4,316 results on '"García-García P"'
Search Results
2. $\mathtt{emuflow}$: Normalising Flows for Joint Cosmological Analysis
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Mootoovaloo, Arrykrishna, García-García, Carlos, Alonso, David, and Ruiz-Zapatero, Jaime
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Astrophysics - Cosmology and Nongalactic Astrophysics ,Computer Science - Machine Learning - Abstract
Given the growth in the variety and precision of astronomical datasets of interest for cosmology, the best cosmological constraints are invariably obtained by combining data from different experiments. At the likelihood level, one complication in doing so is the need to marginalise over large-dimensional parameter models describing the data of each experiment. These include both the relatively small number of cosmological parameters of interest and a large number of "nuisance" parameters. Sampling over the joint parameter space for multiple experiments can thus become a very computationally expensive operation. This can be significantly simplified if one could sample directly from the marginal cosmological posterior distribution of preceding experiments, depending only on the common set of cosmological parameters. In this paper, we show that this can be achieved by emulating marginal posterior distributions via normalising flows. The resulting trained normalising flow models can be used to efficiently combine cosmological constraints from independent datasets without increasing the dimensionality of the parameter space under study. We show that the method is able to accurately describe the posterior distribution of real cosmological datasets, as well as the joint distribution of different datasets, even when significant tension exists between experiments. The resulting joint constraints can be obtained in a fraction of the time it would take to combine the same datasets at the level of their likelihoods. We construct normalising flow models for a set of public cosmological datasets of general interests and make them available, together with the software used to train them, and to exploit them in cosmological parameter inference., Comment: 13 pages, 5 figures
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- 2024
3. Scant evidence for thawing quintessence
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Wolf, William J., García-García, Carlos, Bartlett, Deaglan J., and Ferreira, Pedro G.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,General Relativity and Quantum Cosmology ,High Energy Physics - Phenomenology ,High Energy Physics - Theory - Abstract
New constraints on the expansion rate of the Universe seem to favor evolving dark energy in the form of thawing quintessence models, i.e., models for which a canonical, minimally coupled scalar field has, at late times, begun to evolve away from potential energy domination. We scrutinize the evidence for thawing quintessence by exploring what it predicts for the equation of state. We show that, in terms of the usual Chevalier-Polarski-Linder parameters, ($w_0$, $w_a$), thawing quintessence is, in fact, only marginally consistent with a compilation of the current data. Despite this, we embrace the possibility that thawing quintessence is dark energy and find constraints on the microphysics of this scenario. We do so in terms of the effective mass $m^2$ and energy scale $V_0$ of the scalar field potential. We are particularly careful to enforce un-informative, flat priors on these parameters so as to minimize their effect on the final posteriors. While the current data favors a large and negative value of $m^2$, when we compare these models to the standard $\Lambda$CDM model we find that there is scant evidence for thawing quintessence., Comment: Accepted and forthcoming in PRD. Minor changes to discussions. 18 pages, 14 figures
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- 2024
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4. Learning Confidence Bounds for Classification with Imbalanced Data
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Clifford, Matt, Erskine, Jonathan, Hepburn, Alexander, Santos-Rodríguez, Raúl, and Garcia-Garcia, Dario
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Computer Science - Machine Learning - Abstract
Class imbalance poses a significant challenge in classification tasks, where traditional approaches often lead to biased models and unreliable predictions. Undersampling and oversampling techniques have been commonly employed to address this issue, yet they suffer from inherent limitations stemming from their simplistic approach such as loss of information and additional biases respectively. In this paper, we propose a novel framework that leverages learning theory and concentration inequalities to overcome the shortcomings of traditional solutions. We focus on understanding the uncertainty in a class-dependent manner, as captured by confidence bounds that we directly embed into the learning process. By incorporating class-dependent estimates, our method can effectively adapt to the varying degrees of imbalance across different classes, resulting in more robust and reliable classification outcomes. We empirically show how our framework provides a promising direction for handling imbalanced data in classification tasks, offering practitioners a valuable tool for building more accurate and trustworthy models., Comment: Accepted at ECAI 2024 main track
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- 2024
5. Assessment of Gradient-Based Samplers in Standard Cosmological Likelihoods
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Mootoovaloo, Arrykrishna, Ruiz-Zapatero, Jaime, García-García, Carlos, and Alonso, David
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We assess the usefulness of gradient-based samplers, such as the No-U-Turn Sampler (NUTS), by comparison with traditional Metropolis-Hastings algorithms, in tomographic $3 \times 2$ point analyses. Specifically, we use the DES Year 1 data and a simulated future LSST-like survey as representative examples of these studies, containing a significant number of nuisance parameters (20 and 32, respectively) that affect the performance of rejection-based samplers. To do so, we implement a differentiable forward model using JAX-COSMO (Campagne et al. 2023), and we use it to derive parameter constraints from both datasets using the NUTS algorithm as implemented in {\S}4, and the Metropolis-Hastings algorithm as implemented in Cobaya (Lewis 2013). When quantified in terms of the number of effective number of samples taken per likelihood evaluation, we find a relative efficiency gain of $\mathcal{O}(10)$ in favour of NUTS. However, this efficiency is reduced to a factor $\sim 2$ when quantified in terms of computational time, since we find the cost of the gradient computation (needed by NUTS) relative to the likelihood to be $\sim 4.5$ times larger for both experiments. We validate these results making use of analytical multi-variate distributions (a multivariate Gaussian and a Rosenbrock distribution) with increasing dimensionality. Based on these results, we conclude that gradient-based samplers such as NUTS can be leveraged to sample high dimensional parameter spaces in Cosmology, although the efficiency improvement is relatively mild for moderate $(\mathcal{O}(50))$ dimension numbers, typical of tomographic large-scale structure analyses., Comment: 14 pages and 9 figures
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- 2024
6. Increase in Self-Efficacy in Prospective Teachers through Theory-Based Lesson Study
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Elena M. Lendínez Muñoz, Francisco J. García García, Ana M. Lerma Fernández, and Ana M. Abril Gallego
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This paper explores the education of prospective teachers with regard to the Theory of Didactical Situations when they engage in lesson study. We particularly focus on studying how a lesson study process oriented towards the Theory of Didactical Situations contributes to increasing prospective teachers' self-efficacy to plan and teach lessons based on such theory, reducing the gap between theory and practice. Prior to the study, we will discuss how the theoretical postulates assumed in lesson study affect crucial aspects of the process. The study is implemented with 47 prospective early childhood education teachers. We also consider another group of 47 prospective teachers that were engaged in practicum at the time the lesson study process took place. Using a quasi-experimental methodology based on a questionnaire developed ad hoc that captures the particularities of the didactic paradigm assumed, the results of our study show that both lesson study and practicum lead to a statistically significant increase in future teachers' self-efficacy to plan and teach lessons in line with the paradigm assumed. However, size effect measures show that the increase observed in the lesson study group is significantly higher, which supports the benefits of lesson study in initial teacher education. We discuss what the features of lesson study are that could be related to this increase. Finally, we sketch new lines of research connected with the benefits of lesson study versus other teacher education experiences like practicum, as well as with links between self-efficacy and knowledge growth in lesson study.
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- 2024
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7. Geodetic Research on Deception Island and its Environment (South Shetland Islands, Bransfield Sea and Antarctic Peninsula) During Spanish Antarctic Campaigns (1987-2007)
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Berrocoso, M., Fernández-Ros, A., Ramírez, M. E., Salamanca, J. M., Torrecillas, C., Pérez-Peña, A., Páez, R., García-García, A., Jiménez-Teja, Y., García-García, F., Soto, R., Gárate, J., Martín-Davila, J., Sánchez-Alzola, A., de Gil, A., Fernández-Prada, J. A., and Jigena, B.
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Physics - Geophysics - Abstract
Since 1987, Spain has been continuously developing several scientific projects, mainly based on Earth Sciences, in Geodesy, Geochemistry, Geology or Volcanology. The need of a geodetic reference frame when doing hydrographic and topographic mapping meant the organization of the earlier campaigns with the main goals of updating the existing cartography and of making new maps of the area. During this period of time, new techniques arose in Space Geodesy improving the classical methodology and making possible its applications to other different fields such as tectonic or volcanism. Spanish Antarctic Geodetic activities from the 1987/1988 to 2006/2007 campaigns are described as well as a geodetic and a levelling network are presented. The first network, RGAE, was designed and established to define a reference frame in the region formed by the South Shetlands Islands, the Bransfield Sea and the Antarctic Peninsula whereas the second one, REGID, was planned to control the volcanic activity in Deception Island. Finally, the horizontal and vertical deformation models are described too, as well as the strategy which has been followed when computing an experimental geoid.
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- 2024
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8. IReNe: Instant Recoloring of Neural Radiance Fields
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Mazzucchelli, Alessio, Garcia-Garcia, Adrian, Garces, Elena, Rivas-Manzaneque, Fernando, Moreno-Noguer, Francesc, and Penate-Sanchez, Adrian
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Advances in NERFs have allowed for 3D scene reconstructions and novel view synthesis. Yet, efficiently editing these representations while retaining photorealism is an emerging challenge. Recent methods face three primary limitations: they're slow for interactive use, lack precision at object boundaries, and struggle to ensure multi-view consistency. We introduce IReNe to address these limitations, enabling swift, near real-time color editing in NeRF. Leveraging a pre-trained NeRF model and a single training image with user-applied color edits, IReNe swiftly adjusts network parameters in seconds. This adjustment allows the model to generate new scene views, accurately representing the color changes from the training image while also controlling object boundaries and view-specific effects. Object boundary control is achieved by integrating a trainable segmentation module into the model. The process gains efficiency by retraining only the weights of the last network layer. We observed that neurons in this layer can be classified into those responsible for view-dependent appearance and those contributing to diffuse appearance. We introduce an automated classification approach to identify these neuron types and exclusively fine-tune the weights of the diffuse neurons. This further accelerates training and ensures consistent color edits across different views. A thorough validation on a new dataset, with edited object colors, shows significant quantitative and qualitative advancements over competitors, accelerating speeds by 5x to 500x.
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- 2024
9. Emergence of spatial patterns and synchronization in superconducting time crystals
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Fan, Bo, Cai, Zi, and García-García, Antonio M.
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Condensed Matter - Superconductivity ,Condensed Matter - Disordered Systems and Neural Networks ,Condensed Matter - Strongly Correlated Electrons ,Quantum Physics - Abstract
We identify a time crystal phase characterized by a frequency half of the driving frequency in disordered superconductors by employing the time dependent Bogoliubov-de Gennes formalism at zero temperature with a periodically driven coupling constant. After a period of exponential increase of spatial inhomogeneities and exponential suppression of the order parameter amplitude, the time crystal develops islands of different sizes. Each of these islands is a time crystal with the same frequency albeit with a phase shift $\pi$ with respect to the homogeneous time crystal. After its emergence, the island gradually becomes smaller, though the phase shift persists, until it is abruptly synchronized at a time that it depends on its initial size. We find a critical disorder strength, still deep in the metallic phase, at which the time crystal phase terminates. For even stronger disorder, the order parameter oscillates with the driving frequency in regions where localization effects are not important., Comment: 30 pages, 23 figures
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- 2024
10. On ideals of affine semigroups and affine semigroups with maximal embedding dimension
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García-García, J. I., Tapia-Ramos, R., and Vigneron-Tenorio, A.
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Mathematics - Commutative Algebra ,20M14, 20M12 - Abstract
Let $S\subseteq \mathbb N^p$ be a semigroup, any $P\subseteq S$ is an ideal of $S$ if $P+S\subseteq P$, and an $I(S)$-semigroup is the affine semigroup $P\cup \{0\}$, with $P$ an ideal of $S$. We characterise the $I(S)$-semigroups and the ones that also are $\mathcal C$-semigroups. Moreover, some algorithms are provided to compute all the $I(S)$-semigroups satisfying some properties. From a family of ideals of $S$, we introduce the affine semigroups with maximal embedding dimension, characterising them and describing some families.
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- 2024
11. A semi-analytical model for the propagation of a structured jet in a magnetized medium
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Garcia-Garcia, Leonardo, Lopez-Camara, Diego, and Lazzati, Davide
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The merger of two magnetized compact objects, such as neutron stars, forms a compact object which may launch a relativistic and collimated jet. Numerical simulations of the process show that a dense and highly magnetized medium surrounds the system. This study presents a semi-analytical model that models the effects that a static magnetized medium with a tangled field produces in relativistic, collimated, and non-magnetized jets. The model is a first approximation that addresses the magnetic field present in the medium and is based on pressure equilibrium principles between the jet, cocoon, and external medium. A fraction of the ambient medium field is allowed to be entrained in the cocoon. We find that the jet and cocoon properties may be affected by high magnetic fields ($\gtrsim 10^{15}$~G) and mixing. The evolution of the system may vary up to $\sim10\%$ (compared to the non-magnetized case). Low-mixing may produce a slower-broader jet with a broader and more energetic cocoon would be produced. On the other hand, high-mixing could produce a faster-narrower jet with a narrow and less-energetic cocoon. Two-dimensional hydrodynamical simulations are used to validate the model and to constrain the mixing parameter. Although the magnetic field and mixing have a limited effect, our semi-analytic model captures the general trend consistent with numerical results. For high magnetization, the results were found to be more consistent with the low mixing case in our semi-analytic model., Comment: 10 pages, 6 figures, 1 table, submitted to MNRAS
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- 2024
12. Cosmic shear with small scales: DES-Y3, KiDS-1000 and HSC-DR1
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García-García, Carlos, Zennaro, Matteo, Aricò, Giovanni, Alonso, David, and Angulo, Raul E.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present a cosmological analysis of the combination of the DES-Y3, KiDS-1000 and HSC-DR1 weak lensing samples under a joint harmonic-space pipeline making use of angular scales down to $\ell_{\rm max}=4500$, corresponding to significantly smaller scales ($\delta\theta\sim2.4'$) than those commonly used in cosmological weak lensing studies. We are able to do so by accurately modelling non-linearities and the impact of baryonic effects using Baccoemu. We find $S_8\equiv\sigma_8\sqrt{\Omega_{\rm m}/0.3}=0.795^{+0.015}_{-0.017}$, in relatively good agreement with CMB constraints from Planck (less than $\sim1.8\sigma$ tension), although we obtain a low value of $\Omega_{\rm m}=0.212^{+0.017}_{-0.032}$, in tension with Planck at the $\sim3\sigma$ level. We show that this can be recast as an $H_0$ tension if one parametrises the amplitude of fluctuations and matter abundance in terms of variables without hidden dependence on $H_0$. Furthermore, we find that this tension reduces significantly after including a prior on the distance-redshift relationship from BAO data, without worsening the fit. In terms of baryonic effects, we show that failing to model and marginalise over them on scales $\ell\lesssim2000$ does not significantly affect the posterior constraints for DES-Y3 and KiDS-1000, but has a mild effect on deeper samples, such as HSC-DR1. This is in agreement with our ability to only mildly constrain the parameters of the Baryon Correction Model with these data, Comment: v1: 57 pages, 24 figures, comments welcome. v2: accepted version in JCAP
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- 2024
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13. The Lyapunov exponent as a signature of dissipative many-body quantum chaos
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García-García, Antonio M., Verbaarschot, Jacobus J. M., and Zheng, Jie-ping
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High Energy Physics - Theory ,Condensed Matter - Strongly Correlated Electrons ,Quantum Physics - Abstract
A distinct feature of Hermitian quantum chaotic dynamics is the exponential increase of certain out-of-time-order-correlation (OTOC) functions around the Ehrenfest time with a rate given by a Lyapunov exponent. Physically, the OTOCs describe the growth of quantum uncertainty that crucially depends on the nature of the quantum motion. Here, we employ the OTOC in order to provide a precise definition of dissipative quantum chaos. For this purpose, we compute analytically the Lyapunov exponent for the vectorized formulation of the large $q$-limit of a $q$-body Sachdev-Ye-Kitaev model coupled to a Markovian bath. These analytic results are confirmed by an explicit numerical calculation of the Lyapunov exponent for several values of $q \geq 4$ based on the solutions of the Schwinger-Dyson and Bethe-Salpeter equations. We show that the Lyapunov exponent decreases monotonically as the coupling to the bath increases and eventually becomes negative at a critical value of the coupling signaling a transition to a dynamics which is no longer quantum chaotic. Therefore, a positive Lyapunov exponent is a defining feature of dissipative many-body quantum chaos. The observation of the breaking of the exponential growth for sufficiently strong coupling suggests that dissipative quantum chaos may require in certain cases a sufficiently weak coupling to the environment., Comment: 32 pages, 4 figures, we have added references and made minor corrections
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- 2024
14. Modelling Global Fossil CO2 Emissions with a Lognormal Distribution: A Climate Policy Tool
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Prieto, Faustino, García-García, Catalina B., and Gómez, Román Salmerón
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Economics - General Economics - Abstract
Carbon dioxide (CO2) emissions have emerged as a critical issue with profound impacts on the environment, human health, and the global economy. The steady increase in atmospheric CO2 levels, largely due to human activities such as burning fossil fuels and deforestation, has become a major contributor to climate change and its associated catastrophic effects. To tackle this pressing challenge, a coordinated global effort is needed, which necessitates a deep understanding of emissions patterns and trends. In this paper, we explore the use of statistical modelling, specifically the lognormal distribution, as a framework for comprehending and predicting CO2 emissions. We build on prior research that suggests a complex distribution of emissions and seek to test the hypothesis that a simpler distribution can still offer meaningful insights for policy-makers. We utilize data from three comprehensive databases and analyse six candidate distributions (exponential, Fisk, gamma, lognormal, Lomax, Weibull) to identify a suitable model for global fossil CO2 emissions. Our findings highlight the adequacy of the lognormal distribution in characterizing emissions across all countries and years studied. Furthermore, to provide additional support for this distribution, we provide statistical evidence supporting the applicability of Gibrat's law to those CO2 emissions. Finally, we employ the lognormal model to predict emission parameters for the coming years and propose two policies for reducing total fossil CO2 emissions. Our research aims to provide policy-makers with accurate and detailed information to support effective climate change mitigation strategies., Comment: 28 pages, 6 figures
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- 2024
15. Comparative analysis of the efficacy and complications of mid-urethral slings when inserted either in isolation or in conjunction with pelvic organ prolapse surgery
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Pérez, Esther Ruiz, De Miguel Manso, Sonia, García García, Elena, Tejedor, Julio Alberto Gobernado, Díaz-Heredero, Álvaro Sanz, Del Nogal, Lidia Casamayor, Martínez, Sandra Canales, and Pascual, Jimena Bayón
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- 2024
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16. SEOM-GEICO Clinical Guidelines on cervical cancer (2023)
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Manso, Luis, Ramchandani-Vaswani, Avinash, Romero, Ignacio, Sánchez-Lorenzo, Luisa, Bermejo-Pérez, María José, Estévez-García, Purificación, Fariña-Madrid, Lorena, García García, Yolanda, Gil-Martin, Marta, and Quindós, María
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- 2024
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17. Changes in Noradrenergic Synthesis and Dopamine Beta-Hydroxylase Activity in Response to Oxidative Stress after Iron-induced Brain Injury
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Verduzco-Mendoza, Antonio, Mota-Rojas, Daniel, Olmos-Hernández, Adriana, Avila-Luna, Alberto, García-García, Karla, Gálvez-Rosas, Arturo, Hidalgo-Bravo, Alberto, Ríos, Camilo, Parra-Cid, Carmen, Montes, Sergio, García-López, Julieta, Ramos-Languren, Laura E., Pérez-Severiano, Francisca, González-Piña, Rigoberto, and Bueno-Nava, Antonio
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- 2024
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18. Effect of Amendments on the Adsorption and Mineralization of Atrazine in an Agricultural Soil
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García-Sánchez, J. J., Solache-Ríos, M., Sánchez-Orozco, R., Soriano-Vargas, O., Díaz-Nava, M. C., and García-García, J. J.
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- 2024
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19. Profile of plasma microRNAs as a potential biomarker of Wilson’s disease
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Sánchez-Monteagudo, Ana, Ripollés, Edna, Murillo, Oihana, Domènech, Sofia, Álvarez-Sauco, María, Girona, Eva, Sastre-Bataller, Isabel, Bono, Ariadna, García-Villarreal, Luis, Tugores, Antonio, García-García, Francisco, González-Aseguinolaza, Gloria, Berenguer, Marina, and Espinós, Carmen
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- 2024
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20. Magnetic and pH-responsive magnetite/chitosan (core/shell) nanoparticles for dual-targeted methotrexate delivery in cancer therapy
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Medina-Moreno, Ana, El-Hammadi, Mazen M., Martínez-Soler, Gema I., Ramos, Javier G., García-García, Gracia, and Arias, José L.
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- 2024
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21. Effects of Strength Exercise on Pain Management and Quality of Life in Subjects with Systemic Peripheral Neuropathies: a Systematic Review and Meta-Analysis
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Maldonado-Cobalea, Ignacio, López-González, Luis, Cervera-Cano, María, Díaz-Román, Amparo, Lázaro-Navas, Irene, Valcárcel-Linares, David, and García-García, Unai
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- 2024
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22. On the quotient of affine semigroups by a positive integer
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García-García, J. I., Tapia-Ramos, R., and Vigneron-Tenorio, A.
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Mathematics - Commutative Algebra ,Mathematics - Number Theory - Abstract
This work delves into the {\it quotient of an affine semigroup by a positive integer}, exploring its intricate properties and broader implications. We unveil an {\it associated tree} that serves as a valuable tool for further analysis. Moreover, we successfully generalize several key irreducibility results, extending their applicability to the more general class of $\mathcal C$-semigroup quotients. To shed light on these concepts, we introduce the novel notion of an {\it arithmetic variety of affine semigroups}, accompanied by illuminating examples that showcase its power.
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- 2024
23. LFOC: A Lightweight Fairness-Oriented Cache Clustering Policy for Commodity Multicores
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García-García, Adrián, Sáez, Juan Carlos, Castro, Fernando, and Prieto-Matías, Manuel
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Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Hardware Architecture - Abstract
Multicore processors constitute the main architecture choice for modern computing systems in different market segments. Despite their benefits, the contention that naturally appears when multiple applications compete for the use of shared resources among cores, such as the last-level cache (LLC), may lead to substantial performance degradation. This may have a negative impact on key system aspects such as throughput and fairness. Assigning the various applications in the workload to separate LLC partitions with possibly different sizes, has been proven effective to mitigate shared-resource contention effects. In this article we propose LFOC, a clustering-based cache partitioning scheme that strives to deliver fairness while providing acceptable system throughput. LFOC leverages the Intel Cache Allocation Technology (CAT), which enables the system software to divide the LLC into different partitions. To accomplish its goals, LFOC tries to mimic the behavior of the optimal cache-clustering solution, which we could approximate by means of a simulator in different scenarios. To this end, LFOC effectively identifies streaming aggressor programs and cache sensitive applications, which are then assigned to separate cache partitions. We implemented LFOC in the Linux kernel and evaluated it on a real system featuring an Intel Skylake processor, where we compare its effectiveness to that of two state-of-the-art policies that optimize fairness and throughput, respectively. Our experimental analysis reveals that LFOC is able to bring a higher reduction in unfairness by leveraging a lightweight algorithm suitable for adoption in a real OS.
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- 2024
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24. Growth history and quasar bias evolution at z < 3 from Quaia
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Piccirilli, G., Fabbian, G., Alonso, D., Storey-Fisher, K., Carron, J., Lewis, A., and García-García, C.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We make use of the Gaia-Unwise quasar catalogue, Quaia, to constrain the growth history out to high redshifts from the clustering of quasars and their cross-correlation with maps of the Cosmic Microwave Background (CMB) lensing convergence. Considering three tomographic bins, centered at redshifts $\bar{z}_i = [0.69, 1.59, 2.72]$, we reconstruct the evolution of the amplitude of matter fluctuations $\sigma_8(z)$ over the last $\sim12$ billion years of cosmic history. In particular, we make one of the highest-redshift measurements of $\sigma_8$ ($\sigma_8(z=2.72)=0.22\pm 0.06$), finding it to be in good agreement (at the $\sim1\sigma$ level) with the value predicted by $\Lambda$CDM using CMB data from Planck. We also used the data to study the evolution of the linear quasar bias for this sample, finding values similar to those of other quasar samples, although with a less steep evolution at high redshifts. Finally, we study the potential impact of foreground contamination in the CMB lensing maps and, although we find evidence of contamination in cross-correlations at $z\sim1.7$ we are not able to clearly pinpoint its origin as being Galactic or extragalactic. Nevertheless, we determine that the impact of this contamination on our results is negligible., Comment: 28 pages, 11 figures
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- 2024
25. Quenched dynamics and pattern formation in clean and disordered Bogoliubov-de Gennes superconductors
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Fan, Bo and García-García, Antonio M.
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Condensed Matter - Superconductivity ,Condensed Matter - Disordered Systems and Neural Networks - Abstract
We study the quench dynamics of a two dimensional superconductor in a lattice of size up to $200\times 200$ employing the self-consistent time dependent Bogoliubov-de Gennes (BdG) formalism. In the clean limit, the dynamics of the order parameter for short times, characterized by a fast exponential growth and an oscillatory pattern, agrees with the Bardeen-Cooper-Schrieffer (BCS) prediction. However, unlike BCS, we observe for longer times an universal exponential decay of these time oscillations that we show explicitly to be induced by the full emergence of spatial inhomogeneities of the order parameter, even in the clean limit, characterized by the exponential growth of its variance. The addition of a weak disorder does not alter these results qualitatively. In this region, the spatial inhomogeneities rapidly develops into an intricate spatial structure consisting of ordered fragmented stripes in perpendicular directions where the order parameter is heavily suppressed especially in the central region. As the disorder strength increases, the fragmented stripes gradually turn into a square lattice of approximately circular spatial regions where the condensate is heavily suppressed. A further increase of disorder leads to the deformation and ultimate destruction of this lattice. We explore suitable settings for the experimental confirmation of these findings., Comment: 27 pages and 16 figures. References added
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- 2023
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26. Mexican Clinical Practice Guidelines for Adult Overweight and Obesity Management
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Chávez-Manzanera, Emma A., Vera-Zertuche, Juan M., Kaufer-Horwitz, Martha, Vázquez-Velázquez, Verónica, Flores-Lázaro, José R., Mireles-Zavala, Leonor, Calzada-León, Raúl, Garnica-Cuellar, Juan C., Sánchez-Muñoz, Verónica, Ramírez-Butanda, Eduardo, Hernández-González, Ricardo, Vargas-Martínez, María A., Laviada-Molina, Hugo, Violante-Ortíz, Rafael, Esquivias-Zavala, Héctor, García-García, Eduardo, Lavalle-González, Fernando J., Mancillas-Adame, Leonardo, López-Alvarenga, Juan C., Pérez-Hernández, Juan F., Soto-Fuentes, Erika V., Soriano-Cortés, Reina R., Goicoechea-Turcott, Eduardo W., Magallanes-Díaz, Gerardo, Herrera-Hernández, Miguel F., Barquera-Cervera, Simón, Vargas-Contreras, Edith, Díaz-Wionczek, Cybele B., Salmon, Morgan, Jesús, Dinorah Ramírez-De, Villaseñor-Díaz, Juan P., Peña, Javiera, Ramos-Rojas, José, Ávila-Oliver, Camila, Rada, Gabriel, Hussey, Brad, and Salas, Ximena Ramos
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- 2024
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27. Carotid-femoral pulse wave velocity score, an estimator of cognitive performance in the elderly: results from the Toledo Study for Healthy Aging
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Bareiro, Fabio A. Quiñónez, Carnicero, José A., Acha, Ana Alfaro, Artalejo, Cristina Rosado, Jimenez, María C. Grau, Mañas, Leocadio Rodriguez, and García García, Francisco J.
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- 2024
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28. Plasma Levels of Neuron/Glia-Derived Apoptotic Bodies, an In Vivo Biomarker of Apoptosis, Predicts Infarct Growth and Functional Outcome in Patients with Ischemic Stroke
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Díaz-Maroto, Inmaculada, Castro-Robles, Beatriz, Villar, Miguel, García-García, Jorge, Ayo-Martín, Óscar, Serrano-Heras, Gemma, and Segura, Tomás
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- 2024
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29. On the analytical solution of transient friction in channel flows
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García-García, F. J. and Fariñas-Alvariño, P.
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- 2024
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30. The best linear unbiased prediction (BLUP) method as a tool to estimate the lifetime risk of pancreatic ductal adenocarcinoma in high-risk individuals with no known pathogenic germline variants
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Cristina-Marianini-Rios, Sanchez, María E. Castillo, de Paredes, Ana García García, Rodríguez, Mercedes, Barreto, Emma, López, Jorge Villalón, Fuentes, Raquel, Beltrán, María Muñoz, Sanjuanbenito, Alfonso, Lobo, Eduardo, Caminoa, Alejandra, Ruz-Caracuel, Ignacio, Durán, Sergio López, Olcina, José Ramón Foruny, Blázquez, Javier, Sequeros, Enrique Vázquez, Carrato, Alfredo, Ávila, Jose Carlos Martínez, and Earl, Julie
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- 2024
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31. The Spanish Familial Pancreatic Cancer Registry (PANGENFAM): a decade follow-up of individuals at high-risk for pancreatic cancer
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Earl, Julie, Fuentes, Raquel, Sanchez, María E. Castillo, de Paredes, Ana García García, Muñoz, María, Sanjuanbenito, Alfonso, Lobo, Eduardo, Caminoa, Alejandra, Rodríguez, Mercedes, Barreto, Emma, López, Jorge Villalón, Ruz-Caracuel, Ignacio, Durán, Sergio López, Olcina, José Ramón Foruny, Sánchez, Bárbara Luna, Páez, Sonia Camaño, Torres, Ana, Blázquez, Javier, Sequeros, Enrique Vázquez, and Carrato, Alfredo
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- 2024
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32. Tisochrysis lutea as a source of omega-3 polar lipids and fucoxanthin: extraction and characterization using green solvents and advanced techniques
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García-García, Paz, Ospina, Mónica, and Señoráns, Francisco J.
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- 2024
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33. Increase in self-efficacy in prospective teachers through theory-based lesson study
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Lendínez Muñoz, Elena M., García García, Francisco J., Lerma Fernández, Ana M., and Abril Gallego, Ana M.
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- 2024
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34. On some properties of Cronbach’s α coefficient for interval-valued data in questionnaires
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García-García, José, Gil, María Ángeles, and Lubiano, María Asunción
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- 2024
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35. On the Selection of Catalysts’ Support with High Oxygen Delivery Capacity for DRM Application: Interest of Praseodymium as Dopant of Ceria
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Herráez-Santos, L., Goma-Jiménez, D., Yeste-Sigüenza, M. P., Cauqui-López, M. A., and García-García, A.
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- 2024
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36. Conventional and microfluidic methods: Design and optimization of lipid-polymeric hybrid nanoparticles for gene therapy
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González-García, Daniel, Tapia, Olga, Évora, Carmen, García-García, Patricia, and Delgado, Araceli
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- 2024
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37. Toward a classification of PT-symmetric quantum systems: From dissipative dynamics to topology and wormholes
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García-García, Antonio M., Sá, Lucas, Verbaarschot, Jacobus J. M., and Yin, Can
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Quantum Physics ,Condensed Matter - Statistical Mechanics ,Condensed Matter - Strongly Correlated Electrons ,High Energy Physics - Theory - Abstract
Studies of many-body non-Hermitian parity-time (PT)-symmetric quantum systems are attracting a lot of interest due to their relevance in research areas ranging from quantum optics and continuously monitored dynamics to Euclidean wormholes in quantum gravity and dissipative quantum chaos. While a symmetry classification of non-Hermitian systems leads to 38 universality classes, we show that, under certain conditions, PT-symmetric systems are grouped into 24 universality classes. We identify 14 of them in a coupled two-site Sachdev-Ye-Kitaev (SYK) model and confirm the classification by spectral analysis using exact diagonalization techniques. Intriguingly, in 4 of these 14 universality classes, AIII$_\nu$, BDI$^\dagger_\nu$, BDI$_{++\nu}$, and CI$_{--\nu}$, we identify a basis in which the SYK Hamiltonian has a block structure in which some blocks are rectangular, with $\nu \in \mathbb{N}$ the difference between the number of rows and columns. We show analytically that this feature leads to the existence of $\nu$ robust purely \emph{real} eigenvalues, whose level statistics follow the predictions of Hermitian random matrix theory for classes A, AI, BDI, and CI, respectively. We have recently found that this $\nu$ is a topological invariant, so these classes are topological. By contrast, nontopological real eigenvalues display a crossover between Hermitian and non-Hermitian level statistics. Similarly to the case of Lindbladian dynamics, the reduction of universality classes leads to unexpected results, such as the absence of Kramers degeneracy in a given sector of the theory. Another novel feature of the classification scheme is that different sectors of the PT-symmetric Hamiltonian may have different symmetries., Comment: 66 pages, 9 figures, 19 tables. v2: expanded Sec. IIC and minor corrections, as published
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- 2023
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38. Emergent Topology in Many-Body Dissipative Quantum Matter
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García-García, Antonio M., Sá, Lucas, Verbaarschot, Jacobus J. M., and Yin, Can
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Condensed Matter - Strongly Correlated Electrons ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Statistical Mechanics ,High Energy Physics - Theory ,Quantum Physics - Abstract
The identification, description, and classification of topological features is an engine of discovery and innovation in several fields of physics. This research encompasses a broad variety of systems, from the integer and fractional Chern insulators in condensed matter, to protected states in complex photonic lattices in optics, and the structure of the QCD vacuum. Here, we introduce another playground for topology: the dissipative dynamics of pseudo-Hermitian many-body quantum systems. For that purpose, we study two different systems, the dissipative Sachdev-Ye-Kitaev (SYK) model, and a quantum chaotic dephasing spin chain. For the two different many-body models, we find the same topological features for a wide range of parameters suggesting that they are universal. In the SYK model, we identify four universality classes, related to pseudo-Hermiticity, characterized by a rectangular block representation of the vectorized Liouvillian that is directly related to the existence of an anomalous trace of the unitary operator implementing fermionic exchange. As a consequence of this rectangularization, we identify a topological index $\nu$ that only depends on symmetry. Another distinct consequence of the rectangularization is the observation, for any coupling to the bath, of purely real topological modes in the Liouvillian. The level statistics of these real modes agree with that of the corresponding random matrix ensemble and therefore can be employed to characterize the four topological symmetry classes. In the limit of weak coupling to the bath, topological modes govern the approach to equilibrium, which may enable a direct path for experimental confirmation of topology in dissipative many-body quantum chaotic systems., Comment: 14 pages, 9 figures. v2: references added. v3: expanded discussion of universality, plus minor corrections
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- 2023
39. On $p$-Frobenius of affine semigroups
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Barroso, Evelia R. García, García-García, Juan Ignacio, Sánchez, Luis José Santana, and Vigneron-Tenorio, Alberto
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Mathematics - Commutative Algebra ,Mathematics - Number Theory - Abstract
The aim of this paper is to study the $p$-Frobenius vector of affine semigroups $S\subset \mathbb N^q$; that is, the maximum element, with respect to a graded monomial order, with at most $p$ factorizations in $S$. We produce several algorithms to compute these vectors. Finally, we study how the $p$-Frobenius vectors behave when considering gluings of $S$ with $\mathbb N^q$.
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- 2023
40. Sparsity independent Lyapunov exponent in the Sachdev-Ye-Kitaev model
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García-García, Antonio M., Liu, Chang, and Verbaarschot, Jacobus J. M.
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High Energy Physics - Theory ,Condensed Matter - Disordered Systems and Neural Networks ,Quantum Physics - Abstract
The saturation of a recently proposed universal bound on the Lyapunov exponent has been conjectured to signal the existence of a gravity dual. This saturation occurs in the low temperature limit of the dense Sachdev-Ye-Kitaev (SYK) model, $N$ Majorana fermions with $q$-body ($q>2$) infinite-range interactions. We calculate certain Out of Time Order Correlators (OTOC) for $N\le 64$ fermions for a highly sparse SYK model and find no significant dependence of the Lyapunov exponent on sparsity up to near the percolation limit where the Hamiltonian breaks up into blocks. This suggests that in the sparse case, the Lyapunov exponent also saturates the low-temperature bound. A key ingredient to reaching $N = 64$ is the development of a novel quantum spin model simulation library that implements highly-optimized matrix-free Krylov subspace methods on Graphical Processing Units (GPUs). This leads to a significantly lower simulation time as well as vastly reduced memory usage over previous approaches, while using modest computational resources. Strong sparsity-driven statistical fluctuations require both the use of a vastly larger number of disorder realizations with respect to the dense limit and a careful finite size scaling analysis. Our results potentially broadens the landscape of theories that may have a gravity analogue., Comment: 8 pages, 6 figures
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- 2023
41. LimberJack.jl: auto-differentiable methods for angular power spectra analyses
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Ruiz-Zapatero, J., Alonso, D., García-García, C., Nicola, A., Mootoovaloo, A., Sullivan, J. M., Bonici, M., and Ferreira, P. G.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We present LimberJack.jl, a fully auto-differentiable code for cosmological analyses of 2 point auto- and cross-correlation measurements from galaxy clustering, CMB lensing and weak lensing data written in Julia. Using Julia's auto-differentiation ecosystem, LimberJack.jl can obtain gradients for its outputs up to an order of magnitude faster than traditional finite difference methods. This makes LimberJack.jl greatly synergistic with gradient-based sampling methods, such as Hamiltonian Monte Carlo, capable of efficiently exploring parameter spaces with hundreds of dimensions. We first prove LimberJack.jl's reliability by reanalysing the DES Y1 3$\times$2-point data. We then showcase its capabilities by using a O(100) parameters Gaussian Process to reconstruct the cosmic growth from a combination of DES Y1 galaxy clustering and weak lensing data, eBOSS QSO's, CMB lensing and redshift-space distortions. Our Gaussian process reconstruction of the growth factor is statistically consistent with the $\Lambda$CDM Planck 2018 prediction at all redshifts. Moreover, we show that the addition of RSD data is extremely beneficial to this type of analysis, reducing the uncertainty in the reconstructed growth factor by $20\%$ on average across redshift. LimberJack.jl is a fully open-source project available on Julia's general repository of packages and GitHub., Comment: Accepted to OJA, corrected bug displaying wrong Fig. 9
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- 2023
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42. X-Ray-Cosmic-Shear Cross-Correlations: First Detection and Constraints on Baryonic Effects
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Ferreira, Tassia, Alonso, David, Garcia-Garcia, Carlos, and Chisari, Nora Elisa
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We report a first detection, at very high significance ($25\sigma$), of the cross-correlation between cosmic shear and the diffuse X-ray background, using data from the Dark Energy Survey and the ROSAT satellite. The X-ray cross-correlation signal is sensitive to the distribution of the surrounding gas in dark matter haloes. This allows us to use our measurements to place constraints on key physical parameters that determine the impact of baryonic effects in the matter power spectrum. In particular, we determine the mass of haloes in which feedback has expelled half of their gas content on average to be $\log_{10}(M_c/M_\odot)=13.643^{+0.081}_{-0.12}$, and the polytropic index of the gas to be $\Gamma = 1.231^{+0.015}_{-0.011}$. This represents a first step in the direct use of X-ray cross-correlations to obtain improved constraints on cosmology and the physics of the intergalactic gas., Comment: 6 pages, 3 figures, 1 table
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- 2023
43. Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial study protocol
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Lucía Guilabert, Karina Cárdenas-Jaén, Alicia Vaillo-Rocamora, Ana García García de Paredes, Ankit Chhoda, Sunil G. Sheth, Carlos López-Valero, Pedro Zapater, Eva M. Navarrete-Muñoz, Patrick Maisonneuve, Yasmin G. Hernández-Barco, Gabriele Capurso, James L. Buxbaum, Enrique de-Madaria, and for the ERICA consortium
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Acute pancreatitis ,Fluid resuscitation ,Lactated Ringer solution ,Normal saline ,Randomized controlled trial ,Medicine (General) ,R5-920 - Abstract
Abstract Background Some evidence suggests that fluid resuscitation with lactated Ringer’s solution (LR) may have an anti-inflammatory effect on acute pancreatitis (AP) when compared to normal saline (NS) and may be associated with a decrease in severity, but existing single-center randomized controlled trials showed conflicting results. The WATERLAND trial aims to investigate the efficacy and safety of fluid resuscitation using LR compared to NS in patients with AP. Methods The WATERLAND trial is an international multicenter, open-label, parallel-group, randomized, controlled, superiority trial. Patients will be randomly assigned in a 1:1 ratio to receive LR versus NS-based fluid resuscitation for at least 48 h. The primary outcome will be moderately severe or severe AP, according to the revision of the Atlanta classification. The secondary objectives of the WATERLAND trial are to determine the effect of LR versus NS fluid resuscitation on several efficacy and safety outcomes in patients with AP. A total sample of 720 patients, 360 in the LR group and 360 in the NS group, will achieve 90% power to detect a difference between the group proportions of 10%, assuming that the frequency of moderately severe or severe AP in the LR group will be 17%. A loss to follow-up of 10% of patients is expected, so the total sample size will be 396 patients in each treatment arm (792 patients overall). The test statistic used is the two-sided Z test with pooled variance set at a 0.05 significance level. Discussion The WATERLAND study aims to improve the early management of AP. Fluid resuscitation is an inexpensive treatment available in any hospital center worldwide. If a better evolution of pancreatitis is demonstrated in one of the treatment arms, it would have important repercussions in the management of this frequent disease. Trial registration ClinicalTrials.gov, NCT05781243. Registration date on January 4, 2023. EudraCT number 2023–000010-18, first posted March 23, 2023.
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- 2024
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44. The Impact of the Sociodemographic Profile on the Tourist Experience of the Fiesta de los Patios of Córdoba: An Analysis of Visitor Satisfaction
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Lucía Castaño-Prieto, Lucía García-García, Minerva Aguilar-Rivero, and José E. Ramos-Ruiz
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cultural tourism ,Fiesta de los Patios (Cordoba) ,Intangible Cultural Heritage ,satisfaction ,sociodemographic profile ,Archaeology ,CC1-960 - Abstract
The Festival of the Patios of Cordoba, declared an Intangible Cultural Heritage (ICH) by UNESCO in 2012, serves as an emblematic case of how this designation acts as a tourist brand, attracting a greater number of visitors and granting a competitive advantage to the city’s tourist market. This research is focused on analyzing the differences and similarities in the satisfaction, lived experience and behavioral intention of tourists according to their sociodemographic profile during the 2022 edition of the Patios Festival. The study’s main objective is to understand the sociodemographic profile of the tourist who visits this event and if there are features of this profile that influence the satisfaction and lived experience with the event. Using a quantitative methodological approach, field work was carried out during the Fiesta de los Patios of Cordoba (Spain) in its 2022 edition, which took place between 3 and 15 May 2022, obtaining 383 valid surveys. The results reveal differences in the perception and satisfaction of the experience depending on the sociodemographic profile of the visitors. These findings highlight the need to adapt the tourism offerings to improve the visitor experience and also contribute to the scarcity of studies on ICH to help tourism managers formulate strategies that maximize the cultural and economic benefits of these Word Heritage inscriptions.
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- 2024
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45. Deletion of exons 45 to 55 in the DMD gene: from the therapeutic perspective to the in vitro model
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Javier Poyatos-García, Patricia Soblechero-Martín, Alessandro Liquori, Andrea López-Martínez, Pilar Maestre, Elisa González-Romero, Rafael P. Vázquez-Manrique, Nuria Muelas, Gema García-García, Jessica Ohana, Virginia Arechavala-Gomeza, and Juan J. Vílchez
- Subjects
Duchenne muscular dystrophy ,Becker muscular dystrophy ,CRISPR-Cas9 ,Gene therapy ,Cell model ,Dystrophin ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Gene editing therapies in development for correcting out-of-frame DMD mutations in Duchenne muscular dystrophy aim to replicate benign spontaneous deletions. Deletion of 45–55 DMD exons (del45–55) was described in asymptomatic subjects, but recently serious skeletal and cardiac complications have been reported. Uncovering why a single mutation like del45–55 is able to induce diverse phenotypes and grades of severity may impact the strategies of emerging therapies. Cellular models are essential for this purpose, but their availability is compromised by scarce muscle biopsies. Methods We introduced, as a proof-of-concept, using CRISPR-Cas9 edition, a del45–55 mimicking the intronic breakpoints harboured by a subset of patients of this form of dystrophinopathy (designing specific gRNAs), into a Duchenne patient’s cell line. The edited cell line was characterized evaluating the dystrophin expression and the myogenic status. Results Dystrophin expression was restored, and the myogenic defects were ameliorated in the edited myoblasts harbouring a specific del45–55. Besides confirming the potential of CRISPR-Cas9 to create tailored mutations (despite the low cleavage efficiency of our gRNAs) as a useful approach to generate in vitro models, we also generated an immortalized myoblast line derived from a patient with a specific del45–55. Conclusions Overall, we provide helpful resources to deepen into unknown factors responsible for DMD-pathophysiology.
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- 2024
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46. The impact of linguistic immersion and economic, social and cultural status on academic performance
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Francisco López Rupérez, Álvaro Moraleda Ruano, and Isabel García García
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immersion programmes ,academic achievement ,educational equity ,educational policy ,educational assessment ,structural equation modelling ,Education (General) ,L7-991 - Abstract
The question of language in school has an educational dimension of considerable social interest in Spain since a strong process of immersion in regional languages might be affecting students’ performance depending on their linguistic and socio-cultural background. In this context, the paper’s aim is to analyse the relations between economic, social, and cultural status (ESCS); the percentage of students who speak a different language at school than at home (language) and school performance in PISA (performance); and in particular to measure the predictive power of the second variable with respect to the third, from a territorial perspective. A methodology was developed based on bivariate linear regression analysis and structural equation modelling, and was applied to data regarding these three variables from the PISA 2015 and PISA 2022 databases. These secondary analyses have confirmed: (a) the importance of the predictive power of ESCS on performance consistently in both 2015 and 2022; (b) the intensification of the association between the two variables in that period; and (c) the emergence of a moderate but significant association of the language variable as a predictor of Performance at the territorial level. The impact of regional ESCS differences on performance increased significantly between 2015 and 2022, which is compatible with an increase in other territorial divides described in the literature. Moreover, the strong linguistic immersion models display significant differences between territories in terms of performance. For example, for this reason alone, Catalonia’s delay compared to Madrid is approximately one school year.
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- 2024
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47. Effectiveness of a hybrid closed-loop system for children and adolescents with type 1 diabetes during physical exercise: A cross-sectional study in real life
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Ruben Martin-Payo, Maria del Mar Fernandez-Alvarez, Rebeca García-García, Ángela Pérez-Varela, Shelini Surendran, and Isolina Riaño-Galán
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Adolescentes ,Niños ,Ejercicio ,Pediatría ,Diabetes tipo 1 ,Pediatrics ,RJ1-570 - Abstract
Objective: The aim of the study was to describe how physical exercise affects metabolic control, insulin requirements and carbohydrate intake in children who use hybrid closed-loop systems. Methods: Cross-sectional study design. The sample included 21 children and adolescents diagnosed with type 1 diabetes. During the study, participants were monitored for a period of 7 days to gather comprehensive data on these factors. Results: Nine participants (42.9%) had switched to exercise mode to raise the target glucose temporarily to 150 mg/dL. The HbA1c values ranged from 5.5% to 7.9% (median, 6.5%; IQR, 0.75). The percentage of time within the target range of 70−180 mg/dL was similar; however, there was an increased duration of hyperglycaemia and more autocorrections on exercise days. The time spent in severe hyperglycaemia (>250 mg/dL) increased by 2.7% in exercise compared to non-exercise days (P = .02). It is worth noting that hypoglycaemic episodes did not increase during the exercise days compared with non-exercise days. Conclusion: The hybrid closed-loop system was effective and safe in children and adolescents with type 1 diabetes during the performance of competitive sports in real life. Resumen: Objetivo: El objetivo de este estudio es describir cómo el ejercicio físico afecta el control metabólico, las necesidades de insulina y el consumo de carbohidratos en niños usuarios de un sistema híbrido de circuito cerrado. Métodos: Diseño de estudio transversal. Se reclutaron veintiún niños y adolescentes diagnosticados con diabetes tipo 1. Durante el estudio, los participantes fueron monitoreados durante un período de 7 días para recopilar datos completos sobre estos factores. Resultados: Nueve participantes (42,9%) habían activado el modo de ejercicio, para elevar temporalmente la glucosa objetivo a 150 mg/dL. La HbA1c osciló entre 5,5% y 7,9% (mediana 6,5%, IQR 0,75). El porcentaje de tiempo dentro del rango de 70−180 mg/dL fue similar; sin embargo, hubo una mayor duración de la hiperglucemia y más autocorrecciones en los días en que se realizó ejercicio. El porcentaje de tiempo en hiperglucemia grave (>250 mg/dL) fue 2,7 mayor durante el ejercicio versus los días sin ejercicio (p = 0,02). En particular, los episodios de hipoglucemia no aumentaron durante los días de práctica de ejercicio, en comparación con los días sin ejercicio. Conclusiones: El sistema híbrido de circuito cerrado fue efectivo y seguro en niños y adolescentes diagnosticados con diabetes tipo 1 durante ejercicios físicos competitivos en la vida real.
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- 2024
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48. Traumatismos periféricos atendidos en el Servicio de Urgencias Pediátricas. Estudio descriptivo
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S. Suarez-Cabezas, E. Sanavia Morán, A. García García-Galán, A.T. Álvarez Sánchez, C. Muñoz López, and B. Pérez-Moneo Agapito
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Trauma ,Injuries ,Emergencies ,Radiography ,Orthopedic surgery ,RD701-811 - Abstract
Resumen: Introducción: Los traumatismos periféricos son una causa muy frecuente de consulta en las urgencias pediátricas, pero apenas se han publicado estudios que describan las características de estos pacientes. Material y métodos: Se realiza un estudio descriptivo retrospectivo mediante revisión de formularios informatizados de urgencias pediátricas durante los meses de enero y febrero de 2020. Objetivo: Conocer las características de la patología traumática pediátrica de nuestra área y detectar posibles puntos de mejora. Resultados: Se atendieron 714 traumatismos periféricos, lo que supone 9,5% de las consultas totales. De los pacientes presentados, 52,7% fueron escolares (6 a 11 años). Las localizaciones más frecuentes fueron el tobillo (27,5%) y los dedos de la mano (17,2%). Se detectó fractura en 6,7% de los casos. En 78,6% de los pacientes se solicitó radiografía, siendo patológica 9,6% de las mismas. La mitad de las radiografías se solicitaron por traumatismo en el tobillo o dedos de la mano. Se realizó interconsulta a traumatología en 16,4% de los pacientes, sobre todo en traumatismos de codo y rodilla, y el tratamiento más empleado fueron las medidas generales (49%) y el vendaje (29,4%). Conclusiones: Los traumatismos periféricos son muy habituales y, en general, banales. Se solicita un gran número de radiografías con una rentabilidad muy baja, por lo que parece necesario establecer nuevos protocolos que permitan reducir el número de peticiones. Mejorar la formación respecto a los traumatismos de codo y rodilla podría mejorar la autonomía de los pediatras respecto a este tipo de lesiones, más complejas. Abstract: Introduction: Peripheral trauma is a very frequent cause of consultation in paediatric emergency departments but few studies have been published describing the characteristics of these patients. Material and methods: We performed a retrospective descriptive study by reviewing computerised emergency department forms during January and February 2020. Objective: To describe the characteristics of traumatic injuries in our area and to detect possible areas for improvement. Results: A total of 714 peripheral trauma cases were attended, which represents 9.5% of the total consultations. A total of 52.7% were schoolchildren (6–11 years). The most frequent locations were the ankle (27.5%) and fingers (17.2%). Fracture was detected in 6.7% of cases. Radiographs were requested in 78.6% of the patients, with pathological findings in 9.6% of them. Half of the X-rays were requested due to ankle or finger trauma. Referral to traumatology was made in 16.4% of patients, mainly for elbow and knee trauma, and the most commonly used treatment was general measures (49%) and bandaging (29.4%). Conclusions: Peripheral trauma is very common and, in general, banal. A large number of X-rays are requested with a very low yield, so it seems necessary to establish new protocols to reduce the number of requests. Improving training in elbow and knee trauma could improve paediatricians’ autonomy in dealing with these more complex injuries.
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- 2024
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49. Enhanced Mortality Prediction In Patients With Subarachnoid Haemorrhage Using A Deep Learning Model Based On The Initial CT Scan
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Garcia-Garcia, Sergio, Cepeda, Santiago, Muller, Dominik, Mosteiro, Alejandra, Torne, Ramon, Agudo, Silvia, de la Torre, Natalia, Arrese, Ignacio, and Sarabia, Rosario
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Statistics - Machine Learning - Abstract
PURPOSE: Subarachnoid hemorrhage (SAH) entails high morbidity and mortality rates. Convolutional neural networks (CNN), a form of deep learning, are capable of generating highly accurate predictions from imaging data. Our objective was to predict mortality in SAH patients by processing the initial CT scan on a CNN based algorithm. METHODS: Retrospective multicentric study of a consecutive cohort of patients with SAH between 2011-2022. Demographic, clinical and radiological variables were analyzed. Pre-processed baseline CT scan images were used as the input for training a CNN using AUCMEDI Framework. Our model's architecture leverages the DenseNet-121 structure, employing transfer learning principles. The output variable was mortality in the first three months. Performance of the model was evaluated by statistical parameters conventionally used in studies involving artificial intelligence methods. RESULTS: Images from 219 patients were processed, 175 for training and validation of the CNN and 44 for its evaluation. 52%(115/219) of patients were female, and the median age was 58(SD=13.06) years. 18.5%(39/219) were idiopathic SAH. Mortality rate was 28.5%(63/219). The model showed good accuracy at predicting mortality in SAH patients exclusively using the images of the initial CT scan (Accuracy=74%, F1=75% and AUC=82%). CONCLUSION: Modern image processing techniques based on AI and CNN make possible to predict mortality in SAH patients with high accuracy using CT scan images as the only input. These models might be optimized by including more data and patients resulting in better training, development and performance on tasks which are beyond the skills of conventional clinical knowledge.
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- 2023
50. Galaxy bias in the era of LSST: perturbative bias expansions
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Nicola, Andrina, Hadzhiyska, Boryana, Findlay, Nathan, García-García, Carlos, Alonso, David, Slosar, Anže, Guo, Zhiyuan, Kokron, Nickolas, Angulo, Raúl, Aviles, Alejandro, Blazek, Jonathan, Dunkley, Jo, Jain, Bhuvnesh, Pellejero, Marcos, Sullivan, James, Walter, Christopher W., and Zennaro, Matteo
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Upcoming imaging surveys will allow for high signal-to-noise measurements of galaxy clustering at small scales. In this work, we present the results of the LSST bias challenge, the goal of which is to compare the performance of different nonlinear galaxy bias models in the context of LSST Y10 data. Specifically, we compare two perturbative approaches, Lagrangian perturbation theory (LPT) and Eulerian PT (EPT) to two variants of Hybrid Effective Field Theory (HEFT), with our fiducial implementation of these models including terms up to second order in the bias expansion as well as nonlocal bias and deviations from Poissonian stochasticity. We consider different simulated galaxy samples and test the performance of the bias models in a tomographic joint analysis of LSST-Y10-like galaxy clustering, galaxy-galaxy-lensing and cosmic shear. We find both HEFT methods as well as LPT and EPT combined with non-perturbative predictions for the matter power spectrum to yield unbiased constraints on cosmological parameters up to at least a maximal scale of $k_{\mathrm{max}}=0.4 \; \mathrm{Mpc}^{-1}$ for all samples considered, even in the presence of assembly bias. While we find that we can reduce the complexity of the bias model for HEFT without compromising fit accuracy, this is not generally the case for the perturbative models. We find significant detections of non-Poissonian stochasticity in all cases considered, and our analysis shows evidence that small-scale galaxy clustering predominantly improves constraints on galaxy bias rather than cosmological parameters. These results therefore suggest that the systematic uncertainties associated with current nonlinear bias models are likely to be subdominant compared to other sources of error for tomographic analyses of upcoming photometric surveys, which bodes well for future galaxy clustering analyses using these high signal-to-noise data. [abridged], Comment: 47 pages, 19 figures, 1 table, to be submitted to JCAP
- Published
- 2023
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