1. Associations between urinary bisphenol A and its analogues and semen quality: A cross-sectional study among Chinese men from an infertility clinic
- Author
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Pan-Pan Chen, Chong Liu, Min Zhang, Yu Miao, Fei-Peng Cui, Yan-Ling Deng, Qiong Luo, Jia-Yue Zeng, Tian Shi, Ting-Ting Lu, Wen-Jun Yin, Wen-Qing Lu, Gui-Lin Yi, Gao-Kung Qiu, and Qiang Zeng
- Subjects
Male ,endocrine system ,China ,Fertility Clinics ,urogenital system ,Bisphenol S ,Bisphenols ,urologic and male genital diseases ,Mixture exposure ,Environmental sciences ,Semen Analysis ,Bisphenol A ,Cross-Sectional Studies ,Phenols ,Bisphenol F ,Humans ,GE1-350 ,Benzhydryl Compounds ,Semen quality ,hormones, hormone substitutes, and hormone antagonists ,General Environmental Science - Abstract
Human studies on association between bisphenol A (BPA) exposure and semen quality, mostly based on single urinary measurement, are inconsistent. There is limited human evidence on BPA analogues such as bisphenol F (BPF) and bisphenol S (BPS), and little is known on potential effects of bisphenol mixtures. We aimed to explore whether individual or mixtures of BPA, BPS and BPF assessed in repeated urinary measurements were associated with semen quality among 984 Chinese men from an infertility clinic. We found that higher BPA exposure was associated with increased odds ratios (ORs) of having below-reference sperm concentration, total sperm count, progressive motility and total motility (all P for trends
- Published
- 2022