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1,164 results on '"García, Gloria"'

6. $\gamma$ rays run on time

Author

Martínez, Daniel Beltrán, Llanes-Estrada, Felipe J., and Tejedor-García, Gloria

Subjects
Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract

Significant absorption of radiation is usually accompanied by refraction. This is not the case for $\gamma$ rays travelling cosmic distances. We show that the real and imaginary parts of the refraction index are indeed commensurable, as they are related by dispersion relations, but when turning to physical observables, the (finite) optical depth is way larger than the (infinitesimal) time delay of the gamma rays relative to gravitational radiation. The numerically large factor solving the apparent contradiction is $E_\gamma/H_0$ arising from basic wave properties (Bouguer-Beer-Lambert law) and the standard cosmological model, respectively., Comment: 11 pages containing 9 plots

Published
2022
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8. The Use of Logical Implication as an Indicator of Understanding the Concept of Number Sequences

Author

Bajo-Benito, José Mariano, Sánchez-Matamoros García, Gloria, and Gavilán-Izquierdo, José María

Abstract

This paper aims to characterise an indicator of the development of the number sequence scheme among students at the level of Compulsory Secondary Education (14-16 years old students). To do so, we use a scheme development proposed by the APOS theory to characterise students' use of relations between mathematical elements when solving a mathematical task. We use a qualitative methodology and the data collection instruments are a written questionnaire and a semi-structured interview. In this work we show the questionnaire task that provides analytical expressions and ask students to determine which of them numbers sequences are. We find that students' use of logical implication when solving tasks related to number sequences is an indicator of the development of the scheme. This indicator helps to locate the transition mechanisms between the levels of development of the number sequence scheme. Moreover, our research shows that arithmetic and geometric progressions play a key role as an indicator of the development of the number sequence scheme.

Published
2021

11. A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects.

Author

Acosta-Uribe, Juliana, Aguillón, David, Cochran, J, Giraldo, Margarita, Madrigal, Lucía, Killingsworth, Bradley, Singhal, Rijul, Labib, Sarah, Alzate, Diana, Velilla, Lina, Moreno, Sonia, García, Gloria, Saldarriaga, Amanda, Piedrahita, Francisco, Hincapié, Liliana, López, Hugo, Perumal, Nithesh, Morelo, Leonilde, Vallejo, Dionis, Solano, Juan, Reiman, Eric, Surace, Ezequiel, Itzcovich, Tatiana, Allegri, Ricardo, Sánchez-Valle, Raquel, Villegas-Lanau, Andrés, White, Charles, Matallana, Diana, Myers, Richard, Browning, Sharon, Lopera, Francisco, and Kosik, Kenneth

Subjects
Admixture, Alzheimer’s disease, Bottleneck, Demography, Founder effect, Frontotemporal dementia, Genetic drift, Motor neuron disease, Neurodegeneration, Selection, Alzheimer Disease, Colombia, Founder Effect, Frontotemporal Lobar Degeneration, Humans, Mutation, Neurodegenerative Diseases
Abstract

BACKGROUND: The Colombian population, as well as those in other Latin American regions, arose from a recent tri-continental admixture among Native Americans, Spanish invaders, and enslaved Africans, all of whom passed through a population bottleneck due to widespread infectious diseases that left small isolated local settlements. As a result, the current population reflects multiple founder effects derived from diverse ancestries. METHODS: We characterized the role of admixture and founder effects on the origination of the mutational landscape that led to neurodegenerative disorders under these historical circumstances. Genomes from 900 Colombian individuals with Alzheimers disease (AD) [n = 376], frontotemporal lobar degeneration-motor neuron disease continuum (FTLD-MND) [n = 197], early-onset dementia not otherwise specified (EOD) [n = 73], and healthy participants [n = 254] were analyzed. We examined their global and local ancestry proportions and screened this cohort for deleterious variants in disease-causing and risk-conferring genes. RESULTS: We identified 21 pathogenic variants in AD-FTLD related genes, and PSEN1 harbored the majority (11 pathogenic variants). Variants were identified from all three continental ancestries. TREM2 heterozygous and homozygous variants were the most common among AD risk genes (102 carriers), a point of interest because the disease risk conferred by these variants differed according to ancestry. Several gene variants that have a known association with MND in European populations had FTLD phenotypes on a Native American haplotype. Consistent with founder effects, identity by descent among carriers of the same variant was frequent. CONCLUSIONS: Colombian demography with multiple mini-bottlenecks probably enhanced the detection of founder events and left a proportionally higher frequency of rare variants derived from the ancestral populations. These findings demonstrate the role of genomically defined ancestry in phenotypic disease expression, a phenotypic range of different rare mutations in the same gene, and further emphasize the importance of inclusiveness in genetic studies.

Published
2022

13. Immunogenicity and safety assessment of a SARS-CoV-2 recombinant spike RBD protein vaccine (Abdala) in paediatric ages 3–18 years old: a double-blinded, multicentre, randomised, phase 1/2 clinical trial (ISMAELILLO study)

Author

López-Machado, M.A., Rodriguez, D Alonso, Basulto-Puig, J.C., Martin-Hernandez, T., Sánchez-Miranda, D., Agüero-Betancourt, C.M., Besú-García, B., Rodríguez-Fernández, Y., Guerrero-Vega, L., GómezFonseca, I., Ramos-Pérez, O., Acosta-Domínguez, I., Ronquillo-Ramirez, D., Díaz-Fernández, Y., Aguilar-Soto, L., Reíd-Montejo, J., Palomo-Leyva, Y., LandinFaria, M.R., Rosendo-Domínguez, R.M., Alonso-Manresa, C., Marín-Pérez, D.M., Malo-Lantigua, Y., Rodríguez-Florat, M.C., Delgado-Laborit, Y., RodriguezGuevara, Y., Peláez-González, M., Torres-Mora, Y., Cabrera-Hernández, O.S., Gimarais-Varona, F.J., Hormigot-Hernández, M., Artola-Gutiérrez, L.V., Gallardo-Martí, L., Porro-Verdecia, J., Castro-Bistorte, R., RobertsDandie, E., Berenguer-Pedroso, S., Manso-García, Yudith, Mora-García, C.V., Lastre-Muñoz, Y., Duran-Rivero, O., Hernández-García, B., Escobar-Escobar, K., CarmenatesGutiérrez, M.K., Conde-Bello, B., Olazabal-Linares, E.L., Bringas-Labrada, I., Noy-León, M., Velazco-González, N., Bursosa-Moreno, B., Morell-Padrón, Y., Rodríguez-Matos, Y., Treto-Torguet, Y.M., Comas-Díaz, L., Miranda, F., FigueredoGonzález, Y., Quiñones-Juan, A., Mursuli-García, I., Giménez-Velásquez, V.M., Hernández-Ávila, A., Hernández-Cabrera, T., García-Zulueta, T., Parra-Pérez, A., Cintra-Jacob, D., Mendoza-Jiménez, M., de la Fuente-Carbonell, S.M., Hernández-Eduard, B., Ochoa-García, M., Garcia-Iglesias, E., Álvarez-Acosta, A., Martínez-Rosales, R.U., Ávila-Díaz, L., Santana-Vázquez, Z., Mila-Cáceres, L., Guillén-Nieto, G.E., Fuentes-Aguilar, F., Nordelo-Valdivia, A., GonzálezFernández, N., González-Sarmientos, M., Rubio-Salinas, A., Domínguez-Rabilero, L.C., Espinosa-Peña, R.A., Ramírez-Núñez, Y., Junco-Barranco, J., Díaz-González, O., Fragas-Quintero, A., Pérez-Guevara, M.T., Enriquez-Puertas, J.M., Infante-Hernández, Y., Cruz-Sui, O., NoaRomero, E., López, Yizel Hernández, Sánchez-García, J.E., Rodríguez-Martínez, E., Pimentel-Vázquez, E., Martínez-Díaz, E., Cinza-Estévez, Zurina, Resik-Aguirre, Sonia, Figueroa-Baile, Nelvis L., Oquendo-Martínez, Rachel, Campa-Legrá, Ivan, Tejeda-Fuentes, Alina, Rivero-Caballero, Marila, González-García, Gloria, Chávez-Chong, Cristina O., Alonso-Valdés, Marel, Hernández-Bernal, Francisco, Lemos-Pérez, Gilda, Campal-Espinosa, Ana, Freyre-Corrales, Giselle, Benítez-Gordillo, Delia, Gato-Orozco, Evelyn, Pérez Bartutis, Greter Susana, Mesa-Pedroso, Iliana, Bueno-Alemani, Nilda, Infante-Aguilar, Elizabeth, Rodríguez Reinoso, José Luis, Melo-Suarez, Grettel, Limonta-Fernández, Miladys, Ayala-Ávila, Marta, and Muzio-González, Verena L.

Published
2023
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15. The hidden side of infective endocarditis: Diagnostic and management of 500 consecutive cases in noncardiac surgery centers (2009–2018)

Author

Miró, Jose M., Ambrosioni, Juan, Hernández-Meneses, Marta, Téllez, Adrian, Pericàs, Juan M., Dahl, Anders, Moreno, Asuncion, Aguilar, Sergi, López, Alba, García de la Mària, Cristina, Cañas-Pacheco, María Alejandra, García-González, Javier, Almela, Manel, Zboromyrska, Yuliya, Casals, Climent, Morales, Francisco-Javier, Bosch, Jordi, Marco, Francesc, Vila, Jordi, Quintana, Eduard, Sandoval, Elena, Paré, Juan C., Falces, Carlos, Pereda, Daniel, Cartañá, Ramon, Ninot, Salvador, Azqueta, Manel, Sitges, Marta, Vidal, Barbara, Pomar, José L., Castella, Manuel, Tolosana, José M., Regueiro, Anders, Ortiz, José, Fita, Guillermina, Rovira, Irene, Perissinotti, Andrés, Fuster, David, Ramírez, Jose, Brunet, Mercè, Soy, Dolors, Castro, Pedro, Nicolás, David, Llopis, Jaume, Calzado, Sonia, Gasch, Oriol, Gomila-Grange, Aina, Pedrosa, Marc, Alguacil, Marina, Sanfeliu, Isabel, Guillaumet, Eva, Guillamon, Laura, Caresia, Ana Paula, Díaz, Emilio, Boix-Palop, Lucía, Dietl, Beatriz, Gisbert, Laura, Calbo, Esther, Xercavins, Mariona, Ibars, Sonia, Trenado, Josep, de los Ríos, Javier Díez, Reynaga, Esteban Alberto, Navarro, María, Montserrat, Silvia, Robles, Rocío, Cuquet, Jordi, Arrieta, Itziar, Costa, Núria, Martí, Carmina, Pulido, Ángeles, Ayats, Montserrat, Garro, Pau, Esquirol, Xavier, Bustamante, Marco A., Sanmartí, Montserrat, Cárdenas, Antonio, García, Gloria, Andrés, Marta, García, María Consuelo, Hanacsek, Carme Agustí, Dorca, Esther, Ortiz, María, Roca, Juan Manuel, Mollet, Fundació Sanitària, Tricas, José Maria, Maur, Elisabet, Romeo, Isabel, Vidal-Galve, Rosa, García, Xelo, Agustí, Carme, Tricas, José M., Díez de los Ríos, Javier, and Miró, José M.

Published
2023
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19. Círculos de educación cultural enfermeros: Una estrategia de enseñanza.

Author

González Rendón, Cristina, de Jesús Pérez Vázquez, María, Valdez, Rosa Ávila, Peña García, Gloria María, and Zaldívar Colado, Aníbal

Subjects
NURSING theory, HYPERTENSION, CULTURAL education, NON-communicable diseases, PRIMARY care, CARE ethics (Philosophy), NURSING ethics
Abstract

Copyright of Dilemas Contemporáneos: Educación, Política y Valores is the property of Dilemas Contemporaneos: Educacion, Politica y Valores and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

20. ChatGPT como herramienta educativa en la Licenciatura en Enfermería: perspectivas de los estudiantes.

Author

Peña García, Gloria María, Zaldívar Colado, Aníbal, Medina Gutiérrez, Ana Rosa, Ley Peña, Pedro Alfonso, González Rendón, Cristina, and Ávila Valdéz, Rosa

Subjects
CHATGPT, FOURTH grade (Education), NURSING students, LEARNING, ELEMENTARY schools
Abstract

Copyright of Dilemas Contemporáneos: Educación, Política y Valores is the property of Dilemas Contemporaneos: Educacion, Politica y Valores and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

21. Comparison of Carotid Intima-Media Thickness in Children and Adults With and Without Obesity: A Hysteresis Model

Author

Garibay-Nieto, Nayely, Hernández-Morán, Brianda Areli, Villanueva-Ortega, Eréndira, Garcés-Hernández, María José, Pedraza-Escudero, Karen, Arroyo-Valerio, América, Pedraza-Helvert, César, Herrera-Rosas, Arturo, Laresgoiti-Servitje, Estibalitz, León-Hernández, Mireya, Baltazar-López, Neyla, Hernández-Ruíz, Joselin, Serratos-Canales, Fabiola, Queipo-García, Gloria, Messiah, Sarah Elizabeth, Mummidi, Srinivas, and López-Alvarenga, Juan Carlos

Published
2022
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22. Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded, placebo-controlled, phase 2b/3 trial

Author

Lovesio, Luciano, Diez, Fabián, Grazziani, Franco, Ganaha, Maria Cristina, Zalatnik, Viviana Judith, Dittrich, Ricardo Julio, Espínola, Lidia, Lambert, Sandra, Longhi, Andrea, Vecchio, Claudia, Mastruzzo, María, Fernandez, Alberto, Borchowiek, Silvina, Potito, Roberto, Ahuad Guerrero, Rodolfo Andres, Guardiani, Fernando Martin, Castella, Sofia, Foccoli, Monica, Pedernera, Aldana, Braida, Ariel, Durigan, Virginia, Martella, Carolina, Bobat, Antonela, Boggia, Bruno Emilio, Nemi, Sergio Andrés, Tartaglione, Javier Gerardo, Piedimonte, Fabián César, De Bie, Jessie, Reynales Londoño, Humberto, Rodríguez Ordoñez, Paula Andrea, García Cruz, Johanna Marcela, Bautista Toloza, Leonardo, Ladino González, Margot Cecilia, Zambrano Ochoa, Adriana Pilar, Prieto Pradera, Iñigo, Torres Hernandez, Daniela, Mazo Elorza, Diana Patricia, Collazos Lennis, Maria Fernanda, Vanegas Dominguez, Beatriz, Solano Mosquera, Lina Marianur, Fendel, Rolf, Fleischmann, Wim Alexander, Koehne, Erik, Kreidenweiss, Andrea, Köhler, Carsten, Esen, Meral, Horn, Carola, Eberts, Sandra, Kroidl, Arne, Huber, Kristina, Thiel, Verena, Mazara Rosario, Sonia, Reyes, Gilda, Rivera, Laura, Donastorg, Yeycy, Lantigua, Flavia, Torres Almanzar, Dania, Candelario, Rosalba, Peña Mendez, Lourdes, Rosario Gomez, Nadia, Portolés-Pérez, Antonio, Ascaso del Río, Ana, Laredo Velasco, Leonor, Bustinduy Odriozola, Maria Jesus, Larrea Arranz, Igor, Martínez Alcorta, Luis Ignacio, Durán Laviña, María Isabel, Imaz-Ayo, Natale, Meijide, Susana, García-de-Vicuña, Aitor, Santorcuato, Ana, Gallego, Mikel, Aguirre-García, Gloria Mayela, Olmos Vega, Jocelyn, González Limón, Pablo, Vázquez Villar, Andrea, Chávez Barón, Jaime, Arredondo Saldaña, Felipe, Luján Palacios, Juan de Dios, Camacho Choza, Laura Julia, Vázquez Saldaña, Eduardo Gabriel, Ortega Dominguez, Sandra Janeth, Vega Orozco, Karen Sofia, Torres Quiroz, Ivonne Aimee, Martinez Avendaño, Alejandro, Herrera Sanchez, Javier, Guzman, Esperanza, Castro Castrezana, Laura, Ruiz Palacios y Santos, Guillermo Miguel, de Winter, Ronald Frank Jacobus, de Jonge, Hanna K, Schnyder, Jenny L, Boersma, Wim, Hessels, Lisa, Djamin, Remco, van der Sar, Simone, DeAntonio, Rodrigo, Peña, Moisés, Rebollon, Gabriel, Rojas, Marianela, Escobar, Johnny, Hammerschlag Icaza, Bruno, Wong T, Digna Y, Barrera Perigault, Paulo, Ruiz, Sergio, Chan, Milagros, Arias Hoo, Dommie Janneth, Gil, Ana I, Celis, Carlos R, Balmaceda, Maria Pia, Flores, Omar, Ochoa, Mayra, Peña, Bia, de la Flor, Carolina, Webb, Camille María, Cornejo, Enrique, Sanes, Fatima, Mayorga, Valerie, Valdiviezo, Gladys, Ramírez Lamas, Suzanne Pamela, Grandez Castillo, Gustavo Alberto, Lama, Javier R, Matta Aguirre, Milagros Erika, Arancibia Luna, Lesly Angela, Carbajal Paulet, Óscar, Zambrano Ortiz, José, Camara, Anais, Guzman Quintanilla, Fernanda, Diaz-Parra, Carmen, Morales-Oliva, Jose, Cornejo, Rubelio E, Ricalde, Sheby A, Vidal, Jhonny, Rios Nogales, Luis, Cheatham-Seitz, Darline, Gregoraci, Giorgia, Brecx, Alain, Walz, Lisa, Vahrenhorst, Dominik, Seibel, Tobias, Quintini, Gianluca, Kremsner, Peter G, Ahuad Guerrero, Rodolfo Andrés, Arana-Arri, Eunate, Aroca Martinez, Gustavo Jose, Bonten, Marc, Chandler, Reynaldo, Corral, Gonzalo, De Block, Eddie Jan Louis, Ecker, Lucie, Gabor, Julian Justin, Garcia Lopez, Carlos Alberto, Gonzales, Lucy, Granados González, María Angélica, Gorini, Nestor, Grobusch, Martin P, Hrabar, Adrian D, Junker, Helga, Kimura, Alan, Lanata, Claudio F, Lehmann, Clara, Leroux-Roels, Isabel, Mann, Philipp, Martinez-Reséndez, Michel Fernando, Ochoa, Theresa J, Poy, Carlos Alberto, Reyes Fentanes, Maria Jose, Rivera Mejia, Luis Maria, Ruiz Herrera, Vida Veronica, Sáez-Llorens, Xavier, Schönborn-Kellenberger, Oliver, Schunk, Mirjam, Sierra Garcia, Alexandra, Vergara, Itziar, Verstraeten, Thomas, Vico, Marisa, and Oostvogels, Lidia

Published
2022
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23. Collaborative Mapping and Disability: An Approach from Inclusive Technology to the Experience of the Social Dimension of the City

Author

Arenas, Andrea del Pilar, Castellanos García, Gloria Esperanza, Garzón Carrillo, Edwin Dorance, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Botto-Tobar, Miguel, editor, Cruz, Henry, editor, and Díaz Cadena, Angela, editor

Published
2021
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26. Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors

Author

Wallace-Povirk, Adrianne, Tong, Nian, Wong-Roushar, Jennifer, O'Connor, Carrie, Zhou, Xilin, Hou, Zhanjun, Bao, Xun, Garcia, Gloria E., Li, Jing, Kim, Seongho, Dann, Charles E., III, Matherly, Larry H., and Gangjee, Aleem

Published
2021
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27. Changes in lifestyle resulting from confinement due to COVID-19 and depressive symptomatology: A cross-sectional a population-based study

Author

Manté, Xavier Aldeguer, Casedevall, Judit Bassols, Ginesta, Jordi Barretina, Terradellas, Ramon Brugada, Perxas, Laia Calvó, Colom, Jordi Cid, Real, José Manuel Fernández, Quicios, Jaume Heredia, Bermejo, Abel López, Gragera, Rafael Marcos, del Rio, Ana Molina, Navarrete, José Maria Moreno, Nicolau, Josep Lluís, Martinez, Pascual Ramon Orriols, Compta, Ana Prada, Gutierrez, Salvador Pedraza, Alcántara, Josep Puig, Torrentà, Lluís Ramió, García, Glòria Reig, Serena, Joaquin, Relat, Montse Vendrell, Vilanova, Joan C., Garre-Olmo, Josep, Turró-Garriga, Oriol, Martí-Lluch, Ruth, Zacarías-Pons, Lluís, Alves-Cabratosa, Lia, Serrano-Sarbosa, Domènec, Vilalta-Franch, Joan, and Ramos, Rafel

Published
2021
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31. Everyday Life Infrastructure Impact on Subjective Well-Being in the European Union: A Gender Perspective.

Author

Alarcón-García, Gloria, Ayala Gaytán, Edgardo Arturo, Mayor Balsas, José Manuel, and Quintanilla Domínguez, Claudia María

Subjects
PUBLIC health infrastructure, SUBJECTIVE well-being (Psychology), EVERYDAY life, WELL-being, INFRASTRUCTURE funds, GENDER inequality
Abstract

This paper processes the 2015 Benefits of Gender Equality through Infrastructure Provision (BGEIP) Survey, a representative survey for the EU-28, to estimating the impact of everyday life infrastructure access on subjective well-being (SWB) from a gender perspective in Europe. Our estimations prove that accessing everyday life infrastructure in Europe indeed increases SWB, but it contributes to increasing more the SWB of women than that of men. Women's well-being is positively affected for all kinds of everyday life infrastructures, but the differences with respect to men are larger for the Nursery category for children up to 3 years and for the Centers category for people with long term disabilities. In contrast, men's well-being is only sensitive to the Health infrastructure and to the Gym and Workout places. Clearly, targeting infrastructure investment helping women in caring children, and other dependents in the family constitute an excellent vehicle for increasing women's SWB and reducing gender inequality in Europe. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Primary lateral sclerosis associated with PSEN1 Pro284Leu variant in a Colombian family: Clinical and neuropathological features.

Author

Acosta‐Uribe, Juliana, Villegas‐Lanau, Andrés, Vallejo, Dionis, Ramírez‐Aguilar, Laura, Solano, Juan M., Mejía‐Cupajita, Bárbara, Aguillón, David, Moreno, Sonia, Méndez, Luis G., Baena, Ana, Madrigal, Lucía, Bocanegra, Yamile, Quiroz, Yakeel T., García, Gloria P., Vasquez, Daniel, Arbeláez, Andrés, Lopera, Francisco, Beach, Thomas G., Kosik, Kenneth S., and White, Charles L.

Published
2024
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34. Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study

Author

Quiroz, Yakeel T, Zetterberg, Henrik, Reiman, Eric M, Chen, Yinghua, Su, Yi, Fox-Fuller, Joshua T, Garcia, Gloria, Villegas, Andres, Sepulveda-Falla, Diego, Villada, Marina, Arboleda-Velasquez, Joseph F, Guzmán-Vélez, Edmarie, Vila-Castelar, Clara, Gordon, Brian A, Schultz, Stephanie A, Protas, Hillary D, Ghisays, Valentina, Giraldo, Margarita, Tirado, Victoria, Baena, Ana, Munoz, Claudia, Rios-Romenets, Silvia, Tariot, Pierre N, Blennow, Kaj, and Lopera, Francisco

Published
2020
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40. Caracterización de Síndrome Confusional Agudo en un Hospital de 2do Nivel: Incidencia y Etiologías Comunes

Author

Ramírez Galindo, María del Rayo, Basurto Pérez, María Félix, Torres García, Gloria Beatriz, Carbonell Montes, Luisa Fernanda, Ramírez Galindo, María del Rayo, Basurto Pérez, María Félix, Torres García, Gloria Beatriz, and Carbonell Montes, Luisa Fernanda

Abstract

Acute Confusional Syndrome is of multifactorial origin, characterized by acute alterations of the mental state, frequently reversible and with fluctuation of symptoms (alteration of attention, disorganized thinking and altered alertness). It is an indicator of the quality of hospital care, since the factors involved in its development are preventable. Its evaluation in the emergency room has become more important over time, since this pathology may be a consequence of concomitant conditions whose identification and treatment are a challenge and requiring a specific approach to determine its etiology. A prospective, descriptive and observational study was conducted over a period of one year, with the aim of identifying the incidence of Acute Confusional Syndrome and common etiologies in patients admitted to the emergency department of Hospital General 450; 88 patients were collected, representing an incidence of 0. 23%; with a predominance of male sex (63%), a mean age of 62 years; the most frequent comorbidity was arterial hypertension (42%), with a predominance of the hypoactive subtype (85.2%), and the main etiologies were metabolic (31.8%) and neurological (25%) alterations. Conclusions: Cognitive impairment is an important cause of admission; it is necessary to establish routine diagnostic tests in clinical practice., El Síndrome Confusional Agudo es de origen multifactorial, se caracteriza por alteraciones agudas del estado mental, frecuentemente reversible y con fluctuación de los síntomas (alteración de la atención, pensamiento desorganizado y alteración en el estado de alerta). Es un indicador de la calidad de la atención hospitalaria, pues los factores implicados en su desarrollo son prevenibles. Su evaluación en la sala de urgencias ha tomado mayor importancia con el tiempo, ya que esta patología puede ser consecuencia de padecimientos concomitantes cuya identificación y tratamiento son un desafío y requiere un enfoque específico para la determinación de su etiología. Se realizó un estudio prospectivo, descriptivo y observacional en el periodo de un año, con el objetivo de Identificar la incidencia de Síndrome Confusional Agudo y etiologías comunes en pacientes ingresados a urgencias de Hospital General 450; se recabaron 88 pacientes, lo que representa una incidencia de 0.23%; con predominio del sexo masculino (63%), una edad media de 62 años; la comorbilidad más frecuentes fue la hipertensión arterial (42%), con predominio del subtipo hipoactivo (85.2%), y las principales etiologías fueron alteraciones metabólicas (31.8%) y neurológicas (25%). Conclusiones: El deterioro cognitivo es causa importante de ingreso; es necesario establecer pruebas diagnostica de rutina en la práctica clínica.

Published
2024

41. Prospective secondary teachers’ noticing of students’ thinking about the limit concept: pathways of development

Author

Universidad de Alicante. Departamento de Innovación y Formación Didáctica, Fernández-Verdú, Ceneida, Moreno, Mar, Sánchez-Matamoros García, Gloria, Universidad de Alicante. Departamento de Innovación y Formación Didáctica, Fernández-Verdú, Ceneida, Moreno, Mar, and Sánchez-Matamoros García, Gloria

Abstract

Research has shown that there is a need to examine prospective teachers’ development trajectories related to noticing expertise. An important content in the Spanish high school curriculum (16–18 years old) is the limit concept. Given the importance of this concept in the curriculum and the difficulties some prospective teachers have, developing their noticing of students’ mathematical thinking of this concept in teacher education programs is crucial to achieve high school student mathematics achievement. This study examines how prospective secondary school mathematics teachers (PTs) notice students’ mathematical thinking about the limit concept as they participated in a teaching module. PTs had to anticipate and interpret students’ mathematical understanding and make instructional decisions to support students’ conceptual progression using information about high school students’ understanding of the limit concept. We examined PTs changes related to how they anticipated, interpreted and made instructional decisions during the teaching module. We identified a change in how PTs conceived the understanding of the dynamic limit concept: from all-or-nothing dichotomy to progression; and a change in the instructional decisions they made: from decisions focused on changing the type of discontinuity to conceptual decisions. These changes allow us to characterise development noticing pathways. Our findings also help to identify the teaching module characteristics that support the development of PTs noticing.

Published
2024

42. Farm management practices and host species richness associated with higher likelihood of tuberculosis positive farms in Western Spain

Author

Herrero García, Gloria, Vaz Rodrigues, Rita, Pozo Piñol, Pilar, Barroso, Patricia, Relimpio, David, Nácar, Jesús, Grau, Anna, Mínguez, Olga, García Rodríguez, Alberto, Balseiro, Ana, Gortázar, Christian, Herrero García, Gloria, Vaz Rodrigues, Rita, Pozo Piñol, Pilar, Barroso, Patricia, Relimpio, David, Nácar, Jesús, Grau, Anna, Mínguez, Olga, García Rodríguez, Alberto, Balseiro, Ana, and Gortázar, Christian

Abstract

Gloria Herrero-García is funded by Junta de Castilla y León and FSE (contract ref LE036-20); Rita Vaz-Rodrigues is funded by Universidad de Castilla-La Mancha (UCLM) and ESF (contract ref. 2022/20675); Pilar Pozo is funded by Juan de la Cierva Formación 2021, funded by the Ministerio de Ciencia e Innovación, Agencia Estatal de Investigación and NextGenerationEU/PRTR (contract ref FJC2021-046805-I); Patricia Barroso is funded by a Juan de la Cierva post-doc fellowship (contract ref DC2022-049103-I); and Alberto García-Rodríguez is funded by the EU-NextGenerationEU funds through the 2021–2023 Margarita Salas call for the requalification of the Spanish university system, convened by the Universidad de León, Despite enormous efforts, complete animal tuberculosis (TB) eradication has only been achieved in few regions. Epidemiological analyses are key to identify TB risk factors and set up targeted biosecurity measures. Here, we conducted an in-depth characterization of 84 extensive beef cattle farms from a high TB prevalence region in Western Spain, and assessed how farm management and wildlife presence on farms contribute to cattle TB risk. Twenty-six out of 84 variables were associated with cattle farm TB positivity. Farm management variables associated with TB positivity included older cattle, larger herd size, highly fragmented farm structure and greater connectivity between farms. TB-positive farms provided supplemental feed over a higher number of months, used calf feeders, and had higher number of waterholes. Detecting Eurasian wild boar (Sus scrofa), red fox (Vulpes vulpes), European badger (Meles meles), roe deer (Capreolus capreolus), or Egyptian mongoose (Herpestes ichneumon) on cattle farms was also associated with farm TB positivity. The best ordinal regression model indicated that in farms with a large herd size (> 167 animals) the odds of being positive or recurrently positive (versus negative) was 7.34 (95% CI = 2.43–23.51) times higher that of farms with small herd size. Further, for every additional host species detected in the farm premises, the odds of being TB-positive increased 56%. We conclude that both cattle management and wildlife need to be targeted for successful TB control in grazing-based farming systems., A pesar de los enormes esfuerzos, la erradicación completa de la tuberculosis (TB) animal solo se ha logrado en algunas regiones. Los estudios epidemiológicos son fundamentales para identificar factores de riesgo de TB y establecer medidas de bioseguridad específicas. Aquí, realizamos una caracterización exhaustiva de 84 explotaciones de ganado bovino extensivo en una provincia occidental de España con alta prevalencia de TB bovina, y evaluamos cómo el manejo del ganado y la presencia de fauna silvestre contribuían al riesgo de esta enfermedad. De las 84 variables estudiadas, 26 mostraron asociación con la positividad a TB bovina. Entre las variables de manejo destacaron: ganado de mayor edad, rebaños de mayor tamaño, explotaciones altamente fragmentadas y mayor conectividad entre ganaderías. Asimismo, las explotaciones positivas a TB prolongaban la alimentación suplementaria, utilizaban cebaderos para terneros y tenían un mayor número de charcas. La detección de jabalí (Sus scrofa), zorro (Vulpes vulpes), tejón (Meles meles), corzo (Capreolus capreolus) o meloncillo (Herpestes ichneumon) en las ganaderías también se asoció con la positividad a TB. El mejor modelo de regresión ordinal mostró que en explotaciones con un tamaño de rebaño grande (> 167 animales) las probabilidades de ser positivo o recurrentemente positivo (frente a negativo) eran 7,34 (95 % IC = 2,43–23,51) veces superiores, a las de las explotaciones con un tamaño de rebaño pequeño. Además, por cada especie hospedadora susceptible detectada adicionalmente, la probabilidad de que la ganadería fuese positiva a TB aumentaba un 56 %. Concluimos que tanto el manejo del ganado como la interacción con fauna silvestre deben ser considerados para un control exitoso de la TB en explotaciones con sistemas de pastoreo extensivo., European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Depto. de Sanidad Animal, Fac. de Veterinaria, Centro de Vigilancia Sanitaria Veterinaria (VISAVET), TRUE, pub

Published
2024

43. Waterhole characteristics in tuberculosis positive and negative beef cattle farms from endemic regions in Spain

Author

Junta de Castilla y León, European Commission, Junta de Comunidades de Castilla-La Mancha, Agencia Estatal de Investigación (España), Ministerio de Ciencia e Innovación (España), Ministerio de Ciencia, Innovación y Universidades (España), Universidad de Castilla La Mancha, Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72], Herrero García, Gloria, Barroso, Patricia, Preite, Ludovica, Relimpio, David, Vaz Rodrigues, Rita, Balseiro, Ana, Gortázar, Christian, Junta de Castilla y León, European Commission, Junta de Comunidades de Castilla-La Mancha, Agencia Estatal de Investigación (España), Ministerio de Ciencia e Innovación (España), Ministerio de Ciencia, Innovación y Universidades (España), Universidad de Castilla La Mancha, Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72], Herrero García, Gloria, Barroso, Patricia, Preite, Ludovica, Relimpio, David, Vaz Rodrigues, Rita, Balseiro, Ana, and Gortázar, Christian

Abstract

In dry climates, livestock farming contributes to waterhole creation and maintenance, thereby contributing to biodiversity conservation. However, these lentic water bodies also represent a critical environmental connection between microorganisms and their vertebrate hosts since the water can facilitate pathogen persistence and transmission. Therefore, interventions for tuberculosis (TB) risk mitigation at the wildlife-livestock interface often focus on segregating host species at water points. We hypothesized that waterhole characteristics modulate their use by vertebrates and subsequent pathogen exposure risk. We visited 298 waterholes on 80 TB-positive and 40 TB-negative cattle farms in Spain to assess differences in waterhole characteristics and identify possible management implications. There was an average of 2.7 waterholes per farm. This represents 0.02 waterholes per km2 of farmland and 3.5 m2 of lentic waterbodies per km2 of farmland. Among the studied waterholes, 95% were man-made. Waterholes on TB-positive farms were 42% closer to covering vegetation than waterholes located on TB-negative ones. Farms with man-made waterholes showed a higher risk of TB than those with natural ones. The density of waterholes per surface unit was negatively associated with the farm TB risk. Waterholes placed on TB-positive farms were more intensively trampled by livestock. The best model explained farm positivity to TB as a function of the distance from the waterholes to the nearest cover vegetation, the aquatic vegetation richness found in the waterhole, the intensity of livestock use (trampling), the surrounding waterhole density, and the interaction between waterhole perimeter and the total number of signs of potential wildlife TB hosts per waterhole. Identifying the key waterhole features related to infection risk might allow designing One Health−inspired biosecurity measures such as increasing the number of waterholes, placing new waterholes farther away from cover, or f

Published
2024

44. Trust and power as determinants of tax compliance across 44 nations

Author

Batrancea, Larissa, Nichita, Anca, Olsen, Jerome, Kogler, Christoph, Kirchler, Erich, Hoelzl, Erik, Weiss, Avi, Torgler, Benno, Fooken, Jonas, Fuller, Joanne, Schaffner, Markus, Banuri, Sheheryar, Hassanein, Medhat, Alarcón-García, Gloria, Aldemir, Ceyhan, Apostol, Oana, Bank Weinberg, Diana, Batrancea, Ioan, Belianin, Alexis, Bello Gómez, Felipe de Jesús, Briguglio, Marie, Dermol, Valerij, Doyle, Elaine, Gcabo, Rebone, Gong, Binglin, Ennya, Sara, Essel-Anderson, Anthony, Frecknall-Hughes, Jane, Hasanain, Ali, Hizen, Yoichi, Huber, Odilo, Kaplanoglou, Georgia, Kudła, Janusz, Lemoine, Jérémy E., Leurcharusmee, Supanika, Matthiasson, Thorolfur, Mehta, Sanjeev, Min, Sejin, Naufal, George, Niskanen, Mervi, Nordblom, Katarina, Öztürk, Engin Bağış, Pacheco, Luis, Pántya, József, Rapanos, Vassilis, Roland-Lévy, Christine, Roux-Cesar, Ana Maria, Salamzadeh, Aidin, Savadori, Lucia, Schei, Vidar, Sharma, Manoj, Summers, Barbara, Suriya, Komsan, Tran, Quoc, Villegas-Palacio, Clara, Visser, Martine, Xia, Chun, Yi, Sunghwan, and Zukauskas, Sarunas

Published
2019
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45. Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)

Author

Ramirez Aguilar, Laura, Acosta-Uribe, Juliana, Giraldo, Margarita M., Moreno, Sonia, Baena, Ana, Alzate, Diana, Cuastumal, Rosario, Aguillón, David, Madrigal, Lucía, Saldarriaga, Amanda, Navarro, Alexander, Garcia, Gloria P., Aguirre-Acevedo, Daniel C., Geier, Ethan G., Cochran, J. Nicholas, Quiroz, Yakeel T., Myers, Richard M., Yokoyama, Jennifer S., Kosik, Kenneth S., and Lopera, Francisco

Published
2019
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46. Homozygosity of the autosomal dominant Alzheimer disease presenilin 1 E280A mutation

Author

Kosik, Kenneth S, Muñoz, Claudia, Lopez, Liliana, Arcila, Mary Luz, García, Gloria, Madrigal, Lucía, Moreno, Sonia, Ríos Romenets, Silvia, Lopez, Hugo, Gutierrez, Madelyn, Langbaum, Jessica B, Cho, William, Suliman, Shehnaaz, Tariot, Pierre N, Ho, Carole, Reiman, Eric M, and Lopera, Francisco

Subjects
Adult, Alzheimer Disease, Child, Colombia, Female, Homozygote, Humans, Male, Middle Aged, Mutation, Presenilin-1, Clinical Sciences, Neurosciences, Cognitive Sciences, Neurology & Neurosurgery
Published
2015

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