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39 results on '"Gargantini, G."'

1. Childbirth care among sars-cov-2 positive women in Italy

Author

Donati, S, Corsi, E, Salvatore, M, Maraschini, A, Bonassisa, S, Casucci, P, Cataneo, I, Cetin, I, D'Aloja, P, Dardanoni, G, De Ambrosi, E, Ferrazzi, E, Fieni, S, Franchi, M, Gargantini, G, Iurlaro, E, Leo, L, Liberati, M, Livio, S, Locci, M, Marozio, L, Martini, C, Maso, G, Mecacci, F, Meloni, A, Mignuoli, A, Patane, L, Pellegrini, E, Perotti, F, Perrone, E, Prefumo, F, Ramenghi, L, Rusciani, R, Savasi, V, Schettini, S, Simeone, D, Simeone, S, Spinillo, A, Steinkasserer, M, Tateo, S, Ternelli, G, Tironi, R, Trojano, V, Vergani, P, Zullino, S, Donati S., Corsi E., Salvatore M. A., Maraschini A., Bonassisa S., Casucci P., Cataneo I., Cetin I., D'aloja P., Dardanoni G., De Ambrosi E., Ferrazzi E., Fieni S., Franchi M. P., Gargantini G., Iurlaro E., Leo L., Liberati M., Livio S., Locci M., Marozio L., Martini C., Maso G., Mecacci F., Meloni A., Mignuoli A. D., Patane L., Pellegrini E., Perotti F., Perrone E., Prefumo F., Ramenghi L., Rusciani R., Savasi V., Schettini S. C. A., Simeone D., Simeone S., Spinillo A., Steinkasserer M., Tateo S., Ternelli G., Tironi R., Trojano V., Vergani P., Zullino S., Donati, S, Corsi, E, Salvatore, M, Maraschini, A, Bonassisa, S, Casucci, P, Cataneo, I, Cetin, I, D'Aloja, P, Dardanoni, G, De Ambrosi, E, Ferrazzi, E, Fieni, S, Franchi, M, Gargantini, G, Iurlaro, E, Leo, L, Liberati, M, Livio, S, Locci, M, Marozio, L, Martini, C, Maso, G, Mecacci, F, Meloni, A, Mignuoli, A, Patane, L, Pellegrini, E, Perotti, F, Perrone, E, Prefumo, F, Ramenghi, L, Rusciani, R, Savasi, V, Schettini, S, Simeone, D, Simeone, S, Spinillo, A, Steinkasserer, M, Tateo, S, Ternelli, G, Tironi, R, Trojano, V, Vergani, P, Zullino, S, Donati S., Corsi E., Salvatore M. A., Maraschini A., Bonassisa S., Casucci P., Cataneo I., Cetin I., D'aloja P., Dardanoni G., De Ambrosi E., Ferrazzi E., Fieni S., Franchi M. P., Gargantini G., Iurlaro E., Leo L., Liberati M., Livio S., Locci M., Marozio L., Martini C., Maso G., Mecacci F., Meloni A., Mignuoli A. D., Patane L., Pellegrini E., Perotti F., Perrone E., Prefumo F., Ramenghi L., Rusciani R., Savasi V., Schettini S. C. A., Simeone D., Simeone S., Spinillo A., Steinkasserer M., Tateo S., Ternelli G., Tironi R., Trojano V., Vergani P., and Zullino S.

Abstract

The new coronavirus emergency spread to Italy when little was known about the infection’s impact on mothers and newborns. This study aims to describe the extent to which clinical practice has protected childbirth physiology and preserved the mother–child bond during the first wave of the pandemic in Italy. A national population-based prospective cohort study was performed enrolling women with confirmed SARS-CoV-2 infection admitted for childbirth to any Italian hospital from 25 February to 31 July 2020. All cases were prospectively notified, and information on peripartum care (mother–newborn separation, skin-to-skin contact, breastfeeding, and rooming-in) and maternal and perinatal outcomes were collected in a structured form and entered in a web-based secure system. The paper describes a cohort of 525 SARS-CoV-2 positive women who gave birth. At hospital admission, 44.8% of the cohort was asymptomatic. At delivery, 51.9% of the mothers had a birth support person in the delivery room; the average caesarean section rate of 33.7% remained stable compared to the national figure. On average, 39.0% of mothers were separated from their newborns at birth, 26.6% practised skin-to-skin, 72.1% roomed in with their babies, and 79.6% of the infants received their mother’s milk. The infants separated and not separated from their SARS-CoV-2 positive mothers both had good outcomes. At the beginning of the pandemic, childbirth raised awareness and concern due to limited available evidence and led to “better safe than sorry” care choices. An improvement of the peripartum care indicators was observed over time.

Published
2021

2. Il progetto BLUES: implementare pratiche innovative nelle attività di screening e di home visiting rivolte alle donne con depressione perinatale

Author

Lora, A, Andreoni, G, Barri, M, Frisone, E, Fumagalli, S, Gargantini, G, Leogrande, M, Magliano, L, MONZIO COMPAGNONI, M, Nespoli, A, Pellegrini, E, Perego, P, Rovelli, N, Sacchi, P, Scuratti, L, Zanini, R, Antonio Lora, Giuseppe Andreoni, Miriam Barri, Enrico Frisone, Simona Fumagalli, Gianluigi Gargantini, Melania Leogrande, Lorenza Magliano, Matteo MONZIO COMPAGNONI, Antonella Nespoli, Edda Pellegrini, Paolo Perego, Nadia Rovelli, Paola Sacchi, Luisa Scuratti, Rinaldo Zanini, Lora, A, Andreoni, G, Barri, M, Frisone, E, Fumagalli, S, Gargantini, G, Leogrande, M, Magliano, L, MONZIO COMPAGNONI, M, Nespoli, A, Pellegrini, E, Perego, P, Rovelli, N, Sacchi, P, Scuratti, L, Zanini, R, Antonio Lora, Giuseppe Andreoni, Miriam Barri, Enrico Frisone, Simona Fumagalli, Gianluigi Gargantini, Melania Leogrande, Lorenza Magliano, Matteo MONZIO COMPAGNONI, Antonella Nespoli, Edda Pellegrini, Paolo Perego, Nadia Rovelli, Paola Sacchi, Luisa Scuratti, and Rinaldo Zanini

Abstract

Introduction Perinatal depression is frequent (1 woman out of 10 during the perinatal period), nonetheless to this day the screening is incomplete and the treatment gap is high. Materials and methods The BLUES project was financed by the Italian Ministry of Health and implemented in 10 Local Health Units of Lombardy Region. It had the goals of improving screening and implementing home visiting for women with perinatal depression. As far as the first goal, a smartphone app searchable by authorized professionals has been developed for transmitting screening tools (Edinburgh Postnatal Depression Scale - EPDS - and Whooley questions) to a cloud database; the app was also connected to a free website informing on mental health during the perinatal period. As far as the second goal, a home visiting programme was implemented according to the WHO Thinking Healthy method. A total of 110 professionals (most midwives), working in the family care centers, attended a structured training course in the Thinking Healthy approach and then applied the intervention to women during the perinatal period. The effectiveness and feasibility of the intervention were assessed at its completion (pre-post comparisons). Results The smartphone app and the related website were successfully activated in family care centers in the Province of Lecco (Lombardy, Italy). 39 women responding to selection criteria (EPDS 10 and a diagnosis of depression) were recruited for the home visiting intervention: 31 of them have completed the Thinking Healthy program. A clinically significant reduction of the EPDS scores was assessed in 80% of the women with moderate depressive symptoms (EPDS score ≥ 12). Both women and professionals evaluated the intervention useful and acceptable. Conclusions The BLUES project improved the screening using e-tools and implemented home visiting following the Thinking Healthy method. The process of task shifting from mental health sector to midwives was successful, while professiona

Published
2022

5. COVID-19 Obstetrics Task Force, Lombardy, Italy: Executive management summary and short report of outcome

Author

Ferrazzi, E, Frigerio, L, Cetin, I, Vergani, P, Spinillo, A, Prefumo, F, Pellegrini, E, Gargantini, G, Ferrazzi, Enrico M, Frigerio, Luigi, Cetin, Irene, Vergani, Patrizia, Spinillo, Arsenio, Prefumo, Federico, Pellegrini, Edda, Gargantini, Gianluigi, Ferrazzi, E, Frigerio, L, Cetin, I, Vergani, P, Spinillo, A, Prefumo, F, Pellegrini, E, Gargantini, G, Ferrazzi, Enrico M, Frigerio, Luigi, Cetin, Irene, Vergani, Patrizia, Spinillo, Arsenio, Prefumo, Federico, Pellegrini, Edda, and Gargantini, Gianluigi

Abstract

From February 24, 2020, a COVID-19 obstetric task force was structured to deliver management recommendations for obstetric care. From March 1, 2020, six COVID-19 hubs and their spokes were designated. An interim analysis of cases occurring in or transferred to these hubs was performed on March 20, 2020 and recommendations were released on March 24, 2020. The vision of this strict organization was to centralize patients in high-risk maternity centers in order to concentrate human resources and personal protective equipment (PPE), dedicate protected areas of these major hospitals, and centralize clinical multidisciplinary experience with this disease. All maternity hospitals were informed to provide a protected labor and delivery room for nontransferable patients in advanced labor. A pre-triage based on temperature and 14 other items was developed in order to screen suspected patients in all hospitals to be tested with nasopharyngeal swabs. Obstetric outpatient facilities were instructed to maintain scheduled pregnancy screening as per Italian guidelines, and to provide pre-triage screening and surgical masks for personnel and patients for pre-triage-negative patients. Forty-two cases were recorded in the first 20 days of hub and spoke organization. The clinical presentation was interstitial pneumonia in 20 women. Of these, seven required respiratory support and eventually recovered. Two premature labors occurred.

Published
2020

6. Strategies for preventing group B streptococcal infections in newborns: A nation-wide survey of Italian policies

Author

Tzialla, C, berardi, A, farina, C, clerici, P, borghesi, A, viora, E, scollo, P, stronati, M, Task Force for group B streptococcal infections for the Italian Society of Neonatology including Stival, G, barbaglia, Ma, guala, A, giunta, E, parola, L, grossignani, Mr, perri, P, tubaldi, L, alletto, G, daidone, S, flacco, V, dani, C, sterpa, A, rapisardi, G, elicio, Mr, faldella, G, capretti, Mg, messner, H, bandiera, M, achille, C, azzali, A, montrasio, G, mariani, S, galvagno, G, giacosa, E, de Angelis, F, spandrio, M, serra, A, garofalo, F, perona, A, porcelli, F, ferrero, F, De Franco, S, paollilo, P, picone, S, besana, R, varisco, T, farina, M, memo, L, nicolini, G, lietti, D, Di Chiara, G, rottoli, A, Bonabitacola, T, Cortis, E, Neri, E, Martinelli, S, Ilardi, L, Rondanini, Gf, Calzi, P, Gatta, A, Quntadamo, Pa, Ivaldi, M, Terenzani, L, Di Lascio, N, Travaglio, Md, Vetrano, G, Furcolo, G, Vitacco, V, Intini, C, Frigerio, M, Stroppiana, P, Policicchio, G, Mesirca, P, Gianino, P, Audenio, E, Paludetto, R, Raimondi, F, Pugliese, A, Valentino, L, Nosari, N, Marchesano, G, Chirico, G, Bellù, R, Menchini, M, Poletti, A, E T, Vacchiano, Pinto, L, E D, Perri, Coppola, R, Perini, R, Vetrella, A, De Luca, G, Lista, G, Cavigioli, F, Bettinelli, A, Massironi, E, Franco, C, Bernardo, L, Poli, S, Palladini, M, Tota, V, Spadavecchia, F, Zuccotti, Gv, Pogliani, L, Bracaglia, G, Mancini, Al, Zocco, F, Iozzia, G, Auriemma, A, Teani, M, Mangilli, G, Tempra, Am, Di Terlizi, L, Bottino, R, Salvi, C, Fortunato, V, Musaico, R, Gargantini, G, Carrera, G, Magaldi, R, Taurino, L, D'Onofrio, Am, Buffone, E, Tempera, A, Agosti, M, Garzia, P, Mosca, F, Pugni, L, Tagliabue, P, Colombo, C, Demi, M, Picco, G, Carlucci, A, Zorzi, G, Padula, D, Cardone, Ml, Buonocore, G, Muraca, Mc, Boldrini, A, Ciantelli, M, Lanari, M, Serra, L, Felici, L, Banderalli, G, Brambilla, C, Dall'Agnola, A, Viviani, E, Zonca, Mc, Licardi, G, Chiara, A, Ancora, G, Papa, I, Gancia, P, Pomero, G, Deloglu, A, Villani, P, Mussini, P, Canidio, E, Migliavacca, D, Di Fabio, S, Cipollone, I, Biasucci, G, Rubbi, P, Piepoli, M, Guastaferro, N, Infriccioli, F, Bertino, E, Perathoner, C, Parmigiani, S, Suriano, G, Ianniello, C, Biasini, A, Azzalli, M, Timpani, G, Barresi, S, Caoci, G, Ciccotti, R, De Curtis, M, Natale, F, Finocchi, M, Haass, C, Milillo, F, Lucieri, S, Guercio, E, Canepa, Sa, Scozia, G, Antonucci, R, Limongelli, O, Macciò, S, Mongelli, F, Colonna, F, Dragovic, D, Calipa, Mt, Cohen, A, Moresco, L, Italian Society of Obstetricians and Gynecologists including La Spina, R, Ruggeri, R, Luehwink, A, Brattoli, M, Fedi, A, Lacchi, L, Ettore, G, Pappalardo, E, Conoscenti, G, Zeni, B, Spellecchia, D, Favretti, L, Spagna, L, Zaglio, S, Bresciani, D, Bandini, A, Mancini, R, Mustoni, P, Dodero, D, Grimaldi, M, Di Mario, M, Migliorini, P, Kemeny, A, Anastasio, Ps, Riccardi, T, Maggino, T, Cerri, G, Puggina, P, Marconi, Am, Morgia, S, Bellia, G, D'Anna, Mr, Catania, M, Bacchi Modena, A, Franchi, L, Calonaci, N, Schettini, S, Paradiso, R, Saccucci, P, Ioppi, M, Zorzi, M, Stellin, G, Patacchiola, F, Carrata, L, Bassini, D, San Marco, L, Todros, T, Tibadi, C, Liborio, M, Italian Association of Clinical Microbiologists including Laricchia, R, Tauro, L, Ferrara, F, Nuara, C, Ghiraldi, E, Molinari, F, Comessatti, A, Rocchetti, A, Di Matteo, L, Miconi, V, Calvi, P, Pernigotti, A, Fabozzi, F, Micca, G, Monticone, G, Sarti, M, Da Rin, G, Zoppelletto, M, Modolo, E, Landini, Mp, Furlini, G, Galluppi, E, Pagani, E, Aschbacher, R, Innocenti, P, Bresolin, N, Raggi, Me, Bonfanti, C, De Francesco, M, Santer, P, Griessmaier, A, De Francesco, D, Pirali, A, Prasciolu, C, Usai, F, Cuzzone, G, Scutellà, M, Tramacere, P, Fossati, D, Piaserico, G, Bordignon, G, Sciacca, A, Di Vincenzo, F, Imbriani, A, Melotti, D, Catanoso, G, Rivetti, I, Neri, G, Bruno, R, Bacelle, L, Sartore, P, Giana, G, Sala, E, Giraldi, C, Cavalcanti, P, Perugini, M, Perugini, A, Ginardi, C, Maritano, D, Ferrini, A, Bonettini, A, Avanzini, A, Gasperoni, S, Pieretti, B, Montanari, E, Carillo, C, Rossi, Mr, Laureti, A, Baldoni, Ml, Serra, D, Melioli, G, Bandettini, R, Oneto, F, Colla, R, Storchi Incerti, S, Lanzini, F, Pauri, P, Tili, E, Leone, Ra, Verdastro, G, Megha, M, Luzzaro, F, Conti, A, Busulini, L, Mirri, P, Diodati, R, Vettori, C, Pittalis, S, Anesi, A, Fiore, A, Goglia, L, Vitullo, E, Sinno, A, Platzgummer, S, Spitaler, C, Trabucchi, Mc, Besozzi, M, Cesana, E, Inghilleri, G, Grosso, S, D'Angelo, R, Fogato, E, Lavarda, F, Ortisi, G, Clementi, M, Cichero, P, Rumpianesi, F, Venturelli, C, Mortillaro, F, Daffara, S, Catania, Mr, Iula, D, Andreoni, S, Politi, A, Agostinelli, C, Paparella, C, Capozzi, D, Notaris, P, Bistoni, F, Mencacci, A, Valentini, M, Filippetti, A, Confalonieri, M, Novarese, O, Bonini, F, Salamone, D, Camporese, A, De Rosa, R, Casprini, P, Degl'Innocenti, R, Giordano, R, Allù, Mt, Zanella, D, Malandrino, M, Tronci, M, Valmarin, M, Leonetti, G, Falco, S, Meledandri, M, Ballardini, M, Spanò, A, Cava, Mc, Mascellino, Mt, Schinella, M, Gualdi, P, Casari, E, Scattolo, N, Motta, C, Perfetti, C, Bassano, M, Cera, G, Iafisco, P, Mura, I, Palmieri, A, Migliardi, M, Ferlini, M, Grandi, G, Giardini, F, Albano, F, Latino, M, Ferrero, Mp, Bellizia, L, Russolo, M, Russolo, S, Pesenti, A, Fasano, Ma, Previato, S, Radillo, O, Busetti, M, Ferrari, P, Siderini, V, Puzzolante, L, Scarparo, C, Arzese, A, Cappuccia, N, Lodolo, L, Delledonne, L, Gramoni, A, Maiolo, V, Gheller, A, Spadaro, S, Balzaretti, M, Tzialla, C., Berardi, A., Farina, C., Clerici, P., Borghesi, A., Viora, E., Scollo, P., Stronati, M., Stival, G., Barbaglia, M. A., Guala, A., Giunta, E., Parola, L., Grossignani, M. R., Perri, P., Tubaldi, L., Alletto, G., Daidone, S., Flacco, V., Dani, C., Sterpa, A., Rapisardi, G., Elicio, M. R., Faldella, G., Capretti, M. G., Messner, H., Bandiera, M., Achille, C., Azzali, A., Montrasio, G., Mariani, S., Galvagno, G., Giacosa, E., de Angelis, F., Spandrio, M., Serra, A., Garofalo, F., Perona, A., Porcelli, F., Ferrero, F., De Franco, S., Paollilo, P., Picone, S., Besana, R., Varisco, T., Farina, M., Memo, L., Nicolini, G., Lietti, D., Di Chiara, G., Rottoli, A., Bonabitacola, T., Cortis, E., Neri, E., Martinelli, S., Ilardi, L., Rondanini, G. F., Calzi, P., Gatta, A., Quntadamo, P. A., Ivaldi, M., Terenzani, L., Di Lascio, N., Travaglio, M. D., Vetrano, G., Furcolo, G., Vitacco, V., Intini, C., Frigerio, M., Stroppiana, P., Policicchio, G., Mesirca, P., Gianino, P., Audenio, E., Paludetto, R., Raimondi, F., Pugliese, A., Valentino, L., Nosari, N., Marchesano, G., Chirico, G., Bell(`u), R., Menchini, M., Poletti, A., Vacchiano, T., Pinto, L., Perri, D., Coppola, R., Perini, R., Vetrella, A., De Luca, G., Lista, G., Cavigioli, F., Bettinelli, A., Massironi, E., Franco, C., Bernardo, L., Poli, S., Palladini, M., Tota, V., Spadavecchia, F., Zuccotti, G. V., Pogliani, L., Bracaglia, G., Mancini, A. L., Zocco, F., Iozzia, G., Auriemma, A., Teani, M., Mangilli, G., Tempra, A. M., Di Terlizi, L., Bottino, R., Salvi, C., Fortunato, V., Musaico, R., Gargantini, G., Carrera, G., Magaldi, R., Taurino, L., D?onofrio, A. M., Buffone, E., Tempera, A., Agosti, M., Garzia, P., Mosca, F., Pugni, L., Tagliabue, P., Colombo, C., Demi, M., Picco, G., Carlucci, A., Zorzi, G., Padula, D., Cardone, M. L., Buonocore, G., Muraca, M. C., Boldrini, A., Ciantelli, M., Lanari, M., Serra, L., Felici, L., Banderalli, G., Brambilla, C., Dall?agnola, A., Viviani, E., Zonca, M. C., Licardi, G., Chiara, A., Ancora, G., Papa, I., Gancia, P., Pomero, G., Deloglu, A., Villani, P., Mussini, P., Canidio, E., Migliavacca, D., Di Fabio, S., Cipollone, I., Biasucci, G., Rubbi, P., Piepoli, M., Guastaferro, N., Infriccioli, F., Bertino, E., Perathoner, C., Parmigiani, S., Suriano, G., Ianniello, C., Biasini, A., Azzalli, M., Timpani, G., Barresi, S., Caoci, G., Ciccotti, R., De Curtis, M., Natale, F., Finocchi, M., Haass, C., Milillo, F., Lucieri, S., Guercio, E., Canepa, S. A., Scozia, G., Antonucci, R., Limongelli, O., Macci(`o), S., Mongelli, F., Colonna, F., Dragovic, D., Calipa, M. T., Cohen, A., Moresco, L., La Spina, R., Ruggeri, R., Luehwink, A., Brattoli, M., Fedi, A., Lacchi, L., Ettore, G., Pappalardo, E., Conoscenti, G., Zeni, B., Spellecchia, D., Favretti, L., Spagna, L., Zaglio, S., Bresciani, D., Bandini, A., Mancini, R., Mustoni, P., Dodero, D., Grimaldi, M., Di Mario, M., Migliorini, P., Kemeny, A., Anastasio, P. S., Riccardi, T., Maggino, T., Cerri, G., Puggina, P., Marconi, A. M., Morgia, S., Bellia, G., D?anna, M. R., Catania, M., Bacchi Modena, A., Franchi, L., Calonaci, N., Schettini, S., Paradiso, R., Saccucci, P., Ioppi, M., Zorzi, M., Stellin, G., Patacchiola, F., Carrata, L., Bassini, D., San Marco, L., Todros, T., Tibadi, C., Liborio, M., Laricchia, R., Tauro, L., Ferrara, F., Nuara, C., Ghiraldi, E., Molinari, F., Comessatti, A., Rocchetti, A., Di Matteo, L., Miconi, V., Calvi, P., Pernigotti, A., Fabozzi, F., Micca, G., Monticone, G., Sarti, M., Da Rin, G., Zoppelletto, M., Modolo, E., Landini, M. P., Furlini, G., Galluppi, E., Pagani, E., Aschbacher, R., Innocenti, P., Bresolin, N., Raggi, M. E., Bonfanti, C., De Francesco, M., Santer, P., Griessmaier, A., De Francesco, D., Pirali, A., Prasciolu, C., Usai, F., Cuzzone, G., Scutell(`a), M., Tramacere, P., Fossati, D., Piaserico, G., Bordignon, G., Sciacca, A., Di Vincenzo, F., Imbriani, A., Melotti, D., Catanoso, G., Rivetti, I., Neri, G., Bruno, R., Bacelle, L., Sartore, P., Giana, G., Sala, E., Giraldi, C., Cavalcanti, P., Perugini, M., Perugini, A., Ginardi, C., Maritano, D., Ferrini, A., Bonettini, A., Avanzini, A., Gasperoni, S., Pieretti, B., Montanari, E., Carillo, C., Rossi, M. R., Laureti, A., Baldoni, M. L., Serra, D., Melioli, G., Bandettini, R., Oneto, F., Colla, R., Storchi Incerti, S., Lanzini, F., Pauri, P., Tili, E., Leone, R. A., Verdastro, G., Megha, M., Luzzaro, F., Conti, A., Busulini, L., Mirri, P., Diodati, R., Vettori, C., Pittalis, S., Anesi, A., Fiore, A., Goglia, L., Vitullo, E., Sinno, A., Platzgummer, S., Spitaler, C., Trabucchi, M. C., Besozzi, M., Cesana, E., Inghilleri, G., Grosso, S., D?angelo, R., Fogato, E., Lavarda, F., Ortisi, G., Clementi, M., Cichero, P., Rumpianesi, F., Venturelli, C., Mortillaro, F., Daffara, S., Catania, M. R., Iula, D., Andreoni, S., Politi, A., Agostinelli, C., Paparella, C., Capozzi, D., Notaris, P., Bistoni, F., Mencacci, A., Valentini, M., Filippetti, A., Confalonieri, M., Novarese, O., Bonini, F., Salamone, D., Camporese, A., De Rosa, R., Casprini, P., Degl?innocenti, R., Giordano, R., All(`u), M. T., Zanella, D., Malandrino, M., Tronci, M., Valmarin, M., Leonetti, G., Falco, S., Meledandri, M., Ballardini, M., Span(`o), A., Cava, M. C., Mascellino, M. T., Schinella, M., Gualdi, P., Casari, E., Scattolo, N., Motta, C., Perfetti, C., Bassano, M., Cera, G., Iafisco, P., Mura, I., Palmieri, A., Migliardi, M., Ferlini, M., Grandi, G., Giardini, F., Albano, F., Latino, M., Ferrero, M. P., Bellizia, L., Russolo, M., Russolo, S., Pesenti, A., Fasano, M. A., Previato, S., Radillo, O., Busetti, M., Ferrari, P., Siderini, V., Puzzolante, L., Scarparo, C., Arzese, A., Cappuccia, N., Lodolo, L., Delledonne, L., Gramoni, A., Maiolo, V., Gheller, A., Spadaro, S., Balzaretti, M., Tzialla, Chryssoula, Berardi, Alberto, Farina, Claudio, Clerici, Pierangelo, Borghesi, Alessandro, Viora, Elsa, Scollo, Paolo, Stronati, Mauro, [.., Lanari, Marcello, Faldella, Giacomo, and ]

Subjects
Male, Pediatrics, Group B, 0302 clinical medicine, Neonate, Pregnancy, Surveys and Questionnaires, Prevalence, Mass Screening, Blood culture, 030212 general & internal medicine, Antibiotic prophylaxis, Survey, GBS, Group B streptococcus, Infection, Newborn infant, Adult, Antibiotic Prophylaxis, Female, Health Surveys, Humans, Infant, Newborn, Italy, Neonatal Screening, Pregnancy Complications, Infectious, Prenatal Care, Primary Prevention, Risk Assessment, Streptococcal Infections, Streptococcus agalactiae, reproductive and urinary physiology, Group B streptococcu, medicine.diagnostic_test, lcsh:RJ1-570, Infectious, Perinatology and Child Health, Pediatrics, Perinatology and Child Health, medicine.medical_specialty, Antibiotic sensitivity, Group B Streptococcal Infection, Prenatal care, 03 medical and health sciences, 030225 pediatrics, medicine, Intensive care medicine, Mass screening, business.industry, Public health, Infant, lcsh:Pediatrics, Newborn, Pregnancy Complications, business
Abstract

Background There are no Italian data regarding the strategies for preventing neonatal group B streptococcal (GBS) infection. We conducted a national survey in order to explore obstetrical, neonatal and microbiological practices for the GBS prevention. Methods Three distinct questionnaires were sent to obstetricians, neonatologists and microbiologists. Questionnaires included data on prenatal GBS screening, maternal risk factors, intrapartum antibiotic prophylaxis, microbiological information concerning specimen processing and GBS antimicrobial susceptibility. Results All respondent obstetrical units used the culture-based screening approach to identify women who should receive intrapartum antibiotic prophylaxis, and more than half of the microbiological laboratories (58%) reported using specimen processing consistent with CDC guidelines. Most neonatal units (89 out of 107, 82%) reported using protocols for preventing GBS early-onset sepsis consistent with CDC guidelines. Conclusions The screening-based strategy is largely prevalent in Italy, and most protocols for preventing GBS early-onset sepsis are consistent with CDC guidelines. However, we found discrepancies in practices among centers that may reflect the lack of Italian guidelines issued by public health organizations.

Published
2017

7. Management of the mother-infant dyad with suspected or confirmed SARS-CoV-2 infection in a highly epidemic context.

Author

Pietrasanta, C., Pugni, L., Ronchi, A., Schena, F., Davanzo, R., Gargantini, G., Ferrazzi, E., and Mosca, F.

Subjects
SARS-CoV-2, COVID-19, HOSPITAL maternity services, DYADS, INFECTION
Abstract

In the context of SARS-CoV-2 pandemic, the hospital management of mother-infant pairs poses to obstetricians and neonatologists previously unmet challenges. In Lombardy, Northern Italy, 59 maternity wards networked to organise the medical assistance of mothers and neonates with suspected or confirmed SARS-CoV-2 infection. Six "COVID-19 maternity centres" were identified, the architecture and activity of obstetric and neonatal wards of each centre was reorganised, and common assistance protocols for the management of suspected and proven cases were formulated. Here, we present the key features of this reorganization effort, and our current management of the mother-infant dyad before and after birth, including our approach to rooming-in practice, breastfeeding and neonatal follow-up, based on the currently available scientific evidence. Considered the rapid diffusion of COVID-19 all over the world, we believe that preparedness is fundamental to assist mother-infant dyads, minimising the risk of propagation of the infection through maternity and neonatal wards. [ABSTRACT FROM AUTHOR]

Published
2020
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9. Adherence to guidelines for management of children hospitalized for acute diarrhea

Author

Lo Vecchio, A, Liguoro, I, Bruzzese, D, Scotto, R, Parola, L, Gargantini, G, Guarino, A, Accreditation, Quality Improvement Working Group of Italian Society of Pediatrics Kosova, P, Di Benedetto, L, Gattinara, Gc, Cursi, L, Parmigiani, S, Maddaluno, S, Campa, A, Caroccia, C, Adamoli, P, Forchì, G, Di Bari, C, Daniele, Rm, Saitta, F, Di Fraia, T, Bellettato, M, Meneghini, A, Principi, N, Esposito, S, Borgna, C, Fiumana, E, Zanconato, S, Masiero, S, Paravati, F, Pacenza, C, Cherubini, S, Frasca, D, Siani, P, De Brasi, D, Montrasio, G, Parolo, E, Podestà, Af, Tonella, M, Longhi, R, Ortisi, Mt, Rondanini, G, Calzi, P, Zucchinetti, P, Insolvibile, A, Navone, C, Ventura, F, Parisi, G, Isolato, V, Martemucci, L, D'Avino, P, Vetrano, G, Limongelli, Mg, Icilio, D, Muccioli, R., COLELLA, Maria Grazia, PACE, Maria Caterina, PERRONE, Laura, CAPRISTO, Carlo, Lo Vecchio, A, Liguoro, I, Bruzzese, D, Scotto, R, Parola, L, Gargantini, G, Guarino, A, Accreditation, Quality Improvement Working Group of Italian Society of Pediatrics Kosova, P, Di Benedetto, L, Gattinara, Gc, Cursi, L, Parmigiani, S, Maddaluno, S, Campa, A, Caroccia, C, Adamoli, P, Forchì, G, Di Bari, C, Daniele, Rm, Saitta, F, Di Fraia, T, Bellettato, M, Meneghini, A, Principi, N, Esposito, S, Borgna, C, Fiumana, E, Zanconato, S, Masiero, S, Paravati, F, Pacenza, C, Colella, Maria Grazia, Cherubini, S, Frasca, D, Siani, P, De Brasi, D, Montrasio, G, Parolo, E, Podestà, Af, Tonella, M, Longhi, R, Ortisi, Mt, Rondanini, G, Calzi, P, Zucchinetti, P, Insolvibile, A, Navone, C, Ventura, F, Parisi, G, Isolato, V, Pace, Maria Caterina, Martemucci, L, D'Avino, P, Vetrano, G, Limongelli, Mg, Perrone, Laura, Capristo, Carlo, Icilio, D, Muccioli, R., LO VECCHIO, Andrea, Bruzzese, Dario, and Guarino, Alfredo

Subjects
Diarrhea, Male, Microbiological Techniques, Microbiology (medical), Acute diarrhea, medicine.medical_specialty, Psychological intervention, Guidelines, Health Services Misuse, Hospital, Internal medicine, medicine, Humans, Prospective Studies, Medical prescription, Child, Preschool, Antidiarrheals, Prospective cohort study, book, Pediatric gastroenterology, Adherence, Gastroenteritis, Acute Disease, Anti-Bacterial Agents, Child, Preschool, Feeding Behavior, Female, Guideline Adherence, Hospitalization, Infant, Italy, Practice Guidelines as Topic, Probiotics, business.industry, Hepatology, Antidiarrheal Drugs, Infectious Diseases, Pediatrics, Perinatology and Child Health, Emergency medicine, Pediatric Infectious Disease, book.journal, business
Abstract

BACKGROUND: The major burden of acute gastroenteritis (AGE) in childhood is related to its high frequency and the large number of hospitalizations, medical consultations, tests and drug prescriptions. The adherence to evidence-based recommendations for AGE management in European countries is unknown. The purpose of the study was to compare hospital medical interventions for children admitted for AGE with recommendations reported in the European Societies of Pediatric Gastroenterology, Hepatology and Nutrition and Pediatric Infectious Diseases guidelines. METHODS: A multicenter prospective study was conducted in 31 Italian hospitals. Data on children were collected through an online clinical reporting form and compared with European Societies of Pediatric Gastroenterology, Hepatology and Nutrition and Pediatric Infectious Diseases guidelines for AGE. The main outcomes were the inappropriate hospital admissions and the percentage of compliance to the guidelines (full >90%, partial >80% compliance) based on the number and type of violations to evidence-based recommendations. RESULTS: Six-hundred and twelve children (53.6% male, mean age 22.8 ± 15.4 months) hospitalized for AGE were enrolled. Many hospital admissions (346/602, 57.5%) were inappropriate. Once admitted, 20.6% (126/612) of children were managed in full compliance with the guidelines and 44.7% (274/612) were managed in partial compliance. The most common violations were requests for microbiologic tests (404; 35.8%), diet changes (310; 27.6%) and the prescription of non-recommended probiotics (161; 14.2%), antibiotics (103; 9.2%) and antidiarrheal drugs (7; 0.6%). CONCLUSIONS: Inappropriate hospital admissions and medical interventions are still common in the management of children with AGE in Italy. Implementation of guidelines recommendations is needed to improve quality of care

Published
2014

13. La prevenzione dietetica primaria nel neonato nei punti-nascita di milano E provincia

Author

Testo, E. D., Fiocchi, A., Qualizza, R., Onorato, J., Agostoni, C., Altobelli, R., Andreoli, A., Motta, G., Ortolani, C., Ottolenghi, A., Pastori, P., Varin, E., Vitaliti, A., Savarino, A., Marini, A., Bianchi, C., D Arcais, A. F., Tornaghi, R., Stival, G., Console, V., Perego, O., Acquistapace, F., Leo, G., FABIO MOSCA, Moro, G., Lovati, C., Corbella, E., Pietro, C. D., Dotti, G., Calzi, P., Chiappa, M., Formantici, F., Rondanini, G., Flauto, U., Russo, F., Marazzini, P., Merli, B., Ribaud, O., Ricciardi, G., Bonvini, G., Galeone, M., Gardoni, L., Giranzani, F., Vargas, O. P., Vaccari, A., Ribaldi, M., Perletti, L., Gargantini, G., Predabissi, O., Melegnano, Magni, L. A., Colnaghi, C., Turati, L., Besana, R., and Placa, G. L.

14. The Registry for Insulin-Dependent Diabetes Mellitus in Italy (RIDI) project | Il progetto per il registro italiano del Diabete Mellito insulino-dipendente (RIDI)

Author

Cherubini, V., Carle, F., Iannilli, A., Kantar, A., Coppa, G. V., Chiumello, G., Angius, E., Banin, P., Bellù, L., Berardi, R., Bernasconi, S., Mariani, S., Boscherini, B., Fonte, M. T., Cacciari, E., Salardi, S., Cadario, F., Calisti, Cardella, F., Cavallo, L., Cerasoli, G., Cerutti, F., Chiarelli, F., Verrotti, A., Cicchetti, M., Cotellessa, M., Picco, P., Crino, A., Dammacco, F., Giorgi, G., Luca, F., Falorni, A., Fifi, A., Franzese, A., Gargantini, G., Giorgetti, R., Guazzarotti, L., La Loggia, A., Lorini, R., D Annunzio, G., Lucentini, L., Mannazzu, M. C., Marietti, G., Marsciani, A., Martinucci, M., Mastrangelo, C., Meossi, C., Meschi, F., Monciotti, C., Multari, G., Pinelli, L., Pocecco, M., Prisco, F., Jafusco, D., Reitano, G., Sacchini, P., Sacco, M., Alessandro Salvatoni, Scaramuzza, A., Vanelli, M., Chiari, G., Vanini, R., Visentin, A., and Zanini, R.

15. The Registry for Insulin-Dependent Diabetes Mellitus in Italy (RIDI) project,Il progetto per il registro italiano del Diabete Mellito insulino-dipendente (RIDI)

Author

Cherubini, V., Carle, F., Iannilli, A., Kantar, A., Coppa, G. V., Chiumello, G., Angius, E., Banin, P., Bellù, L., Berardi, R., Bernasconi, S., Mariani, S., Boscherini, B., Fonte, M. T., Cacciari, E., Salardi, S., Cadario, F., Calisti, francesca cardella, Cavallo, L., Cerasoli, G., Cerutti, F., Chiarelli, F., Verrotti, A., Cicchetti, M., Cotellessa, M., Picco, P., Crino, A., Dammacco, F., Giorgi, G., Luca, F., Falorni, A., Fifi, A., Franzese, A., Gargantini, G., Giorgetti, R., Guazzarotti, L., La Loggia, A., Lorini, R., D Annunzio, G., Lucentini, L., Mannazzu, M. C., Marietti, G., Marsciani, A., Martinucci, M., Mastrangelo, C., Meossi, C., Meschi, F., Monciotti, C., Multari, G., Pinelli, L., Pocecco, M., Prisco, F., Jafusco, D., Reitano, G., Sacchini, P., Sacco, M., Salvatoni, A., Scaramuzza, A., Vanelli, M., Chiari, G., Vanini, R., Visentin, A., and Zanini, R.

17. Il progetto BLUES: implementare pratiche innovative nelle attività di screening e di home visiting rivolte alle donne con depressione perinatale

Author

Antonio Lora, Giuseppe Andreoni, Miriam Barri, Enrico Frisone, Simona Fumagalli, Gianluigi Gargantini, Melania Leogrande, Lorenza Magliano, Matteo MONZIO COMPAGNONI, Antonella Nespoli, Edda Pellegrini, Paolo Perego, Nadia Rovelli, Paola Sacchi, Luisa Scuratti, Rinaldo Zanini, Lora, Antonio, Andreoni, Giuseppe, Barri, Miriam, Frisone, Enrico, Fumagalli, Simona, Gargantini, Gianluigi, Leogrande, Melania, Magliano, Lorenza, Monzio Compagnoni, Matteo, Nespoli, Antonella, Pellegrini, Edda, Perego, Paolo, Rovelli, Nadia, Sacchi, Paola, Scuratti, Luisa, Zanini, Rinaldo, Lora, A, Andreoni, G, Barri, M, Frisone, E, Fumagalli, S, Gargantini, G, Leogrande, M, Magliano, L, MONZIO COMPAGNONI, M, Nespoli, A, Pellegrini, E, Perego, P, Rovelli, N, Sacchi, P, Scuratti, L, and Zanini, R

Subjects
perinatal depression, midwives, psycho-education, Midwive, Perinatal depression, Psycho-education
Abstract

The BLUES project: implementing innovative practices in screening and home care for women with perinatal depression Introduction Perinatal depression is frequent (1 woman out of 10 during the perinatal period), nonetheless to this day the screening is incomplete and the treatment gap is high. Materials and methods The BLUES project was financed by the Italian Ministry of Health and implemented in 10 Local Health Units of Lombardy Region. It had the goals of improving screening and implementing home visiting for women with perinatal depression. As far as the first goal, a smartphone app searchable by authorized professionals has been developed for transmitting screening tools (Edinburgh Postnatal Depression Scale - EPDS - and Whooley questions) to a cloud database; the app was also connected to a free website informing on mental health during the perinatal period. As far as the second goal, a home visiting programme was implemented according to the WHO Thinking Healthy method. A total of 110 professionals (most midwives), working in the family care centers, attended a structured training course in the Thinking Healthy approach and then applied the intervention to women during the perinatal period. The effectiveness and feasibility of the intervention were assessed at its completion (pre-post comparisons). Results The smartphone app and the related website were successfully activated in family care centers in the Province of Lecco (Lombardy, Italy). 39 women responding to selection criteria (EPDS ≥ 10 and a diagnosis of depression) were recruited for the home visiting intervention: 31 of them have completed the Thinking Healthy program. A clinically significant reduction of the EPDS scores was assessed in 80% of the women with moderate depressive symptoms (EPDS score ≥ 12). Both women and professionals evaluated the intervention useful and acceptable. Conclusions The BLUES project improved the screening using e-tools and implemented home visiting following the Thinking Healthy method. The process of task shifting from mental health sector to midwives was successful, while professionals met difficulties in balancing home visiting activities and routine activities.

Published
2022

18. Childbirth care among sars-cov-2 positive women in Italy

Author

Donati, Serena, Corsi, Edoardo, Salvatore, Michele, Maraschini, Alice, Bonassisa, Silvia, Casucci, Paola, Cataneo, Ilaria, Cetin, Irene, D’Aloja, Paola, Dardanoni, Gabriella, Ambrosi, Elena De, Ferrazzi, Enrico, Fieni, Stefania, Franchi, Massimo, Gargantini, Gianluigi, Iurlaro, Enrico, Leo, Livio, Liberati, Marco, Livio, Stefania, Locci, Mariavittoria, Marozio, Luca, Martini, Claudio, Maso, Gianpaolo, Mecacci, Federico, Meloni, Alessandra, Mignuoli, Anna, Patanè, Luisa, Pellegrini, Edda, Perotti, Francesca, Perrone, Enrica, Prefumo, Federico, Ramenghi, Luca, Rusciani, Raffaella, Savasi, Valeria, Schettini, Sergio, Simeone, Daniela, Simeone, Serena, Spinillo, Arsenio, Steinkasserer, Martin, Tateo, Saverio, Ternelli, Giliana, Tironi, Roberta, Trojano, Vito, Vergani, Patrizia, Zullino, Sara, Group, on behalf of the ItOSS COVID-19 Working, Donati, Serena, Corsi, Edoardo, Salvatore, Michele Antonio, Maraschini, Alice, Bonassisa, Silvia, Casucci, Paola, Cataneo, Ilaria, Cetin, Irene, D'Aloja, Paola, Dardanoni, Gabriella, De Ambrosi, Elena, Ferrazzi, Enrico, Fieni, Stefania, Franchi, Massimo Piergiuseppe, Gargantini, Gianluigi, Iurlaro, Enrico, Leo, Livio, Liberati, Marco, Livio, Stefania, Locci, Mariavittoria, Marozio, Luca, Martini, Claudio, Maso, Gianpaolo, Mecacci, Federico, Meloni, Alessandra, Mignuoli, Anna Domenica, Patanè, Luisa, Pellegrini, Edda, Perotti, Francesca, Perrone, Enrica, Prefumo, Federico, Ramenghi, Luca, Rusciani, Raffaella, Savasi, Valeria, Schettini, Sergio Crescenzo Antonio, Simeone, Daniela, Simeone, Serena, Spinillo, Arsenio, Steinkasserer, Martin, Tateo, Saverio, Ternelli, Giliana, Tironi, Roberta, Trojano, Vito, Vergani, Patrizia, Zullino, Sara, Donati, S, Corsi, E, Salvatore, M, Maraschini, A, Bonassisa, S, Casucci, P, Cataneo, I, Cetin, I, D'Aloja, P, Dardanoni, G, De Ambrosi, E, Ferrazzi, E, Fieni, S, Franchi, M, Gargantini, G, Iurlaro, E, Leo, L, Liberati, M, Livio, S, Locci, M, Marozio, L, Martini, C, Maso, G, Mecacci, F, Meloni, A, Mignuoli, A, Patane, L, Pellegrini, E, Perotti, F, Perrone, E, Prefumo, F, Ramenghi, L, Rusciani, R, Savasi, V, Schettini, S, Simeone, D, Simeone, S, Spinillo, A, Steinkasserer, M, Tateo, S, Ternelli, G, Tironi, R, Trojano, V, Vergani, P, and Zullino, S

Subjects
Perinatal care, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Infectious Disease Transmission, Breastfeeding, 0302 clinical medicine, Pregnancy, Health care, Childbirth, Vertical, 030212 general & internal medicine, Prospective Studies, Pregnancy Complications, Infectious, Prospective cohort study, Child, education.field_of_study, 030219 obstetrics & reproductive medicine, Obstetrics, Infectious, Italy, Cohort, Medicine, Female, Human, medicine.medical_specialty, Population, Article, 03 medical and health sciences, medicine, Humans, Caesarean section, education, business.industry, SARS-CoV-2, Cesarean Section, Public Health, Environmental and Occupational Health, Infant, Newborn, COVID-19, Infant, medicine.disease, Newborn, Infectious Disease Transmission, Vertical, Pregnancy Complications, Prospective Studie, Birth, business
Abstract

The new coronavirus emergency spread to Italy when little was known about the infection’s impact on mothers and newborns. This study aims to describe the extent to which clinical practice has protected childbirth physiology and preserved the mother–child bond during the first wave of the pandemic in Italy. A national population-based prospective cohort study was performed enrolling women with confirmed SARS-CoV-2 infection admitted for childbirth to any Italian hospital from 25 February to 31 July 2020. All cases were prospectively notified, and information on peripartum care (mother–newborn separation, skin-to-skin contact, breastfeeding, and rooming-in) and maternal and perinatal outcomes were collected in a structured form and entered in a web-based secure system. The paper describes a cohort of 525 SARS-CoV-2 positive women who gave birth. At hospital admission, 44.8% of the cohort was asymptomatic. At delivery, 51.9% of the mothers had a birth support person in the delivery room, the average caesarean section rate of 33.7% remained stable compared to the national figure. On average, 39.0% of mothers were separated from their newborns at birth, 26.6% practised skin-to-skin, 72.1% roomed in with their babies, and 79.6% of the infants received their mother’s milk. The infants separated and not separated from their SARS-CoV-2 positive mothers both had good outcomes. At the beginning of the pandemic, childbirth raised awareness and concern due to limited available evidence and led to “better safe than sorry” care choices. An improvement of the peripartum care indicators was observed over time.

Published
2021

19. COVID-19 Obstetrics Task Force, Lombardy, Italy: Executive management summary and short report of outcome

Author

Gianluigi Gargantini, Enrico Ferrazzi, Luigi Frigerio, Arsenio Spinillo, Patrizia Vergani, Federico Prefumo, Irene Cetin, Edda Pellegrini, Ferrazzi, E, Frigerio, L, Cetin, I, Vergani, P, Spinillo, A, Prefumo, F, Pellegrini, E, and Gargantini, G

Subjects
Coronavirus disease 2019 (COVID-19), Maternity, Pneumonia, Viral, Maternity hospitals, Hospitals, Maternity, Ambulatory Care Facilities, Hospitals, Special, Obstetric care, 03 medical and health sciences, 0302 clinical medicine, Obstetrics and Gynaecology, Medicine, Humans, 030212 general & internal medicine, Viral, Human resources, Personal protective equipment, Pandemics, Personal Protective Equipment, 030219 obstetrics & reproductive medicine, Health Care Rationing, Special, business.industry, Task force, SARS-CoV-2, Obstetrics and Gynecology, COVID-19, pregnancy, Female, Italy, Obstetrics, Patient Care, Pregnancy, Coronavirus Infections, Pneumonia, General Medicine, Interim analysis, medicine.disease, Hospitals, Medical emergency, Presentation (obstetrics), business
Abstract

From February 24, 2020, a COVID-19 obstetric task force was structured to deliver management recommendations for obstetric care. From March 1, 2020, six COVID-19 hubs and their spokes were designated. An interim analysis of cases occurring in or transferred to these hubs was performed on March 20, 2020 and recommendations were released on March 24, 2020. The vision of this strict organization was to centralize patients in high-risk maternity centers in order to concentrate human resources and personal protective equipment (PPE), dedicate protected areas of these major hospitals, and centralize clinical multidisciplinary experience with this disease. All maternity hospitals were informed to provide a protected labor and delivery room for nontransferable patients in advanced labor. A pre-triage based on temperature and 14 other items was developed in order to screen suspected patients in all hospitals to be tested with nasopharyngeal swabs. Obstetric outpatient facilities were instructed to maintain scheduled pregnancy screening as per Italian guidelines, and to provide pre-triage screening and surgical masks for personnel and patients for pre-triage-negative patients. Forty-two cases were recorded in the first 20 days of hub and spoke organization. The clinical presentation was interstitial pneumonia in 20 women. Of these, seven required respiratory support and eventually recovered. Two premature labors occurred.

Published
2020

20. Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease

Author

Egidio Romero, Patrizia Cambieri, Gianluigi Gargantini, Stefano Berrè, M. Debiaggi, Massimo Clementi, Michela Sampaolo, Filippo Canducci, Cristina Terulla, Maria Chiara Marinozzi, Canducci, F, Debiaggi, M, Sampaolo, M, Marinozzi, Mc, Berrè, S, Terulla, C, Gargantini, G, Cambieri, P, Romero, E, and Clementi, Massimo

Subjects
Male, viruses, Molecular Sequence Data, coronavirus, Comorbidity, Respiratory Syncytial Virus Infections, medicine.disease_cause, Virus, Article, bocavirus, Parvoviridae Infections, Nidovirales, Virology, respiratory viruses, Genotype, medicine, Prevalence, Coronaviridae, Humans, Prospective Studies, Respiratory system, Pathogen, Respiratory Tract Infections, Coronavirus, Paramyxoviridae Infections, biology, Human bocavirus, Infant, Newborn, virus diseases, Infant, RSV, Sequence Analysis, DNA, biology.organism_classification, Respiratory Syncytial Viruses, Infectious Diseases, Italy, Child, Preschool, Immunology, DNA, Viral, hMPV, Pharynx, RNA, Viral, Female, Metapneumovirus, Coronavirus Infections, Research Article
Abstract

A prospective 2‐year analysis including 322 infant patients with acute respiratory disease (ARD) hospitalized in a pediatric department in northern Italy was carried out to evaluate the role as respiratory pathogens or co‐pathogens of recently identified viruses. The presence of respiratory syncitial virus (RSV), human Metapneumoviruses (hMPVs), human Bocaviruses (hBoVs), and human Coronaviruses (hCoVs) was assayed by molecular detection and clinical symptoms evaluated. Nasopharyngeal aspirates from 150 of the 322 infants (46.6%) tested positive for at least one pathogen. Ninety samples (28.0%) tested positive for RSV RNA (61.5% genotype A and 38.5% genotype B), 46 (14.3%) for hMPV RNA (71.7% subtype A and 28.3% subtype B), 28 (8.7%) for hCoV RNA (39.3% hCoV‐OC43, 35.7% hCoV‐NL63, 21.4% hCoV‐HKU1, and 3.6% hCoV‐229E), and 7 (2.2%) for hBoV DNA (of the 6 typed, 50% subtype 1 and 50% subtype 2); 21/150 samples revealed the presence of 2 or more viruses. Co‐infection rates were higher for hMPVs, hCoVs, and hBoV (38.3%, 46.4%, and 57.1%,) and lower for RSV (23.3%). RSV was associated with the presence of complications (P

Published
2008

21. Childbirth Care among SARS-CoV-2 Positive Women in Italy.

Author

Donati S, Corsi E, Salvatore MA, Maraschini A, Bonassisa S, Casucci P, Cataneo I, Cetin I, D'Aloja P, Dardanoni G, De Ambrosi E, Ferrazzi E, Fieni S, Franchi MP, Gargantini G, Iurlaro E, Leo L, Liberati M, Livio S, Locci M, Marozio L, Martini C, Maso G, Mecacci F, Meloni A, Mignuoli AD, Patanè L, Pellegrini E, Perotti F, Perrone E, Prefumo F, Ramenghi L, Rusciani R, Savasi V, Schettini SCA, Simeone D, Simeone S, Spinillo A, Steinkasserer M, Tateo S, Ternelli G, Tironi R, Trojano V, Vergani P, and Zullino S

Subjects
Cesarean Section, Child, Female, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical, Italy epidemiology, Pregnancy, Prospective Studies, SARS-CoV-2, COVID-19, Pregnancy Complications, Infectious epidemiology
Abstract

The new coronavirus emergency spread to Italy when little was known about the infection's impact on mothers and newborns. This study aims to describe the extent to which clinical practice has protected childbirth physiology and preserved the mother-child bond during the first wave of the pandemic in Italy. A national population-based prospective cohort study was performed enrolling women with confirmed SARS-CoV-2 infection admitted for childbirth to any Italian hospital from 25 February to 31 July 2020. All cases were prospectively notified, and information on peripartum care (mother-newborn separation, skin-to-skin contact, breastfeeding, and rooming-in) and maternal and perinatal outcomes were collected in a structured form and entered in a web-based secure system. The paper describes a cohort of 525 SARS-CoV-2 positive women who gave birth. At hospital admission, 44.8% of the cohort was asymptomatic. At delivery, 51.9% of the mothers had a birth support person in the delivery room; the average caesarean section rate of 33.7% remained stable compared to the national figure. On average, 39.0% of mothers were separated from their newborns at birth, 26.6% practised skin-to-skin, 72.1% roomed in with their babies, and 79.6% of the infants received their mother's milk. The infants separated and not separated from their SARS-CoV-2 positive mothers both had good outcomes. At the beginning of the pandemic, childbirth raised awareness and concern due to limited available evidence and led to "better safe than sorry" care choices. An improvement of the peripartum care indicators was observed over time.

Published
2021
Full Text
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22. COVID-19 Obstetrics Task Force, Lombardy, Italy: Executive management summary and short report of outcome.

Author

Ferrazzi EM, Frigerio L, Cetin I, Vergani P, Spinillo A, Prefumo F, Pellegrini E, and Gargantini G

Subjects
Ambulatory Care Facilities organization & administration, COVID-19, Female, Hospitals, Maternity organization & administration, Hospitals, Special organization & administration, Hospitals, Special standards, Humans, Italy, Personal Protective Equipment supply & distribution, Pregnancy, Ambulatory Care Facilities standards, Coronavirus Infections, Health Care Rationing organization & administration, Health Care Rationing standards, Hospitals, Maternity standards, Obstetrics standards, Pandemics, Patient Care standards, Pneumonia, Viral
Abstract

From February 24, 2020, a COVID-19 obstetric task force was structured to deliver management recommendations for obstetric care. From March 1, 2020, six COVID-19 hubs and their spokes were designated. An interim analysis of cases occurring in or transferred to these hubs was performed on March 20, 2020 and recommendations were released on March 24, 2020. The vision of this strict organization was to centralize patients in high-risk maternity centers in order to concentrate human resources and personal protective equipment (PPE), dedicate protected areas of these major hospitals, and centralize clinical multidisciplinary experience with this disease. All maternity hospitals were informed to provide a protected labor and delivery room for nontransferable patients in advanced labor. A pre-triage based on temperature and 14 other items was developed in order to screen suspected patients in all hospitals to be tested with nasopharyngeal swabs. Obstetric outpatient facilities were instructed to maintain scheduled pregnancy screening as per Italian guidelines, and to provide pre-triage screening and surgical masks for personnel and patients for pre-triage-negative patients. Forty-two cases were recorded in the first 20 days of hub and spoke organization. The clinical presentation was interstitial pneumonia in 20 women. Of these, seven required respiratory support and eventually recovered. Two premature labors occurred., (© 2020 International Federation of Gynecology and Obstetrics.)

Published
2020
Full Text
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23. Monitoring the hospital management of acute asthma: the Italian Pediatric Network experience.

Author

Martelli AG, Bianchi R, Boldrighini B, Bosoni M, De Vuono A, Flores D'Arcais A, Gargantini G, Longhi R, Ortisi MT, Racchi E, and Parola L

Subjects
Adolescent, Child, Child, Preschool, Female, Humans, Infant, Italy, Male, Pediatrics methods, Asthma therapy, Guideline Adherence, Hospitals standards, Pediatrics standards, Quality Assurance, Health Care methods
Abstract

Background: The Study Group on Accreditation and Quality Improvement of the Italian Society of Pediatrics has developed an observational study about the hospital management of pediatric patients affected by severe asthma, in order to evaluate how the Guidelines for severe asthma in childhood are applied in the daily practice., Methods: This study included patients between 2 and 17 years, hospitalized or under short intensive observation for acute asthma. The data collection was carried out through the compilation of on-line forms. The statistical technique used was the Chi Square test., Results: 409 forms were filled in by 32 Italian Centers. 17% of the patients showed severe asthma, 59% moderate and 24% mild. On arrival at the Emergency Room the oximetry was measured in 95% of the patients, the respiratory rate in 64% while the heart rate in 88% of them. 48% of the children were exposed to chest X-ray. More than half of the children received oxygen therapy, 98.5% received short-acting beta-2 agonists and systemic steroid therapy was given to 82% of children, mainly orally. At discharge only half of the children were provided with written instructions for the management of any subsequent asthmatic episode. The analysis of the collected data highlights that not all the children had their oxygen saturation measured, although this parameter is one of the main indicators of disease severity, as well as the respiratory rate, which was detected in a minimal percentage of cases. The frequency of chest X-ray was extremely high, even though it does not have any indication in the majority of asthma cases. The evaluation of the therapeutic treatment denotes an adequate use of the oxygen therapy according to the oximetry values found on arrival, but an abuse of steroid therapy. Critical issues emerge at discharge: children are not always educated about the home management of the disease and the self-evaluation of the illness seriousness., Conclusion: The pediatric network has become an excellent system of monitoring of the clinical management of asthmatic children, highlighting strengths and weaknesses on which to focus actions of improvement.

Published
2016

24. In-hospital management of children with bacterial meningitis in Italy.

Author

Ciofi degli Atti M, Esposito S, Parola L, Ravà L, Gargantini G, and Longhi R

Subjects
Adolescent, Child, Child, Preschool, Female, Humans, Incidence, Infant, Infant, Newborn, Italy epidemiology, Male, Meningitis, Bacterial epidemiology, Disease Management, Inpatients, Meningitis, Bacterial therapy
Abstract

Background: Over the years 2009-2013, we conducted a prospective study within a network established by the Italian Society of Pediatrics to describe the in-hospital management of children hospitalized for acute bacterial meningitis in 19 Italian hospitals with pediatric wards., Methods: Hospital adherence to the study was voluntary; data were derived from clinical records. Information included demographic data, dates of onset of first symptoms, hospitalization and discharge; diagnostic evaluation; etiology; antimicrobial treatment; treatment with dexamethasone; in-hospital complications; neurological sequelae and status at hospital discharge. Characteristics of in-hospital management of patients were described by causative agent., Results: Eighty-five patients were identified; 49.4% had received an antimicrobial treatment prior to admission. Forty percent of patients were transferred from other Centers; the indication to seek for hospital care was given by the primary care pediatrician in 80% of other children. Etiological agent was confirmed in 65.9% of cases; the most common infectious organism was Neisseria meningitidis (34.1%), followed by Streptococcus pneumoniae (20%). Patients with pneumococcal meningitis had a significant longer interval between onset of first symptoms and hospital admission. Median interval between the physician suspicion of meningitis and in-hospital first antimicrobial dose was 1 hour (interquartile range [IQR]: 1-2 hours). Corticosteroids were given to 63.5% of cases independently of etiology; 63.0% of treated patients received dexamethasone within 1 hour of antibiotic treatment, and 41.2% were treated for ≤4 days. Twenty-nine patients reported at least one in-hospital complication (34.1%). Six patients had neurological sequelae at discharge (7.1%). No deaths were observed., Conclusions: We observed a rate of meningitis sequelae at discharge similar to that reported by other western countries. Timely assistance and early treatment could have contributed to the favorable outcome that was observed in the majority of cases. Adherence to recommendation for corticosteroid adjunctive therapy seems suboptimal, and should be investigated in further studies. Most meningitis cases were due to N. meningitidis and S. pneumoniae. Reaching and maintaining adequate vaccination coverage against pneumococcal and meningococcal invasive infections remains a priority to prevent bacterial meningitis cases.

Published
2014
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25. Adherence to guidelines for management of children hospitalized for acute diarrhea.

Author

Lo Vecchio A, Liguoro I, Bruzzese D, Scotto R, Parola L, Gargantini G, and Guarino A

Subjects
Acute Disease, Anti-Bacterial Agents therapeutic use, Antidiarrheals therapeutic use, Child, Preschool, Diarrhea diagnosis, Diarrhea etiology, Feeding Behavior, Female, Gastroenteritis complications, Gastroenteritis diagnosis, Humans, Infant, Italy, Male, Microbiological Techniques statistics & numerical data, Practice Guidelines as Topic, Probiotics therapeutic use, Prospective Studies, Diarrhea therapy, Gastroenteritis therapy, Guideline Adherence statistics & numerical data, Health Services Misuse statistics & numerical data, Hospitalization statistics & numerical data
Abstract

Background: The major burden of acute gastroenteritis (AGE) in childhood is related to its high frequency and the large number of hospitalizations, medical consultations, tests and drug prescriptions. The adherence to evidence-based recommendations for AGE management in European countries is unknown. The purpose of the study was to compare hospital medical interventions for children admitted for AGE with recommendations reported in the European Societies of Pediatric Gastroenterology, Hepatology and Nutrition and Pediatric Infectious Diseases guidelines., Methods: A multicenter prospective study was conducted in 31 Italian hospitals. Data on children were collected through an online clinical reporting form and compared with European Societies of Pediatric Gastroenterology, Hepatology and Nutrition and Pediatric Infectious Diseases guidelines for AGE. The main outcomes were the inappropriate hospital admissions and the percentage of compliance to the guidelines (full >90%, partial >80% compliance) based on the number and type of violations to evidence-based recommendations., Results: Six-hundred and twelve children (53.6% male, mean age 22.8 ± 15.4 months) hospitalized for AGE were enrolled. Many hospital admissions (346/602, 57.5%) were inappropriate. Once admitted, 20.6% (126/612) of children were managed in full compliance with the guidelines and 44.7% (274/612) were managed in partial compliance. The most common violations were requests for microbiologic tests (404; 35.8%), diet changes (310; 27.6%) and the prescription of non-recommended probiotics (161; 14.2%), antibiotics (103; 9.2%) and antidiarrheal drugs (7; 0.6%)., Conclusions: Inappropriate hospital admissions and medical interventions are still common in the management of children with AGE in Italy. Implementation of guidelines recommendations is needed to improve quality of care.

Published
2014
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27. Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease.

Author

Canducci F, Debiaggi M, Sampaolo M, Marinozzi MC, Berrè S, Terulla C, Gargantini G, Cambieri P, Romero E, and Clementi M

Subjects
Bocavirus genetics, Bocavirus isolation & purification, Child, Preschool, Comorbidity, Coronavirus genetics, Coronavirus isolation & purification, Coronavirus Infections physiopathology, Coronavirus Infections virology, DNA, Viral genetics, Female, Humans, Infant, Infant, Newborn, Italy epidemiology, Male, Metapneumovirus genetics, Metapneumovirus isolation & purification, Molecular Sequence Data, Paramyxoviridae Infections physiopathology, Paramyxoviridae Infections virology, Parvoviridae Infections physiopathology, Parvoviridae Infections virology, Pharynx virology, Prevalence, Prospective Studies, RNA, Viral genetics, Respiratory Syncytial Virus Infections complications, Respiratory Syncytial Virus Infections physiopathology, Respiratory Syncytial Viruses genetics, Respiratory Syncytial Viruses isolation & purification, Respiratory Tract Infections physiopathology, Respiratory Tract Infections virology, Sequence Analysis, DNA, Coronavirus Infections epidemiology, Paramyxoviridae Infections epidemiology, Parvoviridae Infections epidemiology, Respiratory Syncytial Virus Infections epidemiology, Respiratory Syncytial Virus Infections virology, Respiratory Tract Infections epidemiology
Abstract

A prospective 2-year analysis including 322 infant patients with acute respiratory disease (ARD) hospitalized in a pediatric department in northern Italy was carried out to evaluate the role as respiratory pathogens or co-pathogens of recently identified viruses. The presence of respiratory syncitial virus (RSV), human Metapneumoviruses (hMPVs), human Bocaviruses (hBoVs), and human Coronaviruses (hCoVs) was assayed by molecular detection and clinical symptoms evaluated. Nasopharyngeal aspirates from 150 of the 322 infants (46.6%) tested positive for at least one pathogen. Ninety samples (28.0%) tested positive for RSV RNA (61.5% genotype A and 38.5% genotype B), 46 (14.3%) for hMPV RNA (71.7% subtype A and 28.3% subtype B), 28 (8.7%) for hCoV RNA (39.3% hCoV-OC43, 35.7% hCoV-NL63, 21.4% hCoV-HKU1, and 3.6% hCoV-229E), and 7 (2.2%) for hBoV DNA (of the 6 typed, 50% subtype 1 and 50% subtype 2); 21/150 samples revealed the presence of 2 or more viruses. Co-infection rates were higher for hMPVs, hCoVs, and hBoV (38.3%, 46.4%, and 57.1%,) and lower for RSV (23.3%). RSV was associated with the presence of complications (P < 0.001) and hypoxia (P < 0.015). When the presence of RSV alone and the RSV-hMPV co-infections were considered, RSV mono-infected patients resulted to have longer hospitalization and higher hypoxia (P < 0.001). The data highlight that (i) RSV has a central role as a respiratory pathogen of infants, (ii) the wide circulation of recently identified viruses does not reduce the clinical and epidemiological importance of RSV, and that (iii) recently identified agents (hMPVs, hBoVs, and hCoVs) act as primary pathogens or co-pathogens.

Published
2008
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28. [Adolescents and health services: the hospital].

Author

Perletti L, Gargantini G, Masera N, and Frattini D

Subjects
Adolescent, Child, Child, Preschool, Humans, Infant, Infant, Newborn, Italy, Adolescent Health Services supply & distribution, Hospitals, Patient Admission
Published
1998

29. [The superior thoracic outlet compression syndrome: a report of a case in childhood with complete cervical rib].

Author

Nedbal M, Gargantini G, Frattini D, Mazzola G, and Perletti L

Subjects
Adolescent, Cervical Rib Syndrome surgery, Female, Humans, Remission Induction, Thoracic Outlet Syndrome surgery, Cervical Rib Syndrome diagnosis, Thoracic Outlet Syndrome diagnosis
Abstract

Authors report a paediatric patient with thoracic outlet syndrome (TOC) and complete cervical rib. The symptoms at the time of presentation result from pressure on either the subclavian vessels or the lower trunk of the brachial plexus. TOC is infrequent in young people and usually the symptomatology does'nt need a surgical approach. Some Authors affirm that there are necessary impulsive moments like growth, increased muscular mass and rib ossification, decreased elasticity of ligaments, vessels, muscles and nerves, for outcoming the clinical manifestations. Paediatric competention has risen until adolescent age and may be more frequent the observation of this syndrome that present problems of both diagnosis and management.

Published
1995

30. [Menkes' syndrome. Description of a clinical use].

Author

Gargantini G, Bonora G, Cambiè M, De La Pierre L, and Luciani L

Subjects
Cerebral Arteries abnormalities, Ceruloplasmin metabolism, Copper blood, Humans, Infant, Male, Brain Diseases, Metabolic, Menkes Kinky Hair Syndrome
Published
1983

32. [Ring chromosome 22. Description of a clinical case].

Author

Pizzi E, de la Pierre L, Gargantini G, Andreoli A, Rogari P, Bonora G, and Rossella F

Subjects
Child, Preschool, Humans, Male, Chromosome Aberrations diagnosis, Chromosome Disorders, Chromosomes, Human, Pair 22, Kidney abnormalities, Ring Chromosomes
Published
1987

33. [Neonatal stridor. Description of a case of double aortic arch].

Author

Gargantini G, Luciani L, and Castelli L

Subjects
Humans, Infant, Newborn, Male, Aorta, Thoracic abnormalities, Respiratory Sounds etiology
Abstract

Neonatal stridor often relates with a serious respiratory distress. We report a case of stridor appeared in tenth day of life. In this case of double aortic arch the surgical intervention at 25 days had a favourable outcome. Three months later the child was completely asymptomatic. An early diagnosis allows a prompt surgical approach with a favourable outcome. We outline the diagnostic procedure in neonatal stridor.

Published
1989

34. [The mesenteric artery syndrome].

Author

Cambiè M, Acerbi L, Bonora G, Gargantini G, and Bersani M

Subjects
Anorexia etiology, Body Weight, Child, Duodenal Obstruction etiology, Female, Humans, Vomiting etiology, Duodenal Obstruction complications, Superior Mesenteric Artery Syndrome complications
Abstract

We describe a case of superior mesenteric artery syndrome in a 12 years old girl. The patient had anorexia, emesis and weight loss. Rx-abdomen without and with contrast medium showed duodenum obstruction. The syndrome was associated with application of body cast.

Published
1983

36. [West syndrome in a case of congenital cutis aplasia].

Author

Mariani G, Luciani L, Bonora G, De La Pierre L, Gargantini G, and Pizzi E

Subjects
Female, Humans, Infant, Scalp Dermatoses complications, Ectodermal Dysplasia complications, Spasms, Infantile complications
Abstract

A case of West's syndrome in a four months old child affected with aplasia cutis congenita is described. The Authors suggest the possibility of a link between the two diseases.

Published
1984

37. [Spondylocostal dysostosis].

Author

Bonora G, Baronciani D, Gargantini G, and Dalprà L

Subjects
Dysostoses congenital, Female, Humans, Infant, Newborn, Karyotyping, Chromosome Inversion, Chromosomes, Human, 6-12 and X, Dysostoses genetics, Ribs abnormalities, Thoracic Vertebrae abnormalities
Abstract

A case with spondylocostal dysostosis is reported. The Authors emphasize the different prognosis of the autosomal recessive form in comparison with the autosomal dominant one. The association between pericentric inversion of chromosome 9 and this dysplasia is discussed.

Published
1985

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