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Objective: to evaluate the safety of a topical formulation containing chamomile microparticles coated with chitosan in the skin of healthy participants. Method: phase I blind, controlled, nonrandomized, single-dose clinical trial with control for skin, base formulation, and formulation with microparticles. The variables analyzed were irritation and hydration by the Wilcoxon and Kruskall-Wallis tests. Results: the study started with 35 participants with a mean age of 26.3 years. Of these, 30 (85.71%) were female, 29 (82.90%) were white skinned and 32 (91.40%) had no previous pathologies. One participant was removed from the study reporting erythema at the site of application, and four other participants for not attending the last evaluation. In the 30 participants who completed the study, the tested formulation did not cause erythema, peeling, burning, pruritus or pain; there was an improvement in cutaneous hydration in the site of application of the formulation with microparticles. In the evaluation of the barrier function, there was an increase in transepidermal water loss in all sites. Conclusion: the formulation with chamomile microparticles is safe for topical use, not causing irritation and improving skin hydration over four weeks of use. Its effects on barrier function need further investigation. No. RBR-3h78kz in the Brazilian Registry of Clinical Trials (ReBEC). [ABSTRACT FROM AUTHOR]

Aim: The study aimed to characterize phlebitis in adults in a clinical hospitalization sector, in terms of incidence, related factors and grade. Method: This is a cohort carried out in a clinical hospitalization department of a philanthropic hospital in the interior of the state of São Paulo, Brazil. The study included adults over 18 years old, hospitalized and using peripheral venous access; the invitation was made to each patient on their first day of hospitalization and those who accepted signed the informed consent form (ICF), were included, and evaluated daily for the occurrence of phlebitis, as well as its characteristics. A total of 49 people participated in the research, with a mean age of 61.29 years (sd: 20.692), mostly women (69.39%), white (65.30%). Results: The incidence of phlebitis was 28.56%; age over 60 years (p=0.004) and use of anticoagulants (p=0.025) increased the risk of developing phlebitis. The use of intravenous anti-inflammatory drugs (p=0.008) was related to reduce the amount of phlebitis. Conclusion: It was concluded that the incidence of phlebitis was related to age and use of anticoagulants; intravenous anti-inflammatory medications appear to be a protective factor. [ABSTRACT FROM AUTHOR]

The accurate identification of the nursing diagnoses and the corresponding measurement of their indicators will depend on the elements in the standardized language systems. OBJECTIVE: To analyze the correspondence between elements of four NANDA‐I nursing diagnoses and outcomes suggested by the nursing outcomes classification (NOC) for the resolution of these diagnoses. METHOD: A methodological study consisting of cross‐mapping was performed in the first stage between definitions, defining characteristics (DCs), and related factors (RFs) of impaired oral mucous membrane, impaired tissue integrity, spiritual distress, and delayed surgical recovery and outcome definitions and indicators to measure results of diagnoses resolution and an analysis of its relevance by experts in the second stage. RESULTS: It found partial correspondence between outcome indicators, DCs, RFs, and definitions. CONCLUSION: The data evidence the relevance of this review for a reliable application of these taxonomies and demonstrated partial correspondence between concepts analyzed. A identificação precisa dos diagnósticos de enfermagem e a medida correspondente dos seus indicadores dependerá dos elementos nos sistemas de linguagem padronizados. OBJETIVO: Foi analisar a correspondência entre os elementos de quatro NANDA‐I diagnósticos de enfermagem e os resultados sugeridos pelo NOC para a resolução destes diagnósticos. MÉTODO: um estudo metodológico que consiste em cross‐mapping foi realizado em uma primeira fase entre as definições, características definidoras e fatores relacionados de Mucosa oral prejudicada, Integridade tissular prejudicada, Sofrimento espiritual e Recuperação cirúrgica retardada e as definições dos resultados indicados para a resolução destes diagnósticos; na segunda fase, foi realizada uma análise desta concordância por especialistas. RESULTADOS: correspondência parcial entre as definições dos diagnósticos e dos resultados, características definidoras e fatores relacionados. CONCLUSÃO: Os resultados evidenciam a relevância dessa avaliação para uma aplicação confiável destas taxonomias e demonstrou a correspondência parcial entre os conceitos analisados. [ABSTRACT FROM AUTHOR]