237 results on '"Gascou, Gregory"'
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2. Outcomes Following Mechanical Thrombectomy in Different Etiological Subtypes of Acute Basilar Artery Occlusion: Stroke Etiology and Outcome after EVT in BAO
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Abdelrady, Mohamed, Derraz, Imad, Dargazanli, Cyril, Cagnazzo, Federico, Ognard, Julien, Riquelme, Carlos, Cheddad El Aouni, Mourad, Lefevre, Pierre-Henri, Ben Salem, Douraied, Gascou, Gregory, Gentric, Jean-Christophe, Arquizan, Caroline, Costalat, Vincent, and Mourand, Isabelle more...
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- 2023
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3. Current and future trends in acute ischemic stroke treatment: direct-to-angiography suite, middle vessel occlusion, large core, and minor strokes
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Radu, Răzvan Alexandru, Gascou, Gregory, Machi, Paolo, Capirossi, Carolina, Costalat, Vincent, and Cagnazzo, Federico
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- 2023
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4. Negative susceptibility vessel sign might be predictive of complete reperfusion in patients with acute basilar artery occlusion managed with thrombectomy
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Abdelrady, Mohamed, Derraz, Imad, Lefevre, Pierre-Henri, Cagnazzo, Federico, Gascou, Gregory, Arquizan, Caroline, Gentric, Jean-Christophe, Mourand, Isabelle, Dargazanli, Cyril, Ognard, Julien, and Costalat, Vincent more...
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- 2023
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5. Successful Thrombectomy Improves Functional Outcome in Tandem Occlusions with a Large Ischemic Core
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Lapergue, Bertrand, Wang, Adrien, Consoli, Arturo, Coskun, Oguzhan, Maria, Federico Di, Pizzuto, Silvia, Sgreccia, Alessandro, Benoit, Charline, Gorza, Lucas, Weisenburger-Lile, David, Jabeur, Waliyde, Maia, Tchikviladze, Evrard, Serge, Rodesch, Georges, Blanc, Raphaël, Obadia, Michael, Desilles, Jean-Philippe, Piotin, Michel, Seners, Pierre, Smajda, Stanislas, Escalard, Simon, Maier, Benjamin, Sabben, Candice, Redjem, Hocine, Mikaelmazhigi, Adwan, Grace, Delvoye, François, Raaisi, Amira Al, Boisseau, William, Eker, Omer, Cho, Tae-Hee, Derex, Laurent, Fontaine, Julia, Mechtouff, Laura, Nighoghossian, Norbert, Ong, Elodie, Rascle, Lucie, Riva, Roberto, Turjman, Françis, Laubacher, Morgane, Beyragued, Mehdi, Berthezene, Yves, Hermier, Marc, Roxanna, Ameli, Bani-Sadr, Alexandre, Filip, Andrea, Cappucci, Matteo, Bourcier, Romain, Duport, Benjamin Daumas, Alexandre, Pierre Louis, Lenoble, Cédric, Hubertdesal, Gaalon, Solène De, Guillon, Benoît, Preterre, Cécile, Tessier, Guillaume, Lionnet, Arthur, Gory, Benjamin, Humbertjean-Selton, Lisa, Anxionnat, René, Derelle, Anne-Laure, Liao, Liang, Schmitt, Emmanuelle, Planel, Sophie, Richard, Sébastien, Mione, Gioia, Lacour, Jean-Christophe, Douarinou, Marian, Micard, Emilien, Chen, Bailiang, Audibert, Gérard, Masson, Agnès, Alb, Lionel, Beaumont, Marine, Tabarna, Adriana, Voicu, Marcela, Barthel, Grégoire, Podar, Iona, Brezeanu, Madalina, Reitter, Marie, Zhu, François, Marnat, Gaultier, Liegey, Jean-Sébastien, Briau, Pierre, Papillon, Lisa, Sibon, Igor, Barreau, Xavier, Papaxanthos, Jean, Berge, Jérome, Debruxelles, Sabrina, Olindo, Stephane, Poli, Mathilde, Renou, Pauline, Sagnier, Sharmila, Tourdias, Thomas, Courret, Thomas, Lucas, Ludovic, Milnerowicz, Malgorzata, Dargazanli, Cyril, Costalat, Vincent, Mourand, Isabelle, Arquizan, Caroline, Corti, Lucas, Adrien, Schiphorst, Ter, Federico, Cagnazzo, Derraz, Imad, Mahmoudi, Mehdi, Lefevre, Pierre-Henri, Gascou, Grégory, Spelle, Laurent, Caroff, Jildaz, Denier, Christian, Chalumeau, Vanessa, Mihalea, Cristian, Nicolaslegris, Ozanne, Augustin, Ikka, Leon, Chassin, Olivier, Gallas, Sophie, Venditti, Laura, Marianasarov, Cortese, Jonathan, Ferre, Jean-Christophe, Vannier, Stephane, Ronziere, Thomas, Veronica Lassalle, Maria, Gauvrit, Jean-Yves, Tracol, Clément, Boustia, Abdelghani Fakhreddine, Malrain, Cécile, Beaufreton, Edouard, Lapotre, Thibault, Alias, Quentin, Hissier, Julien, Guillen, Maud, Eugene, François, Chivot, Cyril, Courselle, Audrey, Ouin, Elisa, Lamy, Chantal, Delaforge, Kevin, Fernandez, Manuel, Vial, Jérémie, Laferte, Quentin, Desdoit, Xavier, Timsit, Serge, Jourdain, Aurore, Gentric, Jean-Christophe, Ognard, Julien, Viakhireva, Irina, Coris, Jordan, Prud'hon, Sabine, Merrien, François-Mathias, Marechal, Denis, Bruguet, Marie, Rousseau, Pierre Yves, Goas, Philippe, Boulanger, Marion, Touze, Emmanuel, Vivien, Denis, Barbier, Charlotte, Schneckenburger, Romain, Salaris, Fabrizio, Cogez, Julien, Guettier, Sophie, Porte, Estelle La, Bouchart, Jean, Mounayer, Charbel, Rouchaud, Aymeric, Saleme, Suzana, Forestier, Géraud, Clarencon, Frédéric, Rosso, Charlotte, Leder, Sara, Baronnet, Flore, Crozier, Sophie, Leger, Anne, Premat, Kevin, Eimad, Shotar, Lenck, Stéphanie, Sourour, Nader, Bottin, Laure, Ghazanfari, Sam, Yger, Marion, Alamowitch, Sonia, Delorme, Stephen, Wittwer, Aymeric, Vassilev, Christine, Naggara, Olivier, Turc, Guillaume, Hassen, Wagih Ben, Kerleroux, Basile, Trystram, Denis, Rodriguez-Regent, Christine, Ozkul-Wermester, Ozlem, Papagiannaki, Chrysanthi, Massardier, Evelyne, Triquenot, Aude, Lefebvre, Margaux, Burel, Julien, Viguier, Alain, Cognard, Christophe, Januel, Anne Christine, Albucher, Jean-François, Calviere, Lionel, Olivot, Jean-Marc, Darcourt, Jean, Raposo, Nicolas, Bonneville, Fabrice, Bellanger, Guillaume, Fontaine, Louis, Tall, Philippe, Thalamas, Claire, Geerearts, Thomas, Grepon, Antoine Faurie, Bourdain, Frédéric, Bernady, Patricia, Ballan, Guillaume, Bannier, Stéphanie, Ellie, Emmanuel, Flabeau, Olivier, Potenza, Julia, Soulages, Antoine, Lagoarde-Segot, Laurent, Cailliez, Hélène, Veunac, Louis, Higue, David, Lebras, Anthony, Adam, Sarah, Pegat, Benoit, Guen, Arnaud Le, Chedeville, François, Jouan, Jérémy, Demasles, Stéphanie, Richter, Johann Sebastian, Thierry Barroso, Bruno, Dahan, Camille, Gonnet, Alexis, Hubrecht, Régis, Lepine, Zoé, Castagnet, Hélène, Marasescu, Raluca, Heck, Olivier, Cuisenier, Pauline, Detante, Olivier, Wiki, Isabelle Favre, Bonaz, Clémentine, Garambois, Katia, Legris, Loic, Kastler, Adrian, Boubagra, Kamel, Berthet, Corentin, Charara, Stéphane, Wolff, Valérie, Pop, Raoul, Quenardelle, Véronique, Lauer, Valérie, Pierre-Paul, Irène, Roxanagheoca, Trzeciak, Malwina, Moulin, Solène, Tuan, Hua Vi, Pagano, Paolo, Doucet, Alexandre, Gelmini, Christophe, Manceau, Pierrefrançois, Paiusan, Laurentiu, Serre, Isabelle, Soize, Sébastien, Phuong Nguyen, Thi Ngoc, Sahnoun, Maher, Caucheteux, Nathalie, Ferrier, Anna, Zerroug, Abderrahim, Moreno, Ricardo, Chabert, Emmanuel, Lteif, Elie, Paulineparis, Bourgois, Nathalie, Raquin, Marie, Pasco-Papon, Anne, Girot, Jean Baptiste, Lecluse, Alderic, Godard, Sophie, L'allinec, Vincent, Janot, Kevin, Bibi, Richard, Gaudron, Marie, Bretonniere, Arnaud, Annan, Mariam, Ifergan, Héloïse, Boulouis, Grégoire, Pasi, Marco, Debiais, Séverine, Molinier, Elisabeth, Wietrich, Anthony, Ruche, Valérie, Lavandier, Karine, Bejot, Yannick, Lemogne, Brivale, Ricolfi, Fédéric, Baptiste, Laura, Thouant, Pierre, Duloquin, Gaulthier, Olivier Comby, Pierre, Charbonnier, Guillaume, Bonnet, Louise, Raybaud, Nicolas, Bouamra, Benjamin, Moulin, Thierry, Biondi, Alessandra, Finitsis, Stephanos, and Mazighi, Mikael more...
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- 2023
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6. Ticagrelor versus clopidogrel dual antiplatelet therapy for unruptured intracranial aneurysms treated with flowdiverter
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Papaxanthos, Jean, Cagnazzo, Federico, Collemiche, François-Louis, Barreau, Xavier, Radu, Răzvan Alexandru, Gariel, Florent, Derraz, Imad, Gascou, Gregory, Riquelme, Carlos, Ferreira, Ivan, Lefevre, Pierre-Henri, Berge, Jérôme, Costalat, Vincent, Dargazanli, Cyril, and Marnat, Gaultier more...
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- 2023
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7. Complete recanalization predicts favorable outcome in patients with distal M2-M3 middle cerebral artery occlusions following endovascular thrombectomy
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ABDELRADY, Mohamed, DERRAZ, Imad, DARGAZANLI, Cyril, CHEDDAD EL AOUNI, Mourad, LEFEVRE, Pierre-Henri, CAGNAZZO, Federico, RIQUELME, Carlos, GASCOU, Gregory, ARQUIZAN, Caroline, MOURAND, Isabelle, BEN SALEM, Douraied, COSTALAT, Vincent, GENTRIC, Jean-Christophe, and OGNARD, Julien more...
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- 2023
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8. Successful thrombectomy is beneficial in patients with pre-stroke disability: Results from an international multicenter cohort study
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Piotin, Michel, Blanc, Raphael, Escalard, Hocine Redjem Simon, Desilles, Jean-Philippe, Delvoye, François, Smajda, Stanislas, Maier, Benjamin, Hebert, Solène, Mazighi, Mikael, Obadia, Mikael, Sabben, Candice, Seners, Pierre, Raynouard, Igor, Corabianu, Ovide, de Broucker, Thomas, Manchon, Eric, Taylor, Guillaume, Ben Maacha, Malek, Thion, Laurie-Anne, Lecler, Augustin, Savatovsky, Julien, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Ajili, Nadia, Lapergue, Bertrand, Weisenburger-Lile, David, Gorza, Lucas, Buard, Géraldine, Coskun, Oguzhan, Consoli, Arturo, Di Maria, Federico, Rodesh, Georges, Zimatore, Sergio, Leguen, Morgan, Gratieux, Julie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Marinier, Sylvie, Nighoghossian, Norbert, Riva, Roberto, Eker, Omer, Turjman, Francis, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Lukaszewicz, Anne Claire, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne-Evelyne, Marnat, Gaultier, Gariel, Florent, Barreau, Xavier, Berge, Jérôme, Menegon, Patrice, Sibon, Igor, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Rouanet, François, Tourdias, Thomas, Liegey, Jean-Sebastien, Briau, Pierre, Pangon, Nicolas, Bourcier, Romain, Detraz, Lili, Daumas-Duport, Benjamin, Alexandre, Pierre-Louis, Roy, Monica, Lenoble, Cédric, Desal, Hubert, Guillon, Benoît, de Gaalon, Solène, Preterre, Cécile, Gory, Benjamin, Bracard, Serge, Anxionnat, René, Braun, Marc, Derelle, Anne-Laure, Tonnelet, Romain, Liao, Liang, Zhu, François, Schmitt, Emmanuelle, Planel, Sophie, Richard, Sébastien, Humbertjean, Lisa, Mione, Gioia, Lacour, Jean-Christophe, Riou-Comte, Nolwenn, Audibert, Gérard, Voicu, Marcela, Alb, Ionel, Reitter, Marie, Brezeanu, Madalina, Masson, Agnès, Tabarna, Adriana, Podar, Iona, Macian-montoro, Francisco, Saleme, Suzanna, Mounayer, Charbel, Rouchaud, Aymeric, Costalat, Vincent, Arquizan, Caroline, Dargazanli, Cyril, Gascou, Grégory, Lefèvre, Pierre-Henri, Derraz, Imad, Riquelme, Carlos, Gaillard, Nicolas, Mourand, Isabelle, Corti, Lucas, Cagnazzo, Federico, ter Schiphorst, Adrien, Francois, Eugene, Vannier, Stéphane, Ferre, Jean-christophe, Raoult, Helene, Ronziere, Thomas, Lassale, Maria, Paya, Christophe, Gauvrit, Jean-Yves, Tracol, Clément, Langnier-Lemercier, Sophie, Samson, Yves, Rosso, Charlotte, Leger, Anne, Deltour, Sandrine, Clarencon, Frederic, Shotar, Eimad, Spelle, Laurent, Denier, Christian, Chassin, Olivier, Chalumeau, Vanessa, Caroff, Jildaz, Venditti, Laura, Naggara, Olivier, Hassen, Wagih Ben, Boulouis, Grégoire, Rodriguez-Régent, Christine, Trystram, Denis, Kerleroux, Basile, Turc, Guillaume, Domigo, Valérie, Lamy, Catherine, Birchenall, Julia, Isabel, Clothilde, Lun, François, Viguier, Alain, Cognard, Christophe, Januel, Anne Christine, Olivot, Jean-Marc, Raposo, Nicolas, Bonneville, Fabrice, Albucher, Jean François, Calviere, Lionel, Darcourt, Jean, Tall, Philippe, Bellanger, Guillaume, Fontaine, Louis, Touze, Emmanuel, Barbier, Charlotte, Schneckenburger, Romain, Boulanger, Marion, Cogez, Julien, Guettier, Sophie, Timsit, Serge, Gentric, Jean-christophe, Ognard, Julien, Merrien, Francois Mathias, Wermester, Ozlem Ozkul, Massardier, Evelyne, Papagiannaki, Chrysanthi, Bourdain, Frédéric, Bernady, Patricia, Lagoarde-Segot, Laurent, Cailliez, Hélène, Veunac, Louis, Higue, David, Wolff, Valérie, Pop, Raoul, Beaujeux, Rémi, Dan-Sorin, Mihoc, Manisor, Monica, Le Bras, Anthony, Evain, Sarah, Le Guen, Arnaud, Richter, Sebastian, Hubrecht, Regis, Demasles, Stéphanie, Barroso, Bruno, Sablot, Denis, Farouil, Geoffroy, Tardieu, Maxime, Smadja, Philippe, Aptel, Sabine, Seiler, Ian, Ducroux, Célina, Nourredine, Mikaïl, Haesebaert, Julie, Buisson, Marielle, Alesefir, Walid, Boisseau, William, Daneault, Nicole, Deschaintre, Yan, Diestro, Jose Danilo B., Eneling, Johanna, Gioia, Laura C., Iancu, Daniella, Jacquin, Grégory, Odier, Céline, Stapf, Christian, Raymond, Jean, Roy, Daniel, Weill, Alain, and Poppe, Alexandre Y. more...
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- 2023
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9. FLAIR vascular hyperintensities predict functional outcome after endovascular thrombectomy in patients with large ischemic cores
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Derraz, Imad, Ahmed, Raed, Mourand, Isabelle, Dargazanli, Cyril, Cagnazzo, Federico, Gaillard, Nicolas, Gascou, Gregory, Riquelme, Carlos, Lefevre, Pierre-Henri, Bonafe, Alain, Arquizan, Caroline, and Costalat, Vincent more...
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- 2022
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10. Benefit of mechanical thrombectomy in acute ischemic stroke related to calcified cerebral embolus
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Grand, Téodor, Dargazanli, Cyril, Papagiannaki, Chrysanthi, Bruggeman, Agnetha, Maurer, Christoph, Gascou, Gregory, Fauche, Cédric, Bourcier, Romain, Tessier, Guillaume, Blanc, Raphaël, Machaa, Malek Ben, Marnat, Gaultier, Barreau, Xavier, Ognard, Julien, Gentric, Jean-Christophe, Barbier, Charlotte, Gory, Benjamin, Rodriguez, Christine, Boulouis, Grégoire, Eugène, François, Thouant, Pierre, Ricolfi, Frederic, Janot, Kevin, Herbreteau, Denis, Eker, Omer Faruk, Cappucci, Matteo, Dobrocky, Tomas, Möhlenbruch, Markus, Demerath, Theo, Psychogios, Marios, Fischer, Sebastian, Cianfoni, Alessandro, Majoie, Charles, Emmer, Bart, Marquering, Henk, Valter, Rémi, Lenck, Stéphanie, Premat, Kévin, Cortese, Jonathan, Dormont, Didier, Sourour, Nader-Antoine, Shotar, Eimad, Samson, Yves, and Clarençon, Frédéric more...
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- 2022
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11. Becoming a thrombectomy-capable stroke center: Clinical and medico-economical effectiveness at the hospital level.
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Checkouri, Thomas, Sablot, Denis, Varnier, Quentin, Fryder, Ivan, Collemiche, Francois-Louis, Azais, Benoit, Dargazanli, Cyril, Leibinger, Franck, Cagnazzo, Federico, Mahmoudi, Mehdi, Lefevre, Pierre-Henri, Van Damme, Laurene, Gascou, Gregory, Schmidt, Julia, Arquizan, Caroline, Plantard, Carole, Farouil, Geoffroy, and Costalat, Vincent more...
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- 2024
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12. Safety and efficacy of the Silk flow diverter: Insight from the DIVERSION prospective cohort study
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Costalat, Vincent, Gascou, Gregory, Dargazanli, Cyril, Soize, Sébastien, Metaxas, Georges, Moret, Jacques, Ikka, Léon, Caroff, Jildaz, Rouchaud, Aymeric, Mihaela, Christian, Benachour, Nidal, Piotin, Michel, Blanc, Raphaël, Redjem, Hocine, Pomero, Elisa, Biondi, Alessandra, Cognard, Christophe, Januel, Anne-Christine, Darcourt, Jean, Guenego, Adrien, Tall, Philippe, Bonneville, Fabrice, Mounayer, Charbel, Saleme, Suzana, Sourour, Nader, Clarençon, Frédéric, Barbier, Charlotte, Herbreteau, Denis, Narata, Ana-Paula, Bibi, Richard, Bracard, Serge, Anxionnat, René, Derelle, Anne-Laure, Tonnelet, Romain, Liao, Liang, Chabert, Emmanuel, Brunel, Hervé, Ricolfi, Frederic, Desal, Hubert, Kulcsar, Zsolt, Taschner, Christian, Gariel, Florent, Marnat, Gaultier, Barreau, Xavier, Menegon, Patrice, Bourcier, Romain, Pierot, Laurent, Spelle, Lauren, Bonafé, Alain, Turjman, Francis, Gory, Benjamin, and Berge, Jérôme more...
- Published
- 2021
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13. Thrombectomy for Basilar Artery Occlusion with Mild Symptoms
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Piotin, Michel, Blanc, Raphael, Redjem, Hocine, Escalard, Simon, Desilles, Jean-Philippe, Ciccio, Gabriele, Smajda, Stanislas, Maier, Benjamin, Hebert, Solene, Delvoye, François, Mazighi, Mikael, Obadia, Mikael, Sabben, Candice, Peres, Roxanne, Corabianu, Ovide, de Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Eric, Garcia, Pierre-Yves, Taylor, Guillaume, Ben Maacha, Malek, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Ajili, Nadia, Lapergue, Bertrand, Weisenburger, David, Gorza, Lucas, Buard, Géraldine, Coskun, Oguzhan, Consoli, Arturo, Di Maria, Federico, Rodesh, Georges, Zimatore, Sergio, Leguen, Morgan, Gratieux, Julie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Marinier, Sylvie, Marnat, Gaultier, Gariel, Florent, Barreau, Xavier, Berge, Jérôme, Veunac, Louis, Menegon, Patrice, Sibon, Igor, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Bourcier, Romain, Detraz, Lili, Daumas-Duport, Benjamin, Alexandre, Pierre-Louis, Roy, Monica, Lenoble, Cédric, L'allinec, Vincent, Girot, Jean-Baptiste, Desal, Hubert, Gory, Benjamin, Bracard, Serge, Anxionnat, René, Braun, Marc, Derelle, Anne-Laure, Tonnelet, Romain, Liao, Liang, Zhu, François, Schmitt, Emmanuelle, Planel, Sophie, Richard, Sébastien, Humbertjean, Lisa, Mione, Gioia, Lacour, Jean-Christophe, Bonnerot, Mathieu, Riou-Comte, Nolwenn, Costalat, Vincent, Arquizan, Caroline, Dargazanli, Cyril, Gascou, Grégory, Lefèvre, Pierre-Henri, Derraz, Imad, Riquelme, Carlos, Gaillard, Nicolas, Mourand, Isabelle, Corti, Lucas, François, Eugene, Vannier, Stéphane, Ferre, Jean-Christophe, Raoult, Helene, Ronziere, Thomas, Lassale, Maria, Paya, Christophe, Gauvrit, Jean-Yves, Tracol, Clément, Langnier-Lemercier, Sophie, Guenego, Adrien, Weisenburger-Lile, David, Ducroux, Célina, Labreuche, Julien, Aubertin, Mathilde, Benali, Amel, Guillen, Maud, Eugene, François, Walker, Gregory, Lun, Ronda, and Fahed, Robert more...
- Published
- 2021
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14. Anterior cranial fossa dural arteriovenous fistula: Transarterial embolization from the ophthalmic artery as first-line treatment
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Piergallini, Lorenzo, Tardieu, Maxime, Cagnazzo, Federico, Gascou, Grégory, Dargazanli, Cyril, Derraz, Imad, Costalat, Vincent, Bonafé, Alain, and Lefevre, Pierre-Henri
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- 2021
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15. Inflammation biomarkers in the intracranial blood are associated with outcome in patients with ischemic stroke
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Dargazanli, Cyril, Blaquière, Marine, Moynier, Marinette, de Bock, Frédéric, Labreuche, Julien, ter Schiphorst, Adrien, Derraz, Imad, Radu, Răzvan Alexandru, Gascou, Gregory, Lefevre, Pierre Henri, Rapido, Francesca, Fendeleur, Julien, Arquizan, Caroline, Bourcier, Romain, Marin, Philippe, Machi, Paolo, Cagnazzo, Federico, Hirtz, Christophe, Costalat, Vincent, and Marchi, Nicola more...
- Abstract
BackgroundPerforming endovascular treatment (EVT) in patients with acute ischemic stroke (AIS) allows a port of entry for intracranial biological sampling.ObjectiveTo test the hypothesis that specific immune players are molecular contributors to disease, outcome biomarkers, and potential targets for modifying AIS . MethodsWe examined 75 subjects presenting with large vessel occlusion of the anterior circulation and undergoing EVT. Intracranial blood samples were obtained by microcatheter aspiration, as positioned for stent deployment. Peripheral blood samples were collected from the femoral artery. Plasma samples were quality controlled by electrophoresis and analyzed using a Mesoscale multiplex for targeted inflammatory and vascular factors.ResultsWe measured 37 protein biomarkers in our sample cohort. Through multivariate analysis, adjusted for age, intravenous thrombolysis, pretreatment National Institutes of Health Stroke Scale and Alberta Stroke Program Early CT scores, we found that post-clot blood levels of interleukin-6 (IL-6) were significantly correlated (adjusted P value <0.05) with disability assessed by the modified Rankin Scale (mRS) score at 90 days, with medium effect size. Chemokine (C-C) ligand 17 CCL17/TARC levels were inversely correlated with the mRS score. Examination of peripheral blood showed that these correlations did not reach statistical significance after correction. Intracranial biomarker IL-6 level was specifically associated with a lower likelihood of favorable outcome, defined as a mRS score of 0–2.ConclusionsOur findings show a signature of blood inflammatory factors at the cerebrovascular occlusion site. The correlations between these acute-stage biomarkers and mRS score outcome support an avenue for add-on and localized immune modulatory strategies in AIS. more...
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- 2025
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16. FLAIR vascular hyperintensities and functional outcome in nonagenarians with anterior circulation large-vessel ischemic stroke treated with endovascular thrombectomy
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Derraz, Imad, Ahmed, Raed, Benali, Amel, Corti, Lucas, Cagnazzo, Federico, Dargazanli, Cyril, Gascou, Gregory, Riquelme, Carlos, Lefevre, Pierre-Henri, Bonafe, Alain, Arquizan, Caroline, and Costalat, Vincent more...
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- 2021
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17. Neurological manifestations of patients infected with the SARS-CoV-2: a systematic review of the literature
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Cagnazzo, Federico, Arquizan, Caroline, Derraz, Imad, Dargazanli, Cyril, Lefevre, Pierre-Henri, Riquelme, Carlos, Gaillard, Nicolas, Mourand, Isabelle, Gascou, Gregory, Bonafe, Alain, and Costalat, Vincent more...
- Published
- 2021
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18. Optimal intracranial pressure in patients with aneurysmal subarachnoid hemorrhage treated with coiling and requiring external ventricular drainage
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Cagnazzo, Federico, Chalard, Kevin, Lefevre, Pierre-Henri, Garnier, Ocean, Derraz, Imad, Dargazanli, Cyril, Gascou, Gregory, Riquelme, Carlos, Bonafe, Alain, Perrini, Paolo, Di Carlo, Davide Tiziano, Morganti, Riccardo, Le Corre, Marine, Pavillard, Frederique, Perrigault, Pierre-Francois, and Costalat, Vincent more...
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- 2021
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19. Usefulness of a single-parameter tool for the prediction of large vessel occlusion in acute stroke
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Leibinger, Franck, Allou, Thibaut, Van Damme, Laurène, Jebali, Chawki, Arquizan, Caroline, Farouil, Geoffroy, Laverdure, Alexandre, Gaillard, Nicolas, Ibanez, Majo, Smadja, Philippe, Dutray, Anais, Tardieu, Maxime, Nguyen Them, Ludovic, Ousji, Ali, Jurici, Snejana, Gascou, Gregory, Bensalah, Zoubir Mourad, Olivier, Nadège, Damon, Frederique, Chaabane, Wael, Fadat, Bénédicte, Lachcar, Marlène, Mas, Julie, Mourand, Isabelle, Ferraro, Adelaïde, Heve, Didier, Dumitrana, Adrian, Blenet, Jean-Christophe, Aptel, Sabine, Costalat, Vincent, Bonafe, Alain, Ortega, Laurent, and Sablot, Denis more...
- Published
- 2021
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20. Patency of the supraclinoid internal carotid artery branches after flow diversion treatment. A meta-analysis
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Cagnazzo, Federico, Lefevre, Pierre-Henri, Mantilla, Daniel, Rouchaud, Aymeric, Morganti, Riccardo, Perrini, Paolo, Carlo, Davide Di, Dargazanli, Cyril, Gascou, Gregory, Riquelme, Carlos, Bonafe, Alain, and Costalat, Vincent more...
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- 2019
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21. A proposed modern standardized technical approach for symptomatic chronic carotid total occlusion management
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Radu, Răzvan Alexandru, primary, Cagnazzo, Federico, additional, Schiphorst, Adrien Ter, additional, Machi, Paolo, additional, Dargazanli, Cyril, additional, Lefevre, Pierre-Henri, additional, Gascou, Gregory, additional, and Costalat, Vincent, additional more...
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- 2024
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22. White Matter Hyperintensity Burden and Collateral Circulation in Large Vessel Occlusion Stroke
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Derraz, Imad, Abdelrady, Mohamed, Gaillard, Nicolas, Ahmed, Raed, Cagnazzo, Federico, Dargazanli, Cyril, Lefevre, Pierre-Henri, Corti, Lucas, Riquelme, Carlos, Mourand, Isabelle, Gascou, Gregory, Bonafe, Alain, Arquizan, Caroline, and Costalat, Vincent more...
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- 2021
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23. Comparison of mechanical thrombectomy techniques in an in vitro stroke model: How to obtain a first pass recanalization?
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Gascou Gregory, Cagnazzo Federico, Pierre-Henri Lefevre, Dargazanli Cyril, Costalat Vincent, and Omer Faruk Eker
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging ,Neurology (clinical) - Abstract
Since mechanical thrombectomy (MT) has proven to be effective in the treatment of acute ischemic stroke (AIS), significant research has been dedicated to establishing procedural techniques offering best rate of first pass effect (FPE). In this study, we compared the efficacy of different techniques in vitro to achieve the first pass recanalisation (FPR).In vitro MT procedures were performed using a realistic silicone model of the human cerebral vasculature. The MT with stent retriever (SR) were performed with manual co-aspiration through the respective access catheter and intermediate catheter (IC), with Solumbra or partial retrieval techniques into the IC. Two SRs (Solitaire and EmboTrap) were selected to retrieve both red blood cells (RBC) rich and fibrin-rich clots. FPR rates were recorded for each case.Overall, 144 MT were performed. FPR rates using the partial retrieval and Solumbra technique were of 100% and 87%, respectively (p = 0.01). The rate of FPR was of 92% using the balloon-guide catheter (BGC) compared to 64% with the guide catheter (GC) (p = 0.0001). With an IC, no differences were found between using a BGC or a GC (87.9% vs 89,6%, p = 0.75). No significant difference was observed between the Embotrap and the Solitaire device for the rate of FPR (82% and 74%, respectively; p = 0.23).In this study, FPR rates were higher with the use of an IC associated with the partial retrieval technique, regardless the guide catheter, the SR, or the clot composition. The less effective technique was the association of GC and SR, without an IC. more...
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- 2023
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24. Safety and efficacy of braided stents as stent monotherapy for the treatment of small intracranial aneurysms
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Capirossi, Carolina, primary, Radu, Razvan A, additional, Gascou, Gregory, additional, Lefevre, Pierre-Henri, additional, Dargazanli, Cyril, additional, Machi, Paolo, additional, Costalat, Vincent, additional, and Cagnazzo, Federico, additional more...
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- 2023
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25. Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms
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Mendes Pereira, Vitor, primary, Rice, Hal, additional, De Villiers, Laetitia, additional, Sourour, Nader, additional, Clarencon, Frédéric, additional, Spears, Julian, additional, Tomasello, Alejandro, additional, Hernandez, David, additional, Cancelliere, Nicole M, additional, Liu, Xiao Yu Eileen, additional, Nicholson, Patrick, additional, Costalat, Vincent, additional, Gascou, Gregory, additional, Mordasini, Pasquale, additional, Gralla, Jan, additional, Martínez-Galdámez, Mario, additional, Galvan Fernandez, Jorge, additional, Killer-Oberpfalzer, Monika, additional, Liebeskind, David S, additional, Turner, Raymond D, additional, Blanc, Raphael, additional, and Piotin, Michel, additional more...
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- 2023
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26. O17/171 World’s first robotic assisted cerebral aneurysm embolization international trial
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Pereira, Vitor Mendes, primary, Rice, Hal, additional, Villiers, Laetitia, additional, Sourour, Nader, additional, Clarençon, Frédéric, additional, Spears, Julian, additional, Tomasello, Alejandro, additional, Ribo, Marc, additional, Costalat, Vincent, additional, Gascou, Gregory, additional, Mordasini, Pasquale, additional, Gralla, Jan, additional, Galdamez, Mario Martinez, additional, Galván-Fernández, Jorge, additional, Killer-Oberpfalzer, Monika, additional, Turner, Raymond, additional, Blanc, Raphael, additional, and Piotin, Michel, additional more...
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- 2023
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27. Diffusion weighted imaging and time in acute ischemic stroke, is there any relation?
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Mantilla-García, Daniel, Mourand, Isabelle, Gascou, Gregory, Riquelme, Carlos, Dargazanli, Cyril, López-Jaramillo, Patricio, Camacho, Paul A., Eker, Omer, Bonafé, Alain, and Costalat, Vincent
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- 2017
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28. Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms.
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Mendes Pereira, Vitor, Rice, Hal, De Villiers, Laetitia, Sourour, Nader, Clarencon, Frédéric, Spears, Julian, Tomasello, Alejandro, Hernandez, David, Cancelliere, Nicole M., Xiao Yu Eileen Liu, Nicholson, Patrick, Costalat, Vincent, Gascou, Gregory, Mordasini, Pasquale, Gralla, Jan, Martínez-Galdámez, Mario, Galvan Fernandez, Jorge, Killer-Oberpfalzer, Monika, Liebeskind, David S., and Turner, Raymond D. more...
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INTRACRANIAL aneurysm surgery ,SURGICAL robots ,INTRACRANIAL aneurysms ,CEREBRAL angiography ,PEARSON correlation (Statistics) ,PATIENT safety ,STATISTICAL significance ,RESEARCH funding ,THERAPEUTIC embolization ,ENDOVASCULAR surgery ,TREATMENT effectiveness ,SURGICAL stents ,DESCRIPTIVE statistics ,LONGITUDINAL method ,RESEARCH ,CONFIDENCE intervals ,DATA analysis software - Abstract
Background Robotic-assisted neurointervention was recently introduced, with implications that it could be used to treat neurovascular diseases. Objective To evaluate the effectiveness and safety of the robotic-assisted platform CorPath GRX for treating cerebral aneurysms. Methods This prospective, international, multicenter study enrolled patients with brain aneurysms that required endovascular coiling and/or stent-assisted coiling. The primary effectiveness endpoint was defined as successful completion of the robotic-assisted endovascular procedure without any unplanned conversion to manual treatment with guidewire or microcatheter navigation, embolization coil(s) or intracranial stent(s) deployment, or an inability to navigate vessel anatomy. The primary safety endpoint included intraprocedural and periprocedural events. Results The study enrolled 117 patients (74.4% female) with mean age of 56.6 years from 10 international sites,. Headache was the most common presenting symptom in 40/117 (34.2%) subjects. Internal carotid artery was the most common location (34/122, 27.9%), and the mean aneurysm height and neck width were 5.7±2.6 mm and 3.5±1.4 mm, respectively. The overall procedure time was 117.3±47.3 min with 59.4±32.6 min robotic procedure time. Primary effectiveness was achieved in 110/117 (94%) subjects with seven subjects requiring conversion to manual for procedure completion. Only four primary safety events were recorded with two intraprocedural aneurysm ruptures and two strokes. A Raymond-Roy Classification Scale score of 1 was achieved in 71/110 (64.5%) subjects, and all subjects were discharged with a modified Rankin Scale score of ≤2. Conclusions This first-of-its-kind robotic-assisted neurovascular trial demonstrates the effectiveness and safety of the CorPath GRX System for endovascular embolization of cerebral aneurysm procedures. [ABSTRACT FROM AUTHOR] more...
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- 2024
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29. Flow Diverters for Intracranial Aneurysms: The DIVERSION National Prospective Cohort Study
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Gory, Benjamin, Berge, Jerome, Bonafé, Alain, Pierot, Laurent, Spelle, Laurent, Piotin, Michel, Biondi, Alessandra, Cognard, Christophe, Mounayer, Charbel, Sourour, Nader, Barbier, Charlotte, Desal, Hubert, Herbreteau, Denis, Chabert, Emmanuel, Brunel, Hervé, Ricolfi, Frédéric, Anxionnat, René, Decullier, Evelyne, Huot, Laure, Turjman, Francis, Barreau, Xavier, Menegon, Patrice, Marnat, Gaultier, Costalat, Vincent, Gascou, Gregory, Dargazanli, Cyril, Soize, Sébastien, Metaxas, Georges, Moret, Jacques, Ikka, Léon, Caroff, Jildaz, Rouchaud, Aymeric, Mihaela, Christian, Benachour, Nidal, Blanc, Raphaël, Redjem, Hocine, Pomero, Elisa, Januel, Anne Christine, Darcout, Julien, Guenego, Adrien, Tall, Philippe, Bonneville, Fabrice, Saleme, Suzana, Clarençon, Frédéric, Bourcier, Romain, Narata, Ana Paula, Bibi, Richard, Bracard, Serge, Derelle, Anne-Laure, Tonnelet, Romain, Liao, Liang, Kulcsar, Zsolt, and Taschner, Christian more...
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- 2019
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30. Efficacy and safety of low dose intravenous cangrelor in a consecutive cohort of patients undergoing neuroendovascular procedures.
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Cagnazzo, Federico, Radu, Răzvan Alexandru, Derraz, Imad, Lefevre, Pierre Henri, Dargazanli, Cyril, Machi, Paolo, Morganti, Riccardo, Gascou, Gregory, Fendeleur, Julien, Rapido, Francesca, and Costalat, Vincent more...
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DRUG efficacy ,THROMBOSIS ,INTRAVENOUS therapy ,BLOOD vessels ,NEUROSURGERY ,RETROSPECTIVE studies ,PLATELET aggregation inhibitors ,DESCRIPTIVE statistics ,ENDOVASCULAR surgery ,COMPUTED tomography ,DRUG side effects ,PATIENT safety ,HEMORRHAGE - Abstract
Background Cangrelor is an intravenous P2Y12 inhibitor with rapid onset and fast offset of antiplatelet action. Dose adjusted cangrelor based on platelet function testing is suggested to be advantageous for use during neuroendovascular procedures. In this study, we aimed to assess the efficacy and safety of this strategy. Methods This retrospective study included consecutive patients who received low dose intravenous cangrelor (5 µg/kg; infusion 1 µg/kg/min) for ruptured (RIA) and unruptured (UIA) intracranial aneurysms, and acute ischemic stroke (AIS). Indications were acute stenting or intraluminal thrombus. Outcomes were assessed at 24 hours by brain CT and CT angiography. The primary efficacy outcome was the rate of stent occlusion or persistent intraluminal thrombus. The primary safety outcome was the rate of major hemorrhages. Results 101 patients (56 men; median age (IQR) 59 (51-70) years) received low dose cangrelor for acute stenting (79/101 (78%)) and intraprocedural thrombus (22/101 (22%)). Overall, 5 (4.9%) patients experienced stent occlusion within 24 hours (RIA 3/28; AIS 2/52). There were no cases of failure among UIA patients. Stent mis-opening (fish mouthing or stenosis >50%) was significantly associated with stent occlusion (P<0.001). The overall rate of major hemorrhage was 2% (2/101), which occurred in AIS patients. Platelet reactivity unit (PRU) values were lower in those presenting with major hemorrhage (PRU 4 (SD 1.4) vs PRU 60 (SD 63); P=0.043). Mortality rate after cangrelor related hemorrhage was 1%. Conclusions Low dose cangrelor appears to be effective in preventing stent thrombosis and arterial patency with a low hemorrhagic risk. [ABSTRACT FROM AUTHOR] more...
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- 2024
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31. Patient Selection in a Pragmatic Study on the Management of Patients with Brain Arteriovenous Malformations
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Raymond, Jean, primary, Benomar, Anass, additional, Gentric, Jean-Christophe, additional, Magro, Elsa, additional, Nico, Lorena, additional, Bacchus, Emma, additional, Klink, Ruby, additional, Iancu, Daniela, additional, Weill, Alain, additional, Roy, Daniel, additional, Bojanowski, Michel W., additional, Chaalala, Chiraz, additional, Eker, Omer, additional, Pelissou-Guyotat, Isabelle, additional, Piotin, Michel, additional, Aldea, Sorin, additional, Barbier, Charlotte, additional, Gaberel, Thomas, additional, Papagiannaki, Chrysanthi, additional, Derrey, Stéphane, additional, Nguyen, Thanh N., additional, Abdalkader, Mohamad, additional, Cognard, Christophe, additional, Januel, Anne-Christine, additional, Sabatier, Jean-François, additional, Jecko, Vincent, additional, Barreau, Xavier, additional, Costalat, Vincent, additional, Le Corre, Marine, additional, Gauvrit, Jean-Yves, additional, Morandi, Xavier, additional, Biondi, Alessandra, additional, Thines, Laurent, additional, Desal, Hubert, additional, Bourcier, Romain, additional, Beaujeux, Rémy, additional, Proust, François, additional, Viard, Geraldine, additional, Gevry, Guylaine, additional, Darsaut, Tim E., additional, Raymond, Jean, additional, O'Kelly, Cian J., additional, Chow, Michael MC., additional, Findlay, J. Max, additional, Rempel, Jeremy L., additional, Fahed, Robert, additional, Lesiuk, Howard, additional, Drake, Brian, additional, Santos, Marlene dos, additional, Nonent, Michel, additional, Ognard, Julien, additional, El-Aouni, Mourad Cheddad, additional, Seizeur, Romuald, additional, Timsit, Serge, additional, Pradier, Olivier, additional, Boursier, Romain, additional, Thillays, François, additional, Roualdes, Vincent, additional, Blanc, Raphael, additional, Calviere, Lionel, additional, Gauvrit, Jean Yves, additional, Raoult, Hélène, additional, Eugene, François, additional, Le Bras, Anthony, additional, Ferre, Jean-Christophe, additional, Paya, Christophe, additional, Lecouillard, Isabelle, additional, Nouhaud, Elodie, additional, Ronziere, Thomas, additional, Trystram, Denis, additional, Naggara, Olivier, additional, Rodriguez-Regent, Christine, additional, Kerleroux, Basile, additional, Emery, Evelyne, additional, Touze, Emmanuel, additional, Riva, Roberto, additional, Pellisou-Guyotat, Isabelle, additional, Guyotat, Jacques, additional, Berhouma, Monsef, additional, Dumot, Chloé, additional, Bougaci, Nassim, additional, Charbonnier, Guillaume, additional, Bracard, Serge, additional, Anxionnat, René, additional, Gory, Benjamin, additional, Civit, Thierry, additional, Bernier-Chastagner, Valérie, additional, Marnat, Gaultier, additional, Penchet, Guillaume, additional, Gimbert, Edouard, additional, Huchet, Aymeri, additional, Herbreteau, Denis, additional, Boulouis, Grégoire, additional, Bibi, Richard, additional, Ifergan, Héloïse, additional, Janot, Kévin, additional, Velut, Stéphane, additional, Brunel, Hervé, additional, Roche, Pierre-Hugues, additional, Graillon, Thomas, additional, Peyriere, Hadrien, additional, Kaya, Jean-Marc, additional, Touta, Adamou, additional, Troude, Lucas, additional, Boissonneau, Sébastien, additional, Clarençon, Frédéric, additional, Shotar, Eimad, additional, Sourour, Nader, additional, Lenck, Stéphanie, additional, Premat, Kévin, additional, Boch, Anne-Laure, additional, Cornu, Philippe, additional, Nouet, Aurélien, additional, Bonafe, Alain, additional, Dargazanli, Cyril, additional, Gascou, Gregory, additional, Lefevre, Pierre-Henri, additional, Riquelme, Carlos, additional, Pop, Raoul, additional, Cebula, Hélène, additional, Ollivier, Irène, additional, Spatola, Giorgio, additional, Spell, Laurent, additional, Chalumeau, Vanessa, additional, Gallas, Sophie, additional, Ikka, Léon, additional, Mihalea, Cristian, additional, Ozanne, Augustin, additional, Caroff, Jildaz, additional, Chabert, Emmanuel, additional, Mounayer, Charbel, additional, Rouchaud, Aymeric, additional, Caire, François, additional, Ricolfi, Frédéric, additional, Thouant, Pierre, additional, Cao, Catherine, additional, Mourier, Klaus-Luc, additional, Farah, Walid, additional, Huynh, Thien, additional, Tawk, Rabih G., additional, Carlson, Andrew P., additional, Oliveira Silva, Luciana Alves, additional, de Lima Froio, Nayara, additional, Silva, Gisele Sampaio, additional, Mont’Alverne, Francisco J.A., additional, Martins, Jose Luri, additional, Mendes, George Nunes, additional, and Miranda, Rodrigo Rivera, additional more...
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- 2023
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32. Efficacy and safety of low dose intravenous cangrelor in a consecutive cohort of patients undergoing neuroendovascular procedures
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Cagnazzo, Federico, primary, Radu, Răzvan Alexandru, additional, Derraz, Imad, additional, Lefevre, Pierre Henri, additional, Dargazanli, Cyril, additional, Machi, Paolo, additional, Morganti, Riccardo, additional, Gascou, Gregory, additional, Fendeleur, Julien, additional, Rapido, Francesca, additional, and Costalat, Vincent, additional more...
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- 2023
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33. Complete recanalization predicts favorable outcome in patients with distal M2-M3 middle cerebral artery occlusions following endovascular thrombectomy
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ABDELRADY, Mohamed, primary, DERRAZ, Imad, additional, DARGAZANLI, Cyril, additional, AOUNI, Mourad CHEDDAD EL, additional, LEFEVRE, Pierre-Henri, additional, CAGNAZZO, Federico, additional, RIQUELME, Carlos, additional, GASCOU, Gregory, additional, ARQUIZAN, Caroline, additional, MOURAND, Isabelle, additional, SALEM, Douraied BEN, additional, COSTALAT, Vincent, additional, GENTRIC, Jean-Christophe, additional, and OGNARD, Julien, additional more...
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- 2022
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34. Endovascular treatment of brain arteriovenous malformations: clinical outcomes of patients included in the registry of a pragmatic randomized trial
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Raymond, Jean, primary, Gentric, Jean-Christophe, additional, Magro, Elsa, additional, Nico, Lorena, additional, Bacchus, Emma, additional, Klink, Ruby, additional, Cognard, Christophe, additional, Januel, Anne-Christine, additional, Sabatier, Jean-François, additional, Iancu, Daniela, additional, Weill, Alain, additional, Roy, Daniel, additional, Bojanowski, Michel W., additional, Chaalala, Chiraz, additional, Barreau, Xavier, additional, Jecko, Vincent, additional, Papagiannaki, Chrysanthi, additional, Derrey, Stéphane, additional, Shotar, Eimad, additional, Cornu, Philippe, additional, Eker, Omer F., additional, Pelissou-Guyotat, Isabelle, additional, Piotin, Michel, additional, Aldea, Sorin, additional, Beaujeux, Rémy, additional, Proust, François, additional, Anxionnat, René, additional, Costalat, Vincent, additional, Corre, Marine Le, additional, Gauvrit, Jean-Yves, additional, Morandi, Xavier, additional, Brunel, Hervé, additional, Roche, Pierre-Hugues, additional, Graillon, Thomas, additional, Chabert, Emmanuel, additional, Herbreteau, Denis, additional, Desal, Hubert, additional, Trystram, Denis, additional, Barbier, Charlotte, additional, Gaberel, Thomas, additional, Nguyen, Thanh N., additional, Viard, Geraldine, additional, Gevry, Guylaine, additional, Darsaut, Tim E., additional, _, _, additional, Raymond, Jean, additional, O’Kelly, Cian J., additional, Chow, Michael M. C., additional, Findlay, J. Max, additional, Rempel, Jeremy L., additional, Fahed, Robert, additional, Lesiuk, Howard, additional, Drake, Brian, additional, Santos, Marlene dos, additional, Nonent, Michel, additional, Ognard, Julien, additional, El-Aouni, Mourad Cheddad, additional, Seizeur, Romuald, additional, Timsit, Serge, additional, Pradier, Olivier, additional, Boursier, Romain, additional, Thillays, François, additional, Roualdes, Vincent, additional, Blanc, Raphael, additional, Calviere, Lionel, additional, Gauvrit, Jean Yves, additional, Raoult, Hélène, additional, Eugene, François, additional, Bras, Anthony Le, additional, Ferre, Jean-Christophe, additional, Paya, Christophe, additional, Lecouillard, Isabelle, additional, Nouhaud, Elodie, additional, Ronziere, Thomas, additional, Naggara, Olivier, additional, Rodriguez-Regent, Christine, additional, Kerleroux, Basile, additional, Emery, Evelyne, additional, Touze, Emmanuel, additional, Riva, Roberto, additional, Pellisou-Guyotat, Isabelle, additional, Guyotat, Jacques, additional, Berhouma, Monsef, additional, Dumot, Chloé, additional, Biondi, Alessandra, additional, Thines, Laurent, additional, Bougaci, Nassim, additional, Charbonnier, Guillaume, additional, Bracard, Serge, additional, Gory, Benjamin, additional, Civit, Thierry, additional, Bernier-Chastagner, Valérie, additional, Marnat, Gaultier, additional, Penchet, Guillaume, additional, Gimbert, Edouard, additional, Huchet, Aymeri, additional, Boulouis, Grégoire, additional, Bibi, Richard, additional, Ifergan, Héloïse, additional, Janot, Kévin, additional, Velut, Stéphane, additional, Peyriere, Hadrien, additional, Kaya, Jean-Marc, additional, Touta, Adamou, additional, Troude, Lucas, additional, Boissonneau, Sébastien, additional, Clarençon, Frédéric, additional, Sourour, Nader, additional, Lenck, Stéphanie, additional, Premat, Kévin, additional, Boch, Anne-Laure, additional, Nouet, Aurélien, additional, Bonafe, Alain, additional, Dargazanli, Cyril, additional, Gascou, Gregory, additional, Lefevre, Pierre-Henri, additional, Riquelme, Carlos, additional, Pop, Raoul, additional, Cebula, Hélène, additional, Ollivier, Irène, additional, Spatola, Giorgio, additional, Spell, Laurent, additional, Chalumeau, Vanessa, additional, Gallas, Sophie, additional, Ikka, Léon, additional, Mihalea, Cristian, additional, Ozanne, Augustin, additional, Caroff, Jildaz, additional, Mounayer, Charbel, additional, Rouchaud, Aymeric, additional, Caire, François, additional, Ricolfi, Frédéric, additional, Thouant, Pierre, additional, Cao, Catherine, additional, Mourier, Klaus-Luc, additional, Farah, Walid, additional, Abdalkader, Mohamad, additional, Huynh, Thien, additional, Tawk, Rabih G., additional, Carlson, Andrew P., additional, Silva, Luciana Alves Oliveira, additional, Froio, Nayara de Lima, additional, Silva, Gisele Sampaio, additional, Mont’Alverne, Francisco J. A., additional, Martins, Jose Luri, additional, Mendes, George Nunes, additional, and Miranda, Rodrigo Rivera, additional more...
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- 2022
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35. MRI Outcomes Achieved by Simple Flow Blockage Technique in Symptomatic Carotid Artery Stenosis Stenting
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Hak, Jean-François, primary, Arquizan, Caroline, additional, Cagnazzo, Federico, additional, Mahmoudi, Mehdi, additional, Collemiche, Francois-Louis, additional, Gascou, Gregory, additional, Lefevre, Pierre-Henry, additional, Derraz, Imad, additional, Labreuche, Julien, additional, Mourand, Isabelle, additional, Gaillard, Nicolas, additional, Corti, Lucas, additional, Charif, Mahmoud, additional, Costalat, Vincent, additional, and Dargazanli, Cyril, additional more...
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- 2022
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36. Surgical treatment of brain arteriovenous malformations: clinical outcomes of patients included in the registry of a pragmatic randomized trial
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Darsaut, Tim E., primary, Magro, Elsa, additional, Bojanowski, Michel W., additional, Chaalala, Chiraz, additional, Nico, Lorena, additional, Bacchus, Emma, additional, Klink, Ruby, additional, Iancu, Daniela, additional, Weill, Alain, additional, Roy, Daniel, additional, Sabatier, Jean-Francois, additional, Cognard, Christophe, additional, Januel, Anne-Christine, additional, Pelissou-Guyotat, Isabelle, additional, Eker, Omer, additional, Roche, Pierre-Hugues, additional, Graillon, Thomas, additional, Brunel, Hervé, additional, Proust, Francois, additional, Beaujeux, Rémy, additional, Aldea, Sorin, additional, Piotin, Michel, additional, Cornu, Philippe, additional, Shotar, Eimad, additional, Gaberel, Thomas, additional, Barbier, Charlotte, additional, Corre, Marine Le, additional, Costalat, Vincent, additional, Jecko, Vincent, additional, Barreau, Xavier, additional, Morandi, Xavier, additional, Gauvrit, Jean-Yves, additional, Derrey, Stéphane, additional, Papagiannaki, Chrysanthi, additional, Nguyen, Thanh N., additional, Abdalkader, Mohamad, additional, Tawk, Rabih G., additional, Huynh, Thien, additional, Viard, Geraldine, additional, Gevry, Guylaine, additional, Gentric, Jean-Christophe, additional, Raymond, Jean, additional, _, _, additional, Darsaut, Tim E., additional, Rempel, Jeremy L., additional, O’Kelly, Cian J., additional, Chow, Michael M. C., additional, Findlay, J. Max, additional, Fahed, Robert, additional, Lesiuk, Howard, additional, Drake, Brian, additional, Santos, Marlene dos, additional, Seizeur, Romuald, additional, Nonent, Michel, additional, Timsit, Serge, additional, Pradier, Olivier, additional, Ognard, Julien, additional, El-Aouni, Mourad Cheddad, additional, Desal, Hubert, additional, Boursier, Romain, additional, Thillays, François, additional, Roualdes, Vincent, additional, Blanc, Raphael, additional, Sabatier, Jean-François, additional, Calviere, Lionel, additional, Gauvrit, Jean Yves, additional, Lecouillard, Isabelle, additional, Nouhaud, Elodie, additional, Raoult, Hélène, additional, Eugene, François, additional, Bras, Anthony Le, additional, Ferre, Jean-Christophe, additional, Paya, Christophe, additional, Ronziere, Thomas, additional, Trystram, Denis, additional, Naggara, Olivier, additional, Rodriguez-Regent, Christine, additional, Kerleroux, Basile, additional, Emery, Evelyne, additional, Touze, Emmanuel, additional, Derrey, Stephane, additional, Pellisou-Guyotat, Isabelle, additional, Guyotat, Jacques, additional, Berhouma, Monsef, additional, Riva, Roberto, additional, Dumot, Chloé, additional, Biondi, Alessandra, additional, Thines, Laurent, additional, Charbonnier, Guillaume, additional, Bougaci, Nassim, additional, Bracard, Serge, additional, Anxionnat, René, additional, Bernier-Chastagner, Valérie, additional, Civit, Thierry, additional, Gory, Benjamin, additional, Penchet, Guillaume, additional, Gimbert, Edouard, additional, Marnat, Gaulthier, additional, Huchet, Aymeri, additional, Herbreteau, Denis, additional, Boulouis, Grégoire, additional, Velut, Stéphane, additional, Bibi, Richard, additional, Ifergan, Héloïse, additional, Janot, Kévin, additional, Peyriere, Hadrien, additional, Kaya, Jean-Marc, additional, Touta, Adamou, additional, Troude, Lucas, additional, Boissonneau, Sébastien, additional, Boch, Anne-Laure, additional, Clarençon, Frédéric, additional, Sourour, Nader, additional, Nouet, Aurélien, additional, Lenck, Stéphanie, additional, Premat, Kévin, additional, Bonafe, Alain, additional, Dargazanli, Cyril, additional, Gascou, Gregory, additional, Lefevre, Pierre-Henri, additional, Riquelme, Carlos, additional, Cebula, Hélène, additional, Ollivier, Irène, additional, Pop, Raoul, additional, Spatola, Giorgio, additional, Spelle, Laurent, additional, Chalumeau, Vanessa, additional, Gallas, Sophie, additional, Ikka, Léon, additional, Mihalea, Cristian, additional, Ozanne, Augustin, additional, Caroff, Jildaz, additional, Chabert, Emmanuel, additional, Mounayer, Charbel, additional, Rouchaud, Aymeric, additional, Caire, Francois, additional, Ricolfi, Frédéric, additional, Cao, Catherine, additional, Mourier, Klaus-Luc, additional, Thouant, Pierre, additional, Farah, Walid, additional, Carlson, Andrew P., additional, Silva, Luciana Alves Oliveira, additional, Froio, Nayara de Lima, additional, Silva, Gisele Sampaio, additional, Mont’Alverne, Francisco J. A., additional, Martins, Jose Luri, additional, Mendes, George Nunes, additional, and Miranda, Rodrigo Rivera, additional more...
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- 2022
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37. Endovascular therapy with or without intravenous thrombolysis in acute stroke with tandem occlusion
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Anadani, Mohammad, Marnat, Gaultier, Consoli, Arturo, Papanagiotou, Panagiotis, Nogueira, Raul, Spiotta, Alejandro, Bourcier, Romain, Kyheng, Maeva, Labreuche, Julien, Siddiqui, Adnan, Ribo, Marc, de Havenon, Adam, Fischer, Urs, Sibon, Igor, Dargazanli, Cyril, Arquizan, Caroline, Cognard, Christophe, Olivot, Jean Marc, Anxionnat, René, Audibert, Gérard, Mazighi, Mikael, Blanc, Raphaël, Lapergue, Bertrand, Richard, Sébastien, Gory, Benjamin, Turjman, Francis, Piotin, Michel, Steglich-Arnholm, Henrik, Holtmannspötter, Markus, Taschner, Christian, Eiden, Sebastian, Haussen, Diogo C., Muhammad, Waqas, Boutchakova, Maria, Dorn, Franziska, Killer-Oberpfalzer, Monika, Mangiafico, Salvatore, Psychogios, Marios-Nikos, Labeyrie, Marc-Antoine, Biondi, Alessandra, Bracard, Serge, Andrew Grossberg, Jonathan, Guenego, Adrien, Darcourt, Julien, Vukasinovic, Isabelle, Pomero, Elisa, Davies, Jason, Renieri, Leonardo, Hecker, Corentin, Muchada Muchada, Maria, Rodesch, Georges, Houdart, Emmanuel, Lockau, Johanna, Kastrup, Andreas, Redjem, Hocine, Behme, Daniel, Shallwani, Hussain, Christopher, Maurer, Mione, Gioia, Humbertjean, Lisa, Riou-Comte, Nolwenn, Zhu, François, Borderelle, Anne-Laure, Liao, Liang, Escalard, Simon, Desilles, Jean-Philippes, Ciccio, Gabriele, Smajda, Stanislas, Obadia, Mikael, Sabben, Candice, Corabianu, Ovide, de Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Éric, Garcia, Pierre-Yves, Taylor, Guillaume, Ben Maacha, Malek, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Ajili, Nadia, Weisenburger, David, Gorza, Lucas, Coskun, Oguzhan, Di Maria, Federico, Rodesh, Georges, Leguen, Morgan, Gratieux, Julie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Marinier, Sylvie, Gariel, Florent, Barreau, Xavier, Berge, Jérôme, Veunac, Louis, Menegon, Patrice, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Tourdias, Thomas, Liegey, Jean-Sébastien, Daumas-Duport, Benjamin, Alexandre, Pierre-Louis, Roy, Monica, Lenoble, Cédric, L'Allinec, Vincent, Girot, Jean-Baptiste, Desal, Hubert, Braun, Marc, Derelle, Anne-Laure, Tonnelet, Romain, Schmitt, Emmanuelle, Planel, Sophie, Lacour, Jean-Christophe, Hossu, Gabriela, Beaumont, Marine, Bailang, Mitchelle, Reitter, Marie, Masson, Agnès, Alb, Lionel, Tabarna, Adriana, Voicu, Marcela, Podar, Iona, Brezeanu, Madalina, Costalat, Vincent, Gascou, Gregory, Lefevre, Pierre-Henri, Derraz, Imad, Riquelme, Carlos, Gaillard, Nicolas, Mourand, Isabelle, Corti, Lucas, Washington University School of Medicine in St. Louis, Washington University in Saint Louis (WUSTL), Medical University of South Carolina [Charleston] (MUSC), Département de Neuro-Radiologie [Bordeaux] (DNR - Bordeaux), CHU Bordeaux [Bordeaux], Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Hôpital Foch [Suresnes], National and Kapodistrian University of Athens (NKUA), Emory University School of Medicine, Emory University [Atlanta, GA], Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille, University at Buffalo [SUNY] (SUNY Buffalo), State University of New York (SUNY), Vall d'Hebron University Hospital [Barcelona], University of Utah, Inselspital Bern, Service de neurologie [Bordeaux], CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Neuroradiologie [Hôpital Gui de Chauliac], Hôpital Gui de Chauliac [Montpellier], Neurochirurgie [Hôpital Gui de Chauliac], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [Montpellier], Neuroradiologie Diagnostique et Thérapeutique [Toulouse], Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Hôpital Rothschild [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de neurologie [CHRU Nancy], Service Neuroradiologie diagnostique et interventionnelle [Hôpital Foch], Nantes Université - pôle Santé, Nantes Université (Nantes Univ), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Hôpital Gui de Chauliac [CHU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [CHU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service Neuroradiologie Diagnostique et Thérapeutique [CHU Toulouse], Pôle imagerie médicale [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Département de Neurologie [Toulouse], Institut des Neurosciences [Toulouse], Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT), CHU Rothschild [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Institut de Génomique Fonctionnelle (IGF), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS) more...
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medicine.medical_specialty ,medicine.medical_treatment ,Hemorrhage ,[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery ,[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine ,030204 cardiovascular system & hematology ,Endovascular therapy ,Brain Ischemia ,03 medical and health sciences ,0302 clinical medicine ,Fibrinolytic Agents ,Modified Rankin Scale ,medicine.artery ,Internal medicine ,Occlusion ,[INFO.INFO-IM]Computer Science [cs]/Medical Imaging ,medicine ,Humans ,Thrombolytic Therapy ,Stroke ,Ischemic Stroke ,Thrombectomy ,business.industry ,Cerebral infarction ,Endovascular Procedures ,General Medicine ,Thrombolysis ,medicine.disease ,3. Good health ,Treatment Outcome ,Propensity score matching ,Cardiology ,[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,Surgery ,Neurology (clinical) ,Internal carotid artery ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,030217 neurology & neurosurgery - Abstract
BackgroundEndovascular therapy (EVT) is effective and safe in patients with tandem occlusion. The benefit of intravenous thrombolysis (IVT) prior to EVT in acute tandem occlusion is debatable.ObjectiveTo compare EVT alone with EVT plus IVT in patients with acute ischemic stroke due to anterior circulation tandem occlusions.MethodsThis is an individual patient pooled analysis of the Thrombectomy In TANdem lesions (TITAN) and Endovascular Treatment in Ischemic Stroke (ETIS) Registries. Patients were divided into two groups based on prior IVT treatment: (1) IVT+ group, which included patients who received IVT prior to EVT, (2) IVT− group, which included patients who did not receive IVT prior to EVT. Propensity score (inverse probability of treatment weighting (IPTW)) was used to reduce baseline between-group differences. The primary outcome was favorable outcome—that is, modified Rankin Scale (mRS) score 0 to 2 at 90 days.ResultsOverall, 602 consecutive patients with an acute stroke with tandem occlusion were included (380 and 222 in the bridging therapy and EVT alone groups, respectively). Onset to imaging time was shorter in the IVT+ group (median 103 vs 140 min). In contrast, imaging to puncture time was longer in the IVT+ group (median 107 vs 91 min). In IPTW analysis, the IVT+ group had higher odds of favorable outcome, excellent outcome (90-day mRS score 0–1), and successful reperfusion (modified Thrombolysis in Cerebral Infarction score 2b/3 at the end of EVT). There was no difference in the risk of significant hemorrhagic complications between groups. In secondary analysis of patients treated with acute cervical internal carotid artery stenting, bridging therapy was associated with higher odds of favorable outcome and lower odds of mortality at 90 days.ConclusionsOur results suggest that bridging therapy in patients with acute ischemic stroke due to anterior tandem occlusion is safe and may improve functional outcome, even in the setting of acute cervical internal carotid artery stenting during EVT. more...
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- 2021
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38. Favorable revascularization therapy in patients with ASPECTS ≤ 5 on DWI in anterior circulation stroke
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Mourand, Isabelle, Abergel, Eitan, Mantilla, Daniel, Ayrignac, Xavier, Sacagiu, Tzvika, Eker, Omer Faruk, Gascou, Gregory, Dargazanli, Cyril, Riquelme, Carlos, Moynier, Marinette, Bonafé, Alain, Arquizan, Caroline, and Costalat, Vincent more...
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- 2018
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39. Negative susceptibility vessel sign might be predictive of complete reperfusion in patients with acute basilar artery occlusion managed with thrombectomy
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Abdelrady, Mohamed, Derraz, Imad, Lefevre, Pierre-Henri, Cagnazzo, Federico, Gascou, Gregory, Arquizan, Caroline, Gentric, Jean-Christophe, Mourand, Isabelle, Dargazanli, Cyril, Ognard, Julien, Costalat, Vincent, Riquelme, Carlos, Mahmoudi, Mehdi, Corti, Lucas, Gaillard, Nicolas, Cheddad El Aouni, Mourad, Ben Salem, Douraied, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Neuroradiologie [Hôpital Gui de Chauliac], Hôpital Gui de Chauliac [CHU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Hôpital Universitaire Carémeau [Nîmes] (CHU Nîmes), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Laboratoire de Traitement de l'Information Medicale (LaTIM), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO), LaBoratoire d'Imagerie biOmédicale MultimodAle Paris-Saclay (BIOMAPS), Service Hospitalier Frédéric Joliot (SHFJ), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) more...
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MESH: Aged ,Ischemic stroke ,MESH: Humans ,MESH: Arterial Occlusive Diseases ,MESH: Endovascular Procedures ,[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging ,MESH: Brain Ischemia ,MESH: Retrospective Studies ,[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine ,General Medicine ,Atherosclerosis ,MESH: Male ,MESH: Prospective Studies ,MESH: Stroke ,MESH: Atherosclerosis ,MESH: Reperfusion ,Magnetic resonance imaging ,MESH: Basilar Artery ,MESH: Thrombectomy ,Radiology, Nuclear Medicine and imaging ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,Thrombectomy ,MESH: Treatment Outcome - Abstract
International audience; Objectives: Negative susceptibility vessel sign (SVS) on pre-thrombectomy MRI has been linked to fibrin-rich thrombus and difficult retrieval in anterior ischemic stroke. However, its impact in posterior circulation-large vessel occlusion stroke (PC-LVOS) has not yet been elucidated. We aim to investigate the relationship of SVS parameters with stroke subtypes and their influence on angiographic and functional outcomes.Methods: Prospective thrombectomy registries at two-comprehensive stroke centers were retrospectively reviewed between January 2015 and December 2019 for consecutive MRI-selected patients with PC-LVOS. Two groups were assigned by two independent readers, based on the presence or absence of the SVS (SVS +, SVS -) on MRI-GRE sequence. Multivariate logistic regression analysis was utilized to study primarily the impact of the SVS on the rate of complete recanalization (defined as mTICI 2c/3) at the final series following endovascular thrombectomy (EVT) and whether or not it might influence the efficacy of the frontline EVT strategy. Secondarily, we studied whether the absence of the SVS was predictive of the rate of 90-day functional independence (defined as mRS score < 2). Lastly, both qualitative (SVS +, SVS-) and quantitative (SVS length and diameter) parameters of the SVS were analyzed in association with the puncture to recanalization interval and various stroke etiological subtypes based on TOAST criteria.Results: Among 1823 patients, 116 were qualified for final analysis (median age, 68 (59-75) years; male, 65%); SVS was detected in 62.9% (73/116) of cases. SVS length was an independent predictor of procedural duration (p = .01) whilst two-layered SVS was inversely associated with the atherosclerosis etiological subtype (aOR = 0.27, 95% CI 0.08-0.89; p = .03). Successful recanalization was achieved in 82% (60/73) vs. 86% (37/43), p = .80 of patients with SVS (+, -) respectively. Only in SVS (+), stentriever (RR 0.59 (0.4-0.88), p = .009), and contact-aspiration (RR 0.82 (0.7-0.96), p = .01) achieved a lower rate of successful recanalization compared to combined technique. SVS (-) was significantly associated with a higher rate of mTICI 2c/3 (aOR = 4.444; 95% CI 1.466-13.473; p = .008) and showed an indirect effect of 9% towards functional independence mediated by mTICI 2c/3.Conclusion: SVS parameters in PC-LVOS might predict stroke subtype and indirectly influence the functional outcome by virtue of complete recanalization.Key points: • Negative susceptibility vessel sign (SVS) in patients with basilar occlusion independently predict complete recanalization that indirectly instigated a 3-month favorable outcome following thrombectomy. • The longer the SVS, the higher likelihood of large artery atherosclerosis and the longer the thrombectomy procedure. • Two-layered SVS might be negatively associated with the presence of atherosclerosis, yet already-known limitations of TOAST classification and the absence of pathological analysis should be taken into consideration. more...
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- 2022
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40. Angioplasty, stenting, or both — rescue maneuvers and reperfusion after endovascular therapy for intracranial atherosclerosis-related occlusion.
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Abdelrady, Mohamed, Rodriguez, José, Dargazanli, Cyril, Lefevre, Pierre-Henri, Ognard, Julien, Murias, Eduardo, Chaviano, Juan, Gentric, Jean-Christophe, Ben Salem, Douraied, Mourand, Isabelle, Arquizan, Caroline, Derraz, Imad, Vega, Pedro, Costalat, Vincent, Cagnazzo, Federico, Jimenez, José Maria, Riquelme, Carlos, Gascou, Gregory, Corti, Lucas, and Gaillard, Nicolas more...
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STROKE ,CONFIDENCE intervals ,INTRACRANIAL hemorrhage ,SURGICAL stents ,RETROSPECTIVE studies ,TREATMENT effectiveness ,THROMBECTOMY ,DESCRIPTIVE statistics ,ENDOVASCULAR surgery ,REPERFUSION ,CEREBRAL arteriosclerosis ,ANGIOPLASTY ,LONGITUDINAL method ,DISEASE risk factors - Abstract
Purpose: Data concerning reperfusion strategies of intracranial atherosclerosis-related occlusion (ICARO) and clinico-angiographic outcomes remain scarce, particularly in Caucasians. We aim to compare the reperfusion rate and functional outcome between reperfusion strategies in the setting of the ICARO. Methods: Retrospective analysis of prospectively maintained endovascular thrombectomy (EVT) registries at three high-volume stroke centers were retrospectively analyzed for consecutive ICARO patients from January 2015 to December 2019. We defined ICARO as any fixed high-degree (> 70%) focal narrowing or stenosis of any degree with a perpetual tendency for reocclusion. We categorized reperfusion strategies into four groups: EVT [group 1], balloon angioplasty [(BAp), group 2], placement of self-expandable stents [(SES), group 3], and BAp combined with implantation of SES; or direct placement of balloon mounted stents (BMS) [(BAp-SES/BMS), group 4]. We evaluated the association with the successful reperfusion [mTICI 2b − 3] and favorable outcome [mRS 0–2] with logistic regression analysis. Results: Out of 2550 EVT, 124 patients (median age, 70 (61–80) years; 76 men) with ICARO and 130 reperfusion attempts [36 EVT, 38 BAp, 17 SES, and 39 BAp + SES/BMS] were analyzed. SES implantation showed the highest frequency of post-procedural symptomatic intracranial hemorrhage [(18%, 3/17), p =.03]; however, we observed no significant differences in the mortality rate. Overall, we achieved successful reperfusion in 71% (92/130) and favorable outcomes in 42% (52/124) of the patients. BAp + SES/BMS was the only independent predictor of the final successful reperfusion [aOR, 4.488 (95% CI, 1.364–14.773); p =.01], which was significantly associated with the 90-day favorable outcome [aOR, 10.837 (95% CI, 3.609–32.541); p = <.001] after adjustment for confounding variables between the reperfusion strategies. Conclusion: Among patients with ICARO, the rescue angioplasty stenting effectively contributed to higher odds of successful reperfusion with no increased risk for intracranial hemorrhage. [ABSTRACT FROM AUTHOR] more...
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- 2023
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41. Frontline thrombectomy strategy and outcome in acute basilar artery occlusion
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Abdelrady, Mohamed, primary, Ognard, Julien, additional, Cagnazzo, Federico, additional, Derraz, Imad, additional, Lefevre, Pierre-Henri, additional, Riquelme, Carlos, additional, Gascou, Gregory, additional, Arquizan, Caroline, additional, Dargazanli, Cyril, additional, Cheddad El Aouni, Mourad, additional, Ben Salem, Douraied, additional, Mourand, Isabelle, additional, Costalat, Vincent, additional, and Gentric, Jean Christophe, additional more...
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- 2022
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42. Diversion-p64: results from an international, prospective, multicenter, single-arm post-market study to assess the safety and effectiveness of the p64 flow modulation device
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Bonafe, Alain, primary, Perez, Marta Aguilar, additional, Henkes, Hans, additional, Lylyk, Pedro, additional, Bleise, Carlos, additional, Gascou, Gregory, additional, Sirakov, Stanimir, additional, Sirakov, Alexander, additional, Stockx, Luc, additional, Turjman, Francis, additional, Petrov, Andrey, additional, Roth, Christian, additional, Narata, Ana-Paula, additional, Barreau, Xavier, additional, Loehr, Christian, additional, Berlis, Ansgar, additional, Pierot, Laurent, additional, Miś, Marcin, additional, Goddard, Tony, additional, Clifton, Andy, additional, Klisch, Joachim, additional, Wałęsa, Cezary, additional, Dall’Olio, Massimo, additional, Spelle, Laurent, additional, Clarencon, Frédéric, additional, Yakovlev, Sergey, additional, Keston, Peter, additional, Nuzzi, Nunzio Paolo, additional, Dima, Stefanita, additional, Wendl, Christina, additional, Willems, Tine, additional, and Schramm, Peter, additional more...
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- 2021
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43. Frontline thrombectomy strategy and outcome in acute basilar artery occlusion.
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Abdelrady, Mohamed, Ognard, Julien, Cagnazzo, Federico, Derraz, Imad, Lefevre, Pierre-Henri, Riquelme, Carlos, Gascou, Gregory, Arquizan, Caroline, Dargazanli, Cyril, El Aouni, Mourad Cheddad, Salem, Douraied Ben, Mourand, Isabelle, Costalat, Vincent, and Gentric, Jean Christophe more...
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ARTERIAL occlusions ,SAFETY ,CONFIDENCE intervals ,REVASCULARIZATION (Surgery) ,CEREBRAL infarction ,INTRACRANIAL hemorrhage ,MAGNETIC resonance imaging ,BASILAR artery ,TREATMENT effectiveness ,COMPARATIVE studies ,FUNCTIONAL assessment ,THROMBECTOMY ,DESCRIPTIVE statistics ,ODDS ratio - Abstract
Background Novel thrombectomy strategies emanate expeditiously day-by-day counting on access system, clot retriever device, proximity to and integration with the thrombus, and microcatheter disengagement. Nonetheless, the relationship between native thrombectomy strategies and revascularization success remains to be evaluated in basilar artery occlusion (BAO). Purpose To compare the safety and efficacy profile of key frontline thrombectomy strategies in BAO. Methods Retrospective analyses of prospectively maintained stroke registries at two comprehensive stroke centers were performed between January 2015 and December 2019. Patients with BAO selected after MR imaging were categorized into three groups based on the frontline thrombectomy strategy (contact aspiration (CA), stent retriever (SR), or combined (SR+CA)). Patients who experienced failure of clot retrieval followed by an interchanging strategy were categorized as a fourth (switch) group. Clinicoradiological features and procedural variables were compared. The primary outcome measure was the rate of complete revascularization (modified Thrombolysis in Cerebral Infarction (mTICI) grade 2c-3). Favorable outcome was defined as a 90 day modified Rankin Scale score of 0-2. Results Of 1823 patients, we included 128 (33 underwent CA, 35 SR, 35 SR +CA, and 25 switch techniques). Complete revascularization was achieved in 83/140 (59%) primarily analyzed patients. SR +CA was associated with higher odds of complete revascularization (adjusted OR 3.04, 95% CI 1.077 to 8.593, p=0.04) which was an independent predictor of favorable outcome (adjusted OR 2.73. 95% CI 1.152 to 6.458, p=0.02). No significant differences were observed for symptomatic intracranial hemorrhage, functional outcome, or mortality rate. Conclusion Among BAO patients, the combined technique effectively contributed to complete revascularization that showed a 90 day favorable outcome with an equivalent complication rate after thrombectomy. [ABSTRACT FROM AUTHOR] more...
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- 2023
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44. Chronic occlusion of the internal carotid artery: Endovascular revascularization technique of long occlusive lesions
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Cagnazzo, Federico, Dargazanli, Cyril, Lefevre, Pierre-Henri, Gascou, Gregory, Derraz, Imad, Riquelme, Carlos, Bonafe, Alain, and Costalat, Vincent
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- 2020
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45. WEB-assisted microwire navigation for the treatment of complex wide-neck intracranial aneurysms: Technical note
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Cagnazzo, Federico, Dargazanli, Cyril, Lefevre, Pierre-Henri, Gascou, Gregory, Derraz, Imad, Riquelme, Carlos, Bonafe, Alain, and Costalat, Vincent
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- 2020
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46. Safety and efficacy of the Silk flow diverter: Insight from the DIVERSION prospective cohort study
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Gariel, Florent, primary, Marnat, Gaultier, additional, Barreau, Xavier, additional, Menegon, Patrice, additional, Bourcier, Romain, additional, Pierot, Laurent, additional, Spelle, Lauren, additional, Bonafé, Alain, additional, Turjman, Francis, additional, Gory, Benjamin, additional, Berge, Jérôme, additional, Costalat, Vincent, additional, Gascou, Gregory, additional, Dargazanli, Cyril, additional, Soize, Sébastien, additional, Metaxas, Georges, additional, Moret, Jacques, additional, Ikka, Léon, additional, Caroff, Jildaz, additional, Rouchaud, Aymeric, additional, Mihaela, Christian, additional, Benachour, Nidal, additional, Piotin, Michel, additional, Blanc, Raphaël, additional, Redjem, Hocine, additional, Pomero, Elisa, additional, Biondi, Alessandra, additional, Cognard, Christophe, additional, Januel, Anne-Christine, additional, Darcourt, Jean, additional, Guenego, Adrien, additional, Tall, Philippe, additional, Bonneville, Fabrice, additional, Mounayer, Charbel, additional, Saleme, Suzana, additional, Sourour, Nader, additional, Clarençon, Frédéric, additional, Barbier, Charlotte, additional, Herbreteau, Denis, additional, Narata, Ana-Paula, additional, Bibi, Richard, additional, Bracard, Serge, additional, Anxionnat, René, additional, Derelle, Anne-Laure, additional, Tonnelet, Romain, additional, Liao, Liang, additional, Chabert, Emmanuel, additional, Brunel, Hervé, additional, Ricolfi, Frederic, additional, Desal, Hubert, additional, Kulcsar, Zsolt, additional, and Taschner, Christian, additional more...
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- 2021
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47. Diversion-p64: results from an international, prospective, multicenter, single-arm post-market study to assess the safety and effectiveness of the p64 flow modulation device.
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Bonafe, Alain, Perez, Marta Aguilar, Henkes, Hans, Lylyk, Pedro, Bleise, Carlos, Gascou, Gregory, Sirakov, Stanimir, Sirakov, Alexander, Stockx, Luc, Turjman, Francis, Petrov, Andrey, Roth, Christian, Narata, Ana-Paula, Barreau, Xavier, Loehr, Christian, Berlis, Ansgar, Pierot, Laurent, Miś, Marcin, Goddard, Tony, and Clifton, Andy more...
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MORTALITY prevention ,INTRACRANIAL aneurysm surgery ,RESEARCH ,STROKE ,SURGICAL stents ,DISEASE incidence ,MEDICAL equipment safety measures ,TREATMENT effectiveness ,COMPARATIVE studies ,DESCRIPTIVE statistics ,LONGITUDINAL method ,EVALUATION - Abstract
Background The use of flow diversion to treat intracranial aneurysms has increased in recent years. Objective To assess the safety and angiographic efficacy of the p64 flow modulation device. Methods Diversion-p64 is an international, prospective, multicenter, single-arm, study conducted at 26 centers. The p64 flow modulation device was used to treat anterior circulation aneurysms between December 2015 and January 2019. The primary safety endpoint was the incidence of major stroke or neurologic death at 3-6 months, with the primary efficacy endpoint being complete aneurysm occlusion (Raymond-Roy Occlusion Classification 1) on follow-up angiography. Results A total of 420 patients met the eligibility criteria and underwent treatment with the p64 flow modulation device (mean age 55±12.0 years, 86.2% female). Mean aneurysm dome width was 6.99±5.28 mm and neck width 4.47±2.28 mm. Mean number of devices implanted per patient was 1.06±0.47, with adjunctive coiling performed in 14.0% of the cases. At the second angiographic follow- up (mean 375±73 days), available for 343 patients (81.7%), complete aneurysm occlusion was seen in 287 (83.7%) patients. Safety data were available for 413 patients (98.3%) at the first follow-up (mean 145±43 days) with a composite morbidity/mortality rate of 2.42% (n=10). Conclusions Diversion- p64 is the largest prospective study using the p64 flow modulation device. The results of this study demonstrate that the device has a high efficacy and carries a low rate of mortality and permanent morbidity. [ABSTRACT FROM AUTHOR] more...
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- 2022
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48. Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Endovascular Thrombectomy
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Derraz, Imad, primary, Cagnazzo, Federico, additional, Gaillard, Nicolas, additional, Morganti, Riccardo, additional, Dargazanli, Cyril, additional, Ahmed, Raed, additional, Lefevre, Pierre-Henri, additional, Riquelme, Carlos, additional, Mourand, Isabelle, additional, Gascou, Gregory, additional, Bonafe, Alain, additional, Arquizan, Caroline, additional, and Costalat, Vincent, additional more...
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- 2021
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49. European Multicenter Study of ET-COVID-19
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Cagnazzo, Federico, primary, Piotin, Michel, additional, Escalard, Simon, additional, Maier, Benjamin, additional, Ribo, Marc, additional, Requena, Manuel, additional, Pop, Raoul, additional, Hasiu, Anca, additional, Gasparotti, Roberto, additional, Mardighian, Dikran, additional, Piano, Mariangela, additional, Cervo, Amedeo, additional, Eker, Omer Faruk, additional, Durous, Vincent, additional, Sourour, Nader-Antoine, additional, Elhorany, Mahmoud, additional, Zini, Andrea, additional, Simonetti, Luigi, additional, Marcheselli, Simona, additional, Paolo, Nuzzi Nunzio, additional, Houdart, Emmanuel, additional, Guédon, Alexis, additional, Ligot, Noémie, additional, Mine, Benjamin, additional, Consoli, Arturo, additional, Lapergue, Bertrand, additional, Cordona Portela, Pere, additional, Urra, Xabier, additional, Rodriguez, Alejandro, additional, Bolognini, Federico, additional, Lebedinsky, Pablo Ariel, additional, Pasco-Papon, Anne, additional, Godard, Sophie, additional, Marnat, Gaultier, additional, Sibon, Igor, additional, Limbucci, Nicola, additional, Nencini, Patrizia, additional, Nappini, Sergio, additional, Saia, Valentina, additional, Caldiera, Valentina, additional, Romano, Daniele, additional, Frauenfelder, Giulia, additional, Gallesio, Ivan, additional, Gola, Giuliano, additional, Menozzi, Roberto, additional, Genovese, Antonio, additional, Terrana, Alberto, additional, Giorgianni, Andrea, additional, Cappellari, Manuel, additional, Augelli, Raffaele, additional, Invernizzi, Paolo, additional, Pavia, Marco, additional, Lafe, Elvis, additional, Cavallini, Anna, additional, Giossi, Alessia, additional, Besana, Michele, additional, Valvassori, Luca, additional, Macera, Antonio, additional, Castellan, Lucio, additional, Salsano, Giancarlo, additional, Di Caterino, Fortunato, additional, Biondi, Alessandra, additional, Arquizan, Caroline, additional, Lebreuche, Julien, additional, Galvano, Gianluca, additional, Cannella, Alfio, additional, Cosottini, Mirco, additional, Lazzarotti, Guido, additional, Guizzardi, Giuseppe, additional, Stecco, Alessandro, additional, Tassi, Rossana, additional, Bracco, Sandra, additional, Bianchini, Elena, additional, Micieli, Camilla, additional, Pascarella, Rosario, additional, Napoli, Manuela, additional, Causin, Francesco, additional, Desal, Hubert, additional, Cotton, François, additional, Costalat, Vincent, additional, Delvoye, François, additional, Ciccio, Gabriele, additional, Smajda, Stanislas, additional, Redjem, Hocine, additional, Hébert, Solène, additional, Blanc, Raphaël, additional, Mazighi, Mikael, additional, Desilles, Jean-Philippes, additional, Mihoc, Dan, additional, Manisor, Monica, additional, Beaujeux, Rémy, additional, Quenardelle, Véronique, additional, Gheoca, Roxana, additional, Wolff, Valérie, additional, Pero, Guiglielmo, additional, Giuditta, Giussani, additional, Chiara, Ceresa, additional, Riva, Roberto, additional, Cappucci, Matteo, additional, Laubacher, Morgane, additional, Tuttle, Celia, additional, Piergallini, Lorenzo, additional, Turjman, Francis, additional, Clarençon, Frédéric, additional, Shotar, Eimad, additional, Lenck, Stéphanie, additional, Premat, Kevin, additional, Degos, Vincent, additional, Samson, Yves, additional, Rosso, Charlotte, additional, Alamowitch, Sonia, additional, Cirillo, Luigi, additional, Gentile, Mauro, additional, Migliaccio, Ludovica, additional, Isceri, Salvatore, additional, Rossi, Simone, additional, Baldini, Tommaso, additional, Dall’Olio, Massimo, additional, Cellerini, Martino, additional, Saint-Maurice, Jean-Pierre, additional, Civelli, Vittorio, additional, Fantoni, Matteo, additional, Gilles, Naeije, additional, Lise, Jodaïtis, additional, Boris, Lubicz, additional, Elens, Stephanie, additional, Thomas, Bonnet, additional, Adrien, Guenego, additional, Niloufar, Sadeghi, additional, Marc, Van Nuffelen, additional, Maria, Federico Di, additional, Coskun, Oguzhan, additional, Rodesch, Georges, additional, Zimatore, Sergio, additional, Florent, Gariel, additional, Berge, Jérôme, additional, Menegon, Patrice, additional, Barreau, Xavier, additional, Tourdias, Thomas, additional, Olindo, Stéphane, additional, Lucas, Ludovic, additional, Liegey, Jean-Sebastien, additional, Sagnier, Sharmila, additional, Renou, Pauline, additional, Couture, Marie, additional, Debruxelles, Sabrina, additional, Poli, Mathilde, additional, Musacchio, Mariano, additional, Delaitre, Mariette, additional, Padolecchia, Riccardo, additional, Ganci, Giuseppe, additional, Sugo, Annalisa, additional, Stefano, Barbero, additional, Giovanni, Taverna Giacomo, additional, Scoditti, Umberto, additional, Castellini, Paola, additional, Latte, Lilia, additional, Grisendi, Ilaria, additional, Epifani, Enrico, additional, Vizzari, Francesco, additional, Molinaro, Stefano, additional, Nativo, Luca, additional, Vinacci, Gabriele, additional, Bonetti, Bruno, additional, Micheletti, Nicola, additional, Tomelleri, Giampaolo, additional, Zampieri, Piergiuseppe, additional, Plebani, Mauro, additional, Grazioli, Andrea, additional, Ricciardi, Giuseppe Kenneth, additional, Polistena, Alessandra, additional, Alessando, Sgreccia, additional, Sanfilippo, Giuseppina, additional, Persico, Alessandra, additional, Boadu, William, additional, Cuzzoni, Maria Giovanna, additional, Magno, Serena, additional, Toscano, Gianpaolo, additional, Denaro, Maria Federica, additional, Tosi, Piera, additional, Censori, Bruno, additional, Puglisi, Valentina, additional, Vinciguerra, Luisa, additional, De Giuli, Valeria, additional, Mavillo, Nicola, additional, Renieri, Leonardo, additional, Fainardi, Enrico, additional, Vitale, Giovanni, additional, Panagiotis, Primikiris, additional, Charbonnier, Guillaume, additional, Claudio, Moratti, additional, Sallustio, Fabrizio, additional, Wlderk, Andrea, additional, Russo, Riccardo, additional, Bergui, Mauro, additional, Comelli, Chiara, additional, Boghi, Andrea, additional, Moynier, Marinette, additional, Maria Ciceri, Elisa Francesca, additional, Toni, Danilo, additional, Frandon, Julien, additional, Mourand, Isabelle, additional, Gaillard, Nicolas, additional, Mangiafico, Salvatore, additional, Derraz, Imad, additional, Dargazanli, Cyril, additional, Lefevre, Pierre-Henri, additional, Riquelme, Carlos, additional, Gascou, Gregory, additional, and Bonafe, Alain, additional more...
- Published
- 2021
- Full Text
- View/download PDF
50. Comparison of Woven EndoBridge device sizing with conventional measurements and virtual simulation using the Sim&Size software: a multicenter experience
- Author
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Cagnazzo, Federico, primary, Marnat, Gaultier, additional, Ferreira, Ivan, additional, Daube, Pierre, additional, Derraz, Imad, additional, Dargazanli, Cyril, additional, Lefevre, Pierre-Henri, additional, Gascou, Gregory, additional, Riquelme, Carlos, additional, Morganti, Riccardo, additional, Berge, Jérôme, additional, Gariel, Florent, additional, Barreau, Xavier, additional, and Costalat, Vincent, additional more...
- Published
- 2020
- Full Text
- View/download PDF
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