Buchanan, Raffaele Albanese, Harry M. Meyer, D. Boeyaert, G. F. Matthews, Eva Macusova, V. S. Marchenko, R. Zagórski, J. Buermans, A. Fil, W. Zhang, Giuseppe Gorini, B. Tal, D. Zaloga, Hugo Bufferand, A. Romano, L. Colas, J. Zebrowski, M. Weiland, L. Barrera-Orte, Matjaž Panjan, A.J. Thornton, E. Wolfrum, Miglena Dimitrova, R. M. McDermott, R. Lombroni, O. Tudisco, F. Reimold, E. R. Solano, X. Feng, Petra Bilkova, M. Groth, E. Alessi, D. S. Gahle, Olivier Février, I. Voitsekhovitch, Matthew Carr, A. Bock, O. Vasilovici, C. Ham, Lorenzo Figini, Guglielmo Rubinacci, Peter Lang, Pierre Manas, S. Costea, A. Kirk, F. Causa, J. Adamek, Vu N. M. T., M. Cavedon, O. Grover, Geert Verdoolaege, M. Spolaore, L. Sanchis-Sanchez, P. Bohm, P. V. Kazantzidis, Sarah Newton, M. Tomes, M.-L. Mayoral, J. R. Harrison, C. Mazzotta, H. Reimerdes, Jorge Morales, D. Brunetti, J. Gonzalez-Martin, Tomas Markovic, S. S. Henderson, D. Ricci, J. Juul Rasmussen, F. Janky, S. Saarelma, Z. Popovic, C. Tsironis, J. J. Rasmussen, S. K. Hansen, Sandra C. Chapman, Volker Naulin, H. Arnichand, Roberto Paccagnella, M. Faitsch, Anders Nielsen, M. Kong, V. Igochine, C. Piron, C. Bowman, Jorge Ferreira, D. Sytnykov, K. G. McClements, Olivier Sauter, Ondrej Ficker, Matthias Wiesenberger, T. Ravensbergen, C. Reux, Irena Ivanova-Stanik, Dirk Reiser, M. Bernert, M. Vallar, J-M Moret, M. Gruca, D. I. Refy, P. Cano Megias, Benoit Labit, M. Schubert, Giuliana Sias, O. Bogar, P. J. Mc Carthy, I. Faust, Gergely Papp, F. Matos, J. Garcia, C. Marini, E. L. Sorokovoy, Dimitri Voltolina, George Wilkie, J. M. Santos, R. R. Sheeba, Vladimir Weinzettl, Sergei Kasilov, J. Cerovsky, Matteo Agostini, G. Tardini, Laurie Porte, F. Dolizy, L. Gil, Matthias Komm, A. Dal Molin, B. Sieglin, Roch Kwiatkowski, M. C. C Messmer, Toke Koldborg Jensen, Vinodh Bandaru, Ben F. McMillan, Alessandra Fanni, Daniele Carnevale, Shimpei Futatani, D. P. Coster, V. Korovin, S. E. Sharapov, Patrik Ollus, J. Gath, A. Czarnecka, D. Gallart, M. Peterka, P. Vallejos Olivares, Jernej Kovacic, Nicolas Fedorczak, Silvio Ceccuzzi, L. Piron, J. Rosato, G. Kocsis, Stefan Kragh Nielsen, M. Garcia-Mu oz, Radomir Panek, S. F. Smith, Paolo Bettini, A. Mariani, R. Dejarnac, Lorenzo Frassinetti, D. Douai, L. Garzotti, H. J. Sun, C.K. Tsui, N. den Harder, John Elmerdahl Olsen, F. Bombarda, M. Francesco, Piero Martin, D. Hogeweij, P. Blanchard, F. Bouquey, Gabor Por, Luca Boncagni, Carlo Sozzi, Martin Hron, P. A. Schneider, V. P. Loschiavo, David Terranova, D. Aguiam, D. Choi, M. Gobbin, D. Iglesias, M. Reich, G. Avdeeva, A. Gallo, O. Biletskyi, M. Aradi, F. Liu, M. Griener, Antti Snicker, L. Kripner, Jérôme Bucalossi, L. Hesslow, Nick Walkden, M. Rodriguez-Ramos, T. C. Blanken, Cristian Galperti, F. Jaulmes, G. Calabr, G.A. Rattá, W. Bin, S. Garavaglia, V. Plyusnin, Andreas Frank Martitsch, A. Zisis, Rita Lorenzini, Duccio Testa, M. Passeri, Ola Embréus, N. Krawczyk, K. Särkimäki, Davide Galassi, D. Samaddar, M. Oberkofler, E. Seliunin, D. Brida, P. Buratti, F. Nabais, J. Ongena, J. Likonen, Yann Camenen, M. J. Mantsinen, F. Carpanese, S. Wiesen, P. Piovesan, Mirko Salewski, J. Hawke, Florian Laggner, R. Bilato, M. Wischmeier, L. Pigatto, G. I. Pokol, G. Giruzzi, Jens Madsen, D. Gadariya, L. Stipani, Christian Theiler, J. Stober, Michael Barnes, Timothy Goodman, R. D. Nem, J. J. Dominguez-Palacios Duran, F. Militello, Y. 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Wu, Anna Salmi, F. Nespoli, S. Elmore, O. Kudlacek, A. Kallenbach, Rok Zaplotnik, D. L. Keeling, L. Giannone, M. Maraschek, Carlos B. da Silva, F. Hitzler, M. Valovic, M. W. Jakubowski, L. Gabellieri, Jozef Varju, Marco Cecconello, M. Valisa, Vlado Menkovski, Gábor Cseh, E. Thoren, T. Eich, R. Coelho, F. Bagnato, Matteo Zuin, Alexander Kendl, G. Rocchi, G. Pautasso, D. Naydenkova, R. O. Pavlichenko, M. Fontana, Lionello Marrelli, Tommaso Bolzonella, Nicola Vianello, Pascale Hennequin, R. Ochoukov, Tom Wauters, Christian Hopf, Ch. Fuchs, E. Giovannozzi, Fulvio Auriemma, Roberto Maurizio, Stefan Buller, Massimo Nocente, K. Krieger, G. Grenfell, N. Rispoli, R. Dux, Barbara Cannas, Laboratoire de Physique des Plasmas (LPP), Université Paris-Saclay-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-École polytechnique (X)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Labit, B., Eich, T., Harrer, G. F., Wolfrum, E., Bernert, M., Dunne, M. G., Frassinetti, L., Hennequin, P., Maurizio, R., Merle, A., Meyer, H., Saarelma, S., Sheikh, U., Adamek, J., Agostini, M., Aguiam, D., Akers, R., Albanese, R., Albert, C., Alessi, E., Ambrosino, R., Andr be, Y., Angioni, C., Apruzzese, G., Aradi, M., Arnichand, H., Auriemma, F., Avdeeva, G., Ayllon-Guerola, J. M., Bagnato, F., Bandaru, V. K., Barnes, M., Barrera-Orte, L., Bettini, P., Bilato, R., Biletskyi, O., Bilkova, P., Bin, W., Blanchard, P., Blanken, T., Bobkov, V., Bock, A., Boeyaert, D., Bogar, K., Bogar, O., Bohm, P., Bolzonella, T., Bombarda, F., Boncagni, L., Bouquey, F., Bowman, C., Brezinsek, S., Brida, D., Brunetti, D., Bucalossi, J., Buchanan, J., Buermans, J., Bufferand, H., Buller, S., Buratti, P., Burckhart, A., Calabr, G., Calacci, L., Camenen, Y., Cannas, B., Cano Megias, P., Carnevale, D., Carpanese, F., Carr, M., Carralero, D., Carraro, L., Casolari, A., Cathey, A., Causa, F., Cavedon, M., Cecconello, M., Ceccuzzi, S., Cerovsky, J., Chapman, S., Chmielewski, P., Choi, D., Cianfarani, C., Ciraolo, G., Coda, S., Coelho, R., Colas, L., Colette, D., Cordaro, L., Cordella, F., Costea, S., Coster, D., Cruz Zabala, D. J., Cseh, G., Czarnecka, A., Cziegler, I., D'Arcangelo, O., Dal Molin, A., David, P., De Carolis, G., De Oliveira, H., Decker, J., Dejarnac, R., Delogu, R., Den Harder, N., Dimitrova, M., Dolizy, F., Dominguez-Palacios Duran, J. J., Douai, D., Drenik, A., Dreval, M., Dudson, B., Dunai, D., Duval, B. P., Dux, R., Elmore, S., Embreus, O., Erds, B., Fable, E., Faitsch, M., Fanni, A., Farnik, M., Faust, I., Faustin, J., Fedorczak, N., Felici, F., Feng, S., Feng, X., Ferreira, J., Ferr, G., Fevrier, O., Ficker, O., Figini, L., Figueiredo, A., Fil, A., Fontana, M., Francesco, M., Fuchs, C., Futatani, S., Gabellieri, L., Gadariya, D., Gahle, D., Galassi, D., Galazka, K., Galdon-Quiroga, J., Galeani, S., Gallart, D., Gallo, A., Galperti, C., Garavaglia, S., Garcia, J., Garcia-Lopez, J., Garcia-Mu oz, M., Garzotti, L., Gath, J., Geiger, B., Giacomelli, L., Giannone, L., Gibson, S., Gil, L., Giovannozzi, E., Giruzzi, G., Gobbin, M., Gonzalez-Martin, J., Goodman, T. P., Gorini, G., Gospodarczyk, M., Granucci, G., Grekov, D., Grenfell, G., Griener, M., Groth, M., Grover, O., Gruca, M., Gude, A., Guimarais, L., Gyergyek, T., Hacek, P., Hakola, A., Ham, C., Happel, T., Harrison, J., Havranek, A., Hawke, J., Henderson, S., Hesslow, L., Hitzler, F., Hnat, B., Hobirk, J., Hoelzl, M., Hogeweij, D., Hopf, C., Hoppe, M., Horacek, J., Hron, M., Huang, Z., Iantchenko, A., Iglesias, D., Igochine, V., Innocente, P., Ionita-Schrittwieser, C., Isliker, H., Ivanova-Stanik, I., Jacobsen, A., Jakubowski, M., Janky, F., Jardin, A., Jaulmes, F., Jensen, T., Jonsson, T., Kallenbach, A., Kappatou, A., Karpushov, A., Kasilov, S., Kazakov, Y., Kazantzidis, P. V., Keeling, D., Kelemen, M., Kendl, A., Kernbichler, W., Kirk, A., Kocsis, G., Komm, M., Kong, M., Korovin, V., Koubiti, M., Kovacic, J., Krawczyk, N., Krieger, K., Kripner, L., Krivska, A., Kudlacek, O., Kulyk, Y., Kurki-Suonio, T., Kwiatkowski, R., Laggner, F., Laguardia, L., Lahtinen, A., Lang, P., Likonen, J., Lipschultz, B., Liu, F., Lombroni, R., Lorenzini, R., Loschiavo, V. P., Lunt, T., Macusova, E., Madsen, J., Maggiora, R., Maljaars, B., Manas, P., Mantica, P., Mantsinen, M. J., Manz, P., Maraschek, M., Marchenko, V., Marchetto, C., Mariani, A., Marini, C., Markovic, T., Marrelli, L., Martin, P., Martin Solis, J. R., Martitsch, A., Mastrostefano, S., Matos, F., Matthews, G., Mayoral, M. -L., Mazon, D., Mazzotta, C., Mc Carthy, P., Mcclements, K., Mcdermott, R., Mcmillan, B., Meineri, C., Menkovski, V., Meshcheriakov, D., Messmer, M., Micheletti, D., Milanesio, D., Militello, F., Miron, I. G., Mlynar, J., Moiseenko, V., Molina Cabrera, P. A., Morales, J., Moret, J. -M., Moro, A., Moulton, D., Nabais, F., Naulin, V., Naydenkova, D., Nem, R. D., Nespoli, F., Newton, S., Nielsen, A. H., Nielsen, S. K., Nikolaeva, V., Nocente, M., Nowak, S., Oberkofler, M., Ochoukov, R., Ollus, P., Olsen, J., Omotani, J., Ongena, J., Orain, F., Orsitto, F. P., Paccagnella, R., Palha, A., Panaccione, L., Panek, R., Panjan, M., Papp, G., Paradela Perez, I., Parra, F., Passeri, M., Pau, A., Pautasso, G., Pavlichenko, R., Perek, A., Pericoli Radolfini, V., Pesamosca, F., Peterka, M., Petrzilka, V., Piergotti, V., Pigatto, L., Piovesan, P., Piron, C., Piron, L., Plyusnin, V., Pokol, G., Poli, E., Poloskei, P., Popov, T., Popovic, Z., Por, G., Porte, L., Pucella, G., Puiatti, M. E., Putterich, T., Rabinski, M., Juul Rasmussen, J., Rasmussen, J., Ratta, G. A., Ratynskaia, S., Ravensbergen, T., Refy, D., Reich, M., Reimerdes, H., Reimold, F., Reiser, D., Reux, C., Reznik, S., Ricci, D., Rispoli, N., Rivero-Rodriguez, J. F., Rocchi, G., Rodriguez-Ramos, M., Romano, A., Rosato, J., Rubinacci, G., Rubino, G., Ryan, D. A., Salewski, M., Salmi, A., Samaddar, D., Sanchis-Sanchez, L., Santos, J., Sarkimaki, K., Sassano, M., Sauter, O., Scannell, R., Scheffer, M., Schneider, B. S., Schneider, P., Schrittwieser, R., Schubert, M., Seidl, J., Seliunin, E., Sharapov, S., Sheeba, R. R., Sias, G., Sieglin, B., Silva, C., Sipila, S., Smith, S., Snicker, A., Solano, E. R., Hansen, S. K., Soria-Hoyo, C., Sorokovoy, E., Sozzi, C., Sperduti, A., Spizzo, G., Spolaore, M., Stejner, M., Stipani, L., Stober, J., Strand, P., Sun, H., Suttrop, W., Sytnykov, D., Szepesi, T., Tal, B., Tala, T., Tardini, G., Tardocchi, M., Teplukhina, A., Terranova, D., Testa, D., Theiler, C., Thoren, E., Thornton, A., Tilia, B., Tolias, P., Tomes, M., Toscano-Jimenez, M., Tsironis, C., Tsui, C., Tudisco, O., Urban, J., Valisa, M., Vallar, M., Vallejos Olivares, P., Valovic, M., Van Vugt, D., Vanovac, B., Varje, J., Varju, J., Varoutis, S., Vartanian, S., Vasilovici, O., Vega, J., Verdoolaege, G., Verhaegh, K., Vermare, L., Vianello, N., Vicente, J., Viezzer, E., Villone, F., Voitsekhovitch, I., Voltolina, D., Vondracek, P., Vu, N. M. T., Walkden, N., Wauters, T., Weiland, M., Weinzettl, V., Wensing, M., Wiesen, S., Wiesenberger, M., Wilkie, G., Willensdorfer, M., Wischmeier, M., Wu, K., Xiang, L., Zagorski, R., Zaloga, D., Zanca, P., Zaplotnik, R., Zebrowski, J., Zhang, W., Zisis, A., Zoletnik, S., Zuin, M., Swiss Federal Institute of Technology Lausanne, Max-Planck-Institut für Plasmaphysik, Vienna University of Technology, KTH Royal Institute of Technology, Université Paris-Saclay, JET, Czech Academy of Sciences, National Research Council of Italy, University of Lisbon, University of Naples Federico II, Graz University of Technology, University of Naples Parthenope, Agenzia nazionale per le nuove tecnologie, l'energia e lo sviluppo economico sostenibile, Danmarks Tekniske Universitet, University of Seville, University of Oxford, EUROfusion Programme Management Unit, National Science Center Kharkov Institute of Physics and Technology, Eindhoven University of Technology, Forschungszentrum Jülich, CEA, University of York, Royal Military Academy, Chalmers University of Technology, Tuscia University, Università di Roma Tor Vergata, CNRS, University of Cagliari, CIEMAT, Uppsala University, University of Warwick, Soltan Institute for Nuclear Studies, University of Innsbruck, Hungarian Academy of Sciences, Budapest University of Technology and Economics, Durham University, BarcelonaTech, University of Strathclyde, Barcelona Supercomputing Center, University of Milan - Bicocca, Karlsruhe Institute of Technology, Fusion and Plasma Physics, J. Stefan Institute, VTT Technical Research Centre of Finland, Dutch Institute for Fundamental Energy Research, Aristotle University of Thessaloniki, National Technical University of Athens, National Centre for Nuclear Research, University of Helsinki, Université Côte d'Azur, Polytechnic University of Turin, NASU - Institute of Nuclear Research, University of Cassino and Southern Lazio, University College Cork, National Institute for Laser, Plasma and Radiation Physics, Department of Applied Physics, Sofia University St. Kliment Ohridski, Ghent University, Aalto-yliopisto, Aalto University, Labit, B, Eich, T, Harrer, G, Wolfrum, E, Bernert, M, Dunne, M, Frassinetti, L, Hennequin, P, Maurizio, R, Merle, A, Meyer, H, Saarelma, S, Sheikh, U, Adamek, J, Agostini, M, Aguiam, D, Akers, R, Albanese, R, Albert, C, Alessi, E, Ambrosino, R, Andr be, Y, Angioni, C, Apruzzese, G, Aradi, M, Arnichand, H, Auriemma, F, Avdeeva, G, Ayllon-Guerola, J, Bagnato, F, Bandaru, V, Barnes, M, Barrera-Orte, L, Bettini, P, Bilato, R, Biletskyi, O, Bilkova, P, Bin, W, Blanchard, P, Blanken, T, Bobkov, V, Bock, A, Boeyaert, D, Bogar, K, Bogar, O, Bohm, P, Bolzonella, T, Bombarda, F, Boncagni, L, Bouquey, F, Bowman, C, Brezinsek, S, Brida, D, Brunetti, D, Bucalossi, J, Buchanan, J, Buermans, J, Bufferand, H, Buller, S, Buratti, P, Burckhart, A, Calabr, G, Calacci, L, Camenen, Y, Cannas, B, Cano Megias, P, Carnevale, D, Carpanese, F, Carr, M, Carralero, D, Carraro, L, Casolari, A, Cathey, A, Causa, F, Cavedon, M, Cecconello, M, Ceccuzzi, S, Cerovsky, J, Chapman, S, Chmielewski, P, Choi, D, Cianfarani, C, Ciraolo, G, Coda, S, Coelho, R, Colas, L, Colette, D, Cordaro, L, Cordella, F, Costea, S, Coster, D, Cruz Zabala, D, Cseh, G, Czarnecka, A, Cziegler, I, D'Arcangelo, O, Dal Molin, A, David, P, De Carolis, G, De Oliveira, H, Decker, J, Dejarnac, R, Delogu, R, Den Harder, N, Dimitrova, M, Dolizy, F, Dominguez-Palacios Duran, J, Douai, D, Drenik, A, Dreval, M, Dudson, B, Dunai, D, Duval, B, Dux, R, Elmore, S, Embreus, O, Erds, B, Fable, E, Faitsch, M, Fanni, A, Farnik, M, Faust, I, Faustin, J, Fedorczak, N, Felici, F, Feng, S, Feng, X, Ferreira, J, Ferr, G, Fevrier, O, Ficker, O, Figini, L, Figueiredo, A, Fil, A, Fontana, M, Francesco, M, Fuchs, C, Futatani, S, Gabellieri, L, Gadariya, D, Gahle, D, Galassi, D, Galazka, K, Galdon-Quiroga, J, Galeani, S, Gallart, D, Gallo, A, Galperti, C, Garavaglia, S, Garcia, J, Garcia-Lopez, J, Garcia-Mu oz, M, Garzotti, L, Gath, J, Geiger, B, Giacomelli, L, Giannone, L, Gibson, S, Gil, L, Giovannozzi, E, Giruzzi, G, Gobbin, M, Gonzalez-Martin, J, Goodman, T, Gorini, G, Gospodarczyk, M, Granucci, G, Grekov, D, Grenfell, G, Griener, M, Groth, M, Grover, O, Gruca, M, Gude, A, Guimarais, L, Gyergyek, T, Hacek, P, Hakola, A, Ham, C, Happel, T, Harrison, J, Havranek, A, Hawke, J, Henderson, S, Hesslow, L, Hitzler, F, Hnat, B, Hobirk, J, Hoelzl, M, Hogeweij, D, Hopf, C, Hoppe, M, Horacek, J, Hron, M, Huang, Z, Iantchenko, A, Iglesias, D, Igochine, V, Innocente, P, Ionita-Schrittwieser, C, Isliker, H, Ivanova-Stanik, I, Jacobsen, A, Jakubowski, M, Janky, F, Jardin, A, Jaulmes, F, Jensen, T, Jonsson, T, Kallenbach, A, Kappatou, A, Karpushov, A, Kasilov, S, Kazakov, Y, Kazantzidis, P, Keeling, D, Kelemen, M, Kendl, A, Kernbichler, W, Kirk, A, Kocsis, G, Komm, M, Kong, M, Korovin, V, Koubiti, M, Kovacic, J, Krawczyk, N, Krieger, K, Kripner, L, Krivska, A, Kudlacek, O, Kulyk, Y, Kurki-Suonio, T, Kwiatkowski, R, Laggner, F, Laguardia, L, Lahtinen, A, Lang, P, Likonen, J, Lipschultz, B, Liu, F, Lombroni, R, Lorenzini, R, Loschiavo, V, Lunt, T, Macusova, E, Madsen, J, Maggiora, R, Maljaars, B, Manas, P, Mantica, P, Mantsinen, M, Manz, P, Maraschek, M, Marchenko, V, Marchetto, C, Mariani, A, Marini, C, Markovic, T, Marrelli, L, Martin, P, Martin Solis, J, Martitsch, A, Mastrostefano, S, Matos, F, Matthews, G, Mayoral, M, Mazon, D, Mazzotta, C, Mc Carthy, P, Mcclements, K, Mcdermott, R, Mcmillan, B, Meineri, C, Menkovski, V, Meshcheriakov, D, Messmer, M, Micheletti, D, Milanesio, D, Militello, F, Miron, I, Mlynar, J, Moiseenko, V, Molina Cabrera, P, Morales, J, Moret, J, Moro, A, Moulton, D, Nabais, F, Naulin, V, Naydenkova, D, Nem, R, Nespoli, F, Newton, S, Nielsen, A, Nielsen, S, Nikolaeva, V, Nocente, M, Nowak, S, Oberkofler, M, Ochoukov, R, Ollus, P, Olsen, J, Omotani, J, Ongena, J, Orain, F, Orsitto, F, Paccagnella, R, Palha, A, Panaccione, L, Panek, R, Panjan, M, Papp, G, Paradela Perez, I, Parra, F, Passeri, M, Pau, A, Pautasso, G, Pavlichenko, R, Perek, A, Pericoli Radolfini, V, Pesamosca, F, Peterka, M, Petrzilka, V, Piergotti, V, Pigatto, L, Piovesan, P, Piron, C, Piron, L, Plyusnin, V, Pokol, G, Poli, E, Poloskei, P, Popov, T, Popovic, Z, Por, G, Porte, L, Pucella, G, Puiatti, M, Putterich, T, Rabinski, M, Juul Rasmussen, J, Rasmussen, J, Ratta, G, Ratynskaia, S, Ravensbergen, T, Refy, D, Reich, M, Reimerdes, H, Reimold, F, Reiser, D, Reux, C, Reznik, S, Ricci, D, Rispoli, N, Rivero-Rodriguez, J, Rocchi, G, Rodriguez-Ramos, M, Romano, A, Rosato, J, Rubinacci, G, Rubino, G, Ryan, D, Salewski, M, Salmi, A, Samaddar, D, Sanchis-Sanchez, L, Santos, J, Sarkimaki, K, Sassano, M, Sauter, O, Scannell, R, Scheffer, M, Schneider, B, Schneider, P, Schrittwieser, R, Schubert, M, Seidl, J, Seliunin, E, Sharapov, S, Sheeba, R, Sias, G, Sieglin, B, Silva, C, Sipila, S, Smith, S, Snicker, A, Solano, E, Hansen, S, Soria-Hoyo, C, Sorokovoy, E, Sozzi, C, Sperduti, A, Spizzo, G, Spolaore, M, Stejner, M, Stipani, L, Stober, J, Strand, P, Sun, H, Suttrop, W, Sytnykov, D, Szepesi, T, Tal, B, Tala, T, Tardini, G, Tardocchi, M, Teplukhina, A, Terranova, D, Testa, D, Theiler, C, Thoren, E, Thornton, A, Tilia, B, Tolias, P, Tomes, M, Toscano-Jimenez, M, Tsironis, C, Tsui, C, Tudisco, O, Urban, J, Valisa, M, Vallar, M, Vallejos Olivares, P, Valovic, M, Van Vugt, D, Vanovac, B, Varje, J, Varju, J, Varoutis, S, Vartanian, S, Vasilovici, O, Vega, J, Verdoolaege, G, Verhaegh, K, Vermare, L, Vianello, N, Vicente, J, Viezzer, E, Villone, F, Voitsekhovitch, I, Voltolina, D, Vondracek, P, Vu, N, Walkden, N, Wauters, T, Weiland, M, Weinzettl, V, Wensing, M, Wiesen, S, Wiesenberger, M, Wilkie, G, Willensdorfer, M, Wischmeier, M, Wu, K, Xiang, L, Zagorski, R, Zaloga, D, Zanca, P, Zaplotnik, R, Zebrowski, J, Zhang, W, Zisis, A, Zoletnik, S, Zuin, M, Universitat Politècnica de Catalunya. Departament de Física, Universitat Politècnica de Catalunya. ANT - Advanced Nuclear Technologies Research Group, Control Systems Technology, Science and Technology of Nuclear Fusion, Data Mining, Sensorics for fusion reactors, and Magneto-Hydro-Dynamic Stability of Fusion Plasmas

Subjects
Nuclear and High Energy Physics, Settore ING-INF/04, Work package, grassy ELM, ballooning modes, Nuclear physics, 01 natural sciences, Flattening, Ballooning, 010305 fluids & plasmas, grassy ELMs, separatrix density, ASDEX Upgrade, [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], 0103 physical sciences, 010306 general physics, Edge-localized mode, QC, H-mode, plasma triangularity, type-II ELMs, Physics, Física [Àrees temàtiques de la UPC], type-II ELM, Plasma, Condensed Matter Physics, Null (physics), Shear (sheet metal), Física nuclear, Atomic physics, ballooning mode
Abstract

Within the EUROfusion MST1 work package, a series of experiments has been conducted on AUG and TCV devices to disentangle the role of plasma fueling and plasma shape for the onset of small ELM regimes. On both devices, small ELM regimes with high confinement are achieved if and only if two conditions are fulfilled at the same time. Firstly, the plasma density at the separatrix must be large enough (), leading to a pressure profile flattening at the separatrix, which stabilizes type-I ELMs. Secondly, the magnetic configuration has to be close to a double null (DN), leading to a reduction of the magnetic shear in the extreme vicinity of the separatrix. As a consequence, its stabilizing effect on ballooning modes is weakened. Peer Reviewed Article escrit per 365 autors/autores: Labit, B.; Eich, T.; Harrer, G. F.; Wolfrum, E.; Bernert, M.; Dunne, M. G.; Frassinetti, L.; Hennequin, P.; Maurizio, R.; Merle, A.; Meyer, H.; Saarelma, S.; Sheikh, U.; Adamek, J.; Agostini, M.; Aguiam, D.; Akers, R.; Albanese, R.; Albert, C.; Alessi, E.; Ambrosino, R.; Andr be, Y.; Angioni, C.; Apruzzese, G.; Aradi, M.; Arnichand, H.; Auriemma, F.; Avdeeva, G.; Ayllon-Guerola, J. M.; Bagnato, F.; Bandaru, V. K.; Barnes, M.; Barrera-Orte, L.; Bettini, P.; Bilato, R.; Biletskyi, O.; Bilkova, P.; Bin, W.; Blanchard, P.; Blanken, T.; Bobkov, V.; Bock, A.; Boeyaert, D.; Bogar, K.; Bogar, O.; Bohm, P.; Bolzonella, T.; Bombarda, F.; Boncagni, L.; Bouquey, F.; Bowman, C.; Brezinsek, S.; Brida, D.; Brunetti, D.; Bucalossi, J.; Buchanan, J.; Buermans, J.; Bufferand, H.; Buller, S.; Buratti, P.; Burckhart, A.; Calabr, G.; Calacci, L.; Camenen, Y.; Cannas, B.; Cano Megías, P.; Carnevale, D.; Carpanese, F.; Carr, M.; Carralero, D.; Carraro, L.; Casolari, A.; Cathey, A.; Causa, F.; Cavedon, M.; Cecconello, M.; Ceccuzzi, S.; Cerovsky, J.; Chapman, S.; Chmielewski, P.; Choi, D.; Cianfarani, C.; Ciraolo, G.; Coda, S.; Coelho, R.; Colas, L.; Colette, D.; Cordaro, L.; Cordella, F.; Costea, S.; Coster, D.; Cruz Zabala, D. J.; Cseh, G.; Czarnecka, A.; Cziegler, I.; D’Arcangelo, O.; Dal Molin, A.; David, P.; De Carolis, G.; De Oliveira, H.; Decker, J.; Dejarnac, R.; Delogu, R.; Den Harder, N.; Dimitrova, M.; Dolizy, F.; Domínguez-Palacios Durán, J. J.; Douai, D.; Drenik, A.; Dreval, M.; Dudson, B.; Dunai, D.; Duval, B. P.; Dux, R.; Elmore, S.; Embréus, O.; Erds, B.; Fable, E.; Faitsch, M.; Fanni, A.; Farnik, M.; Faust, I.; Faustin, J.; Fedorczak, N.; Felici, F.; Feng, S.; Feng, X.; Ferreira, J.; Ferr, G.; Février, O.; Ficker, O.; Figini, L.; Figueiredo, A.; Fil, A.; Fontana, M.; Francesco, M.; Fuchs, C.; Futatani, S.; Gabellieri, L.; Gadariya, D.; Gahle, D.; Galassi, D.; Gałązka, K.; Galdon-Quiroga, J.; Galeani, S.; Gallart, D.; Gallo, A.; Galperti, C.; Garavaglia, S.; Garcia, J.; Garcia-Lopez, J.; Garcia-Mu oz, M.; Garzotti, L.; Gath, J.; Geiger, B.; Giacomelli, L.; Giannone, L.; Gibson, S.; Gil, L.; Giovannozzi, E.; Giruzzi, G.; Gobbin, M.; Gonzalez-Martin, J.; Goodman, T. P.; Gorini, G.; Gospodarczyk, M.; Granucci, G.; Grekov, D. 1; Grenfell, G.; Griener, M.; Groth, M.; Grover, O.; Gruca, M.; Gude, A.; Guimarais, L.; Gyergyek, T.; Hacek, P.; Hakola, A.; Ham, C.; Happel, T.; Harrison, J.; Havranek, A.; Hawke, J.; Henderson, S.; Hesslow, L.; Hitzler, F.; Hnat, B.; Hobirk, J.; Hoelzl, M.; Hogeweij, D.; Hopf, C.; Hoppe, M.; Horacek, J.; Hron, M.; Huang, Z.; Iantchenko, A.; Iglesias, D.; Igochine, V.; Innocente, P.; Ionita-Schrittwieser, C.; Isliker, H.; Ivanova-Stanik, I.; Jacobsen, A.; Jakubowski, M.; Janky, F.; Jardin, A.; Jaulmes, F.; Jensen, T.; Jonsson, T.; Kallenbach, A.; Kappatou, A.; Karpushov, A.; Kasilov, S.; Kazakov, Y.; Kazantzidis, P. V.; Keeling, D.; Kelemen, M.; Kendl, A.; Kernbichler, W.; Kirk, A.; Kocsis, G.; Komm, M.; Kong, M.; Korovin, V.; Koubiti, M.; Kovacic, J.; Krawczyk, N.; Krieger, K.; Kripner, L.; Křivská, A.; Kudlacek, O.; Kulyk, Y.; Kurki-Suonio, T.; Kwiatkowski, R.; Laggner, F.; Laguardia, L.; Lahtinen, A.; Lang, P.; Likonen, J.; Lipschultz, B.; Liu, F.; Lombroni, R.; Lorenzini, R.; Loschiavo, V. P.; Lunt, T.; MacUsova, E.; Madsen, J.; Maggiora, R.; Maljaars, B.; Manas, P.; Mantica, P.; Mantsinen, M. J.; Manz, P.; Maraschek, M.; Marchenko, V.; Marchetto, C.; Mariani, A.; Marini, C.; Markovic, T.; Marrelli, L.; Martin, P.; Martín Solís, J. R.; Martitsch, A.; Mastrostefano, S.; Matos, F.; Matthews, G.; Mayoral, M.-L.; Mazon, D.; Mazzotta, C.; Mc Carthy, P.; McClements, K.; McDermott, R.; McMillan, B.; Meineri, C.; Menkovski, V.; Meshcheriakov, D.; Messmer, M.; Micheletti, D.; Milanesio, D.; Militello, F.; Miron, I. G.; Mlynar, J.; Moiseenko, V.; Molina Cabrera, P. 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Published
2019

45. Understanding Patient Experiences to Inform Future Studies to Optimize Personalization of Treatment for Early Breast Cancer.

Author

McIntosh SA, Mactier M, Fairhurst K, Gath J, Stobart H, and Potter S

Subjects
Humans, Female, Middle Aged, Surveys and Questionnaires, Adult, Aged, Prognosis, Follow-Up Studies, Combined Modality Therapy, Survival Rate, Aged, 80 and over, Breast Neoplasms therapy, Breast Neoplasms pathology, Quality of Life, Precision Medicine
Abstract

Background: Breast cancer treatment is multimodal, but not all patients benefit from each treatment, and many experience morbidities significantly impacting quality of life. There is increasing interest in tailoring breast cancer treatments to optimize oncological outcomes and reduce treatment burden, but it is vital that future trials focus on treatments that most impact patients. This study was designed to explore patient experiences of treatment to inform future research., Methods: An online survey was co-developed with patient advocates to explore respondents' experiences of breast cancer treatment. Questions included simple demographics, treatments received, and views regarding omitting treatments if that is deemed safe. The survey was circulated via social media and patient advocacy groups. Responses were summarized by using simple statistics; free text was analyzed thematically., Results: Of the 235 participants completing the survey, 194 (82.6%) would choose to omit a specific treatment if safe to do so. The most commonly selected treatments were chemotherapy (n = 69, 35.6%) and endocrine therapy (n = 61, 31.4%) mainly due to side effects. Fewer respondents would choose to omit surgery (n = 40, 20.6%) or radiotherapy (n = 20, 10.3%). Several women commented that survival was their "absolute priority" and that high-quality evidence to support the safety of reducing treatment would be essential., Conclusions: Patients with breast cancer are individuals who may wish to optimize different components of their treatment. A portfolio of studies co-designed with patients is needed to establish an evidence base for greater treatment personalization with studies focused on reducing avoidable chemotherapy and endocrine therapy a priority., (© 2024. The Author(s).)

Published
2024
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46. The feasibility and acceptability of an app-based intervention with brief behavioural support (APPROACH) to promote brisk walking in people diagnosed with breast, prostate and colorectal cancer in the UK.

Author

Lally P, Kennedy F, Smith S, Beeken RJ, Buck C, Thomas C, Counsell N, Wyld L, Martin C, Williams S, Roberts A, Greenfield DM, Gath J, Potts HWW, Latimer N, Smith L, and Fisher A

Subjects
Male, Humans, Prostate, Feasibility Studies, Walking, United Kingdom, Mobile Applications, Colorectal Neoplasms therapy
Abstract

Introduction: Increased moderate to vigorous physical activity (MVPA) can improve clinical and psychosocial outcomes for people living with and beyond cancer (LWBC). This study aimed to assess the feasibility and acceptability of trial procedures in a pilot randomised controlled trial (RCT) of a theory-driven app-based intervention with behavioural support focused on promoting brisk walking (a form of MVPA) in people LWBC (APPROACH)., Methods: Participants diagnosed with breast, prostate or colorectal cancer were recruited from a single UK hospital site. Assessments at baseline and 3 months included online questionnaires, device-measured brisk walking (activPAL accelerometer) and self-reported weight and height. Participants were randomised to intervention or control (care as usual). The intervention comprised a non-cancer-specific app to promote brisk walking (National Health Service 'Active 10') augmented with print information about habit formation, a walking planner and two behavioural support telephone calls. Feasibility and acceptability of trial procedures were explored. Initial estimates for physical activity informed a power calculation for a phase III RCT. A preliminary health economics analysis was conducted., Results: Of those medically eligible, 369/577 (64%) were willing to answer further eligibility questions and 90/148 (61%) of those eligible were enrolled. Feasibility outcomes, including retention (97%), assessment completion rates (>86%) and app download rates in the intervention group (96%), suggest that the trial procedures are acceptable and that the intervention is feasible. The phase III RCT will require 472 participants to be randomised. As expected, the preliminary health economic analyses indicate a high level of uncertainty around the cost-effectiveness of the intervention., Conclusions: This pilot study demonstrates that a large trial of the brisk walking intervention with behavioural support is both feasible and acceptable to people LWBC. The results support progression onto a confirmatory phase III trial to determine the efficacy and cost-effectiveness of the intervention., (© 2024 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.)

Published
2024
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47. British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy.

Author

Sidhu R, Turnbull D, Haboubi H, Leeds JS, Healey C, Hebbar S, Collins P, Jones W, Peerally MF, Brogden S, Neilson LJ, Nayar M, Gath J, Foulkes G, Trudgill NJ, and Penman I

Subjects
Humans, Conscious Sedation, Endoscopy, Gastrointestinal adverse effects, Endoscopy, Gastrointestinal methods, Benzodiazepines, Gastroenterology, Propofol
Abstract

Over 2.5 million gastrointestinal endoscopic procedures are carried out in the United Kingdom (UK) every year. Procedures are carried out with local anaesthetic r with sedation. Sedation is commonly used for gastrointestinal endoscopy, but the type and amount of sedation administered is influenced by the complexity and nature of the procedure and patient factors. The elective and emergency nature of endoscopy procedures and local resources also have a significant impact on the delivery of sedation. In the UK, the vast majority of sedated procedures are carried out using benzodiazepines, with or without opiates, whereas deeper sedation using propofol or general anaesthetic requires the involvement of an anaesthetic team. Patients undergoing gastrointestinal endoscopy need to have good understanding of the options for sedation, including the option for no sedation and alternatives, balancing the intended aims of the procedure and reducing the risk of complications. These guidelines were commissioned by the British Society of Gastroenterology (BSG) Endoscopy Committee with input from major stakeholders, to provide a detailed update, incorporating recent advances in sedation for gastrointestinal endoscopy.This guideline covers aspects from pre-assessment of the elective 'well' patient to patients with significant comorbidity requiring emergency procedures. Types of sedation are discussed, procedure and room requirements and the recovery period, providing guidance to enhance safety and minimise complications. These guidelines are intended to inform practising clinicians and all staff involved in the delivery of gastrointestinal endoscopy with an expectation that this guideline will be revised in 5-years' time., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2024
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48. Outcomes of complex oncoplastic breast surgery in older women. Analysis of data from the Age Gap cohort study.

Author

Quddus R, Banks J, Morgan JL, Martin C, Reed MW, Walters S, Cheung KL, Todd A, Audisio R, Green T, Revell D, Gath J, Horgan K, Holcombe C, Parmeshwar R, Thompson A, and Wyld L

Subjects
Female, Humans, Aged, Mastectomy, Cohort Studies, Quality of Life, Mastectomy, Segmental, Breast Neoplasms surgery, Mammaplasty
Abstract

Key Words: Breast cancer, mastectomy, breast conserving surgery, post-mastectomy reconstruction, older women, quality of life., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 Published by Elsevier Ltd.)

Published
2023
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49. The value of standards for health datasets in artificial intelligence-based applications.

Author

Arora A, Alderman JE, Palmer J, Ganapathi S, Laws E, McCradden MD, Oakden-Rayner L, Pfohl SR, Ghassemi M, McKay F, Treanor D, Rostamzadeh N, Mateen B, Gath J, Adebajo AO, Kuku S, Matin R, Heller K, Sapey E, Sebire NJ, Cole-Lewis H, Calvert M, Denniston A, and Liu X

Subjects
Humans, Consensus, Systematic Reviews as Topic, Artificial Intelligence, Delivery of Health Care
Abstract

Artificial intelligence as a medical device is increasingly being applied to healthcare for diagnosis, risk stratification and resource allocation. However, a growing body of evidence has highlighted the risk of algorithmic bias, which may perpetuate existing health inequity. This problem arises in part because of systemic inequalities in dataset curation, unequal opportunity to participate in research and inequalities of access. This study aims to explore existing standards, frameworks and best practices for ensuring adequate data diversity in health datasets. Exploring the body of existing literature and expert views is an important step towards the development of consensus-based guidelines. The study comprises two parts: a systematic review of existing standards, frameworks and best practices for healthcare datasets; and a survey and thematic analysis of stakeholder views of bias, health equity and best practices for artificial intelligence as a medical device. We found that the need for dataset diversity was well described in literature, and experts generally favored the development of a robust set of guidelines, but there were mixed views about how these could be implemented practically. The outputs of this study will be used to inform the development of standards for transparency of data diversity in health datasets (the STANDING Together initiative)., (© 2023. The Author(s).)

Published
2023
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50. Study within a trial of electronic versus paper-based Patient-Reported oUtcomes CollEction (SPRUCE): study protocol for a partially randomised patient preference study.

Author

Philipps L, Foster S, Gardiner D, Gath J, Gillman A, Haviland J, Hill E, King D, Manning G, Stiles M, Hall E, and Lewis R

Subjects
Humans, Data Collection, Electronics, Patient Reported Outcome Measures, Patient Preference, Academies and Institutes
Abstract

Introduction: Patient-reported outcomes (PRO) are currently collected from trial participants using paper questionnaires by the Clinical Trials and Statistics Unit at The Institute of Cancer Research (ICR-CTSU). Streamlining PRO collection using electronic questionnaires (ePRO) may improve data collection and patient experience. Here, we outline our protocol for a Study within a trial of electronic versus paper-based Patient-Reported oUtcomes CollEction (SPRUCE), which investigates the acceptability of ePRO in oncology clinical trials., Methods and Analysis: SPRUCE was developed alongside patient and public contributors. SPRUCE runs in multiple host trials with a partially randomised patient preference design, allowing participants to be randomised or choose their preference of electronic or paper questionnaires. Questionnaires are scheduled in accordance with host trial follow-up. The primary objective will assess differences in return rates (compliance) between ePRO and paper PROs at the first timepoint post-host trial intervention in the randomised group. Paper PRO compliance is expected to be 90%. 244 randomised participants are required to exclude ≤80% compliance rates with ePRO (10% non-inferiority margin, with 80% power and one-sided alpha=0.05). SPRUCE aims to assess acceptability of ePRO in oncology clinical trials, establish whether ePRO is acceptable to ICR-CTSU trial participants and can capture complete PRO data, consistent with paper PROs., Ethics and Dissemination: The SPRUCE protocol (ICR-CTSU/2021/10074) was approved by the Coventry and Warwick Central Research Ethics Committee (21/WM/0223) on 21 October 2021. Results will be disseminated via presentations, publications and lay summaries. No participant identifiable data will be included., Trial Registration: SWAT169., Competing Interests: Competing interests: EH receives support from a Cancer Research UK (CRUK) core grant (C1491/A25351) and LP receives support from her PhD by a CRUK clinical trials fellowship (A30384); no other authors have any potential conflicts of interests to declare., (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2023
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