1. Evaluation of critical congenital heart defects screening using pulse oximetry in the neonatal intensive care unit
- Author
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Van Naarden Braun, K, Grazel, R, Koppel, R, Lakshminrusimha, S, Lohr, J, Kumar, P, Govindaswami, B, Giuliano, M, Cohen, M, Spillane, N, Jegatheesan, P, McClure, D, Hassinger, D, Fofah, O, Chandra, S, Allen, D, Axelrod, R, Blau, J, Hudome, S, Assing, E, and Garg, LF
- Subjects
Heart Disease ,Cardiovascular ,Prevention ,Health Services ,Pediatric ,Perinatal Period - Conditions Originating in Perinatal Period ,Preterm ,Low Birth Weight and Health of the Newborn ,Clinical Research ,Infant Mortality ,Detection ,screening and diagnosis ,4.2 Evaluation of markers and technologies ,Reproductive health and childbirth ,Echocardiography ,Gestational Age ,Heart Defects ,Congenital ,Humans ,Infant ,Extremely Low Birth Weight ,Infant ,Newborn ,Infant ,Premature ,Intensive Care Units ,Neonatal ,Neonatal Screening ,Oximetry ,Oxygen Inhalation Therapy ,Prospective Studies ,Clinical Sciences ,Paediatrics and Reproductive Medicine ,Pediatrics - Abstract
ObjectiveTo evaluate the implementation of early screening for critical congenital heart defects (CCHDs) in the neonatal intensive care unit (NICU) and potential exclusion of sub-populations from universal screening.Study designProspective evaluation of CCHD screening at multiple time intervals was conducted in 21 NICUs across five states (n=4556 infants).ResultsOf the 4120 infants with complete screens, 92% did not have prenatal CHD diagnosis or echocardiography before screening, 72% were not receiving oxygen at 24 to 48 h and 56% were born ⩾2500 g. Thirty-seven infants failed screening (0.9%); none with an unsuspected CCHD. False positive rates were low for infants not receiving oxygen (0.5%) and those screened after weaning (0.6%), yet higher among infants born at
- Published
- 2017