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23,886 results on '"Garcia DE"'

1. Enhanced Free-Electron Wavefunction Modulation via Photon-Induced Near-Field Electron Microscopy (PINEM) with Shaped Light Fields

Author

Ferrari Beatrice, Duncan Cameron J., Ostroman Irene, Bravi Maria G., Rosi Paolo, Rotunno Enzo, Olaya Jean-Cristophe, Park S. T., Masiel D., Grillo Vincenzo, Kaminer Ido, Garcia de Abajo Francisco J., Lagrange Thomas, Carbone Fabrizio, and Vanacore Giovanni M.

Subjects
photon-induced near-field electron microscopy pinem, Microbiology, QR1-502, Physiology, QP1-981, Zoology, QL1-991
Published
2024
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2. A large colonial choanoflagellate from Mono Lake harbors live bacteria.

Author

Hake, K, West, P, McDonald, K, Laundon, D, Reyes-Rivera, J, Garcia De Las Bayonas, A, Feng, C, Burkhardt, P, Richter, D, Banfield, Jill, and King, Nicole

Subjects
Mono Lake, bacteria, choanoflagellates, evolution, fluorescence in situ hybridization, multicellularity, Choanoflagellata, Lakes, California, Phylogeny, Gammaproteobacteria, RNA, Ribosomal, 16S, Bacteria, Alphaproteobacteria, Sequence Analysis, DNA
Abstract

UNLABELLED: As the closest living relatives of animals, choanoflagellates offer insights into the ancestry of animal cell physiology. Here, we report the isolation and characterization of a colonial choanoflagellate from Mono Lake, California. The choanoflagellate forms large spherical colonies that are an order of magnitude larger than those formed by the closely related choanoflagellate Salpingoeca rosetta. In cultures maintained in the laboratory, the lumen of the spherical colony is filled with a branched network of extracellular matrix and colonized by bacteria, including diverse Gammaproteobacteria and Alphaproteobacteria. We propose to erect Barroeca monosierra gen. nov., sp. nov. Hake, Burkhardt, Richter, and King to accommodate this extremophile choanoflagellate. The physical association between bacteria and B. monosierra in culture presents a new experimental model for investigating interactions among bacteria and eukaryotes. Future work will investigate the nature of these interactions in wild populations and the mechanisms underpinning the colonization of B. monosierra spheres by bacteria. IMPORTANCE: The diversity of organisms that live in the extreme environment of Mono Lake (California, USA) is limited. We sought to investigate whether the closest living relatives of animals, the choanoflagellates, exist in Mono Lake, a hypersaline, alkaline, arsenic-rich environment. We repeatedly isolated members of a new species of choanoflagellate, which we have named Barroeca monosierra. Characterization of B. monosierra revealed that it forms large spherical colonies containing diverse co-isolated bacteria, providing an opportunity to investigate mechanisms underlying physical associations between eukaryotes and bacteria.

Published
2024

3. Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study

Author

T Richards, S Shaikh, S Rehman, A Khan, J Shah, C Smith, A Brown, S Singh, A P Arnaud, A Young, D Bowen, P Patel, S Williams, J Dunn, J John, M Loubani, A Hainsworth, A Kolias, PJ Hutchinson, R Singh, S Sinha, S Shaw, J Edwards, S Mukherjee, AAB Jamjoom, A Singh, S Saeed, J Martin, S Smith, S Ross, M Mohan, P Hutchinson, G James, RDC Moon, P Brennan, A Williams, S Brown, A Ward, M Lee, K Thompson, S Ali, J Williams, S Reid, U Khan, J Lambert, A Smith, B Singh, M Hassan, N Sharma, J Reynolds, N Wright, T Williams, H Smith, M Ng, M Rahman, A Taylor, P Shah, D Saxena, J Evans, I Omar, M Ali, A Hanson, Z Li, R Andrade, P Cardoso, H Jeong, P Sharma, M Arrieta, J Clark, L Pearce, J McVeigh, V Sharma, B Kim, J Singh, S Newman, J Byrne, A Hassan, A Persad, A Gardner, H Liu, K Shah, I Hughes, S Davison, A Balakrishnan, K Patel, J Hall, S Mistry, J Parry, R Baumber, N McGrath, E Ross, R Mannion, S Murphy, FL Wright, A Rogers, B Rai, M Thomas, R Ribeiro, E Hamilton, J Teixeira, B Davidson, L Carvalho, R Garrido, A Puppo, A Guimarães, E Santos, M Kamal, M Denning, M Elhadi, J E Fitzgerald, D Miller, M Gowda, C Morris, A Phillips, H Yang, Y Zhang, N Machairas, A Fisher, A Kaufmann, A Aggarwal, L Hansen, M Otify, H Soleymani Majd, A Jones, M Rodrigues, S Sundar, C Jones, R Edmondson, A Sharkey, L Smith, G Williams, J Dunning, E Belcher, D Stavroulias, V Zamvar, M Patel, M Baker, R Evans, M Sherif, J Hopkins, R Mohammed, A Hill, H Jackson, G Jones, K George, J Dixon, A Tong, S Jallad, Deborah S Keller, A Pereira, L Elliott, D Ford, A Sermon, M Almond, Andrew Metcalfe, C Peluso, T White, S Shah, A Witek, Chetan Khatri, A Tiwari, T Lo, K Agarwal, C Sweeney, C Hart, T Holme, S Green, I Ahmed, A Sobti, C Anderson, N Modi, R Campbell, C Magee, M Mirza, D Jones, N Stylianides, X Luo, C Kang, J Ribeiro, L Kumar, J Diaz, A Bhalla, R Young, C Perkins, A James, A Walters, J Reid, R Pereira, C McDonald, A Aujayeb, K Jackson, M Allen, D Ghosh, M Chan, C Price, K Khan, R Moore, M Ibrahim, A Marchbank, M Silva, M Baig, J De Coster, J Castellanos, S Saxena, M Duque, E Li, E Martin, A Isik, J González, RJ Davies, B Smith, R Owen, K Lakhoo, M Rogers, MA Akhtar, K Mellor, S Agrawal, L Foster, G Harris, J McIntyre, M Garner, R West, R Cuthbert, D Johnson, H Gomes, C Roy, N Spencer, D Mehta, J Freedman, J Blair, K Rajput, K Williams, J Wall, A Soliman, F Chen, A Mokhtari, I Mohamed, J Pascoe, M Khalifa, R Das, A Lara, M Costa, A Mahmoud, K Roberts, J Lane, S Robertson, J P Evans, E Krishnan, I Haq, S Rogers, J Knowles, M Chowdhury, A Ghanbari, L Macdonald, S Powell, J Hunt, J Cornish, J Engel, S Page, I Blake, A Rolls, H Ross, D Simpson, J Hammond, A Goyal, K Parkins, A Desai, A Gaunt, A Salim, Y Yousef, A Schache, H Mohan, SR Brown, R Nair, M Flatman, J Lord, RJ Egan, R Harries, N Judkins, K Sugand, T Hine, J Luck, C Johnson, G Salerno, AW Phillips, R Houston, A Volpe, C Walker, C Steele, M Rela, C Barry, R Alves, L Ramsay, A Turnbull, A Daniele, C S Jones, P Gallagher, G Gradinariu, A Oliveira, C Hardie, H Ferguson, S Bhattacharya, E Davies, P Joshi, C Mellor, E Griffiths, A Bhangu, R Mahoney, F Kashora, G Ruiz, K Wong, G Hill, V Testa, S Ford, C Park, P Gomez, C Lopes, A Lázaro, A Shabana, A Agarwal, C Chung, C Politis, G Martin, E Chung, M Ismail, C Cunha, S Correia, I Santos, A Tang, A Robson, T Collier, G Baltazar, M Quintana, C English, M Ip, K Newton, J Kahn, C Tan, D Cheng, R Woods, M Ho, A ABBAS, A Henry, F Rivas, M Mohammed, N Parsons, T Board, S Madan, A Osorio, M Jarvis, M Hashem, A Egglestone, E Halliday, A Ridgway, G Gallo, J Gilliland, W Marx, R Shaw, A Mahmood, K Gohil, B Gallagher, D Alderson, A Karim, G D Stewart, G Peck, L Majkowski, J Carter, H Ishii, L HUMPHREYS, J Khan, S Abbott, C Newton, F Borghi, A Sud, K Bhatia, H Cao, V Vijay, L Sanderson, E Holler, N Hanna, D Ferguson, P Miranda, L Pickering, T Singhal, T Newman, K Ghosh, C Camacho, D Manning, C Lipede, R Clifford, S Higgs, C Menakaya, S Shankar, K Booth, M Abdalla, T Nelson, T Farrell, H Naseem, J Johnstone, A Wilkins, A Brunt, A Nogués, A Patience, D Jeevan, M Vatish, G Stables, S Adegbola, I Hunt, K Dickson, W Matthews, N Dunne, M Maher, G Faulkner, E Hernandez, R Sofat, K Sahnan, A Brunelli, M Raza, K Chui, C Brennan, P Vaughan, H Chu, R Hagger, ASD Liyanage, R Perkins, S Duff, C Gill, H Dean, S Bandyopadhyay, K Ragupathy, Y Cunningham, A Bateman, V Brown, B Ho, E Britton, H Ikram, R Hasan, A Colquhoun, S Handa, A Maqsood, M Caputo, J Torkington, G Fusai, N Hossain, DJ Lin, S Stefan, IR Daniels, D Pournaras, A Askari, P Nisar, S Moug, J Sagar, N Yassin, G Minto, Z Hamady, JR O'Neill, S Chowdhury, R Cresner, D Vimalachandran, FD Mcdermott, RP Jones, P Zerbib, L Sreedharan, S Wahed, SS Gisbertz, MI van Berge Henegouwen, R Preece, I Liew, S McCluney, D Watts, D Nehra, B Dean, D Chaudhry, L Ross, F Solari, S Chatterji, B Barmayehvar, S Lourenco, L Onos, F Mansour, A Radhakrishnan, M Varcada, M Richmond, I Hernández, A Spinelli, H Pham, J Shalhoub, F Wells, K Bevan, A Peckham-Cooper, N Campain, J Steinke, R Wilkin, K McEvoy, S Mastoridis, N Fine, J Bayer, Y Joshi, A Yener, S C McKay, NS Kalson, S Horvath, H Fu, A Parente, SE Lewis, Y Ahmad, G Seidel, M Dunstan, U von Oppell, J Vatish, H Hirsch, K Breen, C Dott, D Mathieu, J Hardie, K Aldridge, A Doorgakant, P Petrone, R Tansey, M El Amrani, C Branco, Y Viswanath, A Meagher, B Keeler, N Tewari, A Gabr, J Kinross, M Longhi, E M Harrison, P Daliya, P Asaad, F Langlands, N Misra, S Kristinsson, S Di Saverio, C Conso, H Roy, E Massie, L Masterson, D Baskaran, A Hannah, O Ismail, S URBAN, J Domenech, S Ranjit, L Massey, S Mannan, D Rutherford, F Colombo, R Kulkarni, D Kearney, Neil J Smart, G Bourke, D Shrestha, P Nankivell, O Breik, R Exley, D Zakai, AK Abou-Foul, P Naredla, R Vidya, G Mundy, H Marin, A E Ward, A Sudarsanam, W Singleton, M Ganau, F Moura, J Blanco, R Myatt, S Sousa, H Zahid, S Garrido, A Fell, E Caruana, D Nepogodiev, F Dhaif, B Bankhad-Kendall, H Kaafarani, C Bretherton, L Marais, K Siaw-Acheampong, B E Dawson, J C Glasbey, R R Gujjuri, E Heritage, S K Kamarajah, J M Keatley, S Lawday, G Pellino, J F F Simoes, I M Trout, M L Venn, R J W Wilkin, A O Ademuyiwa, E Al Ameer, O Alser, K M Augestad, B Bankhead-Kendall, R A Benson, S Chakrabortee, R Blanco-Colino, A Brar, A Minaya Bravo, K A Breen, I Lima Buarque, M F Cunha, G H Davidson, S Farik, M Fiore, G M A Gomes, C Halkias, I Lawani, H Lederhuber, S Leventoglu, M W Loffler, H Mashbari, D Mazingi, D Moszkowicz, J S Ng-Kamstra, S Metallidis, M Niquen, F Ntirenganya, O Outani, F Pata, T D Pinkney, P Pockney, D Radenkovic, A Ramos-De la Medina, A Schnitzbauer, S Shu, K Soreide, S Tabiri, P Townend, G Tsoulfas, G van Ramshorst, Mak JKC, F Tirotta, A Kisiel, LD Cato, AM Pathanki, A Chebaro, K Lecolle, S Truant, FR Pruvot, E Surmei, L Mattei, J Dudek, S El-Hasani, J Cuschieri, GH Davidson, RG Wade, H Elkadi, C Pompili, JR Burke, E Bagouri, Z Abual-Rub, S Munot, M Kowal, SC Winter, F Di Chiara, K Wallwork, A Qureishi, M Lami, S Sravanam, S Chidambaram, R Smillie, AV Shaw, C Cernei, D Jeyaretna, RJ Piper, E Duck, C Jelley, SC Tucker, G Bond-Smith, XL Griffin, GD Tebala, N Neal, TM Noton, H Ghattaura, OBF Risk, H Kharkar, C Verberne, A Senent-Boza, A Sánchez-Arteaga, I Benítez-Linero, F Manresa-Manresa, L Tallón-Aguilar, L Melero-Cortés, MR Fernández-Marín, VM Durán-Muñoz-Cruzado, I Ramallo-Solís, P Beltrán-Miranda, F Pareja-Ciuró, BT Antón-Eguía, AC Dawson, A Drane, F Oliva Mompean, J Gomez-Rosado, J Reguera-Rosal, J Valdes-Hernandez, L Capitan-Morales, del Toro Lopez, A Alanbuki, O Usman, AJ Beamish, D Bosanquet, D Magowan, H Nassa, G Mccabe, D Holroyd, NB Jamieson, NM Mariani, V Nicastro, D Motter, C Jenvey, T Minto, DR Sarma, C Godbole, W Carlos, A Khajuria, H Connolly, G Di Taranto, S Shanbhag, J Skillman, M Sait, H Al-omishy, B Heer, R Lunevicius, ARG Sheel, M Sundhu, AJA Santini, Fathelbab MSAT, KMA Hussein, QM Nunes, K Shahzad, Baig MMAS, JL Hughes, A Kattakayam, SB Shah, AL Clynch, N Georgopoulou, HM Sharples, AA Apampa, IC Nzenwa, D Podolsky, NL Coleman, MP Callahan, P Beak, I Gerogiannis, A Ebrahim, A Alwadiya, C Demetriou, E Grimley, E Theophilidou, E Ogden, FL Malcolm, G Davies-Jones, Ng JCK, N Elmaleh, Z Chia, J A'Court, A Konarski, R Talwar, P S Jambulingam, A Maity, C Hatzantonis, S Kudchadkar, N Cirocchi, CH Chan, H Eberbach, B Erdle, R Sandkamp, G Velmahos, LR Maurer, M El Moheb, A Gaitanidis, L Naar, MA Christensen, C Kapoen, K Langeveld, M El Hechi, B Main, T Maccabe, NS Blencowe, DP Fudulu, D Bhojwani, M Baquedano, F Rapetto, O Flannery, D Tadross, C Blundell, S Forlani, S Guha, CJ Kelty, G Chetty, G Lye, SP Balasubramanian, N Sureshkumar Shah, A Al-mukhtar, E Whitehall, A Giblin, A Adamec, J Konsten, M Van Heinsbergen, A Sou, J Jimeno Fraile, D Morales-Garcia, M Carrillo-Rivas, E Toledo Martínez, Pascual À, A Landaluce-olavarria, M Gonzalez De miguel, Fernández Gómez Cruzado L, E Begoña, D Lecumberri, A Calvo Rey, GM Prada hervella, L Dos Santos Carregal, MI Rodriguez Fernandez, M Freijeiro, S El Drubi Vega, J Van den Eynde, W Oosterlinck, R Van den Eynde, A Boeckxstaens, A Cordonnier, J Jaekers, M Miserez, M Galipienso Eri, JD Garcia Montesino, J Dellonder Frigolé, D Noriego Muñoz, V Lizzi, F Vovola, A Arminio, A Cotoia, AL Sarni, M Bekheit, BS Kamera, M Elhusseini, A Ahmeidat, W Cymes, G Mignot, J Agilinko, A Sgrò, MM Rashid, K Milne, KE Stewart, MSJ Wilson, K McGivern, BC Brown, B Wadham, IA Aneke, J Collis, H Warburton, DM Fountain, R Laurente, KV Sigamoney, M Dasa, Z Naqui, M Galhoum, MT Hasan, R Kalenderov, O Pathmanaban, R Chelva, K Subba, M Khalefa, F Hossain, T Moores, J Anthoney, O Emmerson, R Makin-Taylor, CS Ong, R Callan, O Bloom, G Chauhan, J Kaur, A Burahee, S Bleibleh, N Pigadas, D Snee, S Bhasin, A Crichton, A Habeebullah, AS Bodla, M Mondragon, V Dewan, MC Giuffrida, A Marano, S Palagi, S Di Maria Grimaldi, A Simonato, M D'Agruma, R Chiarpenello, L Pellegrino, F Maione, D Cianflocca, Pruiti Ciarello, G Giraudo, E Gelarda, E Dalmasso, A Abrate, V Ciriello, F Rosato, A Garnero, L Leotta, M Chiozza, G Anania, A Urbani, M Koleva Radica, P Carcoforo, M Portinari, M Sibilla, JE Archer, A Odeh, N Siddaiah, H Carmichael, CG Velopulos, RC McIntyre, TJ Schroeppel, EA Hennessy, L Zier, C Parmar, JM Muñoz Vives, CJ Gómez Díaz, CA Guariglia, C Soto Montesinos, L Sanchon, M Xicola Martínez, N Guàrdia, P Collera, R Diaz Del Gobbo, R Sanchez Jimenez, R Farre Font, R Flores Clotet, CEM Brathwaite, H Hakmi, AH Sohail, R Heckburn, D Townshend, N McLarty, A Shenfine, K Madhvani, M Hampton, AP Hormis, V Miu, K Sheridan, C Luney, MA Williams, A Alqallaf, A Ben-Sassi, R Crichton, J Sonksen, GR Layton, B Karki, S Pankhania, S Asher, A Folorunso, J Winyard, J Mangwani, BHB Babu, C Weerasinghe, M Ballabio, P Bisagni, T Armao, M Madonini, A Gagliano, P Pizzini, A Älgå, M Nordberg, G Sandblom, J El Kafsi, K Logishetty, A Saadya, R Midha, H Subbiah Ponniah, T Stockdale, T Bacarese-Hamilton, N Anjarwalla, D Marujo Henriques, R Hettige, C Baban, A Tenovici, F Anazor, SD King, S Kazzaz, S HKruijff, De Vries JPPM, PJ Steinkamp, PKC Jonker, WY Van der Plas, W Bierman, Y Janssen, ABJ Borgstein, D Enjuto, M Perez Gonzalez, P Díaz Peña, M Marqueta De Salas, P Martinez Pascual, L Rodríguez Gómez, R Garcés García, A Ramos Bonilla, N Herrera-Merino, P Fernández Bernabé, EP Cagigal Ortega, García de Castro Rubio E, I Cervera, MH Siddique, C Barmpagianni, A Basgaran, A Basha, V Okechukwu, A Bartsch, CA Leo, HK Ubhi, N Zafar, H Abdul-Jabar, F Mongelli, M Bernasconi, M Di Giuseppe, D Christoforidis, D La Regina, M Arigoni, A Al-Sukaini, S Mediratta, O Brown, M Boal, S Stanger, H Abdalaziz, J Constable, G Dovell, R Gopi reddy, A Dehal, HB Shah, GWV Cross, P Seyed-Safi, YW Smart, A Kuc, M Al-Yaseen, B Jayasankar, D Balasubramaniam, K Abdelsaid, N Mundkur, RE Soulsby, O Ryska, T Raymond, P Hawkin, G Kinnaman, I Sharma, K Freystaetter, JN Hadfield, A Hilley, S Arkani, M Youssef, I Shaikh, K Seebah, V Kouritas, D Chrastek, G Maryan, DF Gill, F Khatun, J Parakh, V Sarodaya, A Daadipour, KD Bosch, V Bashkirova, LS Dvorkin, VK Kalidindi, A Choudhry, M Espino Segura-Illa, G Sánchez Aniceto, AM Castaño-Leon, L Jimenez-Roldan, J Delgado Fernandez, A Pérez Núñez, A Lagares, D Garcia Perez, M Santas, I Paredes, O Esteban Sinovas, L Moreno-Gomez, E Rubio, V Vega, A Vivas Lopez, M Labalde Martinez, O García Villar, PM Pelaéz Torres, J Garcia Borda, E Ferrero Herrero, C Eiriz Fernandez, C Ojeda-Thies, JM Pardo Garcia, H Wynn Jones, H Divecha, C Whelton, E Powell-Smith, M Alotaibi, A Maashi, A Zowgar, M Alsakkaf, O Izquierdo, D Ventura, D Escobar, U Garcia de cortazar, Villamor Garcia, A Cioci, K Rakoczy, W Pavlis, R Saberi, A Khaleel, A Unnithan, K Memon, RR Pala Bhaskar, F Maqboul, F Kamel, A Al-Samaraee, R Madani, H Llaquet Bayo, N Duchateau, C De Gheldere, A Fayad, ML Wood, G Groot, I Hakami, C Boeker, J Mall, AF Haugstvedt, ML Jönsson, P Caja Vivancos, Villalabeitia Ateca, M Prieto Calvo, P Martin Playa, A Gainza, EJ Aragon Achig, A Rodriguez Fraga, Melchor Corcóstegui, G Mallabiabarrena Ormaechea, JJ Garcia Gutierrez, L Barbier, MA Pesántez Peralta, M Jiménez Jiménez, JA Municio Martín, J Gómez Suárez, G García Operé, LA Pascua Gómez, M Oñate Aguirre, A Fernandez-Colorado, M De la Rosa-Estadella, A Gasulla-Rodriguez, M Serrano-Martin, A Peig-Font, S Junca-Marti, M Juarez-Pomes, S Garrido-Ondono, L Blasco-Torres, M Molina-Corbacho, Y Maldonado-Sotoca, A Gasset-Teixidor, J Blasco-Moreu, V Turrado-Rodriguez, AM Lacy, FB de Lacy, X Morales, A Carreras-Castañer, P Torner, M Jornet-Gibert, M Balaguer-Castro, M Renau-Cerrillo, P Camacho-Carrasco, M Vives-Barquiel, B Campuzano-Bitterling, I Gracia, R Pujol-Muncunill, M Estaire Gómez, D Padilla-Valverde, S Sánchez-García, D Sanchez-Pelaez, E Jimenez Higuera, R Picón Rodríguez, Fernández Camuñas À, C Martínez-Pinedo, EP Garcia Santos, V Muñoz-Atienza, A Moreno Pérez, CA Cano, D Crego-Vita, M Huecas-Martinez, A Roselló Añón, MJ Sangüesa, JC Bernal-Sprekelsen, JC Catalá Bauset, P Renovell Ferrer, C Martínez Pérez, O Gil-Albarova, J Gilabert Estellés, K Aghababyan, R Rivas, J Escartin, JL Blas Laina, B Cros, Talal El-Abur, J Garcia Egea, C Yanez, JH Kauppila, E Sarjanoja, S Tzedakis, PA Bouche, S Gaujoux, D Gossot, A Seguin-Givelet, D Fuks, M Grigoroiu, R Sanchez Salas, X Cathelineau, P Macek, Y Barbé, F Rozet, E Barret, A Mombet, N Cathala, E Brian, F Zadegan, AJ Baldwin, E Gammeri, A Catton, S Marinos Kouris, J Pereca, M Kaushal, A Kler, V Reghuram, S Tezas, V Oktseloglou, F Mosley, MFI De La Cruz Monroy, P Bobak, S Ahad, E Lostis, GK Ambler, J Manara, M Doe, T Jichi, GD Stewart, J Ramzi, AA Singh, J Ashcroft, OJ Baker, P Coughlin, Durst AZED, A Abood, A Habeeb, VE Hudson, B Lamb, L Luke, S Mitrasinovic, Ngu AWT, S Waseem, F Georgiades, XS Tan, J Pushpa-rajah, I Abu-Nayla, S Rooney, E Irune, MHV Byrne, A Durrani, A Sethuraman Venkatesan, T Combellack, G Tahhan, M Kornaszewska, V Valtzoglou, I Deglurkar, M Koutentakis, Syed Nong Chek SAH, M Shinkwin, F Ayeni, H Tustin, M Bordenave, N Manu, N Eardley, OL Serevina, S Roy Mahapatra, K Mohankumar, I Khawaja, A Palepa, T Doulias, Y Premakumar, Y Jauhari, Z Koshnow, A Uberai, F Hirri, BM Stubbs, J Manickavasagam, S Dalgleish, R Kanitkar, CJ Payne, Ng CE, DE Henshall, T Drake, EM Harrison, A Tambyraja, RJE Skipworth, G Linder, R McGregor, J Mayes, R Pasricha, A Razik, S Thrumurthy, D Howden, Z Baxter, L Osagie, M Bence, GE Fowler, N Rajaretnam, A Goubran, JS McGrath, JRA Phillips, DA Raptis, JM Pollok, F Soggiu, S Xyda, C Hidalgo Salinas, H Tzerbinis, T Pissanou, R Mirnezami, N Angamuthu, T Shakir, H Capitelli-McMahon, L Hitchman, A Andronic, A Aboelkassem Ibrahim, J Totty, S Tayeh, T Chase, J Ayorinde, T Cuming, A Trompeter, C Hing, P Tsinaslanidis, MW Benjamin, A Leyte, J Smelt, G Santhirakumaran, A Labib, O Lyons, S Onida, KM Sarraf, S Erridge, S Yalamanchili, A Abuown, D Davenport, S Wheatstone, SM Andreani, MF Bath, A Sahni, L Rigueros Springford, C Sohrabi, J Bacarese-Hamilton, FG Taylor, P Patki, C Tanabalan, ME Alexander, CJ Smart, L Abdeh, M Zeiton, R Advani, S Nikolaou, T Oni, N Ilahi, K Ballantyne, Z Woodward, R Merh, B Robertson-Smith, P Ameerally, JG Finch, C Gnanachandran, I Pop, D Dass, G Thiruchandran, Toh SKC, A Allana, C Bellis, O Babawale, YC Phan, U Lokman, T Koc, L Duggleby, S Shamoon, H Clancy, A Mansuri, A Thakrar, L Wickramarachchi, S Sivayoganathan, E Karam, HV Colvin, A Badran, A Cadersa, A Cumpstey, R Aftab, F Wensley, V Morrison-Jones, GK Sekhon, H Shields, Z Shakoor, T Talbot, A Alzetani, J Rooney, M Rudic, A Aladeojebi, M Kitchen, R Lefroy, P Nanjaiah, AD Rajgor, RJ Scurrah, LJ Watson, T Royle, B Steel, Luk ACO, VG Thiruvasagam, W Marlow, C Konstantinou, D Yershov, A Denning, E Mangos, T Nambirajan, I Flindall, V Mahendran, J De Marchi, NF Davis, A Picciariello, V Papagni, DF Altomare, S Granieri, C Cotsoglou, A Cabeleira, P Serralheiro, T Teles, C Canhoto, J Simões, AC Almeida, O Nogueira, R Athayde Nemésio, MJ Amaral, A Valente da Costa, R Martins, P Guerreiro, A Ruivo, D Breda, JM Oliveira, AL De Oliveira Lopez, M Colino, J De Barros, AP Soares, H Morais, T Revez, MI Manso, JC Domingues, P Henriques, Cardoso N Ribeiro VI, G Martins dos Santos, M Peralta Ferreira, J Ascensão, B Costeira, L Rio Rodrigues, M Sousa Fernandes, P Azevedo, I Lourenço, G Mendinhos, A Nobre Pinto, H Taflin, H Abdou, L O'Meara, Z Cooper, SA Hirji, BU Okafor, V Roxo, CP Raut, JS Jolissaint, DA Mahvi, C Reinke, S Merola, A Ssentongo, P Ssentongo, Oh JS, J Hazelton, J Maines, N Gusani, RCG Martin, N Bhutiani, R Choron, F Soliman, MD E Dauer, E Renza-Stingone, E Gokcen, E Kropf, H Sufrin, J Sewards, J Poggio, K Sanserino, L Rae, M Philp, M Metro, P McNelis, R Petrov, T Pazionis, DB Lumenta, SP Nischwitz, E Richtig, M Pau, P Srekl-Filzmaier, N Eibinger, B Michelitsch, M Fediuk, A Papinutti, TU Cohnert, E Kantor, J Kahiu, S Hosny, A Sultana, M Taggarsi, L Vitone, OP Vaz, I Sarantitis, S Timbrell, A Shugaba, GP Jones, SS Tripathi, MS Greenhalgh, H Emerson, K Vejsbjerg, W McCormick, K Singisetti, Y Aawsaj, R Vanker, M Ghobrial, S Kanthasamy, H Fawi, M Awadallah, J Cheung, S Tingle, F Abbadessa, A Sachdeva, CD Chan, I McPherson, F Mahmoud Ali, S Pandanaboyana, T Grainger, S Nandhra, N Dawe, C McCaffer, J Riches, J Moir, H Elamin Ahmed, C Saleh, RM Koshy, LJ Rogers, PL Labib, N Hope, K Emslie, P Panahi, E Clough, I Enemosah, J Natale, N Raza, JI Webb, M Antar, J Noel, R Nunn, F Eriberto, R Tanna, S Lodhia, C Osório, J Antunes, P Balau, and M Godinho

Subjects
Medicine
Abstract

Objectives Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.Setting Prospective, international, multicentre, observational cohort study.Participants Patients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome 30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.Results This study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).Conclusions Patients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration number NCT04323644

Published
2021
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4. Medical students’ attitudes towards communication skills training: a longitudinal study with one cohort

Author

Ruiz-Moral, Roger, Monge Martin, Diana, Garcia de Leonardo, Cristina, Denizon, Sophia, Cerro Pérez, Alvaro, and Caballero Martínez, Fernando

Subjects
communication skills, experiential learning, longitudinal study, medical education, medical students, Special aspects of education, LC8-6691, Medicine
Abstract

Objectives: To explore medical students’ attitudes towards communication skills and the evolution of these attitudes from their first to fourth academic years. Methods: A cohort of 91 medical students completed the Communication Skills Attitudes Scale (CSAS) at the beginning of their medical studies and at the end of their fourth year after having engaged in a training program in communication skills with experiential characteristics (individual encounters with simulated patients, observations in small groups, feedback, and practice). We analyzed students’ positive and negative global attitudes and their affective, cognitive, and respect dimensions towards learning communication skills.Results: Medical students’ attitudes toward communication skills declined from their first (52.8) to fourth year (49.6) (p=.011). Along with this significant decrease in positive attitudes, a significant increase in negative attitudes toward communication skills was also observed in trained students (32.2 vs. 34.2; p=.023). The decline in students’ attitudes mainly involves a decline in their affective (51.4 vs. 47.3, p=.001) but not cognitive (18.3) attitudes. Female students have more positive attitudes towards communication skills than male students. Conclusions: The decline in students’ attitudes, mainly in the affective dimension, could be related to their accumulated learning experiences during the learning process and particularly their experiential training in communication skills. Nevertheless, the importance students give to communication skills in the cognitive dimension remains unchanged. Students’ gender also seems to influence their attitudes. Further research is needed to assess the role of other factors involved in this decrease in positive and affective attitudes.

Published
2021
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5. The association between dietary fiber intake and gastric cancer: a pooled analysis of 11 case-control studies.

Author

Collatuzzo, Giulia, Cortez Lainez, Jacqueline, Pelucchi, Claudio, Negri, Eva, Bonzi, Rossella, Palli, Domenico, Ferraroni, Monica, Zhang, Zuofeng, Yu, Guo-Pei, Lunet, Nuno, Morais, Samantha, López-Carrillo, Lizbeth, Zaridze, David, Maximovitch, Dmitry, Guevara, Marcela, Santos-Sanchez, Vanessa, Vioque, Jesus, Garcia de la Hera, Manoli, Ward, Mary, Malekzadeh, Reza, Pakseresht, Mohammadreza, Hernández-Ramírez, Raúl, Turati, Federica, Rabkin, Charles, Liao, Linda, Sinha, Rashmi, López-Cervantes, Malaquias, Tsugane, Shoichiro, Hidaka, Akihisa, Camargo, M, Curado, Maria, Zubair, Nadia, Kristjansson, Dana, Shah, Shailja, La Vecchia, Carlo, and Boffetta, Paolo

Subjects
Cardia, Dietary fiber, Fiber intake, Gastric cancer, Gastric neoplasm, Non-cardia, Aged, Female, Humans, Male, Middle Aged, Case-Control Studies, Diet, Dietary Fiber, Fruit, Logistic Models, Odds Ratio, Risk Factors, Stomach Neoplasms, Surveys and Questionnaires, Vegetables
Abstract

PURPOSE: Gastric cancer (GC) is among the leading causes of cancer mortality worldwide. The objective of this study was to investigate the association between dietary fiber intake and GC. METHODS: We pooled data from 11 population or hospital-based case-control studies included in the Stomach Cancer Pooling (StoP) Project, for a total of 4865 histologically confirmed cases and 10,626 controls. Intake of dietary fibers and other dietary factors was collected using food frequency questionnaires. We calculated the odds ratios (OR) and 95% confidence intervals (CI) of the association between dietary fiber intake and GC by using a multivariable logistic regression model adjusted for study site, sex, age, caloric intake, smoking, fruit and vegetable intake, and socioeconomic status. We conducted stratified analyses by these factors, as well as GC anatomical site and histological type. RESULTS: The OR of GC for an increase of one quartile of fiber intake was 0.91 (95% CI: 0.85, 0.97), that for the highest compared to the lowest quartile of dietary fiber intake was 0.72 (95% CI: 0.59, 0.88). Results were similar irrespective of anatomical site and histological type. CONCLUSION: Our analysis supports the hypothesis that dietary fiber intake may exert a protective effect on GC.

Published
2024

6. What explains the success of cross-modal fine-tuning with ORCA?

Author

García-de-Herreros, Paloma, Gautam, Vagrant, Slusallek, Philipp, Klakow, Dietrich, and Mosbach, Marius

Subjects
Computer Science - Computation and Language, Computer Science - Artificial Intelligence, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning
Abstract

ORCA (Shen et al., 2023) is a recent technique for cross-modal fine-tuning, i.e., applying pre-trained transformer models to modalities beyond their training data. The technique consists primarily of training an embedder and fine-tuning the embedder and model. Despite its high performance on a variety of downstream tasks, we do not understand precisely how each of these components contribute to ORCA's success. Therefore, we run a series of ablations and find that embedder training does not help 2D tasks at all, contrary to what the original paper posits. In 1D tasks, some amount of embedder training is necessary but more is not better. In 4 out of 6 datasets we experiment with, it is model fine-tuning that makes the biggest difference. Through our ablations and baselines, we contribute a better understanding of the individual components of ORCA.

Published
2024

10. Prevention of HIV and Other Sexually Transmitted Infections by Geofencing and Contextualized Messages With a Gamified App, UBESAFE: Design and Creation Study

Author

Besoain, Felipe, Perez-Navarro, Antoni, Jacques Aviñó, Constanza, Caylà, Joan A, Barriga, Nicolas A, and Garcia de Olalla, Patricia

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundAdvances in the development of information and communication technologies have facilitated social and sexual interrelationships, thanks to the websites and apps created to this end. However, these resources can also encourage sexual contacts without appropriate preventive measures in relation to HIV and other sexually transmitted infections (STIs). How can users be helped to benefit from the advantages of these apps while keeping in mind those preventive measures? ObjectiveThis study aimed to prevent STIs by helping users to remember preventive measures in the risky situations. MethodsWe have used the design and creation methodology and have developed a software system. This system has two parts: an Android operating system app with emphasis on ubiquitous computing and gamification as well as a server with a webpage. First, a functional test with 5 men who have sex with men (MSM) allowed us to test the app with end users. In addition, a feasibility test with 4 MSM for a month allowed us to try the UBESAFE system with all its functionalities. ResultsThe main output is a system called UBESAFE that is addressed to MSM. The system has two main parts: (1) an app that sends preventive contextualized messages to users when they use a contact app or when they are near a point where sexual contacts are likely and (2) a server part that was managed by the public health agency of Barcelona (ASPB), which preserves the quality and pertinence of messages and places and offers instant help to users. To increase users’ adherence, UBESAFE uses a gamified system to engage users in the creation of preventive messages. Users increased the initial pool of messages by more than 100% (34/30) and created more than 56% (9/16) of places (named hot zones). ConclusionsThe system helped MSM who used it to become conscious about HIV and other STIs. The system also helped the ASPB to stay in contact with MSM and to detect behaviors that could benefit from preventive measures. All functions were performed in a nonintrusive manner because users used the app privately. Furthermore, the system has shown how important it is to make users a part of the creation process as well as to develop apps that work by themselves and thus become useful to the users.

Published
2020
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11. Novel IMU-based Adaptive Estimator of the Center of Rotation of Joints for Movement Analysis

Author

García-de-Villa, Sara, Jiménez-Martín, Ana, and García-Domínguez, J. Jesús

Subjects
Electrical Engineering and Systems Science - Signal Processing, J.2
Abstract

The location of the center of rotation (COR) of joints is a key parameter in multiple applications of human motion analysis. The aim of this work was to propose a novel real-time estimator of the center of fixed joints using an inertial measurement unit (IMU). Since the distance to this center commonly varies during the joint motion due to soft tissue artifacts (STA), our approach is aimed at adapting to these small variations when the COR is fixed. Our proposal, called ArVEd, to the best of our knowledge, is the first real-time estimator of the IMU-joint center vector based on one IMU. Previous works are off-line and require a complete measurement batch to be solved and most of them are not tested on the real scenario. The algorithm is based on an Extended Kalman Filter (EKF) that provides an adaptive vector to STA motion variations at each time instant, without requiring a pre-processing stage to reduce the level of noise. ArVEd has been tested through different experiments, including synthetic and real data. The synthetic data are obtained from a simulated spherical pendulum whose COR is fixed, considering both a constant and a variable IMU-joint vector, that simulates translational IMU motions due to STA. The results prove that ArVEd is adapted to obtain a vector per sample with an accuracy of 6.8$\pm$3.9 on the synthetic data, that means an error lower than 3.5% of the simulated IMU-joint vector. Its accuracy is also tested on the real scenario estimating the COR of the hip of 5 volunteers using as reference the results from an optical system. In this case, ArVEd gets an average error of 9.5% of the real vector value. In all the experiments, ArVEd outperforms the published results of the reference algorithms., Comment: \c{opyright} 2021 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works

Published
2024
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12. SAT-CEP-monitor: An air quality monitoring software architecture combining complex event processing with satellite remote sensing

Author

Semlali, Badr-Eddine Boudriki, Amrani, Chaker El, Ortiz, Guadalupe, Boubeta-Puig, Juan, and Garcia-de-Prado, Alfonso

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing, Computer Science - Software Engineering, Electrical Engineering and Systems Science - Signal Processing
Abstract

Air pollution is a major problem today that causes serious damage to human health. Urban areas are the most affected by the degradation of air quality caused by anthropogenic gas emissions. Although there are multiple proposals for air quality monitoring, in most cases, two limitations are imposed: the impossibility of processing data in Near Real-Time (NRT) for remote sensing approaches and the impossibility of reaching areas of limited accessibility or low network coverage for ground data approaches. We propose a software architecture that efficiently combines complex event processing with remote sensing data from various satellite sensors to monitor air quality in NRT, giving support to decision-makers. We illustrate the proposed solution by calculating the air quality levels for several areas of Morocco and Spain, extracting and processing satellite information in NRT. This study also validates the air quality measured by ground stations and satellite sensor data.

Published
2024
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13. Improving device-aware Web services and their mobile clients through an aspect-oriented, model-driven approach

Author

Ortiz, Guadalupe and Garcia-de-Prado, Alfonso

Subjects
Computer Science - Software Engineering
Abstract

Context: Mobile devices have become an essential element in our daily lives, even for connecting to the Internet. Consequently, Web services have become extremely important when offering services through the Internet. However, current Web services are very inflexible as regards their invocation from different types of device, especially if we consider the need for them to be adaptable when being invoked from mobile devices. Objective: In this paper, we provide an approach for the creation of flexible Web services which can be invoked transparently from different device types and which return subsequent responses, as well as providing the client's adaptation as a result of the particular device characteristics and end-user preferences in a completely decoupled way. Method: Aspect-Oriented Programming and model-driven development have been used to reduce both the impact of service and client code adaptation for multiple devices as well as to facilitate the developer's task. Results: A model-driven methodology can be followed from system models to code, providing the Web service developer with the option of marking which services should be adapted to mobile devices in the UML models, and obtaining the decoupled adaptation code automatically from the models. Conclusion: We can conclude that the approach presented in this paper provides us with the possibility of following the development of mobile-aware Web services in an integrated platform, benefiting from the use of aspect-oriented techniques not only for maintaining device-related code completely decoupled from the main functionality one, but also allowing a modularized non-intrusive adaptation of mobile clients to the specific device characteristics as well as to final user preferences.

Published
2024
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14. A microservice architecture for real-time IoT data processing: A reusable Web of things approach for smart ports

Author

Ortiz, Guadalupe, Boubeta-Puig, Juan, Criado, Javier, Corral-Plaza, David, Garcia-de-Prado, Alfonso, Medina-Bulo, Inmaculada, and Iribarne, Luis

Subjects
Computer Science - Software Engineering, Computer Science - Artificial Intelligence
Abstract

Major advances in telecommunications and the Internet of Things have given rise to numerous smart city scenarios in which smart services are provided. What was once a dream for the future has now become reality. However, the need to provide these smart services quickly, efficiently, in an interoperable manner and in real time is a cutting-edge technological challenge. Although some software architectures offer solutions in this area, these are often limited in terms of reusability and maintenance by independent modules, involving the need for system downtime when maintaining or evolving, as well as by a lack of standards in terms of the interoperability of their interface. In this paper, we propose a fully reusable microservice architecture, standardized through the use of the Web of things paradigm, and with high efficiency in real-time data processing, supported by complex event processing techniques. To illustrate the proposal, we present a fully reusable implementation of the microservices necessary for the deployment of the architecture in the field of air quality monitoring and alerting in smart ports. The performance evaluation of this architecture shows excellent results.

Published
2024
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15. Atmosphere: Context and situational-aware collaborative IoT architecture for edge-fog-cloud computing

Author

Ortiz, Guadalupe, Zouai, Meftah, Kazar, Okba, Garcia-de-Prado, Alfonso, and Boubeta-Puig, Juan

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing, Computer Science - Artificial Intelligence, Computer Science - Software Engineering
Abstract

The Internet of Things (IoT) has grown significantly in popularity, accompanied by increased capacity and lower cost of communications, and overwhelming development of technologies. At the same time, big data and real-time data analysis have taken on great importance and have been accompanied by unprecedented interest in sharing data among citizens, public administrations and other organisms, giving rise to what is known as the Collaborative Internet of Things. This growth in data and infrastructure must be accompanied by a software architecture that allows its exploitation. Although there are various proposals focused on the exploitation of the IoT at edge, fog and/or cloud levels, it is not easy to find a software solution that exploits the three tiers together, taking maximum advantage not only of the analysis of contextual and situational data at each tier, but also of two-way communications between adjacent ones. In this paper, we propose an architecture that solves these deficiencies by proposing novel technologies which are appropriate for managing the resources of each tier: edge, fog and cloud. In addition, the fact that two-way communications along the three tiers of the architecture is allowed considerably enriches the contextual and situational information in each layer, and substantially assists decision making in real time. The paper illustrates the proposed software architecture through a case study of respiratory disease surveillance in hospitals. As a result, the proposed architecture permits efficient communications between the different tiers responding to the needs of these types of IoT scenarios.

Published
2024
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16. Inertial Sensors for Human Motion Analysis: A Comprehensive Review

Author

García-de-Villa, Sara, Casillas-Pérez, David, Jiménez-Martín, Ana, and García-Domínguez, Juan Jesús

Subjects
Electrical Engineering and Systems Science - Systems and Control, A.1
Abstract

Inertial motion analysis is having a growing interest during the last decades due to its advantages over classical optical systems. The technological solution based on inertial measurement units allows the measurement of movements in daily living environments, such as in everyday life, which is key for a realistic assessment and understanding of movements. This is why research in this field is still developing and different approaches are proposed. This presents a systematic review of the different proposals for inertial motion analysis found in the literature. The search strategy has been carried out on eight different platforms, including journal articles and conference proceedings, which are written in English and published until August 2022. The results are analyzed in terms of the publishers, the sensors used, the applications, the monitored units, the algorithms of use, the participants of the studies, and the validation systems employed. In addition, we delve deeply into the machine learning techniques proposed in recent years and in the approaches to reduce the estimation error. In this way, we show an overview of the research carried out in this field, going into more detail in recent years, and providing some research directions for future work

Published
2024
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17. A database of physical therapy exercises with variability of execution collected by wearable sensors

Author

García-de-Villa, Sara, Jiménez-Martín, Ana, and García-Domínguez, Juan Jesús

Subjects
Electrical Engineering and Systems Science - Signal Processing, E.5
Abstract

This document introduces the PHYTMO database, which contains data from physical therapies recorded with inertial sensors, including information from an optical reference system. PHYTMO includes the recording of 30 volunteers, aged between 20 and 70 years old. A total amount of 6 exercises and 3 gait variations were recorded. The volunteers performed two series with a minimum of 8 repetitions in each one. PHYTMO includes magneto-inertial data, together with a highly accurate location and orientation in the 3D space provided by the optical system. The files were stored in CSV format to ensure its usability. The aim of this dataset is the availability of data for two main purposes: the analysis of techniques for the identification and evaluation of exercises using inertial sensors and the validation of inertial sensor-based algorithms for human motion monitoring. Furthermore, the database stores enough data to apply Machine Learning-based algorithms. The participants' age range is large enough to establish age-based metrics for the exercises evaluation or the study of differences in motions between different groups.

Published
2024
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18. Simultaneous exercise recognition and evaluation in prescribed routines: Approach to virtual coaches

Author

García-de-Villa, Sara, Casillas-Pérez, David, Jiménez-Martín, Ana, and García-Domínguez, Juan Jesús

Subjects
Computer Science - Human-Computer Interaction, Electrical Engineering and Systems Science - Signal Processing, I.2.1
Abstract

Home-based physical therapies are effective if the prescribed exercises are correctly executed and patients adhere to these routines. This is specially important for older adults who can easily forget the guidelines from therapists. Inertial Measurement Units (IMUs) are commonly used for tracking exercise execution giving information of patients' motion data. In this work, we propose the use of Machine Learning techniques to recognize which exercise is being carried out and to assess if the recognized exercise is properly executed by using data from four IMUs placed on the person limbs. To the best of our knowledge, both tasks have never been addressed together as a unique complex task before. However, their combination is needed for the complete characterization of the performance of physical therapies. We evaluate the performance of six machine learning classifiers in three contexts: recognition and evaluation in a single classifier, recognition of correct exercises, excluding the wrongly performed exercises, and a two-stage approach that first recognizes the exercise and then evaluates it. We apply our proposal to a set of 8 exercises of the upper-and lower-limbs designed for maintaining elderly people health status. To do so, the motion of volunteers were monitored with 4 IMUs. We obtain accuracies of 88.4 \% and the 91.4 \% in the two initial scenarios. In the third one, the recognition provides an accuracy of 96.2 \%, whereas the exercise evaluation varies between 93.6 \% and 100.0 \%. This work proves the feasibility of IMUs for a complete monitoring of physical therapies in which we can get information of which exercise is being performed and its quality, as a basis for designing virtual coaches.

Published
2024
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19. Nye perspektiv på Hans Nielsen Hauge

Author

Farstad, Eli Morken, Nymark, Kristian Holen, Bugge Amundsen, Arne, Garcia de Presno, Jostein, Gilje, Nils, Langhelle, Svein Ivar, Norseth, Kristin, Roos, Merethe, Kringlebotn Sødal, Helje, Farstad, Eli M., and Nymark, Kristian H.

Subjects
Hans Nielsen Hauge, Haugean movement, religiosity, social movement, political mobilization, Hans Nielsen Hauge, Hauge-bevegelsen, religiøsitet, folkebevegelse, politisk mobilisering, bic Book Industry Communication::H Humanities::HR Religion & beliefs, bic Book Industry Communication::H Humanities::HR Religion & beliefs::HRC Christianity, bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFS Social groups::JFSR Religious groups: social & cultural aspects
Abstract

Hans Nielsen Hauge established and led at the end of the 18th century Norway's first nationwide popular movement, a low church network that would leave its mark on everyday life, business development and politics in the transition from absolute monarchy to representational government. People called themselves Haugians long after Hauge's death in 1824. It was a spiritual awakening on a scale that deserves considerable room when we write the history of modern Norway. This book provides a new perspective on the roots of the Hauge movement in the religious mentality of the 18th century, on how it functioned in its most radical phase up to 1814, and on the importance of the network for economic modernization and political mobilization in the subsequent decades. Retrospective interpretations of Hauge's complex endeavor are also explored. In sum, the nine chapters provide a broader understanding of the Hauge movement and the era in which it flourished. We hope that the book also sheds light on the state of Norway's people, government and religiosity today, over 250 years after Hauge's birth. The book has been edited by research fellow Eli Morken Farstad and associate professor Kristian Holen Nymark, both historians at the University of South-Eastern Norway., Hans Nielsen Hauge startet Norges første landsomfattende folkebevegelse på slutten av 1700-tallet. Det lavkirkelige nettverket satte sitt preg på hverdagsliv, næringsutvikling og politikk i overgangen fra enevelde til folkestyre. Folk kalte seg haugianere lenge etter Hauges død i 1824. En slik vekkelse må få stor plass når vi skriver historien om det moderne Norge. Denne boka gir nye perspektiv på Hauge-bevegelsens røtter i 1700-tallets religiøse mentalitet, på hvordan vekkelsen virket i sin mest radikale fase fram mot 1814, og på nettverkets betydning for økonomisk modernisering og politisk mobilisering framover i hundreåret. Ettertidens fortolkning av Hauges mangslungne virksomhet blir også lagt under lupen. I sum gir de ni kapitlene en bredere forståelse av Hauge-bevegelsen og tiden den virket i. Vi håper at boka også kan kaste lys over folk, stat og religiøsitet i dag, over 250 år etter Hauges fødsel. Boka er redigert av stipendiat Eli Morken Farstad og førsteamanuensis Kristian Holen Nymark, begge historikere ved Universitetet i Sørøst-Norge.

Published
2023
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22. Inland navigation and land use interact to impact European freshwater biodiversity

Author

Sexton, Aaron N., Beisel, Jean-Nicolas, Staentzel, Cybill, Wolter, Christian, Tales, Evelyne, Belliard, Jérôme, Buijse, Anthonie D., Martínez Fernández, Vanesa, Wantzen, Karl M., Jähnig, Sonja C., Garcia de Leaniz, Carlos, Schmidt-Kloiber, Astrid, Haase, Peter, Forio, Marie Anne Eurie, Archambaud, Gait, Fruget, Jean-François, Dohet, Alain, Evtimova, Vesela, Csabai, Zoltán, Floury, Mathieu, Goethals, Peter, Várbiró, Gábor, Cañedo-Argüelles, Miguel, Larrañaga, Aitor, Maire, Anthony, Schäfer, Ralf B., Sinclair, James S., Vannevel, Rudy, Welti, Ellen A. R., and Jeliazkov, Alienor

Published
2024
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24. First record of Triops gadensis Korn and García-de-Lomas, 2010 (Crustacea: Notostraca) in Córdoba Province, southern Spain

Author

López-Martínez, Mónica, Garcia-De-Lomas, Juan, Marrone, Federico, Vecchioni, Luca, Faraone, Francesco Paolo, and Korn, Michael

Subjects
Mediterranean temporary ponds, Guadalcázar, La Dehesilla, Pleurodeles waltl, Pelodytes ibericus, molecular clock
Abstract

We studied a Triops population from a Mediterranean temporary pond located in Guadalcázar, a township in the western part of Córdoba Province. There are four morphologically similar species of Triops occurring in the SW Iberian Peninsula. In particular, the two species found in southern Andalusia, T. baeticus and T. gadensis, cannot reliably be told apart based on known morphological characters. We thus used sequences of 12S rDNA as a molecular marker to soundly identify the population to species rank. Our results demonstrate that the Triops population studied belongs to T. gadensis. This result is rather unexpected given that the species was thought to be restricted to a small distribution range along the Atlantic coast in Cádiz Province. The population is located at approximately 170 km from previously known sites of T. gadensis and shows a previously unknown haplotype, the sixth 12S haplotype reported for the species. Based on a molecular clock designed for dating divergence events among conspecific samples of Triops, the haplotype is estimated to have diverged at 10.3–29.4 ka BP. We thus suggest that the population has high conservation value, and its habitat, including the surroundings, should be legally protected. We further propose that an open habitat type as pastureland should be retained for the surroundings of the site in order to support its ecological function in the frame of meta-populations dynamics, and as a possible source population from which new localities could be populated via passive dispersal.

Published
2024

26. Serious Video Games for Agricultural Learning: Scoping Review

Author

Ismael E. Espinosa-Curiel and Carlos A. Garcia de Alba-Chavez

Abstract

Serious video games provide a immersive learning environment for agriculture by simulating real-life challenges scenarios. However, empirical evidence of their effectiveness is sparse. This scoping review follows PRISMA-ScR guidelines to summarize literature on serious video games for agricultural learning, highlighting research trends and identifying gaps. We systematically searched nine prominent research databases for papers on serious video games for agriculture learning published between January 2000 and July 2022. Two independent reviewers conducted screening, data extraction, and synthesized the collected data using a narrative approach. The initial search identified 3,297 articles, of which 0.58% (n = 19) were included in the review. Most reviewed games were released in the last five years, with a predominant presence in the mobile platform. They commonly employed a simulation-based approach, featuring 2-D graphics and designed for single-player experiences. These games mainly target students, focusing on crop production and sustainable agriculture. Educational theories were often unspecified in the studies. Evaluation protocols primarily consisted of pilot studies, emphasizing user experience and knowledge enhancement. Positive outcomes, such as improved user experiences, knowledge, and attitude and behavior changes, were commonly observed in these studies. This study highlights advancements in using serious video games for agricultural learning over 20 years. However, it stresses the need for deeper exploration of game elements' impact on user experience and effectiveness. Creating games for underrepresented players and specific agricultural challenges is essential, as is enhancing theoretical foundations and learning approaches. Rigorous research designs are vital for assessing game effectiveness across short, medium, and long terms.

Published
2024
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28. Photonic counterdiabatic quantum optimization algorithm

Author

Chandarana, Pranav, Paul, Koushik, Garcia-de-Andoin, Mikel, Ban, Yue, Sanz, Mikel, and Chen, Xi

Subjects
Quantum Physics, Physics - Optics
Abstract

We propose a hybrid quantum-classical approximate optimization algorithm for photonic quantum computing, specifically tailored for addressing continuous-variable optimization problems. Inspired by counterdiabatic protocols, our algorithm significantly reduces the required quantum operations for optimization as compared to adiabatic protocols. This reduction enables us to tackle non-convex continuous optimization and countably infinite integer programming within the near-term era of quantum computing. Through comprehensive benchmarking, we demonstrate that our approach outperforms existing state-of-the-art hybrid adiabatic quantum algorithms in terms of convergence and implementability. Remarkably, our algorithm offers a practical and accessible experimental realization, bypassing the need for high-order operations and overcoming experimental constraints. We conduct proof-of-principle experiments on an eight-mode nanophotonic quantum chip, successfully showcasing the feasibility and potential impact of the algorithm.

Published
2023
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29. Digital-Analog Quantum Computation with Arbitrary Two-Body Hamiltonians

Author

Garcia-de-Andoin, Mikel, Saiz, Álvaro, Pérez-Fernández, Pedro, Lamata, Lucas, Oregi, Izaskun, and Sanz, Mikel

Subjects
Quantum Physics
Abstract

Digital-analog quantum computing is a computational paradigm which employs an analog Hamiltonian resource together with single-qubit gates to reach universality. Here, we design a new scheme which employs an arbitrary two-body source Hamiltonian, extending the experimental applicability of this computational paradigm to most quantum platforms. We show that the simulation of an arbitrary two-body target Hamiltonian of $n$ qubits requires $\mathcal{O}(n^2)$ analog blocks with guaranteed positive times, providing a polynomial advantage compared to the previous scheme. Additionally, we propose a classical strategy which combines a Bayesian optimization with a gradient descent method, improving the performance by $\sim55\%$ for small systems measured in the Frobenius norm., Comment: Updated with extended numerical experiments

Published
2023
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33. The Global Dam Watch database of river barrier and reservoir information for large-scale applications

Author

Lehner, Bernhard, Beames, Penny, Mulligan, Mark, Zarfl, Christiane, De Felice, Luca, van Soesbergen, Arnout, Thieme, Michele, Garcia de Leaniz, Carlos, Anand, Mira, Belletti, Barbara, Brauman, Kate A., Januchowski-Hartley, Stephanie R., Lyon, Kimberly, Mandle, Lisa, Mazany-Wright, Nick, Messager, Mathis L., Pavelsky, Tamlin, Pekel, Jean-François, Wang, Jida, Wen, Qingke, Wishart, Marcus, Xing, Tianqi, Yang, Xiao, and Higgins, Jonathan

Published
2024
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36. Real-world multidisciplinary outcomes of onasemnogene abeparvovec monotherapy in patients with spinal muscular atrophy type 1: experience of the French cohort in the first three years of treatment

Author

Desguerre, Isabelle, Barrois, Rémi, Audic, Frédérique, Barnerias, Christine, Chabrol, Brigitte, Davion, Jean Baptiste, Durigneux, Julien, Espil-Taris, Caroline, Gomez-Garcia de la Banda, Marta, Guichard, Marine, Isapof, Arnaud, Nougues, Marie Christine, Laugel, Vincent, Le Goff, Laure, Mercier, Sandra, Pervillé, Anne, Richelme, Christian, Thibaud, Marie, Sarret, Catherine, Schweitzer, Cyril, Testard, Hervé, Trommsdorff, Valérie, Vanhulle, Catherine, Walther-Louvier, Ulrike, Altuzarra, Cécilia, Chouchane, Mondher, Ropars, Juliette, Quijano-Roy, Susana, and Cances, Claude

Published
2024
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39. Long-term surveillance of SARS-CoV-2 in the school community from Campo Grande, Brazil

Author

Alcantara, Daniel Maximo Correa, dos Santos, Camila Maria, Torres, Jaire Marinho, Stutz, Claudia, Vieira, Camila Aoyama, Moreira, Raissa Mariele dos Santos, Rodrigues, Rudielle, Marcon, Glaucia Elisete Barbosa, Ferreira, Eduardo de Castro, Mendes, Flavia Maria Lins, Sarti, Elaine Cristina Fernandes Baez, de Oliveira, Thiago Fernandes, Lemos, Everton Ferreira, Andrade, Ursulla Vilella, Lichs, Gislene Garcia de Castro, Demarchi, Luiz Henrique Ferraz, Zardin, Marina Castilhos Souza Umaki, Gonçalves, Crhistinne Cavalheiro Maymone, Guilhermino, Jislaine de Fátima, and Fernandez, Zoraida del Carmen

Published
2024
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42. Plastic pigtail vs lumen-apposing metal stents for drainage of walled-off necrosis (PROMETHEUS study): an open-label, multicenter randomized trial

Author

Gornals, Joan B., Velasquez-Rodriguez, Julio G., Bas-Cutrina, Francesc, Garcia Garcia De Paredes, Ana, Esteban, Jose-Miguel, Teran, Alvaro, Gonzalez-Huix, Ferran, Perez-Miranda, Manuel, Guarner-Argente, Carlos, Vila, Juan J., Garcia-Sumalla, Albert, Foruny, Jose Ramon, Fisac-Vazquez, Joaquin, Moris, Maria, Miquel-Salas, Isabel, De-la-Serna Higuera, Carlos, Murzi-Pulgar, Marianette, Sanchez-Yague, Andres, Salord, Silvia, Ruiz-Osuna, Sandra, Busquets, Juli, Sanllorente-Melenchon, Mireia, Videla, Sebas, Moreno, Ramon, Tebe-Cordomi, Cristian, Hereu, Pilar, and Vazquez-Sequeiros, Enrique

Published
2024
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43. Membrane Phenotypic, Metabolic and Genotypic Adaptations of Streptococcus oralis Strains Destined to Rapidly Develop Stable, High-Level Daptomycin Resistance during Daptomycin Exposures.

Author

de Paula Baptista, Rodrigo, Tran, Truc, Lapitan, Christian, Garcia-de-la-Maria, Cristina, Miró, Jose, Proctor, Richard, Bayer, Arnold, and Mishra, Nagendra

Subjects
S. oralis, glycolysis, high-level daptomycin resistance, lipids
Abstract

The Streptococcus mitis-oralis subgroup of viridans group streptococci are important human pathogens. We previously showed that a substantial portion of S. mitis-oralis strains (>25%) are destined to develop rapid, high-level, and stable daptomycin (DAP) resistance (DAP-R) during DAP exposures in vitro. Such DAP-R is often accompanied by perturbations in distinct membrane phenotypes and metabolic pathways. The current study evaluated two S. oralis bloodstream isolates, 73 and 205. Strain 73 developed stable, high-level DAP-R (minimum inhibitory concentration [MIC] > 256 µg/mL) within 2 days of in vitro DAP passage (high level DAP-R [HLDR]). In contrast, strain 205 evolved low-level and unstable DAP-R (MIC = 8 µg/mL) under the same exposure conditions in vitro (non-HLDR). Comparing the parental 73 vs. 73-D2 (HLDR) strain-pair, we observed the 73-D2 had the following major differences: (i) altered cell membrane (CM) phospholipid profiles, featuring the disappearance of phosphatidylglycerol (PG) and cardiolipin (CL), with accumulation of the PG-CL pathway precursor, phosphatidic acid (PA); (ii) enhanced CM fluidity; (iii) increased DAP surface binding; (iv) reduced growth rates; (v) decreased glucose utilization and lactate accumulation; and (vi) increased enzymatic activity within the glycolytic (i.e., lactate dehydrogenase [LDH]) and lipid biosynthetic (glycerol-3-phosphate dehydrogenase [GPDH]) pathways. In contrast, the 205 (non-HLDR) strain-pair did not show these same phenotypic or metabolic changes over the 2-day DAP exposure. WGS analyses confirmed the presence of mutations in genes involved in the above glycolytic and phospholipid biosynthetic pathways in the 73-D2 passage variant. These data suggest that S. oralis strains which are destined to rapidly develop HLDR do so via a conserved cadre of genotypic, membrane phenotypic, and metabolic adaptations.

Published
2023

45. INCIDÊNCIA DE CÂNCER EM PESSOAS COM SÍNDROME DE DOWN: UM ESTUDO BIBLIOMÉTRICO

Author

Cunha, Tamirys Franco, primary, Silva, Aline Oliveira da Costa e, additional, Sampaio, Carlos Peres, additional, Pinheiro, Ana Paula Brito, additional, Mello, Lucas Rodrigo Garcia de, additional, Marins, Ana Lucia Cascardo, additional, Santos, Renata Oliveira Maciel dos, additional, Franco, Andrezza Serpa, additional, Paula, Vanessa Galdino de, additional, Neto, Nereu Gilberto de Moraes Guerra, additional, and Andrade, Karla Biancha Silva de, additional

Published
2024
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46. REPERCUSSÕES DO CÂNCER INFANTOJUVENIL: UMA REVISÃO INTEGRATIVA

Author

Abreu, Laura Raquel Soares de, primary, Pinheiro, Ana Paula Brito, additional, Soares, Samira Silva Santos, additional, Mello, Lucas Rodrigo Garcia de, additional, Lisboa, Caroline de Deus, additional, Mazzoni, Vivian Gomes, additional, Henrique, Danielle de Mendonça, additional, Tomaz, Ana Paula kelly de Almeida, additional, and Andrade, Karla Biancha Silva de, additional

Published
2024
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47. OCUPAÇÃO DE LEITOS DE TERAPIA INTENSIVA NA PANDEMIA DA COVID-19: PERSPECTIVAS GERENCIAIS DA ENFERMAGEM ONCOLÓGICA

Author

Mazzoni, Vivian Gomes, primary, Marcellini, Paulo Sergio, additional, Carvalho, Eloá Carneiro, additional, Muzi, Camila Drumond, additional, Mello, Lucas Rodrigo Garcia de, additional, Marins, Ana Lucia Cascardo, additional, Carvalho, Ana Fátima Coelho, additional, Mesquita, Ayla Maria Farias de, additional, Stipp, Marluci Andrade Conceição, additional, and Andrade, Karla Biancha Silva de, additional

Published
2024
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48. OSTEOPOROSE NO IDOSO

Author

LUCIANO MARTINS DA SILVA JUNIOR, CICERO, primary, REIS OLEJ, GABRIEL, additional, MATOS PARDIM, GABRIELA, additional, ARAÚJO SOUZA, GUILHERME, additional, MAURÍCIO DA SILVEIRA, HENRIQUE, additional, PEDRO ALMEIDA WERNECK, JOÃO, additional, FAGUNDES MARTINS, LEONARDO, additional, CAROLINE FIRMINO, LUANA, additional, AMANDA MARTINS PILLAR, MARIA, additional, LÚCIA SOUZA MENDONÇA, MARIA, additional, CIDACO DE OLIVEIRA COUTINHO, MARIANA, additional, MAGGINI SERAPHIM, NICOLI, additional, DONIZETTI MORAES SILVA, RAUL, additional, RODRIGUES GARCIA DE ALMEIDA, VINÍCIUS, additional, and VIEIRA SOARES, DÉBORA, additional

Published
2024
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49. ESTIGMA E ACEITAÇÃO: EXPLORANDO AS DIMENSÕES SOCIAIS DO PÉ TORTO CONGÊNITO NA INFÂNCIA

Author

Oliva, Amanda de Oliveira, primary, Rosa, Pedro Cruz Garcia, additional, Furlan, Jullia Baccar, additional, Bueno, Nayara Souza, additional, Alssuffi, José Eduardo Azero, additional, Figueiredo, Ellen Victória, additional, Castro, Gabrielly Garcia de, additional, Becegatto, Tatiana Ferrari, additional, Silva, Ana Luara Barcelos, additional, Cavalcante, Flavia Roberta Posterli, additional, Criado, Luiza Bottaro, additional, Sampar, Augusto César Aparecido Vitoratto, additional, Soares, Gustavo Mayo, additional, Dall'Agnol, Vitor Toribio, additional, and Netto, Mauricio Lopes da Silva, additional

Published
2024
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