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Your search keyword '"Garcia, Andres J."' showing total 239 results
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239 results on '"Garcia, Andres J."'

3. Recomendaciones sobre el manejo de la obesidad grave en pacientes con enfermedad inflamatoria intestinal del Grupo Español de Trabajo en Enfermedad Inflamatoria Intestinal (GETECCU), Sociedad Española de Obesidad (SEEDO), Asociación Española de Cirugía (AEC) y Sociedad Española de Endoscopia Digestiva (SEED)

Author

Balibrea, José María, Barreiro-de Acosta, Manuel, Butragueño, Javier, Cañete, Fiorella, Ciudin Mihai, Andreea, Crujeiras, Ana B., del Pozo-García, Andrés J., Domènech, Eugeni, Esteban López-Jamar, José Miguel, Espinet-Coll, Eduard, Ferrer-Márquez, Manuel, Flores, Lilliam, Dolores Frutos, M., Gutiérrez, Ana, Hernández-Camba, Alejandro, Mañosa, Míriam, Rodríguez-Moranta, Francisco, Sabench, Fàtima, Turró, Román, Zabana, Yamile, and Ciudin, Andreea

Published
2024
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4. Spanish Intragastric Balloon Consensus Statement (SIBC): practical guidelines based on experience of over 20 000 cases

Author

Coll, Eduardo Espinet, Garcia, Andres J. del Pozo, Arau, Roman Turro, Duran, Javier Nebreda, Rizo, Xavier Cortes, Jimenez, Andres Serrano, Uso, Miguel Angel Escarti, Tornero, Maria Munoz, Martinez, David Carral, Lopez, Jaime Bernabeu, Bernal, Cristian Sierra, Ares, David Martinez, Diez, Jesus Espinel, Valenciano, Carlos Marra-Lopez, Vera, Javier Sola, Artero, Laura Sanchis, Jimenez, Jose Luis Dominguez, Macian, Ramiro Carreno, Fernandez, Jose Francisco Juanmartinena, Zulueta, Arnulfo Fernandez, Alvarado, Claudia Consiglieri, Grecco, Eduardo, Silva, Lyz Bezerra, and Neto, Manoel Galvao

Published
2023
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9. Bioengineered omental transplant site promotes pancreatic islet allografts survival in non-human primates

Author

Deng, Hongping, Zhang, Alexander, Pang, Dillon Ren Rong, Xi, Yinsheng, Yang, Zhihong, Matheson, Rudy, Li, Guoping, Luo, Hao, Lee, Kang M., Fu, Qiang, Zou, Zhongliang, Chen, Tao, Wang, Zhenjuan, Rosales, Ivy A., Peters, Cole W., Yang, Jibing, Coronel, María M., Yolcu, Esma S., Shirwan, Haval, García, Andrés J., Markmann, James F., and Lei, Ji

Published
2023
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24. Main prophylactic measures in bariatric endoscopy. Spanish Expert Recommendations Guideline

Author

Coll, Eduardo Espinet, Arau, Roman Turro, Calzada, Aitor Orive, Abadia, Carlos Dolz, de Gordejuela, Amador Garcia Ruiz, Sanchez-Yague, Andres, Duran, Javier Nebreda, Neto, Manoel Galvao, Beviere, Gontrand Lopez-Nava, Bilbao, Alfredo Mata, Vargas, Alfonso Alcalde, Belando, Ramon Abad, del Pozo-Garcia, Andres J., Lopez-Jamar, Jose Miguel Esteban, Gebelli, Jordi Pujol, Torres Garcia, Antonio Jose, Felipe, Jose Ramirez, and Munoz-Navas, Miguel

Published
2020
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27. Theory and data for simulating fine-scale human movement in an urban environment

Author

Perkins, T Alex, Garcia, Andres J, Paz-Soldán, Valerie A, Stoddard, Steven T, Reiner, Robert C, Vazquez-Prokopec, Gonzalo, Bisanzio, Donal, Morrison, Amy C, Halsey, Eric S, Kochel, Tadeusz J, Smith, David L, Kitron, Uriel, Scott, Thomas W, and Tatem, Andrew J

Subjects
Biological Sciences, Ecology, Good Health and Well Being, Cities, Computer Simulation, Geographic Information Systems, Geographic Mapping, Humans, Interviews as Topic, Models, Theoretical, Motor Activity, Peru, Spatial Behavior, Time Factors, activity space, agent-based model, co-location and contact networks, human mobility, simulation, synthetic population, General Science & Technology
Abstract

Individual-based models of infectious disease transmission depend on accurate quantification of fine-scale patterns of human movement. Existing models of movement either pertain to overly coarse scales, simulate some aspects of movement but not others, or were designed specifically for populations in developed countries. Here, we propose a generalizable framework for simulating the locations that an individual visits, time allocation across those locations, and population-level variation therein. As a case study, we fit alternative models for each of five aspects of movement (number, distance from home and types of locations visited; frequency and duration of visits) to interview data from 157 residents of the city of Iquitos, Peru. Comparison of alternative models showed that location type and distance from home were significant determinants of the locations that individuals visited and how much time they spent there. We also found that for most locations, residents of two neighbourhoods displayed indistinguishable preferences for visiting locations at various distances, despite differing distributions of locations around those neighbourhoods. Finally, simulated patterns of time allocation matched the interview data in a number of ways, suggesting that our framework constitutes a sound basis for simulating fine-scale movement and for investigating factors that influence it.

Published
2014

31. Recasting the theory of mosquito-borne pathogen transmission dynamics and control

Author

Smith, David L, Perkins, T Alex, Reiner, Robert C, Barker, Christopher M, Niu, Tianchan, Chaves, Luis Fernando, Ellis, Alicia M, George, Dylan B, Le Menach, Arnaud, Pulliam, Juliet RC, Bisanzio, Donal, Buckee, Caroline, Chiyaka, Christinah, Cummings, Derek AT, Garcia, Andres J, Gatton, Michelle L, Gething, Peter W, Hartley, David M, Johnston, Geoffrey, Klein, Eili Y, Michael, Edwin, Lloyd, Alun L, Pigott, David M, Reisen, William K, Ruktanonchai, Nick, Singh, Brajendra K, Stoller, Jeremy, Tatem, Andrew J, Kitron, Uriel, Godfray, H Charles J, Cohen, Justin M, Hay, Simon I, and Scott, Thomas W

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Vector-Borne Diseases, Infectious Diseases, Rare Diseases, Infection, Good Health and Well Being, Animals, Culicidae, Humans, Insect Vectors, Models, Biological, Models, Theoretical, Parasitic Diseases, Dengue, Filariasis, Malaria, Mosquito-borne pathogen transmission, Vector control, West Nile virus, Microbiology, Public Health and Health Services, Tropical Medicine, Clinical sciences, Medical microbiology, Epidemiology
Abstract

Mosquito-borne diseases pose some of the greatest challenges in public health, especially in tropical and sub-tropical regions of the world. Efforts to control these diseases have been underpinned by a theoretical framework developed for malaria by Ross and Macdonald, including models, metrics for measuring transmission, and theory of control that identifies key vulnerabilities in the transmission cycle. That framework, especially Macdonald's formula for R0 and its entomological derivative, vectorial capacity, are now used to study dynamics and design interventions for many mosquito-borne diseases. A systematic review of 388 models published between 1970 and 2010 found that the vast majority adopted the Ross-Macdonald assumption of homogeneous transmission in a well-mixed population. Studies comparing models and data question these assumptions and point to the capacity to model heterogeneous, focal transmission as the most important but relatively unexplored component in current theory. Fine-scale heterogeneity causes transmission dynamics to be nonlinear, and poses problems for modeling, epidemiology and measurement. Novel mathematical approaches show how heterogeneity arises from the biology and the landscape on which the processes of mosquito biting and pathogen transmission unfold. Emerging theory focuses attention on the ecological and social context for mosquito blood feeding, the movement of both hosts and mosquitoes, and the relevant spatial scales for measuring transmission and for modeling dynamics and control.

Published
2014

35. A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970–2010

Author

Reiner, Robert C, Perkins, T Alex, Barker, Christopher M, Niu, Tianchan, Chaves, Luis Fernando, Ellis, Alicia M, George, Dylan B, Le Menach, Arnaud, Pulliam, Juliet RC, Bisanzio, Donal, Buckee, Caroline, Chiyaka, Christinah, Cummings, Derek AT, Garcia, Andres J, Gatton, Michelle L, Gething, Peter W, Hartley, David M, Johnston, Geoffrey, Klein, Eili Y, Michael, Edwin, Lindsay, Steven W, Lloyd, Alun L, Pigott, David M, Reisen, William K, Ruktanonchai, Nick, Singh, Brajendra K, Tatem, Andrew J, Kitron, Uriel, Hay, Simon I, Scott, Thomas W, and Smith, David L

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Vector-Borne Diseases, Infectious Diseases, Infection, Good Health and Well Being, Animals, Communicable Diseases, Culicidae, Geography, Host-Pathogen Interactions, Insect Vectors, Models, Biological, infectious disease dynamics, vector-borne disease, epidemiology, dengue, West Nile, filariasis, General Science & Technology
Abstract

Mathematical models of mosquito-borne pathogen transmission originated in the early twentieth century to provide insights into how to most effectively combat malaria. The foundations of the Ross-Macdonald theory were established by 1970. Since then, there has been a growing interest in reducing the public health burden of mosquito-borne pathogens and an expanding use of models to guide their control. To assess how theory has changed to confront evolving public health challenges, we compiled a bibliography of 325 publications from 1970 through 2010 that included at least one mathematical model of mosquito-borne pathogen transmission and then used a 79-part questionnaire to classify each of 388 associated models according to its biological assumptions. As a composite measure to interpret the multidimensional results of our survey, we assigned a numerical value to each model that measured its similarity to 15 core assumptions of the Ross-Macdonald model. Although the analysis illustrated a growing acknowledgement of geographical, ecological and epidemiological complexities in modelling transmission, most models during the past 40 years closely resemble the Ross-Macdonald model. Modern theory would benefit from an expansion around the concepts of heterogeneous mosquito biting, poorly mixed mosquito-host encounters, spatial heterogeneity and temporal variation in the transmission process.

Published
2013

44. From a general anti-cancer treatment to antioxidant or deer osteoporosis: the consequences of antler as the fastest-growing tissue.

Author

Landete-Castillejos, Tomás, Rossetti, Alessandra, Garcia, Andres J., de Cabo, Carlos, Festuccia, Claudio, Luna, Salvador, and Chonco, Louis

Abstract

Deer antlers are unique because they are cast and regenerate each year. They are the fastest-growing structure, reaching an astonishing growth rate of up to 2.75 cm/day in length and more than 20 cm2/day of skin. Surprisingly, no study so far has assessed the metabolic rate of the antler. High metabolic rate needs highly efficient (or large) mitochondria, and it involves a high creation or reactive oxygen species (ROS), origin of oxidative stress. The speed of creation of ROS and the oxidative stress are inversely related to ageing and many diseases such as cancer or age-related diseases. However, antler must have the most efficient anti-oxidant system, as it rarely shows any departure from a perfect growth. This paper examines recent studies showing surprising applications in medicine of growing-antler extracts, or the information regarding its physiology. A recent study (Wang et al. (2019) , Science 364, eaav6335) has shown that antlers have evolved a speed of growth faster than cancer, based on high expression of proto-oncogenes. As a result, deer has evolved tumour-suppression genes to control the high risk of developing cancer. This may explain why several studies have found in vitro and in vivo anti-cancer effects of deer velvet-antler extract in human tumours, such as cell cultures and animal models of cancers such as brain cancer (glioblastoma), prostate cancer, and others. We will also discuss findings in the study of the cyclic osteoporosis of the deer, with unexpected similarities in their proteomics and gene expression with that of the human pathological osteoporosis. Last, we will examine potential applications based on having the highest metabolic rate. If the future studies establish the antler as the tissue having the fastest metabolism and the best antioxidant system, this may have implications for understanding how to fight oxidative stress, which, in turn, will have direct implications for aging and age-related diseases (and others, from cancer to osteoporosis and Alzheimer's for example). It may also show that velvet-antler extract is a general anti-cancer compound, and this may show the path to find an anti-cancer medicine that has no secondary toxic effects in healthy cells. Antler is the only mammal structure regenerating each year, and it is the fastest-growing tissue (much faster-growing than cancer). For this reason, several interesting medical applications are reviewed in this paper, such as anti-cancer activity of growing-antler extract. Studying growing antler may help develop powerful and general anti-cancer treatments without secondary effects, and the high metabolic rate and antioxidant system of the antler may also have other potential medical applications, such as delaying aging- or fight-associated diseases. [ABSTRACT FROM AUTHOR]

Published
2023
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