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17 results on '"Gao, Zidong"'

12. Evaluation of salmon calcitonin (sCT) enteric-coated capsule for enhanced absorption and GI tolerability in rats

Author

Wu, Lei, primary, Zhang, Ge, additional, Lu, Qin, additional, Sun, Qian, additional, Wang, Mulan, additional, Li, Na, additional, Gao, Zidong, additional, Sun, Ya, additional, Li, Tingting, additional, Han, Deen, additional, Yu, Xue, additional, Wang, Lei, additional, Sun, Wei, additional, Zhao, Di, additional, Wu, Yaning, additional, Lu, Yang, additional, and Chen, Xijing, additional

Published
2010
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13. Evaluation of salmon calcitonin (sCT) enteric-coated capsule for enhanced absorption and GI tolerability in rats

Author

Wu, Lei, primary, Zhang, Ge, additional, Lu, Qin, additional, Sun, Qian, additional, Wang, Mulan, additional, Li, Na, additional, Gao, Zidong, additional, Sun, Ya, additional, Li, Tingting, additional, Han, Deen, additional, Yu, Xue, additional, Wang, Lei, additional, Sun, Wei, additional, Zhao, Di, additional, Wu, Yaning, additional, Lu, Yang, additional, and Chen, Xijing, additional

Published
2009
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14. Tunnel mechanization at two underground mines in the People's Republic of China.

Author

Gao Zidong, Chang Dehe, Hei Shuguang, Gao Zidong, Chang Dehe, and Hei Shuguang

Abstract

Improvements in tunnelling rate and production efficiency have been observed as a result of the design and development of new equipment, and extensive field testing in two of China's underground mines. LHD operations at the Xinhuan mercury mine have led to a record rate of advance in China of 1056.8m/month for the construction of a single-head drift of 6.6m2 cross-section. Hard rock tunnelling of a 9m2 cross-section at the Shizhuyuan mine has also been improved by the use of a CJT700.3 three-boom drilling jumbo, LB2-1.50 loader and S-8 shuttle car in combination. Details of both these projects and the equipment employed are outlined., Improvements in tunnelling rate and production efficiency have been observed as a result of the design and development of new equipment, and extensive field testing in two of China's underground mines. LHD operations at the Xinhuan mercury mine have led to a record rate of advance in China of 1056.8m/month for the construction of a single-head drift of 6.6m2 cross-section. Hard rock tunnelling of a 9m2 cross-section at the Shizhuyuan mine has also been improved by the use of a CJT700.3 three-boom drilling jumbo, LB2-1.50 loader and S-8 shuttle car in combination. Details of both these projects and the equipment employed are outlined.

16. Cobalt-Catalyzed Enantioselective Negishi Cross-Coupling of Racemic α-Bromo Esters with Arylzincs.

Author

Liu F, Zhong J, Zhou Y, Gao Z, Walsh PJ, Wang X, Ma S, Hou S, Liu S, Wang M, Wang M, and Bian Q

Abstract

The first cobalt-catalyzed enantioselective Negishi cross-coupling reaction, and the first arylation of α-halo esters with arylzinc halides, are disclosed. Employing a cobalt-bisoxazoline catalyst, various α-arylalkanoic esters were synthesized in excellent enantioselectivities and yields (up to 97 % ee and 98 % yield). A diverse range of functional groups, including ether, halide, thioether, silyl, amine, ester, acetal, amide, olefin and heteroaromatics is tolerated by this method. This method was suitable for gram-scale reactions, enabling the synthesis of (R)-xanthorrhizol with high enantiopurity. Radical clock experiments support the intermediacy of radicals., (© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2018
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17. Palladium-Catalyzed Asymmetric Allylic Alkylations with Toluene Derivatives as Pronucleophiles.

Author

Mao J, Zhang J, Jiang H, Bellomo A, Zhang M, Gao Z, Dreher SD, and Walsh PJ

Subjects
Alkylation, Catalysis, Palladium chemistry, Toluene chemistry
Abstract

The first two highly enantioselective palladium-catalyzed allylic alkylations with benzylic nucleophiles, activated with Cr(CO)3 , have been developed. These methods enable the enantioselective synthesis of α-2-propenyl benzyl motifs, which are important scaffolds in natural products and pharmaceuticals. A variety of cyclic and acyclic allylic carbonates are competent electrophilic partners furnishing the products in excellent enantioselectivity (up to 99 % ee and 92 % yield). This approach was employed to prepare a nonsteroidal anti-inflammatory drug analogue., (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2016
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