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8. Antibiotic use and outcome in patients with negative blood cultures, a new target population for antimicrobial stewardship interventions: A prospective multicentre cohort (NO-BACT)

Author

Girón-Ortega, José Antonio, Fernández-Guerrero, Raquel, de Oca Arjona, Montserrat Montes, Galán-Sanchez, Fátima, Sagastizábal, Galadriel Pellejero, Romea, Elena Morte, de Cueto, Marina, Garcia, Margarita Beltrán, Palacios-Baena, Zaira, Jorge, Silvia Jiménez, Rodríguez-Baño, Jesús, and Retamar-Gentil, Pilar

Published
2024
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15. Delayed bilateral blindness after methanol poisoning

Author

García Rodríguez, Alen, primary, Amaro León, María Isabel, additional, Alvisa Negrín, Julio César, additional, Martín González, Candelaria, additional, Fuentes García, Margarita, additional, Valderrey Pulido, Javier, additional, and Guerrero Martir, Martín, additional

Published
2024
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17. Effect of UV-C disinfection and copper plating on healthcare-associated infections in a NICU with high ESBL infections

Author

de la Rosa-Zamboni, Daniela, primary, Villa-Guillén, Mónica, additional, Bustos-Hamdan, Anaíd, additional, Rosas-Mateos, María Isabel, additional, Medina-Pelcastre, Marisol, additional, Torres-García, Margarita, additional, Franco-Hernández, María Isabel, additional, del Carmen Castellanos-Cruz, María, additional, Parra-Ortega, Israel, additional, Fest-Parra, Edmedt, additional, Casillas-Casillas, María Citlalli, additional, and Guerrero-Díaz, Ana Carmen, additional

Published
2024
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23. Antibiotic use and outcome in patients with negative blood cultures, a new target population for antimicrobial stewardship interventions: A prospective multicentre cohort (NO-BACT)

Author

European Commission, Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Red Española de Investigación en Patología Infecciosa, Girón-Ortega, José Antonio, Fernández-Guerrero, Raquel, Montes de Oca Arjona, Montserrat, Galán-Sánchez, Fátima, Sagastizábal, Galadriel Pellejero, Morte-Romea, Elena, Cueto, Marina de, Beltrán-García, Margarita, Palacios-Baena, Zaira, Jiménez-Jorge, Silvia, Rodríguez-Baño, Jesús, Retamar-Gentil, Pilar, European Commission, Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Red Española de Investigación en Patología Infecciosa, Girón-Ortega, José Antonio, Fernández-Guerrero, Raquel, Montes de Oca Arjona, Montserrat, Galán-Sánchez, Fátima, Sagastizábal, Galadriel Pellejero, Morte-Romea, Elena, Cueto, Marina de, Beltrán-García, Margarita, Palacios-Baena, Zaira, Jiménez-Jorge, Silvia, Rodríguez-Baño, Jesús, and Retamar-Gentil, Pilar

Abstract

[Objectives] To evaluate the appropriateness of antimicrobial treatment and the risk factors for mortality in patients with negative blood cultures (BC), in order to evaluate whether this population would be a suitable target for antimicrobial stewardship (AMS) interventions., [Methods] A multicentre prospective cohort study of patients with negative BC in three Spanish hospitals between October 2018 and July 2019 was performed. The main endpoints were the appropriateness of antimicrobial treatment (evaluated by two investigators according to local guidelines) and 30-day mortality. Cox-regression was performed to estimate the association between variables and 30-day mortality., [Results] Of 1011 patients in whom BC was obtained, these were negative in 803 (79%) and were included; 30-day mortality was 9% (70 patients); antibiotic treatment was considered inappropriate in 299 (40%) of 747 patients evaluated at day 2, and in 266 (46%) of 573 at day 5–7. The variables independently associated with increased risk of 30-day mortality were higher age (HR 1.05; 95% CI 1.03–1.07), neoplasia (HR 2.73; 95% CI 1.64–4.56), antibiotic treatment in the 48 h prior to BC extraction (HR 2.06; 95% CI 1.23–3.43) and insufficient antibiotic coverage at day 2 after BC obtainment (HR 2.35; 95% CI 1.39–4.00). Urinary, catheter and biliary sources of infection were associated with lower risk (HR 0.40; 95% CI 0.20–0.81)., [Conclusions] Antimicrobial treatment is frequently inappropriate among patients with negative BC; insufficient antibiotic coverage at day 2 was associated with mortality. These results suggest that patients with negative BC are a suitable population for AS interventions., [Summary] Antimicrobial treatment in patients with negative blood culture was frequently inappropriate, and inappropriate coverage at day 2 was associated with increased risk of death. These data support the consideration of this population as a potential target for antimicrobial stewardship interventions.

Published
2024

24. Sovereign bond spreads and CDS premia in the Eurozone: A causality analysis || Diferenciales de bonos soberanos y primas de CDS en la zona euro: un análisis de causalidad

Author

Téllez Valle, Cecilia, Martín García, Margarita, Ramón-Jerónimo, María A., and Martín Marín, José Luis

Subjects
sovereign risk, credit risk, cds, causality, riesgo soberano, riesgo de crédito, causalidad, Applied mathematics. Quantitative methods, T57-57.97, Mathematics, QA1-939, Business, HF5001-6182
Abstract

This article presents an analysis of the possible relationship between the spreads of sovereign bonds and the premia of credit default swaps (CDS) to determine whether they are useful tools for the measurement of the sovereign risk either separately or by taking into account the joint evolution of their values. The data refer to ten countries in the Eurozone along 2008–2016. By applying the causality Granger test for these variables, after six different ways of proxy, CDS premia are found to be the cause of the risk spreads in certain cases, although a bidirectional relationship is predominant in many other cases. So the CDS market contains clear and highly useful information on the sovereign risk. || Este artículo presenta un análisis de la posible relación existente entre los diferenciales de los bonos soberanos y las primas de las permutas financieras de riesgo de impago (CDS, Credit Default Swap), con el objeto de determinar si son herramientas útiles para la medida del riesgo soberano de forma separada o teniendo en cuenta ambas variables. Se toman datos de 10 países de la Eurozona para el periodo 2008-2016. Aplicando el test de causalidad de Granger para esas variables, después de utilizar seis formas distintas de comparación de diferenciales, se concluye que la prima del CDS causa el diferencial de riesgo de crédito en suficientes ocasiones, aunque predomina una relación bidireccional. Así que el mercado de CDS contiene información clara y útil para la evolución del riesgo soberano.

Published
2020
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36. The Response of Naturally Based Coatings and Citrus Fungicides to the Development of Four Postharvest Fungi.

Author

Serrano-Molina, Lizette, Hernández-López, Mónica, Salazar-Piña, Dolores Azucena, Bautista-Baños, Silvia, and Ramos-García, Margarita de Lorena

Subjects
FUNGICIDES, COLLETOTRICHUM gloeosporioides, ORANGES, CITRUS, ASPERGILLUS flavus, SURFACE coatings
Abstract

The tomato (Licopersicon esculentum Mill.) is considered to be one of the products with the highest demand due to its nutritional value; however, it is susceptible to infection by fungi during its pre- and postharvest stages. In this research, three commercial products (1% Citrocover, 1% Citro 80, and 0.002% Microdyn) and two coatings based on 1.0% chitosan/0.1% lime or 0.1% orange essential oils were evaluated in vitro and on Saladette tomatoes that were previously inoculated with four postharvest fungi. The application of the commercial citrus-based product Citrocover was highly effective in reducing the in vitro development of Aspergillus flavus, Fusarium oxysporum, and Colletotrichum gloeosporioides, but not Rhizopus stolonifer. The sanitizer Microdyn promoted infections with most fungi. Citrus-based products were effective in reducing infections with A. flavus in the tomatoes during storage. Overall, mycotoxin production was very low for all treatments. The use of commercial citrus-based products and coatings did not alter the weight loss, firmness, or total soluble solid contents of the treated tomatoes. The changes observed were, rather, associated with the normal ripening process of Saladette tomatoes. The commercial citrus-based products satisfactorily controlled the in vitro growth of the fungi Aspergillus flavus, Fusarium oxysporum, and Colletotrichum gloeosporioides. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Reducing CLABSI through a quality strategy for the implementation of the aseptic non-touch technique in a pediatric ward.

Author

Guerrero-Díaz, Ana C., De la Rosa-Zamboni, Daniela, Martin-Martin, Ma. A., Rosas-Mateos, Isabel, Medina-Pelcastre, Marisol, Torres-García, Margarita, Laris-González, Almudena, and Avilés-Robles, Martha

Subjects
CENTRAL line-associated bloodstream infections, INFECTION in children, EPIDEMIOLOGY, NURSE training, CHILDREN'S hospitals
Abstract

Copyright of Boletín Médico del Hospital Infantil de México is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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38. Inteligencia artificial y nuevas formas de derecho en el siglo XXI.

Author

Villasmil Espinoza, Jorge Jesús, Berrocal Duran, Juan Carlos, and Rodelo García, Margarita Rosa

Abstract

Copyright of Revista de Ciencias Sociales (13159518) is the property of Revista de Ciencias Sociales de la Universidad del Zulia Venezuela and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

39. Hepatic Steatosis and Weight Gain During the Coronavirus Disease 2019 Pandemic Among People With Human Immunodeficiency Virus: Impact of Therapy With Tenofovir Alafenamide

Author

Santos, Marta, primary, Corma-Gómez, Anais, additional, Martin-Carmona, Jesica, additional, Pérez-García, Margarita, additional, Martín-Sierra, Carmen, additional, Rincón-Mayo, Pilar, additional, González-Serna, Alejandro, additional, Pineda, Juan Antonio, additional, Real, Luis Miguel, additional, and Macías, Juan, additional

Published
2023
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