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25 results on '"García-Conde Bru J"'

2. p29 protein in breast cancer: relation between estrogen and progesterone receptors

Author

Alberola Candel, Bueno Cañigral Fj, Martin Quetglas G, Lluch Hernandez A, Artero Morà A, García-Conde Bru J, and Cano Sanchez A

Subjects
Adult, Cancer Research, medicine.medical_specialty, medicine.drug_class, Estrogen receptor, Breast Neoplasms, 030218 nuclear medicine & medical imaging, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, Progesterone receptor, medicine, Humans, Estrogen receptor beta, Aged, Aged, 80 and over, business.industry, General Medicine, Middle Aged, medicine.disease, Phosphoproteins, Primary tumor, Endocrinology, Oncology, Receptors, Estrogen, Estrogen, 030220 oncology & carcinogenesis, Lymphatic Metastasis, Female, Menopause, business, Receptors, Progesterone, Estrogen receptor alpha
Abstract

An immunoradiometric assay was used to determine the presence of p29 protein in 68 breast cancer cytosols. The p29 values ranged from 0 to 1123 U/mg, with a mean value of 127+28.7 U/mg. Using a cutoff point of 20 U/mg the frequency of p29 positive tumors was about 55%. A quantitative and qualitative relation was found between p29 and estrogen receptor (ER), but not between p29 and progesterone receptor (PR). Discordance between p29 and ER status was found in 13 out of 68 tumors. Both the frequency of p29 positive tumors and the p29 values were significantly higher in postmenopausal than in premenopausal women, in a similar way to ER but different from PR. There was no difference in p29 content between primary tumor and metastasis. We did not find any relation among p29 primary tumors content and axillary lymph nodes involvement or tumor size.

Published
1989

3. [Serum ferritin in chronic hepatopathies. Study of its significance]

Author

Carlos Camps, Alberola V, Labios M, Aranda M, Domínguez C, and García-Conde Bru J

Subjects
Adult, Male, Anemia, Hypochromic, Adolescent, Liver Diseases, Anemia, Hemorrhage, Middle Aged, Hypersplenism, Sex Factors, Chronic Disease, Ferritins, Humans, Female, Aged
Published
1986

7. [Epithelioid angiomatosis and HIV infection. A neoplastic or infectious proliferative disease?].

Author

Aguilar Ligorit E, Sánchez Fernández de Sevilla C, Guix García J, Llombart Bosch A, and García-Conde Bru J

Subjects
Acquired Immunodeficiency Syndrome complications, Acquired Immunodeficiency Syndrome diagnosis, Acquired Immunodeficiency Syndrome pathology, Adult, Angiomatosis diagnosis, Angiomatosis pathology, HIV Infections diagnosis, HIV Infections pathology, HIV Seropositivity complications, HIV Seropositivity pathology, Homosexuality, Humans, Male, Neurosyphilis complications, Neurosyphilis pathology, Skin pathology, Skin Neoplasms pathology, Angiomatosis complications, HIV Infections complications, HIV-1, Skin Neoplasms diagnosis
Abstract

A case of "epithelioid angiomatosis" detected in a homosexual patient with positive seric HIV is presented. The skin lesions cytoplasm rich, closed y clumped together, with scanty stromal compound. Warthin-Starry staining [correction of tintions] did not show Bacillus causing "cat scratch disease". We review and analyse the features of this type of proliferation in patients infected with HIV.

Published
1990

8. [Syndrome of persistent generalized lymphadenopathy with development into a gastric lymphoma].

Author

Aguilar Ligorit E, Guix García J, Escrig Orenga V, Benet Monforte I, and García-Conde Bru J

Subjects
Adult, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Bleomycin administration & dosage, Cyclophosphamide administration & dosage, Dexamethasone administration & dosage, Doxorubicin administration & dosage, Humans, Leucovorin administration & dosage, Lymphoma, Non-Hodgkin drug therapy, Male, Methotrexate administration & dosage, Opportunistic Infections complications, Stomach Neoplasms drug therapy, Substance-Related Disorders complications, Tuberculosis, Miliary complications, Vincristine administration & dosage, AIDS-Related Complex complications, Lymphoma, Non-Hodgkin etiology, Stomach Neoplasms etiology
Abstract

A man with previous addiction to parenteral drugs presented infection by human immunodeficiency virus (HIV) with persistent generalised lymph node enlargement. Sixteen months after diagnosis, he developed intermediate-grade lymphoma of the stomach. Partial response was achieved by chemotherapy, and the patient presented pulmonary and meningeal tuberculosis which led him to exitus.

Published
1990

9. [Syndrome of persistent generalized lymphadenopathies parenteral drug addicts. Clinical, immunological and histopathological study of 18 cases].

Author

Aguilar Ligorit E, Guix García J, Sánchez Fernández de Sevilla C, Escrig Orenga V, Alberola Candel V, Llombart Bosch A, and García-Conde Bru J

Subjects
Adolescent, Adult, Female, Humans, Immunity, Cellular, Injections, Intramuscular, Male, AIDS-Related Complex blood, AIDS-Related Complex complications, AIDS-Related Complex immunology, AIDS-Related Complex pathology, Substance-Related Disorders complications
Published
1988

10. [Thrombopenic purpura in a group of addicts addicted to parenteral drugs with anti-HTLV-III/LAV antibodies and inversion of the T-helper/T-suppressor cell quotient].

Author

Aguilar Ligorti E, Guix García J, Ample Guillén I, Balaguer Martínez JV, Marugán de la Concha I, and García-Conde Bru J

Subjects
Adult, Female, Humans, Male, Purpura, Thrombocytopenic blood, Substance-Related Disorders immunology, Antibodies, Viral immunology, HIV immunology, Purpura, Thrombocytopenic immunology, Substance-Related Disorders complications, T-Lymphocytes, Helper-Inducer immunology, T-Lymphocytes, Regulatory immunology
Published
1986

11. [Fibrinopeptide A in cancer patients and its changes with chemotherapy].

Author

Ruiz Guinaldo MA, Marugán de la Concha I, Navarro Gonzalo I, and García-Conde Bru J

Subjects
Adult, Anticoagulants therapeutic use, Antineoplastic Combined Chemotherapy Protocols adverse effects, Blood Coagulation Disorders drug therapy, Blood Coagulation Disorders etiology, Female, Humans, Male, Middle Aged, Neoplasms complications, Neoplasms drug therapy, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Fibrinogen analysis, Fibrinopeptide A analysis, Neoplasms blood
Published
1985

12. [Changes in immunity in parenteral drug addicts].

Author

Aquilar Ligorit E, Guix García J, Alberola Candell V, and García-Conde Bru J

Subjects
Adolescent, Adult, Antibody Formation, Female, Humans, Immunity, Cellular, Male, Substance-Related Disorders immunology
Published
1986

14. [Serum ferritin in chronic hepatopathies. Study of its significance].

Author

Camps C, Alberola V, Labios M, Aranda M, Domínguez C, and García-Conde Bru J

Subjects
Adolescent, Adult, Aged, Anemia blood, Anemia etiology, Anemia, Hypochromic blood, Anemia, Hypochromic etiology, Chronic Disease, Female, Hemorrhage complications, Humans, Hypersplenism complications, Liver Diseases complications, Male, Middle Aged, Sex Factors, Ferritins blood, Liver Diseases blood
Published
1986

15. [Pathogenetic mechanisms of platelet hyperaggregation in diabetics (author's transl)].

Author

Amado Señars JA, García-Conde Bru J, Merino Sánchez J, and Benet Monforte I

Subjects
Animals, Blood Platelets metabolism, Creatine Kinase metabolism, Diabetes Mellitus metabolism, Diabetic Retinopathy blood, Diabetic Retinopathy metabolism, Epoprostenol pharmacology, Ethanol pharmacology, Humans, Imidazoles pharmacology, Phosphocreatine metabolism, Rats, Arachidonic Acids pharmacology, Diabetes Mellitus blood, Platelet Aggregation drug effects
Published
1981

16. [Thrombopenic purpura associated with human immunodeficiency virus infection. Analysis of 24 cases].

Author

Aguilar Ligorit E, Guix García J, Benet Monforte I, Marugán de la Concha I, Escrig Orenga V, Pascual López A, Alberola Candel V, and García-Conde Bru J

Subjects
Acquired Immunodeficiency Syndrome diagnosis, Adult, Female, Follow-Up Studies, Humans, Male, Plasma Exchange, Prednisone therapeutic use, Purpura, Thrombocytopenic diagnosis, Purpura, Thrombocytopenic therapy, Time Factors, Vincristine therapeutic use, Acquired Immunodeficiency Syndrome complications, Purpura, Thrombocytopenic complications
Abstract

In 24 cases of thrombopenic purpura associated with human immunodeficiency virus infection the clinical, immunological and therapeutic features were evaluated. Thrombopenia resulted in clinical manifestations in 20 patients. Splenomegaly was found in only one fourth of patients. Antiplatelet antibodies were found in 9 patients, and thrombopenia was associated with anemia in 37% of cases and with leukopenia in 21%. Bone marrow examination showed megakaryocyte hyperplasia in two thirds of the patients. The major immunological abnormalities were an inverted helper/suppressor T lymphocytes ratio, a reduction in the number of helper T lymphocytes, polyclonal hypergammaglobulinemia, and increased serum concentrations of circulating immunocomplexes. The different therapeutic modalities, steroids, vincristine, danatrol and plasma exchange, resulted in short responses; only two patients had normal platelet counts. The median follow-up was 14 months; during this time three patients fulfilled the criteria of acquired immunodeficiency syndrome.

Published
1989

17. [Blood cell counts in parenteral drug addicts].

Author

Aguilar Ligorit E, Guix García J, Ample Guillén I, Escrig Orenga V, Pascual López A, Alberola Candel V, and García-Conde Bru J

Subjects
Adolescent, Adult, Antibodies, Viral analysis, Erythrocyte Count, Female, HIV immunology, Humans, Male, Substance-Related Disorders immunology, Blood Cell Count, Substance-Related Disorders blood
Published
1987

18. [Case of multiple endocrine neoplasia type II-b].

Author

Alcacer García F, Alonso Salvador MD, Ballester Belenguer J, Bort Martí J, Ruiz Castillo J, Carbonell Antolí C, and García Conde-Bru J

Subjects
Adult, Female, Humans, Adrenal Gland Neoplasms pathology, Carcinoma pathology, Multiple Endocrine Neoplasia pathology, Neurofibroma pathology, Pheochromocytoma pathology, Thyroid Neoplasms pathology
Published
1982

20. [Cloxacillin-induced neutropenia].

Author

Aguilar Ligorit E, Gómez Codina J, Guix García J, and García-Conde Bru J

Subjects
Adult, Bone Marrow Examination, Humans, Male, Neutropenia diagnosis, Agranulocytosis chemically induced, Cloxacillin adverse effects, Neutropenia chemically induced
Published
1988

21. [Applications of endoscopy in cancer of the esophagus].

Author

Alegre Martínez J, Ferrando Cucarella J, Villar R, and García-Conde Bru J

Subjects
Biopsy, Esophageal Diseases pathology, Esophageal Neoplasms pathology, Esophageal Neoplasms therapy, Esophagus pathology, Humans, Neoplasm Recurrence, Local diagnosis, Precancerous Conditions pathology, Esophageal Diseases diagnosis, Esophageal Neoplasms diagnosis, Esophagoscopy, Precancerous Conditions diagnosis
Published
1985

22. [Activity of total complement and concentration of its components C1q, C3, C4 and C1-inactivator in cancer].

Author

Matoses Cuquerella S, O'Connor Miquel C, Lluch Hernández AM, and García-Conde Bru J

Subjects
Adult, Aged, Breast Neoplasms therapy, Complement C1q, Female, Humans, Middle Aged, Neoplasm Metastasis, Breast Neoplasms immunology, Complement Activating Enzymes analysis, Complement C1 analysis, Complement C1 Inactivator Proteins analysis, Complement C3 analysis, Complement C4 analysis, Complement System Proteins analysis
Published
1988

24. [Action of phenylbutazone on platelet function].

Author

García-Conde Bru J, Díaz Mayo MC, and Benet Monforte IA

Subjects
Adult, Blood Coagulation drug effects, Female, Fibrinolysis drug effects, Humans, Male, Middle Aged, Platelet Adhesiveness drug effects, Blood Platelets drug effects, Phenylbutazone pharmacology
Published
1970

25. [Prevention and treatment of accidents caused by iodinated contrast media].

Author

Valle Sánchiz J, Chuliá Campos V, Marugán Gómez I, and García-Conde Bru J

Subjects
Adolescent, Adult, Aged, Blood Coagulation drug effects, Fibrinolysis drug effects, Humans, Middle Aged, Contrast Media adverse effects, Drug Hypersensitivity, Iodides adverse effects
Published
1972

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